Hui-Sun Lee

发表

A novel hypothesis for the binding mode of HERG channel blockers.

C. Leem, H. Choe, K. H. Nah, 2006, Biochemical and biophysical research communications.

Identification of (beta-carboxyethyl)-rhodanine derivatives exhibiting peroxisome proliferator-activated receptor gamma activity.

Sukjoon Yoon, Jiwon Choi, Hui-Sun Lee, 2010, European journal of medicinal chemistry.

Effects of N-glycosylation on protein conformation and dynamics: Protein Data Bank analysis and molecular dynamics simulation study

Wonpil Im, Yifei Qi, W. Im, 2015, Scientific Reports.

Effects of N-Glycan Composition on Structure and Dynamics of IgG1 Fc and Their Implications for Antibody Engineering

Wonpil Im, W. Im, Hui-Sun Lee, 2017, Scientific Reports.

Lipid-linked oligosaccharides in membranes sample conformations that facilitate binding to oligosaccharyltransferase.

Alexander D. MacKerell, Jeffery B. Klauda, Nathan R Kern, 2014, Biophysical journal.

Improving Virtual Screening Performance against Conformational Variations of Receptors by Shape Matching with Ligand Binding Pocket

Hui Sun Lee, Cheol Soon Lee, Jeong Sook Kim, 2009, J. Chem. Inf. Model..

Restricted N-glycan Conformational Space in the PDB and Its Implication in Glycan Structure Modeling

Sunhwan Jo, Jeffrey Skolnick, Hui Sun Lee, 2013, PLoS Comput. Biol..

Monastrol, a selective inhibitor of the mitotic kinesin Eg5, induces a distinctive growth profile of dendrites and axons in primary cortical neuron cultures.

J. Huh, Seung-Yong Yoon, Donghou Kim, 2005, Cell motility and the cytoskeleton.

Universal and mutation-resistant anti-enteroviral activity: potency of small interfering RNA complementary to the conserved cis-acting replication element within the enterovirus coding region.

E. Jeon, Heuiran Lee, Jeonghyun Ahn, 2007, The Journal of general virology.

A novel program to design siRNAs simultaneously effective to highly variable virus genomes.

Heuiran Lee, E. Jun, Jeonghyun Ahn, 2009, Biochemical and biophysical research communications.

Potential Application of Alchemical Free Energy Simulations to Discriminate GPCR Ligand Efficacy.

Chaok Seok, W. Im, Hui-Sun Lee, 2015, Journal of chemical theory and computation.

Expression, High Cell Density Culture and Purification of Recombinant EC-SOD in Escherichia coli

H. Choe, Hui-Sun Lee, Young-Jin Son, 2010, Applied biochemistry and biotechnology.

zVLL-CHO at low concentrations acts as a calpain inhibitor to protect neurons against okadaic acid-induced neurodegeneration

Dong-Hou Kim, Seung-Yong Yoon, H. Choe, 2012, Neuroscience Letters.

Quantitative Analysis of Viral RNA in the Murine Heart and Pancreas with Different Concentration of Coxsackievirus B3

Moo-Song Lee, Heuiran Lee, E. Jun, 2006, Intervirology.

CHARMM-GUI Glycan Modeler for modeling and simulation of carbohydrates and glycoconjugates

Sunhwan Jo, Jooyoung Lee, Jumin Lee, 2019, Glycobiology.

H(1) antihistamine drug promethazine directly blocks hERG K(+) channel.

H. Choe, Hui-Sun Lee, S. Jo, 2009, Pharmacological research.

Papaverine, A Vasodilator, Blocks The Pore Of The Herg Channel At Submicromolar Concentration

S. Moh, H. Choe, Hui-Sun Lee, 2009 .

Application of Binding Free Energy Calculations to Prediction of Binding Modes and Affinities of MDM2 and MDMX Inhibitors

Sunhwan Jo, Hui Sun Lee, Wonpil Im, 2012, J. Chem. Inf. Model..

CHARMM‐GUI ligand reader and modeler for CHARMM force field generation of small molecules

Charles L. Brooks, Sunhwan Jo, Jumin Lee, 2017, J. Comput. Chem..

CHARMM-GUI PDB manipulator for advanced modeling and simulations of proteins containing nonstandard residues.

Alexander D. MacKerell, Sunhwan Jo, Benoît Roux, 2014, Advances in protein chemistry and structural biology.

1,3-Diphenyl-1H-pyrazole derivatives as a new series of potent PPARγ partial agonists.

Sukjoon Yoon, Jiwon Choi, Hui-Sun Lee, 2010, Bioorganic & medicinal chemistry.

CHARMM-GUI Ligand Binder for Absolute Binding Free Energy Calculations and Its Application

Wei Jiang, Sunhwan Jo, Hui Sun Lee, 2013, J. Chem. Inf. Model..

Glycan Reader is improved to recognize most sugar types and chemical modifications in the Protein Data Bank

Sunhwan Jo, Jumin Lee, Hui Sun Lee, 2017, Bioinform..

L-Met Activates Arabidopsis GLR Ca2+ Channels Upstream of ROS Production and Regulates Stomatal Movement.

Z. Pei, W. Im, Juan Wang, 2016, Cell reports.

Transposon-directed base-exchange mutagenesis (TDEM): a novel method for multiple-nucleotide substitutions within a target gene.

S. Morrison, Sukjoon Yoon, Hui-Sun Lee, 2009, BioTechniques.

Augmenting the antinociceptive effects of nicotinic acetylcholine receptor activity through lynx1 modulation

W. Im, Hui-Sun Lee, Huaixing Wang, 2018, PloS one.

Identification of Ligand Templates using Local Structure Alignment for Structure-Based Drug Design

Hui Sun Lee, Wonpil Im, W. Im, 2012, J. Chem. Inf. Model..

Maintained activity of glycogen synthase kinase-3beta despite of its phosphorylation at serine-9 in okadaic acid-induced neurodegenerative model.

Seung-Yong Yoon, H. Choe, Hui-Sun Lee, 2010, Biochemical and biophysical research communications.

Optimization of High Throughput Virtual Screening by Combining Shape‐Matching and Docking Methods.

Ruben Abagyan, Irina Kufareva, Sukjoon Yoon, 2008 .

Computational analysis of the quaternary structural changes induced by point mutations in human UDP-glucose dehydrogenase.

C. Leem, H. Choe, Hui-Sun Lee, 2009, Archives of biochemistry and biophysics.

GS-align for glycan structure alignment and similarity measurement

Sunhwan Jo, Jooyoung Lee, Jeffrey Skolnick, 2015, Bioinform..

Structural Basis of Cooperativity in Human UDP-Glucose Dehydrogenase

R. Robinson, J. Huh, L. Kang, 2011, PloS one.

Ligand Binding Site Detection by Local Structure Alignment and Its Performance Complementarity

Hui Sun Lee, Wonpil Im, W. Im, 2013, J. Chem. Inf. Model..

CHARMM-GUI Micelle Builder for Pure/Mixed Micelle and Protein/Micelle Complex Systems

Sunhwan Jo, Hui Sun Lee, Wonpil Im, 2013, J. Chem. Inf. Model..

CHARMM‐GUI 10 years for biomolecular modeling and simulation

Alexander D. MacKerell, Xi Cheng, Sunhwan Jo, 2017, J. Comput. Chem..

G-LoSA for Prediction of Protein-Ligand Binding Sites and Structures.

Wonpil Im, W. Im, Hui-Sun Lee, 2017, Methods in molecular biology.

BSP‐SLIM: A blind low‐resolution ligand‐protein docking approach using predicted protein structures

Yang Zhang, Yang Zhang, Hui-Sun Lee, 2012, Proteins.

Potentiation of anti-angiogenic activity of heparin by blocking the ATIII-interacting pentasaccharide unit and increasing net anionic charge.

Beom Suk Lee, Seung Woo Chung, Y. Byun, 2012, Biomaterials.

Effects of N-Glycan Composition on Structure and Dynamics of IgG1 Fc and Their Implications for Antibody Engineering

W. Im, Hui-Sun Lee, 2017, Scientific Reports.

Ligand-Binding Site Structure Refinement Using Molecular Dynamics with Restraints Derived from Predicted Binding Site Templates.

W. Im, Hui-Sun Lee, H. Guterres, 2019, Journal of chemical theory and computation.

A role for Leu247 residue within transmembrane domain 2 in ginsenoside-mediated α7 nicotinic acetylcholine receptor regulation

Byung-Hwan Lee, Sun-Hye Choi, S. Hwang, 2009, Molecules and cells.

Optimization of High Throughput Virtual Screening by Combining Shape-Matching and Docking Methods

Jiwon Choi, Ruben Abagyan, Irina Kufareva, 2008, J. Chem. Inf. Model..

QHELIX: A Computational Tool for the Improved Measurement of Inter-Helical Angles in Proteins

Sukjoon Yoon, Jiwon Choi, Hui-Sun Lee, 2007, The protein journal.

Transmembrane motions of PglB induced by LLO are coupled with EL5 loop conformational changes necessary for OST activity

W. Im, Hui-Sun Lee, 2017, Glycobiology.

Stalis: A Computational Method for Template‐Based Ab Initio Ligand Design

Wonpil Im, Hui Sun Lee, W. Im, 2019, J. Comput. Chem..

Papaverine, a Vasodilator, Blocks the Pore of the HERG Channel at Submicromolar Concentration

S. Moh, H. Choe, Hui-Sun Lee, 2008, Journal of cardiovascular pharmacology.

Improving Virtual Screening Performance against Conformational Variations of Receptors by Shape Matching with Ligand Binding Pocket

H. Choe, Hui-Sun Lee, C. Lee, 2009, J. Chem. Inf. Model..