J. Laï

发表

Chromosome 13 abnormalities identified by FISH analysis and serum beta2-microglobulin produce a powerful myeloma staging system for patients receiving high-dose therapy.

R. Bataille, J. Mary, P. Moreau, 2001, Blood.

Myeloid Cell Differentiation Arrest by Mir-125b-1 in Myelodysplasic Syndrome and Acute Myeloid Leukemia with the T(2;11)(p21;q23) Translocation

P. Brousset, C. Mecucci, G. Delsol, 2008 .

Frequency of structural abnormalities of the long arm of chromosome 12 in myelofibrosis with myeloid metaplasia.

P. Morel, F. Bauters, J. Andrieux, 2002, Cancer genetics and cytogenetics.

Genomic characterization of Imatinib resistance in CD34+ cell populations from chronic myeloid leukaemia patients.

B. Quesnel, C. Preudhomme, E. Lippert, 2011, Leukemia research.

Translocation t(10;17)(p13;q12) in two cases of acute nonlymphocytic leukemia with phagocytic activity of blasts. A new cytogenetic entity?

P. Fenaux, F. Bauters, J. Laï, 1989, Cancer genetics and cytogenetics.

Bone morphogenetic protein antagonist gene NOG is involved in myeloproliferative disease associated with myelofibrosis.

X. Leleu, J. Andrieux, P. Vandenberghe, 2007, Cancer genetics and cytogenetics.

High incidence of biallelic point mutations in the Runt domain of the AML1/PEBP2αB gene in Mo acute myeloid leukemia and in myeloid malignancies with acquired trisomy 21

E. Macintyre, C. Preudhomme, P. Fenaux, 2000 .

Two cases of t(1;16)(p11;p11) in multiple myeloma: confirmation by chromosome painting.

F. Bauters, T. Facon, M. Zandecki, 1994, Cancer genetics and cytogenetics.

Familial occurrence of thymoma and autoimmune diseases with the constitutional translocation t(14;20)(q24.1;p12.3)

M. Copin, J. Andrieux, B. Delobel, 2005, Genes, chromosomes & cancer.

High occurrence of JAK2 V617 mutation in refractory anemia with ringed sideroblasts associated with marked thrombocytosis

B. Quesnel, C. Preudhomme, F. Bauters, 2006, Leukemia.

Rare occurrence of P53 gene mutations in multiple myeloma

C. Preudhomme, P. Fenaux, M. Vanrumbeke, 1992, British journal of haematology.

Mutations of the P53 gene in acute myeloid leukaemia

R. Berger, C. Preudhomme, P. Fenaux, 1992, British journal of haematology.

TPA stimulation culture for improved detection of t(11;14)(q13;q32) in mantle cell lymphoma.

M. Copin, B. Quesnel, C. Preudhomme, 2002, Annales de genetique.

A report from the LALA-94 and LALA-SA groups on hypodiploidy with 30 to 39 chromosomes and near-triploidy: 2 possible expressions of a sole entity conferring poor prognosis in adult acute lymphoblastic leukemia (ALL).

A. Delannoy, A. Bernheim, C. Bastard, 2004, Blood.

Favorable cytogenetic abnormalities in secondary leukemia

P. Fenaux, F. Bauters, J. Laï, 1989, Cancer.

17p Deletion in acute myeloid leukemia and myelodysplastic syndrome. Analysis of breakpoints and deleted segments by fluorescence in situ.

C. Preudhomme, P. Fenaux, C. Roumier, 1998, Blood.

Cytogenetics in multiple myeloma: a multicenter study of 24 patients with t(11;14)(q13;q32) or its variant.

F. Vasseur, L. Michaux, F. Bauters, 1998, Cancer genetics and cytogenetics.

Mutations of the P53 Gene in Acute Leukemias: A Report on 207 Cases

C. Preudhomme, P. Fenaux, P. Jonveaux, 1994 .

Translocations (5;17) and (7;17) in patients with de novo or therapy-related myelodysplastic syndromes or acute nonlymphocytic leukemia. A possible association with acquired pseudo-Pelger-Huët anomaly and small vacuolated granulocytes.

P. Fenaux, F. Bauters, M. Zandecki, 1990, Cancer genetics and cytogenetics.

Abnormal Cytogenetics and Significant Bone Marrow Plasmacytosis are Predictive of Early Progression and Short Survival in Patients with Low Tumor Mass Asymptomatic Multiple Myeloma

B. Quesnel, F. Bauters, X. Leleu, 2004, Leukemia & lymphoma.

Acute myeloid leukemia and myelodysplastic syndromes following essential thrombocythemia treated with hydroxyurea: high proportion of cases with 17p deletion.

E. Wattel, C. Preudhomme, P. Fenaux, 1998, Blood.

Image analysis in multiple myeloma at diagnosis. Correlation with cytogenetic study.

F. Bauters, T. Facon, M. Zandecki, 1994, Cancer genetics and cytogenetics.

Karyotypic abnormalities in myelofibrosis following polycythemia vera.

F. Bauters, J. Andrieux, P. Agapé, 2003, Cancer genetics and cytogenetics.

de novo myelodysplastic syndromes in adults aged 50 or less. A report on 37 cases.

C. Preudhomme, P. Morel, P. Fenaux, 1990, Leukemia research.

Mutations in the p53 gene in myelodysplastic syndromes.

R. Berger, P. Fenaux, M. Goossens, 1991, Oncogene.

Long‐term follow‐up of de novo myelodysplastic syndromes treated with intensive chemotherapy: incidence of long‐term survivors and outcome of partial responders

E. Wattel, C. Preudhomme, P. Fenaux, 1997, British journal of haematology.

Fluorescence in situ hybridization characterization of ider(20q) in myelodysplastic syndrome

J. Andrieux, J. Laï, I. Plantier, 2008, British journal of haematology.

del(17p) in myeloid malignancies

C. Preudhomme, P. Fenaux, M. Zandecki, 2011 .

Mutations of the p53 gene in B-cell chronic lymphocytic leukemia: a report on 39 cases with cytogenetic analysis.

C. Preudhomme, P. Morel, P. Fenaux, 1992, Leukemia.

Clinics and pathology Disease Acute non lymphocytic leuemia / myelodysplastic syndromes

C. Preudhomme, P. Fenaux, M. Zandecki, 2011 .

Detection of minimal residual disease in chronic myeloid leukemia patients after bone marrow transplantation by polymerase chain reaction.

P. Fenaux, B. Grandchamp, J. Laï, 1990, Leukemia.

Cases With 17p Deletion Essential Thrombocythemia Treated With Hydroxyurea: High Proportion of Acute Myeloid Leukemia and Myelodysplastic Syndromes Following

C. Preudhomme, P. Fenaux, Y. Sterkers, 2013 .

Acute myeloid leukemia and myelodysplastic syndromes following essential thrombocythemia treated with hydroxyurea: high proportion of cases with 17p deletion.

E. Wattel, C. Preudhomme, P. Fenaux, 1998, Blood.

Cytogenetic studies and their prognostic significance in agnogenic myeloid metaplasia: a report on 47 cases.

R. Beuscart, P. Fenaux, F. Bauters, 1988, Blood.

Is there still a role for low-dose cytosine arabinoside in de novo acute myeloid leukemia in the elderly?

E. Wattel, P. Fenaux, F. Bauters, 1993, Annals of Hematology.

Is translocation (8;21) a "favorable" cytogenetic rearrangement in acute myeloid leukemia?

C. Preudhomme, P. Fenaux, F. Bauters, 1990, Nouvelle revue francaise d'hematologie.

Translocation t(1;19)(q23;p13) in acute lymphoblastic leukemia. A report on six new cases and an unusual t(17;19)(q11;q13), with special reference to prognostic factors.

P. Fenaux, F. Bauters, J. Laï, 1989, Cancer genetics and cytogenetics.

Coexistence of AML1/RUNX1 and BCR-ABL point mutations in an imatinib-resistant form of CML

I. Yakoub-Agha, C. Preudhomme, T. Facon, 2005, Leukemia.

Mechanisms of genesis of variant translocation in chronic myeloid leukemia are not correlated with ABL1 or BCR deletion status or response to imatinib therapy.

V. Eclache, J. Andrieux, J. Laï, 2008, Cancer genetics and cytogenetics.

RUNX1 DNA-binding mutations and RUNX1-PRDM16 cryptic fusions in BCR-ABL+ leukemias are frequently associated with secondary trisomy 21 and may contribute to clonal evolution and imatinib resistance.

C. Preudhomme, I. Tigaud, J. Laï, 2007, Blood.

FISH analysis with a YAC probe improves detection of LAZ3/BCL6 rearrangement in non-Hodgkin's lymphoma.

C. Bastard, C. Preudhomme, P. Fenaux, 2000, The hematology journal : the official journal of the European Haematology Association.

Good correlation between RT-PCR analysis and relapse in Philadelphia (Ph1)-positive acute lymphoblastic leukemia (ALL)

C. Preudhomme, P. Fenaux, M. Vanrumbeke, 1997, Leukemia.

p16INK4a immunocytochemical analysis is an independent prognostic factor in childhood acute lymphoblastic leukemia

B. Quesnel, P. Fenaux, F. Bauters, 2002 .

Promyelocytic blast crisis of Philadelphia-positive thrombocythemia with translocations (9;22) and (15;17).

P. Fenaux, F. Bauters, M. Zandecki, 1987, Cancer genetics and cytogenetics.

Investigation of minimal residual disease in adult Ph1 positive acute lymphoblastic leukemia by a combination of cell sorting and fluorescence in situ hybridization: a preliminary study on 6 cases.

C. Preudhomme, P. Fenaux, J. Laï, 2000, Haematologica.

C6) Mutations of the P53 gene in myelodysplastic syndromes (MDS). A report on 152 cases

R. Berger, C. Preudhomme, P. Fenaux, 1991 .

Dysregulation and overexpression of HMGA2 in myelofibrosis with myeloid metaplasia

F. Bauters, J. Andrieux, C. Roumier, 2004, Genes, chromosomes & cancer.

Reassessment of an apparent t(12;17)(p11;p11) as an unbalanced t(17;21)(p11;q11) in a case of B-cell chronic lymphocytic leukemia by fluorescence in situ hybridization.

P. Fenaux, J. Laï, M. Flactif, 1994, Cancer genetics and cytogenetics.

JAK2V617F-positive polycythemia vera and Philadelphia chromosome-positive chronic myeloid leukemia: one patient with two distinct myeloproliferative disorders

C. Preudhomme, Aline Renneville, C. Rose, 2008, Leukemia.

Hypereosinophilia with abnormal T cells, trisomy 7 and elevated TARC serum level.

M. Capron, K. Ghomari, J. Laï, 2003, Haematologica.

Cytogénétique Hématologique (GFCH) d'Hématologie Cellulaire (GFHC) and the Groupe Français de gene mutations: a report of 59 cases by the Groupe Français M0 AML, clinical and biologic features of the disease, includingAML1

O. Casasnovas, E. Macintyre, R. Berger, 2013 .

Cryptic and partial deletions of PRDM16 and RUNX1 without t(1;21)(p36;q22) and/or RUNX1–PRDM16 fusion in a case of progressive chronic myeloid leukemia: A complex chromosomal rearrangement of underestimated frequency in disease progression?

C. Preudhomme, J. Laï, C. Roche-Lestienne, 2008, Genes, chromosomes & cancer.

ETV6 is the target of chromosome 12p deletions in t(12;21) childhood acute lymphocytic leukemia

H. Cavé, C. Preudhomme, B. Grandchamp, 1997, Leukemia.

Cryptic 6p21.3 duplications and triplication involving HMGA1 partially masked by add 6p in four cases of myelodysplasia.

F. Bauters, J. Andrieux, N. Dastugue, 2006, Cancer genetics and cytogenetics.

Transient leukemoid disorder in a newborn with Down syndrome followed 19 months later by an acute myeloid leukemia: demonstration of the same structural change in both instances with clonal evolution.

F. Geneviève, M. Zandecki, J. Laï, 1999, Cancer genetics and cytogenetics.

Translocation (3;13)(q27;q14): a nonrandom and probably secondary structural change in non-Hodgkin lymphomas.

P. Morel, P. Fenaux, F. Bauters, 1998, Cancer genetics and cytogenetics.

Chronic myeloid leukemia with unusual variant Ph translocation (22;22)(q11;q13). Two cases with chimeric BCR-ABL transcripts.

P. Fenaux, B. Grandchamp, J. Laï, 1990, Cancer genetics and cytogenetics.

[Cytogenetics of myelodysplastic syndromes].

P. Fenaux, J. Laï, 1997, Pathologie-biologie.

Translocation (1;7) in a case of secondary chronic myelomonocytic leukemia.

P. Fenaux, F. Bauters, J. Laï, 1987, Cancer genetics and cytogenetics.

Chronic myelogenous leukemia with translocation (8;22): report of a new case.

F. Bauters, J. Laï, J. Jouet, 1985, Cancer genetics and cytogenetics.

Four cases of follicular lymphoma with t(14;18)(q32;q21) and t(3;4)(q27;p13) with LAZ3 (BCL6) rearrangement.

P. Morel, J. Laï, S. Galiègue‐Zouitina, 1999, Cancer genetics and cytogenetics.

Interphase fluorescence in situ hybridization (FISH) as a powerful tool for the detection of aneuploidy in multiple myeloma.

F. Bauters, T. Facon, M. Zandecki, 1995, Leukemia.

Acute myeloid leukemia and myelodysplastic syndromes following essential thrombocythemia treated with hydroxyurea: high proportion of cases with 17p deletion.

E. Wattel, C. Preudhomme, P. Fenaux, 1998, Blood.

P53 gene mutations in acute myeloid leukemia with 17p monosomy.

R. Berger, P. Fenaux, P. Jonveaux, 1991, Blood.

Several cytogenetic subclones may be identified within plasma cells from patients with monoclonal gammopathy of undetermined significance, both at diagnosis and during the indolent course of this condition.

F. Bauters, T. Facon, F. Geneviève, 1997, Blood.

Chromosomal insertion involving MLL in childhood acute myeloblastic leukemia (M4).

C. Preudhomme, J. Andrieux, J. Laï, 2004, Cancer genetics and cytogenetics.

Several types of mutations of the Abl gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment.

Claude Preudhomme, Pierre Fenaux, C. Preudhomme, 2002, Blood.

Nonrandom 4p13 rearrangements of the RhoH/TTF gene, encoding a GTP-binding protein, in non-Hodgkin's lymphoma and multiple myeloma

C. Preudhomme, P. Fenaux, F. Bauters, 2000, Oncogene.

Acute lymphocytic leukemia with 9p anomalies. A report of four additional cases and review of the literature.

P. Fenaux, J. Laï, M. Estienne, 1988, Cancer genetics and cytogenetics.

A mutation conferring resistance to imatinib at the time of diagnosis of chronic myelogenous leukemia.

C. Preudhomme, T. Facon, J. Laï, 2003, The New England journal of medicine.

Molecular characterization of the idiopathic hypereosinophilic syndrome (HES) in 35 French patients with normal conventional cytogenetics

B. Quesnel, C. Preudhomme, P. Fenaux, 2005, Leukemia.

Improved cytogenetics in multiple myeloma: a study of 151 patients including 117 patients at diagnosis.

J. Mary, P. Morel, F. Bauters, 1995, Blood.

High incidence of cryptic translocations involving the Ig heavy chain gene in multiple myeloma, as shown by fluorescence in situ hybridization

R. Bataille, Jian-yong Li, H. Avet-Loiseau, 1999, Genes, chromosomes & cancer.

Dicentric (9;12) in acute lymphocytic leukemia and other hematological malignancies: report from a dic(9;12) study group.

J. Huret, F. Lampert, C. Charrin, 1995, Leukemia.

Chronic myeloproliferative disorder with t(8;22)(p11;q11) can mime clonal cytogenetic evolution of authentic chronic myelogeneous leukemia

C. Preudhomme, Aline Renneville, J. Laï, 2008, Genes, chromosomes & cancer.

Role of multiplex FISH in identifying chromosome involvement in myelodysplastic syndromes and acute myeloid leukemias with complex karyotypes: a report on 28 cases.

C. Preudhomme, P. Fenaux, C. Roumier, 2005, Cancer genetics and cytogenetics.

Involvement of peripheral blood cells in multiple myeloma: chromosome changes are the rule within circulating plasma cells but not within B lymphocytes.

C. Preudhomme, F. Bauters, T. Facon, 1997, Leukemia.

MULTIPLE MYELOMA: ALMOST ALL PATIENTS ARE CYTOGENETICALLY ABNORMAL

T. Facon, M. Zandecki, J. Laï, 1996, British journal of haematology.

receiving high-dose therapy 2-microglobulin produce a powerful myeloma staging system for patients β Chromosome 13 abnormalities identified by FISH analysis and serum

R. Bataille, J. Mary, P. Moreau, 2013 .

Factors predicting molecular and cytogenetic response in chronic myeloid leukemia patients treated with imatinib.

C. Preudhomme, T. Facon, J. Laï, 2005, Haematologica.

Cytogenetics and their prognostic value in de novo acute myeloid leukaemia: a report on 283 cases

R. Beuscart, C. Preudhomme, P. Morel, 1989, British journal of haematology.

Nonrandom fusion of L‐Plastin(LCP1) and LAZ3(BCL6) genes by t(3;13)(q27;q14) chromosome translocation in two cases of B‐cell non‐Hodgkin lymphoma

J. Laï, S. Galiègue‐Zouitina, Sylvie Galiègue‐Zouitina, 1999, Genes, chromosomes & cancer.

Acute megakaryoblastic leukemia with der(7)t(5;7)(q11;p11∼p12) associated with Down syndrome: a fourth case report

J. Andrieux, N. Dastugue, J. Laï, 2006 .

De novo myelodysplastic syndrome (MDS) with deletion of the long arm of chromosome 20: a subtype of MDS with distinct hematological and prognostic features?

E. Wattel, C. Preudhomme, P. Morel, 1993, Leukemia research.

A Retrospective 20-Year Survey of the Incidence of Chronic Myeloid Leukemia in the Northern France Region.

C. Preudhomme, T. Facon, J. Laï, 2006 .

Isolated tetrasomy 8 in AML, MDS and MPD

O. Nibourel, J. Laï, C. Roche-Lestienne, 2011 .

Evaluation of minimal residual disease by interphase FISH in multiple myeloma: does complete remission exist?

F. Bauters, T. Facon, F. Geneviève, 1999, Leukemia.

Short communication Frequency of structural abnormalities of the long arm of chromosome 12 in myelofibrosis with myeloid metaplasia

P. Morel, F. Bauters, J. Andrieux, 2002 .

[Partial trisomy 12 and 8 with mosaicism, associated with translocation t(8;12) (p21;q13)].

J. Laï, M. Deminatti, J. Cousin, 1977, Annales de genetique.

Identification of a YAC spanning the translocation breakpoint t(8;22) associated with acute monocytic leukemia

D. Birnbaum, J. Fletcher, C. Preudhomme, 1996, Genes, chromosomes & cancer.

Hyperdiploid karyotypes in acute myeloid leukemia define a novel entity: a study of 38 patients from the Groupe Francophone de Cytogenetique Hematologique (GFCH)

F. Speleman, R. Berger, E. Lippert, 2008, Leukemia.

11 Glutathione S transferase theta 1 (GSTT1) gene defects in myelodysplastic syndromes (MDS) and their correlation with Kryotype and exposure to potential carcinogens

C. Preudhomme, P. Fenaux, M. Vanrumbeke, 1997 .

MDS and AML with 17p deletion are associated to specific dysgranulopoiesis and a high incidence of p53 mutations

E. Wattel, C. Preudhomme, P. Fenaux, 1994 .

Three cases of translocation (8;16)(p11;p13) observed in acute myelomonocytic leukemia: a new specific subgroup?

F. Bauters, M. Zandecki, J. Laï, 1987, Cancer genetics and cytogenetics.

ider(20q) in Myeloid Malignancies

J. Andrieux, J. Laï, N. Douet-Guilbert, 2011 .

Isoderivative of deleted chromosome 20 in primary myelofibrosis (PMF) characterized by molecular cytogenetics and array CGH

V. Ugo, J. Andrieux, J. Laï, 2009, Annals of Hematology.

Patterns of genomic aberrations suggest that Burkitt lymphomas with complex karyotype are distinct from other aggressive B‐cell lymphomas with MYC rearrangement

A. Hagemeijer, L. Michaux, E. Lippert, 2013, Genes, chromosomes & cancer.

Congenital acute monoblastic leukemia with double translocation (8;16) (p11;p13) and (16;20) (q13;p13).

M. Zandecki, J. Laï, O. Chassaing, 1988, Nouvelle revue francaise d'hematologie.

Three new cases of non-Hodgkin lymphoma with t(9;14)(p13;q32).

M. Copin, B. Quesnel, F. Bauters, 2003, Cancer genetics and cytogenetics.

Leukemia : Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K

F. Speleman, R. Berger, E. Lippert, 2008 .

Prognostic factors in agnogenic myeloid metaplasia: a report on 195 cases with a new scoring system.

P. Morel, F. Bauters, J. Laï, 1996, Blood.

Disruption and aberrant expression of HMGA2 as a consequence of diverse chromosomal translocations in myeloid malignancies

M. Odero, M. Calasanz, J. Vizmanos, 2005, Leukemia.

Kinetic of chronic myeloid leukaemia (CML) prevalence in Northern France since the introduction of imatinib

C. Preudhomme, T. Facon, J. Laï, 2008 .

Cytogenetic analysis has strong independent prognostic value in de novo myelodysplastic syndromes and can be incorporated in a new scoring system: a report on 408 cases.

A. Duhamel, E. Wattel, C. Preudhomme, 1993, Leukemia.

Study of the Rearrangement of Proto-oncogene MET in 88 Cases of Myelodysplastic Syndromes

P. Fenaux, F. Bauters, J. Laï, 1992 .

Myelodysplastic syndromes and acute myeloid leukemia with 17p deletion. An entity characterized by specific dysgranulopoïesis and a high incidence of P53 mutations.

E. Wattel, C. Preudhomme, P. Fenaux, 1995, Leukemia.

H. Tilly, B. Quesnel, E. Archimbaud, 1993, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Clinical significance of p53 mutations in newly diagnosed Burkitt's lymphoma and acute lymphoblastic leukemia: a report of 48 cases.

E. Wattel, C. Preudhomme, B. Hecquet, 1995, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Genome Wide SNP Analysis Reveals Frequent Cryptic Clonal Chromosomal Aberrations Including Uniparental Disomy (UPD) in Waldenstrom's Macroglobulinemia.

C. Preudhomme, P. Morel, X. Leleu, 2009 .

Chronic myelogenous leukemia with t(9;22) and t(8;11): a new chromosome anomaly.

P. Fenaux, F. Bauters, J. Laï, 1987, Cancer genetics and cytogenetics.

Mutations of the p53 gene in B-cell lymphoblastic acute leukemia: a report on 60 cases.

R. Berger, C. Preudhomme, P. Fenaux, 1992, Leukemia.

Polymorphism of the proto-oncogene ETS-1 in hematological malignancies.

B. Debuire, P. Morel, P. Fenaux, 1990, Leukemia.

C. Lorthois, C. Preudhomme, P. Fenaux, 1991, Leukemia & lymphoma.

Prognostic value of real-time quantitative PCR (RQ-PCR) in AML with t(8;21)

C. Preudhomme, P. Fenaux, F. Bauters, 2005, Leukemia.

Prognostic factors in adult chronic myelomonocytic leukemia: an analysis of 107 cases.

R. Beuscart, P. Fenaux, F. Bauters, 1988, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

RUNX1 DNA-binding mutations and RUNX1-PRDM16 cryptic fusions in BCR-ABL+ leukemias are frequently associated with secondary trisomy 21 and may contribute to clonal evolution and imatinib resistance.

C. Preudhomme, I. Tigaud, J. Laï, 2007, Blood.

Early paternity and relapse after bone marrow transplantation

P. Fenaux, F. Bauters, T. Facon, 1993, American journal of hematology.

Cytogenetic studies in 30 patients with Burkitt's lymphoma or L3 acute lymphoblastic leukemia with special reference to additional chromosome abnormalities.

P. Fenaux, M. Zandecki, J. Laï, 1989, Annales de genetique.

Cytogenetic studies and their prognostic significance in agnogenic myeloid metaplasia: a report on 47 cases.

P. Fenaux, F. Bauters, J. Laï, 1988, Blood.