J. Denef

J. Denef, M. Many, S. Maniratunga, 2009, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

Evidence for co-ordinated changes between vascular endothelial growth factor and nitric oxide synthase III immunoreactivity, the functional status of the thyroid follicles, and the microvascular bed during chronic stimulation by low iodine and propylthiouracyl in old mice.

I. Colin, J. Denef, M. Many, 2000, European journal of endocrinology.

Precocity of the endothelial proliferation during a course of rapid goitrogenesis.

J. Denef, S. Haumont, M. Many, 1984, Acta endocrinologica.

Membrane labeling with cationized ferritin in isolated thyroid follicles.

J. Denef, R. Ekholm, 1980, Journal of ultrastructure research.

Direct toxic effect of iodide in excess on iodine-deficient thyroid glands: epithelial necrosis and inflammation associated with lipofuscin accumulation.

I. Colin, J. Denef, M. Many, 1986, Experimental and molecular pathology.

Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease.

S. Costagliola, G. Vassart, S. Refetoff, 2000, The Journal of clinical investigation.

Discovery and Clinical Evaluation of MK‐8150, A Novel Nitric Oxide Donor With a Unique Mechanism of Nitric Oxide Release

Peggy H. Wong, D. Cully, Amjad Ali, 2016, Journal of the American Heart Association.

Changes in cAMP-dependent and Ca2+-phospholipid-dependent protein kinase activities in suspension cultures of porcine thyroid cells

B. Haye, J. Denef, M. Breton, 1990, Molecular and Cellular Endocrinology.

Pharmacological properties of the new potent diuretic torasemide in rats and dogs.

M. Gerin, J. Willems, J. Denef, 1985, Arzneimittel-Forschung.

Subtypes of Madin-Darby canine kidney (MDCK) cells defined by immunocytochemistry: Further evidence for properties of renal collecting duct cells

O. Devuyst, J. Denef, R. Beauwens, 1994, Cell and Tissue Research.

Thiocyanate induces cell necrosis and fibrosis in selenium- and iodine-deficient rat thyroids: a potential experimental model for myxedematous endemic cretinism in central Africa.

G. D. de Escobar, J. Dumont, J. Denef, 2004, Endocrinology.

Cell necrosis and apoptosis are differentially regulated during goitre development and iodine-induced involution.

J. Denef, M. Many, M. van den Hove, 2002, The Journal of endocrinology.

Antigoitrogenic effect of combined supplementation with dl-alpha-tocopherol, ascorbic acid and beta-carotene and of dl-alpha-tocopherol alone in the rat.

I. Colin, J. Denef, M. Many, 1998, The Journal of endocrinology.

Site‐dependent pathological differences in smooth muscles and skeletal muscles of the adult MDX mouse

J. Gillis, J. Denef, B. Boland, 1995, Muscle & nerve.

Studies of Thiaheterocyclic Derivatives .1. Synthesis and Pharmacological Screening

C. Beckers, J. Denef, L. Thunus, 1984 .

Ultrastructure of the thyroid in dwarf mice.

J. Denef, A. Cordier, S. Haumont, 1976, The American journal of anatomy.

Thyroid gland in dwarf mice

J. Denef, A. Cordier, S. Haumont, 1976, Cell and Tissue Research.

The influence of thyrotropin and growth hormone on the thyroid gland in the hereditary dwarf mouse: a morphometric study.

C. Beckers, J. Denef, A. Cordier, 1980, Endocrinology.

Selenium deficiency and thyroid fibrosis. A key role for macrophages and transforming growth factor β (TGF-β)

O. Moine, J. Dumont, J. Denef, 1996, Molecular and Cellular Endocrinology.

Detection of Mycobacterium avium subsp.paratuberculosis in Infected Tissues by New Species-Specific Immunohistological Procedures

H. Bazin, D. Latinne, J. Denef, 1998, Clinical Diagnostic Laboratory Immunology.

C. Beckers, J. Denef, S. Haumont, 1981, Endocrinology.

Pharmacokinetic Interaction of HCV Protease Inhibitor MK-5172 and Ritonavir in Healthy subjects

J. Wagner, J. Denef, J. Hoon, 2013 .

Recent insights into the cell biology of thyroid angiofollicular units.

I. Colin, B. Lengelé, J. Denef, 2013, Endocrine reviews.

Recent Insights into the Cell Biology of Thyroid Angiofollicular Units Ides

M. Colin, B. Lengelé, J. Denef, 2013 .

Expression of nitric oxide synthase isoforms in the thyroid gland: evidence for a role of nitric oxide in vascular control during goiter formation.

T. Lüscher, J. Jameson, I. Colin, 1995, Endocrinology.

Iodine-deficiency-induced long lasting angiogenic reaction in thyroid cancers occurs via a vascular endothelial growth factor-hypoxia inducible factor-1-dependent, but not a reactive oxygen species-dependent, pathway.

S. Baatout, I. Colin, J. Denef, 2012, Thyroid : official journal of the American Thyroid Association.

Detection and identification of endothelin-1 immunoreactivity in rat and porcine thyroid follicular cells.

I. Colin, J. Ketelslegers, J. Denef, 1992, Endocrinology.

I. Colin, J. Denef, M. V. Hove, 1990, Molecular and Cellular Endocrinology.

Structural and functional characteristics of isolated thyroid follicles.

J. Denef, U. Björkman, R. Ekholm, 1980, Journal of ultrastructure research.

Correlation between the loss of thyroglobulin iodination and the expression of thyroid-specific proteins involved in iodine metabolism in thyroid carcinomas.

F. Miot, B. Franc, S. Costagliola, 2003, The Journal of clinical endocrinology and metabolism.

Iodine-induced thyroid inhibition and cell necrosis: two consequences of the same free-radical mediated mechanism?

J. Denef, M. Many, M. V. Hove, 1996, Molecular and Cellular Endocrinology.

In vitro study of acute toxic effects of high iodide doses in human thyroid follicles.

C. Mestdagh, J. Denef, M. Many, 1992, Endocrinology.

Morphological and functional changes during thyroid hyperplasia and involution in C3H Mice: evidence for folliculoneogenesis during involution.

J. Denef, S. Haumont, M. Many, 1983, Endocrinology.

C. Mestdagh, P. Fragu, J. Denef, 1990, Cell and Tissue Research.

Morphological changes in mice thyroid induced by iodine deficiency

C. Beckers, J. Denef, S. Haumont, 1980, Virchows Archiv. B, Cell pathology including molecular pathology.

Two-step development of Hashimoto-like thyroiditis in genetically autoimmune prone non-obese diabetic mice: effects of iodine-induced cell necrosis.

H. Drexhage, J. Denef, M. Dardenne, 1995, The Journal of endocrinology.

Iodine deficiency-induced long lasting angiogenic reaction in thyroid cancers occurs via a VEGF-HIF-1, but not a ROS dependent pathway.

S. Baatout, I. Colin, J. Denef, 2012 .

Early occurrence of metastatic differentiated thyroid carcinomas in transgenic mice expressing the A2a adenosine receptor gene and the human papillomavirus type 16 E7 oncogene.

M. Parmentier, C. Ledent, J. Dumont, 1996, Oncogene.

Localization of a Band 3‐related protein in the mitochondria‐rich cells of amphibian skin epithelium

O. Devuyst, J. Denef, J. Crabbé, 1993, Biology of the cell.

Iodide deficiency-induced angiogenic stimulus in the thyroid occurs via HIF- and ROS-dependent VEGF-A secretion from thyrocytes.

I. Colin, J. Audinot, J. Denef, 2009, American journal of physiology. Endocrinology and metabolism.

Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase.

G Vassart, F Libert, M. Parmentier, 1995, The Biochemical journal.

High frequency of thymic ectopy in thyroids from autoimmune prone nonobese diabetic female mice.

H. Drexhage, J. Denef, M. Many, 1993, Laboratory investigation; a journal of technical methods and pathology.

Costimulation of Adenylyl Cyclase and Phospholipase C by a Mutantα 1B-Adrenergic Receptor Transgene Promotes Malignant Transformation of Thyroid Follicular Cells1.

M. Parmentier, R. Lefkowitz, C. Ledent, 1997, Endocrinology.

Morphological and functional changes during thyroid hyperplasia and involution in C3H mice: effects of iodine and 3,5,3'-triiodothyronine during involution.

C. Beckers, J. Denef, S. Haumont, 1985, Endocrinology.

Destruction of Contrast Microbubbles by Ultrasound: Effects on Myocardial Function, Coronary Perfusion Pressure, and Microvascular Integrity

G Van Camp, A. Pasquet, J. Melin, 2001, Circulation.

Relationships between cell division, expression of growth factors and microcirculation in the thyroids of Tg-A2aR transgenic mice and patients with Graves' disease.

C. Ledent, I. Colin, J. Denef, 2003, The Journal of endocrinology.

Antigoitrogenic effect of combined supplementation with dl- (cid:225) -tocopherol, ascorbic acid and (cid:226) -carotene and of dl- (cid:225) -tocopherol alone in the rat

I. Colin, J. Denef, M. Many, 1998 .

Morphometric studies of normal sural nerves in children

J. Denef, J F Denef, G Ferriere, 1985, Muscle & nerve.

Protein S-thiolation can mediate the inhibition of protein synthesis induced by tert-butyl hydroperoxide in isolated rat hepatocytes.

J. Denef, I. Latour, P. Buc Calderon, 1999, Toxicology and applied pharmacology.

Activation of Poly(ADP-Ribose)Polymerase in rat hepatocytes does not contribute to their cell death by oxidative stress.

J. Denef, I. Latour, P. Buc Calderon, 2000, Experimental cell research.

Pharmacokinetic Interactions between the Hepatitis C Virus Inhibitors Elbasvir and Grazoprevir and HIV Protease Inhibitors Ritonavir, Atazanavir, Lopinavir, and Darunavir in Healthy Volunteers

X. Chu, P. Jumes, J. Butterton, 2019, Antimicrobial Agents and Chemotherapy.

Automatic morphometry of nerve histological sections

C Veraart, O. Cuisenaire, C. Veraart, 2000, Journal of Neuroscience Methods.

Expression of the endothelin-1 gene in the rat thyroid gland and changes in its peptide and mRNA levels in goiter formation and iodide-induced involution.

I. Colin, J. Ketelslegers, T. Rebai, 1994, The Journal of endocrinology.

Nonrandom distribution of gap junctions between pancreatic beta-cells.

L Orci, L. Orci, P. Meda, 1980, The American journal of physiology.

Involvement of T cell immunity in the transient thyroid inflammation induced by iodide in goitrous BALB/C and nude mice.

T. Rebai, J. Denef, M. Many, 1994, Autoimmunity.

Renal effects of the high ceiling diuretic torasemide in rats and dogs.

J. Denef, A. Georges, J. Delarge, 1985, Arzneimittel-Forschung.

Pharmacokinetic Interactions Between the HCV Inhibitors Elbasvir and Grazoprevir and HIV Protease Inhibitors Ritonavir, Atazanavir, Lopinavir, or Darunavir in Healthy Participants

X. Chu, P. Jumes, J. Butterton, 2019 .

Selenium deficiency aggravates the necrotizing effects of a high iodide dose in iodine deficient rats.

J. Dumont, J. Denef, M. Many, 1993, Endocrinology.

Computer-assisted self-assessment (CASA) in histology

P. Gathy, Jean-François Denef, Stanislas Haumont, 1991 .

Pharmacokinetic and pharmacodynamic assessments of atogepant in healthy male adults: Results from phase 1 studies

Jialin Xu, C. Matthews, R. Boinpally, 2023, Cephalalgia Reports.

Effects of iodide and thyroxine on iodine-deficient mouse thyroid: a morphological and functional study.

C. Beckers, J. Denef, S. Haumont, 1986, Journal of Endocrinology.

Increased follicular heterogeneity in experimental colloid goiter produced by refeeding iodine excess after thyroid hyperplasia.

J. Denef, S. Haumont, M. Many, 1986, Endocrinology.

Cytochemical localization of hydrogen peroxide in isolated thyroid follicles.

J. Denef, U. Björkman, R. Ekholm, 1981, Journal of ultrastructure research.

What could mice tell us about goiter or other benign thyroid diseases?

J. Denef, M. Many, A. Gérard, 2009, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

Effects of an inhaled soluble guanylate cyclase (sGC) stimulator MK-5475 in pulmonary arterial hypertension (PAH).

E. Bajwa, J. Palcza, J. Denef, 2022, Respiratory Medicine.

Morphometry of nuclear pore complexes in thyroid cells during hyperplasia and involution

J. Denef, A. Cordier, S. Haumont, 1981, Molecular and Cellular Endocrinology.

N-acetylcysteine and 15 deoxy-{delta}12,14-prostaglandin J2 exert a protective effect against autoimmune thyroid destruction in vivo but not against interleukin-1{alpha}/interferon {gamma}-induced inhibitory effects in thyrocytes in vitro.

B. Decallonne, I. Colin, J. Denef, 2010, The American journal of pathology.

Costimulation of adenylyl cyclase and phospholipase C by a mutant alpha 1B-adrenergic receptor transgene promotes malignant transformation of thyroid follicular cells.

M. Parmentier, R. Lefkowitz, C. Ledent, 1997, Endocrinology.