H. Chacun

发表

Poly(ethylene glycol)-Coated Hexadecylcyanoacrylate Nanospheres Display a Combined Effect for Brain Tumor Targeting

G. Vassal, P. Couvreur, I. Brigger, 2002, Journal of Pharmacology and Experimental Therapeutics.

Translocation of poly(ethylene glycol-co-hexadecyl)cyanoacrylate nanoparticles into rat brain endothelial cells: role of apolipoproteins in receptor-mediated endocytosis.

Patrick Couvreur, Myriam Taverna, P. Couvreur, 2007, Biomacromolecules.

Analysis of plasma protein adsorption onto PEGylated nanoparticles by complementary methods: 2‐DE, CE and Protein Lab‐on‐chip® system

P. Couvreur, M. Appel, D. Georgin, 2007, Electrophoresis.

Low-density lipoprotein receptor-mediated endocytosis of PEGylated nanoparticles in rat brain endothelial cells

P. Couvreur, V. Nicolas, M. Appel, 2007, Cellular and Molecular Life Sciences.

Interactions between the dopamine agonist, bromocriptine and the efflux protein, P-glycoprotein at the blood-brain barrier in the mouse.

R. Farinotti, L. Lacomblez, H. Chacun, 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Long-Circulating PEGylated Polycyanoacrylate Nanoparticles as New Drug Carrier for Brain Delivery

P. Couvreur, E. Fattal, D. Georgin, 2001, Pharmaceutical Research.

Intestinal permeation enhancement of docetaxel encapsulated into methyl-β-cyclodextrin/poly(isobutylcyanoacrylate) nanoparticles coated with thiolated chitosan.

G. Ponchel, K. Bouchemal, H. Chacun, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Transmembrane diffusion of gemcitabine by a nanoparticulate squalenoyl prodrug: an original drug delivery pathway.

P. Couvreur, V. Nicolas, C. Dubernet, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Role of two efflux proteins, ABCB1 and ABCG2 in blood-brain barrier transport of bromocriptine in a murine model of MPTP-induced dopaminergic degeneration.

R. Farinotti, L. Lacomblez, H. Chacun, 2009, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.

Direct evidence of abca1-mediated efflux of cholesterol at the mouse blood–brain barrier

F. Calon, R. Farinotti, G. Chimini, 2011, Molecular and Cellular Biochemistry.

Extracellular-protein-enhanced cellular uptake of squalenoyl gemcitabine from nanoassemblies

P. Couvreur, C. Dubernet, D. Desmaële, 2010 .

Targeting of 3′-Azido 3′-Deoxythymidine (AZT)-Loaded Poly(Isohexylcyanoacrylate) Nanospheres to the Gastrointestinal Mucosa and Associated Lymphoid Tissues

G. Ponchel, H. Chacun, J. Gantier, 2001, Pharmaceutical Research.

Squalenoylation Favorably Modifies the in Vivo Pharmacokinetics and Biodistribution of Gemcitabine in Mice

A. Paci, G. Vassal, P. Couvreur, 2008, Drug Metabolism and Disposition.

Towards an Improved anti‐HIV Activity of NRTI via Metal–Organic Frameworks Nanoparticles

H. Willaime, P. Couvreur, C. Serre, 2013, Advanced healthcare materials.

Gene Expression of a Protein, JB70, Related to Rat α1-Acid Glycoprotein inEuglena gracilis

H. Chacun, D. Porquet, G. Durand, 1997 .

Establishment of an in vitro model expressing the folate receptor for the investigation of targeted delivery systems

P. Couvreur, P. Colombo, B. Stella, 2005 .

Mucoadhesive paclitaxel-loaded chitosan-poly (isobutyl cyanoacrylate) core-shell nanocapsules containing copaiba oil designed for oral drug delivery

C. Vauthier, E. Egito, H. Chacun, 2019, Journal of Drug Delivery Science and Technology.

Novel composite core-shell nanoparticles as busulfan carriers.

J. Benoit, C. Passirani, R. Gref, 2006, Journal of controlled release : official journal of the Controlled Release Society.

Spongelike alginate nanoparticles as a new potential system for the delivery of antisense oligonucleotides.

P. Couvreur, C. Vauthier, E. Fattal, 1999, Antisense & nucleic acid drug development.

Intravitreal delivery of oligonucleotides by sterically stabilized liposomes.

P. Couvreur, J. Jeanny, E. Fattal, 2002, Investigative ophthalmology & visual science.

Stabilization and cellular delivery of chitosan-polyphosphate nanoparticles by incorporation of iron.

E. Fattal, H. Hillaireau, H. Chacun, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Skin Localization of Cow’s Milk Proteins Delivered by a New Ready-to-Use Atopy Patch Test

G. Ponchel, P. Legrand, G. Barratt, 2005, Pharmaceutical Research.

Gastrointestinal Transit and Mucoadhesion of Colloidal Suspensions of Lycopersicon Esculentum L. and Lotus Tetragonolobus Lectin-PLA Microsphere Conjugates in Rats

G. Ponchel, H. Chacun, D. Duchěne, 2001, Pharmaceutical Research.

Modulation of intestinal barrier properties by miltefosine.

R. Farinotti, G. Barratt, M. Buyse, 2006, Biochemical pharmacology.

Specific permeability modulation of intestinal paracellular pathway by chitosan-poly(isobutylcyanoacrylate) core-shell nanoparticles.

I. Bravo-Osuna, G. Ponchel, C. Vauthier, 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Encapsulation of mono- and oligo-nucleotides into aqueous-core nanocapsules in presence of various water-soluble polymers.

J. Janin, P. Couvreur, H. Hillaireau, 2007, International journal of pharmaceutics.

Encapsulation of antiviral nucleotide analogues azidothymidine-triphosphate and cidofovir in poly(iso-butylcyanoacrylate) nanocapsules.

J. Janin, P. Couvreur, H. Hillaireau, 2006, International journal of pharmaceutics.

A new nanomedicine based on didanosine glycerolipidic prodrug enhances the long term accumulation of drug in a HIV sanctuary.

A. Paci, G. Vassal, P. Couvreur, 2011, International journal of pharmaceutics.

Oatp1a4 and an L-thyroxine-sensitive transporter mediate the mouse blood-brain barrier transport of amyloid-β peptide.

R. Farinotti, H. Chacun, C. Yapo, 2013, Journal of Alzheimer's disease : JAD.

PLA-PEG Nanoparticles Improve the Anti-Inflammatory Effect of Rosiglitazone on Macrophages by Enhancing Drug Uptake Compared to Free Rosiglitazone

E. Fattal, N. Tsapis, H. Chacun, 2018, Materials.

Growth responses of achlorophyllous Euglena gracilis to selected concentrations of cadmium and pentachlorophenol

H. Chacun, Y. Bourezgui, J. Barque, 1995, Archives of environmental contamination and toxicology.

Interactions between riluzole and ABCG2/BCRP transporter

Gilbert Bensimon, Vincent Meininger, V. Meininger, 2009, Neuroscience Letters.

Squalenoyl Adenosine Nanoparticles provide Neuroprotection after Stroke and Spinal Cord Injury

P. Couvreur, V. Nicolas, N. Hildebrandt, 2014, Nature nanotechnology.

Altered cerebral vascular volumes and solute transport at the blood–brain barriers of two transgenic mouse models of Alzheimer's disease

F. Calon, R. Farinotti, L. Pradier, 2014, Neuropharmacology.

Formulation and Pharmacokinetics of Thermosensitive Stealth® Liposomes Encapsulating 5-Fluorouracil

A. Novell, J. Escoffre, E. Fattal, 2014, Pharmaceutical Research.

Paclitaxel-loaded PEGylated nanocapsules of perfluorooctyl bromide as theranostic agents.

J. Valette, E. Fattal, N. Tsapis, 2016, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Immunodetection of a protein related to mammalian arrestin in Euglena gracilis.

H. Chacun, J. Faure, M. Mirshahi, 1997, Biochemical and biophysical research communications.

International Society for Therapeutic Ultrasound Conference 2016

Megan E Poorman, Eric L. Miller, Jonathan T. Sutton, 2017, Journal of Therapeutic Ultrasound.

ABCG2- and ABCG4-mediated efflux of amyloid-β peptide 1-40 at the mouse blood-brain barrier.

F. Calon, R. Farinotti, M. Buyse, 2012, Journal of Alzheimer's disease : JAD.

Pharmacokinetics, biodistribution and metabolism of squalenoyl adenosine nanoparticles in mice using dual radio-labeling and radio-HPLC analysis

P. Couvreur, A. Gaudin, J. Mougin, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Ultrasound‐induced mild hyperthermia improves the anticancer efficacy of both Taxol® and paclitaxel‐loaded nanocapsules

A. Paci, B. Larrat, E. Fattal, 2017, Journal of controlled release : official journal of the Controlled Release Society.

Busulfan loading into poly(alkyl cyanoacrylate) nanoparticles: physico-chemistry and molecular modeling.

P. Couvreur, J. Poupaert, N. Ghermani, 2006, Journal of biomedical materials research. Part B, Applied biomaterials.

Nanoencapsulation of a crystalline drug.

P. Couvreur, A. Domb, M. Appel, 2005, International journal of pharmaceutics.

Cationic emulsions improves the delivery of oligonucleotides to leukemic P388/ADR cells in ascite.

L. Rabinovich, P. Couvreur, S. Benita, 2003, Journal of Controlled Release.

Formulation and Pharmacokinetics of Thermosensitive Stealth® Liposomes Encapsulating 5-Fluorouracil

A. Novell, J. Escoffre, E. Fattal, 2015, Pharmaceutical Research.

Interactions between antiparkinsonian drugs and ABCB1/P-glycoprotein at the blood–brain barrier in a rat brain endothelial cell model

R. Farinotti, M. Buyse, H. Chacun, 2008, Neuroscience Letters.