K. J. McDowall

发表

Endonucleolytic initiation of mRNA decay in Escherichia coli.

B. Luisi, A. J. Carpousis, K. J. McDowall, 2009, Progress in molecular biology and translational science.

The regulation of the secondary metabolism of Streptomyces: new links and experimental advances.

Gilles P van Wezel, G. V. van Wezel, K. J. McDowall, 2011, Natural product reports.

A comparison of key aspects of gene regulation in Streptomyces coelicolor and Escherichia coli using nucleotide-resolution transcription maps produced in parallel by global and differential RNA sequencing

G. V. van Wezel, V. Kaberdin, L. Mamanova, 2014, Molecular microbiology.

Transcript analysis reveals an extended regulon and the importance of protein-protein co-operativity for the Escherichia coli methionine repressor.

Peter G Stockley, Iain W Manfield, P. Stockley, 2006, The Biochemical journal.

Streptomycin production by Streptomyces griseus can be modulated by a mechanism not associated with change in the adpA component of the A-factor cascade

S. Baumberg, B. Hong, K. J. McDowall, 2006, Biotechnology Letters.

A combination of improved differential and global RNA-seq reveals pervasive transcription initiation and events in all stages of the life-cycle of functional RNAs in Propionibacterium acnes, a major contributor to wide-spread human disease

L. Mamanova, K. J. McDowall, Yu-fei Lin, 2013, BMC Genomics.

Effects of nucleotide sequence on the specificity of rne-dependent and RNase E-mediated cleavages of RNA I encoded by the pBR322 plasmid.

S. Cohen, S. Lin-Chao, T. Wong, 1994, The Journal of biological chemistry.

Dietary zinc oxide affects the expression of genes associated with inflammation: Transcriptome analysis in piglets challenged with ETEC K88.

M. Shaw, H. Miller, K. J. McDowall, 2010, Veterinary immunology and immunopathology.

Quaternary structure and catalytic activity of the Escherichia coli ribonuclease E amino-terminal catalytic domain.

C. Robinson, B. Luisi, J. G. Grossmann, 2003, Biochemistry.

Direct entry by RNase E is a major pathway for the degradation and processing of RNA in Escherichia coli

K. J. McDowall, Louise Kime, Justin E Clarke, 2014, Nucleic acids research.

Enhanced cleavage of RNA mediated by an interaction between substrates and the arginine-rich domain of E. coli ribonuclease E.

V. Kaberdin, A. Gabain, K. J. McDowall, 2000, Journal of molecular biology.

The recognition of structured elements by a conserved groove distant from domains associated with catalysis is an essential determinant of RNase E

K. J. McDowall, Louise Kime, Justin E Clarke, 2023, Nucleic acids research.

A stereodivergent, two-directional synthesis of stereoisomeric C-linked disaccharide mimetics.

A. Nelson, K. J. McDowall, T. Majid, 2003, Organic & biomolecular chemistry.

Phosphate Control of Oxytetracycline Production by Streptomyces rimosus Is at the Level of Transcription from Promoters Overlapped by Tandem Repeats Similar to Those of the DNA-Binding Sites of the OmpR Family

I. Hunter, K. J. McDowall, A. Thamchaipenet, 1999, Journal of bacteriology.

Regulation of antibiotic production in Actinobacteria: new perspectives from the post-genomic era.

G. V. van Wezel, R. Seipke, K. J. McDowall, 2018, Natural product reports.

RNA Stability: Chemistry, Measurement and Modulation

K. J. McDowall, 2008 .

Identifying and characterizing substrates of the RNase E/G family of enzymes.

S. Jourdan, K. J. McDowall, Louise Kime, 2008, Methods in enzymology.

Cleavage of poly(A) tails on the 3'-end of RNA by ribonuclease E of Escherichia coli.

V. Kaberdin, K. J. McDowall, A. von Gabain, 2001, Nucleic acids research.

The CafA Protein Required for the 5′-Maturation of 16 S rRNA Is a 5′-End-dependent Ribonuclease That Has Context-dependent Broad Sequence Specificity*

K. J. McDowall, A. P. Walsh, M. R. Tock, 2000, The Journal of Biological Chemistry.

Expanding the use of zymography by the chemical linkage of small, defined substrates to the gel matrix.

V. Kaberdin, K. J. McDowall, K. McDowall, 2003, Genome research.

Transcriptional activation of the pathway‐specific regulator of the actinorhodin biosynthetic genes in Streptomyces coelicolor

S. Baumberg, K. J. McDowall, J. Stead, 2005, Molecular microbiology.

The permease gene nagE2 is the key to N‐acetylglucosamine sensing and utilization in Streptomyces coelicolor and is subject to multi‐level control

G. V. van Wezel, H. Nothaft, S. Rigali, 2010, Molecular microbiology.

The endoribonucleolytic N-terminal half of Escherichia coli RNase E is evolutionarily conserved in Synechocystis sp. and other bacteria but not the C-terminal half, which is sufficient for degradosome assembly.

V. Kaberdin, S. Lin-Chao, A. Gabain, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Structure of Escherichia coli RNase E catalytic domain and implications for RNA turnover

W. Scott, B. Luisi, K. J. McDowall, 2005, Nature.

Sensing of 5′ monophosphate by Escherichia coli RNase G can significantly enhance association with RNA and stimulate the decay of functional mRNA transcripts in vivo

S. Jourdan, K. J. McDowall, 2007, Molecular microbiology.

The ams-1 and rne-3071 temperature-sensitive mutations in the ams gene are in close proximity to each other and cause substitutions within a domain that resembles a product of the Escherichia coli mre locus

S. Cohen, S. Lin-Chao, K. J. McDowall, 1993, Journal of bacteriology.

RNase E: still a wonderfully mysterious enzyme

K. J. McDowall, S. Cohen, K. McDowall, 1997, Molecular microbiology.

The N-terminal domain of the rne gene product has RNase E activity and is non-overlapping with the arginine-rich RNA-binding site.

S. Cohen, K. J. McDowall, K. McDowall, 1996, Journal of molecular biology.

Site-specific RNase E cleavage of oligonucleotides and inhibition by stem–loops

Stanley N Cohen, V. Kaberdin, S. Lin-Chao, 1995, Nature.

A+U content rather than a particular nucleotide order determines the specificity of RNase E cleavage.

S. Cohen, S. Lin-Chao, K. J. McDowall, 1994, The Journal of biological chemistry.

The Regulation of the Secondary Metabolism of Streptomyces: New Links and Experimental Advances

K. J. McDowall, G. P. Wezel, 2011 .

Transcriptional analysis of the cell division-related ssg genes in Streptomyces coelicolor reveals direct control of ssgR by AtrA

G. V. van Wezel, Byung-gee Kim, Songhee H. Kim, 2015, Antonie van Leeuwenhoek.

An Improved Binary Vector and Escherichia coli Strain for Agrobacterium tumefaciens-Mediated Plant Transformation

P. Meyer, E. Hollwey, Michael Watson, 2016, G3: Genes, Genomes, Genetics.

Translational activation by the noncoding RNA DsrA involves alternative RNase III processing in the rpoS 5'-leader.

T. Afonyushkin, V. Kaberdin, U. Bläsi, 2008, RNA.

Characterization of an oxytetracycline‐resistance gene, otrA, of Streptomyces rimosus

I. Hunter, M. Butler, K. J. McDowall, 1991, Molecular microbiology.

Differential expression and extent of fungal/plant and fungal/bacterial chitinases of Aspergillus fumigatus

J. Pinney, D. Westhead, K. J. McDowall, 2005, Archives of Microbiology.

A Combined In Vitro Transposition-In Vivo Recombination Mutagenesis Method to Knock Out Genes in Escherichia coli

P. Stockley, K. J. McDowall, F. Marincs, 2004 .

Protein-conjugated microbubbles for the selective targeting of S. aureus biofilms

S. Evans, S. Freear, J. Sandoe, 2022, Biofilm.

Cross Inoculation of Rumen Fluid to Improve Dry Matter Disappearance and Its Effect on Bacterial Composition Using an in vitro Batch Culture Model

K. J. McDowall, Henry Greathead, K. McDermott, 2020, Frontiers in Microbiology.

"Zn-link": a metal-sharing interface that organizes the quaternary structure and catalytic site of the endoribonuclease, RNase E.

C. Robinson, B. Luisi, E. Garman, 2005, Biochemistry.

Adjacent single-stranded regions mediate processing of tRNA precursors by RNase E direct entry

J. Grasby, K. J. McDowall, Louise Kime, 2014, Nucleic acids research.

The Identification of Nucleic Acid-interacting Proteins Using a Simple Proteomics-based Approach That Directly Incorporates the Electrophoretic Mobility Shift Assay *

K. J. McDowall, J. Keen, Kenneth J McDowall, 2006, Molecular & Cellular Proteomics.

Two-dimensional gel electrophoresis for identifying proteins that bind DNA or RNA

K. J. McDowall, J. Stead, 2007, Nature Protocols.

The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family

C. Fishwick, Deena M. A. Gendoo, S. Jourdan, 2015, Scientific Reports.

Rapid cleavage of RNA by RNase E in the absence of 5′ monophosphate stimulation

S. Jourdan, K. J. McDowall, Louise Kime, 2009, Molecular microbiology.

Determination of the Catalytic Parameters of the N-terminal Half of Escherichia coli Ribonuclease E and the Identification of Critical Functional Groups in RNA Substrates*

V. Kaberdin, J. Grasby, C. Adams, 2003, Journal of Biological Chemistry.

The sequence of sites recognised by a member of the RNase E/G family can control the maximal rate of cleavage, while a 5'-monophosphorylated end appears to function cooperatively in mediating RNA binding.

S. Jourdan, K. J. McDowall, Louise Kime, 2010, Biochemical and biophysical research communications.