T. Kurosu

发表

IRF4 negatively regulates proliferation of germinal center B cell-derived Burkitt's lymphoma cell lines and induces differentiation toward plasma cells.

Y. Teng, Yusuke Takahashi, M. Yamada, 2007, European journal of cell biology.

Reactive oxygen species generated by hematopoietic cytokines play roles in activation of receptor-mediated signaling and in cell cycle progression.

T. Kurosu, O. Miura, M. Iiyama, 2006, Cellular signalling.

BCR/ABL activates Rap1 and B-Raf to stimulate the MEK/Erk signaling pathway in hematopoietic cells.

A. Jin, T. Kurosu, O. Miura, 2005, Biochemical and biophysical research communications.

Evaluation of the efficacy of maintenance therapy for low-to-intermediate-risk acute promyelocytic leukemia in molecular remission: A retrospective single-institution study.

T. Kurosu, O. Miura, Keigo Okada, 2015, Molecular and clinical oncology.

Proliferation and Survival Signaling from Both Jak2-V617F and Lyn Involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 Cell Line Newly Established from Acute Myeloid Leukemia Transformed from Polycythemia Vera

T. Kurosu, O. Miura, S. Tohda, 2014, PloS one.

DNA Damage Stress and Inhibition of Jak2-V617F Cause Its Degradation and Synergistically Induce Apoptosis through Activation of GSK3β

T. Kurosu, O. Miura, G. Oshikawa, 2011, PloS one.

c-Cbl and Cbl-b Ligases Mediate 17-Allylaminodemethoxygeldanamycin-induced Degradation of Autophosphorylated Flt3 Kinase with Internal Tandem Duplication through the Ubiquitin Proteasome Pathway*

T. Kurosu, O. Miura, G. Oshikawa, 2011, The Journal of Biological Chemistry.

Molecular mechanisms for enhancement of stromal cell-derived factor 1–induced chemotaxis by platelet endothelial cell adhesion molecule 1 (PECAM-1)

T. Kurosu, O. Miura, G. Oshikawa, 2017, The Journal of Biological Chemistry.

Clonal evolution with double Ph followed by tetraploidy in imatinib-treated chronic myeloid leukemia with e19a2 transcript in transformation.

T. Kurosu, O. Miura, A. Arai, 2010, Cancer genetics and cytogenetics.

BCR/ABL and IL-3 activate Rap1 to stimulate the B-Raf/MEK/Erk and Akt signaling pathways and to regulate proliferation, apoptosis, and adhesion

N. Minato, H. Fujita, A. Jin, 2006, Oncogene.

PECAM-1 is involved in BCR/ABL signaling and may downregulate imatinib-induced apoptosis of Philadelphia chromosome-positive leukemia cells

T. Kurosu, O. Miura, G. Oshikawa, 2012, International journal of oncology.

Inhibition of the PI3K/Akt/GSK3 Pathway Downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD Downregulates DNA Damage-Induced Chk1 Activation as Well as G2/M Arrest and Prominently Enhances Induction of Apoptosis

T. Kurosu, O. Miura, G. Oshikawa, 2013, PloS one.

Clonal evolution with inv(11)(p15q22) and NUP98/DDX10 fusion gene in imatinib-resistant chronic myelogenous leukemia.

T. Kurosu, O. Miura, K. Kakihana, 2005, Cancer genetics and cytogenetics.

p38 MAP kinase plays a role in G2 checkpoint activation and inhibits apoptosis of human B cell lymphoma cells treated with etoposide

T. Koyama, T. Kurosu, T. Koyama, 2005, Apoptosis.

Glycogen synthase kinase-3β and p38 phosphorylate cyclin D2 on Thr280 to trigger its ubiquitin/proteasome-dependent degradation in hematopoietic cells

S. Kotani, T. Kurosu, O. Miura, 2007, Oncogene.

BCL6 overexpression prevents increase in reactive oxygen species and inhibits apoptosis induced by chemotherapeutic reagents in B-cell lymphoma cells

T. Kurosu, O. Miura, T. Miki, 2003, Oncogene.

A novel variant form of MLL-ELL fusion transcript with t(11;19)(q23;p13.1) in chronic myelomonocytic leukemia transforming to acute myeloid leukemia.

T. Kurosu, O. Miura, T. Miki, 2008, Cancer genetics and cytogenetics.

Down regulation of Chk1 by p53 plays a role in synergistic induction of apoptosis by chemotherapeutics and inhibitors for Jak2 or BCR/ABL in hematopoietic cells

T. Kurosu, O. Miura, A. Nogami, 2016, Oncotarget.

Enhancement of imatinib-induced apoptosis of BCR/ABL-expressing cells by nutlin-3 through synergistic activation of the mitochondrial apoptotic pathway

H. Kagechika, T. Kurosu, O. Miura, 2010, Apoptosis.

Sorafenib induces apoptosis specifically in cells expressing BCR/ABL by inhibiting its kinase activity to activate the intrinsic mitochondrial pathway.

Osamu Miura, Hiroyuki Kagechika, H. Kagechika, 2009, Cancer research.

Rottlerin synergistically enhances imatinib-induced apoptosis of BCR/ABL-expressing cells through its mitochondrial uncoupling effect independent of protein kinase C-δ

T. Koyama, M. Yamamoto, T. Kurosu, 2007, Oncogene.

The two major imatinib resistance mutations E255K and T315I enhance the activity of BCR/ABL fusion kinase.

T. Kurosu, O. Miura, K. Kakihana, 2004, Biochemical and biophysical research communications.

Two M‐components in a single cell lineage in a patient with a dual isotype secretory B‐cell tumour

T. Nemoto, Takako Saito, T. Kurosu, 1998, British journal of haematology.

FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia

T. Kurosu, O. Miura, G. Oshikawa, 2015, Oncotarget.

T. Kurosu, O. Miura, C. Sakashita, 2015, Internal medicine.

Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis

T. Kurosu, O. Miura, A. Arai, 2005, Oncogene.

A novel MYD88 mutation, L265RPP, in Waldenström macroglobulinemia activates the NF-κB pathway to upregulate Bcl-xL expression and enhances cell survival

T. Kurosu, O. Miura, G. Oshikawa, 2015, Blood Cancer Journal.

Effects of Colforsin Daropate Hydrochloride (Adehl® Inj.), Anti-Acute Heart Failure Agent, on Adenylate Cyclase-Related Hormone Actions

S. Hosoda, H. Yamashita, H. Matsuda, 2004 .

A variant-type MLL/SEPT9 fusion transcript in adult de novo acute monocytic leukemia (M5b) with t(11;17)(q23;q25)

T. Kurosu, T. Koyama, O. Miura, 2008, International journal of hematology.

Recurrence of chronic active Epstein-Barr virus infection from donor cells after achieving complete response through allogeneic bone marrow transplantation.

Y. Ota, Hisashi Yamamoto, M. Harigai, 2012, Internal medicine.

Adenovirus is a key pathogen in hemorrhagic cystitis associated with bone marrow transplantation.

Qin Chen, K. Ohashi, H. Sakamaki, 2001, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[Bortezomib-induced tumor lysis syndrome with a remarkable elevation of LDH in a case of relapsed and therapy-resistant multiple myeloma].

T. Kurosu, T. Koyama, O. Miura, 2006, [Rinsho ketsueki] The Japanese journal of clinical hematology.

Molecular mechanisms for enhancement of stromal cell-derived factor 1–induced chemotaxis by platelet endothelial cell adhesion molecule 1 (PECAM-1)

T. Kurosu, O. Miura, G. Oshikawa, 2017, The Journal of Biological Chemistry.

[Ischemic colitis following the treatment of acute hemorrhage in a patient with acquired hemophilia A].

T. Kurosu, T. Koyama, O. Miura, 2006, [Rinsho ketsueki] The Japanese journal of clinical hematology.