Jiesheng Kang

发表

Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches.

Roy J. Vaz, M. Preobrazhenskaya, R. Pearlstein, 2003, Bioorganic & medicinal chemistry letters.

A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs.

Jiesheng Kang, Xiao-Liang Chen, D. Rampe, 2002, European journal of pharmacology.

Proarrhythmic mechanisms of the common anti-diarrheal medication loperamide: revelations from the opioid abuse epidemic

Roy J. Vaz, D. R. Compton, Jiesheng Kang, 2016, Naunyn-Schmiedeberg's Archives of Pharmacology.

A β-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity.

Xin Chen, Qingping Wang, Jiesheng Kang, 2012, Bioorganic & medicinal chemistry letters.

Predictive models for hERG potassium channel blockers.

Gabriele Cruciani, Roy J Vaz, Arnaldo Fravolini, 2005, Bioorganic & medicinal chemistry letters.

Cardiac Ion Channel Effects of Tolterodine

Jiesheng Kang, Xiao-Liang Chen, James Hendrix, 2004, Journal of Pharmacology and Experimental Therapeutics.

FUNCTIONAL INTERACTION BETWEEN DPI 201‐106, A DRUG THAT MIMICS CONGENITAL LONG QT SYNDROME, AND SEVOFLURANE ON THE GUINEA‐PIG CARDIAC ACTION POTENTIAL

Jiesheng Kang, Xiao-Liang Chen, D. Rampe, 2007, Clinical and experimental pharmacology & physiology.

Electrophysiological Responses of Olfactory Receptor and Bulb Neurons to Stimulus Mixtures and to Their Individual Components in the Channel Catfish, Ictalurus Punctatus.

Jiesheng Kang, 1994 .

In vitro Testing of Proarrhythmic Toxicity

Jiesheng Kang, Haoyu Zeng, 2012 .

Design of bivalent ligands using hydrogen bond linkers: synthesis and evaluation of inhibitors for human β-tryptase

Roy J. Vaz, Xin Chen, F. Liu, 2004 .

Pentamidine-Induced Long QT Syndrome and Block of hERG Trafficking

Y. Kuryshev, A. Brown, B. Wible, 2005, Journal of Pharmacology and Experimental Therapeutics.

Observations on conducting whole‐cell patch clamping of the hERG cardiac K+ channel in pure human serum

Jiesheng Kang, D. Rampe, M. Searles, 2017, Journal of applied toxicology : JAT.

Mechanisms Underlying the QT Interval–prolonging Effects of Sevoflurane and Its Interactions with Other QT-prolonging Drugs

Jiesheng Kang, D. Rampe, Hongge Wang, 2006, Anesthesiology.

Development and Evaluation of High Throughput Functional Assay Methods for hERG Potassium Channel

T. Garyantes, Jiesheng Kang, D. Rampe, 2001, Journal of biomolecular screening.

In Vitro Electrocardiographic and Cardiac Ion Channel Effects of (−)-Epigallocatechin-3-Gallate, the Main Catechin of Green Tea

Jiesheng Kang, D. Rampe, J. Ji, 2010, Journal of Pharmacology and Experimental Therapeutics.

Discovery of a Small Molecule Activator of the Human Ether-a-go-go-Related Gene (HERG) Cardiac K+ Channel

Jiesheng Kang, D. Rampe, M. Tabart, 2005, Molecular Pharmacology.

Proarrhythmic mechanisms of the common anti-diarrheal medication loperamide: revelations from the opioid abuse epidemic

Roy J. Vaz, D. R. Compton, Jiesheng Kang, 2016, Naunyn-Schmiedeberg's Archives of Pharmacology.

Interactions of the narcotic l-α-acetylmethadol with human cardiac K+ channels

Jiesheng Kang, D. Rampe, Hongge Wang, 2003 .

Molecular determinants of loperamide and N-desmethyl loperamide binding in the hERG cardiac K+ channel.

Roy J Vaz, Roy J. Vaz, Jiesheng Kang, 2017, Bioorganic & medicinal chemistry letters.

Interactions of the narcotic l-alpha-acetylmethadol with human cardiac K+ channels.

Jiesheng Kang, D. Rampe, Hongge Wang, 2003, European journal of pharmacology.

Molecular Interaction Fields in ADME and Safety

Yi Li, Meng Zhang, Roy J. Vaz, 2006 .

Mephedrone, a new designer drug of abuse, produces acute hemodynamic effects in the rat.

Jiesheng Kang, D. Rampe, Xiaoyou Ying, 2012, Toxicology letters.

Ca2+ Channel Activators Reveal Differential L-Type Ca2+ Channel Pharmacology between Native and Stem Cell-Derived Cardiomyocytes

Jiesheng Kang, D. Rampe, Q. Lei, 2012, Journal of Pharmacology and Experimental Therapeutics.

Channel Activators Reveal Differential L-Type Ca Channel Pharmacology between Native and Stem Cell-Derived Cardiomyocytes

Jiesheng Kang, D. Rampe, Q. Lei, 2012 .

Interactions of the antimalarial drug mefloquine with the human cardiac potassium channels KvLQT1/minK and HERG.

Jiesheng Kang, D. Rampe, D Rampe, 2001, The Journal of pharmacology and experimental therapeutics.

The antipsychotic drugs sertindole and pimozide block erg3, a human brain K(+) channel.

Jiesheng Kang, D. Rampe, J. Kang, 2001, Biochemical and biophysical research communications.

Interactions of a series of fluoroquinolone antibacterial drugs with the human cardiac K+ channel HERG.

D J Triggle, D. Triggle, Jiesheng Kang, 2001, Molecular pharmacology.