D. Chiappetta

发表

Current understanding of nanoparticle toxicity mechanisms and interactions with biological systems

M. Garcés, L. Cáceres, D. Chiappetta, 2021, New Journal of Chemistry.

Enhanced oral bioavailability of the antiretroviral efavirenz encapsulated in poly(epsilon-caprolactone) nanoparticles by a spray-drying method.

D. Chiappetta, H. Swai, A. Sosnik, 2014, Nanomedicine.

Enantioselective pharmacokinetics and cardiovascular effects of nebivolol in L-NAME hypertensive rats

D. Chiappetta, J. Mauro, C. Taira, 2014, Hypertension Research.

Acute effects of third generation β-blockers on short-term and beat-to-beat blood pressure variability in sinoaortic-denervated rats

D. Chiappetta, J. Mauro, C. Taira, 2013, Hypertension Research.

Effect of nebivolol on beat-to-beat and short-term blood pressure variability in spontaneously hypertensive rats

D. Chiappetta, J. Mauro, C. Taira, 2012, Naunyn-Schmiedeberg's Archives of Pharmacology.

Enantioselective pharmacokinetic and pharmacodynamic properties of carvedilol in spontaneously hypertensive rats: focus on blood pressure variability

D. Chiappetta, J. Mauro, C. Taira, 2011, Naunyn-Schmiedeberg's Archives of Pharmacology.

Asymmetric IgG Antibodies Induced by Different Immunotherapies in a Murine Model of Allergy

D. Chiappetta, C. Bregni, C. Apicella, 2009, Immunological investigations.

The transferrin receptor and the targeted delivery of therapeutic agents against cancer.

Ezequiel Bernabeu, Gustavo Helguera, T. Daniels, 2012, Biochimica et biophysica acta.

Intranasal administration of antiretroviral-loaded micelles for anatomical targeting to the brain in HIV.

D. Chiappetta, A. Sosnik, C. Hocht, 2013, Nanomedicine.

Nanotechnology in Tuberculosis: State of the Art and the Challenges Ahead

D. Chiappetta, M. Moretton, E. Bernabeu, 2018, Pharmaceutical Research.

Paclitaxel-loaded PCL-TPGS nanoparticles: in vitro and in vivo performance compared with Abraxane®.

G. Helguera, D. Chiappetta, C. Hocht, 2014, Colloids and surfaces. B, Biointerfaces.

Thinking small, doing big: Current success and future trends in drug delivery systems for improving cancer therapy with special focus on liver cancer.

D. Chiappetta, M. Moretton, E. Bernabeu, 2019, Materials science & engineering. C, Materials for biological applications.

Novel Soluplus(®)-TPGS mixed micelles for encapsulation of paclitaxel with enhanced in vitro cytotoxicity on breast and ovarian cancer cell lines.

D. Chiappetta, M. Moretton, E. Bernabeu, 2016, Colloids and surfaces. B, Biointerfaces.

Hydrolyzed galactomannan-modified nanoparticles and flower-like polymeric micelles for the active targeting of rifampicin to macrophages.

B. Sarmento, J. das Neves, D. Chiappetta, 2013, Journal of biomedical nanotechnology.

Colloids and Surfaces B: Biointerfaces

D. Chiappetta, A. Sosnik, Katia P. Seremeta, 2013 .

Deoxycholate-TPGS mixed nanomicelles for encapsulation of methotrexate with enhanced in vitro cytotoxicity on breast cancer cell lines

D. Chiappetta, M. Moretton, E. Bernabeu, 2019, Journal of Drug Delivery Science and Technology.

Glycosylated paclitaxel mixed nanomicelles: Increasing drug brain accumulation and enhancing its in vitro antitumoral activity in glioblastoma cell lines

S. Lompardía, S. Hajos, D. Chiappetta, 2021, Journal of Drug Delivery Science and Technology.

Nanopolymersomes as potential carriers for rifampicin pulmonary delivery.

D. Chiappetta, M. Moretton, E. Bernabeu, 2015, Colloids and surfaces. B, Biointerfaces.

Efavirenz is a substrate and in turn modulates the expression of the efflux transporter ABCG2/BCRP in the gastrointestinal tract of the rat.

D. Chiappetta, A. Sosnik, C. Hocht, 2011, Biochemical pharmacology.

Episcleral implants for topotecan delivery to the posterior segment of the eye.

D. Chiappetta, A. Carcaboso, D. Abramson, 2010, Investigative ophthalmology & visual science.

Drug delivery systems in HIV pharmacotherapy: what has been done and the challenges standing ahead.

D. Chiappetta, A. Carcaboso, A. Sosnik, 2009, Journal of controlled release : official journal of the Controlled Release Society.

New and developing pharmacotherapies for hypertension

D. Chiappetta, M. Moretton, A. Carranza, 2022, Expert review of cardiovascular therapy.

Herbal buccal films with in vitro antibacterial and anti-inflammatory effects

D. Chiappetta, M. B. Nuñez, Cristina M. Pérez Zamora, 2021, Journal of Herbal Medicine.

Mixed micelles for encapsulation of doxorubicin with enhanced in vitro cytotoxicity on breast and ovarian cancer cell lines versus Doxil®.

D. Chiappetta, M. Zubillaga, M. Moretton, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Micro-encapsulated secretory leukocyte protease inhibitor decreases cell-mediated immune response in autoimmune orchitis.

L. Lustig, D. Chiappetta, P. Jacobo, 2011, Life sciences.

Detection and characterization of circulating microvesicles containing Shiga toxin type 2 (Stx2) in a rat model of Hemolytic Uremic Syndrome

D. Chiappetta, C. Jancic, M. Moretton, 2022, bioRxiv.

Topotecan vitreous levels after periocular or intravenous delivery in rabbits: an alternative for retinoblastoma chemotherapy.

M. D. de Dávila, D. Chiappetta, A. Carcaboso, 2007, Investigative ophthalmology & visual science.

Novel 1-indanone Thiosemicarbazone Antiviral Candidates: Aqueous Solubilization and Physical Stabilization by Means of Cyclodextrins

D. Chiappetta, A. Moglioni, A. Sosnik, 2011, Pharmaceutical Research.

The Topical Nanodelivery of Vismodegib Enhances Its Skin Penetration and Performance In Vitro While Reducing Its Toxicity In Vivo

S. Alonso, D. Chiappetta, D. Ybarra, 2021, Pharmaceutics.

Comparison of the Acute Antihypertensive Response to Telmisartan and Irbesartan in Spontaneously Hypertensive Rats

D. Chiappetta, J. Mauro, C. Taira, 2016 .

Zebrafish (Danio rerio) model as an early stage screening tool to study the biodistribution and toxicity profile of doxorubicin‐loaded mixed micelles

S. Alonso, D. Chiappetta, M. Calienni, 2018, Toxicology and applied pharmacology.

99mTc-Radiolabeled TPGS Nanomicelles Outperform 99mTc-Sestamibi as Breast Cancer Imaging Agent

D. Chiappetta, M. Salgueiro, Mariel A Núñez, 2019, Contrast media & molecular imaging.

Tc-Sestamibi as Breast Cancer Imaging Agent

D. Chiappetta, Mariel A Núñez, V. Medina, 2019 .

Effect of nebivolol on beat-to-beat and short-term blood pressure variability in spontaneously hypertensive rats

D. Chiappetta, J. Mauro, C. Taira, 2012, Naunyn-Schmiedeberg's Archives of Pharmacology.

Synergistic encapsulation of the anti-HIV agent efavirenz within mixed poloxamine/poloxamer polymeric micelles.

E. R. de Celis, D. Chiappetta, A. Sosnik, 2011, Nanomedicine : nanotechnology, biology, and medicine.

Solubility of the Antimicrobial Agent Triclosan in Organic Solvents of Different Hydrogen Bonding Capabilities at Several Temperatures

F. Martínez, D. Chiappetta, A. Sosnik, 2008 .

Monitoring the microenvironment inside polymeric micelles using the fluorescence probe 6-propionyl-2-dimethylaminonaphthalene (PRODAN)

N. M. Correa, J. Silber, D. Chiappetta, 2021, Journal of Molecular Liquids.

Enhanced oral bioavailability of nevirapine within micellar nanocarriers compared with Viramune(®).

D. Chiappetta, M. Moretton, C. Taira, 2014, Colloids and surfaces. B, Biointerfaces.

Poly(ethylene oxide)-poly(propylene oxide) block copolymer micelles as drug delivery agents: improved hydrosolubility, stability and bioavailability of drugs.

D. Chiappetta, Alejandro Sosnik, Diego A Chiappetta, 2007, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Oral pharmacokinetics of the anti-HIV efavirenz encapsulated within polymeric micelles.

D. Chiappetta, A. Sosnik, C. Hocht, 2011, Biomaterials.

N-alkylation of poloxamines modulates micellar assembly and encapsulation and release of the antiretroviral efavirenz.

A. Concheiro, C. Alvarez‐Lorenzo, P. Taboada, 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Efavirenz-loaded polymeric micelles for pediatric anti-HIV pharmacotherapy with significantly higher oral bioavailability [corrected].

D. Chiappetta, A. Sosnik, C. Hocht, 2010, Nanomedicine.

Gibbs energy of transfer processes for the antimicrobial agent Triclosan from water to some organic solvents at 25.0 °C

F. Martínez, D. Chiappetta, A. Sosnik, 2008 .

Triclosan-loaded poloxamine micelles for enhanced topical antibacterial activity against biofilm.

D. Chiappetta, A. Sosnik, C. Bregni, 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Novel nelfinavir mesylate loaded d-α-tocopheryl polyethylene glycol 1000 succinate micelles for enhanced pediatric anti HIV therapy: In vitro characterization and in vivo evaluation.

S. Lucangioli, D. Chiappetta, M. Moretton, 2014, Colloids and surfaces. B, Biointerfaces.

Novel 1-indanone Thiosemicarbazone Antiviral Candidates: Aqueous Solubilization and Physical Stabilization by Means of Cyclodextrins

D. Chiappetta, A. Moglioni, A. Sosnik, 2012, Pharmaceutical Research.

Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties.

M. Jobbágy, D. Chiappetta, A. Sosnik, 2013, Biomacromolecules.

Lipid-based microtubes for topical delivery of amphotericin B.

D. Chiappetta, A. Arechavala, S. L. Scioscia, 2013, Colloids and surfaces. B, Biointerfaces.

Polymeric mixed micelles as nanomedicines: Achievements and perspectives.

D. Chiappetta, M. Salgueiro, M. Zubillaga, 2017, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Cryoprotection–lyophilization and physical stabilization of rifampicin-loaded flower-like polymeric micelles

D. Chiappetta, A. Sosnik, M. Moretton, 2012, Journal of The Royal Society Interface.

Single and mixed poloxamine micelles as nanocarriers for solubilization and sustained release of ethoxzolamide for topical glaucoma therapy

A. Concheiro, C. Alvarez‐Lorenzo, F. Veiga, 2012, Journal of The Royal Society Interface.

New old challenges in tuberculosis: potentially effective nanotechnologies in drug delivery.

D. Chiappetta, A. Carcaboso, Alejandro Sosnik, 2010, Advanced drug delivery reviews.

Release study of diclofenac from new carbomer gels.

D. Chiappetta, A. Carlucci, C. Bregni, 2008, Pakistan journal of pharmaceutical sciences.

Inhibition of fluconazole in vitro antifungal activity in formulations containing propylene glycol

D. Chiappetta, A. Carlucci, C. Bregni, 2011 .

Polymeric micelles and nanomedicines: Shaping the future of next generation therapeutic strategies for infectious diseases

D. Chiappetta, M. Moretton, E. Bernabeu, 2021, Journal of Drug Delivery Science and Technology.

Pulmonary delivery of rifampicin-loaded soluplus micelles against Mycobacterium tuberculosis

D. Chiappetta, M. Manconi, M. Manca, 2019, Journal of Drug Delivery Science and Technology.

Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery

B. Sarmento, F. Goycoolea, D. Chiappetta, 2011 .

Nanomicellar Formulations Loaded with Histamine and Paclitaxel as a New Strategy to Improve Chemotherapy for Breast Cancer

M. R. Rubinstein, D. Chiappetta, M. Salgueiro, 2023, International journal of molecular sciences.

Paclitaxel and curcumin co-loaded mixed micelles: Improving in vitro efficacy and reducing toxicity against Abraxane®

S. Alonso, D. Chiappetta, P. Evelson, 2021, Journal of Drug Delivery Science and Technology.

Self-aggregation behaviour of novel thiosemicarbazone drug candidates with potential antiviral activity

D. Chiappetta, L. Finkielsztein, A. Moglioni, 2010 .

Carvedilol stability in paediatric oral liquid formulations.

D. Chiappetta, C. Bregni, F. Buontempo, 2010, Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria.

A glucose‐targeted mixed micellar formulation outperforms Genexol in breast cancer cells

D. Chiappetta, M. Zubillaga, M. Moretton, 2017, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Doxorubicin: nanotechnological overviews from bench to bedside.

D. Chiappetta, M. Moretton, E. Bernabeu, 2017, Drug discovery today.

Influence of surfactant structure in the encapsulation and stability of amphotericin B in niosomes

D. Chiappetta, C. Bregni, C. Salerno, 2011 .

Novel formulation and drug delivery strategies for the treatment of pediatric poverty-related diseases

D. Chiappetta, A. Sosnik, Katia P. Seremeta, 2012, Expert opinion on drug delivery.

Advances in therapy for the prevention of HIV transmission from mother to child

D. Chiappetta, M. Moretton, F. Bertera, 2017, Expert opinion on pharmacotherapy.

Paclitaxel: What has been done and the challenges remain ahead.

D. Chiappetta, M. Moretton, E. Bernabeu, 2017, International journal of pharmaceutics.

Novel carvedilol paediatric nanomicelle formulation: in‐vitro characterization and in‐vivo evaluation

D. Chiappetta, M. Moretton, C. Taira, 2017, The Journal of pharmacy and pharmacology.

Novel long-term anticonvulsant treatment with gabapentin without causing memory impairment in mice

M. Boccia, M. Krawczyk, D. Chiappetta, 2010, Epilepsy & Behavior.

Characterization and bioavailability of a novel Coenzyme Q10 nanoemulsion used as an infant formula supplement.

S. Lucangioli, D. Chiappetta, V. Tripodi, 2023, International journal of pharmaceutics.

Sustained-release hydrogels of topotecan for retinoblastoma.

D. Chiappetta, G. Chantada, M. Moretton, 2016, Colloids and surfaces. B, Biointerfaces.

Molecular implications in the nanoencapsulation of the anti-tuberculosis drug rifampicin within flower-like polymeric micelles.

D. Chiappetta, A. Sosnik, M. Moretton, 2010, Colloids and surfaces. B, Biointerfaces.

Polymeric Nanocarriers: New Endeavors for the Optimization of the Technological Aspects of Drugs

D. Chiappetta, A. Carcaboso, A. Sosnik, 2008 .

Indinavir-Loaded pH-Sensitive Microparticles for Taste Masking: Toward Extemporaneous Pediatric Anti-HIV/AIDS Liquid Formulations with Improved Patient Compliance

D. Chiappetta, A. Carcaboso, A. Sosnik, 2009, AAPS PharmSciTech.

A highly concentrated and taste-improved aqueous formulation of efavirenz for a more appropriate pediatric management of the anti-HIV therapy.

D. Chiappetta, A. Sosnik, C. Hocht, 2010, Current HIV research.

Tetronic® 904-containing polymeric micelles overcome the overexpression of ABCG2 in the blood-brain barrier of rats and boost the penetration of the antiretroviral efavirenz into the CNS.

D. Chiappetta, A. Sosnik, C. Hocht, 2015, Nanomedicine.

Poly(ε-caprolactone), Eudragit® RS 100 and poly(ε-caprolactone)/Eudragit® RS 100 blend submicron particles for the sustained release of the antiretroviral efavirenz.

D. Chiappetta, A. Sosnik, Katia P. Seremeta, 2013, Colloids and surfaces. B, Biointerfaces.

In vitro/in vivo characterization of melt-molded gabapentin-loaded poly(epsilon-caprolactone) implants for sustained release in animal studies.

M. Boccia, D. Chiappetta, M. Blake, 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Antitumor efficacy and cardiotoxic effect of doxorubicin-loaded mixed micelles in 4T1 murine breast cancer model. Comparative studies using Doxil® and free doxorubicin

S. Vanzulli, D. Chiappetta, M. Salgueiro, 2020 .

Extemporaneous clobazam suspensions for paediatric use prepared from commercially available tablets and pure drug.

D. Chiappetta, M. Moretton, F. Buontempo, 2013, Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria.

Polymeric Nanomicelles Loaded with Anandamide and Their Renal Effects as a Therapeutic Alternative for Hypertension Treatment by Passive Targeting

M. Fornés, D. Chiappetta, M. Salgueiro, 2023, Pharmaceutics.

Nanoscale Kolliphor® HS 15 micelles to minimize rifampicin self-aggregation in aqueous media

D. Chiappetta, M. Moretton, E. Bernabeu, 2017 .

Effects of third-generation β-blockers, atenolol or amlodipine on blood pressure variability and target organ damage in spontaneously hypertensive rats.

D. Chiappetta, G. González, S. Gorzalczany, 2020, Journal of hypertension.

Vitamin E TPGS Used as Emulsifier in the Preparation of Nanoparticulate Systems

Ezequiel Bernabeu, Diego A. Chiappetta, D. Chiappetta, 2013 .

Inhalable Mannosylated Rifampicin–Curcumin Co-Loaded Nanomicelles with Enhanced In Vitro Antimicrobial Efficacy for an Optimized Pulmonary Tuberculosis Therapy

M. Garcés, D. Chiappetta, P. Evelson, 2022, Pharmaceutics.

Nebivolol is more effective than atenolol for blood pressure variability attenuation and target organ damage prevention in L-NAME hypertensive rats

D. Chiappetta, G. González, P. Prince, 2021, Hypertension Research.

Pharmacokinetic and pharmacodynamic properties of carvedilol in fructose hypertensive rats

D. Chiappetta, C. Taira, F. Bertera, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

Enantioselective pharmacokinetic–pharmacodynamic modelling of carvedilol in a NG‐nitro‐l‐arginine methyl ester rat model of secondary hypertension

D. Chiappetta, C. Taira, F. Bertera, 2010, The Journal of pharmacy and pharmacology.

Effects of carvedilol or amlodipine on target organ damage in L-NAME hypertensive rats: their relationship with blood pressure variability.

D. Chiappetta, G. González, S. Gorzalczany, 2017, Journal of the American Society of Hypertension : JASH.

Nanotechnology in Tuberculosis: State of the Art and the Challenges Ahead

D. Chiappetta, M. Moretton, E. Bernabeu, 2018, Pharmaceutical Research.

Enantioselective pharmacokinetic and pharmacodynamic properties of carvedilol in spontaneously hypertensive rats: focus on blood pressure variability

D. Chiappetta, J. Mauro, C. Taira, 2012, Naunyn-Schmiedeberg's Archives of Pharmacology.

Development of Subcutaneous Implants of Controlled Release Formulations of Carvedilol for Sustained Blood Pressure Reduction in Experimental Models of Hypertension

D. Chiappetta, M. Moretton, F. Bertera, 2020 .

Paclitaxel-Loaded TPGS-b-PCL Nanoparticles: In Vitro Cytotoxicity and Cellular Uptake in MCF-7 and MDA-MB-231 Cells versus mPEG-b-PCL Nanoparticles and Abraxane®.

D. Chiappetta, M. Moretton, E. Bernabeu, 2016, Journal of Nanoscience and Nanotechnology.

Radiolabeling and biological characterization of TPGS-based nanomicelles by means of small animal imaging.

D. Chiappetta, M. Salgueiro, M. Zubillaga, 2017, Nuclear medicine and biology.

Enhanced oral bioavailability of the antiretroviral efavirenz encapsulated in poly(epsilon-caprolactone) nanoparticles by a spray-drying method.

D. Chiappetta, H. Swai, A. Sosnik, 2014, Nanomedicine.

Soluplus® nanomicelles enhance IgG neutralizing properties against Shiga toxin type 2

D. Chiappetta, M. Moretton, F. Sacerdoti, 2024, Journal of Drug Delivery Science and Technology.

Dual strategy to improve the oral bioavailability of efavirenz employing nanomicelles and curcumin as a bio-enhancer.

M. Garcés, D. Chiappetta, P. Evelson, 2023, International journal of pharmaceutics.