Chun-ying Shu

发表

Aggregation studies of the water-soluble gadofullerene magnetic resonance imaging contrast agent: [Gd@C82O6(OH)16(NHCH2CH2COOH)8]x.

Chun-ying Shu, E. Zhang, Jun-feng Xiang, 2006, The journal of physical chemistry. B.

Synthesis and characterization of a new water-soluble endohedral metallofullerene for MRI contrast agents

Chunru Wang, L. Gan, Chun-ying Shu, 2006 .

Gadofullerene nanoparticles extend survival rate and down-regulate thrombin expression in orthotopic pancreatic cancer

Chunru Wang, Chun-ying Shu, Xue Li, 2021, Science China Materials.

Effects of fullerene derivatives on bioluminescence and application for protease detection.

Chunru Wang, Zhi-ping Zhang, Xian-En Zhang, 2012, Chemical communications.

Bipyridine conformations control the solid-state supramolecular chemistry of zinc(II) phthalocyanine with bipyridines

Hongwei Ma, C. Bai, Q. Zeng, 2005 .

Structural effect and mechanism of C70-carboxyfullerenes as efficient sensitizers against cancer cells.

Li Xu, X. Fang, Chunru Wang, 2012, Small.

Self-assembly of highly dispersed Pt and PtRu nanoparticles on perylene diimide derivatives functionalized carbon nanotubes as enhanced catalysts for methanol electro-oxidation

Chunru Wang, Li Jiang, Chun-ying Shu, 2013 .

RF-assisted gadofullerene nanoparticles induces rapid tumor vascular disruption by down-expression of tumor vascular endothelial cadherin.

Xia Li, Chunru Wang, Ying Zhang, 2018, Biomaterials.

Real-time monitoring of tumor vascular disruption induced by radiofrequency assisted gadofullerene

Xue Li, Chunru Wang, Chun-ying Shu, 2018, Science China Materials.

Formation of nitrogen-doped mesoporous graphitic carbon with the help of melamine.

A. Cao, Jiechao Ge, Chunru Wang, 2014, ACS applied materials & interfaces.

Gadolinium(III) Porpholactones as Efficient and Robust Singlet Oxygen Photosensitizers.

Juan Tang, Kunhui Liu, Hongmei Su, 2016, Chemistry.

pH-responsive mechanism of a deoxycholic acid and folate comodified chitosan micelle under cancerous environment.

L. Wan, Chun-ying Shu, Daiqin Chen, 2013, The journal of physical chemistry. B.

Multifunctional upconversion–nanoparticles–trismethylpyridylporphyrin–fullerene nanocomposite: a near-infrared light-triggered theranostic platform for imaging-guided photodynamic therapy

Chun-Hua Yan, Pengfei Wang, Jiechao Ge, 2015 .

Enhanced photodynamic efficiency of an aptamer-guided fullerene photosensitizer toward tumor cells.

Li Xu, X. Fang, Chunru Wang, 2013, Chemistry, an Asian journal.

A Versatile and Clearable Nanocarbon Theranostic Based on Carbon Dots and Gadolinium Metallofullerene Nanocrystals

Pengfei Wang, Jiechao Ge, Chunru Wang, 2016, Advanced healthcare materials.

In situ growth of gold nanoparticles on hydrogen-bond supramolecular structures with high peroxidase-like activity at neutral pH and their application to one-pot blood glucose sensing

Jiechao Ge, Chunru Wang, Chun-ying Shu, 2017 .

Fullerene nanoparticles: a promising candidate for the alleviation of silicosis-associated pulmonary inflammation.

Chunru Wang, Chun-ying Shu, Xue Li, 2020, Nanoscale.

Facile preparation of a new gadofullerene-based magnetic resonance imaging contrast agent with high 1H relaxivity.

W. Xu, Zhijian Chen, P. Fatouros, 2009, Bioconjugate chemistry.

The effect of hemiketals on the relaxivity of endohedral gadofullerenols

Chunru Wang, Chun-ying Shu, Ruimin Li, 2015 .

Radioactive lutetium metallofullerene 177LuxLu(3-x)N@C80-PCBPEG derivative: a potential tumor-targeted theranostic agent.

Shunzhong Luo, Chunru Wang, Chun-ying Shu, 2015, Journal of materials chemistry. B.

Tunable tribological properties in water-based lubrication of water-soluble fullerene derivatives via varying terminal groups

Xinchun Lu, Yuhong Liu, Chun-ying Shu, 2012 .

Photo-triggered gadofullerene: enhanced cancer therapy by combining tumor vascular disruption and stimulation of anti-tumor immune responses.

Jiechao Ge, Chunru Wang, Chun-ying Shu, 2019, Biomaterials.

C70-carboxyfullerenes as efficient antioxidants to protect cells against oxidative-induced stress.

X. Fang, Chunru Wang, Chun-ying Shu, 2013, ACS applied materials & interfaces.

Multifunctional gadofulleride nanoprobe for magnetic resonance imaging/fluorescent dual modality molecular imaging and free radical scavenging

Jiechao Ge, Chunru Wang, Hisham A Alhadlaq, 2013 .

Protective effect of C70-carboxyfullerene against oxidative-induced stress on postmitotic muscle cells.

X. Fang, Chunru Wang, Chun-ying Shu, 2013, ACS applied materials & interfaces.

Fullerene-induced increase of glycosyl residue on living plant cell wall.

Jinxing Lin, Yuanyuan Zhao, X. Fang, 2013, Environmental science & technology.

Addition of carbene to the equator of C(70) to produce the most stable C(71)H(2) isomer: 2 aH-2(12)a-homo(C(70)-D(5h(6)))[5,6]fullerene.

Chunru Wang, Taishan Wang, Li Jiang, 2010, Angewandte Chemie.

A novel glucose colorimetric sensor based on intrinsic peroxidase-like activity of C60-carboxyfullerenes.

Jiechao Ge, Chunru Wang, Chun-ying Shu, 2013, Biosensors & bioelectronics.

A water-soluble gadolinium metallofullerenol: facile preparation, magnetic properties and magnetic resonance imaging application.

Chunru Wang, Taishan Wang, Li Jiang, 2016, Dalton transactions.

Designing an Amino-Fullerene Derivative C70-(EDA)8 to Fight Superbacteria.

Chunru Wang, Libing Liu, Shu Wang, 2019, ACS applied materials & interfaces.

Multifunctional nanoprobe for MRI/optical dual-modality imaging and radical scavenging.

Fabao Gao, I. Pyykkö, Chunru Wang, 2013, Chemistry.

Eco-friendly synthesis of size-controllable amine-functionalized graphene quantum dots with antimycoplasma properties.

Chunru Wang, Yucheng Wang, Ying Gu, 2013, Nanoscale.

Conjugation of functionalized gadolinium metallofullerenes with IL-13 peptides for targeting and imaging glial tumors.

P. Fatouros, Jiechao Ge, W. Broaddus, 2011, Nanomedicine.

Improving the photo current of the [60]PCBM/P3HT photodetector device by using wavelength-matched photonic crystals

Jingxia Wang, Yanlin Song, W. Xu, 2014 .

Ultrasmall Pd/Au bimetallic nanocrystals embedded in hydrogen-bonded supramolecular structures: facile synthesis and catalytic activities in the reduction of 4-nitrophenol

A. Cao, Chunru Wang, W. Xu, 2015 .

Dual regulation on oxidative stress and endoplasmic reticulum stress by [70] fullerenes for reversing insulin resistance in diabetes

Chunru Wang, Lei Liu, Chun-ying Shu, 2022, Nano Today.

Dihydronaphthyl-based [60]fullerene bisadducts for efficient and stable polymer solar cells.

Yongfang Li, Chunru Wang, Zhishan Bo, 2012, Chemical communications.

Gadofullerene Nanoparticles Reverse Dysfunctions of Pancreas and Improve Hepatic Insulin Resistance for Type 2 Diabetes Mellitus Treatment.

Xue Li, Yingjie Wu, Chunru Wang, 2019, ACS nano.

Enhanced electrocatalytic performance for methanol oxidation of Pt nanoparticles on Mn3O4-modified multi-walled carbon nanotubes

Chunru Wang, Taishan Wang, Li Jiang, 2012 .

Preparation of Pd-decorated fullerenols on carbon nanotubes with excellent electrocatalytic properties in alkaline media

Chunru Wang, Li Jiang, Chun-ying Shu, 2013 .

Synergistic Effect of Human Serum Albumin and Fullerene on Gd-DO3A for Tumor-Targeting Imaging.

Chunru Wang, Chun-ying Shu, Mingming Zhen, 2016, ACS applied materials & interfaces.

Maximizing the relaxivity of Gd-complex by synergistic effect of HSA and carboxylfullerene.

L. Ye, Chunru Wang, Chan Jin, 2012, ACS applied materials & interfaces.

The positive influence of fullerene derivatives bonded to manganese(III) porphyrins on water proton relaxation.

Chunru Wang, Chun-ying Shu, Ruimin Li, 2015, Dalton transactions.

Multifunctional imaging probe based on gadofulleride nanoplatform.

Chunru Wang, Chan Jin, Yong-Ji Yang, 2012, Nanoscale.

Size-tunable NaGdF4 nanoparticles as T2 contrast agents for high-field magnetic resonance imaging

Xue Li, Chunru Wang, Chun-ying Shu, 2017 .

Inhalable gadofullerenol/[70] fullerenol as high-efficiency ROS scavengers for pulmonary fibrosis therapy.

Chunru Wang, Chun-ying Shu, Mingming Zhen, 2018, Nanomedicine : nanotechnology, biology, and medicine.

Susceptible electron spin adhering to an yttrium cluster inside an azafullerene C79N.

Chunru Wang, Taishan Wang, Li Jiang, 2012, Chemical communications.

Spin divergence induced by exohedral modification: ESR study of Sc3C2@C80 fulleropyrrolidine.

W. Xu, Chunru Wang, Taishan Wang, 2010, Angewandte Chemie.

Recent Progress of Molecular Imaging Probes Based on Gadofullerenes

Chunru Wang, Chun-ying Shu, Mingming Zhen, 2012 .

Preparation and ESR study of Sc3C2@C80 bis-addition fulleropyrrolidines.

Chunru Wang, Taishan Wang, Li Jiang, 2012, Dalton transactions.

Entrapped Planar Trimetallic Carbide in a Fullerene Cage: Synthesis, Isolation, and Spectroscopic Studies of Lu3C2@C88

W. Xu, Chunru Wang, Taishan Wang, 2011 .

Organophosphonate Functionalized Gd@C 82 as a Magnetic Resonance Imaging Contrast Agent

P. Fatouros, Chunru Wang, H. Gibson, 2008 .

Conjugation of a water-soluble gadolinium endohedral fulleride with an antibody as a magnetic resonance imaging contrast agent.

P. Fatouros, H. Gibson, F. Corwin, 2008, Bioconjugate chemistry.

Comparative Spectroscopic and Reactivity Studies of Sc3-xYxN@C80 (x = 0−3)

Chunru Wang, L. Fan, Chun-ying Shu, 2007 .

Encapsulation of a radiolabeled cluster inside a fullerene cage, (177)Lu(x)Lu((3-x))N@C(80): an interleukin-13-conjugated radiolabeled metallofullerene platform.

P. Fatouros, Jiechao Ge, H. Gibson, 2010, Journal of the American Chemical Society.

Protein Conformation Changes Induced by a Novel Organophosphate-Containing Water-Soluble Derivative of a C60 Fullerene Nanoparticle

Yalin Tang, Chunru Wang, Chun-ying Shu, 2007 .

G-quadruplex DNAzymes-induced highly selective and sensitive colorimetric sensing of free heme in rat brain.

Jiechao Ge, Chunru Wang, Qin Jiang, 2014, The Analyst.

Biocompatible [60]/[70] Fullerenols: Potent Defense against Oxidative Injury Induced by Reduplicative Chemotherapy.

Chunru Wang, Liping Wang, Li Jiang, 2017, ACS applied materials & interfaces.

C64H4: production, isolation, and structural characterizations of a stable unconventional fulleride.

L. Wan, H. Shinohara, Chun-ying Shu, 2006, Journal of the American Chemical Society.

Gd@C82-(ethylenediamine)8 Nanoparticle: A New High-Efficiency Water-Soluble ROS Scavenger.

Chunru Wang, Taishan Wang, Chun-ying Shu, 2016, ACS applied materials & interfaces.

Electron Spin Manipulation via Encaged Cluster: Differing Anion Radicals of Y2@C82-Cs, Y2C2@C82-Cs, and Sc2C2@C82-Cs.

Chunru Wang, Taishan Wang, Li Jiang, 2013, The journal of physical chemistry letters.

Gadofullerene Nanocrystals: A Robust, High-Efficiency Myelosuppressive Protector in Radiotherapy.

Chunru Wang, Chun-ying Shu, Mingming Zhen, 2019, ACS applied bio materials.

Preparation and characterization of two new water-soluble endohedral metallofullerenes as magnetic resonance imaging contrast agents.

Chun-ying Shu, E. Zhang, Chunru Wang, 2007, The journal of physical chemistry. B.

Manganese(III)-catalyzed free radical reactions on trimetallic nitride endohedral metallofullerenes.

H. Gibson, K. Harich, H. Dorn, 2007, Journal of the American Chemical Society.

Removal of multifold heavy metal contaminations in drinking water by porous magnetic Fe2O3@AlO(OH) superstructure

Weiguo Song, Chunru Wang, Taishan Wang, 2013 .

Identification of the Most Stable Sc2C80 Isomers: Structure, Electronic Property, and Molecular Spectra Investigations

Xin Lu, Chunru Wang, Taishan Wang, 2012 .

Construction and photophysics study of supramolecular complexes composed of three-point binding fullerene-trispyridylporphyrin dyads and zinc porphyrin.

Chunru Wang, Taishan Wang, W. Xu, 2011, Physical chemistry chemical physics : PCCP.

Facile synthesis of porous Mn2O3 nanoplates and their electrochemical behavior as anode materials for lithium ion batteries.

Chunru Wang, Yang Yan, Li Jiang, 2014, Chemistry.

High performance ultraviolet photodetectors based on an individual Zn2SnO4 single crystalline nanowire

Chunru Wang, Hongfei Zhu, Li Jiang, 2010 .

Gd2@C79N: isolation, characterization, and monoadduct formation of a very stable heterofullerene with a magnetic spin state of S = 15/2.

Jiechao Ge, Wujun Fu, K. Williams, 2011, Journal of the American Chemical Society.

Synthesis of CuO/graphene nanocomposite as a high-performance anode material for lithium-ion batteries

Yu‐Guo Guo, Chunru Wang, Xing-Long Wu, 2010 .

Modification on the tribological properties of ceramics lubricated by water using fullerenol as a lubricating additive

Jianbin Luo, G. Pan, Yuhong Liu, 2012 .

Chrysanthemum-like α-FeOOH microspheres produced by a simple green method and their outstanding ability in heavy metal ion removal

W. Xu, Weiguo Song, Chunru Wang, 2011 .

Preparation of graphene-like iron oxide nanofilm/silica composite with enhanced adsorption and efficient photocatalytic properties

Weiguo Song, Chunru Wang, Li Jiang, 2013 .

Amino acid functionalized gadofullerene nanoparticles with superior antitumor activity via destruction of tumor vasculature in vivo.

Chunru Wang, Chun-ying Shu, Xue Li, 2017, Biomaterials.

High relaxivity trimetallic nitride (Gd3N) metallofullerene MRI contrast agents with optimized functionality.

Panos P. Fatouros, Harry C. Dorn, Ting Cai, 2010, Bioconjugate chemistry.

Investigation of Gd3N@C2n (40 n 44) family by Raman and inelastic electron tunneling spectroscopy

Jiechao Ge, D. Geohegan, Wujun Fu, 2009, 0910.5273.

Investigation of Gd 2 @C 90 , Gd 2 C 2 @C 92 , and Gd 2 @C 79 N by Raman Spectroscopy

Jiechao Ge, D. Geohegan, Wujun Fu, 2009 .

Planar quinary cluster inside a fullerene cage: synthesis and structural characterizations of Sc(3)NC@C(80)-I(h).

Wei Xu, Kai Tan, Lai Feng, 2010, Journal of the American Chemical Society.

Amino acid modified [70] fullerene derivatives with high radical scavenging activity as promising bodyguards for chemotherapy protection

Chunru Wang, Liang Ma, Chun-ying Shu, 2018, Scientific Reports.

Polystyrene spheres-assisted matrix-assisted laser desorption ionization mass spectrometry for quantitative analysis of plasma lysophosphatidylcholines.

Jingxia Wang, Chun-ying Shu, Shumu Li, 2013, Analytical chemistry.

Two-pronged pulmonary gene delivery strategy: a surface-modified fullerene nanoparticle and a hypotonic vehicle.

H. Cui, J. S. Suk, Chun-ying Shu, 2021, Angewandte Chemie.

A linear molecule functionalized multi-walled carbon nanotubes with well dispersed PtRu nanoparticles for ethanol electro-oxidation

Chunru Wang, Taishan Wang, Li Jiang, 2012 .

Amphiphilic trismethylpyridylporphyrin-fullerene (C70) dyad: an efficient photosensitizer under hypoxia conditions.

Jiechao Ge, Hongmei Su, Chunru Wang, 2015, Journal of materials chemistry. B.

Photoacoustic Imaging Guided Near‐Infrared Photothermal Therapy Using Highly Water‐Dispersible Single‐Walled Carbon Nanohorns as Theranostic Agents

Li Wan, Zhuang Liu, Chunying Chen, 2014 .

Effects of Fullerene Bisadduct Regioisomers on Photovoltaic Performance

Yongfang Li, Chunru Wang, Qi Xu, 2014 .

Controllable fabrication of iron oxide/oxyhydroxide with diverse nanostructures and their excellent performance in visible light induced photocatalytic degradation of rhodamine B.

Chunru Wang, Taishan Wang, Li Jiang, 2012, Journal of Nanoscience and Nanotechnology.

Cellular Uptake, Organelle Enrichment, and In Vitro Antioxidation of Fullerene Derivatives, Mediated by Surface Charge.

Chunru Wang, Chun-ying Shu, Mingming Zhen, 2021, Langmuir : the ACS journal of surfaces and colloids.

Positron Emission Tomography/Magnetic Resonance Imaging of Glioblastoma Using a Functionalized Gadofullerene Nanoparticle.

B. Ross, Chunru Wang, Chun-ying Shu, 2019, ACS applied materials & interfaces.

In vitro and in vivo photothermally enhanced chemotherapy by single-walled carbon nanohorns as a drug delivery system.

L. Wan, Zhuang Liu, Chao Wang, 2014, Journal of materials chemistry. B.

Synthesis and Characterization of a Non-IPR Fullerene Derivative : SC3N@C68[C(COOC2H5 )2]

H. Gibson, H. Dorn, Ting Cai, 2008 .

Selective formation of a symmetric Sc3N@C78 bisadduct: adduct docking controlled by an internal trimetallic nitride cluster.

C. Anklin, H. Gibson, M. Anderson, 2008, Journal of the American Chemical Society.

Russian-doll-type metal carbide endofullerene: synthesis, isolation, and characterization of Sc4C2@C80.

Kai Tan, Ning Chen, Jun-Feng Xiang, 2009, Journal of the American Chemical Society.

89Y and 13C NMR cluster and carbon cage studies of an yttrium metallofullerene family, Y3N@C(2n) (n = 40-43).

Tianming Zuo, Liaosa Xu, Wujun Fu, 2009, Journal of the American Chemical Society.

Size effect of endohedral cluster on fullerene cage: preparation and structural studies of Y3N@C78-C2.

Yongqiang Feng, Wei Xu, Junpeng Zheng, 2011, Nanoscale.

The Discovery of Non-IPR Fullerenes

Chunru Wang, Chun-ying Shu, W. Xu, 2014 .

Preparation and structural characterization of the Ih and the D5h isomers of the endohedral fullerenes Tm3N@C80: icosahedral C80 cage encapsulation of a trimetallic nitride magnetic cluster with three uncoupled Tm3+ ions.

Tianming Zuo, Liaosa Xu, Luis Echegoyen, 2008, Inorganic chemistry.

Synthesis, Isolation, Characterization, and Theoretical Studies of Sc3NC@C78-C2

Li Jiang, Chunru Wang, Taishan Wang, 2011 .

Structural and electronic studies of metal carbide clusterfullerene Sc2C2@Cs-C72.

Yongqiang Feng, Lai Feng, Li Jiang, 2013, Nanoscale.

Highly regioselective derivatization of trimetallic nitride templated endohedral metallofullerenes via a facile photochemical reaction.

Wujun Fu, H. Gibson, K. Harich, 2008, Journal of the American Chemical Society.

The structures of trimetallic nitride fullerenes M3N@C88: Theoretical evidence of corporation between electron transfer interaction and size effect

Chunru Wang, L. Gan, Chun-ying Shu, 2012 .

Spin-active metallofullerene stabilized by the core of an NC moiety.

Chunru Wang, Taishan Wang, C. Ge, 2013, Chemical communications.

Electron Spin Manipulation via Encaged Cluster : Di ff ering Anion Radicals of Y 2 @

Chunru Wang, Taishan Wang, Li Jiang, 2013 .

Biodegradable, Hydrogen Peroxide, and Glutathione Dual Responsive Nanoparticles for Potential Programmable Paclitaxel Release.

L. Wan, Chunru Wang, Chun-ying Shu, 2018, Journal of the American Chemical Society.

Highly Efficient and Thermally Stable Polymer Solar Cells with Dihydronaphthyl‐Based [70]Fullerene Bisadduct Derivative as the Acceptor

Yongfang Li, Chunru Wang, Taishan Wang, 2012 .

Field emission from GeSe2 nanowalls

Chunru Wang, Huibiao Liu, Yuliang Li, 2011 .

Fullerene/photosensitizer nanovesicles as highly efficient and clearable phototheranostics with enhanced tumor accumulation for cancer therapy.

Wei Zhang, Ying Zhang, Xiaojuan Hao, 2016, Biomaterials.

In vitro and in vivo studies of single-walled carbon nanohorns with encapsulated metallofullerenes and exohedrally functionalized quantum dots.

Christopher G. Rylander, P. Fatouros, Jiechao Ge, 2010, Nano letters.

Modification on the tribological properties of ceramics lubricated by water using fullerenol as a lubricating additive

Jianbin Luo, G. Pan, Yuhong Liu, 2012, Science China Technological Sciences.

A highly efficient and tumor vascular-targeting therapeutic technique with size-expansible gadofullerene nanocrystals

Yi Luo, F. Fang, H. Lei, 2015, Science China Materials.

Fullerene-based nanocomplex assists pulmonary delivery of siRNA for treating metastatic lung cancer

Libing Liu, Chun-ying Shu, Xue Li, 2023, Nano Today.

A novel bone marrow targeted gadofullerene agent protect against oxidative injury in chemotherapy

Xue Li, Chunru Wang, Chun-ying Shu, 2017, Science China Materials.

Syntheses and structures of phenyl-C81-butyric acid methyl esters (PCBMs) from M3N@C80.

Chunru Wang, Wujun Fu, H. Azurmendi, 2009, Organic letters.

Effects of alkoxy chain length in alkoxy-substituted dihydronaphthyl-based [60]fullerene bisadduct acceptors on their photovoltaic properties.

Yongfang Li, Chunru Wang, Qi Xu, 2012, ACS applied materials & interfaces.

Eco-friendly synthesis of size-controllable amine-functionalized graphene quantum dots with antimycoplasma properties.

Chunru Wang, Yucheng Wang, N. Huang, 2013, Nanoscale.

Amino acid modified [70] fullerene derivatives with high radical scavenging activity as promising bodyguards for chemotherapy protection

Chunru Wang, Liang Ma, Chun-ying Shu, 2018, Scientific Reports.

Protective effect of C70-carboxyfullerene against oxidative-induced stress on postmitotic muscle cells.

X. Fang, Chunru Wang, Chun-ying Shu, 2013, ACS Applied Materials and Interfaces.

Highly regioselective derivatization of trimetallic nitride templated endohedral metallofullerenes via a facile photochemical reaction.

Wujun Fu, H. Gibson, K. Harich, 2008, Journal of the American Chemical Society.

Biocompatible [60]/[70] Fullerenols: Potent Defense against Oxidative Injury Induced by Reduplicative Chemotherapy.

Chunru Wang, Liping Wang, Li Jiang, 2017, ACS applied materials & interfaces.

Structural effect and mechanism of C70-carboxyfullerenes as efficient sensitizers against cancer cells.

Li Xu, X. Fang, Chunru Wang, 2012, Small.

Oral [60]fullerene reduces neuroinflammation to alleviate Parkinson's disease via regulating gut microbiome

Xia Li, Chun-ying Shu, Mingming Zhen, 2023, Theranostics.

An anti-aromatic isomer of fullerene C60 violating the pentagon adjacent penalty rule

Chunru Wang, L. Gan, Q. Chang, 2012 .