W. J. Thompson

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Synthesis and antiviral activity of a series of HIV-1 protease inhibitors with functionality tethered to the P1 or P1' phenyl substituents: X-ray crystal structure assisted design.

P. Darke, W. Schleif, J. Quintero, 1992, Journal of Medicinal Chemistry.

N,N'-Disuccinimidyl Carbonate: A Useful Reagent for Alkoxycarbonylation of Amines.

Arun K. Ghosh, W. J. Thompson, T. T. Duong, 1992, Tetrahedron letters.

Structure-based design of HIV-1 protease inhibitors: replacement of two amides and a 10 pi-aromatic system by a fused bis-tetrahydrofuran.

P. Anderson, J. Huff, P. Fitzgerald, 1994, Journal of medicinal chemistry.

Design and synthesis of N-alkylated saccharins as selective α-1a adrenergic receptor antagonists☆

R. Chang, Tsing-bau Chen, J. Huff, 1998 .

Sulfonylmethanesulfonamide inhibitors of carbonic anhydrase.

P. Mallorga, W. Randall, S. Graham, 1993, Journal of medicinal chemistry.

Effects of a potent carbonic anhydrase inhibitor on bone resorption in organ culture.

K. Shepard, P. Anderson, G. Rodan, 1988, Endocrinology.

Nonpeptidal P2 ligands for HIV protease inhibitors: structure-based design, synthesis, and biological evaluation.

D. Walters, P. Darke, W. Schleif, 1996, Journal of medicinal chemistry.

Nonpeptidal P2 Ligands for HIV Protease Inhibitors: Structure‐Based Design, Synthesis, and Biological Evaluation.

Arun K. Ghosh, D. Walters, P. Darke, 1996 .

The development of cyclic sulfolanes as novel and high-affinity P2 ligands for HIV-1 protease inhibitors.

P. Darke, M. Holloway, C. Culberson, 1994, Journal of medicinal chemistry.

Potent HIV protease inhibitors: the development of tetrahydrofuranylglycines as novel P2-ligands and pyrazine amides as P3-ligands.

P. Darke, M. Holloway, A. Ghosh, 1993, Journal of medicinal chemistry.

An efficient synthesis of arylpyrazines and bipyridines

J. H. Jones, J. Thies, W. J. Thompson, 1988 .

A general synthesis of 5-arylnicotinates

W. J. Thompson, J. Gaudino, W. Thompson, 1984 .

Synthesis of 2‐Alkylamino‐3‐fluoropyridines Using Buchwald Conditions

W. J. Thompson, P. M. Munson, 2004 .

CYCLIC SULFONE-3-CARBOXAMIDES AS NOVEL P2-LIGANDS FOR Ro 31-8959 BASED HIV-1 PROTEASE INHIBITORS.

Arun K. Ghosh, J. Huff, W. J. Thompson, 1995, Bioorganic & medicinal chemistry letters.

The facile reduction of methoxyethoxymethyl esters with lithium triethylborohydride

W. J. Thompson, R. Ireland, 1980 .

Stereoselective synthesis of the hydroxyethylene isostere of the HIV protease (Tyr-Pro) cleavage site

P. Darke, J. Thies, W. J. Thompson, 1992 .

An Efficient Synthesis of Hydroxyethylene Dipeptide Isosteres: The Core Unit of Potent HIV-1 Protease Inhibitors.

Arun K. Ghosh, W. J. Thompson, S. Mckee, 1991, The Journal of organic chemistry.

3'-Tetrahydrofuranylglycine as a Novel, Unnatural Amino Acid Surrogate for Asparagine in the Design of Inhibitors of the HIV Protease.

Arun K. Ghosh, P. Anderson, P. Darke, 1993, Journal of the American Chemical Society.

A stereocontrolled synthesis of trans-allylic amines

T. Tucker, W. J. Thompson, J. E. Schwering, 1990 .

Stereoselective synthesis of desmethoxy-(+)-verruculogen TR-2

W. J. Thompson, S. Boyd, 1987 .

Approach to the total synthesis of chlorothricolide: synthesis of "7-epi-bottom half" and its union with "top half" systems

W. J. Thompson, R. Ireland, G. Srouji, 1981 .

An approach to the total synthesis of chlorothricolide: the synthesis of the top half

W. J. Thompson, R. Ireland, 1979 .

A highly enantioselective synthesis of phosphate triesters

W. J. Thompson, Kensaku Nakayama, 1990 .

Potent HIV-1 Protease Inhibitors: Stereoselective Synthesis of a Dipeptide Mimic.

Arun K. Ghosh, P. Darke, W. J. Thompson, 1993, The Journal of organic chemistry.

STEREOCONTROLLED SYNTHESIS OF HIV-l PROTEASE INHIBITORS WITH C2-AXIS OF SYMMETRY.

Arun K. Ghosh, W. J. Thompson, S. Mckee, 1991, Tetrahedron letters.

The intramolecular cycloaddition of α-nitrone esters: a stereocontrolled synthesis of γ-hydroxy-α-aminoesters

W. J. Thompson, A. Toy, W. Thompson, 1984 .

An Efficient Synthesis of Functionalized Urethanes from Azides.

Arun K. Ghosh, W. J. Thompson, T. T. Duong, 1992, Journal of the Chemical Society. Chemical communications.

Preparation of methyl 2,5-dioxohexanoate: a highly convenient reagent for the introduction of the 2-carbalkoxy-1,5-dialkylpyrrole nucleus

W. J. Thompson, C. Buhr, 1983 .

Synthesis and pharmacological evaluation of a series of dibenzo[a,d]cycloalkenimines as N-methyl-D-aspartate antagonists.

P. Anderson, J. Thies, W. J. Thompson, 1990, Journal of medicinal chemistry.

HIV-1 protease inhibitors based on hydroxyethylene dipeptide isosteres: an investigation into the role of the P1' side chain on structure-activity.

P. Darke, A. Deana, S. Graham, 1992, Journal of medicinal chemistry.

Benzocycloalkyl amines as novel C-termini for HIV protease inhibitors.

E A Emini, P. Anderson, P. Darke, 1991, Journal of medicinal chemistry.

A Facile and Enantiospecific Synthesis of 2(S)- and 2(R)-[1'(S)-Azido-2-phenylethyl]oxirane.

Arun K. Ghosh, W. J. Thompson, Hee‐Yoon Lee, 1992, Journal of the Chemical Society. Chemical communications.

3-Tetrahydrofuran and pyran urethanes as high-affinity P2-ligands for HIV-1 protease inhibitors.

E A Emini, Arun K. Ghosh, P. Darke, 1993, Journal of medicinal chemistry.

An Efficient Synthesis of Arylpyrazines and Bipyridines.

J. H. Jones, J. Thies, W. J. Thompson, 1988 .

An inexpensive, foolproof apparatus for flash chromatography

W. J. Thompson, B. Hanson, 1984 .

Structure-activity studies and antiviral properties of hydroxyethylene transition state inhibitors of HIV-1 protease

P. Anderson, P. Darke, W. Schleif, 1992 .

HIV-1 protease inhibitory activity of L-694,746, a novel metabolite of L-689,502.

P. Darke, G. Garrity, B. Arison, 1991, Biochemical and biophysical research communications.

A priori prediction of activity for HIV-1 protease inhibitors employing energy minimization in the active site.

T. Halgren, M. Holloway, J. Vacca, 1995, Journal of medicinal chemistry.

Radiosynthesis of the HIV integrase inhibitor [18F]MK‐0518 (Isentress)

D. Hazuda, H. Burns, W. J. Thompson, 2010 .