J. Stone

发表

Different thermodynamic binding mechanisms and peptide fine specificities associated with a panel of structurally similar high-affinity T cell receptors.

K. Garcia, D. Kranz, L. A. Colf, 2008, Biochemistry.

HLA-restricted epitope identification and detection of functional T cell responses by using MHC-peptide and costimulatory microarrays.

J. Stone, L. Stern, W. Demkowicz, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Role of T Cell Receptor Affinity in the Efficacy and Specificity of Adoptive T Cell Therapies

David M. Kranz, Jennifer D. Stone, D. Kranz, 2013, Front. Immunol..

TCR: losing its inhibitions?

J. Cochran, J. Stone, L. Stern, 2001, Trends in immunology.

Receptor Proximity, Not Intermolecular Orientation, Is Critical for Triggering T-cell Activation*

J. Cochran, J. Stone, L. Stern, 2001, The Journal of Biological Chemistry.

Exploration of the P6/P7 Region of the Peptide-binding Site of the Human Class II Major Histocompatability Complex Protein HLA-DR1*

Jennifer D. Stone, Daniel B. DeOliveira, Eric J. Sundberg, 2003, Journal of Biological Chemistry.

Soluble peptide–MHC monomers cause activation of CD8+ T cells through transfer of the peptide to T cell MHC molecules

Jianzhu Chen, J. Cochran, Q. Ge, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Interaction of Streptavidin-Based Peptide–MHC Oligomers (Tetramers) with Cell-Surface TCRs

Maxim N. Artyomov, A. Chakraborty, D. Kranz, 2011, The Journal of Immunology.

Interaction of Streptavidin-Based Peptide-MHC Oligomers (Tetramers) with Cell-Surface T Cell Receptors

Maxim N. Artyomov, A. Chakraborty, D. Kranz, 2011 .

Cell-Surface TCRs MHC Oligomers (Tetramers) with - Interaction of Streptavidin-Based Peptide

Maxim N. Artyomov, A. Chakraborty, D. Kranz, 2011 .

T cells use rafts for survival.

D. Kranz, J. Stone, 2010, Immunity.

Aberrant TCR-mediated signaling in CD45-null thymocytes involves dysfunctional regulation of Lck, Fyn, TCR-zeta, and ZAP-70.

D. Alexander, J. Stone, N. Holmes, 1997, Journal of immunology.

CD8 T Cells, Like CD4 T Cells, Are Triggered by Multivalent Engagement of TCRs by MHC-Peptide Ligands but Not by Monovalent Engagement1

J. Stone, L. Stern, 2006, The Journal of Immunology.

Monovalent Engagement TCRs by MHC-Peptide Ligands but Not by Triggered by Multivalent Engagement of CD8 T Cells, Like CD4 T Cells, Are

J. Stone, L. Stern, 2006 .

MHC-class I-restricted CD4 T cells: a nanomolar affinity TCR has improved anti-tumor efficacy in vivo compared to the micromolar wild-type TCR

D. Kranz, B. Engels, E. Roy, 2013, Cancer Immunology, Immunotherapy.

Design and characterization of a protein superagonist of IL‐15 fused with IL‐15Rα and a high‐affinity T cell receptor

H. Schreiber, J. Stone, A. Chervin, 2012, Biotechnology progress.

Opposite Effects of Endogenous Peptide–MHC Class I on T Cell Activity in the Presence and Absence of CD8

Thomas M. Schmitt, P. Greenberg, D. Kranz, 2011, The Journal of Immunology.

Biosensor detection systems: engineering stable, high-affinity bioreceptors by yeast surface display.

D. Kranz, J. Stone, S. Richman, 2009, Methods in molecular biology.

Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma.

Alexandria P. Cogdill, C. June, M. Feldman, 2016, Immunity.

Comparison of T Cell Activities Mediated by Human TCRs and CARs That Use the Same Recognition Domains

Thomas M. Schmitt, P. Greenberg, D. Kranz, 2018, The Journal of Immunology.

A sensitivity scale for targeting T cells with chimeric antigen receptors (CARs) and bispecific T-cell Engagers (BiTEs)

D. Kranz, H. Schreiber, J. Stone, 2012, Oncoimmunology.

T‐cell receptor binding affinities and kinetics: impact on T‐cell activity and specificity

D. Kranz, J. Stone, A. Chervin, 2009, Immunology.

A Multiplex Assay for Detection of Staphylococcal and Streptococcal Exotoxins

D. Kranz, J. Stone, A. Chervin, 2015, PLoS ONE.

Studies on the molecular mechanism of T cell triggering and detection and characterization of antigen-specific T cells

J. Stone, 2004 .

Breaking tolerance with engineered class I antigen-presenting molecules

L. Pease, D. Kranz, M. Barry, 2019, Proceedings of the National Academy of Sciences.

Noble metals strip peptides from class II MHC proteins

Timothy J Mitchison, D. Wiley, B. DeDecker, 2006, Nature chemical biology.

TCR affinity for p/MHC formed by tumor antigens that are self-proteins: impact on efficacy and toxicity.

David M Kranz, D. Kranz, J. Stone, 2015, Current opinion in immunology.

Single-chain VαVβ T-cell receptors function without mispairing with endogenous TCR chains

Thomas M. Schmitt, B. Baker, P. Greenberg, 2011, Gene Therapy.

T-cell activation by soluble MHC oligomers can be described by a two-parameter binding model.

J. Cochran, J. Stone, L. Stern, 2001, Biophysical journal.

Antagonism of HIV-specific CD4+ T cells by C-terminal truncation of a minimum epitope.

B. Walker, J. Stone, H. Moffett, 2006, Molecular immunology.

A novel T cell receptor single-chain signaling complex mediates antigen-specific T cell activity and tumor control

D. Kranz, E. Roy, J. Stone, 2014, Cancer Immunology, Immunotherapy.

T-cell Receptors Engineered De Novo for Peptide Specificity Can Mediate Optimal T-cell Activity without Self Cross-Reactivity

D. Kranz, J. Stone, D. Harris, 2019, Cancer Immunology Research.

Cutting Edge: Inhibitory Effects of CD4 and CD8 on T Cell Activation Induced by High-Affinity Noncognate Ligands1

D. Kranz, J. Stone, A. Chervin, 2009, The Journal of Immunology.

The Impact of TCR-Binding Properties and Antigen Presentation Format on T Cell Responsiveness1

Jianzhu Chen, D. Kranz, H. Eisen, 2009, The Journal of Immunology.

ResponsivenessAntigen Presentation Format on T Cell The Impact of TCR-Binding Properties and

Jianzhu Chen, D. Kranz, H. Eisen, 2009 .

This information is current as High-Affinity Noncognate Ligands CD 8 on T Cell Activation Induced by Cutting Edge : Inhibitory Effects of CD 4 and and

D. Kranz, J. Stone, A. Chervin, 2009 .

Distinct CDR3 Conformations in TCRs Determine the Level of Cross-Reactivity for Diverse Antigens, but Not the Docking Orientation1

David M. Kranz, Jennifer D. Stone, K. Christopher Garcia, 2008, The Journal of Immunology.

Design of T cell receptor libraries with diverse binding properties to examine adoptive T cell responses

D. Kranz, B. Engels, E. Roy, 2012, Gene Therapy.

This information is current as Recognition Domains Human TCRs and CARs That Use the Same Comparison of T Cell Activities Mediated by

Thomas M. Schmitt, P. Greenberg, D. Kranz, 2017 .

Tar geting the Cancer-AssociatedTn-Glycoformof theMembraneMucinMUC 1 Control Adenocarcinoma Highlights

David M. Kranz, Jennifer D. Stone, Brian Keith, 2016 .

T cell receptor engineering.

D. Kranz, J. Stone, A. Chervin, 2012, Methods in enzymology.

CD8 T cells, like CD4 T cells, are triggered by multivalent engagement of TCRs by MHC-peptide ligands but not by monovalent engagement.

J. Stone, L. Stern, 2006, The Journal of Immunology.

Engineering High-Affinity T Cell Receptor/ Cytokine Fusions for Therapeutic Targeting

P. Allen, R. Mariuzza, D. Kranz, 2012 .

Tyrosine phosphatases in T-cell development and signalling.

D. Alexander, J. Frearson, J. Stone, 1997, Biochemical Society Transactions.

T‐cell receptor binding affinities and kinetics: impact on T‐cell activity and specificity

D. Kranz, J. Stone, A. Chervin, 2009, Immunology.