K. Kawashima

J. Hatazawa, K. Ishiwata, K. Hatano, 1990, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

Nicotine-induced Ca2+ signaling and down-regulation of nicotinic acetylcholine receptor subunit expression in the CEM human leukemic T-cell line.

K. Kawashima, T. Fujii, N. Ushiyama, 2003, Life sciences.

Studies on 18F-labeled pyrimidines

M. Murakami, K. Ishiwata, T. Ido, 1984, European Journal of Nuclear Medicine.

A comparison of radioimmunoassay with spectrophotometry for the determination of plasma diphenylhydantoin concentrations.

K. Kawashima, B. Ishijima, N. Yoshimizu, 1980, Japanese journal of pharmacology.

Synthesis and release of acetylcholine by cultured bovine arterial endothelial cells

I. Morita, S. Murota, K. Kawashima, 1990, Neuroscience Letters.

Extraneuronal localization of acetylcholine and its release upon nicotinic stimulation in rabbits

K. Kawashima, K. Fujimoto, Takeshi Suzuki, 1989, Neuroscience Letters.

Acetylcholine released from T cells regulates intracellular Ca2+, IL‐2 secretion and T cell proliferation through nicotinic acetylcholine receptor

K. Kawashima, Masato Mashimo, T. Fujii, 2017, Life sciences.

Radioimmunoassay for acetylcholine in the rat brain.

K. Kawashima, H. Ishikawa, M. Mochizuki, 1980, Journal of pharmacological methods.

Radioimmunoassay for reserpine.

K. Kawashima, S. Spector, A. Levy, 1976, Life sciences.

Non-neuronal neurotransmitters and neurotrophic factors in amniotic epithelial cells: expression and function in humans and monkey.

K. Kawashima, N. Sakuragawa, M. Elwan, 2001, Japanese journal of pharmacology.

Expression of non-neuronal acetylcholine in lymphocytes and its contribution to the regulation of immune function.

K. Kawashima, T. Fujii, 2004, Frontiers in bioscience : a journal and virtual library.

The lymphocytic cholinergic system and its contribution to the regulation of immune activity.

K. Kawashima, Koichiro Kawashima, Takeshi Fujii, 2003, Life sciences.

Extraneuronal cholinergic system in lymphocytes.

K. Kawashima, T. Fujii, 2000, Pharmacology & therapeutics.

Diversity of mRNA expression for muscarinic acetylcholine receptor subtypes and neuronal nicotinic acetylcholine receptor subunits in human mononuclear leukocytes and leukemic cell lines

Kazuo Z. Sato, K. Kawashima, Tsuyoshi Ando, 1999, Neuroscience Letters.

Constitutive expression of mRNA for the same choline acetyltransferase as that in the nervous system, an acetylcholine-synthesizing enzyme, in human leukemic T-cell lines

Kazuo Z. Sato, K. Kawashima, T. Kasahara, 1999, Neuroscience Letters.

Acetylcholine synthesis and muscarinic receptor subtype mRNA expression in T-lymphocytes.

Y. Watanabe, K. Kawashima, H. Misawa, 1998, Life sciences.

Determination of rat pineal gland melatonin content by a radioimmunoassay.

R. Miller, K. Kawashima, S. Spector, 1976, Life sciences.

Pharmacological studies on Puerariae Flos. IV: Effects of Pueraria thomsonii dried flower extracts on blood ethanol and acetaldehyde levels in humans.

T. Nohara, K. Kawashima, Y. Matsushita, 2002, International journal of clinical pharmacology research.

Aberrant trafficking of the high‐affinity choline transporter in AP‐3‐deficient mice

R. Blakely, Takashi Nishimura, H. Ohno, 2008, The European journal of neuroscience.

Demonstration of the facilitatory role of 8-OH-DPAT on cholinergic transmission in the rat hippocampus using in vivo microdialysis

K. Kawashima, T. Fujii, K. Nakai, 1997, Brain Research.

2-Deoxy-2-[18F]fluoro-D-galactose as an in vivo tracer for imaging galactose metabolism in tumors with positron emission tomography.

K. Ishiwata, H. Fukuda, M. Kameyama, 1989, International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology.

Detection of the high-affinity choline transporter in the MOLT-3 human leukemic T-cell line.

T. Haga, K. Kawashima, T. Okuda, 2003, Life sciences.

A historic perspective on the current progress in elucidation of the biologic significance of non-neuronal acetylcholine.

K. Kawashima, S. Grando, I. Wessler, 2020, International immunopharmacology.

Localization and synthesis of acetylcholine in human leukemic T cell lines

K. Kawashima, T. Kasahara, T. Suzuki, 1996, Journal of neuroscience research.

Expression and Function of the Cholinergic System in Immune Cells

K. Kawashima, S. Ono, H. Misawa, 2017, Front. Immunol..

Physiological functions of the cholinergic system in immune cells.

K. Kawashima, S. Ono, H. Misawa, 2017, Journal of pharmacological sciences.

Reconciling neuronally and nonneuronally derived acetylcholine in the regulation of immune function

K. Kawashima, H. Misawa, Y. Moriwaki, 2012, Annals of the New York Academy of Sciences.

Critical roles of acetylcholine and the muscarinic and nicotinic acetylcholine receptors in the regulation of immune function.

K. Kawashima, Koichiro Kawashima, Takeshi Fujii, 2012, Life sciences.

Effects of some anti-inflammatory drugs on capillary permeability of the gastric mucosa in the rat.

K. Kawashima, K. Takagi, 1969, Japanese journal of pharmacology.

Expression and function of genes encoding cholinergic components in murine immune cells.

K. Kawashima, H. Misawa, Y. Moriwaki, 2007, Life sciences.

Rat lymphocytes produce and secrete acetylcholine in dependence of differentiation and activation

K. Schauenstein, K. Kawashima, I. Rinner, 1998, Journal of Neuroimmunology.

Enhanced glucose metabolism and impaired placental function in hypoxic pregnant rats.

K. Ishiwata, T. Matsuzaka, T. Ido, 1988, International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology.

Antihypertensive action of melatonin in the spontaneously hypertensive rat.

H. Nishino, K. Kawashima, H. Koike, 1987, Clinical and experimental hypertension. Part A, Theory and practice.

Melatonin in serum and the pineal of spontaneously hypertensive rats.

K. Kawashima, S. Spector, R. Wurzburger, 1984, Clinical and experimental hypertension. Part A, Theory and practice.

IMPROVEMENT OF RADIOIMMUNOASSAY FOR SERUM AND TISSUE MELATONIN

K. Kawashima, A. Nagakura, 1982 .

The effect of propranolol on the stress and Shay ulcerations in rats.

K. Kawashima, S. Okabe, R. Saziki, 1969, Japanese Journal of Pharmacology.

Oral administration of KW-5092, a novel gastroprokinetic agent with acetylcholinesterase inhibitory and acetylcholine release enhancing activities, causes a dose-dependent increase in the blood acetylcholine content of beagle dogs

K. Kawashima, T. Fujii, S. Yamada, 1997, Neuroscience Letters.

Pharmacological differentiation of presynaptic M1 muscarinic receptors modulating acetylcholine release from postsynaptic muscarinic receptors in guinea-pig ileum.

K. Kawashima, T. Suzuki, K. Fujimoto, 1990, General pharmacology.

Structure and hypotensive activity relationships of tetrandrine derivatives in stroke-prone spontaneously hypertensive rats.

T. Hayakawa, K. Kawashima, T. Suzuki, 1990, General pharmacology.

Direct determination of acetylcholine release by radioimmunoassay and presence of presynaptic M1 muscarinic receptors in guinea pig ileum.

K. Kawashima, T. Suzuki, K. Fujimoto, 1988, The Journal of pharmacology and experimental therapeutics.

Possible involvement of an impaired baroreflex mechanism but not the renin-angiotensin system and vasopressin in the enhanced pressor responsiveness to physostigmine in spontaneously hypertensive rats.

K. Kawashima, K. Fujimoto, Y. Miwa, 1987, General pharmacology.

The non-neuronal cholinergic system: basic science, therapeutic implications and new perspectives.

C. Kirkpatrick, K. Kawashima, S. Grando, 2012, Life sciences.

Non-neuronal cholinergic system in regulation of immune function with a focus on α7 nAChRs.

K. Kawashima, H. Misawa, Y. Moriwaki, 2015, International immunopharmacology.

Primary sensory neuronal expression of SLURP-1, an endogenous nicotinic acetylcholine receptor ligand

S. Waguri, K. Kawashima, T. Okuda, 2009, Neuroscience Research.

Stereospecific radioimmunoassay for propranolol isomers.

K. Kawashima, S. Spector, A. Levy, 1976, The Journal of pharmacology and experimental therapeutics.

L347P PINK1 mutant that fails to bind to Hsp90/Cdc37 chaperones is rapidly degraded in a proteasome-dependent manner

S. Endo, R. Takahashi, K. Kawashima, 2008, Neuroscience Research.

α7 nAChRs expressed on antigen presenting cells are insensitive to the conventional antagonists α-bungarotoxin and methyllycaconitine.

K. Kawashima, S. Ono, Masato Mashimo, 2020, International Immunopharmacology.

The endogenous, immunologically active peptide apelin inhibits lymphocytic cholinergic activity during immunological responses

K. Kawashima, T. Fujii, Yoko Horiuchi, 2003, Journal of Neuroimmunology.

Morphological features and healing of stress ulcers induced by alcohol and restraint.

G. Glass, K. Kawashima, R. Lev, 1976, Archives of pathology & laboratory medicine.

Effects of co-dergocrine mesylate (Hydergine) in multi-infarct dementia as evaluated by positron emission tomography.

J. Hatazawa, M. Itoh, K. Kogure, 1990, Tohoku journal of experimental medicine.

CYP2A6 polymorphisms are associated with nicotine dependence and influence withdrawal symptoms in smoking cessation

Makiko Maeda, J. Azuma, T. Fukuda, 2006, The Pharmacogenomics Journal.

Novel analogs of choline as potential neuroprotective agents.

J. Buccafusco, E. Arias, K. Kawashima, 2005, Journal of Alzheimer's disease : JAD.

Effect of secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related peptide-1 (SLURP-1) on airway epithelial cells.

S. Ishii, T. Nakahari, K. Kawashima, 2013, Biochemical and biophysical research communications.

11C-Coenzyme Q10: A new myocardial imaging tracer for positron emission tomography

K. Ishiwata, K. Yanai, T. Ido, 2004, European Journal of Nuclear Medicine.

Development of radioimmunoassay for chlorpromazine.

K. Kawashima, S. Spector, R. Dixon, 1975, European journal of pharmacology.

Disposition of oxprenolol in spontaneously hypertensive rats as determined by an enzyme immunoassay.

K. Kawashima, 1981, Journal of pharmacobio-dynamics.

[3H]2-(4-Phenylpiperidino)cyclohexanol (AH5183) binding to synaptosomes and subcellular fractions obtained from rat brain

K. Kawashima, K. Fujimoto, Takeshi Suzuki, 1993, Neuroscience Letters.

Nicotine-induced NO-mediated increase in cortical cerebral blood flow is blocked by β2-adrenoceptor antagonists in the anesthetized rats

K. Kawashima, S. Uchida, Tony J.‐F. Lee, 2002, Autonomic Neuroscience.

Effect of WAY-100135 on the hippocampal acetylcholine release potentiated by 8-OH-DPAT, a serotonin1A receptor agonist, in normal and p-chlorophenylalanine-treated rats as measured by in vivo microdialysis

K. Kawashima, T. Fujii, K. Nakai, 1998, Neuroscience Research.

Hypotensive effect of bunitrolol at low plasma concentrations in conscious, unrestrained spontaneously hypertensive rats.

K. Kawashima, A. Nagakura, K. Fujimoto, 1985, Japanese journal of pharmacology.

Phorbol ester stimulates acetylcholine synthesis in cultured endothelial cells isolated from porcine cerebral microvessels

I. Morita, S. Murota, K. Kawashima, 1994, Brain Research.

Maintenance of constant blood acetylcholine content before and after feeding in young chimpanzees

K. Kawashima, I. Hayasaka, Y. Mori, 1997, Neuroscience Letters.

Presence of Acetylcholine in the Blood and its Production by Choline Acetyltransferase in Lymphocytes

K. Kawashima, T. Kasahara, H. Misawa, 1997 .

Species differences in the concentration of acetylcholine, a neurotransmitter, in whole blood and plasma

K. Kawashima, T. Fujii, S. Yamada, 1995, Neuroscience Letters.

Effects of Physostigmine and Some Nitric Oxide‐Cyclic GMP‐Related Compounds on Muscarinic Receptor‐Mediated Autoinhibition of Hippocampal Acetylcholine Release

K. Kawashima, K. Fujimoto, Takeshi Suzuki, 1993, Journal of neurochemistry.

Presence of acetylcholine in blood and its localization in circulating mononuclear leukocytes of humans

K. Kawashima, K. Kajiyama, K. Fujimoto, 1993 .

Plasma concentration of acetylcholine in young women

K. Kawashima, K. Fujimoto, Takeshi Suzuki, 1987, Neuroscience Letters.

Expression of Choline Acetyltransferase mRNA and Protein in T-Lymphocytes

K. Kawashima, H. Misawa, T. Fujii, 1995 .

Expression of acetylcholine (ACh) and ACh-synthesizing activity in Archaea.

H. Nishimasu, Y. Kamagata, T. Kanai, 2005, Life sciences.

Evaluation of the pharmacological activity of extracts from amomi semen on the gastrointestinal tracts.

K. Kawashima, Y. Matsushita, T. Yamazaki, 2000, Journal of ethnopharmacology.

Enhancement of hippocampal cholinergic neurotransmission through 5-HT1A receptor-mediated pathways by repeated lithium treatment in rats.

K. Kawashima, T. Fujii, Y. Nakajima, 2000, Canadian journal of physiology and pharmacology.

Ubiquitous expression of acetylcholine and its biological functions in life forms without nervous systems.

T. Imanaka, M. Kamekura, K. Kawashima, 2007, Life sciences.

Regional differences in extracellular choline dependency of acetylcholine synthesis in the rat brain

K. Kawashima, K. Fujimoto, Takeshi Suzuki, 1991, Neuroscience Research.

Melatonin secretion in normal pressure hydrocephalus after cerebral aneurysm rupture--investigation before and after ventriculoperitoneal shunt.

K. Kawashima, T. Masuzawa, H. Iwasa, 1991, Neurologia medico-chirurgica.

Determination of Acetylcholine Release in the Striatum of Anesthetized Rats Using In Vivo Microdialysis and a Radioimmunoassay

T. Hayakawa, K. Kawashima, K. Fujimoto, 1991, Journal of neurochemistry.

ROLE OF NITRIC OXIDE IN THE CONTROL OF BLOOD PRESSURE IN YOUNG AND ADULT SPONTANEOUSLY HYPERTENSIVE RATS

K. Kawashima, H. Amano, T. Fujii, 1995, Clinical and experimental pharmacology & physiology. Supplement.

ANTIHYPERTENSIVE EFFECTS, DETERMINED BY A TELEMETRY METHOD, OF TRICHLOROMETHIAZIDE AND 7–O‐ETHYLFANGCHINOLINE, A DERIVATIVE OF TETRANDRINE, IN SPONTANEOUSLY HYPERTENSIVE RATS

K. Kawashima, H. Amano, T. Fujii, 1995, Clinical and experimental pharmacology & physiology. Supplement.

Antihypertensive effect of synthetic tetrandrine derivatives in SHR rats.

K. Kawashima, T. Hayakawa, K. Fujimoto, 1991, General pharmacology.

Reduction in blood pressure and vascular reactivities to pressor substances by chronic treatment with piretanide in spontaneously hypertensive rats.

T. Hayakawa, K. Kawashima, K. Fujimoto, 1989, General pharmacology.

Antihypertensive and diuretic effects of YM-09730-5, a new calcium antagonist, in stroke-prone spontaneously hypertensive rats.

K. Kawashima, O. Inagaki, K. Fujimoto, 1991, General pharmacology.

Recent progress in revealing the biological and medical significance of the non-neuronal cholinergic system.

W. Kummer, C. Kirkpatrick, K. Kawashima, 2015, International immunopharmacology.

Presynaptic M1 muscarinic receptor modulates spontaneous release of acetylcholine from rat basal forebrain slices

K. Kawashima, K. Fujimoto, Takeshi Suzuki, 1988, Neuroscience Letters.

Antihypertensive effect of repeatedly administered YM358, an angiotensin AT1-receptor antagonist, in stroke-prone spontaneously hypertensive rats.

K. Kawashima, T. Fujii, K. Fujimoto, 1997, Japanese journal of pharmacology.

Effect of repeated administration of KT3-671, a nonpeptide AT1 receptor antagonist, on diurnal variation in blood pressure, heart rate, and locomotor activity in stroke-prone spontaneously hypertensive rats as determined by radiotelemetry.

K. Kawashima, H. Amano, T. Fujii, 1996, Journal of cardiovascular pharmacology.

Some interactions of L-DOPA and its related compounds with glutamate receptors.

Y. Goshima, K. Kawashima, T. Miyamae, 1999, Life sciences.

Synthesis and Biodistribution of N- [(2RS, 3RS)-1-Benzyl-2-Methyl-3-Pyrrolidinyl]-5-Chloro-2-Methoxy-4-[11C]Methylaminobenzamide, [11C]YM-09151-2: A New in Vivo Ligand for Dopamine D2 Receptors

K. Ishiwata, K. Hatano, Y. Kanno, 1986 .

Possible Dynamic Neurotransmitter Metabolism Surrounding the Fetus

K. Kawashima, N. Sakuragawa, M. Elwan, 1999, Journal of child neurology.

Expression of acetylcholine in lymphocytes and modulation of an independent lymphocytic cholinergic activity by immunological stimulation

K. Kawashima, T. Fujii, Yoshihiro Watanabe, 2002 .

Down-regulation of secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related peptide-1 (SLURP-1), an endogenous allosteric alpha7 nicotinic acetylcholine receptor modulator, in murine and human asthmatic conditions.

K. Kawashima, T. Nagase, H. Misawa, 2010, Biochemical and biophysical research communications.

Alteration of FHR pattern and cerebral metabolic rate of glucose of the fetus measured by positron emission tomography during progress of acidemia. The significance of overshoot acceleration in FHR

A. Yajima, K. Okamura, K. Kawashima, 1989, Journal of perinatal medicine.

Effects of the centrally acting cholinesterase inhibitors tetrahydroaminoacridine and E2020 on the basal concentration of extracellular acetylcholine in the hippocampus of freely moving rats

K. Kawashima, T. Fujii, K. Fujimoto, 1994, Naunyn-Schmiedeberg's Archives of Pharmacology.

Localization of Acetylcholine-Related Molecules in the Retina: Implication of the Communication from Photoreceptor to Retinal Pigment Epithelium

Masahiko Watanabe, A. Koizumi, S. Kishi, 2012, PloS one.

[Expression of non-neuronal acetylcholine and its biological roles in mammalian species].

K. Kawashima, 2006, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

Acetylcholine increase in amniotic fluid of experimental rats for intrauterine growth retardation.

T. Horikoshi, K. Kawashima, N. Sakuragawa, 2003, Life sciences.

Plasma renin activity determined by two different methods in spontaneously hypertensive rats.

K. Kawashima, S. Kuriyama, H. Sokabe, 1982, Japanese heart journal.

Phorbol ester enhances choline uptake in cultured porcine brain endothelial cells

I. Morita, S. Murota, K. Kawashima, 1996 .

Endogenous glutamatergic synaptic activity elicits acetylcholine release from rat cultured septal cells

K. Kawashima, Ryoichi Takagi, T. Matsugi, 2003, Neuroscience Research.

Picrotoxin increased acetylcholine release from rat cultured embryonic septal neurons

K. Kawashima, Ryoichi Takagi, Takeshi Suzuki, 2004, Neuroscience Letters.

Nerve growth factor treatment induces high-potassium-evoked calcium-dependent acetylcholine release in cultured embryonic rat septal cells

K. Kawashima, K. Fujimoto, Takeshi Suzuki, 1994, Brain Research.

Acetylcholine synthesis is modulated by acetylcholine content of cytosolic fraction but not by that of releasable fraction

K. Kawashima, K. Fujimoto, Takeshi Suzuki, 1992, Neuroscience Letters.

Hemicholinium-3-resistant choline uptake system linked to acetylcholine synthesis in the rat hippocampus

K. Kawashima, Takeshi Suzuki, Yuko Kashima, 1989, Neuroscience Letters.

Enhancement of the serotonin-mediated acetylcholine release by repeated desmethylimipramine treatment in the hippocampus of freely moving rats.

K. Kawashima, T. Fujii, S. Ohba, 1999, Japanese journal of pharmacology.

Enhancement of cerebral cortical acetylcholine release by intraperitoneal acetic acid and its suppression by analgesics in freely moving rats

K. Kawashima, T. Fujii, Kazuyo Hosonuma, 2000, Neuroscience Letters.

Tacrine increases stimulation-evoked acetylcholine release from rat hippocampal slices.

K. Kawashima, K. Fujimoto, H. Nonaka, 1994, Japanese journal of pharmacology.

Nitric oxide increases stimulation-evoked acetylcholine release from rat hippocampal slices by a cyclic GMP-independent mechanism

K. Kawashima, T. Fujii, K. Fujimoto, 1997, Brain Research.

Does Tacrine Increase Acetylcholine Release from the Hippocampus

K. Kawashima, Takeshi Suzuki, 1995 .

Pharmacokinetics and pharmacodynamics of propranolol stereoisomers in hyperthyroid patients

K. Kawashima, A. Ebihara, H. Ishikawa, 1981, European Journal of Clinical Pharmacology.

Immunological Methods for the Determination of Beta-Blockers

K. Kawashima, 1989 .

Pharmacokinetics of propranolol isomers and their relationships with beta adrenoceptor blocking activity in rabbits administered with dl-propranolol.

K. Kawashima, H. Ishikawa, 1980, Journal of Pharmacology and Experimental Therapeutics.

Metabolism of 45Ti-Labeled Compounds: Effect of Ascorbic Acid

K. Ishiwata, T. Ido, K. Kawashima, 1985 .

Glucocorticoid treatment increases inhibitory m(2) muscarinic receptor expression and function in the airways.

A. Fryer, D. Jacoby, K. Kawashima, 2001, American journal of respiratory cell and molecular biology.

GTS-21 Enhances Regulatory T Cell Development from T Cell Receptor-Activated Human CD4+ T Cells Exhibiting Varied Levels of CHRNA7 and CHRFAM7A Expression

K. Kawashima, T. Kasahara, S. Ono, 2023, International journal of molecular sciences.

Reconciling neuronally and nonneuronally derived acetylcholine in the regulation of immune function

K. Kawashima, H. Misawa, Y. Moriwaki, 2012, Annals of the New York Academy of Sciences.

Placental Transfer of Positron-emitting Metabolic Substrates

K. Ishiwata, R. Iwata, H. Yamada, 1983 .

CRAC channels are required for [Ca(2+)]i oscillations and c-fos gene expression after muscarinic acetylcholine receptor activation in leukemic T cells.

K. Kawashima, Masato Mashimo, T. Fujii, 2016, Life sciences.

Antihypertensive effect of chronic KT3-671, a structurally new nonpeptide angiotensin AT1-receptor antagonist, in stroke-prone spontaneously hypertensive rats.

K. Kawashima, H. Amano, T. Fujii, 1995, Japanese journal of pharmacology.

Regulatory mechanisms of acetylcholine synthesis and release by T cells.

K. Kawashima, T. Fujii, Yuki Takada‐Takatori, 2012, Life sciences.

Contributions of Non-Neuronal Cholinergic Systems to the Regulation of Immune Cell Function, Highlighting the Role of α7 Nicotinic Acetylcholine Receptors

K. Kawashima, Atsuo Nomura, Masato Mashimo, 2024, International journal of molecular sciences.