C. Hagemeier

发表

Expression of Late Cell Cycle Genes and an Increased Proliferative Capacity Characterize Very Early Relapse of Childhood Acute Lymphoblastic Leukemia

R. Spang, C. Lottaz, C. Eckert, 2006, Clinical Cancer Research.

Impact of pre‐analytical handling on bone marrow mRNA gene expression

Matthias Nees, Christian Hagemeier, A. Kulozik, 2004, British journal of haematology.

The discovery of 5-formylcytosine in embryonic stem cell DNA.

Markus Müller, Matthias Truss, Christian Hagemeier, 2011, Angewandte Chemie.

Mechanism and stem-cell activity of 5-carboxycytosine decarboxylation determined by isotope tracing.

T. Carell, T. Pfaffeneder, Markus Müller, 2012, Angewandte Chemie.

Human cytomegalovirus tegument protein pp150 acts as a cyclin A2–CDK-dependent sensor of the host cell cycle and differentiation state

J. von Einem, M. Winkler, C. Hagemeier, 2013, Proceedings of the National Academy of Sciences.

The retinoblastoma protein binds E2F residues required for activation in vivo and TBP binding in vitro.

T. Kouzarides, C. Hagemeier, A. Cook, 1993, Nucleic acids research.

Gene expression shift towards normal B cells, decreased proliferative capacity and distinct surface receptors characterize leukemic blasts persisting during induction therapy in childhood acute lymphoblastic leukemia

R. Spang, M. Schrappe, K. Seeger, 2007, Leukemia.

E2F6 initiates stable epigenetic silencing of germline genes during embryonic development

P. Robinson, Michael Weber, J. Hecht, 2021, Nature Communications.

Differential effect of FBN1 mutations on in vitro proteolysis of recombinant fibrillin-1 fragments

P. Robinson, T. Rosenberg, C. Hagemeier, 2000, Human Genetics.

A novel de novo mutation in exon 14 of the fibrillin-1 gene associated with delayed secretion of fibrillin in a patient with a mild Marfan phenotype

P. Robinson, C. Hagemeier, P. Booms, 1997, Human Genetics.

Novel exon skipping mutation in the fibrillin‐1 gene: Two ‘hot spots’ for the neonatal Marfan syndrome

P. Robinson, C. Hagemeier, P. Booms, 1999, Clinical genetics.

Combined effect of proteasome and calpain inhibition on cisplatin-resistant human melanoma cells.

D. Schadendorf, P. Kloetzel, J. Gołąb, 2006, Cancer research.

Human cytomegalovirus prevents replication licensing by inhibiting MCM loading onto chromatin

C. Hagemeier, L. Wiebusch, Ralf Uecker, 2003, EMBO reports.

Use of 5-ethynyl-2'-deoxyuridine labelling and flow cytometry to study cell cycle-dependent regulation of human cytomegalovirus gene expression.

C. Hagemeier, L. Wiebusch, Lüder Wiebusch, 2014, Methods in molecular biology.

Regulation of transcription by E2F1/DP1

D. Trouche, T. Kouzarides, C. Hagemeier, 1995, Journal of Cell Science.

Prognostic value of genetic alterations in children with first bone marrow relapse of childhood B-cell precursor acute lymphoblastic leukemia

Julia C. Engelmann, C. Lottaz, C. Eckert, 2013, Leukemia.

The 72K IE1 and 80K IE2 proteins of human cytomegalovirus independently trans-activate the c-fos, c-myc and hsp70 promoters via basal promoter elements.

J. Sinclair, C. Hagemeier, S. Walker, 1992, The Journal of general virology.

Inhibition of Human Cytomegalovirus Immediate-Early Gene Expression by Cyclin A2-Dependent Kinase Activity

Jennifer D. Oduro, C. Hagemeier, L. Wiebusch, 2012, Journal of Virology.

Genomic organization of the human excitatory amino acid transporter gene GLT‐1

A. Ludolph, T. Meyer, C. Hagemeier, 1997, Neuroreport.

Mutations and deletions of the TP53 gene predict nonresponse to treatment and poor outcome in first relapse of childhood acute lymphoblastic leukemia.

C. Eckert, G. Henze, K. Seeger, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Hydrolytically activated etoposide prodrugs inhibit MDR-1 function and eradicate established MDR-1 multidrug-resistant T-cell leukemia.

Roey J. Amir, G. Gaedicke, R. Reisfeld, 2003, Blood.

Classification : Neoplasia Hydrolytically activated etoposide prodrugs inhibit MDR-1 function and eradicate established MDR-1 multidrug resistant T-cell leukemia

Roey J. Amir, G. Gaedicke, R. Reisfeld, 2003 .

Human Cytomegalovirus 86-Kilodalton IE2 Protein Blocks Cell Cycle Progression in G1

C. Hagemeier, L. Wiebusch, Lüder Wiebusch, 1999, Journal of Virology.

The human cytomegalovirus immediate early 2 protein dissociates cellular DNA synthesis from cyclin‐dependent kinase activation

C. Hagemeier, L. Wiebusch, Lüder Wiebusch, 2001, The EMBO journal.

Human cytomegalovirus immediate-early protein 2 (IE2)-mediated activation of cyclin E is cell-cycle-independent and forces S-phase entry in IE2-arrested cells.

C. Hagemeier, L. Wiebusch, Ralf Uecker, 2003, The Journal of general virology.

Functional interaction between the HCMV IE2 transactivator and the retinoblastoma protein.

T. Kouzarides, R. Caswell, G. Hayhurst, 1994, The EMBO journal.

The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulation.

T. Kouzarides, G. Hayward, C. Chiou, 1993, The Journal of general virology.

Prevalence and prognostic significance of chromosome 21 amplifications in children with relapsed acute lymphoblastic leukemia: the ALL-REZ BFM study group

S. Mundlos, C. Eckert, G. Henze, 2010 .

The human cytomegalovirus 80-kilodalton but not the 72-kilodalton immediate-early protein transactivates heterologous promoters in a TATA box-dependent mechanism and interacts directly with TFIID

T. Kouzarides, R. Caswell, J. Sinclair, 1992, Journal of virology.

General blockade of human cytomegalovirus immediate-early mRNA expression in the S/G2 phase by a nuclear, Daxx- and PML-independent mechanism.

T. Stamminger, C. Hagemeier, Nina Tavalai, 2011, The Journal of general virology.

Cell Cycle-Independent Expression of Immediate-Early Gene 3 Results in G1 and G2 Arrest in Murine Cytomegalovirus-Infected Cells

L. Grabenhenrich, C. Hagemeier, S. Voigt, 2008, Journal of Virology.

- 1-Cell cycle independent expression of immediate early gene 3 results in a G 1 and G 2 arrest in MCMV-infected cells Running title : MCMV and cell cycle

L. Grabenhenrich, C. Hagemeier, S. Voigt, 2008 .

A Role for E2F6 in the Restriction of Male-Germ-Cell-Specific Gene Expression

C. Birchmeier, M. Strehle, R. Kuban, 2005, Current Biology.

c-Fos-induced activation of a TATA-box-containing promoter involves direct contact with TATA-box-binding protein

Andrew J. Bannister, T. Kouzarides, R. Bravo, 1994, Molecular and cellular biology.

A rapid screening system evaluates novel inhibitors of DNA methylation and suggests F-box proteins as potential therapeutic targets for high-risk neuroblastoma

T. Carell, B. Maier, L. Penter, 2015, Targeted Oncology.

Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

Tony Kouzarides, Christian Hagemeier, D. Trouche, 1995, Nature.

The Putative Zinc Finger of the Human Cytomegalovirus IE2 86-Kilodalton Protein Is Dispensable for DNA Binding and Autorepression, Thereby Demarcating a Concise Core Domain in the C Terminus of the Protein

C. Hagemeier, M. Truss, L. Wiebusch, 2004, Journal of Virology.

Human Cytomegalovirus Blocks Tumor Necrosis Factor Alpha- and Interleukin-1β-Mediated NF-κB Signaling

C. Hagemeier, J. Wagner, Iris Gruska, 2006, Journal of Virology.

Down-regulation of the inhibitor of growth 1 (ING1) tumor suppressor sensitizes p53-deficient glioblastoma cells to cisplatin-induced cell death

Andreas von Deimling, Matthias Truss, Christian Hagemeier, 2007, Journal of Neuro-Oncology.

Cross-regulation of viral kinases with cyclin A secures shutoff of host DNA synthesis

M. Selbach, Koshi Imami, C. Hagemeier, 2019, Nature Communications.

The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB.

Andrew J. Bannister, T. Kouzarides, C. Hagemeier, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Short Communication Inhibition of human cytomegalovirus replication by small interfering RNAs

C. Hagemeier, M. Truss, Matthias Truss, 2004 .

Inhibition of human cytomegalovirus replication by small interfering RNAs.

C. Hagemeier, M. Truss, L. Wiebusch, 2004, The Journal of general virology.

PUL21a-Cyclin A2 Interaction is Required to Protect Human Cytomegalovirus-Infected Cells from the Deleterious Consequences of Mitotic Entry

S. Jonjić, C. Hagemeier, H. Neitzel, 2014, PLoS pathogens.

Human Cytomegalovirus Inactivates the G0/G1-APC/C Ubiquitin Ligase by Cdh1 Dissociation

C. Hagemeier, L. Wiebusch, M. Bach, 2005, Cell cycle.

Taking Away the Replication License - HCMV and Its Impact on Cellular DNA Synthesis

C. Hagemeier, L. Wiebusch, Lüder Wiebusch, 2003 .

HuSiDa—the human siRNA database: an open-access database for published functional siRNA sequences and technical details of efficient transfer into recipient cells

Szymon M. Kielbasa, Hanspeter Herzel, Maciej Swat, 2004, Nucleic Acids Res..

Engineering, decoding and systems-level characterization of chimpanzee cytomegalovirus

M. Landthaler, Q. Phan, E. Wyler, 2021, bioRxiv.

CD11b is a therapy resistance- and minimal residual disease-specific marker in precursor B-cell acute lymphoblastic leukemia.

M. Schrappe, G. Basso, W. Ludwig, 2010, Blood.

CD 11 b is a therapy resistance – and minimal residual disease – specific marker in precursor B-cell acute lymphoblastic leukemia

M. Schrappe, G. Basso, W. Ludwig, 2010 .

Synthetic lethal mutations in the cyclin A interface of human cytomegalovirus

C. Hagemeier, Iris Gruska, Barbara Vetter, 2017, PLoS pathogens.

Cyclin-Dependent Kinase Activity Controls the Onset of the HCMV Lytic Cycle

C. Hagemeier, M. Zydek, L. Wiebusch, 2010, PLoS pathogens.

TGGE screening of the entire FBN1 coding sequence in 126 individuals with marfan syndrome and related fibrillinopathies

Flemming Skovby, Christian Hagemeier, P. Robinson, 2002, Human mutation.

Clustering of mutations associated with mild Marfan-like phenotypes in the 3' region of FBN1 suggests a potential genotype-phenotype correlation.

P. Robinson, T. Rosenberg, C. Nienaber, 2000, American journal of medical genetics.

Classic, atypically severe and neonatal Marfan syndrome: twelve mutations and genotype–phenotype correlations in FBN1 exons 24–40

Flemming Skovby, Christian Hagemeier, P. Robinson, 2001, European Journal of Human Genetics.

The Latency-Associated UL138 Gene Product of Human Cytomegalovirus Sensitizes Cells to Tumor Necrosis Factor Alpha (TNF-α) Signaling by Upregulating TNF-α Receptor 1 Cell Surface Expression

C. Hagemeier, J. Wagner, Iris Gruska, 2011, Journal of Virology.

p53- and p21-dependent premature APC/C–Cdh1 activation in G2 is part of the long-term response to genotoxic stress

C. Hagemeier, L. Wiebusch, 2010, Oncogene.

DNA Damage-induced Expression of p53 Suppresses Mitotic Checkpoint Kinase hMps1

H. Mewes, J. Budczies, M. Zeitz, 2006, Journal of Biological Chemistry.

Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3), which promotes viability of Hodgkin/Reed-Sternberg cells.

H. Stein, B. Dörken, M. Hummel, 2006, Blood.

An E2F-like repressor of transcription

Andrew J. Bannister, T. Kouzarides, C. Hagemeier, 1997, Nature.

Binary specification of nonsense codons by splicing and cytoplasmic translation

M. Hentze, G. Neu-Yilik, A. Kulozik, 1998, The EMBO journal.

Human cytomegalovirus blocks tumor necrosis factor alpha- and interleukin-1beta-mediated NF-kappaB signaling.

C. Hagemeier, J. Wagner, Iris Gruska, 2006, Journal of Virology.

IEl Protein but Can Be Compensated for by Other LTR Regions

J. Sissons, J. Sinclair, C. Hagemeier, 2022 .

Constructive and Mechanised Meta-Theory of Intuitionistic Epistemic Logic

Dominik Kirst, Christian Hagemeier, Dominik Kirst, 2021, LFCS.

Constructive and mechanised meta-theory of IEL and similar modal logics

Dominik Kirst, C. Hagemeier, 2022, J. Log. Comput..

Human cytomegalovirus immediate-early protein 2 (IE2)-mediated activation of cyclin E is cell-cycle-independent and forces S-phase entry in IE2-arrested cells.

C. Hagemeier, Ralf Uecker, Jasmin Asmar, 2003, The Journal of general virology.

Site-directed mutagenesis using a uracil-containing phagemid template.

C. Hagemeier, 1996, Methods in molecular biology.