M. Harmsen

发表

Properties, production, and applications of camelid single-domain antibody fragments

H. de Haard, M. Harmsen, 2007, Applied Microbiology and Biotechnology.

Identification of a novel Fasciola hepatica cathepsin L protease containing protective epitopes within the propeptide.

J. Cornelissen, M. Harmsen, F. V. van Milligen, 2004, International journal for parasitology.

Early immunodiagnosis of fasciolosis in ruminants using recombinant Fasciola hepatica cathepsin L-like protease.

J. Cornelissen, M. Harmsen, C. Gaasenbeek, 2001, International journal for parasitology.

Comparison of physical chemical properties of llama VHH antibody fragments and mouse monoclonal antibodies.

C T Verrips, B. de Geus, C. Verrips, 1999, Biochimica et biophysica acta.

Selection and optimization of proteolytically stable llama single-domain antibody fragments for oral immunotherapy

T. Niewold, M. Harmsen, C. Solt, 2006, Applied Microbiology and Biotechnology.

Isolation of Panels of Llama Single-Domain Antibody Fragments Binding All Nine Neuraminidase Subtypes of Influenza A Virus

Willem Bartelink, G. Koch, M. Harmsen, 2013 .

Llama heavy-chain V regions consist of at least four distinct subfamilies revealing novel sequence features.

B. de Geus, I. Nijman, L. Frenken, 2000, Molecular immunology.

The effect of uniform capture molecule orientation on biosensor sensitivity: dependence on analyte properties.

Vincent J. B. Ruigrok, J. Beekwilder, H. Zuilhof, 2013, Biosensors & bioelectronics.

IMPROVED FUNCTIONAL IMMOBILIZATION OF LLAMA SINGLE-DOMAIN ANTIBODY FRAGMENTS TO POLYSTYRENE SURFACES USING SMALL PEPTIDES

M. Harmsen, H. Fijten, 2012, Journal of immunoassay & immunochemistry.

Enhancement of toxin- and virus-neutralizing capacity of single-domain antibody fragments by N-glycosylation

M. Harmsen, C. Solt, H. Fijten, 2009, Applied Microbiology and Biotechnology.

Passive immunization of pigs with bispecific llama single-domain antibody fragments against foot-and-mouth disease and porcine immunoglobulin.

M. Harmsen, H. Fijten, A. Dekker, 2008, Veterinary microbiology.

Neutralisation of venom-induced haemorrhage by IgG from camels and llamas immunised with viper venom and also by endogenous, non-IgG components in camelid sera.

K. Conrath, R. Harrison, M. Harmsen, 2006, Toxicon : official journal of the International Society on Toxinology.

Prolonged in vivo residence times of llama single-domain antibody fragments in pigs by binding to porcine immunoglobulins.

M. Harmsen, H. Fijten, C. B. van Solt, 2005, Vaccine.

Escherichia coli F4 fimbriae specific llama single-domain antibody fragments effectively inhibit bacterial adhesion in vitro but poorly protect against diarrhoea.

F. V. van Zijderveld, T. Niewold, M. Harmsen, 2005, Veterinary microbiology.

Stimulation of chymosin secretion by simultaneous expression with chymosin-binding llama single-domain antibody fragments in yeast

B. de Geus, M. Harmsen, C. Smits, 2002, Applied Microbiology and Biotechnology.

Multimeric single-domain antibody complexes protect against bunyavirus infections

F. Grosveld, M. Beer, F. Rey, 2020, eLife.

Prevention of diarrhoea using pathogen specific monoclonal antibodies in an experimental enterotoxigenic E. coli infection in germfree piglets.

F. V. van Zijderveld, B. de Geus, M. Harmsen, 1998, The Veterinary quarterly.

Identification of the structural basis of thermal lability of a virus provides a rationale for improved vaccines.

M. G. Mateu, J. M. Sanchez-Ruiz, B. Ibarra-Molero, 2014, Structure.

Stabilizing effects of excipients on dissociation of intact (146S) foot-and-mouth disease virions into 12S particles during storage as oil-emulsion vaccine.

M. Harmsen, D. Westra, H. Fijten, 2015, Vaccine.

Passive immunization of guinea pigs with llama single-domain antibody fragments against foot-and-mouth disease.

M. Harmsen, Rodney A. Rosalia, H. Fijten, 2007, Veterinary microbiology.

Novel Capsid-Specific Single-Domain Antibodies with Broad Foot-and-Mouth Disease Strain Recognition Reveal Differences in Antigenicity of Virions, Empty Capsids, and Virus-Like Particles

Alison Burman, Shiqi Sun, M. Harmsen, 2021, Vaccines.

Effect of thiomersal on dissociation of intact (146S) foot-and-mouth disease virions into 12S particles as assessed by novel ELISAs specific for either 146S or 12S particles.

M. Harmsen, D. Westra, H. Fijten, 2011, Vaccine.

Isolation of Single-Domain Antibody Fragments That Preferentially Detect Intact (146S) Particles of Foot-and-Mouth Disease Virus for Use in Vaccine Quality Control

J. Seago, B. Charleston, M. Harmsen, 2017, Front. Immunol..

A novel single-domain antibody multimer that potently neutralizes tetanus neurotoxin

R. Tierney, P. Stickings, M. Harmsen, 2021, Vaccine: X.

Passive immunization with llama single-domain antibody fragments reduces foot-and-mouth disease transmission between pigs.

B. Engel, M. Harmsen, H. Fijten, 2009, Vaccine.

Fasciola hepatica procathepsin L3 protein expressed by a baculovirus recombinant can partly protect rats against fasciolosis.

K. Bieńkowska-Szewczyk, J. Cornelissen, M. Harmsen, 2005, Vaccine.

Structural and molecular basis for foot-and-mouth disease virus neutralization by two potent protective antibodies

Xiangxi Wang, Hu Dong, Huichen Guo, 2021, Protein & Cell.

Characterization of epitope-tagged foot-and-mouth disease virus

D. Stuart, J. Seago, N. Juleff, 2012, The Journal of general virology.

Chimeric O1K foot-and-mouth disease virus with SAT2 outer capsid as an FMD vaccine candidate

Corey W. Hecksel, D. Stuart, S. Ilca, 2018, Scientific Reports.

Mapping of foot-and-mouth disease virus antigenic sites recognized by single-domain antibodies reveals different 146S particle specific sites and particle flexibility

Shiqi Sun, M. Harmsen, W. V. D. van der Poel, 2023, Frontiers in Veterinary Science.

Small-Scale Secretory VHH Expression in Saccharomyces cerevisiae.

M. Harmsen, P. Willemsen, Marga van Hagen-van Setten, 2022, Methods in molecular biology.

Characterization of foot-and-mouth disease virus antigen by surface-enhanced laser desorption ionization-time of flight-mass spectrometry in aqueous and oil-emulsion formulations.

M. Harmsen, D. Westra, J. Coco-Martin, 2010, Vaccine.

Effect of a pmr 1 disruption and different signal sequences on the intracellular processing and secretion of Cyamopsis tetragonoloba alpha-galactosidase by Saccharomyces cerevisiae.

E. van Tuinen, M. Harmsen, J. Maat, 1993, Gene.