Megan H. Powdrill

发表

The role of microRNAs in metabolic interactions between viruses and their hosts.

R. Singaravelu, J. Pezacki, Megan H. Powdrill, 2016, Current opinion in virology.

Contribution of a mutational bias in hepatitis C virus replication to the genetic barrier in the development of drug resistance

Roger D. Kouyos, Evguenia S. Svarovskaia, Robert A. Kozak, 2011, Proceedings of the National Academy of Sciences.

MicroRNA-7 mediates cross-talk between metabolic signaling pathways in the liver

Rodney K. Lyn, R. Singaravelu, J. Pezacki, 2018, Scientific Reports.

Pyrophosphorolytic Excision of Nonobligate Chain Terminators by Hepatitis C Virus NS5B Polymerase

J. Deval, Megan H. Powdrill, M. Götte, 2007, Antimicrobial Agents and Chemotherapy.

1 Dynamics of HCV RNA-dependent RNA Polymerase NS 5 B in Complex with RNA

G. Cosa, J. Bernatchez, P. Karam, 2014 .

Inhibitors of the Hepatitis C Virus RNA-Dependent RNA Polymerase NS5B

J. Bernatchez, Megan H. Powdrill, M. Götte, 2010, Viruses.

Antiviral Activity and Mode of Action of TMC647078, a Novel Nucleoside Inhibitor of the Hepatitis C Virus NS5B Polymerase

B. Samuelsson, S. Eriksson, L. Leclercq, 2011, Antimicrobial Agents and Chemotherapy.

Hydrophobic Triaryl‐Substituted β‐Lactams as Activity‐Based Probes for Profiling Eukaryotic Enzymes and Host–Pathogen Interactions

Neda Nasheri, Craig S. McKay, J. Pezacki, 2014, Chembiochem : a European journal of chemical biology.

Reactivity of N-acyl hydrazone probes with the mammalian proteome.

J. Pezacki, Megan H. Powdrill, A. R. Sherratt, 2021, RSC medicinal chemistry.

A bifunctional nucleoside probe for the inhibition of the human immunodeficiency virus-type 1 reverse transcriptase.

A. Mouland, J. Pezacki, Megan H. Powdrill, 2020, Bioconjugate chemistry.

Hepatitis C virus helicase binding and activity monitored through site-specific labeling using an expanded genetic code.

G. Cosa, J. Pezacki, Megan H. Powdrill, 2019, ACS infectious diseases.

Suppressing RNA silencing with small molecules and the viral suppressor of RNA silencing protein p19.

J. Pezacki, Megan H. Powdrill, S. O’Hara, 2015, Biochemical and biophysical research communications.

Synthesis and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methyl-7-deazapurine nucleosides, their phosphoramidate prodrugs and 5'-triphosphates.

R. Schinazi, Megan H. Powdrill, M. Götte, 2011, Bioorganic & medicinal chemistry letters.

Mechanism of Hepatitis C Virus RNA Polymerase Inhibition with Dihydroxypyrimidines

R. De Francesco, F. Narjes, J. Deval, 2009, Antimicrobial Agents and Chemotherapy.

Dynamics of Hepatitis C Virus (HCV) RNA-dependent RNA Polymerase NS5B in Complex with RNA*

Jean Bernatchez, Gonzalo Cosa, G. Cosa, 2014, The Journal of Biological Chemistry.

Antiviral activity and mode of action of TMC 647078 , a novel 1 nucleoside inhibitor of the HCV NS 5 B polymerase 2 Running title : Characterization of HCV nucleoside inhibitor TMC 647078 3 4

B. Samuelsson, S. Eriksson, L. Leclercq, 2011 .

Chemical Methods for Probing Virus-Host Proteomic Interactions.

J. Pezacki, Megan H. Powdrill, Tyler A. Shaw, 2016, ACS infectious diseases.

MicroRNA-124 Regulates Fatty Acid and Triglyceride Homeostasis

R. Singaravelu, J. Pezacki, Megan H. Powdrill, 2018, iScience.

Site-specific crosslinking of a p19 viral suppressor of RNA silencing protein and its RNA targets using an expanded genetic code.

Dana V. Foss, J. Pezacki, Megan H. Powdrill, 2019, Biochemistry.

Antiviral Activity and Mode of Action of TMC647078, a Novel Nucleoside Inhibitor of the Hepatitis C Virus NS5B Polymerase

B. Samuelsson, S. Eriksson, L. Leclercq, 2011, Antimicrobial Agents and Chemotherapy.

Suppressing RNA silencing with small molecules and the viral suppressor of RNA silencing protein p19.

J. Pezacki, Megan H. Powdrill, S. O’Hara, 2015, Biochemical and biophysical research communications.

Mechanism of Hepatitis C Virus RNA Polymerase Inhibition with Dihydroxypyrimidines

F. Narjes, J. Deval, Megan H. Powdrill, 2009, Antimicrobial Agents and Chemotherapy.