H. Liou

发表

The c‐Rel subunit of nuclear factor‐κB regulates murine liver inflammation, wound‐healing, and hepatocyte proliferation

M. Ebrahimkhani, J. Caamaño, P. Raychaudhuri, 2010, Hepatology.

The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms.

G P Nolan, G. Nolan, D. Baltimore, 1993, Genes & development.

C-type lectin OCILRP2/Clr-g and its ligand NKRP1f costimulate T cell proliferation and IL-2 production.

R. Nuñez, H. Liou, J. Tumang, 2005, Cellular immunology.

Id1 Potentiates NF-κB Activation upon T Cell Receptor Signaling*

H. Liou, Xiao-Hong Sun, Yuanzheng Yang, 2006, Journal of Biological Chemistry.

Antigen receptor‐induced B lymphocyte apoptosis mediated via a protease of the caspase family

H. Liou, S. Andjelic, 1998, European journal of immunology.

BCR-mediated apoptosis associated with negative selection of immature B cells is selectively dependent on Pten

P. Pandolfi, H. Liou, X. Fang, 2009, Cell Research.

Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome.

M. Greene, YOUHAI H. Chen, Y. Tone, 2009, Immunity.

GATA-6 and NF-κB Activate CPI-17 Gene Transcription and Regulate Ca2+ Sensitization of Smooth Muscle Contraction

A. Wein, S. Zderic, H. Liou, 2012, Molecular and Cellular Biology.

Selective loss of c-Rel compromises dendritic cell activation of T lymphocytes.

D. Boffa, M. Suthanthiran, R. DeMatteo, 2003, Cellular immunology.

c-Rel regulation of the cell cycle in primary mouse B lymphocytes.

S. Dowdy, H. Liou, A. Owyang, 2002, International immunology.

Late-onset Parkinsonism in NFκB/c-Rel-deficient mice

M. A. De Luca, M. Spillantini, P. Spano, 2012, Brain : a journal of neurology.

NF-kappa B1 p50 is required for BLyS attenuation of apoptosis but dispensable for processing of NF-kappa B2 p100 to p52 in quiescent mature B cells.

I. Maclennan, S. Chen‐Kiang, J. Caamaño, 2003, Journal of immunology.

CD30 is a CD40-inducible molecule that negatively regulates CD40-mediated immunoglobulin class switching in non-antigen-selected human B cells.

P. Casali, H. Zan, R. Goodwin, 1998, Immunity.

Targeting metabolism and survival in chronic lymphocytic leukemia and Richter syndrome cells by a novel NF-κB inhibitor

S. Deaglio, F. Arruga, Samedy Ouk, 2017, Haematologica.

The NFKB Inducing Kinase Modulates Hematopoiesis During Stress

R. Schmid, M. Fresno, J. Segovia, 2015, Stem cells.

Role of the NF-κB transcription factor c-Rel in the generation of CD8+ T-cell responses to Toxoplasma gondii.

C. Hunter, H. Liou, Christopher D Dupont, 2010, International immunology.

The NF‐kappa B p50 precursor, p105, contains an internal I kappa B‐like inhibitor that preferentially inhibits p50.

D. Baltimore, S. Ghosh, T. Fujita, 1992, The EMBO journal.

Bim and Noxa Are Candidates to Mediate the Deleterious Effect of the NF-κB Subunit RelA in Cerebral Ischemia

D. Inta, P. Spano, R. Schmid, 2006, The Journal of Neuroscience.

Essential Roles of c-Rel in TLR-Induced IL-23 p19 Gene Expression in Dendritic Cells1

R. Carmody, H. Liou, Q. Ruan, 2007, The Journal of Immunology.

Gene Expression in Dendritic Cells IL-23 p 19 Essential Roles of c-Rel in TLR-Induced

R. Carmody, H. Liou, Q. Ruan, 2006 .

An HLA-DRα promoter DNA-binding protein is expressed ubiquitously and maps to human chromosomes 22 and 5

R. Eddy, T. Shows, C. Griscelli, 2004, Immunogenetics.

NF-κB factor c-Rel mediates neuroprotection elicited by mGlu5 receptor agonists against amyloid β-peptide toxicity

P. Spano, M. Bähr, M. Pizzi, 2005, Cell Death and Differentiation.

NF-kappaB factor c-Rel mediates neuroprotection elicited by mGlu5 receptor agonists against amyloid beta-peptide toxicity.

P. Spano, M. Bähr, M. Pizzi, 2005, Cell death and differentiation.

Role for IkappaBalpha, but not c-Rel, in skeletal muscle atrophy.

S. Kandarian, R. Jackman, A. Judge, 2007, American journal of physiology. Cell physiology.

c-Rel is crucial for lymphocyte proliferation but dispensable for T cell effector function.

Kendall A. Smith, K. Smith, H. Liou, 1999, International immunology.

Enforced c-REL deficiency prolongs survival of islet allografts1

D. Boffa, Dolca Thomas, Hua Yang, 2002, Transplantation.

Transcriptional Regulation of Type I Diabetes by NF-κB 1

B. Hilliard, H. Liou, S. Lamhamedi-Cherradi, 2003, The Journal of Immunology.

Differential Requirement for NF-κB Family Members in Control of Helminth Infection and Intestinal Inflammation1

C. Hunter, J. Caamaño, S. Shapira, 2002, The Journal of Immunology.

References Subscriptions Permissions Email Alerts NF-κB/Rel Transcription Factors: c-Rel Promotes Airway Hyperresponsiveness and Allergic Pulmonary Inflammation

G. T. Sanctis, L. Kobzik, Hongzhen He, 2013 .

Opposing Roles for RelB and Bcl-3 in Regulation of T-Box Expressed in T Cells, GATA-3, and Th Effector Differentiation 1

M. Boothby, H. Liou, U. Siebenlist, 2005, Journal of Immunology.

Th Effector Differentiation Regulation of T-Box Expressed in T Cells , Opposing Roles for RelB and Bcl-3 in Siebenlist

M. Boothby, H. Liou, U. Siebenlist, 2005 .

phosphorylation-dependent manner. interacts with NF-kappa B p50 and p52 in a kappa B-like molecule that preferentially The bcl-3 proto-oncogene encodes a nuclear I

G. Nolan, M. Scott, K. Bhatia, 2014 .

A DNA binding protein regulated by IL-4 and by differentiation in B cells.

L. Glimcher, M. Boothby, E. Gravallese, 1988, Science.

c-Rel-dependent priming of naive T cells by inflammatory cytokines.

R. Sen, H. Liou, Daliya Banerjee, 2005, Immunity.

The bcl-3 Proto-Oncogene Encodes a Nuclear IidB-Like Molecule That Preferentially Interacts with NF-KB p50 and p52 in a Phosphorylation-Dependent Manner

G. Nolan, H. Liou, Scott, 2003 .

Id1 Potentiates NF-κB Activation upon TCR Signaling

H. Liou, Xiao-Hong Sun, Yuanzheng Yang, 2006 .

RNAi-Mediated c-Rel Silencing Leads to Apoptosis of B Cell Tumor Cells and Suppresses Antigenic Immune Response In Vivo

H. Liou, Wenzhi Tian, 2009, PloS one.

Control of transcription at the murine Aα locus

L. Glimcher, M. Boothby, E. Gravallese, 1990, Immunologic research.

Distinct cloned class II MHC DNA binding proteins recognize the X box transcription element.

L. Glimcher, M. Boothby, H. Liou, 1988, Science.

Differences in DNA sequence specificity among MHC class II X box binding proteins.

L. Glimcher, M. Boothby, H. Liou, 1989, Journal of immunology.

NF-kB inhibitor blocks B cell development at two checkpoints

W. Pear, H. Liou, Shuhua Cheng, 2004, Medical immunology.

A cDNA for a human cyclic AMP response element-binding protein which is distinct from CREB and expressed preferentially in brain

L. Ivashkiv, H. Liou, L. Glimcher, 1990 .

Sequential induction of NF-kappa B/Rel family proteins during B-cell terminal differentiation

D. Baltimore, H. Liou, W. Sha, 1994 .

Regulation of Nuclear Factor (cid:1) B in the Hippocampus by Group I Metabotropic Glutamate Receptors

J. Sweatt, P. Spano, M. Pizzi, 2006 .

Human X-box-binding protein 1 is required for the transcription of a subset of human class II major histocompatibility genes and forms a heterodimer with c-fos.

Santa Jeremy Ono, J. Strominger, L. Glimcher, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Differential induction of class II gene expression in murine pre-B-cell lines by B-cell stimulatory factor-1 and by antibodies to B-cell surface antigens.

W. Paul, L. Glimcher, J. Bonventre, 1988, The Journal of molecular and cellular immunology : JMCI.

Opposing roles of NF-κB family members in the regulation of NK cell proliferation and production of IFN-γ

C. Tato, C. Hunter, S. Shapira, 2006 .

NF-κB inducible genes BCL-X and cyclin E promote immature B-cell proliferation and survival

J. Monroe, H. Liou, Shuhua Cheng, 2004 .

Silencing OCILRP2 leads to intrinsic defects in T cells in response to antigenic stimulation.

H. Liou, Wenzhi Tian, B. Feng, 2005, Cellular immunology.

T Cell-Intrinsic Expression of c-Rel Regulates Th1 Cell Responses Essential for Resistance to Toxoplasma gondii1

C. Hunter, H. Liou, N. Mason, 2004, The Journal of Immunology.

Quiescent Mature B Cells B 2 p 100 to p 52 in κ Processing of NF-Attenuation of Apoptosis but Dispensable for B 1 p 50 Is Required for BLyS κ

I. Maclennan, S. Chen‐Kiang, J. Caamaño, 2003 .

Regulation of the NF-?B/rel transcription factor and I?B inhibitor system

David Baltimore, D. Baltimore, H. Liou, 1993 .

The Ubiquitin-homology Protein, DAP-1, Associates with Tumor Necrosis Factor Receptor (p60) Death Domain and Induces Apoptosis*

H. Liou, M. Liou, 1999, The Journal of Biological Chemistry.

Opposing roles for NF-kappa B/Rel factors p65 and c-Rel in the modulation of neuron survival elicited by glutamate and interleukin-1beta.

P. Spano, M. Pizzi, H. Liou, 2002, The Journal of biological chemistry.

The p65 subunit of NF-KB regulates IKB by two distinct mechanisms

G. Nolan, M. Scott, T. Fujita, 2007 .

Leptin Is Induced in the Ischemic Cerebral Cortex and Exerts Neuroprotection Through NF-&kgr;B/c-Rel–Dependent Transcription

P. Spano, E. Nisoli, M. Pizzi, 2009, Stroke.

A Novel Mechanism of TRAF Signaling Revealed by Structural and Functional Analyses of the TRADD–TRAF2 Interaction

Young Chul Park, David G. Myszka, Hao Wu, 2000, Cell.

The Th17 immune response is controlled by the Rel–RORγ–RORγT transcriptional axis

A. Beg, H. Liou, Junmei Wang, 2011, The Journal of experimental medicine.

The roles of c‐rel and interleukin‐2 in tolerance: a molecular explanation of self–nonself discrimination

Kendall A. Smith, H. Liou, Kendall A. Smith, 2011, Immunology and cell biology.

NF-kappaB inducible genes BCL-X and cyclin E promote immature B-cell proliferation and survival.

J. Monroe, H. Liou, Shuhua Cheng, 2004, Cellular immunology.

Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation.

Jing Sun, C. Hunter, B. Hilliard, 2002, The Journal of clinical investigation.

Cutting Edge: Identification of c-Rel-Dependent and -Independent Pathways of IL-12 Production During Infectious and Inflammatory Stimuli1

C. Hunter, J. Aliberti, H. Liou, 2002, The Journal of Immunology.

Modulation of NF-κB Activity and Apoptosis in Chronic Lymphocytic Leukemia B Cells1

E. Schattner, J. Mascarenhas, H. Liou, 2000, The Journal of Immunology.

Modulation of NF-kappa B activity and apoptosis in chronic lymphocytic leukemia B cells.

E. Schattner, J. Mascarenhas, H. Liou, 2000, Journal of immunology.

mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element

I. Verma, L. Glimcher, L. Ivashkiv, 1990, Molecular and cellular biology.

The bcl-3 proto-oncogene encodes a nuclear I kappa B-like molecule that preferentially interacts with NF-kappa B p50 and p52 in a phosphorylation-dependent manner

G. Nolan, D. Baltimore, M. Scott, 1993, Molecular and cellular biology.

Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses

David Baltimore, D. Baltimore, E. Tuomanen, 1995, Cell.

DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide

G. Nolan, D. Baltimore, P. Tempst, 1991, Cell.

Direct Rel/NF-κB inhibitors: structural basis for mechanism of action.

Samedy Ouk, H. Liou, M. Liou, 2009, Future medicinal chemistry.

A Bioinformatics Analysis of Memory Consolidation Reveals Involvement of the Transcription Factor c-Rel

J. Sweatt, K. Worley, Sangdun Choi, 2004, The Journal of Neuroscience.

c-Rel, an NF-kappaB family transcription factor, is required for hippocampal long-term synaptic plasticity and memory formation.

J. Sweatt, F. Lubin, H. Liou, 2008, Learning & memory.

NF-κB/Rel Transcription Factor Family

H. Liou, 2006 .

Opposing Roles for NF-κB/Rel Factors p65 and c-Rel in the Modulation of Neuron Survival Elicited by Glutamate and Interleukin-1β*

P. Spano, M. Pizzi, H. Liou, 2002, The Journal of Biological Chemistry.

Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages.

A. Hoffmann, D. Baltimore, S. Smale, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Rel-associated pp40: an inhibitor of the rel family of transcription factors.

D. Baltimore, P. Tempst, S. Ghosh, 1991, Science.

NF-κB and Immune Cell Effector Functions

H. Liou, Wenzhi Tian, Shuhua Cheng, 2006 .

The Th17 immune response is controlled by a c-Rel-ROR{gamma}-ROR{gamma}T transcriptional axis

A. Beg, H. Liou, Junmei Wang, 2010 .

IL-6 rescues the hyporesponsiveness of c-Rel deficient B cells independent of Bcl-xL, Mcl-1, and Bcl-2.

J. Bromberg, H. Liou, J. Tumang, 2002, Cellular immunology.

The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers.

G. Nolan, D. Baltimore, M. Scott, 1993, Genes & development.

Survival of leukemic B cells promoted by engagement of the antigen receptor.

E. Cesarman, E. Schattner, A. Bernal, 2001, Blood.

NF-κB1 p50 Is Required for BLyS Attenuation of Apoptosis but Dispensable for Processing of NF-κB2 p100 to p52 in Quiescent Mature B Cells1

I. Maclennan, S. Chen‐Kiang, J. Caamaño, 2003, The Journal of Immunology.

Phosphatidylinositol 3-Kinase and NF-κB/Rel Are at the Divergence of CD40-Mediated Proliferation and Survival Pathways

T. Kadowaki, S. Koyasu, Harumi Suzuki, 2000, The Journal of Immunology.

c‐Rel is essential for B lymphocyte survival and cell cycle progression

R. Hardy, H. Liou, J. Tumang, 1998, European journal of immunology.

Nuclear Factor κb Is Required for the Development of Marginal Zone B Lymphocytes

Bruce H. Horwitz, S. Pillai, B. Horwitz, 2000, The Journal of experimental medicine.

Id1 potentiates NF-kappaB activation upon T cell receptor signaling.

H. Liou, Xiao-Hong Sun, Yuanzheng Yang, 2006, Journal of Biological Chemistry.

Cyclin E and Bcl-xL cooperatively induce cell cycle progression in c-Rel−/− B cells

G. Leone, H. Liou, Shuhua Cheng, 2003, Oncogene.

Opposing roles of NF-kappaB family members in the regulation of NK cell proliferation and production of IFN-gamma.

C. Tato, C. Hunter, S. Shapira, 2006, International immunology.

Homeostatic cell-cycle control by BLyS: Induction of cell-cycle entry but not G1/S transition in opposition to p18INK4c and p27Kip1.

S. Ely, A. Cunningham, I. Maclennan, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Molecular profiling of the role of the NF‐κB family of transcription factors during alloimmunity

T. Mueller, M. Boothby, Hongzhen He, 2002, Journal of leukocyte biology.

Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event

A. Hoffmann, S. Smale, H. Liou, 2001, Nature Immunology.

Targeted Lymphoma Therapy Using a Gold Nanoframework-Based Drug Delivery System.

Samedy Ouk, H. Liou, Manpreet Bariana, 2023, ACS applied materials & interfaces.

A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter.

N. Zeleznik-Le, L. Glimcher, J. Ting, 1990, Science.

Sequential induction of NF-kappa B/Rel family proteins during B-cell terminal differentiation.

D. Baltimore, M. Scott, H. Liou, 1994, Molecular and cellular biology.

Distinctions between c‐Rel and other NF‐κB proteins in immunity and disease

H. Liou, C. Hsia, 2003 .

Regulation of the Immune System by NF-κB and IκB

H. Liou, Hsiou-Chi Liou, 2002 .

c-Rel Is Required for the Protection of B Cells from Antigen Receptor-Mediated, But Not Fas-Mediated, Apoptosis1

T. Behrens, T. Rothstein, H. Liou, 2001, The Journal of Immunology.

NF-kappa B/Rel transcription factors: c-Rel promotes airway hyperresponsiveness and allergic pulmonary inflammation.

G. T. Sanctis, L. Kobzik, P. Finn, 1999, Journal of immunology.

A small-molecule c-Rel inhibitor reduces alloactivation of T cells without compromising antitumor activity.

G. Altan-Bonnet, M. V. D. van den Brink, C. Lezcano, 2014, Cancer discovery.

CD30/TNF receptor-associated factor interaction: NF-kappa B activation and binding specificity.

S. Lee, G. Kandala, H. Liou, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of Nuclear Factor κB in the Hippocampus by Group I Metabotropic Glutamate Receptors

P. Spano, M. Pizzi, H. Liou, 2006, The Journal of Neuroscience.

Transcriptional regulation of MHC class II gene expression: are MHC class II genes coordinately regulated?

L. Glimcher, L. Ivashkiv, H. Liou, 1990 .

Molecular cloning, germ-line transformation, and transcriptional analysis of the zeste locus of Drosophila melanogaster.

P. Gunaratne, M. Goldberg, H. Liou, 1986, Proceedings of the National Academy of Sciences of the United States of America.

a rel-Related Polypeptide

G. Nolan, D. Baltimore, P. Tempst, 1991 .

Regulation of the NF-kappa B/rel transcription factor and I kappa B inhibitor system.

D. Baltimore, H. Liou, D Baltimore, 1993, Current opinion in cell biology.

A cDNA for a human cyclic AMP response element-binding protein which is distinct from CREB and expressed preferentially in brain.

L. Glimcher, L. Ivashkiv, H. Liou, 1990, Molecular and cellular biology.

Regulation of the immune system by NF-kappaB and IkappaB.

H. Liou, Hsiou-Chi Liou, 2002, Journal of biochemistry and molecular biology.

Role for IκBα, but not c-Rel, in skeletal muscle atrophy

S. Kandarian, R. Jackman, A. Judge, 2007 .

DNA binding and I kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide.

G. Nolan, D. Baltimore, P. Tempst, 1991, Cell.

Inhibition of NF-κB DNA binding suppresses myeloma growth via intracellular redox and tumor microenvironment modulation.

R. Feinman, G. Heller, Samedy Ouk, 2022, Molecular Cancer Therapeutics.

Survival Pathways Are at the Divergence of CD 40-Mediated B / Rel κ Phosphatidylinositol 3-Kinase and NF

T. Kadowaki, S. Koyasu, Harumi Suzuki, 2000 .

Transcriptional regulation of type I diabetes by NF-kappa B.

B. Hilliard, H. Liou, S. Lamhamedi-Cherradi, 2003, Journal of immunology.

Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-κB-Controlled Oxidative Stress Responses.

Emily R. Levy, C. Ziegler, M. V. D. van den Brink, 2016, Cancer research.

NF-κB factor c-Rel mediates neuroprotection elicited by mGlu5 receptor agonists against amyloid β-peptide toxicity

P. Spano, M. Bähr, M. Pizzi, 2005, Cell Death and Differentiation.

Distinctions between c-Rel and other NF-kappaB proteins in immunity and disease.

H. Liou, C. Hsia, 2003, BioEssays : news and reviews in molecular, cellular and developmental biology.

A Novel Mechanism of TRAF Signaling Revealed by Structural and Functional Analyses of the TRADD – TRAF 2 Interaction resistance , multiple organ failure

R. Rich, D. Myszka, Y. Park, 2000 .

The c‐Rel subunit of nuclear factor‐κB regulates murine liver inflammation, wound‐healing, and hepatocyte proliferation

M. Ebrahimkhani, J. Caamaño, P. Raychaudhuri, 2010, Hepatology.

Leptin Is Induced in the Ischemic Cerebral Cortex and Exerts Neuroprotection Through NF-&kgr;B/c-Rel–Dependent Transcription

P. Spano, E. Nisoli, M. Pizzi, 2009, Stroke.