J. Krueger

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Intraepidermal lymphocytes in psoriatic lesions are activated GMP‐17(TIA‐1)+CD8+CD3+ CTLs as determined by phenotypic analysis

R. Steinman, N. Bhardwaj, L. Austin, 1998, Journal of cutaneous pathology.

Multiple Proinflammatory Pathways in TNF Inhibition Rapidly Down-Regulates

J. Krueger, Francesca Chamian, S. Masud, 2005 .

TNF Inhibition Rapidly Down-Regulates Multiple Proinflammatory Pathways in Psoriasis Plaques1

A. Gottlieb, J. Krueger, Francesca Chamian, 2005, The Journal of Immunology.

Psoriasis vulgaris: an interplay of T lymphocytes, dendritic cells, and inflammatory cytokines in pathogenesis

J. Krueger, Francesca Chamian, 2004, Current opinion in rheumatology.

Molecular Profiling of Immune Activation Associated with Regression of Melanoma Metastases Induced by Diphencyprone.

D. Coit, M. Suárez-Fariñas, J. Krueger, 2016, The Journal of investigative dermatology.

A Randomized, Placebo-Controlled Study of SRT2104, a SIRT1 Activator, in Patients with Moderate to Severe Psoriasis

C. Leonardi, M. Suárez-Fariñas, D. Shortino, 2015, PloS one.

Digital imaging biomarkers feed machine learning for melanoma screening

Daniel S. Gareau, James G. Krueger, John A. Carucci, 2016, Experimental dermatology.

Differences in the responsiveness of splenic, lymph node, and peripheral blood lymphoid cells to tumor membrane extracts.

R. Segal, J. Krueger, R. Moyer, 1977, Cancer research.

Immune and barrier characterization of atopic dermatitis skin phenotype in Tanzanian patients.

P. Schmid‐Grendelmeier, Ning Zhang, J. Krueger, 2021, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Risankizumab compared with adalimumab in patients with moderate-to-severe plaque psoriasis (IMMvent): a randomised, double-blind, active-comparator-controlled phase 3 trial

E. H. Thompson, M. Gooderham, K. Reich, 2019, The Lancet.

High inflammation in HS extends to perilesional skin, and can be subdivided by LCN2 expression.

J. Krueger, Hong Hur, S. Garcet, 2021, The Journal of allergy and clinical immunology.

Topical, systemic and biologic therapies in hidradenitis suppurativa: pathogenic insights by examining therapeutic mechanisms

J. Krueger, J. Frew, J. Hawkes, 2019, Therapeutic advances in chronic disease.

Analytical approaches to reporting long-term clinical trial data

K. Wittkowski, K. Papp, J. Krueger, 2008, Current medical research and opinion.

Psoriasis: evolution of pathogenic concepts and new therapies through phases of translational research

J. Krueger, E. Guttman‐Yassky, E. Guttman-Yassky, 2007, The British journal of dermatology.

Sunlight-induced basal cell carcinoma tumor cells and ultraviolet-B-irradiated psoriatic plaques express Fas ligand (CD95L).

B. Nickoloff, J. Krueger, T. Wrone-Smith, 1998, The Journal of clinical investigation.

312-nanometer Ultraviolet B Light (Narrow-Band UVB) Induces Apoptosis of T Cells within Psoriatic Lesions

L. Austin, J. Krueger, I. Cardinale, 1999, The Journal of experimental medicine.

The immunogenetics of Psoriasis: A comprehensive review.

A. Bowcock, J. Krueger, J. Harden, 2015, Journal of autoimmunity.

Psoriasis pathophysiology: current concepts of pathogenesis

A. Bowcock, J. Krueger, 2005, Annals of the rheumatic diseases.

Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis.

G. Yancopoulos, M. Suárez-Fariñas, N. Graham, 2014, The Journal of allergy and clinical immunology.

Atopic dermatitis and skin disease Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis

G. Yancopoulos, N. Graham, G. Pirozzi, 2022 .

Quantifying the natural variation in lesion counts over time in untreated hidradenitis suppurativa: Implications for outcome measures and trial design

Caroline S. Jiang, R. Vaughan, J. Krueger, 2020, JAAD international.

Gene profiling of narrowband UVB-induced skin injury defines cellular and molecular innate immune responses.

M. Suárez-Fariñas, J. Krueger, M. Lowes, 2013, The Journal of investigative dermatology.

Expression of cellular-yes protein in mammalian tissues.

M. Sudol, Y. Zhao, J. Krueger, 1990, Oncogene.

The inflammatory proteome of hidradenitis suppurativa skin is more expansive than that of psoriasis vulgaris.

J. Krueger, S. Garcet, K. Navrazhina, 2021, Journal of the American Academy of Dermatology.

Aberrant connective tissue differentiation towards cartilage and bone underlies human keloids in African Americans

M. Suárez-Fariñas, J. Krueger, S. Garcet, 2017, Experimental dermatology.

The immunologic basis for the treatment of psoriasis with new biologic agents.

J. Krueger, 2002, Journal of the American Academy of Dermatology.

Resident and "inflammatory" dendritic cells in human skin.

Lisa C. Zaba, J. Krueger, M. Lowes, 2009, The Journal of investigative dermatology.

Etanercept induces apoptosis of dermal dendritic cells in psoriatic plaques of responding patients.

A. Gottlieb, J. Krueger, M. Magliocco, 2006, Journal of the American Academy of Dermatology.

Ichthyosis molecular fingerprinting shows profound TH17 skewing and a unique barrier genomic signature

A. Paller, Margaret Chou, H. Wen, 2019, The Journal of allergy and clinical immunology.

Endogenous Growth Factor Pathways May Regulate Epidermal Hyperplasia in Chronic Venous Wounds: Modulation by Hydrocolloid Dressings

A. Gottlieb, B. Smoller, L. Staiano‐Coico, 1995 .

IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment

Charles H. Yoon, A. Regev, O. Troyanskaya, 2017, Cell.

Subcellular localization of pp60src in RSV-transformed cells.

J. Krueger, E. Garber, A. R. Goldberg, 1983, Current topics in microbiology and immunology.

Frontal fibrosing alopecia shows robust T helper 1 and Janus kinase 3 skewing

Ning Zhang, R. Paus, R. Phelps, 2020, The British journal of dermatology.

Lesional dendritic cells in patients with chronic atopic dermatitis and psoriasis exhibit parallel ability to activate T-cell subsets.

J. Carucci, M. Suárez-Fariñas, J. Krueger, 2011, The Journal of allergy and clinical immunology.

Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis

J. Silverberg, G. Yancopoulos, A. Menter, 2019, The Journal of allergy and clinical immunology.

Baseline IL‐22 expression in patients with atopic dermatitis stratifies tissue responses to fezakinumab

M. Lebwohl, A. Neumann, H. Wen, 2019, The Journal of allergy and clinical immunology.

Use of Tape Strips to Detect Immune and Barrier Abnormalities in the Skin of Children With Early-Onset Atopic Dermatitis.

A. Paller, J. Krueger, E. Guttman‐Yassky, 2019, JAMA dermatology.

Atopic dermatitis endotypes and implications for targeted therapeutics.

J. Krueger, E. Guttman‐Yassky, H. He, 2019, The Journal of allergy and clinical immunology.

A systematic review and critical evaluation of inflammatory cytokine associations in hidradenitis suppurativa

J. Krueger, J. Frew, J. Hawkes, 2018, F1000Research.

A systematic review and critical evaluation of immunohistochemical associations in hidradenitis suppurativa

J. Krueger, J. Frew, J. Hawkes, 2018, F1000Research.

A systematic review and critical evaluation of immunohistochemical associations in hidradenitis suppurativa

J. Krueger, J. Frew, J. Hawkes, 2018, F1000Research.

Atopic dermatitis and psoriasis: two different immune diseases or one spectrum?

J. Krueger, E. Guttman‐Yassky, E. Guttman-Yassky, 2017, Current opinion in immunology.

Reversal of atopic dermatitis with narrow-band UVB phototherapy and biomarkers for therapeutic response.

A. Bowcock, S. Duan, M. Suárez-Fariñas, 2011, The Journal of allergy and clinical immunology.

Residual genomic signature of atopic dermatitis despite clinical resolution with narrow-band UVB.

M. Suárez-Fariñas, J. Krueger, I. Cardinale, 2013, The Journal of allergy and clinical immunology.

The translational revolution and use of biologics in patients with inflammatory skin diseases.

J. Krueger, S. Noda, E. Guttman‐Yassky, 2015, The Journal of allergy and clinical immunology.

Skin-homing and systemic T-cell subsets show higher activation in atopic dermatitis versus psoriasis.

M. Suárez-Fariñas, J. Krueger, J. Fuentes-Duculan, 2015, The Journal of allergy and clinical immunology.

Early pediatric atopic dermatitis shows only a cutaneous lymphocyte antigen (CLA)(+) TH2/TH1 cell imbalance, whereas adults acquire CLA(+) TH22/TC22 cell subsets.

A. Paller, M. Suárez-Fariñas, J. Krueger, 2015, The Journal of allergy and clinical immunology.

Extensive alopecia areata is reversed by IL-12/IL-23p40 cytokine antagonism.

M. Lebwohl, M. Suárez-Fariñas, G. Singer, 2016, The Journal of allergy and clinical immunology.

A mild topical steroid leads to progressive anti-inflammatory effects in the skin of patients with moderate-to-severe atopic dermatitis.

M. Suárez-Fariñas, J. Krueger, S. Garcet, 2016, The Journal of allergy and clinical immunology.

Efficacy and safety of ustekinumab treatment in adults with moderate‐to‐severe atopic dermatitis

M. Suárez-Fariñas, J. Krueger, S. Garcet, 2017, Experimental dermatology.

Human keratinocytes are a major source of cutaneous platelet-derived growth factor.

J. Olerud, J. Krane, J. Krueger, 1993, The Journal of clinical investigation.

Effect of therapeutic integrin (CD11a) blockade with efalizumab on immune responses to model antigens in humans: results of a randomized, single blind study.

H. Ochs, P. Patel, J. Krueger, 2008, The Journal of investigative dermatology.

Alefacept (anti-CD2) causes a selective reduction in circulating effector memory T cells (Tem) and relative preservation of central memory T cells (Tcm) in psoriasis

K. Wittkowski, J. Krueger, Francesca Chamian, 2007, Journal of Translational Medicine.

Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris.

K. Wittkowski, J. Krueger, Francesca Chamian, 2005, Proceedings of the National Academy of Sciences of the United States of America.

PUVA bath therapy strongly suppresses immunological and epidermal activation in psoriasis: a possible cellular basis for remittive therapy

A. Gottlieb, J. Krueger, P. Gilleaudeau, 1994, The Journal of experimental medicine.

Basic and Translational Science: A Report from the GRAPPA 2016 Annual Meeting

B. Kirkham, C. Ritchlin, J. Krueger, 2017, The Journal of Rheumatology.

TNF-alpha Down-Regulates Filaggrin and Loricrin Through c-Jun N-Terminal Kinase: Role for TNF Antagonists to Improve Skin Barrier

M. Boguniewicz, E. Guttman, D. Leung, 2011 .

Effects of etanercept are distinct from infliximab in modulating proinflammatory genes in activated human leukocytes.

J. Krueger, I. Cardinale, A. Haider, 2007, The journal of investigative dermatology. Symposium proceedings.

Tyrosine Kinase 2 and Janus Kinase‒Signal Transducer and Activator of Transcription Signaling and Inhibition in Plaque Psoriasis.

I. McInnes, A. Blauvelt, J. Krueger, 2021, Journal of the American Academy of Dermatology.

Dominant Th1 and minimal Th17 skewing in discoid lupus revealed by transcriptomic comparison with psoriasis

M. Suárez-Fariñas, A. Franks, J. Krueger, 2013, The Journal of investigative dermatology.

A phase I, randomized, double‐blind study to assess the safety, tolerability and efficacy of the topical RORC2 inverse agonist PF‐06763809 in participants with mild‐to‐moderate plaque psoriasis

K. Beaumont, W. Wigger‐Alberti, C. Banfield, 2020, Clinical and experimental dermatology.

RNA Sequencing Keloid Transcriptome Associates Keloids With Th2, Th1, Th17/Th22, and JAK3-Skewing

Ning Zhang, J. Krueger, I. Cueto, 2020, Frontiers in Immunology.

Impact of Zostavax Vaccination on T-Cell Accumulation and Cutaneous Gene Expression in the Skin of Older Humans After Varicella Zoster Virus Antigen–Specific Challenge

N. Mabbott, E. S. Chambers, A. Akbar, 2018, The Journal of infectious diseases.

The Characterization of Varicella Zoster Virus-Specific T Cells in Skin and Blood during Aging.

Sarah E. Jackson, G. Ogg, F. Nestle, 2015, The Journal of investigative dermatology.

Tildrakizumab (MK‐3222), an anti‐interleukin‐23p19 monoclonal antibody, improves psoriasis in a phase IIb randomized placebo‐controlled trial

A. Gottlieb, H. Nakagawa, K. Papp, 2015, The British journal of dermatology.

The insulin-like growth factor 1 receptor is expressed by epithelial cells with proliferative potential in human epidermis and skin appendages: correlation of increased expression with epidermal hyperplasia.

A. Gottlieb, J. Krueger, E. Hodak, 1996, The Journal of investigative dermatology.

TNF-α Antagonist and Vascular Inflammation in Patients with Psoriasis Vulgaris: A Randomized Placebo-Controlled Study.

J. Tardif, M. Guertin, R. Bissonnette, 2017, The Journal of investigative dermatology.

Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways

C. Workman, T. Litman, S. Tian, 2015, BMC Medical Genomics.

HMB‐45 monoclonal antibody recognizes an inducible and reversible melanocyte cytoplasmic protein

B. Smoller, J. Krueger, A. Hsu, 1991, Journal of cutaneous pathology.

Cytokines in breast cancer cell dyshesion

J. Krueger, I. Cardinale, I. Tamm, 1998 .

Blockade of T Lymphocyte Costimulation with Cytotoxic T Lymphocyte–Associated Antigen 4–Immunoglobulin (Ctla4ig) Reverses the Cellular Pathology of Psoriatic Plaques, Including the Activation of Keratinocytes, Dendritic Cells, and Endothelial Cells

M. Lebwohl, P. Linsley, Sewon Kang, 2000, The Journal of experimental medicine.

CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris.

M. Lebwohl, P. Linsley, H. Ochs, 1999, The Journal of clinical investigation.

Human keratinocytes' response to injury upregulates CCL20 and other genes linking innate and adaptive immunity

M. Suárez-Fariñas, H. Mitsui, J. Krueger, 2011, The Journal of investigative dermatology.

Deficient Cutaneous Antibacterial Competence in Cutaneous T-Cell Lymphomas: Role of Th2-Mediated Biased Th17 Function

H. Volk, W. Sterry, R. Sabat, 2014, Clinical Cancer Research.

Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism

P. Puigserver, R. Clark, T. Kupper, 2017, Nature.

Pathogenesis and therapy of psoriasis

James G. Krueger, Anne M. Bowcock, A. Bowcock, 2007, Nature.

Interleukin-17 Inhibition for the Treatment of Inflammatory Skin Disease

J. Krueger, J. Hawkes, Jose A. Gonzalez, 2018 .

Discovery of the IL-23/IL-17 Signaling Pathway and the Treatment of Psoriasis

J. Krueger, T. C. Chan, J. Hawkes, 2018, The Journal of Immunology.

Autoantigens ADAMTSL5 and LL37 are significantly upregulated in active Psoriasis and localized with keratinocytes, dendritic cells and other leukocytes

J. Krueger, S. Garcet, J. Fuentes-Duculan, 2017, Experimental dermatology.

Molecular and Cellular Profiling of Scalp Psoriasis Reveals Differences and Similarities Compared to Skin Psoriasis

M. Suárez-Fariñas, J. Krueger, J. Ruano, 2016, PloS one.

Increased expression of interleukin‐17 pathway genes in nonlesional skin of moderate‐to‐severe psoriasis vulgaris

S. Tian, M. Suárez-Fariñas, J. Krueger, 2016, The British journal of dermatology.

The tryptophan metabolism enzyme L-kynureninase is a novel inflammatory factor in psoriasis and other inflammatory diseases.

M. Suárez-Fariñas, D. Gareau, J. Krueger, 2016, The Journal of allergy and clinical immunology.

Increased expression of IL-17 pathway genes in non-lesional skin of moderate-to-severe psoriasis vulgaris Short title : psoriasis features in non-lesional skin

S. Tian, M. Suárez-Fariñas, J. Krueger, 2015 .

Guselkumab (an IL-23-specific mAb) demonstrates clinical and molecular response in patients with moderate-to-severe psoriasis.

Y. Wasfi, C. Leonardi, Katherine Li, 2014, The Journal of allergy and clinical immunology.

Post-Therapeutic Relapse of Psoriasis after CD11a Blockade Is Associated with T Cells and Inflammatory Myeloid DCs

M. Suárez-Fariñas, J. Krueger, M. Lowes, 2012, PloS one.

IL-17A is Essential for Cell Activation and Inflammatory Gene Circuits in Psoriasis

P. Haslett, Artemis, G. Cameron, 2012 .

Apilimod Inhibits the Production of IL-12 and IL-23 and Reduces Dendritic Cell Infiltration in Psoriasis

A. Gottlieb, J. Barsoum, J. Chu, 2012, PloS one.

Anti-cytokine therapies for psoriasis.

J. Krueger, K. Nograles, 2011, Experimental cell research.

Altered expression of keratinocyte growth factor and its receptor in psoriasis.

P. Finch, J. Krueger, I. Cardinale, 1997, The American journal of pathology.

A Randomized Open Label Clinical Trial of Lipid-Lowering Therapy in Psoriasis to Reduce Vascular Endothelial Inflammation.

E. Fisher, A. Neimann, J. Berger, 2021, The Journal of investigative dermatology.

Cardiovascular Risk in Patients With Psoriasis: JACC Review Topic of the Week.

J. Berger, N. Ward, J. Krueger, 2021, Journal of the American College of Cardiology.

Cardiovascular Risk in Patients with Psoriasis

Jeffrey, N. Ward, J. Krueger, 2021 .

Lipoprotein Metabolism and Inflammation in Patients With Psoriasis.

E. Armstrong, J. Krueger, 2016, The American journal of cardiology.

CD200 upregulation in vascular endothelium surrounding cutaneous squamous cell carcinoma.

J. Carucci, D. Felsen, M. Suárez-Fariñas, 2013, JAMA dermatology.

Myeloid dendritic cells from human squamous cell carcinoma are poor stimulators of T cell proliferation

Lisa C. Zaba, Dariush Moussai, M. Suárez-Fariñas, 2010 .

Myeloid dendritic cells from human cutaneous squamous cell carcinoma are poor stimulators of T-cell proliferation.

J. Carucci, Lisa C. Zaba, Dariush Moussai, 2009, The Journal of investigative dermatology.

The human cutaneous squamous cell carcinoma microenvironment is characterized by increased lymphatic density and enhanced expression of macrophage-derived VEGF-C.

J. Carucci, Dariush Moussai, M. Suárez-Fariñas, 2011, The Journal of investigative dermatology.

Psoriasis pathogenesis and the development of novel targeted immune therapies

J. Krueger, T. C. Chan, J. Hawkes, 2017, The Journal of allergy and clinical immunology.

The molecular features of normal and atopic dermatitis skin in infants, children, adolescents and adults.

A. Paller, Ning Zhang, J. Krueger, 2021, The Journal of allergy and clinical immunology.

Tape strips from early‐onset pediatric atopic dermatitis highlight disease abnormalities in nonlesional skin

A. Paller, Ning Zhang, J. Krueger, 2020, Allergy.

Atopic dermatitis in African American patients is TH2/TH22-skewed with TH1/TH17 attenuation.

Ning Zhang, J. Krueger, J. Fuentes-Duculan, 2019, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Alopecia areata is characterized by expansion of circulating Th2/Tc2/Th22, within the skin‐homing and systemic T‐cell populations

H. Wen, J. Krueger, E. Guttman‐Yassky, 2018, Allergy.

Tc 2 cells are associated with alopecia areata severity

H. Wen, J. Krueger, E. Guttman‐Yassky, 2017 .

Novel Insight into the Agonistic Mechanism of Alefacept In Vivo: Differentially Expressed Genes May Serve as Biomarkers of Response in Psoriasis Patients

J. Krueger, Francesca Chamian, M. Lowes, 2007 .

Psoriatic skin molecular and histopathologic profiles after treatment with risankizumab versus ustekinumab.

R. Schmid, K. Grebe, S. Visvanathan, 2019, The Journal of allergy and clinical immunology.

Risankizumab versus Ustekinumab for Moderate‐to‐Severe Plaque Psoriasis

A. Menter, M. Gooderham, K. Papp, 2017, The New England journal of medicine.

Temperature-sensitive membrane association of pp60src in tsNY68-infected cells correlates with increased tyrosine phosphorylation of membrane-associated proteins.

H. Hanafusa, J. Krueger, E. Garber, 1983, Virology.

Psoriasis vulgaris flare during efalizumab therapy does not preclude future use: a case series

J. Krueger, M. Lowes, R. Barnetson, 2005, BMC dermatology.

Decreased TNF-alpha synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4(+) T cells during ageing

J. Curnow, M. Salmon, J. Greenwood, 2010 .

Dermal clusters of mature dendritic cells and T cells are associated with the CCL20/CCR6 chemokine system in chronic psoriasis.

D. Byamba, J. Krueger, J. Fuentes-Duculan, 2014, The Journal of investigative dermatology.

Blood endotyping distinguishes the profile of vitiligo from that of other inflammatory and autoimmune skin diseases.

Hyun Je Kim, M. Lebwohl, H. Wen, 2019, The Journal of allergy and clinical immunology.

The Major Orphan Forms of Ichthyosis Are Characterized by Systemic T-Cell Activation and Th-17/Tc-17/Th-22/Tc-22 Polarization in Blood.

A. Paller, H. Wen, J. Krueger, 2018, The Journal of investigative dermatology.

Langerhans cells from human cutaneous squamous cell carcinoma induce strong type 1 immunity.

J. Carucci, D. Felsen, M. Suárez-Fariñas, 2012, The Journal of investigative dermatology.

Interleukin‐17RA blockade by brodalumab decreases inflammatory pathways in hidradenitis suppurativa skin and serum

J. Krueger, Hong Hur, S. Garcet, 2022, The British journal of dermatology.

The atopic dermatitis blood signature is characterized by increases in inflammatory and cardiovascular risk proteins

A. Dattola, M. Suárez-Fariñas, H. Wen, 2017, Scientific Reports.

New therapies for psoriasis and psoriatic arthritis

C. Ritchlin, J. Krueger, 2016, Current opinion in rheumatology.

Evolution of pathologic T-cell subsets in atopic dermatitis from infancy to adulthood.

Hyun Je Kim, A. Paller, J. Krueger, 2019, The Journal of allergy and clinical immunology.

Severe atopic dermatitis is characterized by selective expansion of circulating TH2/TC2 and TH22/TC22, but not TH17/TC17, cells within the skin-homing T-cell population.

M. Suárez-Fariñas, J. Krueger, P. Gilleaudeau, 2015, The Journal of allergy and clinical immunology.

Enhancement of cutaneous immunity during ageing by blocking p38 MAPkinase induced inflammation

Carolin T. Turner, A. Larbi, M. Noursadeghi, 2017 .

Defining drug‐free remission of skin disease in patients with plaque psoriasis

A. Menter, K. Gordon, A. Armstrong, 2019, The British journal of dermatology.

Hiding under the skin: A welcome surprise in psoriasis

J. Krueger, 2012, Nature Medicine.

Anti-IL-17 receptor antibody AMG 827 leads to rapid clinical response in subjects with moderate to severe psoriasis: results from a phase I, randomized, placebo-controlled trial.

D. Salinger, K. Papp, R. Sinclair, 2012, The Journal of investigative dermatology.

Comparative Genomic Profiling of Synovium Versus Skin Lesions in Psoriatic Arthritis

M. Suárez-Fariñas, H. Mitsui, J. Krueger, 2015, Arthritis & rheumatology.

Modulation of epidermal differentiation, tissue inflammation, and T‐lymphocyte infiltration in psoriatic plaques by topical calcitriol

A. Gottlieb, J. Krueger, P. Gilleaudeau, 1996, Journal of cutaneous pathology.

Synergistic effects of epidermal growth factor (EGF) and insulin-like growth factor I/somatomedin C (IGF-I) on keratinocyte proliferation may be mediated by IGF-I transmodulation of the EGF receptor.

D. P. Murphy, J. Krane, J. Krueger, 1991, The Journal of investigative dermatology.

Only membrane-associated RSV src proteins have amino-terminally bound lipid

H. Hanafusa, J. Krueger, E. Garber, 1983, Nature.

Approaches to reporting long-term data

K. Wittkowski, K. Papp, J. Krueger, 2010 .

Short-contact anthralin treatment augments therapeutic efficacy of cyclosporine in psoriasis: a clinical and pathologic study.

A. Gottlieb, J. Krueger, P. Gilleaudeau, 1995, Journal of the American Academy of Dermatology.

Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions.

A. Dorner, J. Krueger, P. Gilleaudeau, 1999, The Journal of clinical investigation.

The imbalance between Type 17 T-cells and regulatory immune cell subsets in psoriasis vulgaris

J. Krueger, Jaehwan Kim, A. Moreno, 2022, Frontiers in Immunology.

Comparison of the Inflammatory Circuits in Psoriasis Vulgaris, Non-Pustular Palmoplantar Psoriasis, and Palmoplantar Pustular Psoriasis.

R. Bissonnette, M. Sleeman, J. Krueger, 2022, The Journal of investigative dermatology.

Interleukin‐17 alters the biology of many cell types involved in the genesis of psoriasis, systemic inflammation and associated comorbidities

J. Krueger, P. Brunner, 2018, Experimental dermatology.

Alterations in B‐cell subsets in pediatric patients with early atopic dermatitis

A. Paller, H. Sampson, M. Suárez-Fariñas, 2017, The Journal of allergy and clinical immunology.

Tofacitinib attenuates pathologic immune pathways in patients with psoriasis: A randomized phase 2 study.

J. D. Clark, H. Valdez, M. Suárez-Fariñas, 2016, The Journal of allergy and clinical immunology.

Gene profiling of narrow-band UVB-induced skin injury defines cellular and molecular innate immune responses

M. Suárez-Fariñas, J. Krueger, M. Lowes, 2013 .

Cutaneous Expression of A Disintegrin-like and Metalloprotease domain containing Thrombospondin Type 1 motif-like 5 (ADAMTSL5) in Psoriasis goes beyond Melanocytes

J. Krueger, J. Fuentes-Duculan, Kathleen M. Bonifacio, 2016, Journal of pigmentary disorders.

MAGEA3 Expression in Cutaneous Squamous Cell Carcinoma Is Associated with Advanced Tumor Stage and Poor Prognosis.

J. Carucci, S. Meehan, A. Pavlick, 2017, The Journal of investigative dermatology.

Atopic dermatitis results in intrinsic barrier and immune abnormalities: implications for contact dermatitis.

J. Krueger, E. Guttman‐Yassky, J. Gittler, 2013, The Journal of allergy and clinical immunology.

Cyclosporine A immunosuppression drives catastrophic squamous cell carcinoma through IL-22.

J. Carucci, T. Oberyszyn, D. Felsen, 2016, JCI insight.

reportDiffering effect of systemic anti psoriasis therapies on platelet physiology-a case report and review of literature

J. Krueger, P. Gilleaudeau, M. Sullivan-Whalen, 2015 .

Differing effect of systemic anti psoriasis therapies on platelet physiology - a case report and review of literature

J. Krueger, P. Gilleaudeau, M. Sullivan-Whalen, 2010, BMC dermatology.

Skin resident memory CD8+ T cells are phenotypically and functionally distinct from circulating populations and lack immediate cytotoxic function

F. Nestle, S. Henson, A. Akbar, 2018, Clinical and experimental immunology.

Molecular profiling of contact dermatitis skin identifies allergen-dependent differences in immune response.

M. Suárez-Fariñas, M. Rozenblit, J. Krueger, 2014, The Journal of allergy and clinical immunology.

Reduction of Inflammatory and Cardiovascular Proteins in the Blood of Patients with Psoriasis: Differential Responses between Tofacitinib and Etanercept after 4 Weeks of Treatment.

H. Valdez, M. Suárez-Fariñas, L. Fitz, 2017, Journal of Investigative Dermatology.

The Spectrum of Mild to Severe Psoriasis Vulgaris Is Defined by a Common Activation of IL-17 Pathway Genes, but with Key Differences in Immune Regulatory Genes.

M. Suárez-Fariñas, R. Bissonnette, J. Krueger, 2016, The Journal of investigative dermatology.

Generalized pustular psoriasis is a disease distinct from psoriasis vulgaris: evidence and expert opinion

A. Burden, J. Barker, J. Krueger, 2022, Expert review of clinical immunology.

Patients with atopic dermatitis have attenuated and distinct contact hypersensitivity responses to common allergens in skin.

M. Suárez-Fariñas, M. Rozenblit, J. Krueger, 2015, The Journal of allergy and clinical immunology.

The treatment of moderate to severe psoriasis with a new anti-CD11a monoclonal antibody.

H. Lui, J. Shapiro, W. Gulliver, 2001, Journal of the American Academy of Dermatology.

Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis

James G. Krueger, Alice B. Gottlieb, A. Gottlieb, 1995, Nature Genetics.

Psoriasis as a model for T-cell-mediated disease: immunobiologic and clinical effects of treatment with multiple doses of efalizumab, an anti-CD11a antibody.

A. Gottlieb, K. Wittkowski, P. Walicke, 2002, Archives of dermatology.

Anti-CD4 monoclonal antibody treatment of moderate to severe psoriasis vulgaris: results of a pilot, multicenter, multiple-dose, placebo-controlled study.

A. Gottlieb, M. Lebwohl, G. Singer, 2000, Journal of the American Academy of Dermatology.

PUVA‐induced lymphocyte apoptosis: Mechanism of action in psoriasis

J. Krueger, I. Cardinale, T. Coven, 1999, Photodermatology, photoimmunology & photomedicine.

CTLA 4 Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris

M. Lebwohl, P. Linsley, H. Ochs, 1999 .

Studies of the effect of cyclosporine in psoriasis in vivo: combined effects on activated T lymphocytes and epidermal regenerative maturation.

A. Gottlieb, P. Sehgal, J. Krueger, 1992, The Journal of investigative dermatology.

Cyclosporine in psoriasis treatment. Inhibition of keratinocyte cell-cycle progression in G1 independent of effects on transforming growth factor alpha/epidermal growth factor receptor pathways.

A. Gottlieb, A. Luster, J. Krane, 1991, Archives of dermatology.

Increased dermal expression of platelet-derived growth factor receptors in growth-activated skin wounds and psoriasis.

D. P. Murphy, A. Gottlieb, J. Krane, 1990, The Journal of investigative dermatology.

Optical fiber spectroscopy measures perfusion of the brain in a murine Alzheimer's disease model

Daniel S. Gareau, Hyung Jin Ahn, Sidney Strickland, 2014, Photonics West - Biomedical Optics.

Meta-Analysis Derived (MAD) Transcriptome of Psoriasis Defines the “Core” Pathogenesis of Disease

Suyan Tian, Mayte Suárez-Fariñas, James G. Krueger, 2012, PloS one.

TH2 cytokines and Staphylococcus aureus cooperatively induce atopic dermatitis‐like transcriptomes

Shunsuke Miura, J. Krueger, Hong Hur, 2021, Allergy.

Safety, tolerability, efficacy, pharmacokinetics, and pharmacodynamics of the oral TYK2 inhibitor PF-06826647 in participants with plaque psoriasis: a phase 1, randomised, double-blind, placebo-controlled, parallel-group study

E. Peeva, J. Krueger, S. Garcet, 2021 .

Optical properties of cells with melanin

Dan Gareau, James G. Krueger, Barukh Rohde, 2014, Photonics West - Biomedical Optics.

Tumor-associated macrophages in the cutaneous SCC microenvironment are heterogeneously activated.

Mayte Suárez-Fariñas, James G. Krueger, John A. Carucci, 2011, The Journal of investigative dermatology.

Expression of Programmed Cell Death Ligand in Cutaneous Squamous Cell Carcinoma and Treatment of Locally Advanced Disease With Pembrolizumab

J. Carucci, A. Pavlick, D. Felsen, 2017, JAMA dermatology.

TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL

Rei Watanabe, James G. Krueger, Ilan R. Kirsch, 2015, Science Translational Medicine.

Evaluation of the Psoriasis Transcriptome across Different Studies by Gene Set Enrichment Analysis (GSEA)

Mayte Suárez-Fariñas, James G. Krueger, Lisa C. Zaba, 2010, PloS one.

Distinct transcriptomic profiles of early-onset atopic dermatitis in blood and skin of pediatric patients.

Hyun Je Kim, Ning Zhang, A. Paller, 2019, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Identification of TRAIL and other molecules that distinguish inflammatory DCs from resident DCs in psoriasis

N. J. Eungdamrong, Lisa C. Zaba, M. Suárez-Fariñas, 2010 .

Blockade of CD11a by efalizumab in psoriasis patients induces a unique state of T-cell hyporesponsiveness.

James G Krueger, Kathy Howell, Y. Vugmeyster, 2008, The Journal of investigative dermatology.

Novel Insight into the Agonistic Mechanism of Alefacept In Vivo: Differentially Expressed Genes May Serve as Biomarkers of Response in Psoriasis Patients1

James G Krueger, J. Krueger, Francesca Chamian, 2007, The Journal of Immunology.

Cutaneous p38 mitogen-activated protein kinase activation triggers psoriatic dermatitis.

T. Nomura, S. Ghosh, Y. Iwakura, 2019, The Journal of allergy and clinical immunology.

UV Radiation Inhibits 15-Hydroxyprostaglandin Dehydrogenase Levels in Human Skin: Evidence of Transcriptional Suppression

K. Subbaramaiah, A. Dannenberg, B. Judson, 2010, Cancer Prevention Research.

Tape-strips provide a minimally-invasive approach to track therapeutic response to topical corticosteroids in atopic dermatitis patients.

T. Agner, Ning Zhang, J. Krueger, 2020, The journal of allergy and clinical immunology. In practice.

Improving evaluation of drugs in atopic dermatitis by combining clinical and molecular measures.

J. Krueger, S. Garcet, E. Guttman‐Yassky, 2020, The journal of allergy and clinical immunology. In practice.

Comparing cutaneous molecular improvement with different treatments in atopic dermatitis patients.

J. Krueger, S. Garcet, E. Guttman‐Yassky, 2020, The Journal of allergy and clinical immunology.

Anthralin decreases keratinocyte TGF-alpha expression and EGF-receptor binding in vitro.

A. Gottlieb, J. Krane, L. Staiano‐Coico, 1992, The Journal of investigative dermatology.

Humanized anti-IFN-γ (HuZAF) in the treatment of psoriasis.

C. Leonardi, J. Krueger, M. Lowes, 2015, The Journal of allergy and clinical immunology.

The insulin-like growth factor I receptor is overexpressed in psoriatic epidermis, but is differentially regulated from the epidermal growth factor receptor

A. Gottlieb, J. Krane, J. Krueger, 1992, The Journal of experimental medicine.

IL-17 Receptor - Brodalumab, a Human Anti Psoriatic Skin by Treatment with Gene Expression Profiles Normalized in

Hugh A. Rand, D. Salinger, A. Welcher, 2014 .

Characterization of the Divergent Wound-Healing Responses Occurring in the Pathergy Reaction and Normal Healthy Volunteers1

G. Kaplan, J. Krueger, H. Yazici, 2006, The Journal of Immunology.

Characterization of the Divergent Wound-Healing Responses Occurring in the Pathergy Reaction and Normal Healthy Volunteers1

G. Kaplan, J. Krueger, H. Yazici, 2006, The Journal of Immunology.

CCL20 and IL22 Messenger RNA Expression After Adalimumab vs Methotrexate Treatment of Psoriasis: A Randomized Clinical Trial.

A. Gottlieb, M. Suárez-Fariñas, J. Krueger, 2015, JAMA dermatology.

Mild atopic dermatitis lacks systemic inflammation, and shows reduced non-lesional skin abnormalities.

Hyun Je Kim, Ning Zhang, J. Krueger, 2020, The Journal of allergy and clinical immunology.

Accelerated T-cell activation and differentiation of polar subsets characterizes early atopic dermatitis development.

A. Paller, J. Krueger, E. Guttman‐Yassky, 2016, The Journal of allergy and clinical immunology.

Reply: To PMID 25748064.

J. Krueger, E. Guttman‐Yassky, T. Czarnowicki, 2015, The Journal of allergy and clinical immunology.

Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.

Ning Zhang, H. Wen, J. Krueger, 2019, The Journal of allergy and clinical immunology.

Skin proteomic analysis of immune activation associated with regression of melanoma metastases induced by diphencyprone

J. Krueger, J. Correa da Rosa, Y. Estrada, 2022, JAAD international.

Molecular characterization of human skin response to diphencyprone at peak and resolution phases: therapeutic insights

M. Suárez-Fariñas, H. Mitsui, J. Krueger, 2014, The Journal of investigative dermatology.

Low Expression of the IL-23/Th17 Pathway in Atopic Dermatitis Compared to Psoriasis1

J. Carucci, Lisa C. Zaba, R. Bergman, 2008, The Journal of Immunology.

Cyclosporine in patients with atopic dermatitis modulates activated inflammatory pathways and reverses epidermal pathology.

M. Suárez-Fariñas, M. Rozenblit, J. Krueger, 2014, The Journal of allergy and clinical immunology.

An integrated model of alopecia areata biomarkers highlights both TH1 and TH2 upregulation.

H. Wen, G. Singer, J. Krueger, 2018, The Journal of allergy and clinical immunology.

Serum from Asian patients with atopic dermatitis is characterized by TH2/TH22 activation, which is highly correlated with nonlesional skin measures.

T. Honda, K. Kabashima, Margaret Chou, 2018, The Journal of allergy and clinical immunology.

Residual genomic profile after cyclosporine treatment may offer insights into atopic dermatitis reoccurrence.

M. Suárez-Fariñas, M. Rozenblit, J. Krueger, 2014, The Journal of allergy and clinical immunology.

Secukinumab lowers expression of ACE2 in affected skin of patients with psoriasis

A. Blauvelt, D. Murrell, J. Krueger, 2020, Journal of Allergy and Clinical Immunology.

Double-blind, placebo-controlled, dose-escalation study to evaluate the pharmacologic effect of CP-690,550 in patients with psoriasis.

G. Chan, J. Krueger, P. Changelian, 2009, The Journal of investigative dermatology.

Ustekinumab reduces serum protein levels associated with cardiovascular risk in psoriasis vulgaris

J. Krueger, S. Garcet, K. Navrazhina, 2022, Experimental dermatology.

Early quantification of systemic inflammatory-proteins predicts long-term treatment response to Tofacitinib and Etanercept: Psoriasis response predictions using blood.

H. Valdez, M. Suárez-Fariñas, L. Fitz, 2019, The Journal of investigative dermatology.

IL-32 induces indoleamine 2,3-dioxygenase+CD1c+ dendritic cells and indoleamine 2,3-dioxygenase+CD163+ macrophages: Relevance to mycosis fungoides progression

W. Sterry, J. Krueger, M. Möbs, 2017, Oncoimmunology.

Increased expression of IL‐17A and limited involvement of IL‐23 in patients with palmo‐plantar (PP) pustular psoriasis or PP pustulosis; results from a randomised controlled trial

R. Bissonnette, C. Lynde, R. Langley, 2014, Journal of the European Academy of Dermatology and Venereology : JEADV.

Attenuated neutrophil axis in atopic dermatitis compared to psoriasis reflects TH17 pathway differences between these diseases.

V. Fischetti, M. Suárez-Fariñas, J. Krueger, 2013, The Journal of allergy and clinical immunology.

The blood proteomic signature of early-onset pediatric atopic dermatitis shows systemic inflammation and is distinct from adult long-standing disease.

A. Paller, J. Krueger, P. Brunner, 2019, Journal of the American Academy of Dermatology.

Modulation of inflammatory gene transcripts in psoriasis vulgaris: Differences between ustekinumab and etanercept.

Katherine Li, M. Suárez-Fariñas, J. Krueger, 2019, The Journal of allergy and clinical immunology.

Atopic dermatitis in Chinese patients shows TH2/TH17 skewing with psoriasiform features.

H. Wen, J. Krueger, Yung-Tsu Cho, 2018, The Journal of allergy and clinical immunology.

Detection of the interferon-gamma-induced protein 10 in psoriasiform dermatitis of acquired immunodeficiency syndrome.

A. Gottlieb, B. Smoller, N. S. Mcnutt, 1990, Archives of dermatology.

A membrane protein preferentially expressed by a subpopulation of immature lymphoid cells, epidermal basal keratinocytes, and other epithelial cells.

A. Gottlieb, H. Kunkel, F. Bonetti, 1985, Journal of the American Academy of Dermatology.

Hidradenitis Suppurativa (HS) and other disorders of ‘follicular occlusion’

J. Krueger, K. Navrazhina, J. Frew, 2020 .

IL-17C: A Unique Epithelial Cytokine with Potential for Targeting across the Spectrum of Atopic Dermatitis and Psoriasis.

J. Krueger, E. Guttman‐Yassky, E. Guttman-Yassky, 2018, The Journal of investigative dermatology.

First evidence of efficacy of an orally active RORγt inhibitor in the treatment of patients with moderate to severe plaque psoriasis

S. Palmer, R. Gregg, G. Tarrasón, 2016 .

IL-36 and IL-17A Cooperatively Induce a Psoriasis-like Gene Expression Response in Human Keratinocytes.

J. Krueger, S. Garcet, Xuan Li, 2021, The Journal of investigative dermatology.

Epithelialized Tunnels are a Source of Inflammation in Hidradenitis Suppurativa.

J. Krueger, S. Garcet, P. Gilleaudeau, 2021, The Journal of allergy and clinical immunology.

Malignancy and infection risk during adalimumab therapy in hidradenitis suppurativa

R. Vaughan, J. Krueger, K. Navrazhina, 2020, Clinical and experimental dermatology.

Palmoplantar pustular psoriasis (PPPP) is characterized by activation of the IL-17A pathway.

M. Suárez-Fariñas, R. Bissonnette, J. Krueger, 2017, Journal of dermatological science.

Dermal tunnels influence time to clinical response and family history influences time to loss of clinical response in patients with hidradenitis suppurativa treated with adalimumab

R. Vaughan, J. Krueger, K. Navrazhina, 2020, Clinical and experimental dermatology.

Interleukin 17C is elevated in lesional tissue of hidradenitis suppurativa

J. Krueger, K. Navrazhina, J. Frew, 2020, The British journal of dermatology.

Clinical Response Rates, Placebo Response Rates and Significantly Associated Covariates Are Dependent Upon Choice of Outcome Measure in Hidradenitis Suppurativa: A Post-Hoc Analysis of PIONEER 1 and 2 Individual Patient Data.

Caroline S. Jiang, R. Vaughan, J. Krueger, 2019, Journal of the American Academy of Dermatology.

Definite regression of cutaneous melanoma metastases upon addition of topical contact sensitizer diphencyprone to immune checkpoint inhibitor treatment

J. Wolchok, M. Postow, R. Carvajal, 2016, Experimental dermatology.

Biomarkers of alopecia areata disease activity and response to corticosteroid treatment

M. Suárez-Fariñas, J. Krueger, Nicholas Gulati, 2016, Experimental dermatology.

Response to Hjuler et al.

J. Tardif, M. Guertin, R. Bissonnette, 2017, The Journal of investigative dermatology.

University Decreased TNF-alpha synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4(+) T cells during aging

M. Salmon, Chris D. Buckley, N. Klein, 2009 .

IL-17 induces inflammation-associated gene products in blood monocytes, and treatment with ixekizumab reduces their expression in psoriasis patient blood.

D. Shrom, M. Suárez-Fariñas, E. Dow, 2014, The Journal of investigative dermatology.

Patch testing of food allergens promotes Th17 and Th2 responses with increased IL‐33: a pilot study

H. Sampson, A. Nowak‐Wegrzyn, M. Suárez-Fariñas, 2017, Experimental dermatology.

Size-variant pp60src proteins of recovered avian sarcoma viruses interact with adhesion plaques as peripheral membrane proteins: effects on cell transformation

H. Hanafusa, J. Krueger, E. Garber, 1984, Molecular and cellular biology.

Changes in amino-terminal sequences of pp60src lead to decreased membrane association and decreased in vivo tumorigenicity

H. Hanafusa, J. Krueger, E. Garber, 1982, Cell.

Differences in intracellular location of pp60src in rat and chicken cells transformed by Rous sarcoma virus.

J. Krueger, E. Garber, A. R. Goldberg, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Evidence that the src gene product of Rous sarcoma virus is membrane associated.

J. Krueger, A. R. Goldberg, E. Wang, 1980, Virology.

A randomized, double-blind, placebo-controlled phase 1 study of multiple ascending doses of subcutaneous M1095, an anti-interleukin 17A/F nanobody, in moderate-to-severe psoriasis.

J. Krueger, R. Grenningloh, F. Casset-Semanaz, 2019, Journal of the American Academy of Dermatology.

Methotrexate improves pro- and anti-atherogenic genomic expression in psoriatic skin.

A. Gottlieb, M. Suárez-Fariñas, J. Krueger, 2016, Journal of dermatological science.

In vivo expression of the insulin‐like growth factor‐I (IGF‐I) receptor in congenital pigmented nevi

A. Gottlieb, J. Krueger, S. Colen, 1996, Journal of cutaneous pathology.

PUVA Bath Therapy Strongly Suppresses Immunological and Epide.iial Activation in Psoriasis: A Possible Cellular Basis for Remittive Therapy By Val Pierre Vallat, Patricia Gilleaudeau, Lisa Battat,

A. Gottlieb, J. Krueger, E. Hodak, 1994 .

Novel localization of pp60src in Rous sarcoma virus-transformed rat and goat cells and in chicken cells transformed by viruses rescued from these mammalian cells.

J. Krueger, E. Garber, A. R. Goldberg, 1982, Virology.

Localization and characterization of the src-gene product of Rous sarcoma virus.

J. Krueger, A. R. Goldberg, E. Wang, 1980, Cold Spring Harbor symposia on quantitative biology.

Keloid lesions show increased IL‐4/IL‐13 signaling and respond to Th2‐targeting dupilumab therapy

J. Krueger, I. Cueto, E. Guttman‐Yassky, 2019, Journal of the European Academy of Dermatology and Venereology : JEADV.

Analysis of alopecia areata surveys suggests a threshold for improved patient‐reported outcomes

G. Singer, J. Krueger, S. Garcet, 2022, The British journal of dermatology.

Efficacy, tolerability, and pharmacodynamics of apremilast in recalcitrant plaque psoriasis: a phase II open-label study.

A. Gottlieb, A. Menter, C. Leonardi, 2013, Journal of drugs in dermatology : JDD.

In-Depth Analysis of the Hidradenitis Suppurativa Serum Proteome Identifies Distinct Inflammatory Subtypes.

J. Krueger, S. Garcet, K. Navrazhina, 2021, The Journal of investigative dermatology.

15340 Long-term treatment with secukinumab led to sustained clinical improvement and normalization of inflammatory markers in patients with psoriasis

A. Armstrong, F. Kianifard, A. Blauvelt, 2020 .

Identification of a novel keratinocyte mitogen derived from bovine pituitary glands

J. Krueger, U. Gonzalez‐Castro, A. Castells-Rodellas, 1997, Archives of Dermatological Research.

An open-label, single-arm pilot study in patients with severe plaque-type psoriasis treated with an oral anti-inflammatory agent, apremilast*

B. Strober, A. Gottlieb, J. Zeldis, 2008 .

E-cadherin distribution in interleukin 6-induced cell-cell separation of ductal breast carcinoma cells.

J. Krueger, I. Cardinale, I. Tamm, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Role of T Cell Activation in the Pathogenesis of Psoriasis a

A. Gottlieb, J. Krane, J. Krueger, 1991, Annals of the New York Academy of Sciences.

Response to ‘Lack of efficacy of dupilumab in the treatment of keloid disorder’ by MH Tirgan and J Uitto

J. Krueger, I. Cueto, E. Guttman‐Yassky, 2021, Journal of the European Academy of Dermatology and Venereology : JEADV.

Assessing the responsiveness of sonographic biomarkers to Brodalumab therapy in Hidradenitis Suppurativa

J. Krueger, S. Garcet, K. Navrazhina, 2021, Journal of the European Academy of Dermatology and Venereology : JEADV.

IL32 Is Progressively Expressed in Mycosis Fungoides Independent of Helper T-cell 2 and Helper T-cell 9 Polarization

W. Sterry, M. Suárez-Fariñas, H. Mitsui, 2014, Cancer Immunology Research.

SARS‐CoV‐2 receptor ACE2 protein expression in serum is significantly associated with age

A. Paller, Rachel L. Miller, J. Krueger, 2020, Allergy.

Author Correction: The atopic dermatitis blood signature is characterized by increases in inflammatory and cardiovascular risk proteins

A. Dattola, M. Suárez-Fariñas, H. Wen, 2018, Scientific Reports.

New therapies for psoriasis and psoriatic arthritis

C. Ritchlin, J. Krueger, 2016, Current opinion in rheumatology.

Unphosphorylated gelsolin is localized in regions of cell-substratum contact or attachment in Rous sarcoma virus-transformed rat cells

L. Caliguiri, J. Krueger, I. Tamm, 1984, The Journal of cell biology.

Detection of cytokine-induced protein γ-immune protein-10 (γ-IP10) in atypical melanocytic proliferations

B. Smoller, J. Krueger, 1991 .

Clinically resolved psoriatic lesions contain psoriasis-specific IL-17–producing &agr;&bgr; T cell clones

R. Clark, H. Robins, I. Kirsch, 2017, The Journal of clinical investigation.

A Novel Chimeric Lysin Shows Superiority to Mupirocin for Skin Decolonization of Methicillin-Resistant and -Sensitive Staphylococcus aureus Strains

Chad W. Euler, V. Fischetti, J. Krueger, 2010, Antimicrobial Agents and Chemotherapy.

Proportion of CD4+CD49b+LAG-3+ Type 1 Regulatory T Cells in the Blood of Psoriasis Patients Inversely Correlates with Psoriasis Area and Severity Index.

J. Krueger, S. Garcet, J. Fuentes-Duculan, 2018, The Journal of investigative dermatology.

Immunosuppression causes dynamic changes in expression QTLs in psoriatic skin

K. Ishigaki, Y. Baglaenko, Joseph R. Mears, 2022, medRxiv.

Thalidomide induces granuloma differentiation in sarcoid skin lesions associated with disease improvement.

G. Kaplan, J. Krueger, T. Kikuchi, 2002, Clinical immunology.

Gene Expression Profiling Associated with the Progression of Classic Kaposi's Sarcoma

R. Bergman, N. Amariglio, G. Rechavi, 2012 .

An Integrated Model of Atopic Dermatitis Biomarkers Highlights the Systemic Nature of the Disease.

M. Suárez-Fariñas, J. Krueger, B. Ungar, 2017, The Journal of investigative dermatology.

Secukinumab improves mild-to-moderate psoriasis: a randomized, placebo-controlled exploratory clinical trial.

J. Krueger, Hong Hur, S. Garcet, 2022, Journal of the American Academy of Dermatology.

The rationale for Janus kinase inhibitors for the treatment of spondyloarthritis

J. Telliez, I. McInnes, D. Veale, 2018, Rheumatology.

Beyond antibodies: B cells in Hidradenitis Suppurativa: Bystanders, contributors or therapeutic targets?

J. Krueger, K. Navrazhina, J. Frew, 2020, Experimental dermatology.

Treatment Options and Goals for Patients with Generalized Pustular Psoriasis

J. Krueger, L. Puig, D. Thaçi, 2022, American Journal of Clinical Dermatology.

Microdialysis Can Detect Age-Related Differences in Glucose Distribution within the Dermis and Subcutaneous Adipose Tissue

M. Boschmann, J. Krueger, F. Murphy, 2001, Dermatology.

GM-CSF activates regenerative epidermal growth and stimulates keratinocyte proliferation in human skin in vivo.

A. Gottlieb, G. Kaplan, J. Krueger, 1994, The Journal of investigative dermatology.

Pustular psoriasis: molecular pathways and effects of spesolimab in generalized pustular psoriasis.

R. Schmid, S. Visvanathan, Patrick Baum, 2021, The Journal of allergy and clinical immunology.

Tigliane-type phorbols stimulate human melanocyte proliferation: potentially safer agents for melanocyte culture.

J. Krueger, I. Leong, A. Celá, 1990, The Journal of investigative dermatology.

Fixed drug eruptions: evidence for a cytokine‐mediated process

A. Gottlieb, B. Smoller, N. S. Mcnutt, 1991, Journal of cutaneous pathology.

058 Variable TH2/TH17-skewing places Chinese atopic dermatitis and psoriasis on an inflammatory spectrum

J. Krueger, Yung-Tsu Cho, T. C. Chan, 2018 .

434 Baseline IL-22 expression in atopic dermatitis patients stratifies therapeutic responses to fezakinumab

M. Lebwohl, J. Krueger, S. Garcet, 2018 .

313 A pathogenic role for Th22/IL-22 in atopic dermatitis is established by a placebo-controlled trial with an anti IL-22/ILV-094 mAb

M. Lebwohl, A. Neumann, M. Suárez-Fariñas, 2017 .

The therapy of psoriasis based on innate and adaptive immune mechanisms of disease pathogenesis

J. Krueger, W. Lew, F. Wang, 2004 .

Treatment of inflammatory dermatoses with novel biologic agents: a primer.

J. Krueger, R. Nussbaum, 2002, Advances in dermatology.

Junctional epidermolysis bullosa keratinocytes in culture display adhesive, structural, and functional abnormalities.

J. Krueger, A. Lin, D. Carter, 1991, The Journal of investigative dermatology.

Inactivation of c-Yes tyrosine kinase by elevation of intracellular calcium levels

H. Hanafusa, M. Sudol, Y. Zhao, 1993, Molecular and cellular biology.

An autoimmune “attack” on melanocytes triggers psoriasis and cellular hyperplasia

J. Krueger, 2015, The Journal of experimental medicine.

IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis.

P. Haslett, G. Cameron, Subhashish Banerjee, 2012, The Journal of allergy and clinical immunology.

Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells.

N. J. Eungdamrong, Lisa C. Zaba, J. Krueger, 2009, The Journal of investigative dermatology.

Common clonal origin of central and resident memory T cells following skin immunization

R. Emerson, C. Desmarais, R. Clark, 2015, Nature Medicine.

Oral JAK/SYK-inhibition (ASN002) suppresses inflammation and improves epidermal barrier markers in atopic dermatitis.

L. Denis, Ning Zhang, R. Bissonnette, 2019, The Journal of allergy and clinical immunology.

Differential expression of p62c-yes in normal, hyperplastic and neoplastic human epidermis.

M. Sudol, D. Murphy, Y. Zhao, 1991, Oncogene.

Cathelicidin Antimicrobial Peptide LL37 Induces Toll-Like Receptor 8 and Amplifies IL-36γ and IL-17C in Human Keratinocytes.

J. Krueger, S. Garcet, Xuan Li, 2022, The Journal of investigative dermatology.

Immunology of psoriasis.

Mayte Suárez-Fariñas, James G Krueger, M. Suárez-Fariñas, 2014, Annual review of immunology.

Expression and function of interleukin‐6 in epithelial cells

A. Ray, P. Sehgal, J. Krueger, 1991, Journal of cellular biochemistry.

Transcriptional profiling of psoriasis using RNA-seq reveals previously unidentified differentially expressed genes

Scott B. Dewell, M. Suárez-Fariñas, J. Krueger, 2011, The Journal of investigative dermatology.

Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis.

J. Carucci, R. Bergman, J. Krueger, 2007, The Journal of allergy and clinical immunology.

Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes.

D. P. Murphy, A. Gottlieb, T. Kupper, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Increased Expression of Interleukin 23 p19 and p40 in Lesional Skin of Patients with Psoriasis Vulgaris

M. Dhodapkar, J. Krueger, Francesca Chamian, 2004, The Journal of experimental medicine.

Increased tyrosine kinase activity of c-Src during calcium-induced keratinocyte differentiation.

H. Hanafusa, M. Sudol, Y. Zhao, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The erythema Q‐score, an imaging biomarker for redness in skin inflammation

M. Suárez-Fariñas, D. Gareau, J. Krueger, 2020, Experimental dermatology.

TNF-α downregulates filaggrin and loricrin through c-Jun N-terminal kinase: role for TNF-α antagonists to improve skin barrier.

M. Boguniewicz, D. Leung, J. Krueger, 2011, The Journal of investigative dermatology.

Interleukin 6 decreases cell-cell association and increases motility of ductal breast carcinoma cells

P. Sehgal, J. Krueger, I. Cardinale, 1989, The Journal of experimental medicine.

Skin barrier and immune dysregulation in atopic dermatitis: an evolving story with important clinical implications.

J. Krueger, E. Guttman‐Yassky, T. Czarnowicki, 2014, The journal of allergy and clinical immunology. In practice.

Petrolatum: Barrier repair and antimicrobial responses underlying this "inert" moisturizer.

M. Suárez-Fariñas, J. Krueger, P. Gilleaudeau, 2016, The Journal of allergy and clinical immunology.

Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis.

J. Ortonne, A. Menter, K. Papp, 2012, The New England journal of medicine.

A subpopulation of CD163-positive macrophages is classically activated in psoriasis.

Lisa C. Zaba, M. Suárez-Fariñas, H. Mitsui, 2010, The Journal of investigative dermatology.

Contrasting pathogenesis of atopic dermatitis and psoriasis--part II: immune cell subsets and therapeutic concepts.

J. Krueger, E. Guttman‐Yassky, K. Nograles, 2011, The Journal of allergy and clinical immunology.

Inter‐rater reliability of phenotypes and exploratory genotype–phenotype analysis in inherited hidradenitis suppurativa

J. Krueger, P. Gilleaudeau, M. Sullivan-Whalen, 2019, The British journal of dermatology.

A novel use of the cryptococcal latex agglutination test for rapid presumptive diagnosis of cutaneous cryptococcosis.

J. Krueger, D. Y. Porges, 1992, Archives of dermatology.

Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions.

Luis Puig, Giampiero Girolomoni, Paul Emery, 2010, The Journal of investigative dermatology.

Diphtheria toxin fusion proteins.

F. Foss, J. Murphy, J. Krueger, 1998, Current topics in microbiology and immunology.

Suberythemogenic narrow-band UVB is markedly more effective than conventional UVB in treatment of psoriasis vulgaris.

J. Krueger, P. Gilleaudeau, T. Coven, 1999, Journal of the American Academy of Dermatology.

Narrowband UV-B produces superior clinical and histopathological resolution of moderate-to-severe psoriasis in patients compared with broadband UV-B.

J. Krueger, P. Gilleaudeau, T. Coven, 1997, Archives of dermatology.

Potential Role of the Chemokine Receptors CXCR3, CCR4, and the Integrin αEβ7 in the Pathogenesis of Psoriasis Vulgaris

James G Krueger, J. Krueger, James B Rottman, 2001, Laboratory Investigation.

Role of IL-23 in the pathogenesis of psoriasis: a novel potential therapeutic target?

M. Chimenti, J. Krueger, R. Saraceno, 2014, Expert opinion on therapeutic targets.

Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a).

R. Steinman, K. Wittkowski, J. Krueger, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Based on Molecular Profiling of Gene Expression, Palmoplantar Pustulosis and Palmoplantar Pustular Psoriasis Are Highly Related Diseases that Appear to Be Distinct from Psoriasis Vulgaris

M. Suárez-Fariñas, R. Bissonnette, J. Krueger, 2016, PloS one.

An IL‐17–dominant immune profile is shared across the major orphan forms of ichthyosis

A. Paller, K. Choate, M. Suárez-Fariñas, 2017, The Journal of allergy and clinical immunology.

Deep learning automated pathology in ex vivo microscopy.

J. Malvehy, S. Puig, J. Carucci, 2021, Biomedical optics express.

Response to Inhibition of Receptor‐Interacting Protein Kinase 1 (RIPK1) in Active Plaque Psoriasis: A Randomized Placebo‐Controlled Study

J. Bertin, K. Papp, D. Tompson, 2020, Clinical pharmacology and therapeutics.

Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages.

R. Steinman, Lisa C. Zaba, J. Krueger, 2007, The Journal of clinical investigation.

cells and CD163 + FXIIIA + macrophages

R. Steinman, Lisa C. Zaba, J. Krueger, 2007 .

Th17 cytokines interleukin (IL)‐17 and IL‐22 modulate distinct inflammatory and keratinocyte‐response pathways

Lisa C. Zaba, M. Suárez-Fariñas, J. Krueger, 2008, The British journal of dermatology.

Successful ultraviolet B treatment of psoriasis is accompanied by a reversal of keratinocyte pathology and by selective depletion of intraepidermal T cells

A. Gottlieb, L. Austin, J. Krueger, 1995, The Journal of experimental medicine.

Contribution of fibroblasts to tunnel formation and inflammation in hidradenitis suppurativa/ acne inversa

J. Krueger, K. Navrazhina, J. Frew, 2019, Experimental dermatology.

Successful in vivo blockade of CD25 (high-affinity interleukin 2 receptor) on T cells by administration of humanized anti-Tac antibody to patients with psoriasis.

A. Gottlieb, S. Light, J. Krueger, 2000, Journal of the American Academy of Dermatology.

"Activated" keratinocyte phenotype is unifying feature in conditions which predispose to squamous cell carcinoma of the skin.

B. Smoller, J. Krueger, A. Hsu, 1990, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

Doppler ultrasound‐based noninvasive biomarkers in hidradenitis suppurativa: evaluation of analytical and clinical validity

J. Krueger, K. Navrazhina, J. Frew, 2020, The British journal of dermatology.

Role of growth factors, cytokines, and their receptors in the pathogenesis of psoriasis.

A. Gottlieb, J. Krane, J. Krueger, 1990, The Journal of investigative dermatology.

A 50% reduction in the Psoriasis Area and Severity Index (PASI 50) is a clinically significant endpoint in the assessment of psoriasis.

S. Feldman, A. Menter, G. Krueger, 2004, Journal of the American Academy of Dermatology.

Efalizumab (anti-CD11a)-induced increase in peripheral blood leukocytes in psoriasis patients is preferentially mediated by altered trafficking of memory CD8+ T cells into lesional skin.

Y. Vugmeyster, S. Bodary, J. Krueger, 2004, Clinical immunology.

CD69, HLA-DR and the IL-2R identify persistently activated T cells in psoriasis vulgaris lesional skin: blood and skin comparisons by flow cytometry.

L. Austin, J. Krueger, K. Ferenczi, 2000, Journal of autoimmunity.

Current concepts in the immunopathogenesis of psoriasis.

J. Krueger, M. Lowes, W. Lew, 2004, Dermatologic clinics.

Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array.

Wing Hung Wong, Alan Menter, James G Krueger, 2003, Physiological genomics.

Th17 Cells and Activated Dendritic Cells Are Increased in Vitiligo Lesions

Dariush Moussai, J. Krueger, Nicholas Gulati, 2011, PloS one.

IL-17 and TNF synergistically modulate cytokine expression while suppressing melanogenesis: potential relevance to psoriasis

S. Orlow, M. Suárez-Fariñas, H. Mitsui, 2013, The Journal of investigative dermatology.

Discrimination of Dysplastic Nevi from Common Melanocytic Nevi by Cellular and Molecular Criteria.

M. Suárez-Fariñas, H. Mitsui, J. Krueger, 2016, The Journal of investigative dermatology.

The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization.

T. Honda, K. Kabashima, M. Suárez-Fariñas, 2015, The Journal of allergy and clinical immunology.

Personalized medicine in psoriasis: developing a genomic classifier to predict histological response to Alefacept

Mayte Suárez-Fariñas, James G Krueger, M. Suárez-Fariñas, 2010, BMC dermatology.

Identification of TNF-related apoptosis-inducing ligand and other molecules that distinguish inflammatory from resident dendritic cells in patients with psoriasis.

N. J. Eungdamrong, Lisa C. Zaba, M. Suárez-Fariñas, 2010, The Journal of allergy and clinical immunology.

IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells.

Lisa C. Zaba, R. Bergman, J. Krueger, 2009, The Journal of allergy and clinical immunology.

TGF-α and TGF-β expression during sodium-N-butyrate-induced differentiation of human keratinocytes: Evidence for subpopulation-specific up-regulation of TGF-β mRNA in suprabasal cells☆

A. Gottlieb, P. Higgins, B. Rigas, 1990 .

Clinical clearing of psoriasis by 6-thioguanine correlates with cutaneous T-cell depletion via apoptosis: evidence for selective effects on activated T lymphocytes.

R. Auerbach, J. Krueger, I. Cardinale, 1999, Archives of dermatology.

Tofacitinib, an oral Janus kinase inhibitor, for the treatment of chronic plaque psoriasis: Long-term efficacy and safety results from 2 randomized phase-III studies and 1 open-label long-term extension study.

Robert Wolk, Steven R Feldman, James G Krueger, 2016, Journal of the American Academy of Dermatology.

Putting together the psoriasis puzzle: an update on developing targeted therapies

J. Krueger, M. Lowes, L. Johnson-Huang, 2012, Disease Models & Mechanisms.

Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells.

Lisa C. Zaba, J. Krueger, I. Cardinale, 2008, The Journal of investigative dermatology.

Clinical Symptoms of Skin, Nails, and Joints Manifest Independently in Patients with Concomitant Psoriasis and Psoriatic Arthritis

A. Gottlieb, K. Wittkowski, A. Menter, 2011, PloS one.

Transcriptomic Analysis of the Major Orphan Ichthyosis Subtypes Reveals Shared Immune and Barrier Signatures.

A. Paller, Ning Zhang, J. Krueger, 2022, The Journal of investigative dermatology.

Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing.

M. Lebwohl, M. Suárez-Fariñas, J. Krueger, 2015, The Journal of allergy and clinical immunology.

A shared tissue transcriptome signature and pathways in psoriasis and ulcerative colitis

E. Peeva, C. Hyde, J. Krueger, 2022, Scientific Reports.

IL-17A inhibition by secukinumab induces early clinical, histopathological, and molecular resolution of psoriasis.

Xiaoyu Jiang, R. Hillenbrand, W. Hueber, 2019, The Journal of allergy and clinical immunology.

Highly Effective New Treatments for Psoriasis Target the IL-23/Type 17 T Cell Autoimmune Axis.

J. Krueger, Jaehwan Kim, 2017, Annual review of medicine.

Resolved psoriasis lesions retain expression of a subset of disease-related genes.

M. Suárez-Fariñas, J. Krueger, M. Lowes, 2011, The Journal of investigative dermatology.

Type I Interferon: Potential Therapeutic Target for Psoriasis?

Yihong Yao, Laura Richman, P. Kiener, 2008, PloS one.

Getting under the skin: the immunogenetics of psoriasis

A. Bowcock, J. Krueger, 2005, Nature Reviews Immunology.

NFI Transcription Factors Provide Chromatin Access to Maintain Stem Cell Identity While Preventing Unintended Lineage Fate Choices

D. Zheng, E. Fuchs, R. Gronostajski, 2020, Nature Cell Biology.

Modulation of Inflammatory Proteins in Serum May Reflect Cutaneous Immune Responses in Cancer Immunotherapy

Aatman Shah, K. Sarin, J. Krueger, 2023, JID innovations : skin science from molecules to population health.

Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis.

Hyun Je Kim, T. Tuschl, P. Morozov, 2020, The Journal of allergy and clinical immunology.

The skin as an immune organ: Tolerance versus effector responses and applications to food allergy and hypersensitivity reactions.

J. Krueger, E. Guttman‐Yassky, Lisa Zhou, 2019, The Journal of allergy and clinical immunology.

A single intradermal injection of IFN-γ induces an inflammatory state in both non-lesional psoriatic and healthy skin

M. Suárez-Fariñas, J. Krueger, M. Lowes, 2011, The Journal of investigative dermatology.

First-In-Human, Phase 1, Randomized, Dose-Escalation Trial with Recombinant Anti–IL-20 Monoclonal Antibody in Patients with Psoriasis

A. Gottlieb, B. Skolnick, J. Krueger, 2015, PloS one.

A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis

Jurg Ott, Pui-Yan Kwok, Derek Gordon, 2003, Nature Genetics.

Contrasting pathogenesis of atopic dermatitis and psoriasis--part I: clinical and pathologic concepts.

J. Krueger, E. Guttman‐Yassky, K. Nograles, 2011, The Journal of allergy and clinical immunology.

New insights in the immunologic basis of psoriasis.

J. Krueger, B. Davidovici, K. Nograles, 2010, Seminars in cutaneous medicine and surgery.

Broad defects in epidermal cornification in atopic dermatitis identified through genomic analysis.

Mayte Suárez-Fariñas, James G Krueger, Andrea Chiricozzi, 2009, The Journal of allergy and clinical immunology.

Tumor-associated macrophages in the cutaneous SCC microenvironment are heterogeneously activated.

Mayte Suárez-Fariñas, John A Carucci, James G Krueger, 2011, The Journal of investigative dermatology.

The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses.

David A. Martin, J. Krueger, M. Lowes, 2013, Trends in immunology.

Intrinsic atopic dermatitis shows similar TH2 and higher TH17 immune activation compared with extrinsic atopic dermatitis.

M. Suárez-Fariñas, J. Krueger, I. Cardinale, 2013, The Journal of allergy and clinical immunology.

Progressive activation of T(H)2/T(H)22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis.

M. Suárez-Fariñas, H. Mitsui, J. Krueger, 2012, The Journal of allergy and clinical immunology.

Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities.

A. Bowcock, S. Duan, M. Suárez-Fariñas, 2011, The Journal of allergy and clinical immunology.

Combined Use of Laser Capture Microdissection and cDNA Microarray Analysis Identifies Locally Expressed Disease-Related Genes in Focal Regions of Psoriasis Vulgaris Skin Lesions

Hideki Fujita, Mayte Suárez-Fariñas, James G. Krueger, 2012, The Journal of investigative dermatology.

Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

Lisa C. Zaba, M. Suárez-Fariñas, J. Krueger, 2007, The Journal of experimental medicine.

Cell-adhesion-disrupting action of interleukin 6 in human ductal breast carcinoma cells.

J G Krueger, J. Krueger, I. Cardinale, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Molecular classification of psoriasis disease-associated genes through pharmacogenomic expression profiling

J G Krueger, A. Dorner, J. Krueger, 2001, The Pharmacogenomics Journal.

Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia.

J. Ott, A. Bowcock, J. Carucci, 2006, The Journal of investigative dermatology.

Mechanisms Underlying the Clinical Effects of Apremilast for Psoriasis.

L. French, M. Augustin, C. Pincelli, 2018, Journal of drugs in dermatology : JDD.

An open-label, single-arm pilot study in patients with severe plaque-type psoriasis treated with an oral anti-inflammatory agent, apremilast.

B. Strober, A. Gottlieb, J. Zeldis, 2008, Current medical research and opinion.

Synergistic cytokine effects as apremilast response predictors in patients with psoriasis.

J. Krueger, P. Schafer, S. Garcet, 2018, The Journal of allergy and clinical immunology.

The immunopathogenesis of psoriasis.

J. Krueger, Jaehwan Kim, 2015, Dermatologic clinics.

Application of a unique monoclonal antibody as a marker for nonproliferating subpopulations of cells of some tissue.

J. Krueger, E. Wang, 1985, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

The proteomic skin profile of moderate-to-severe atopic dermatitis patients shows an inflammatory signature.

J. Krueger, B. Ungar, E. Guttman‐Yassky, 2020, Journal of the American Academy of Dermatology.

Expanding the Psoriasis Disease Profile: Interrogation of the Skin and Serum of Patients with Moderate-to-Severe Psoriasis

Mayte Suárez-Fariñas, James G Krueger, Katherine Li, 2012, The Journal of investigative dermatology.

Accumulating evidence for the association and shared pathogenic mechanisms between psoriasis and cardiovascular-related comorbidities.

B. Strober, A. Kimball, A. Qureshi, 2014, The American journal of medicine.

The human CIB1–EVER1–EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses

J. Casanova, E. Fuchs, J. Franco, 2018, The Journal of experimental medicine.

Enhancement of cutaneous immunity during aging by blocking p38 mitogen-activated protein (MAP) kinase–induced inflammation

Carolin T. Turner, A. Larbi, M. Noursadeghi, 2017, The Journal of allergy and clinical immunology.

HER1/EGFR inhibitor-associated rash: future directions for management and investigation outcomes from the HER1/EGFR inhibitor rash management forum.

A. Halpern, J. Leyden, J. Temel, 2005, The oncologist.

Integrative responses to IL-17 and TNF-α in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis.

S. Chimenti, S. Tian, M. Suárez-Fariñas, 2011, The Journal of investigative dermatology.

Evolution of pathologic T-cell subsets in patients with atopic dermatitis from infancy to adulthood

Hyun Je Kim, A. Paller, J. Krueger, 2019 .

Increased cardiovascular and atherosclerosis markers in blood of older atopic dermatitis patients.

J. Krueger, E. Guttman‐Yassky, A. Pavel, 2019, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Single-cell transcriptomics applied to emigrating cells from psoriasis elucidate pathogenic vs. regulatory immune cell subsets.

Hyun Je Kim, C. Putterman, J. Krueger, 2021, The Journal of allergy and clinical immunology.

Deep Sequencing of the T-cell Receptor Repertoire Demonstrates Polyclonal T-cell Infiltrates in Psoriasis

J. Krueger, M. Lowes, Nicholas Gulati, 2015, F1000Research.

Increased Tc22 and Treg/CD8 Ratio Contribute to Aggressive Growth of Transplant Associated Squamous Cell Carcinoma

J. Carucci, D. Felsen, M. Suárez-Fariñas, 2013, PloS one.

Human basal cell carcinoma is associated with Foxp3+ T cells in a Th2 dominant microenvironment.

J. Carucci, J. Krueger, I. Cardinale, 2007, The Journal of investigative dermatology.

Novel concepts of prevention and treatment of atopic dermatitis through barrier and immune manipulations with implications for the atopic march.

J. Krueger, E. Guttman‐Yassky, T. Czarnowicki, 2017, The Journal of allergy and clinical immunology.

Characterisation of the cutaneous pathology in non-small cell lung cancer (NSCLC) patients treated with the EGFR tyrosine kinase inhibitor erlotinib.

J. Verweij, M. D. de Jonge, A. Mita, 2010, European journal of cancer.

Atypical Erythema Migrans in Patients with PCR-Positive Lyme Disease

D. Ecker, J. Aucott, M. Eshoo, 2013, Emerging infectious diseases.

Identification of anaplastic lymphoma kinase as a potential therapeutic target in Basal Cell Carcinoma

J. Carucci, D. Felsen, Jie Chen, 2013, Oncotarget.

An Animal Explant Model for the Study of Human Cutaneous Squamous Cell Carcinoma

J. Carucci, D. Poppas, D. Felsen, 2013, PloS one.

Laser capture microdissection followed by next‐generation sequencing identifies disease‐related microRNAs in psoriatic skin that reflect systemic microRNA changes in psoriasis

M. Hafner, J. Zibert, L. Skov, 2015, Experimental dermatology.

Systemic immune mechanisms in atopic dermatitis and psoriasis with implications for treatment

M. Lebwohl, J. Krueger, E. Guttman‐Yassky, 2018, Experimental dermatology.

Novel immune signatures associated with dysplastic naevi and primary cutaneous melanoma in human skin

H. Mitsui, J. Krueger, F. Kiecker, 2018, Experimental dermatology.

Human keratinocyte growth factor effects in a porcine model of epidermal wound healing

A. Gottlieb, J. Rubin, S. Aaronson, 1993, The Journal of experimental medicine.

IL-17 targeted therapies for psoriasis

J. Krueger, A. Chiricozzi, 2013, Expert opinion on investigational drugs.

Human Langerhans cells induce distinct IL-22-producing CD4+ T cells lacking IL-17 production

J. Carucci, J. Krueger, H. Fujita, 2009, Proceedings of the National Academy of Sciences.

An integrated scalp and blood biomarker approach suggests the systemic nature of alopecia areata

Ning Zhang, G. Singer, J. Krueger, 2021, Allergy.

The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings.

Jennifer E Towne, James G Krueger, J. Gudjonsson, 2013, The Journal of investigative dermatology.

Psoriasis vulgaris: cutaneous lymphoid tissue supports T-cell activation and "Type 1" inflammatory gene expression.

A. Bowcock, J. Krueger, W. Lew, 2004, Trends in immunology.

Suppression of Molecular Inflammatory Pathways by Toll-Like Receptor 7, 8, and 9 Antagonists in a Model of IL-23-Induced Skin Inflammation

R. Arbeit, M. Suárez-Fariñas, J. Krueger, 2013, PloS one.

Combining several ordinal measures in clinical studies

James G Krueger, K. Wittkowski, J. Krueger, 2004, Statistics in medicine.

Interleukin 23 in the skin: role in psoriasis pathogenesis and selective interleukin 23 blockade as treatment

J. Krueger, T. C. Chan, J. Hawkes, 2018, Therapeutic advances in chronic disease.

oligonucleotide array revealed by profiling of psoriasis on the 63,100-element Novel mechanisms of T-cell and dendritic cell activation

W. Wong, A. Bowcock, X. Zhou, 2016 .

63,100-element oligonucleotide array activation revealed by profiling of psoriasis on the Novel mechanisms of T-cell and dendritic cell

X. Zhou, M. Kao, M. Chance, 2015 .

Analytical approaches to reporting long-term clinical trial data.

K. Wittkowski, K. Papp, J. Krueger, 2008, Current medical research and opinion.

Bimekizumab efficacy and safety in moderate to severe plaque psoriasis (BE READY): a multicentre, double-blind, placebo-controlled, randomised withdrawal phase 3 trial

K. Reich, P. Foley, K. Gordon, 2021, The Lancet.

Effective narrow-band UVB radiation therapy suppresses the IL-23/IL-17 axis in normalized psoriasis plaques.

M. Suárez-Fariñas, J. Krueger, M. Lowes, 2010, The Journal of investigative dermatology.

Efficacy of Tofacitinib for the Treatment of Moderate-to-Severe Chronic Plaque Psoriasis in Patient Subgroups from Two Randomised Phase 3 Trials.

J. Wohlrab, K. Papp, H. Valdez, 2016, Journal of drugs in dermatology : JDD.

Signalling of multiple interleukin (IL)‐17 family cytokines via IL‐17 receptor A drives psoriasis‐related inflammatory pathways

J. Krueger, S. Garcet, M. Bertelsen, 2021, The British journal of dermatology.

Narrowband (312-nm) UV-B suppresses interferon gamma and interleukin (IL) 12 and increases IL-4 transcripts: differential regulation of cytokines at the single-cell level.

J. Krueger, I. Cardinale, P. Gilleaudeau, 2003, Archives of dermatology.

Diverse activation and differentiation of multiple B-cell subsets in patients with atopic dermatitis but not in patients with psoriasis.

J. Krueger, J. Fuentes-Duculan, S. Noda, 2016, The Journal of allergy and clinical immunology.

Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement.

Ning Zhang, G. Singer, J. Krueger, 2021, Journal of the American Academy of Dermatology.

Tape strips detect distinct immune and barrier profiles in atopic dermatitis and psoriasis.

Ning Zhang, R. Bissonnette, J. Krueger, 2020, The Journal of allergy and clinical immunology.

Aurora Kinase A Is Upregulated in Cutaneous T-Cell Lymphoma and Represents a Potential Therapeutic Target.

Mayte Suárez-Fariñas, Michael Hummel, Jürgen Eberle, 2015, The Journal of investigative dermatology.

Characterization of PCSK9 in the Blood and Skin of Psoriasis.

T. Powell-Wiley, E. Fisher, N. Mehta, 2020, The Journal of investigative dermatology.

Early-onset pediatric atopic dermatitis is TH2 but also TH17 polarized in skin.

A. Paller, M. Suárez-Fariñas, J. Krueger, 2016, The Journal of allergy and clinical immunology.

Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes.

Mayte Suárez-Fariñas, James G Krueger, Lisa C. Zaba, 2009, The Journal of allergy and clinical immunology.

CD 200 Upregulation in Vascular Endothelium Surrounding Cutaneous Squamous Cell Carcinoma

J. Carucci, D. Felsen, M. Suárez-Fariñas, 2012 .

PUVA Treatment Selectively Induces a Cell Cycle Block and Subsequent Apoptosis in Human T‐Lymphocytes

L. Staiano‐Coico, L. Austin, J. Krueger, 1996, Photochemistry and Photobiology.

Histological Stratification of Thick and Thin Plaque Psoriasis Explores Molecular Phenotypes with Clinical Implications

Dong Joo Kim, M. Suárez-Fariñas, J. Krueger, 2015, PloS one.

Anti-IL-23A mAb BI 655066 for treatment of moderate-to-severe psoriasis: Safety, efficacy, pharmacokinetics, and biomarker results of a single-rising-dose, randomized, double-blind, placebo-controlled trial.

L. Ferris, A. White, A. Menter, 2015, The Journal of allergy and clinical immunology.

Association between biologic therapies for chronic plaque psoriasis and cardiovascular events: a meta-analysis of randomized controlled trials.

B. Strober, A. Kimball, J. D. de Lemos, 2011, JAMA.

Peripheral Blood Lymphoid Cells to Tumor Membrane Extracts Differences in the Responsiveness of Splenic, Lymph Node, and

R. Segal, J. Krueger, R. Moyer, 2013 .

Deep learning-level melanoma detection by interpretable machine learning and imaging biomarker cues

Mayte Suarez-Farinas, Josep Malvehy, James Browning, 2020, Journal of biomedical optics.

Hyperspectral imaging in automated digital dermoscopy screening for melanoma

Kristen M Kelly, Samantha Lish, Steven L Jacques, 2019, Lasers in surgery and medicine.

Hyperspectral imaging for melanoma screening

Daniel S. Gareau, James G. Krueger, Justin Martin, 2014, Photonics West - Biomedical Optics.

Early‐onset pediatric atopic dermatitis is characterized by TH2/TH17/TH22‐centered inflammation and lipid alterations

Ning Zhang, A. Paller, H. Wen, 2018, The Journal of allergy and clinical immunology.

Identification of Cellular Pathways of “Type 1,” Th17 T Cells, and TNF- and Inducible Nitric Oxide Synthase-Producing Dendritic Cells in Autoimmune Inflammation through Pharmacogenomic Study of Cyclosporine A in Psoriasis1

K. Wittkowski, Lisa C. Zaba, M. Suárez-Fariñas, 2008, The Journal of Immunology.

AJC editor's consensus: psoriasis and coronary artery disease.

P. Ridker, S. Grundy, W. Roberts, 2008, The American journal of cardiology.

Prominent production of IL-20 by CD68+/CD11c+ myeloid-derived cells in psoriasis: Gene regulation and cellular effects.

J. Krueger, Francesca Chamian, I. Cardinale, 2006, The Journal of investigative dermatology.

Eruptive papules during efalizumab (anti-CD11a) therapy of psoriasis vulgaris: a case series

K. Papp, C. Leonardi, J. Krueger, 2007, BMC dermatology.

Cutting Edge: Selective Oral ROCK2 Inhibitor Reduces Clinical Scores in Patients with Psoriasis Vulgaris and Normalizes Skin Pathology via Concurrent Regulation of IL-17 and IL-10

Wei Chen, Mark Lebwohl, James G Krueger, 2017, The Journal of Immunology.

Activated Platelets Induce Endothelial Cell Inflammatory Response in Psoriasis via COX-1

E. Fisher, A. Neimann, N. Mehta, 2020, Arteriosclerosis, thrombosis, and vascular biology.

Psoriasis is characterized by deficient negative immune regulation compared to transient delayed-type hypersensitivity reactions

M. Suárez-Fariñas, J. Krueger, Nicholas Gulati, 2015, F1000Research.

Gene Expression Profiles Normalized in Psoriatic Skin by Treatment with Brodalumab, a Human Anti–IL-17 Receptor Monoclonal Antibody

Hugh A. Rand, D. Salinger, David A. Martin, 2014, The Journal of Immunology.

Molecular and Cellular Responses to the TYK2/JAK1 Inhibitor, PF 06700841, Reveal Reduction of Skin Inflammation in Plaque Psoriasis: TYK2/JAK1 inhibitor in plaque psoriasis.

E. Peeva, M. Suárez-Fariñas, C. Banfield, 2020, The Journal of investigative dermatology.

IL-4Rα Blockade by Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Atopic Dermatitis

R. Knight, J. Silverberg, T. Kosciólek, 2019, Journal of Investigative Dermatology.

RNA sequencing atopic dermatitis transcriptome profiling provides insights into novel disease mechanisms with potential therapeutic implications.

Mayte Suárez-Fariñas, Hui Xu, James G Krueger, 2015, The Journal of allergy and clinical immunology.

Two considerations for patients with psoriasis and their clinicians: what defines mild, moderate, and severe psoriasis? What constitutes a clinically significant improvement when treating psoriasis?

James T. Elder, A. Gottlieb, M. Lebwohl, 2000, Journal of the American Academy of Dermatology.

P3-115: Erlotinib (Tarcevar) “dosing–to–rash”: characterization of skin toxicity from a pilot phase II intra–patient dose–escalation study of E in previously treated patients with advanced non–small cell lung cancer (NSCLC)

J. Verweij, K. Papadopoulos, M. Mita, 2007 .

A systematic review and critical appraisal of metagenomic and culture studies in hidradenitis suppurativa

J. Krueger, J. Frew, S. Williams, 2020, Experimental dermatology.

Large‐scale serum analysis identifies unique systemic biomarkers in psoriasis and hidradenitis suppurativa *

J. Krueger, S. Garcet, K. Navrazhina, 2021, The British journal of dermatology.

Scalp biomarkers during dupilumab treatment support Th2 pathway pathogenicity in alopecia areata

M. Lebwohl, J. Krueger, S. Garcet, 2022, Allergy.

Molecular and clinical effects of selective TYK2 inhibition with deucravacitinib in psoriasis.

K. Gordon, Subhashish Banerjee, J. Krueger, 2021, The Journal of allergy and clinical immunology.

Potential role of the chemokine receptors CXCR3, CCR4, and the integrin alphaEbeta7 in the pathogenesis of psoriasis vulgaris.

J G Krueger, J. Krueger, J B Rottman, 2001, Laboratory investigation; a journal of technical methods and pathology.

Transcriptomic Profiling of Tape-Strips From Moderate to Severe Atopic Dermatitis Patients Treated With Dupilumab

T. Agner, Ning Zhang, J. Krueger, 2021, Dermatitis : contact, atopic, occupational, drug.

The Rockefeller University Clinical Scholars (KL2) program 2006–2016

J. Tobin, Yupu Liang, B. Coller, 2017, Journal of Clinical and Translational Science.

The aging skin microenvironment dictates stem cell behavior

O. Elemento, E. Fuchs, A. Verma, 2020, Proceedings of the National Academy of Sciences.

Major differences in expression of inflammatory pathways in skin from different body sites of healthy individuals.

R. Bissonnette, J. Krueger, E. Guttman‐Yassky, 2019, The Journal of investigative dermatology.

Vascular inflammation in moderate‐to‐severe atopic dermatitis is associated with enhanced Th2 response

J. Tardif, Ning Zhang, R. Bissonnette, 2021, Allergy.

A preliminary 18F-FDG-PET/MRI study shows increased vascular inflammation in moderate-to-severe atopic dermatitis.

M. Lebwohl, Z. Fayad, P. Robson, 2020, The journal of allergy and clinical immunology. In practice.

Cross-sectional study of blood biomarkers of patients with moderate-to-severe alopecia areata reveals systemic immune and cardiovascular biomarker dysregulation.

G. Singer, J. Krueger, E. Guttman‐Yassky, 2020, Journal of the American Academy of Dermatology.

Identification of aberrantly regulated genes in diseased skin using the cDNA differential display technique.

A. Gottlieb, M. Rivas, J. Krueger, 1997, The Journal of investigative dermatology.

Delayed type hypersensitivity reactions to various allergens may differently model inflammatory skin diseases

R. Bissonnette, J. Krueger, F. Ramírez-Valle, 2022, Allergy.

Effect of Costimulatory Blockade With Abatacept After Ustekinumab Withdrawal in Patients With Moderate to Severe Plaque Psoriasis

S. Feldman, W. Barry, Y. Helfrich, 2021, JAMA dermatology.

Autoimmunity in Psoriasis: Evidence for Specific Autoantigens

J. Krueger, J. Hawkes, Jose A. Gonzalez, 2017, Current Dermatology Reports.

Insights into gene modulation by therapeutic TNF and IFNgamma antibodies: TNF regulates IFNgamma production by T cells and TNF-regulated genes linked to psoriasis transcriptome.

J. Ott, Lisa C. Zaba, J. Krueger, 2008, Journal of Investigative Dermatology.

A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue

M. Ferrer, J. Carucci, N. Doudican, 2020, Oncotarget.

Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways

C. Workman, T. Litman, S. Tian, 2015, BMC Medical Genomics.

Building an infrastructure to support the development, conduct, and reporting of informative clinical studies: The Rockefeller University experience

J. Tobin, B. Coller, J. Krueger, 2023, Journal of Clinical and Translational Science.

Trimethylpsoralen bath PUVA is a remittive treatment for psoriasis vulgaris. Evidence that epidermal immunocytes are direct therapeutic targets.

J. Krueger, I. Cardinale, P. Gilleaudeau, 1998, Archives of dermatology.

Phase 2a randomized clinical trial of dupilumab (anti‐IL‐4Rα) for alopecia areata patients

M. Lebwohl, G. Singer, J. Krueger, 2021, Allergy.

Proteomic profiling of a patient with cutaneous melanoma metastasis regression following topical contact sensitizer diphencyprone and immune checkpoint inhibitor treatment

J. Krueger, Y. Estrada, Aneesh Agarwal, 2022, Scientific Reports.

Short-term transcriptional response to IL-17 Receptor-A antagonism in the treatment of Psoriasis.

M. Suárez-Fariñas, J. Krueger, P. Klekotka, 2019, The Journal of allergy and clinical immunology.

Psoriasis and Other Skin Inflammatory Diseases

J. Krueger, Jae Hwan Kim, 2017 .

Weekly administration of brodalumab in hidradenitis suppurativa: an open‐label cohort study

J. Krueger, S. Garcet, P. Gilleaudeau, 2020, The British journal of dermatology.

The Effect of Subcutaneous Brodalumab upon Clinical Disease Activity in Hidradenitis Suppurativa: An Open Label Cohort Study.

J. Krueger, S. Garcet, P. Gilleaudeau, 2020, Journal of the American Academy of Dermatology.

Cellular actions of etretinate in psoriasis: enhanced epidermal differentiation and reduced cell‐mediated inflammation are unexpected outcomes

A. Gottlieb, J. Krueger, I. Cardinale, 1996, Journal of cutaneous pathology.

Efficacy and safety of fezakinumab (an IL‐22 monoclonal antibody) in adults with moderate‐to‐severe atopic dermatitis inadequately controlled by conventional treatments: A randomized, double‐blind, phase 2a trial

M. Lebwohl, A. Neumann, G. Singer, 2018, Journal of the American Academy of Dermatology.

Unique microRNAs appear at different times during the course of a delayed‐type hypersensitivity reaction in human skin

T. Tuschl, J. Zibert, N. Renwick, 2015, Experimental dermatology.

IL-17 Induces an Expanded Range of Downstream Genes in Reconstituted Human Epidermis Model

M. Suárez-Fariñas, H. Mitsui, J. Krueger, 2014, PloS one.

Cellular genomic maps help dissect pathology in human skin disease.

Lisa C. Zaba, M. Blumenberg, M. Suárez-Fariñas, 2008, The Journal of investigative dermatology.

Cytokine-Producing Dendritic Cells in the Pathogenesis of Inflammatory Skin Diseases

J. Krueger, M. Lowes, L. Johnson-Huang, 2009, Journal of Clinical Immunology.

Effects of administration of a single dose of a humanized monoclonal antibody to CD11a on the immunobiology and clinical activity of psoriasis.

M. Lebwohl, K. Wittkowski, H. Ochs, 2000, Journal of the American Academy of Dermatology.

Dendritic cells are contained within melanocytic nevus nests in vivo and can alter gene expression of epidermal melanocytes in vitro

M. Suárez-Fariñas, H. Mitsui, J. Krueger, 2015, Pigment Cell & Melanoma Research.

Major differences between human atopic dermatitis and murine models, as determined by using global transcriptomic profiling

Mayte Suárez-Fariñas, Christopher T Workman, Hui Xu, 2016, The Journal of allergy and clinical immunology.

Gene expression profiling of the leading edge of cutaneous squamous cell carcinoma (SCC): IL-24 driven MMP-7

J. Carucci, D. Felsen, M. Suárez-Fariñas, 2013, The Journal of investigative dermatology.

Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection.

T. Litman, M. Suárez-Fariñas, M. Rozenblit, 2015, The Journal of allergy and clinical immunology.

CCL20 in Psoriasis: A Potential Biomarker of Disease Severity, Inflammation, and Impaired Vascular Health.

E. Fisher, A. Neimann, J. Berger, 2020, Journal of the American Academy of Dermatology.

Inflammasome Signaling and Impaired Vascular Health in Psoriasis

E. Fisher, A. Neimann, J. Berger, 2019, Arteriosclerosis, thrombosis, and vascular biology.

Nonlesional atopic dermatitis skin shares similar T‐cell clones with lesional tissues

R. Emerson, J. Krueger, S. Garcet, 2017, Allergy.

The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus

C. Blobel, P. Lipsky, I. Rogatsky, 2021, bioRxiv.

The Impact of Body Mass Index Upon the Efficacy of Adalimumab in Hidradenitis Suppurativa

J. Krueger, J. Frew, R. Vaughan, 2021, Frontiers in Medicine.

NFI Transcription Factors Provide Chromatin Access to Maintain Stem Cell Identity While Preventing Unintended Lineage Fate Choices

D. Zheng, E. Fuchs, R. Gronostajski, 2020, Nature Cell Biology.

IL-23/T H 17 Pathway in Psoriasis and Inflammatory Skin Diseases

J. Krueger, B. Davidovici, K. Nograles, 2011 .

102 Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Patients With Atopic Dermatitis

R. Knight, J. Silverberg, C. Callewaert, 2019, Journal of Investigative Dermatology.

Bimekizumab versus Ustekinumab Efficacy Across Subgroups of Patients with Moderate to Severe Plaque Psoriasis: Results from the Multicenter, Randomized, Double-Blinded Phase 3 BE VIVID Trial

B. Strober, D. Toth, J. Krueger, 2021 .

Molecular Phenotyping Small (Asian) versus Large (Western) Plaque Psoriasis Shows Common Activation of IL-17 Pathway Genes, but Different Regulatory Gene Sets

Dong Joo Kim, M. Suárez-Fariñas, C. Oh, 2015, The Journal of investigative dermatology.

High‐dimensional analysis defines multicytokine T‐cell subsets and supports a role for IL‐21 in atopic dermatitis

Hyun Je Kim, M. Merad, Adeeb H. Rahman, 2021, Allergy.

Intrapatient comparison of atopic dermatitis skin transcriptome shows differences between tape‐strips and biopsies

Y. Liu, R. Bissonnette, J. Krueger, 2023, Allergy.

Cutaneous Adverse Events in the Randomized, Double-Blind, Active-Comparator DECIDE Study of Daclizumab High-Yield Process Versus Intramuscular Interferon Beta-1a in Relapsing-Remitting Multiple Sclerosis

M. Sweetser, A. Friedman, S. Greenberg, 2016, Advances in Therapy.

Shrinking the Psoriasis Assessment Gap: Early Gene-Expression Profiling Accurately Predicts Response to Long-Term Treatment.

S. Tian, M. Suárez-Fariñas, J. Krueger, 2017, The Journal of investigative dermatology.

Genomic profiling of the overlap phenotype between psoriasis and atopic dermatitis.

J. E. Kim, J. Krueger, Jongmi Lee, 2023, The Journal of investigative dermatology.

International observational atopic dermatitis cohort to follow natural history and treatment course: TARGET-DERM AD study design and rationale

J. Silverberg, A. Paller, K. Abuabara, 2020, BMJ Open.

Guselkumab More Effectively Neutralizes Psoriasis-Associated Histologic, Transcriptomic, and Clinical Measures than Ustekinumab

Katherine Li, J. Krueger, S. Garcet, 2023, ImmunoHorizons.

Persistence of inflammatory phenotype in residual psoriatic plaques in patients on effective biologic therapy: Residual Psoriatic Plaques After Treatment.

Kathleen M. Smith, V. Kaimal, R. Bissonnette, 2019, The Journal of investigative dermatology.

P504 Guselkumab, an IL-23p19 subunit–specific monoclonal antibody, binds CD64+ myeloid cells and potently neutralises IL-23 produced from the same cells

R. Atreya, D. Hammaker, I. McInnes, 2023, Journal of Crohn's and Colitis.

Enhanced membrane binding of autoantibodies to cultured keratinocytes of systemic lupus erythematosus patients after ultraviolet B/ultraviolet A irradiation.

K. Elkon, J. Krueger, A. Gharavi, 1992, The Journal of clinical investigation.

Secukinumab versus guselkumab in the complete resolution of ustekinumab‐resistant psoriatic plaques: The ARROW study

F. Kolbinger, K. Reich, R. Langley, 2023, Experimental dermatology.

Creation of differentiation-specific genomic maps of human epidermis through laser capture microdissection

M. Suárez-Fariñas, H. Mitsui, J. Krueger, 2013, The Journal of investigative dermatology.

Increased JunB mRNA and protein expression in psoriasis vulgaris lesions.

J. Krueger, A. Haider, Julia A Whynot, 2006, The Journal of investigative dermatology.

The Busy Arena of Psoriasis Treatments: Improving the Clinician’s Ability to Make the Right Therapeutic Choice

J. Tobin, J. Krueger, Y. Renert-Yuval, 2021, American Journal of Clinical Dermatology.

Hyperactivation of the JAK2/STAT5 Signaling Pathway and Evaluation of Baricitinib Treatment Among Patients With Eosinophilic Cellulitis.

Jean Kanitakis, J. Krueger, M. Vocanson, 2023, JAMA dermatology.

Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

Lisa C. Zaba, M. Suárez-Fariñas, J. Krueger, 2008, The Journal of Experimental Medicine.

Non-lesional atopic dermatitis skin shares similar T-cell clones with lesional tissues Short title : T-cell receptor repertoire in lesional and non-lesional AD

R. Emerson, J. Krueger, S. Garcet, 2017 .

Modulation of cardiometabolic pathways in skin and serum from patients with psoriasis

N. Mehta, Katherine Li, J. Krueger, 2013, Journal of Translational Medicine.

pathogenesispathophysiology: current concepts of

J G Krueger, A Bowcock, A. Bowcock, 2006 .

Fiberoptic hemodynamic spectroscopy reveals abnormal cerebrovascular reactivity in a freely moving mouse model of Alzheimer’s disease

S. Jacques, M. Snuderl, S. Strickland, 2023, Frontiers in Molecular Neuroscience.

Early intervention in psoriasis and immune-mediated inflammatory diseases: A hypothesis paper

P. Emery, F. Nestle, J. Krueger, 2015, The Journal of dermatological treatment.

A prospective phase III, randomized, double‐blind, placebo‐controlled study of brodalumab in patients with moderate‐to‐severe plaque psoriasis

A. Gottlieb, K. Papp, K. Reich, 2016, The British journal of dermatology.

Fiberoptic Hemodynamic Spectroscopy: validation in glioma model and magnetic probe to study cerebrovascular dysregulation in freely-moving Alzheimer’s disease model mice

S. Jacques, M. Snuderl, S. Strickland, 2023, bioRxiv.

Pharmacokinetics and Pharmacodynamics of Multiple Weekly Subcutaneous Efalizumab Doses in Patients With Plaque Psoriasis

A. Gottlieb, P. Kuebler, B. Miller, 2005, Journal of clinical pharmacology.

A multiple dose randomized double-blind placebo-controlled study to determine the efficacy and safety of a humanized anti-CD4 monoclonal antibody in the treatment of moderate to severe chronic psoriasis vulgaris

A. Gottlieb, M. Lebwohl, M. Wacholtz, 1998 .

Recessive dystrophic epidermolysis bullosa skin displays a chronic growth-activated immunophenotype. Implications for carcinogenesis.

A. Gottlieb, J. Krueger, D. Carter, 1990 .

Staphylococcus Aureus and Streptococcus Pyogenes Induce Psoriasis-Related Transcriptomes Augmented by IL-17A and TNF-α.

J. Krueger, S. Garcet, Xuan Li, 2023, The Journal of investigative dermatology.

Unique protein signatures evolve during the course of a delayed‐type hypersensitivity reaction in human skin

J. Krueger, J. Correa da Rosa, Y. Estrada, 2022, Journal of dermatology (Print).

303 TYK2/JAK1 inhibition with PF-06700841 rapidly attenuates IL23/IL17 pathway genes and reverses the molecular phenotype in psoriasis

E. Peeva, M. Suárez-Fariñas, J. Krueger, 2017 .

Proteomic characterization of atopic dermatitis blood from infancy to adulthood.

A. Paller, J. Krueger, E. Guttman‐Yassky, 2023, Journal of the American Academy of Dermatology.

A phase 2a randomized, double‐blind, placebo‐controlled, sequential dose‐escalation study to evaluate the efficacy and safety of ASP015K, a novel Janus kinase inhibitor, in patients with moderate‐to‐severe psoriasis

K. Papp, G. Ball, J. Krueger, 2015, The British journal of dermatology.

Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection.

M. Suárez-Fariñas, J. Krueger, B. Ungar, 2015, The Journal of allergy and clinical immunology.

A Novel Chimeric Lysin Shows Superiority to Mupirocin for Skin Decolonization of Methicillin-Resistant and -Sensitive Staphylococcus aureus Strains

Chad W. Euler, V. Fischetti, J. Krueger, 2010, Antimicrobial Agents and Chemotherapy.

Molecular profiling of contact dermatitis skin identifies allergen-dependent differences in immune response.

M. Suárez-Fariñas, J. Krueger, I. Cardinale, 2014, The Journal of allergy and clinical immunology.

A systematic review and critical evaluation of inflammatory cytokine associations in hidradenitis suppurativa

J. Krueger, J. Frew, J. Hawkes, 2018, F1000Research.

Effective narrow-band UVB radiation therapy suppresses the IL-23/IL-17 axis in normalized psoriasis plaques.

M. Suárez-Fariñas, J. Krueger, M. Lowes, 2010, The Journal of investigative dermatology.

Evolution of pathologic T-cell subsets in atopic dermatitis from infancy to adulthood.

Hyun Je Kim, A. Paller, J. Krueger, 2020, The Journal of allergy and clinical immunology.

TNF-α Antagonist and Vascular Inflammation in Patients with Psoriasis Vulgaris: A Randomized Placebo-Controlled Study.

J. Tardif, M. Guertin, R. Bissonnette, 2017, The Journal of investigative dermatology.

Evolution of pathologic T-cell subsets in atopic dermatitis frominfancy to adulthood

Hyun Je Kim, A. Paller, J. Krueger, 2020 .

ACTIVATED PLATELETS INDUCE ENDOTHELIAL ACTIVATION IN PATIENTS WITH PSORIASIS

E. Fisher, J. Berger, Tessa J. Barrett, 2019, Journal of the American College of Cardiology.

CCL20 in Psoriasis: A Potential Biomarker of Disease Severity, Inflammation, and Impaired Vascular Health.

E. Fisher, A. Neimann, J. Berger, 2020, Journal of the American Academy of Dermatology.

Early intervention in psoriasis and immune-mediated inflammatory diseases: A hypothesis paper

P. Emery, F. Nestle, G. Girolomoni, 2015, The Journal of dermatological treatment.

Tofacitinib attenuates pathologic immune pathways in patients with psoriasis: A randomized phase 2 study.

J. D. Clark, H. Valdez, M. Suárez-Fariñas, 2016, The Journal of allergy and clinical immunology.

Psoriasis improvements and inflammatory biomarker normalization with secukinumab: the randomized ObePso-S study.

F. Kianifard, A. Blauvelt, S. Tyring, 2023, Journal of dermatological science.

Reply: To PMID 25748064.

J. Krueger, E. Guttman‐Yassky, T. Czarnowicki, 2015, The Journal of allergy and clinical immunology.

Cyclosporine A immunosuppression drives catastrophic squamous cell carcinoma through IL-22.

J. Carucci, T. Oberyszyn, D. Felsen, 2016, JCI insight.

Atopic dermatitis keratinocytes exhibit normal T(H)17 cytokine responses.

Lisa C. Zaba, R. Bergman, M. Suárez-Fariñas, 2010, The Journal of allergy and clinical immunology.

Spatial transcriptomic profiling reveals the pathophysiology of early-stage hidradenitis suppurativa.

Soyoung Jeong, Soyun Cho, J. Krueger, 2023, The British journal of dermatology.

Laser capture microdissection followed by next‐generation sequencing identifies disease‐related microRNAs in psoriatic skin that reflect systemic microRNA changes in psoriasis

M. Hafner, J. Zibert, L. Skov, 2015, Experimental dermatology.

Line scanning, stage scanning confocal microscope (LSSSCM).

J. Carucci, S. Meehan, D. Gareau, 2017, Biomedical optics express.