B. Arnold

G. Opdenakker, P. Proost, J. Van Damme, 2002, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Failure to induce organ‐specific autoimmunity by breaking of tolerance: importance of the microenvironment

J. Alferink, T. Nichterlein, G. Hämmerling, 1998, European journal of immunology.

Long life span of tolerant T cells and the role of antigen in maintenance of peripheral tolerance.

J. Alferink, G. Schönrich, G. Hämmerling, 1995, International immunology.

Inflammatory macrophages, and not only neutrophils, die by apoptosis during acute peritonitis.

B. Plytycz, E. Kolaczkowska, B. Arnold, 2010, Immunobiology.

Peripheral T‐cell tolerance: the contribution of permissive T‐cell migration into parenchymal tissues of the neonate

J. Alferink, R. Reibke, G. Hämmerling, 1999, Immunological reviews.

Mechanisms of Peripheral Tolerance

G. Schönrich, B. Malissen, F. Momburg, 1993 .

Distinct requirements of positive and negative selection for selecting cell type and CD8 interaction.

G. Schönrich, D. Loh, G. Hämmerling, 1993, Journal of immunology.

Threshold tolerance in H-2Kb-specific TCR transgenic mice expressing mutant H-2Kb: conversion of helper-independent to helper-dependent CTL.

G. Schönrich, B. Malissen, G. Hämmerling, 1992, International immunology.

Non‐Deletional Mechanisms of Peripheral and Central Tolerance: Studies with Transgenic Mice with Tissue‐Specific Expression of a Foreign MHC Class I Antigen

G. Schönrich, B. Malissen, F. Momburg, 1991, Immunological reviews.

Multiple levels of peripheral tolerance.

G. Schönrich, G. Hämmerling, B. Arnold, 1993, Immunology today.

Cutting Edge: Innate Immune Cells Contribute to the IFN-γ-Dependent Regulation of Antigen-Specific CD8+ T Cell Homeostasis1

G. Hämmerling, T. Schüler, B. Arnold, 2006, The Journal of Immunology.

Cytolytic T cells recognize the two amino-terminal domains of H-2 K antigens in tandem in influenza A infected cells

U. Hamann, U. Kees, B. Arnold, 1984, Cell.

Wnt2 acts as an angiogenic growth factor for non-sinusoidal endothelial cells and inhibits expression of stanniocalcin-1

S. Goerdt, J. Kroll, B. Arnold, 2009, Angiogenesis.

Render Autochthonous Tumors Permissive CpG Motifs as Proinflammatory Factors

S. Gordon, G. Hämmerling, N. Garbi, 2004 .

Autoaggression and tumor rejection: it takes more than self‐specific T‐cell activation

G. Hämmerling, B. Arnold, A. Limmer, 1999, Immunological reviews.

Extracellular Vesicle-Mediated Transfer of Genetic Information between the Hematopoietic System and the Brain in Response to Inflammation

P. Altevogt, K. Plate, H. Sültmann, 2014, Journal of Neuroimmunology.

Peripheral T Cell Tolerance: Distinct Levels and Multistep Mechanisms

J. Alferink, G. Schönrich, G. Hämmerling, 1994 .

The Lyt-2 accessory molecule is responsible for the weak mouse anti-HLA xeno-response.

G. Hämmerling, B. Arnold, U. Kalinke, 1990 .

IFN-g Receptor Signaling Regulates Memory CD8 T Cell Differentiation

G. Hämmerling, B. Arnold, Diana Stoycheva, 2010 .

Lymphatic endothelium‐specific hyaluronan receptor LYVE‐1 is expressed by stabilin‐1+, F4/80+, CD11b+ macrophages in malignant tumours and wound healing tissue in vivo and in bone marrow cultures in vitro: implications for the assessment of lymphangiogenesis

S. Ugurel, H. Kurzen, S. Goerdt, 2006, The Journal of pathology.

Commensal microflora and interferon‐γ promote steady‐state interleukin‐7 production in vivo

G. Willimsky, T. Blankenstein, J. Tuckermann, 2010, European journal of immunology.

Selection of phenotypically distinct NK1.1+ T cells upon antigen expression in the thymus or in the liver

G. Hämmerling, S. Guerder, B. Arnold, 1999, European journal of immunology.

Anergy induced by thymic medullary epithelium

G. Schönrich, F. Momburg, G. Hämmerling, 1992, European journal of immunology.

Mechanisms of Extrathymic Tolerance

G. Schönrich, G. Hämmerling, B. Arnold, 1993 .

Strong xenogeneic HLA response in transgenic mice after introducing an α3 domain into HLA B27

G. Hämmerling, B. Arnold, U. Kalinke, 1990, Nature.

Deficiency of gelatinase B/MMP-9 aggravates lpr-induced lymphoproliferation and lupus-like systemic autoimmune disease.

B. Cauwe, P. E. Van den Steen, G. Opdenakker, 2011, Journal of autoimmunity.

Angiocrine Bmp2 signaling in murine liver controls normal iron homeostasis.

Thomas Leibing, S. Goerdt, B. Spencer‐Dene, 2017, Blood.

Clonal Deletion of Autospecific B Lymphocytes

G. Morahan, D. Nemazee, J. Miller, 1991, Immunological reviews.

Nck adaptor proteins modulate differentiation and effector function of T cells

T. Pawson, T. Mattfeldt, F. Leithäuser, 2015, Journal of leukocyte biology.

Peripheral Tolerance as a Multi‐Step Mechanism

G. Schönrich, G. Hämmerling, B. Arnold, 1993, Immunological reviews.

Antigen presentation by MHC class II molecules : Role of the accessory MHC molecules HLA-DM and HLA-DO ( G 0400-2 )

R. Reibke, G. Hämmerling, T. Schüler, 2003 .

The actin remodeling protein cofilin is crucial for thymic αβ but not γδ T-cell development

Y. Samstag, D. De Stefano, B. Jahraus, 2018, PLoS biology.

Cytolytic T Cells Recognize Conformational Determinants of H-2 K Antigens in Influenza A-Infected Cells

B. Arnold, H. Burgert, S. Kvist, 1985 .

Alloreactive cytolytic T-cell clones preferentially recognize conformational determinants on histocompatibility antigens: analysis with genetically engineered hybrid antigens.

G. Hämmerling, B. Arnold, H. Burgert, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Complete nucleotide sequence of the murine H-2Kk gene. Comparison of three H-2K locus alleles.

A. Archibald, B. Arnold, H. Burgert, 1984, Nucleic acids research.

Distinct mechanisms of extrathymic T cell tolerance due to differential expression of self antigen.

G. Schönrich, B. Malissen, F. Momburg, 1992, International immunology.

Structural comparison of I-A antigens produced by a cloned murine T suppressor cell line with B-Cell-Derived I-A

G. Hämmerling, B. Arnold, E. Kölsch, 2004, Immunogenetics.

Parenchymal cells in immune and tolerance induction.

B. Arnold, 2003, Immunology letters.

A two-step model for the induction of organ-specific autoimmunity.

J. Alferink, T. Nichterlein, G. Hämmerling, 1998, Novartis Foundation symposium.

Release of High Mobility Group Box 1 by Dendritic Cells Controls T Cell Activation via the Receptor for Advanced Glycation End Products1

Peter P. Nawroth, Bernd Arnold, M. Bianchi, 2005, The Journal of Immunology.

Tolerance induction as a multi‐step process

J. Alferink, G. Schönrich, G. Hämmerling, 1994, European journal of immunology.

Tolerance induction in mature peripheral T cells

J. Alferink, G. Schönrich, G. Hämmerling, 1994 .

Cutting Edge: Innate Lymphoid Cells Suppress Homeostatic T Cell Expansion in Neonatal Mice

G. Hämmerling, T. Schüler, B. Arnold, 2016, The Journal of Immunology.

Stimulation of autoimmunity by toll-like receptor ligands

G. Hämmerling, N. Garbi, B. Arnold, 2005, Annals of the rheumatic diseases.

Induction and Breaking of Peripheral Tolerance

J. Alferink, G. Hämmerling, B. Arnold, 1996 .

Extrathymic T-cell selection.

G. Schönrich, G. Hämmerling, B. Arnold, 1992 .

TLR-4 ligation of dendritic cells is sufficient to drive pathogenic T cell function in experimental autoimmune encephalomyelitis

M. Leech, S. Anderton, B. Arnold, 2012, Journal of Neuroinflammation.

Explorer TLR4 ligation of dendritic cells is sufficient to drive pathogenic T cell function in experimental autoimmune encephalomyelitis

M. Leech, S. Anderton, B. Arnold, 2012 .

Resident peritoneal leukocytes are important sources of MMP-9 during zymosan peritonitis: superior contribution of macrophages over mast cells.

B. Plytycz, N. Van Rooijen, E. Kolaczkowska, 2007, Immunology letters.

Enhanced early vascular permeability in gelatinase B (MMP‐9)‐deficient mice: putative contribution of COX‐1‐derived PGE2 of macrophage origin

B. Plytycz, G. Opdenakker, N. Rooijen, 2006, Journal of leukocyte biology.

Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line

Rainer Constien, H. Gröne, P. Nawroth, 2001, Genesis.

Fate and Function Dickkopf-3 Acts as a Modulator of B Cell

H. Gröne, L. Nitschke, B. Arnold, 2015 .

Natural Memory T Cells Mice Allows the Generation of Long-Lived T Cells in Neonatal + Proliferation of CD8 Cutting Edge: IL-7-Dependent Homeostatic

G. Hämmerling, T. Schüler, B. Arnold, 2003 .

Unrestricted recognition of class I neodeterminants generated by exon shuffling

G. Hämmerling, B. Arnold, U. Horstmann, 1986, European journal of immunology.

Alloreactive immune responses of transgenic mice expressing a foreign transplantation antigen in a soluble form.

M. Simon, B. Arnold, J. Tucker, 1988, Proceedings of the National Academy of Sciences of the United States of America.

A Con A-stimulated T-cell hybridoma releases factors affecting haematopoietic colony-forming cells and B-cell antibody responses

J. Schrader, B. Arnold, I. Clark‐Lewis, 1980, Nature.

Antibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT

P. Altevogt, U. Haberkorn, M. Mittelbronn, 2015, International journal of cancer.

Inhibitors of animal phospholipase A2 enzymes are selective inhibitors of auxin-dependent growth. Implications for auxin-induced signal transduction

B. Arnold, G. Scherer, 1997, Planta.

Nck adaptors are positive regulators of the size and sensitivity of the T-cell repertoire

T. Pawson, A. Kopp-Schneider, P. Möller, 2010, Proceedings of the National Academy of Sciences.

The hormetic functions of Wnt pathways in tubular injury

H. Gröne, P. Nelson, B. Arnold, 2017, Pflügers Archiv - European Journal of Physiology.

Wnt2 acts as a cell type–specific, autocrine growth factor in rat hepatic sinusoidal endothelial cells cross‐stimulating the VEGF pathway

S. Goerdt, H. Augustin, J. Kroll, 2008, Hepatology.

A non-enzymatic function of 17β-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival

K. Kavanagh, R. Wanders, C. Bartram, 2010, EMBO molecular medicine.

Understanding RAGE, the receptor for advanced glycation end products

D. Stern, P. Nawroth, A. Bierhaus, 2005, Journal of Molecular Medicine.

Neutrophil elastase activity compensates for a genetic lack of matrix metalloproteinase‐9 (MMP‐9) in leukocyte infiltration in a model of experimental peritonitis

B. Plytycz, G. Opdenakker, N. Rooijen, 2009, Journal of leukocyte biology.

Vascular targeting of anti-CD40 antibodies and IL-2 into autochthonous tumors enhances immunotherapy in mice.

G. Hämmerling, J. Hamzah, B. Arnold, 2008, The Journal of clinical investigation.

Dickkopf-3, a Tissue-Derived Modulator of Local T-Cell Responses

Kathy O. Lui, Maria Papatriantafyllou, M. Meister, 2015, Front. Immunol..

CpG‐ODN‐induced inflammation is sufficient to cause T‐cell‐mediated autoaggression against hepatocytes

T. Nichterlein, P. Knolle, G. Hämmerling, 2002, European journal of immunology.

Differential expression of a gene signature for scavenger/lectin receptors by endothelial cells and macrophages in human lymph node sinuses, the primary sites of regional metastasis

S. Goerdt, U. Mansmann, A. Gratchev, 2006 .

Lysolecithin analogs as adjuvants in delayed‐type hypersensitivity in mice. II. Studies on the mode of action

B. Arnold, Jacques F. Miller, F. Staber, 1979, European journal of immunology.

Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction

G. Schönrich, B. Malissen, F. Momburg, 1991, Cell.

Neutralizing antibodies in gene-defective hosts.

P. E. Van den Steen, G. Opdenakker, B. Arnold, 2003, Trends in immunology.

Brain development in mice lacking L1–L1 homophilic adhesion

P. Altevogt, H. Kamiguchi, V. Lemmon, 2004, The Journal of cell biology.

GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis

Thomas Leibing, S. Goerdt, H. Augustin, 2017, The Journal of clinical investigation.

Interleukin-7 Links T Lymphocyte and Intestinal Epithelial Cell Homeostasis

C. Loddenkemper, A. Kühl, M. Fromm, 2012, PloS one.

The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase

David E. Strochlic, S. Liberles, M. Devor, 2015, Nature Medicine.

RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain

Ann Marie Schmidt, Berislav Zlokovic, David Stern, 2003, Nature Medicine.

Cross‐presentation of oral antigens by liver sinusoidal endothelial cells leads to CD8 T cell tolerance

F. Momburg, P. Knolle, G. Hämmerling, 2005, European journal of immunology.

Vascular normalization in Rgs5-deficient tumours promotes immune destruction

Fabian Kiessling, Juliana Hamzah, Ruth Ganss, 2008, Nature.

T Cell Awareness of Paternal Alloantigens During Pregnancy

J. Alferink, P. Möller, G. Hämmerling, 1995, Science.

Gelatinase B deficiency protects against endotoxin shock

G. Opdenakker, B. Dubois, B. Arnold, 2002, European journal of immunology.

JunB is required for endothelial cell morphogenesis by regulating core-binding factor β

P. Lichter, P. Angel, B. Arnold, 2006, The Journal of cell biology.

Levels of peripheral T cell tolerance induced by different doses of tolerogen.

G. Schönrich, G. Hämmerling, A. Mellor, 1994, Science.

Brief OeNnitive Report

B. Arnold, G. Hammerling, R. Wallich, 2003 .

Elicitation of delayed-type hypersensitivity to phosphorylcholine by monoclonal anti-idiotypic antibodies in an allogeneic environment

G. Hämmerling, B. Arnold, R. Wallich, 1982, The Journal of experimental medicine.

Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication.

G. Hämmerling, B. Arnold, E. Ryschich, 2002, Cancer research.

Tubular Dickkopf-3 promotes the development of renal atrophy and fibrosis.

T. Hielscher, A. Kopp-Schneider, D. Fliser, 2016, JCI insight.

Fine Tuning of the Threshold of T Cell Selection by the Nck Adapters

T. Pawson, A. Kopp-Schneider, P. Möller, 2010, The Journal of Immunology.

This information is current as Selection by the Nck Adapters Fine Tuning of the Threshold of T Cell

Tony Pawson, Sabine Schmitt, Bernd Arnold, 2010 .

CD166/ALCAM Mediates Proinflammatory Effects of S100B in Delayed Type Hypersensitivity

A. Hotz-Wagenblatt, H. Gröne, D. Stern, 2013, The Journal of Immunology.

Distinct mechanisms of peripheral tolerance in transgenic mice.

G. Schönrich, B. Malissen, F. Momburg, 1991, Research in immunology.

Dickkopf-3, an immune modulator in peripheral CD8 T-cell tolerance

C. Niehrs, Maria Papatriantafyllou, H. Gröne, 2012, Proceedings of the National Academy of Sciences.

CpG Motifs as Proinflammatory Factors Render Autochthonous Tumors Permissive for Infiltration and Destruction1

S. Gordon, G. Hämmerling, N. Garbi, 2004, The Journal of Immunology.

The Pattern Recognition Receptor (RAGE) Is a Counterreceptor for Leukocyte Integrins

K. Preissner, P. Nawroth, A. Bierhaus, 2003, The Journal of experimental medicine.

Tumor agonist peptides break tolerance and elicit effective CTL responses in an inducible mouse model of hepatocellular carcinoma.

G. Hämmerling, U. Protzer, N. Garbi, 2009, Immunology letters.

Receptor for advanced glycation endproducts (RAGE) is a key regulator of oval cell activation and inflammation‐associated liver carcinogenesis in mice

Angelika Bierhaus, Thomas Longerich, Bernd Arnold, 2013, Hepatology.

RAGE signaling sustains inflammation and promotes tumor development

A. Enk, P. Angel, J. Hess, 2008, The Journal of experimental medicine.

Influence of antigen density on degree of clonal deletion in T cell receptor transgenic mice.

G. Schönrich, B. Malissen, G. Hämmerling, 1992, International immunology.

Expression of major histocompatibility complex class I antigens at low levels in the thymus induces T cell tolerance via a non‐deletional mechanism

A. Cooke, G. Schönrich, K. Philpott, 1992, European journal of immunology.

Differential expression of a gene signature for scavenger/lectin receptors by endothelial cells and macrophages in human lymph node sinuses, the primary sites of regional metastasis.

S. Goerdt, U. Mansmann, A. Gratchev, 2006, The Journal of pathology.

NK- and CD8+ T Cell-Mediated Eradication of Established Tumors by Peritumoral Injection of CpG-Containing Oligodeoxynucleotides1

Y. Kawarada, G. Hämmerling, N. Garbi, 2001, The Journal of Immunology.

CD95 Ligand-Expressing Tumors Are Rejected in Anti-Tumor TCR Transgenic Perforin Knockout Mice

P. Krammer, B. Arnold, Christian K. Behrens, 2001, The Journal of Immunology.

Perforin Knockout Mice Rejected in Anti-Tumor TCR Transgenic CD 95 Ligand-Expressing Tumors Are

P. Möller, P. Krammer, B. Arnold, 2001 .

Temporal Cre‐mediated recombination exclusively in endothelial cells using Tie2 regulatory elements

Rainer Constien, H. Gröne, G. Hämmerling, 2002, Genesis.

Regulator of G-protein signaling-5 induction in pericytes coincides with active vessel remodeling during neovascularization.

G. Bergers, G. Hämmerling, B. Arnold, 2005, Blood.

A role for Th2 cytokines in the suppression of CD8+ T cell‐mediated graft rejection

S. Cobbold, A. Mellor, B. Arnold, 1997, European journal of immunology.

Innate immune cells contribute to the IFN-gamma-dependent regulation of antigen-specific CD8+ T cell homeostasis.

G. Hämmerling, T. Schüler, B. Arnold, 2006, Journal of immunology.

Triggering of T-cell leukemia and dissemination of T-cell lymphoma in MMP-9-deficient mice

G. Opdenakker, Y. St-Pierre, B. Arnold, 2007, Leukemia.

Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors.

S. Goerdt, P. Schirmacher, H. Gröne, 2011, The Journal of clinical investigation.

Altered apoptosis of inflammatory neutrophils in MMP-9-deficient mice is due to lower expression and activity of caspase-3.

B. Plytycz, G. Opdenakker, E. Kolaczkowska, 2009, Immunology letters.

Advanced Glycation End Product Receptor‐Mediated Cellular Dysfunction

D. Stern, P. Nawroth, A. Bierhaus, 2005, Annals of the New York Academy of Sciences.

Central role of RAGE-dependent neointimal expansion in arterial restenosis.

M. Andrassy, M. Sousa, A. Schmidt, 2003, The Journal of clinical investigation.

In vivo neutrophil recruitment by granulocyte chemotactic protein-2 is assisted by gelatinase B/MMP-9 in the mouse.

G. Opdenakker, A. Billiau, B. Dubois, 2000, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Nuclear Localization of Suppressor of Cytokine Signaling-1 Regulates Local Immunity in the Lung

F. Lasitschka, C. Vock, B. Arnold, 2016, Front. Immunol..

Gelatinase B deficiency impairs reproduction.

G. Opdenakker, B. Dubois, B. Arnold, 2000, The Journal of clinical investigation.

Inhibition of gelatinase B/MMP-9 does not attenuate colitis in murine models of inflammatory bowel disease

S. Vermeire, M. Ferrante, G. Van Assche, 2017, Nature Communications.

Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding protein.

P. Gass, G. Schütz, D. Rudolph, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Expression of LYVE-1 by stabilin-1+, F4/80+, CD11B+ macrophages in malignant tumours and wound healing tissue indicates a contribution of endothelial-like macrophages to lymphatic vessels during lymphangiogenesis

S. Goerdt, M. Falkowski, P. Metharom, 2006 .

Cutting Edge: IL-7-Dependent Homeostatic Proliferation of CD8+ T Cells in Neonatal Mice Allows the Generation of Long-Lived Natural Memory T Cells 1

G. Hämmerling, T. Schüler, B. Arnold, 2004, The Journal of Immunology.

Gelatinase B/matrix metalloproteinase-9 contributes to cellular infiltration in a murine model of zymosan peritonitis.

B. Plytycz, G. Opdenakker, E. Kolaczkowska, 2006, Immunobiology.

The hormetic functions of Wnt pathways in tubular injury

H. Gröne, P. Nelson, B. Arnold, 2017, Pflügers Archiv - European Journal of Physiology.

An improved method for selecting T-cell hybridomas by the fluorescence-activated cell sorter.

B. Arnold, F. Battye, J. Miller, 1979, Journal of immunological methods.

Transgenic mice expressing a soluble foreign H-2 class I antigen are tolerant to allogeneic fragments presented by self class I but not to the whole membrane-bound alloantigen.

U. Koszinowski, M. Messerle, B. Arnold, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Increased cyclooxygenase activity impairs apoptosis of inflammatory neutrophils in mice lacking gelatinase B/matrix metalloproteinase‐9

B. Plytycz, G. Opdenakker, E. Kolaczkowska, 2009, Immunology.

Tolerance induction in mature T lymphocytes.

J. Alferink, G. Hämmerling, B. Arnold, 1998, Novartis Foundation symposium.

Mast cell involvement in zymosan-induced peritonitis in C57Bl/6 mice

B. Arnold, 2008 .

Disrupted Schwann cell–axon interactions in peripheral nerves of mice with altered L1-integrin interactions

P. Altevogt, H. Kamiguchi, V. Lemmon, 2005, Molecular and Cellular Neuroscience.

T cell activation and thymic tolerance induction require different adhesion intensities of the CD8 co-receptor.

G. Schönrich, B. Malissen, J. Schenkel, 1992, International immunology.

Strong xenogeneic HLA response in transgenic mice after introducing an alpha 3 domain into HLA B27.

G. Hämmerling, B. Arnold, U. Kalinke, 1990, Nature.

Glucose, glycation, and RAGE: implications for amplification of cellular dysfunction in diabetic nephropathy.

V. D’Agati, R. Ramasamy, A. Schmidt, 2003, Journal of the American Society of Nephrology : JASN.