P. Petronini

F. Ciardiello, G. Troncone, T. Troiani, 2018, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Combination of EGFR-TKIs and chemotherapy in advanced EGFR mutated NSCLC: Review of the literature and future perspectives.

M. Tiseo, P. Petronini, R. Alfieri, 2019, Critical reviews in oncology/hematology.

Differential adaptive response to hyperosmolarity of 3T3 and transformed SV3T3 cells.

G. Piedimonte, L. Silvotti, A. Mazzini, 1991, Experimental cell research.

Hyperosmolarity-induced stress proteins in chick embryo fibroblasts.

G. Piedimonte, L. Silvotti, A. Mazzini, 1987, Experimental cell research.

Acquired BRAF G469A Mutation as a Resistance Mechanism to First-Line Osimertinib Treatment in NSCLC Cell Lines Harboring an EGFR Exon 19 Deletion

M. Tiseo, F. Riccardi, P. Petronini, 2019, Targeted Oncology.

YES1 and MYC Amplifications as Synergistic Resistance Mechanisms to Different Generation ALK Tyrosine Kinase Inhibitors in Advanced NSCLC: Brief Report of Clinical and Preclinical Proofs

M. Tiseo, V. De Sanctis, R. Bertorelli, 2022, JTO clinical and research reports.

Combined hyaluronate‐based films loaded with pemetrexed and cisplatin for the treatment of malignant pleural mesothelioma: Preliminary evaluation in an orthotopic tumor recurrence model

P. Colombo, F. Sonvico, P. Carbognani, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Activation of heat-shock transcription factor 1 by hypertonic shock in 3T3 cells.

P. Petronini, R. Alfieri, S. Urbani, 1996, The Biochemical journal.

Shiga toxin 1 and ricin inhibit the repair of H2O2-induced DNA single strand breaks in cultured mammalian cells.

L. Barbieri, F. Stirpe, P. Sestili, 2005, DNA repair.

Hyperosmotic stress response: comparison with other cellular stresses

P. Petronini, R. Alfieri, 2007, Pflügers Archiv - European Journal of Physiology.

Expression of Human CD44v6 in Non-Small-Cell Lung Cancer

P. Solli, L. Spaggiari, P. Carbognani, 1998, European Surgical Research.

An effective solution for prolonged preservation of cultured human pulmonary artery endothelial cells.

P. Solli, L. Spaggiari, P. Carbognani, 1996, Transplantation.

Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells 1

L. Barbieri, F. Stirpe, P. Sestili, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

International expert consensus on primary systemic therapy in the management of early breast cancer: highlights of the Fourth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2010).

L. V. van't Veer, S. Fox, C. Sotiriou, 2011, Journal of the National Cancer Institute. Monographs.

Pre-treatment with the CDK4/6 inhibitor palbociclib improves the efficacy of paclitaxel in TNBC cells

D. Generali, P. Petronini, R. Alfieri, 2019, Scientific Reports.

TRAIL‐induced apoptosis of FHIT‐negative lung cancer cells is inhibited by FHIT re‐expression

M. Vitale, P. Mirandola, P. Petronini, 2009, Journal of cellular physiology.

Dose-dependent effect of FHIT-inducible expression in Calu-1 lung cancer cell line

G. Sozzi, F. Andriani, L. Roz, 2004, Oncogene.

The effect of dextran for hypothermic (10 degrees C) preservation of human fetal lung fibroblasts.

L. Spaggiari, A. Bobbio, P. Carbognani, 1998, The Journal of cardiovascular surgery.

Methodology for the assessment of lung protection. Human pulmonary artery endothelial cell preservation using haemaccel.

P. Solli, L. Spaggiari, P. Carbognani, 1995, Transplantation.

Density-dependent regulation of amino acid transport in a Burkitt lymphoma cell line.

G. Piedimonte, L. Silvotti, P. Petronini, 1989, Cancer letters.

Inhibition of PI 3 K Pathway Reduces Invasiveness and Epithelial-to-Mesenchymal Transition in Squamous Lung Cancer Cell Lines Harboring PIK 3 CA Gene Alterations

A. Ardizzoni, M. Tiseo, C. Lagrasta, 2015 .

Combination of letrozole, metronomic cyclophosphamide and sorafenib is well-tolerated and shows activity in patients with primary breast cancer

S. Fox, A. Harris, K. Gatter, 2014, British Journal of Cancer.

Effect of inducible FHIT and p53 expression in the Calu-1 lung cancer cell line.

G. Sozzi, F. Andriani, L. Roz, 2007, Cancer letters.

Fingerprint Change: Not Visible, But Tangible

L. Garofano, P. Petronini, F. Negri, 2017, Journal of forensic sciences.

Endothelial damage induced by Shiga toxins delivered by neutrophils during transmigration

A. Caprioli, P. Tazzari, F. Ricci, 2010, Journal of leukocyte biology.

Molecular Damage and Induction of Proinflammatory Cytokines in Human Endothelial Cells Exposed to Shiga Toxin 1, Shiga Toxin 2, and α-Sarcin

P. Sestili, P. Petronini, R. Alfieri, 2007, Infection and Immunity.

Synthesis and biological evaluation of tetracyclic fluoroquinolones as antibacterial and anticancer agents.

Jalal A. Zahra, M. El-abadelah, P. Petronini, 2010, Bioorganic & medicinal chemistry.

Shiga Toxin 1, as DNA Repair Inhibitor, Synergistically Potentiates the Activity of the Anticancer Drug, Mafosfamide, on Raji Cells

P. Tazzari, F. Ricci, P. Pagliaro, 2013, Toxins.

Control of protein synthesis by extracellular Na+ in cultured fibroblasts

A. Mazzini, P. Petronini, J. Kay, 1989, Journal of cellular physiology.

Induction of BGT-1 and amino acid system A transport activities in endothelial cells exposed to hyperosmolarity.

P. Petronini, R. Alfieri, M. Bonelli, 2000, American journal of physiology. Regulatory, integrative and comparative physiology.

Induction of betaine‐γ‐aminobutyric acid transport activity in porcine chondrocytes exposed to hypertonicity

E. Angelis, P. Petronini, P. Borghetti, 1999, The Journal of physiology.

Enhancement of the anti-tumor activity of FGFR1 inhibition in squamous cell lung cancer by targeting downstream signaling involved in glucose metabolism

A. Ardizzoni, M. Tiseo, P. Petronini, 2017, Oncotarget.

Cell susceptibility to apoptosis by glutamine deprivation and rescue: Survival and apoptotic death in cultured lymphoma‐leukemia cell lines

G. Guidotti, P. Petronini, R. Alfieri, 1996, Journal of cellular physiology.

Decreased Expression of Heat Shock Protein 70 mRNA and Protein in WI‐38 Human Fibroblasts Aging in Vitro

P. Petronini, R. Alfieri, A. Borghetti, 1992, Annals of the New York Academy of Sciences.

Osmotically inducible uptake of betaine via amino acid transport system A in SV-3T3 cells.

P. Petronini, A. Borghetti, E. De Angelis, 1994, The Biochemical journal.

Cap-independent protein synthesis is enhanced by betaine under hypertonic conditions.

L. Montanaro, P. Petronini, R. Alfieri, 2017, Biochemical and biophysical research communications.

5'-Untranslated region of heat shock protein 70 mRNA drives translation under hypertonic conditions.

L. Montanaro, P. Petronini, R. Alfieri, 2013, Biochemical and biophysical research communications.

Compatible osmolytes modulate the response of porcine endothelial cells to hypertonicity and protect them from apoptosis

P. Petronini, R. Alfieri, M. Bonelli, 2002, The Journal of physiology.

Osmotic regulation of ATA2 mRNA expression and amino acid transport System A activity.

P. Petronini, R. Alfieri, M. Bonelli, 2001, Biochemical and biophysical research communications.

Osmoregulation of amino acid transport activity in cultured fibroblasts.

P. Petronini, A. Severini, A. Borghetti, 1984, Experimental cell research.

The effect of heat shock on amino acid transport and cell volume in 3T3 cells

P. Petronini, R. Alfieri, M. Bonelli, 2001, Amino Acids.

Interaction between occupational radon exposure and tobacco smoke: a systematic review

M. Corradi, P. Petronini, M. Galetti, 2022, Expert review of respiratory medicine.

Adaptive cellular response to osmotic stress in pig articular chondrocytes.

N. Maraldi, M. Maltarello, P. Petronini, 1995, Tissue & cell.

Efficacy of the CDK4/6 Dual Inhibitor Abemaciclib in EGFR-Mutated NSCLC Cell Lines with Different Resistance Mechanisms to Osimertinib

M. Tiseo, Francesco Volta, Maicol Mancini, 2020, Cancers.

Inhibition by suramin of protein synthesis in vitro. Ribosomes as the target of the drug.

P. Petronini, R. Alfieri, M. Brigotti, 2006, Biochimie.

Isolation of circulating lung tumour cells using a non-EpCAM-based capture method

A. Ardizzoni, M. Tiseo, P. Mirandola, 2012, La Rivista Italiana della Medicina di Laboratorio - Italian Journal of Laboratory Medicine.

5-Benzylidene-hydantoins: synthesis and antiproliferative activity on A549 lung cancer cell line.

M. Mor, C. Carmi, P. Petronini, 2009, European journal of medicinal chemistry.

Dual mechanisms of action of the 5-benzylidene-hydantoin UPR1024 on lung cancer cell lines

R. Frazzi, M. Mor, C. Carmi, 2008, Molecular Cancer Therapeutics.

5-benzylidene-hydantoins as new EGFR inhibitors with antiproliferative activity.

M. Mor, C. Carmi, P. Petronini, 2006, Bioorganic & medicinal chemistry letters.

Irreversible inhibition of epidermal growth factor receptor activity by 3-aminopropanamides.

A. Ardizzoni, M. Mor, G. Costantino, 2012, Journal of medicinal chemistry.

Modulation by betaine of cellular responses to osmotic stress.

P. Petronini, P. Borghetti, A. Borghetti, 1992, The Biochemical journal.

Effect of betaine on HSP70 expression and cell survival during adaptation to osmotic stress.

P. Petronini, A. Borghetti, E. De Angelis, 1993, The Biochemical journal.

Epidermal growth factor receptor irreversible inhibitors: chemical exploration of the cysteine-trap portion.

A. Ardizzoni, M. Mor, C. Carmi, 2011, Mini reviews in medicinal chemistry.

Soluble PD-L1 and Circulating CD8+PD-1+ and NK Cells Enclose a Prognostic and Predictive Immune Effector Score in Immunotherapy Treated NSCLC patients.

M. Tiseo, S. Buti, A. Leonetti, 2020, Lung cancer.

Multicomponent analysis of amino acid transport System L in normal and virus-transformed fibroblasts.

S. Gandolfi, P. Petronini, J. Maier, 1987, Biochimica et biophysica acta.

CDK4/6 inhibitors in HER2-positive breast cancer.

D. Generali, L. Zanotti, M. Cappelletti, 2017, Critical reviews in oncology/hematology.

CDK4/6 Inhibition Enhances the Efficacy of Standard Chemotherapy Treatment in Malignant Pleural Mesothelioma Cells

M. Corradi, M. Tiseo, P. Petronini, 2022, Cancers.

The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells

D. Generali, P. Petronini, R. Alfieri, 2018, Journal of experimental & clinical cancer research : CR.

Third generation EGFR inhibitor osimertinib combined with pemetrexed or cisplatin exerts long-lasting anti-tumor effect in EGFR-mutated pre-clinical models of NSCLC

M. Tiseo, A. Romanel, C. Lagrasta, 2019, Journal of experimental & clinical cancer research : CR.

Impairing energy metabolism in solid tumors through agents targeting oncogenic signaling pathways

P. Petronini, R. Alfieri, C. Fumarola, 2018, Biochemical pharmacology.

Combined Inhibition of CDK4/6 and PI3K/AKT/mTOR Pathways Induces a Synergistic Anti-Tumor Effect in Malignant Pleural Mesothelioma Cells

M. Tiseo, D. Calistri, A. Delmonte, 2017, Neoplasia.

Epidermal growth factor receptor tyrosine kinase inhibitors: current status and future perspectives in the development of novel irreversible inhibitors for the treatment of mutant non-small cell lung cancer.

E. Giovannetti, G. Peters, A. Ardizzoni, 2012, Current pharmaceutical design.

Everolimus restores gefitinib sensitivity in resistant non-small cell lung cancer cell lines.

M. Capelletti, A. Ardizzoni, M. Tiseo, 2009, Biochemical pharmacology.

FGFR as potential target in the treatment of squamous non small cell lung cancer.

A. Ardizzoni, M. Tiseo, P. Petronini, 2015, Cancer treatment reviews.

CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells

G. Missale, Francesco Volta, P. Petronini, 2022, Frontiers in Oncology.

Simultaneous Combination of the CDK4/6 Inhibitor Palbociclib With Regorafenib Induces Enhanced Anti-tumor Effects in Hepatocarcinoma Cell Lines

G. Missale, P. Petronini, R. Alfieri, 2020, Frontiers in Oncology.

The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells

D. Generali, P. Petronini, R. Alfieri, 2018, Journal of Experimental & Clinical Cancer Research.

Gefitinib Inhibits Invasive Phenotype and Epithelial-Mesenchymal Transition in Drug-Resistant NSCLC Cells with MET Amplification

E. Giovannetti, A. Ardizzoni, M. Tiseo, 2013, PloS one.

Novel irreversible epidermal growth factor receptor inhibitors by chemical modulation of the cysteine-trap portion.

A. Ardizzoni, M. Mor, C. Carmi, 2010, Journal of medicinal chemistry.

Combination of Gefitinib and Pemetrexed Prevents the Acquisition of TKI Resistance in NSCLC Cell Lines Carrying EGFR‐Activating Mutation

A. Ardizzoni, M. Tiseo, C. Lagrasta, 2016, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Combined use of anti-ErbB monoclonal antibodies and erlotinib enhances antibody-dependent cellular cytotoxicity of wild-type erlotinib-sensitive NSCLC cell lines

A. Ardizzoni, M. Tiseo, A. Mutti, 2012, Molecular Cancer.

Epidermal Growth Factor Receptor Intron-1 Polymorphism Predicts Gefitinib Outcome in Advanced Non-small Cell Lung Cancer

M. Capelletti, A. Ardizzoni, L. Boni, 2008, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Trastuzumab emtansine is active on HER-2 overexpressing NSCLC cell lines and overcomes gefitinib resistance

A. Ardizzoni, M. Tiseo, C. Lagrasta, 2014, Molecular Cancer.

Predictive and prognostic value of early response assessment using 18FDG-PET in advanced non-small cell lung cancer patients treated with erlotinib

P. Bruzzi, A. Ardizzoni, M. Tiseo, 2014, Cancer Chemotherapy and Pharmacology.

Effect of ABCG2/BCRP Expression on Efflux and Uptake of Gefitinib in NSCLC Cell Lines

A. Ardizzoni, M. Tiseo, A. Mutti, 2015, PloS one.

Molecular mechanisms underlying the antitumor activity of 3-aminopropanamide irreversible inhibitors of the epidermal growth factor receptor in non-small cell lung cancer.

E. Giovannetti, G. Peters, A. Ardizzoni, 2013, Neoplasia.

Effect of hyperosmolarity on the activity of amino acid transport system L in avian fibroblasts

P. Petronini, A. Borghetti, M. Tramacere, 1984, Journal of cellular physiology.

Tumor-infiltrating lymphocytes and breast cancer: Beyond the prognostic and predictive utility

D. Generali, L. Zanotti, A. Bottini, 2017, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.

Proteasome inhibition increases HuR level, restores heat-inducible HSP72 expression and thermotolerance in WI-38 senescent human fibroblasts

P. Petronini, R. Alfieri, M. Bonelli, 2004, Experimental Gerontology.

Heat-induced proteasomic degradation of HSF1 in serum-starved human fibroblasts aging in vitro.

P. Petronini, R. Alfieri, M. Poli, 2001, Experimental cell research.

Attenuated expression of 70-kDa heat shock protein in WI-38 human fibroblasts during aging in vitro.

P. Petronini, R. Alfieri, M. Bonelli, 1999, Experimental cell research.

Effect of an alkaline shift on induction of the heat shock response in human fibroblasts

P. Petronini, R. Alfieri, A. Borghetti, 1995, Journal of cellular physiology.

Enhancement of the anti-tumor activity of FGFR1 inhibition in squamous cell lung cancer by targeting downstream signaling involved in glucose metabolism.

A. Ardizzoni, M. Tiseo, P. Petronini, 2017, Oncotarget.

Protease activation during HIV infection in a CD4-positive cell line.

L. Montagnier, V. Favier, G. Piedimonte, 1990, AIDS research and human retroviruses.

Comparison between 3‐MCPD and its palmitic esters in a 90‐day toxicological study

A. Mutti, P. Petronini, E. Barocelli, 2011 .

Trastuzumab emtansine delays and overcomes resistance to the third-generation EGFR-TKI osimertinib in NSCLC EGFR mutated cell lines

M. Tiseo, N. Naldi, P. Petronini, 2017, Journal of experimental & clinical cancer research : CR.

The Effect of Verapamil and Diltiazem on Alveolar Type II Cells during Warm and Cold Metabolic Ischaemia

L. Spaggiari, P. Carbognani, M. Rusca, 1994, The Journal of international medical research.

Inhibition of PI3K Pathway Reduces Invasiveness and Epithelial-to-Mesenchymal Transition in Squamous Lung Cancer Cell Lines Harboring PIK3CA Gene Alterations

A. Ardizzoni, M. Tiseo, C. Lagrasta, 2015, Molecular Cancer Therapeutics.

Interaction between Occupational and Non-Occupational Arsenic Exposure and Tobacco Smoke on Lung Cancerogenesis: A Systematic Review

M. Corradi, P. Petronini, P. Mozzoni, 2023, International journal of environmental research and public health.

Drug-induced cellular death dynamics monitored by a highly sensitive organic electrochemical system.

S. Iannotta, G. Tarabella, A. Romeo, 2015, Biosensors & bioelectronics.

Different HSP70 expression and cell survival during adaptive responses of 3T3 and transformed 3T3 cells to osmotic stress.

P. Petronini, R. Alfieri, A. Borghetti, 1993, British Journal of Cancer.

Effects of sorafenib on energy metabolism in breast cancer cells: role of AMPK–mTORC1 signaling

D. Generali, P. Petronini, R. Alfieri, 2013, Breast Cancer Research and Treatment.

Afatinib therapy in case of EGFR G724S emergence as resistance mechanism to osimertinib

M. Tiseo, A. Leonetti, C. Lagrasta, 2021, Anti-cancer drugs.

Concurrent Acquired BRAF V600E Mutation and MET Amplification as Resistance Mechanism of First-Line Osimertinib Treatment in a Patient with EGFR-Mutated NSCLC.

M. Tiseo, A. Leonetti, C. Lagrasta, 2018, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

A New ABCB1 Inhibitor Enhances the Anticancer Effect of Doxorubicin in Both In Vitro and In Vivo Models of NSCLC

M. Adorni, F. Bernini, L. Elviri, 2023, International journal of molecular sciences.

Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN

E. Giovannetti, G. Peters, A. Ardizzoni, 2017, Oncotarget.

MYC Amplification as a Potential Mechanism of Primary Resistance to Crizotinib in ALK-Rearranged Non-Small Cell Lung Cancer: A Brief Report12

M. Fiorentino, A. Ardizzoni, A. Ferrarini, 2018, Translational oncology.

Synergic activity of FGFR2 and MEK inhibitors in the treatment of FGFR2-amplified cancers of unknown primary

M. Ferracin, G. Calin, E. Porcellini, 2023, medRxiv.

Modulation of cell growth and host protein synthesis during HIV infection in vitro.

A. Di Rienzo, L. Montagnier, G. Piedimonte, 1992, Journal of Acquired Immune Deficiency Syndromes.

A sulfonyl fluoride derivative inhibits EGFRL858R/T790M/C797S by covalent modification of the catalytic lysine.

M. Tiseo, M. Mor, P. Petronini, 2021, European journal of medicinal chemistry.

Lung mesenchymal cells function as an inductive microenvironment for human lung cancer propagating cells†.

C. Lagrasta, E. Silini, P. Carbognani, 2014, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Roles of compatible osmolytes and heat shock protein 70 in the induction of tolerance to stresses in porcine endothelial cells

P. Petronini, R. Alfieri, M. Bonelli, 2004, The Journal of physiology.

Some questions about Eurocollins solution used for lung preservation.

L. Spaggiari, P. Carbognani, M. Rusca, 1994, The Journal of cardiovascular surgery.

The effect of the intracellular sodium level on the activity of amino acid transport systems L and A in SV40 3T3 cells.

S. Gandolfi, P. Petronini, A. Borghetti, 1985, Biochimica et biophysica acta.

The regulation by cell density of amino acid transport system L in SV40 3T3 cells.

G. Piedimonte, P. Petronini, A. Borghetti, 1982, Biochimica et biophysica acta.

Induction of amino acid transport activity in chick embryo fibroblasts by replacement of extracellular sodium chloride with disaccharide.

P. Petronini, A. Borghetti, K. Wheeler, 1990, Biochimica et biophysica acta.

Cell density and L-leucine transport in simian-virus-40-transformed 3T3 cells.

G. Piedimonte, P. Petronini, A. Borghetti, 1980, Biochemical Society Transactions.