P. Marchetti

发表

Mitochondrial proliferation during apoptosis induced by anticancer agents: effects of doxorubicin and mitoxantrone on cancer and cardiac cells

S. Lancel, C. Bailly, C. Fournier, 2004, Oncogene.

Clinically Relevant Oxygraphic Assay to Assess Mitochondrial Energy Metabolism in Acute Myeloid Leukemia Patients

B. Quesnel, C. Berthon, J. Kluza, 2021, Cancers.

Targeting Chelatable Iron as a Therapeutic Modality in Parkinson ’ s Disease

L. Defebvre, K. Dujardin, A. Destée, 2016 .

Regulation by survivin of cancer cell death induced by F14512, a polyamine-containing inhibitor of DNA topoisomerase II

C. Bailly, J. Kluza, P. Marchetti, 2012, Apoptosis.

Glucose metabolism and NRF2 coordinate the antioxidant response in melanoma resistant to MAPK inhibitors

B. Quesnel, G. Garçon, M. Malet‐Martino, 2018, Cell Death & Disease.

[Are mitochondria targets of anticancer drugs responsible for apoptosis?].

L. Mortier, P. Marchetti, P. Formstecher, 2002, Annales de biologie clinique.

Progression of actinic keratosis to squamous cell carcinoma of the skin correlates with deletion of the 9p21 region encoding the p16(INK4a) tumor suppressor.

L. Mortier, P. Marchetti, P. Formstecher, 2002, Cancer letters.

Apoptosis in Pneumonia

J. Pittet, B. Guery, P. Marchetti, 2002 .

The functionality of mitochondria differentiates human spermatozoa with high and low fertilizing capability.

P. Marchetti, Frédérique Gallon, C. Marchetti, 2006, Fertility and sterility.

Effects of Mycoplasma fermentans on the myelomonocytic lineage. Different molecular entities with cytokine-inducing and cytocidal potential.

G. Kroemer, S. Roman-Roman, M. Castedo, 1996, Journal of immunology.

The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition

G. Kroemer, J. Reed, R. Kofler, 1998, Oncogene.

Mitochondrial oxidative phosphorylation controls cancer cell's life and death decisions upon exposure to MAPK inhibitors

S. Lancel, B. Quesnel, F. André, 2016, Oncotarget.

Increased CD271 expression by the NF-kB pathway promotes melanoma cell survival and drives acquired resistance to BRAF inhibitor vemurafenib

P. Abbe, C. Bertolotto, R. Ballotti, 2015, Cell Discovery.

Lamellarin Alkaloids: Structure and Pharmacological Properties

C. Bailly, J. Kluza, P. Marchetti, 2007 .

The Presence of Apoptotic Bone Marrow Cells Impairs the Efficacy of Cardiac Cell Therapy

R. Neviere, G. Lemesle, F. Mouquet, 2011, Cell transplantation.

Mitochondrial dysfunction is an essential step for killing of non-small cell lung carcinomas resistant to conventional treatment

B. Joseph, G. Kroemer, B. Zhivotovsky, 2002, Oncogene.

TRPC3 shapes the ER-mitochondria Ca2+ transfer characterizing tumour-promoting senescence

D. Metzger, D. Bernard, E. Germain, 2022, Nature communications.

Influence of heat stress on human monocyte‐derived dendritic cell functions with immunotherapeutic potential for antitumor vaccines

T. Velu, P. Gosset, L. Mortier, 2007, Journal of leukocyte biology.

Apoptosis of cells lacking mitochondrial DNA

G. Kroemer, P. Petit, P. Marchetti, 1996, Apoptosis.

Mitochondrial permeability transition triggers lymphocyte apoptosis.

G. Kroemer, M. Castedo, D. Decaudin, 1996, Journal of immunology.

Terminal differentiation of human epidermal keratinocytes involves mitochondria- and caspase-dependent cell death pathway

L. Mortier, P. Marchetti, P. Formstecher, 2003, Cell Death and Differentiation.

Chelatable Iron as a Therapeutic Modality in Parkinson's Disease

K. Dujardin, D. Devos, A. Duhamel, 2013 .

Apoptosis-inducing factor determines the chemoresistance of non-small-cell lung carcinomas

B. Joseph, G. Kroemer, B. Zhivotovsky, 2004, Oncogene.

Expression of apoptosis regulatory factors during myocardial dysfunction in endotoxemic rats*

R. Favory, S. Lancel, R. Neviere, 2005, Critical care medicine.

Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis.

G. Kroemer, M. Castedo, A. Macho, 1996, Journal of immunology.

Study of AMPK-Regulated Metabolic Fluxes in Neurons Using the Seahorse XFe Analyzer.

L. Buée, V. Vingtdeux, J. Kluza, 2018, Methods in molecular biology.

Inhibition of mitochondrial permeability transition prevents sepsis-induced myocardial dysfunction and mortality.

R. Favory, S. Lancel, Brigitte Decoster, 2006, Journal of the American College of Cardiology.

Protective effects of cyclosporin A from endotoxin-induced myocardial dysfunction and apoptosis in rats.

R. Neviere, C. Chopin, P. Marchetti, 2002, American journal of respiratory and critical care medicine.

Caspase inhibition prevents cardiac dysfunction and heart apoptosis in a rat model of sepsis.

R. Neviere, C. Chopin, P. Marchetti, 2001, American journal of respiratory and critical care medicine.

Differential effects of caspase inhibitors on endotoxin-induced myocardial dysfunction and heart apoptosis.

R. Neviere, C. Chopin, P. Marchetti, 2001, American journal of physiology. Heart and circulatory physiology.

Endotoxin-induced myocardial dysfunction: Evidence for a role of sphingosine production*

S. Mordon, R. Favory, S. Lancel, 2004, Critical care medicine.

Differential Roles of Nand C-Terminal Immunoreceptor Tyrosine-Based Inhibition Motifs During Inhibition of Cell Activation by Killer Cell Inhibitory Receptors 1

W. Fridman, P. Bruhns, É. Vivier, 1999 .

Killer Cell Inhibitory Receptors Motifs During Inhibition of Cell Activation by Immunoreceptor Tyrosine-Based Inhibition Differential Roles of Nand C-Terminal

W. Fridman, P. Bruhns, É. Vivier, 1999 .

ANNEXIN V DETECTION OF LIPOPOLYSACCHARIDE-INDUCED CARDIAC APOPTOSIS

G. Slegers, S. Lancel, R. Neviere, 2007, Shock.

Doxorubicin-induced cardiac dysfunction is attenuated by ciclosporin treatment in mice through improvements in mitochondrial bioenergetics.

S. Lancel, R. Neviere, J. Beauvillain, 2011, Clinical science.

L'apoptose : bases fondamentales et applications médicales

P. Marchetti, P. Marchetti, 2005 .

Sphingosine impairs mitochondrial function by opening permeability transition pore.

R. Favory, S. Lancel, Brigitte Decoster, 2006, Mitochondrion.

Cigarette smoke alters the ability of human dendritic cells to promote anti-Streptococcus pneumoniae Th17 response

O. Le Rouzic, M. Pichavant, P. Gosset, 2016, Respiratory Research.

Defective caspase-3 relocalization in non-small cell lung carcinoma

B. Joseph, B. Zhivotovsky, R. Lewensohn, 2001, Oncogene.

Plasma membrane potential in thymocyte apoptosis.

G. Kroemer, D. Métivier, H. Duc, 1999, Journal of immunology.

T. Velu, L. Mortier, P. Marchetti, 2008, Journal of cellular and molecular medicine.

Stabilization of mitochondrial membrane potential prevents doxorubicin-induced cardiotoxicity in isolated rat heart.

S. Lancel, R. Neviere, P. Marchetti, 2010, Toxicology and applied pharmacology.

Mitochondrial permeability transition in apoptosis and necrosis

G. Kroemer, P. Marchetti, N. Zamzami, 1998, Cell Biology and Toxicology.

Farnesoid X Receptor Inhibits Glucagon-Like Peptide-1 Production by Enteroendocrine L-cells

F. Bäckhed, F. Pattou, F. Reimann, 2015, Nature Communications.

Apoptosis inhibition in P. aeruginosa-induced lung injury influences lung fluid balance

J. Pittet, K. Faure, B. Guery, 2004, Intensive Care Medicine.

GILZ overexpression attenuates endoplasmic reticulum stress-mediated cell death via the activation of mitochondrial oxidative phosphorylation.

B. Quesnel, F. André, T. Idziorek, 2016, Biochemical and biophysical research communications.

Another Facet to the Anticancer Response to Lamellarin D: Induction of Cellular Senescence through Inhibition of Topoisomerase I and Intracellular Ros Production

A. Martoriati, L. Mortier, J. Kluza, 2014, Marine drugs.

The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death

G. Kroemer, P. Marchetti, N. Zamzami, 1997, Oncogene.

Staining of human sperm with fluorochrome-labeled inhibitor of caspases to detect activated caspases: correlation with apoptosis and sperm parameters.

P. Marchetti, Miguel-Angel Gallego, P. Formstecher, 2004, Human reproduction.

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

G. Kroemer, E. Daugas, M. Castedo, 1996, The Journal of experimental medicine.

A New Strategy to Preserve and Assess Oxygen Consumption in Murine Tissues

G. Garçon, F. Pinet, E. Dubois-Deruy, 2021, International journal of molecular sciences.

Disease Modifying Strategy Based upon Iron Chelation in Parkinson's Disease: A Translational Study (P02.240)

L. Defebvre, K. Dujardin, A. Destée, 2012 .

The myocardial uptake of 123I — annexin V is increased in septic rats

G. Slegers, R. Neviere, P. Marchetti, 2001 .

Heat Shock Protein 72 Does Not Modulate Ionizing Radiation-Induced Apoptosis in U1810 Non-Small Cell Lung Carcinoma Cells

B. Joseph, B. Zhivotovsky, R. Lewensohn, 2003, Cancer biology & therapy.

Study of mitochondrial membrane potential, reactive oxygen species, DNA fragmentation and cell viability by flow cytometry in human sperm.

P. Marchetti, P. Formstecher, C. Marchetti, 2002, Human reproduction.

Inhibition of mitochondrial respiration mediates apoptosis induced by the anti-tumoral alkaloid lamellarin D

Christian Bailly, S. Lancel, R. Neviere, 2010, Apoptosis.

Essential role of mitochondria in apoptosis of cancer cells induced by the marine alkaloid Lamellarin D

Christian Bailly, B. Joseph, C. Bailly, 2009, Molecular Cancer Therapeutics.

Cancer cell mitochondria are direct proapoptotic targets for the marine antitumor drug lamellarin D.

Jérôme Kluza, Christian Bailly, C. Bailly, 2006, Cancer research.

Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis

G. Kroemer, M. Castedo, P. Marchetti, 1996, FEBS letters.

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo

G. Kroemer, P. Petit, J. Vayssière, 1995, The Journal of experimental medicine.

Redox regulation of apoptosis: Impact of thiol oxidation status on mitochondrial function

G. Kroemer, A. Macho, D. Decaudin, 1997, European journal of immunology.

Mitochondrial control of nuclear apoptosis

G. Kroemer, I. Gomez-Monterrey, M. Castedo, 1996, The Journal of experimental medicine.

Mitochondrial dysfunctions in circulating T lymphocytes from human immunodeficiency virus-1 carriers.

G. Kroemer, J. Uriel, M. Castedo, 1995, Blood.

Mitochondrial permeability transition is a central coordinating event of apoptosis

G. Kroemer, M. Castedo, A. Macho, 1996, The Journal of experimental medicine.

Comparison of four fluorochromes for the detection of the inner mitochondrial membrane potential in human spermatozoa and their correlation with sperm motility.

P. Marchetti, P. Formstecher, A. Defossez, 2004, Human reproduction.

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

G. Kroemer, P. Petit, B. Mignotte, 1995, The Journal of experimental medicine.

Determination of Mitochondrial Membrane Potential by Flow Cytometry in Human Sperm Cells

P. Marchetti, C. Marchetti, N. Jouy, 2021 .

Inactivation of the HIF-1α/PDK3 signaling axis drives melanoma toward mitochondrial oxidative metabolism and potentiates the therapeutic activity of pro-oxidants.

M. Bernaudin, S. Valable, M. Malet‐Martino, 2012, Cancer research.

PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection.

G. Kroemer, N. Larochette, D. Decaudin, 1998, Experimental cell research.

Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437

G. Kroemer, H. Vieira, C. Brenner, 2001, Oncogene.

Regulation by survivin of cancer cell death induced by F14512, a polyamine-containing inhibitor of DNA topoisomerase II

C. Bailly, J. Kluza, P. Marchetti, 2012, Apoptosis.

Lipid Metabolism and Resistance to Anticancer Treatment

J. Kluza, P. Marchetti, Quentin Fovez, 2020, Biology.

Mitochondrial oxidative stress is the achille's heel of melanoma cells resistant to Braf-mutant inhibitor

G. Garçon, S. Rocchi, M. Malet‐Martino, 2013, Oncotarget.

Lactate Inhibits the Pro-Inflammatory Response and Metabolic Reprogramming in Murine Macrophages in a GPR81-Independent Manner

J. Sirard, S. Offermanns, Cong Tang, 2016, PloS one.

Mitochondrial dysfunction is an essential step for killing of non-small cell lung carcinomas resistant to conventional treatment

B. Joseph, G. Kroemer, B. Zhivotovsky, 2002, Oncogene.

The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid can trigger apoptosis through a mitochondrial pathway independent of the nucleus.

B. Joseph, G. Kroemer, P. Marchetti, 1999, Cancer research.

Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents.

G. Kroemer, R. Kofler, S. Geley, 1997, Cancer research.

Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo

G. Kroemer, J. Uriel, M. Castedo, 1995, European journal of immunology.

Ventricular Myocyte Caspases Are Directly Responsible for Endotoxin-Induced Cardiac Dysfunction

R. Favory, S. Lancel, R. Neviere, 2005, Circulation.

Does Apoptosis Play a Role in the Development of Sepsis-Induced Myocardial Dysfunction?

R. Neviere, P. Marchetti, 2002 .

Maintenance of the T lymphocyte pool by inhibition of apoptosis: a novel strategy of immunostimulation?

G. Kroemer, M. Castedo, P. Marchetti, 1995, Current topics in microbiology and immunology.

Influence of mitochondrial membrane potential of spermatozoa on in vitro fertilisation outcome

P. Marchetti, C. Ballot, C. Marchetti, 2012, Andrologia.

Metabolic targeting of cancer by a ubiquinone uncompetitive inhibitor of mitochondrial complex I.

E. Stickeler, Shashi Jain, D. Wolf, 2021, Cell chemical biology.

Exploiting Mitochondrial Dysfunction for Effective Elimination of Imatinib-Resistant Leukemic Cells

B. Quesnel, M. Malet‐Martino, T. Idziorek, 2011, PloS one.

Mitochondrial spare respiratory capacity: Mechanisms, regulation, and significance in non‐transformed and cancer cells

J. Kluza, P. Marchetti, Quentin Fovez, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Overcoming chemoresistance of non-small cell lung carcinoma through restoration of an AIF-dependent apoptotic pathway

B. Joseph, G. Kroemer, C. Bailly, 2008, Oncogene.

Differential roles of N- and C-terminal immunoreceptor tyrosine-based inhibition motifs during inhibition of cell activation by killer cell inhibitory receptors.

W. Fridman, P. Bruhns, É. Vivier, 1999, Journal of immunology.

Mitochondrial Electron Transport Is the Cellular Target of the Oncology Drug Elesclomol

Corey Nislow, Marinella Gebbia, Guri Giaever, 2012, PloS one.

Patient-derived tumor xenograft strategies for informed management of patients with metastatic melanoma

L. Mortier, J. Kluza, P. Marchetti, 2016, Melanoma research.

Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA.

G. Kroemer, J. Naval, M. Castedo, 1996, Cancer research.

Melanoma metabolism contributes to the cellular responses to MAPK/ERK pathway inhibitors.

J. Kluza, P. Marchetti, A. Trinh, 2018, Biochimica et biophysica acta. General subjects.

Integration of Mitochondrial Targeting for Molecular Cancer Therapeutics

Pierre Guerreschi, L. Mortier, J. Kluza, 2015, International journal of cell biology.

Pertussis toxin‐sensitive GTP‐binding proteins regulate activation‐induced apoptotic cell death of human natural killer cells

G. Kroemer, P. Marchetti, J. Carracedo, 1995, European journal of immunology.

Patient-derived tumor xenograft model to guide the use of BRAF inhibitors in metastatic melanoma

D. Huglo, L. Ravasi, L. Mortier, 2013, Melanoma research.

The novel retinoid AHPN/CD437 induces a rapid but incomplete apoptotic response in human myeloma cells.

B. Joseph, P. Marchetti, S. Schraen-Maschke, 2003, Biochimica et biophysica acta.

Detection of apoptosis and apoptosis-associated alterations

G. Kroemer, C. Martínez-A, L. Boscá, 1996 .

Air pollution-derived PM2.5 impairs mitochondrial function in healthy and chronic obstructive pulmonary diseased human bronchial epithelial cells.

G. Garçon, A. Loyens, S. Anthérieu, 2018, Environmental pollution.

Glucose metabolism and NRF2 coordinate the antioxidant response in melanoma resistant to MAPK inhibitors

B. Quesnel, G. Garçon, M. Malet‐Martino, 2018, Cell Death & Disease.

AMP-Activated Protein Kinase Is Essential for the Maintenance of Energy Levels during Synaptic Activation

L. Buée, D. Balschun, V. Vingtdeux, 2018, bioRxiv.

Induction of apoptosis-like mitochondrial impairment triggers antioxidant and Bcl-2-dependent keratinocyte differentiation.

J. Beauvillain, L. Mortier, P. Marchetti, 2005, The Journal of investigative dermatology.

Chlorpromazine amplifies macrophage-dependent IL-10 production in vivo.

G. Kroemer, N. Van Rooijen, N. Rooijen, 1995, Journal of immunology.

Glutathione depletion is an early and calcium elevation is a late event of thymocyte apoptosis.

G. Kroemer, A. Macho, P. Marchetti, 1997, Journal of immunology.

Antimetabolic cooperativity with the clinically approved kidrolase and tyrosine kinase inhibitors to eradicate cml stem cells

B. Quesnel, B. Turcq, T. Idziorek, 2020, bioRxiv.

First-line Screening of OXPHOS Deficiencies Using Microscale Oxygraphy in Human Skin Fibroblasts: A Preliminary Study

J. Kluza, P. Marchetti, W. Laine, 2019, International journal of medical sciences.

Dormant tumor cells develop cross-resistance to apoptosis induced by CTLs or imatinib mesylate via methylation of suppressor of cytokine signaling 1.

B. Quesnel, P. Marchetti, F. Colucci, 2007, Cancer research.

Methylation of Suppressor of Cytokine Signaling 1 Apoptosis Induced by CTLs or Imatinib Mesylate via Dormant Tumor Cells Develop Cross-Resistance to

B. Quesnel, P. Marchetti, F. Colucci, 2007 .

mitochondrial oxidative damage and calcium overload , both potent inducers of the mitochondrial permeability transition , are common events during acute and chronic doxorubicin treatment both in vitro and in vivo (

S. Lancel, R. Neviere, P. Marchetti, 2010 .

Caspase-dependent protein phosphatase 2A activation contributes to endotoxin-induced cardiomyocyte contractile dysfunction*

S. Lancel, Brigitte Decoster, R. Neviere, 2010, Critical care medicine.

Metabolic rewiring in cancer cells overexpressing the glucocorticoid-induced leucine zipper protein (GILZ): Activation of mitochondrial oxidative phosphorylation and sensitization to oxidative cell death induced by mitochondrial targeted drugs.

B. Quesnel, M. Malet‐Martino, F. André, 2017, The international journal of biochemistry & cell biology.

Metabolic features of melanoma: a gold mine of new therapeutic targets?

L. Mortier, J. Kluza, P. Marchetti, 2014, Current cancer drug targets.

Deregulation of the hypoxia inducible factor-1α pathway in monocytes from sporadic amyotrophic lateral sclerosis patients

L. Defebvre, A. Destée, D. Devos, 2011, Neuroscience.

Normalization and scaling effects on1H NMR spectra in a metabolomics analysis of leukemic cells

M. Malet‐Martino, J. Kluza, P. Marchetti, 2015 .

Clinical response under MEK inhibitor alone in metastatic melanoma with a novel fusion involving the RAF1 gene

L. Mortier, P. Marchetti, P. Jamme, 2023, Melanoma research.

Identification of IgG-specific Oligoclonal Banding in Serum and Cerebrospinal Fluid by Isoelectric Focusing: Description of a Simplified Method for the Diagnosis of Neurological Disorders

P. Marchetti, J. Gutiérrez, P. Formstecher, 1999, Clinical chemistry and laboratory medicine.

Mitochondrial alterations triggered by repeated exposure to fine (PM2.5-0.18) and quasi-ultrafine (PM0.18) fractions of ambient particulate matter.

G. Garçon, A. Loyens, S. Anthérieu, 2020, Environment international.

The Mitochondrion as a Sensor/Effector of Oxidative Stress During Apoptosis

G. Kroemer, P. Marchetti, N. Zamzami, 1997 .