K. Takada

发表

Liquid filled nanoparticles as a drug delivery tool for protein therapeutics.

N. Shibata, N. Venkatesan, J. Yoshimitsu, 2005, Biomaterials.

Evaluation of factors to decrease bioavailability of cyclosporin A in rats with gentamicin-induced acute renal failure.

G. Spiteller, Asako Nishimura, N. Shibata, 2004, Biological & pharmaceutical bulletin.

Sustained-release self-dissolving micropiles for percutaneous absorption of insulin in mice

Kanji Takada, Atsushi Saeki, Yukako Ito, 2007, Journal of drug targeting.

Antigen-loaded dissolving microneedle array as a novel tool for percutaneous vaccination.

Kanji Takada, M. Kataoka, Yukako Ito, 2012, Vaccine.

Two-layered dissolving microneedles formulated with intermediate-acting insulin.

Keizo Fukushima, Kanji Takada, Yukako Ito, 2012, International journal of pharmaceutics.

Three-layered microcapsules as a long-term sustained release injection preparation.

Keizo Fukushima, Kanji Takada, Yukako Ito, 2010, International journal of pharmaceutics.

In vivo effects of cyclosporin A and ketoconazole on the pharmacokinetics of representative substrates for P-glycoprotein and cytochrome P450 (CYP) 3A in rats.

N. Shibata, Yukako Ito, K. Takada, 2005, Biological & pharmaceutical bulletin.

Gastro-intestinal patch system for the delivery of erythropoietin.

N. Shibata, N. Venkatesan, K. Takada, 2006, Journal of controlled release : official journal of the Controlled Release Society.

Effects of oxidative stress on the pharmacokinetics and hepatic metabolism of atazanavir in rats

Yukako Ito, K. Takada, H. Aoyama, 2013, Free radical research.

Pharmacokinetics of clomipramine, an antidepressant, in poloxamer 407‐induced hyperlipidaemic model rats

Yukako Ito, K. Takada, K. Fukushima, 2011, The Journal of pharmacy and pharmacology.

Effects of obesity induced by high‐fat diet on the pharmacokinetics of nelfinavir, a HIV protease inhibitor, in laboratory rats

Yukako Ito, K. Takada, K. Fukushima, 2009, Biopharmaceutics & drug disposition.

Pharmacokinetics of human immunodeficiency virus protease inhibitor, nelfinavir, in poloxamer 407-induced hyperlipidemic model rats.

K. Takada, K. Fukushima, N. Sugioka, 2009, Biological & pharmaceutical bulletin.

Enhancing effect of absorption promoters on percutaneous absorption of a model dye (6-carboxyfluorescein) as poorly absorbable drugs. II. Study on the absorption promoting effect of azone.

K. Takada, S. Muranishi, T. Ohshima, 1985, Journal of pharmacobio-dynamics.

Decrease in brain distribution of fluvoxamine in experimental hyperlipidemic rats.

K. Takada, K. Fukushima, N. Sugioka, 2011, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.

Evaluation of carbamazepine pharmacokinetic profiles in mice with kainic acid-induced acute seizures.

Asako Nishimura, N. Shibata, K. Takada, 2008, Biological & pharmaceutical bulletin.

Clinical pharmacokinetics of mycophenolate mofetil in Japanese renal transplant recipients: A retrospective cohort study in a single center.

N. Shibata, Yukako Ito, K. Takada, 2006, Biological & pharmaceutical bulletin.

A Dissolution Test for a Pressure‐controlled Colon Delivery Capsule: Rotating Beads Method

K. Takada, H. Yoshikawa, G. Kimura, 1999, The Journal of pharmacy and pharmacology.

Effect of glycerol-induced acute renal failure on the pharmacokinetics of lidocaine after transdermal application in rats.

N. Shibata, K. Takada, Y. Yoshikawa, 2003, Biological & pharmaceutical bulletin.

Decrease in oral bioavailability of ciclosporin by intravenous pulse of methylprednisolone succinate in rats

N. Shibata, K. Takada, T. Minouchi, 2004, The Journal of pharmacy and pharmacology.

Influence of intravenous methylprednisolone pulse treatment on the disposition of ciclosporin and hepatic CYP3A activity in rats

N. Shibata, K. Takada, T. Minouchi, 2004, The Journal of pharmacy and pharmacology.

Dissolving Microneedles as Skin Allergy Test Device.

T. Sakaeda, Yukako Ito, K. Takada, 2017, Biological & pharmaceutical bulletin.

Physiologically based pharmacokinetics of KNI‐272, a tripeptide HIV‐1 protease inhibitor

A. Kiriyama, K. Takada, T. Nishiura, 1999, Biopharmaceutics & drug disposition.

Dissolving microneedles for enhanced local delivery of capsaicin to rat skin tissue

T. Sakaeda, Yukako Ito, K. Takada, 2017, Journal of drug targeting.

Evaluation of an intestinal pressure-controlled colon delivery capsules prepared by a dipping method.

Y. Jeong, N. Shibata, K. Takada, 2001, Journal of controlled release : official journal of the Controlled Release Society.

Insulin micropiles comprising biodegradable polymers for production of a long-term hypoglycemic effect

Yukako Ito, K. Takada, K. Fukushima, 2011, Journal of drug targeting.

Effects of Cholestasis on Whole Blood Concentration of Tacrolimus, an Immunosuppressant, in Living-Related Liver Transplant Recipients

K. Takada, N. Yoshimura, K. Fukushima, 2013 .

A predictive biomarker for altered 5‐fluorouracil pharmacokinetics following repeated administration in a rat model of colorectal cancer

Asako Nishimura, N. Shibata, Yukako Ito, 2013, Biopharmaceutics & drug disposition.

Effect of cyclosporine on drug transport and pharmacokinetics of nifedipine.

K. Naruhashi, Asako Nishimura, N. Shibata, 2009, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Gastrointestinal mucoadhesive patch system (GI-MAPS) for oral administration of G-CSF, a model protein.

N. Shibata, K. Takada, Y. Yoshikawa, 2002, Biomaterials.

Pre-therapeutic assessment of plasma dihydrouracil/uracil ratio for predicting the pharmacokinetic parameters of 5-fluorouracil and tumor growth in a rat model of colorectal cancer.

Yukako Ito, K. Takada, S. Kobuchi, 2013, Biological & pharmaceutical bulletin.

Effects of obesity induced by high-fat diet on the pharmacokinetics of cyclosporine A in rats

Yukako Ito, K. Takada, K. Fukushima, 2011 .

Protection against dextran sulfate sodium-induced colitis by microspheres of ellagic acid in rats.

Y. Jeong, K. Takeuchi, N. Shibata, 2002, Life sciences.

Application of Eudragit P‐4135F for the delivery of ellagic acid to the rat lower small intestine

Y. Jeong, K. Takeuchi, N. Shibata, 2001, The Journal of pharmacy and pharmacology.

Improvement of Large Intestinal Absorption of Insulin by Chemical Modification with Palmitic Acid in Rats

A. Yamamoto, K. Takada, S. Muranishi, 1992, The Journal of pharmacy and pharmacology.

Improvement of Intestinal Absorption of Thyrotropin‐releasing Hormone by Chemical Modification with Lauric Acid

A. Yamamoto, K. Takada, S. Muranishi, 1992, The Journal of pharmacy and pharmacology.

Intestinal absorption of carboxyfluorescein entrapped in liposomes in comparison with its administration with lipid-surfactant mixed micelles.

K. Takada, S. Muranishi, H. Yoshikawa, 1984, Journal of pharmacobio-dynamics.

Relationship between excretion clearance of rhodamine 123 and P-glycoprotein (Pgp) expression induced by representative Pgp inducers.

Asako Nishimura, N. Shibata, Yukako Ito, 2006, Biological & pharmaceutical bulletin.

Enhancement of pulmonary absorption of fluorescein isothiocyanate-labelled dextran (FITC-dextran) by sodium glycocholate in rats.

K. Takada, M. Yamamoto, H. Nakae, 1980, Chemical & pharmaceutical bulletin.

A novel emulsifier, labrasol, enhances gastrointestinal absorption of gentamicin.

N. Shibata, K. Takada, R. Tawa, 2001, Life sciences.

A method to potentiate enteral absorption of interferon and selective delivery into lymphatics.

N. Naruse, K. Takada, S. Muranishi, 1984, Journal of pharmacobio-dynamics.

Drug interactions between HIV protease inhibitors based on physiologically-based pharmacokinetic model.

N. Shibata, K. Takada, Weihua Gao, 2002, Journal of pharmaceutical sciences.

Pharmacokinetics of cisplatin in analbuminemic rats

H. Wada, N. Shibata, O. Ike, 1999, Biopharmaceutics & drug disposition.

Biodistribution of Cyclosporin Encapsulated in Liposomes Modified with Bioadhesive Polymer

M. Miyazaki, K. Takada, Y. Yoshikawa, 1997, The Journal of pharmacy and pharmacology.

Lymphatic transport of cyclosporin A from the abdominal cavity

K. Takada, N. Katayama, Takeshi Houjou, 1994 .

Distribution characteristics of immunosuppressants FK506 and cyclosporin A in the blood compartment

A. Kiriyama, K. Takada, N. Katayama, 1993, Biopharmaceutics & drug disposition.

Determination of a novel potent immunosuppressant (FK-506) in rat serum and lymph by high-performance liquid chromatography with chemiluminescence detection.

K. Takada, H. Tanaka, M. Nishiyama, 1990, Journal of chromatography.

Self-dissolving micropile array chip as percutaneous delivery system of protein drug.

Yukako Ito, K. Takada, K. Fukushima, 2010, Biological & pharmaceutical bulletin.

Pharmacokinetics of 5-fluorouracil and increased hepatic dihydropyrimidine dehydrogenase activity levels in 1,2-dimethylhydrazine-induced colorectal cancer model rats

Yukako Ito, K. Takada, S. Kobuchi, 2012, European Journal of Drug Metabolism and Pharmacokinetics.

Evaluation of intestinal pressure-controlled colon delivery capsule containing caffeine as a model drug in human volunteers.

K. Takada, Y. Yoshikawa, T. Shimokawa, 1998, Journal of controlled release : official journal of the Controlled Release Society.

Effect of Oleic Acid Vesicles on Intestinal Absorption of Carboxyfluorescein in Rats

K. Takada, S. Muranishi, H. Yoshikawa, 1986, Pharmaceutical Research.

Application of dissolving microneedles to glucose monitoring through dermal interstitial fluid.

T. Sakaeda, S. Morita, Yukako Ito, 2014, Biological & pharmaceutical bulletin.

Highly sensitive quantification of vancomycin in plasma samples using liquid chromatography-tandem mass spectrometry and oral bioavailability in rats.

N. Shibata, K. Takada, M. Ishida, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Permeability characteristics of endocrine-disrupting chemicals using an in vitro cell culture model, Caco-2 cells.

N. Shibata, K. Takada, Y. Yoshikawa, 2002, Current drug metabolism.

Determination of a novel 5-fluorouracil derivative in rat and human plasma by high-performance liquid chromatography.

K. Takada, S. Muranishi, H. Yoshikawa, 1982, Journal of chromatography.

Molecular weight dependence of permselectivity to rat small intestinal blood-lymph barrier for exogenous macromolecules absorbed from lumen.

K. Takada, S. Muranishi, H. Yoshikawa, 1984, Journal of pharmacobio-dynamics.

Pharmacokinetics and distribution of fluvoxamine to the brain in rats under oxidative stress

Yukako Ito, K. Takada, K. Fukushima, 2012, Free radical research.

Further mechanistic study on intestinal absorption enhanced by unsaturated fatty acids: reversible effect by sulfhydryl modification.

K. Takada, S. Muranishi, M. Murakami, 1992, Biochimica et biophysica acta.

Effect of water intake on pharmacokinetics of lansoprazole from fast disintegrating tablet in human subjects.

N. Shibata, Yukako Ito, K. Takada, 2004, Drug metabolism and pharmacokinetics.

Comparison of disappearance from blood and lymphatic delivery of human fibroblast interferon in rat by different administration routes.

N. Naruse, K. Takada, S. Muranishi, 1985, Journal of pharmacobio-dynamics.

Biological and pharmaceutical factors affecting the absorption and lymphatic delivery of ciclosporin A from gastrointestinal tract.

K. Takada, S. Muranishi, H. Yoshikawa, 1988, Journal of pharmacobio-dynamics.

Percutaneous absorption of interferon-α by self-dissolving micropiles

Yukako Ito, K. Takada, Atsushi Saeki, 2008 .

Effect of streptozotocin‐induced diabetes mellitus on the pharmacokinetics of nelfinavir in rats

Yukako Ito, K. Takada, K. Fukushima, 2008, Biopharmaceutics & drug disposition.

Distribution kinetics of FK‐506, a novel immunosuppressant, after intravenous administration to rats in comparison with cyclosporin A

K. Takada, Hisato Usuda, Mamoru Oh‐Hashi, 1992, Biopharmaceutics & drug disposition.

Selective transfer of 1-hexylcarbamoyl-5-fluorouracil into lymphatics by combination of β-cyclodextrin polymer complexation and absorption promoter in the rat

K. Uekama, K. Takada, S. Muranishi, 1985 .

Preparation and evaluation of once-a-day injectable microspheres of interferon alpha in rats.

K. Takada, Y. Yoshikawa, H. Yoshikawa, 1999, Journal of drug targeting.

Estimation of minimum whole-blood tacrolimus concentration for therapeutic drug monitoring with plasma prednisolone concentration: A retrospective cohort study in Japanese kidney transplant recipients.

N. Shibata, Yukako Ito, K. Takada, 2006, Current therapeutic research, clinical and experimental.

Semi-physiological pharmacokinetic–pharmacodynamic modeling and simulation of 5-fluorouracil for the whole time course of alterations in leukocyte, neutrophil and lymphocyte counts in rats

Asako Nishimura, N. Shibata, T. Hayakawa, 2014, Xenobiotica; the fate of foreign compounds in biological systems.

Pharmacokinetic/pharmacodynamic modeling of 5-fluorouracil by using a biomarker to predict tumor growth in a rat model of colorectal cancer.

Yukako Ito, K. Takada, S. Kobuchi, 2013, Journal of pharmaceutical sciences.

Synthesis of Palmitoyl Derivatives of Insulin and Their Biological Activities

Y. Kiso, K. Takada, S. Muranishi, 1989, Pharmaceutical Research.

Effect of food intake on the delivery of fluorescein as a model drug in colon delivery capsule after oral administration to beagle dogs.

K. Takada, Y. Yoshikawa, K. Matsuda, 1996, Journal of drug targeting.

Pharmacokinetic and pharmacodynamic studies following oral administration of erythropoietin mucoadhesive tablets to beagle dogs.

N. Shibata, N. Venkatesan, J. Yoshimitsu, 2006, International journal of pharmaceutics.

Application of pressure‐controlled colon delivery capsule to oral administration of glycyrrhizin in dogs

N. Shibata, K. Takada, Y. Yoshikawa, 2001, The Journal of pharmacy and pharmacology.

[Ulcerative colitis--colon delivery of 5-aminosalicylic acid].

K. Takada, G. Kimura, M. Muraoka, 1998, Nihon rinsho. Japanese journal of clinical medicine.

Importance of dissolution process on systemic availability of drugs delivered by colon delivery system.

K. Takada, Y. Yoshikawa, H. Yoshikawa, 1998, Journal of controlled release : official journal of the Controlled Release Society.

Preparation and evaluation of a time-controlled release capsule made of ethylcellulose for colon delivery of drugs.

T. Morimoto, K. Takada, T. Takaya, 1995, Journal of drug targeting.

Lipophilic Peptides: Synthesis of Lauroyl Thyrotropin-Releasing Hormone and Its Biological Activity

Y. Kiso, K. Takada, Keigo Yamada, 1991, Pharmaceutical Research.

Two-Layered Dissolving Microneedles for Percutaneous Delivery of Peptide/Protein Drugs in Rats

Keizo Fukushima, Kanji Takada, Hiromi Morita, 2010, Pharmaceutical Research.

Pharmaceutical approach to HIV protease inhibitor atazanavir for bioavailability enhancement based on solid dispersion system.

N. Shibata, Yukako Ito, K. Takada, 2007, Biological & pharmaceutical bulletin.

Incidence of low bioavailability of leuprolide acetate after percutaneous administration to rats by dissolving microneedles.

Yukako Ito, K. Takada, K. Fukushima, 2011, International journal of pharmaceutics.

Effect of plasma uric acid on pharmacokinetics of cyclosporine A in living‐related renal transplant recipients and pharmacokinetic study in rats with experimental hyperuricaemia

K. Takada, N. Yoshimura, M. Okamoto, 2009, Journal of clinical pharmacy and therapeutics.

Reduced elimination clearance of micafungin in rats with cholestatic hyperbilirubinemia

N. Shibata, K. Takada, K. Fukushima, 2009, Fundamental & clinical pharmacology.

Pharmacodynamic-pharmacokinetic profiles of metformin hydrochloride from a mucoadhesive formulation of a polysaccharide with antidiabetic property in streptozotocin-induced diabetic rat models.

M. Adikwu, K. Takada, Y. Yoshikawa, 2004, Biomaterials.

Long-term pharmacokinetic efficacy and safety of low-dose ritonavir as a booster and atazanavir pharmaceutical formulation based on solid dispersion system in rats.

Yukako Ito, K. Takada, K. Fukushima, 2008, Biological & pharmaceutical bulletin.

Enhancing mechanism of Labrasol on intestinal membrane permeability of the hydrophilic drug gentamicin sulfate.

N. Shibata, Yukako Ito, K. Takada, 2006, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Bioadhesive delivery of metformin using prosopis gum with antidiabetic potential.

M. Adikwu, K. Takada, Y. Yoshikawa, 2003, Biological & pharmaceutical bulletin.

Nanoporous and Nanosize Materials for Drug Delivery Systems

H. Takeuchi, K. Takada, Y. Fukumori, 2007 .

Therapeutic Drug Monitoring of Vancomycin in Dermal Interstitial Fluid Using Dissolving Microneedles

T. Sakaeda, Yukako Ito, K. Takada, 2016, International journal of medical sciences.

Self-dissolving micropile array tips for percutaneous administration of insulin

Yukako Ito, K. Takada, N. Sugioka, 2010, Journal of materials science. Materials in medicine.

Transport of Azithromycin into Extravascular Space in Rats

A. Kuwahara, T. Sakaeda, Yukako Ito, 2016, Antimicrobial Agents and Chemotherapy.

Recovery Rate of Rat Skin Micropores Made by Dissolving Microneedles

N. Miyamoto, Yukako Ito, K. Takada, 2013 .

Two- and Three-Layered Dissolving Microneedles for Transcutaneous Delivery of Model Vaccine Antigen in Rats

Yukako Ito, K. Takada, S. Naito, 2012 .

Evaluation of self-dissolving needles containing low molecular weight heparin (LMWH) in rats.

Yukako Ito, K. Takada, N. Sugioka, 2008, International journal of pharmaceutics.

Feasibility of microneedles for percutaneous absorption of insulin.

Kanji Takada, Atsushi Saeki, Yukako Ito, 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Self-dissolving microneedles for the percutaneous absorption of EPO in mice

J. Yoshimitsu, Yukako Ito, K. Takada, 2006, Journal of drug targeting.

Effect of adsorbents on the absorption of lansoprazole with surfactant.

N. Shibata, Yukako Ito, K. Takada, 2005, International journal of pharmaceutics.

Biopharmaceutical study of the hepato-biliary transport of drugs. I. Hepato-biliary transport of non-metabolizing organic anionic compounds in rat.

K. Takada, S. Muranishi, Y. Mizobuchi, 1974, Chemical & pharmaceutical bulletin.

Dissolving microneedles to obtain rapid local anesthetic effect of lidocaine at skin tissue

Yukako Ito, K. Takada, Kazuki Imada, 2013, Journal of drug targeting.

Two-layered dissolving microneedles for percutaneous delivery of sumatriptan in rats

Yukako Ito, K. Takada, K. Fukushima, 2011, Drug development and industrial pharmacy.

Permeation enhancement of ascorbic acid by self-dissolving micropile array tip through rat skin.

Yukako Ito, K. Takada, K. Fukushima, 2010, Chemical & pharmaceutical bulletin.

Pharmacokinetic study on saturated hepato-biliary transport of acetyl procainamide ethobromide.

K. Takada, S. Muranishi, H. Nakae, 1981, Journal of pharmacobio-dynamics.

Transport rates of hepatic uptake and biliary excretion of an organic cation, acetyl procainamide ethobromide.

K. Takada, S. Muranishi, H. Nakae, 1980, Biochemical pharmacology.

Absorption of interferon alpha from patches in rats

N. Shibata, T. Kishida, T. Kishida, 2005, Journal of drug targeting.

Studies on the intestinal absorption of low molecular weight heparin using saturated fatty acids and their derivatives as an absorption enhancer in rats.

K. Takada, Saori Mori, A. Matsuura, 2004, Biological & pharmaceutical bulletin.

In situ intestinal absorption studies on low molecular weight heparin in rats using labrasol as absorption enhancer.

Kanji Takada, Saori Mori, Yukako Yoshikawa, 2004, International journal of pharmaceutics.

Possibility of a patch system as a new oral delivery system.

N. Shibata, K. Takada, Y. Yoshikawa, 2003, International journal of pharmaceutics.

Evaluation of gastrointestinal transit characteristics of oral patch preparation using caffeine as a model drug in human volunteers.

N. Shibata, K. Takada, Y. Yoshikawa, 2002, Drug metabolism and pharmacokinetics.

Retention and transit of intestinal mucoadhesive films in rat small intestine.

K Takada, N. Shibata, K. Takada, 2001, International journal of pharmaceutics.

Development and Evaluation of Noncompartmental Pharmacokinetic Analysis Program “WinHARMONY” Using Visual BASIC Language Having a Function of an Automatic Recognition of Terminal Elimination Phase of Plasma Drug Concentration vs. Time Profile

Kanji Takada, Kazuo Kato, Yukako Yoshikawa, 1998 .

In vitro anti-human immunodeficiency virus (HIV) activities of transition state mimetic HIV protease inhibitors containing allophenylnorstatine

S. Gulnik, J. Erickson, M. Nomizu, 1993, Antimicrobial Agents and Chemotherapy.

Enhanced intestinal absorption of vancomycin with Labrasol and D-alpha-tocopheryl PEG 1000 succinate in rats.

Kanji Takada, Makoto Ishida, Yukako Yoshikawa, 2003, International journal of pharmaceutics.

Absorption Enhancing Effect of Labrasol on the Intestinal Absorption of Insulin in Rats

N. Shibata, K. Takada, Y. Yoshikawa, 2002, Journal of drug targeting.

Oral delivery of hematopoietic factors

K. Takada, 2006 .

Application of a Biomagnetic Measurement System (BMS) to the Evaluation of Gastrointestinal Transit of Intestinal Pressure-Controlled Colon Delivery Capsules (PCDCs) in Human Subjects

N. Shibata, K. Takada, A. Arakawa, 2000, Pharmaceutical Research.

Colon Delivery Efficiencies of Intestinal Pressure‐controlled Colon Delivery Capsules Prepared by a Coating Machine in Human Subjects

K. Takada, Y. Yoshikawa, T. Shimokawa, 2000, The Journal of pharmacy and pharmacology.

Development of a Colon Delivery Capsule and the Pharmacological Activity of Recombinant Human Granulocyte Colony‐stimulating Factor (rhG‐CSF) in Beagle Dogs

K. Takada, T. Takaya, K. Niwa, 1995, The Journal of pharmacy and pharmacology.

Is recombinant human granulocyte colony-stimulating factor (G-CSF) orally available in rats?

K. Takada, S. Muranishi, A. Shimosaka, 1989, Chemical & pharmaceutical bulletin.

Targeted and sustained delivery of aclarubicin to lymphatics by lactic acid-oligomer microsphere in rat.

Y. Ikada, Y. Tabata, S. Hyon, 1989, Chemical & pharmaceutical bulletin.

Time-dependent interaction of ritonavir in chronic use: the power balance between inhibition and induction of P-glycoprotein and cytochrome P450 3A.

K. Takada, H. Aoyama, K. Fukushima, 2013, Journal of pharmaceutical sciences.

Preparation and evaluation of oral solid heparin using emulsifier and adsorbent for in vitro and in vivo studies.

N. Shibata, Yukako Ito, K. Takada, 2006, International journal of pharmaceutics.

Determination of a new immunosuppressant, mycophenolate mofetil, and its active metabolite, mycophenolic acid, in rat and human body fluids by high-performance liquid chromatography.

K. Takada, N. Sugioka, T. Ohta, 1994, Journal of chromatography. B, Biomedical applications.

Pharmacokinetics of mycophenolate mofetil, a new immunosuppressant, in rats.

K. Takada, N. Sugioka, H. Koyama, 1996, Journal of pharmaceutical sciences.

Stability and pharmacokinetic studies of a new immunosuppressant, mycophenolate mofetil (RS‐61443), in rats

K. Takada, T. Yasumura, Hikaru Koyama, 1995, Biopharmaceutics & drug disposition.

Effect of absorption enhancers on pulmonary absorption of fluorescein isothiocyanate dextrans with various molecular weights

A. Yamamoto, K. Takada, S. Muranishi, 1991 .

Promoting effect of Azone on intestinal absorption of poorly absorbable drugs in rats

K. Takada, S. Muranishi, M. Murakami, 1986 .

Method to increase the systemically delivered amount of drug from dissolving microneedles.

N. Miyamoto, Yukako Ito, K. Takada, 2013, Chemical & pharmaceutical bulletin.

Effect of chronic administration of ritonavir on function of cytochrome P450 3A and P-glycoprotein in rats.

N. Shibata, Yukako Ito, K. Takada, 2005, Biological & pharmaceutical bulletin.

Oral solid gentamicin preparation using emulsifier and adsorbent.

Kanji Takada, Makoto Ishida, N. Shibata, 2005, Journal of controlled release : official journal of the Controlled Release Society.

New preparation method of intestinal pressure-controlled colon delivery capsules by coating machine and evaluation in beagle dogs.

K. Takada, Y. Yoshikawa, T. Shimokawa, 1998, Journal of controlled release : official journal of the Controlled Release Society.

Effect of indinavir on the intestinal exsorption of amprenavir, saquinavir and nelfinavir after intravenous administration in rats.

Asako Nishimura, N. Shibata, K. Takada, 2003, Biological & pharmaceutical bulletin.

Implantable slow release cyclosporin A (CYA) delivery system to thoracic lymph duct

K. Takada, Y. Ohno, Rika Tanaka, 1995 .

Nano-sized water-in-oil-in-water emulsion enhances intestinal absorption of calcein, a high solubility and low permeability compound.

K. Takada, K. Koga, Nobuo Takarada, 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Pharmacokinetic and pharmacodynamic evaluation of insulin dissolving microneedles in dogs.

Yukako Ito, K. Takada, K. Fukushima, 2010, Diabetes technology & therapeutics.

Oral Sustained‐release Cisplatin Capsule

O. Ike, K. Takada, Y. Yoshikawa, 1996, The Journal of pharmacy and pharmacology.

Effect of Salicylate on the Uptake of Cefmetazole into Brain of Mice

N. Naruse, K. Takada, S. Muranishi, 1985, Pharmaceutical Research.

Pharmacological effect of recombinant human colony-stimulating factor (rhG-CSF) after administration into rat large intestine

K. Takada, T. Takaya, K. Niwa, 1994 .

Biopharmaceutical study of the hepato-biliary transport of drugs. II. Roles of the liver cytoplasmic Y and Z binding proteins and T binder on the hepato-biliary transport of organic anionic compounds.

K. Takada, S. Muranishi, M. Ueda, 1974, Chemical & pharmaceutical bulletin.

Utility of nano-sized, water-in-oil emulsion as a sustained release formulation of glycyrrhizin.

K. Takada, K. Matsuno, H. Ueta, 2011, Biological & pharmaceutical bulletin.

Pharmacokinetics of glycyrrhizin in normal and albumin‐deficient rats

K. Takada, K. Koga, Kazuo Ohyanagi, 2008, Biopharmaceutics & drug disposition.

Characteristics of intestinal absorption and disposition of glycyrrhizin in mice

N. Shibata, K. Takada, Y. Yoshikawa, 2000, Biopharmaceutics & drug disposition.

Application of a colon delivery capsule to 5-aminosalicylic acid and evaluation of the pharmacokinetic profile after oral administration to beagle dogs.

K. Takada, H. Suzuki, K. Sawada, 1997, Journal of drug targeting.

Characterization of norfloxacine release from tablet coated with a new pH-sensitive polymer, P-4135F.

K. Takada, Y. Yoshikawa, T. Ohno, 1999, Journal of drug targeting.

Technology to obtain sustained release characteristics of drugs after delivered to the colon.

K. Takada, Y. Yoshikawa, T. Shimokawa, 1999, Journal of drug targeting.

Pharmacokinetic characterization of a human immunodeficiency virus protease inhibitor, saquinavir, during ethanol intake in rats

N. Shibata, T. Shirasaka, K. Takada, 2003, Biopharmaceutics & drug disposition.

Metabolic Characterization of a Tripeptide Human Immunodeficiency Virus Type 1 Protease Inhibitor, KNI-272, in Rat Liver Microsomes

A. Kiriyama, K. Takada, T. Nishiura, 1999, Antimicrobial Agents and Chemotherapy.

Microsomes Protease Inhibitor , KNI-272 , in Rat Liver Human Immunodeficiency Virus Type 1 Metabolic Characterization of a Tripeptide

A. Kiriyama, K. Takada, T. Nishiura, 1999 .

Absorption of new HIV‐1 protease inhibitor, KNI‐272, after intraduodenal and intragastric administrations to rats: Effect of solvent

A. Kiriyama, Y. Kiso, K. Takada, 1995, Biopharmaceutics & drug disposition.

Plasma pharmacokinetics and urinary and biliary excretion of a new potent tripeptide HIV‐1 protease inhibitor, KNI‐272, in rats after intravenous administration

A. Kiriyama, Y. Kiso, K. Takada, 1994, Biopharmaceutics & drug disposition.

Comparison of a new orally potent tripeptide HIV‐1 protease inhibitor (anti‐aids drug) based on pharmacokinetic characteristics in rats after intravenous and intraduodenal administrations

A. Kiriyama, Y. Kiso, K. Takada, 1993, Biopharmaceutics & drug disposition.

Pharmacokinetic study of a tripeptide HIV‐1 protease inhibitor, KNI‐174, in rats after intravenous and intraduodenal administrations

A. Kiriyama, Y. Kiso, K. Takada, 1993, Biopharmaceutics & drug disposition.

Evaluation of factors to decrease plasma concentration of an HIV protease inhibitor, saquinavir in ethanol-treated rats.

N. Shibata, K. Takada, Y. Yoshikawa, 2004, Biological & pharmaceutical bulletin.

Sensitive and simultaneous determination of HIV protease inhibitors in rat biological samples by liquid chromatography-mass spectrometry.

N. Shibata, K. Takada, Weihua Gao, 2002, Biomedical chromatography : BMC.

In‐vitro and in‐vivo pharmacokinetic interactions of amprenavir, an HIV protease inhibitor, with other current HIV protease inhibitors in rats

N. Shibata, K. Takada, Weihua Gao, 2002, The Journal of pharmacy and pharmacology.

Pharmacokinetic Interactions between HIV‐1 Protease Inhibitors in Rats: Study on Combinations of Two Kinds of HIV‐1 Protease Inhibitors

N. Shibata, K. Takada, H. Okamoto, 2000, The Journal of pharmacy and pharmacology.

Pharmacokinetic and pharmacodynamic studies following percutaneous absorption of erythropoietin micropiles to rats.

J. Yoshimitsu, K. Takada, N. Sugioka, 2007, Journal of controlled release : official journal of the Controlled Release Society.

cAMP stimulates human immunodeficiency virus (HIV-1) from latently infected cells of monocyte-macrophage lineage: synergism with TNF-alpha.

N. Yamamoto, O. Hazeki, Y. Koyanagi, 1993, Virology.

The mode of enhanced enteral absorption of macromolecules by lipid-surfactant mixed micelles. I.

K. Takada, S. Muranishi, H. Yoshikawa, 1986, Journal of pharmacobio-dynamics.

Evaluation of insulin self-dissolving micropiles by PK/PD analysis

H. Nakane, Yukako Ito, K. Takada, 2010 .

Self-dissolving micropiles for the percutaneous absorption of recombinant human growth hormone in rats.

Yukako Ito, K. Takada, N. Sugioka, 2008, Biological & pharmaceutical bulletin.

Antihyperglycemic effect of insulin from self-dissolving micropiles in dogs.

Yukako Ito, K. Takada, Atsushi Saeki, 2008, Chemical & pharmaceutical bulletin.

Development of Interferon Suppositories. I. Enhanced Rectal Absorption of Human Fibroblast Interferon by Fusogenic Lipid via Lymphotropic Delivery in Rats

N. Naruse, K. Takada, S. Muranishi, 1986, Pharmaceutical Research.

Potentiation of Enteral Absorption of Human Interferon Alpha and Selective Transfer into Lymphatics in Rats

N. Naruse, K. Takada, S. Muranishi, 1985, Pharmaceutical Research.

Intestinal absorption enhanced by unsaturated fatty acids: inhibitory effect of sulfhydryl modifiers.

K. Takada, S. Muranishi, M. Murakami, 1988, Biochimica et biophysica acta.

Combinative promotion effect of azone and fusogenic fatty acid on the large intestinal absorption in rat

H. Fukui, K. Takada, S. Muranishi, 1986 .

Enhanced Absorption and Lymphatic Transport of Macromolecules via the Rectal Route

K. Takada, S. Muranishi, H. Yoshikawa, 1986 .

Potentiation of antitumor effect of bleomycin by lipid-surfactant mixed micelles. I. In vivo and tumor-neutralizing activity against mouse Ehrlich ascites tumor and rat ascites hepatoma AH66.

K. Takada, S. Muranishi, H. Yoshikawa, 1985, Journal of pharmacobio-dynamics.

Enhancing effect of absorption promoters on percutaneous absorption of a model dye (6-carboxyfluorescein) as poorly absorbable drugs. I. Comparison of plasma levels after addition of various absorption promoters in rat.

K. Takada, S. Muranishi, T. Ohshima, 1984, Journal of pharmacobio-dynamics.

DDS with MFGM(milk fat globule membrane): preparation of fat emulsions and emulsifiability of MFGM.

K. Takada, S. Muranishi, T. Moriwaki, 1990 .

Evaluation of fast disintegrating lansoprazole tablet in human subjects.

N. Shibata, K. Takada, S. Irie, 2004, Drug metabolism and pharmacokinetics.

Usefulness of Basic Fibroblast Growth Factor (bFGF) Loaded Dissolving Microneedles for Local Therapy of Skin Wounds

I. Ono, Y. Akasaka, Yukako Ito, 2013 .

[Novel formulations of a liver protection drug glycyrrhizin].

N. Shibata, S. Kawashima, K. Takada, 2007, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Evaluation of oral formulations of gentamicin containing labrasol in beagle dogs.

Kanji Takada, Makoto Ishida, Yukako Yoshikawa, 2003, International journal of pharmaceutics.

Preparation and rectal absorption of highly concentrated glycyrrhizin solution.

N. Shibata, S. Kawashima, K. Takada, 2003, Biological & pharmaceutical bulletin.

Determination of 18α-glycyrrhizin and 18β-glycyrrhizin in dog plasma by high-performance liquid chromatography

S. Kawashima, K. Takada, K. Ohmachi, 2000 .

A simple preparation method for dispersing glycyrrhizin solution into oil phase using an evaporation technique

K. Takada, K. Koga, H. Liu, 2009 .

Novel Formulations of a Liver Protection Drug Glycyrrhizin

N. Shibata, S. Kawashima, K. Takada, 2007 .

Comparative Study of Physicochemical Properties and Constituent Contents of Glycyrrhizin Injectable Solutions

K. Takada, K. Koga, Kazuo Ohyanagi, 2008 .

A novel preparation of concentrated glycyrrhizin solution by pretreatment with eugenol

S. Kawashima, K. Takada, M. Murakami, 2004 .

Effects of bile duct stricture on the pharmacokinetics of the immunosuppressant tacrolimus in rats

K. Takada, N. Yoshimura, K. Fukushima, 2013 .

Effect of oxidative stress on the pharmacokinetics of clomipramine in rats treated with ferric-nitrilotriacetate.

Yukako Ito, K. Takada, H. Aoyama, 2011, Drug metabolism letters.

[Pharmacokinetic study by gastrointestinal absorption of indomethacin polymorphs in the rabbit (author's transl)].

T. Yamamoto, K. Takada, K. Kuroda, 1982, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Pharmacokinetics of FK-506, a novel immunosuppressant, after intravenous and oral administrations to rats.

K. Takada, H. Tanaka, S. Muranishi, 1991, Journal of pharmacobio-dynamics.

Increased systemic availability of cyclosporin A by formulation design: pharmacokinetic consideration on its transport

K. Takada, T. Oka, S. Muranishi, 1988 .

Effect of administration route on the selective lymphatic delivery of cyclosporin A by lipid-surfactant mixed micelles.

N. Shibata, K. Takada, T. Oka, 1986, Journal of pharmacobio-dynamics.

Preparation and evaluation of micro‐porous ethylcellulose capsule as oral sustained‐release preparation of theophylline

A. Kawai, K. Takada, H. Yasui, 1998, Biopharmaceutics & drug disposition.

Promotion of the selective lymphatic delivery of cyclosporin A by lipid-surfactant mixed micelles.

N. Shibata, K. Takada, T. Oka, 1985, Journal of pharmacobio-dynamics.

Pharmacokinetics of 5-fluorouracil and increased hepatic dihydropyrimidine dehydrogenase activity levels in 1,2-dimethylhydrazine-induced colorectal cancer model rats

Yukako Ito, K. Takada, S. Kobuchi, 2013, European Journal of Drug Metabolism and Pharmacokinetics.

Biopharmaceutical study of the hepatobiliary transport of drugs. VI. Inhibition of active biliary excretion of organic cations by retrograde infusion.

K. Takada, H. Okamoto, S. Muranishi, 1977, Chemical & pharmaceutical bulletin.

Effect of serum lipids on the pharmacokinetics of atazanavir in hyperlipidemic rats.

K. Takada, H. Aoyama, K. Fukushima, 2009, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Pharmacokinetic interactions between HIV‐protease inhibitors in rats

Y. Matsumura, K. Takada, Y. Yoshikawa, 1999, Biopharmaceutics & drug disposition.

Effect of fiber length of carbon nanotubes on the absorption of erythropoietin from rat small intestine.

N. Venkatesan, Yukako Ito, K. Takada, 2007, International journal of pharmaceutics.

Pharmacokinetic analysis of plasma drug level data obtained from a transdermal therapeutic system with a complex absorption model

K. Takada, S. Muranishi, H. Yoshikawa, 1990 .

Pharmacokinetics of the hepatobiliary transport of bromphenol blue as a model of organic anionic compounds

K. Takada, S. Muranishi, H. Sezaki, 1974, Journal of Pharmacokinetics and Biopharmaceutics.

Enhanced Selective Lymphatic Delivery of Cyclosporin A by Solubilizers and Intensified Immunosuppressive Activity Against Mice Skin Allograft

K. Takada, T. Oka, S. Muranishi, 1986, Pharmaceutical Research.

Application of calcium thioglycolate to improve transdermal delivery of theophylline in rats.

K. Takada, S. Muranishi, T. Ohshima, 1984, Chemical & pharmaceutical bulletin.

Diethyl ether fraction of Labrasol having a stronger absorption enhancing effect on gentamicin than Labrasol itself.

Kanji Takada, Makoto Ishida, N. Shibata, 2002, International journal of pharmaceutics.

Effect of lipophilicity on the bioavailability of drugs after percutaneous administration by dissolving microneedles.

Yukako Ito, K. Takada, Tsutomu Tanaka, 2012, Journal of pharmaceutical sciences.

Prolonged hypoglycemic effects obtained by two-layered dissolving microneedles containing insulin glargine

T. Sakaeda, Yukako Ito, K. Takada, 2014 .

Percutaneous absorption of interferon-alpha by self-dissolving micropiles.

Yukako Ito, K. Takada, Atsushi Saeki, 2008, Journal of drug targeting.

Transdermal insulin application system with dissolving microneedles.

Yukako Ito, K. Takada, N. Yoshimoto, 2012, Diabetes technology & therapeutics.

A model independent approach to describe the blood disappearance profile of intravenously administered drugs.

K. Takada, S. Asada, 1981, Chemical & pharmaceutical bulletin.

Molecular weight dependence on bioavailability of FITC-dextran after administration of self-dissolving micropile to rat skin

Yukako Ito, K. Takada, N. Sugioka, 2010, Drug development and industrial pharmacy.

High percutaneous bioavailability of granisetron by dissolving microneedleswe

Yukako Ito, K. Takada, A. Ikejiri, 2012 .

Effect of plasma lipid on pharmacokinetics of ciclosporin and its relationship with plasma prednisolone level in renal transplant patients

N. Shibata, Yukako Ito, K. Takada, 2006, The Journal of pharmacy and pharmacology.

Enhancing effect of absorption promoters on percutaneous absorption of a model dye (6-carboxyfluorescein) as a poorly absorbable drug. III. Histological study after addition of various absorption promoters in rats.

K. Takada, S. Muranishi, T. Ohshima, 1986, Journal of Pharmacobio-Dynamics.

Oral Sustained‐release Cisplatin Preparation for Rats and Mice

H. Wada, O. Ike, K. Takada, 1997, The Journal of pharmacy and pharmacology.