Christoph Hasenhindl

发表

Molecular Dynamics Simulation of the Crystallizable Fragment of IgG1—Insights for the Design of Fcabs

C. Obinger, C. Oostenbrink, Balder Lai, 2014, International journal of molecular sciences.

Engineered IgG1‐Fc – one fragment to bind them all

Christian Obinger, Elisabeth Lobner, Michael W. Traxlmayr, 2016, Immunological reviews.

Creating stable stem regions for loop elongation in Fcabs — Insights from combining yeast surface display, in silico loop reconstruction and molecular dynamics simulations

C. Obinger, C. Oostenbrink, L. Serrano, 2014, Biochimica et biophysica acta.

Differences in usability of rabbit IgG and chicken IgY after clean-up and impact on gold labelling properties.

Christoph Hasenhindl, M. Führer, S. Baumgartner, 2009, Journal of immunological methods.

Effectiveness of natural and synthetic blocking reagents and their application for detecting food allergens in enzyme-linked immunosorbent assays

Christoph Hasenhindl, M. Führer, S. Baumgartner, 2009, Analytical and bioanalytical chemistry.

Design of a colicin E7 based chimeric zinc-finger nuclease

Gábor Nagy, Chris Oostenbrink, Eszter Németh, 2014, Journal of Computer-Aided Molecular Design.

Directed evolution of Her2/neu-binding IgG1-Fc for improved stability and resistance to aggregation by using yeast surface display.

C. Obinger, F. Rüker, Christoph Hasenhindl, 2013, Protein engineering, design & selection : PEDS.

Stability assessment on a library scale: a rapid method for the evaluation of the commutability and insertion of residues in C-terminal loops of the CH3 domains of IgG1-Fc

C. Obinger, F. Rüker, Christoph Hasenhindl, 2013, Protein engineering, design & selection : PEDS.

Construction of a Stability Landscape of the CH3 Domain of Human IgG1 by Combining Directed Evolution with High Throughput Sequencing

C. Obinger, N. Borth, F. Rüker, 2012, Journal of molecular biology.

Construction of pH-sensitive Her2-binding IgG1-Fc by directed evolution

C. Obinger, C. Oostenbrink, F. Rüker, 2014, Biotechnology journal.

Fcab-HER2 Interaction: a Ménage à Trois. Lessons from X-Ray and Solution Studies.

C. Obinger, K. Djinović-Carugo, Martin Puchinger, 2017, Structure.

Directed evolution of stabilized IgG1-Fc scaffolds by application of strong heat shock to libraries displayed on yeast

C. Obinger, F. Rüker, Christoph Hasenhindl, 2012, Biochimica et biophysica acta.