B. Frangione

D. Selkoe, C. Masters, M. Benson, 1999, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Familial cerebral amyloid angiopathy (British type) with nonneuritic amyloid plaque formation may be due to a novel amyloid protein

G. Plant, T. Wisniewski, T. Révész, 1995, Journal of the Neurological Sciences.

The soluble form of Alzheimer's amyloid beta protein is complexed to high density lipoprotein 3 and very high density lipoprotein in normal human plasma.

E. Matsubara, J. Ghiso, B. Frangione, 1994, Biochemical and biophysical research communications.

Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers.

E. Matsubara, B. Zlokovic, J. Ghiso, 1996, Proceedings of the National Academy of Sciences of the United States of America.

The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex.

T. Wisniewski, E. Matsubara, J. Ghiso, 1993, The Biochemical journal.

HB-GAM, a Novel Amyloid Associated Protein, is Present in Prion Related Disorders and other Cerebral Amyloidoses

M. Lalowski, T. Wisniewski, M. Baumann, 1998 .

Distribution of the Protease Inhibitor α1Antichymotrypsin in Cerebral and Systemic Amyloid

M. Picken, M. Shelanski, B. Frangione, 1990 .

Brain uptake of circulating apolipoproteins J and E complexed to Alzheimer's amyloid beta.

T. Wisniewski, E. Matsubara, B. Zlokovic, 1994, Biochemical and biophysical research communications.

Fibrillogenesis in Alzheimer's disease of amyloid beta peptides and apolipoprotein E.

T. Wisniewski, C. Soto, A. Golabek, 1995, The Biochemical journal.

Familial cerebral amyloid angiopathies and dementia.

J. Ghiso, A. Rostagno, B. Frangione, 2000, Alzheimer disease and associated disorders.

Apolipoprotein J and Alzheimer's amyloid beta solubility.

C. Soto, E. Matsubara, J. Ghiso, 1996, The Biochemical journal.

Platelet Microparticles as Carriers of Soluble Alzheimer's Amyloid β (sAβ)

J. Ghiso, B. Frangione, T. Murakami, 2002 .

Neuropathology and Genetics of Prion Protein and British Cerebral Amyloid Angiopathies

B. Ghetti, J. Ghiso, B. Frangione, 2000 .

β-Protein deposition: a pathogenetic link between Alzheimer's disease and cerebral amyloid angiopathies

M. Shelanski, G. Bots, W. Luyendijk, 1988, Brain Research.

IgA proteases of two distinct specificities are released by Neisseria meningitidis

M. Mulks, B. Frangione, H. Feldman, 1980, The Journal of experimental medicine.

Relationship between the specificity of IgA proteases and serotypes in Haemophilus influenzae.

M. Mulks, B. Frangione, A. Plaut, 1982, The Journal of infectious diseases.

IgA proteases of two distinct specificities are released by Neisseria meningitidis

M. Mulks, B. Frangione, H. Feldman, 1980, The Journal of experimental medicine.

The amino acid sequence of a human immunoglobulin G3m(g) pFc' fragment.

B. Frangione, T. Michaelsen, E. Franklin, 1977, Journal of immunology.

A Simple Procedure of Immunochemical Detection of Amyloid β Proteins using Milligram Amounts of Brain Tissues of Patients with Alzheimer’s Disease

T. Wisniewski, M. Pras, B. Martin, 1998 .

Primary structure of the major coat protein of the filamentous bacterial viruses, If1 and Ike.

W. Konigsberg, R. L. Wiseman, Y. Nakashima, 1981, The Journal of biological chemistry.

Amyloid in familial amyloidosis, Finnish type, is antigenically and structurally related to gelsolin.

J. Palo, J. Ghiso, B. Frangione, 1990, The American journal of pathology.

Chemical typing of human immunoglobulins E And D

B. Frangione, S. Kochwa, E. Méndez, 1973, FEBS letters.

Familial cerebral amyloid angiopathy related to stroke and dementia.

J. Holton, T. Révész, N. Wood, 2001, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Nomenclature of amyloid and amyloidosis

G. Glenner, M. Kazatchkine, M. Benson, 1998 .

PrP Peptides as a Tool to Investigate the Pathogenesis of Prion Protein Amyloidoses

B. Ghetti, G. Forloni, F. Tagliavini, 1998 .

Synthetic peptides corresponding to different mutated regions of the amyloid gene in familial Creutzfeldt-Jakob disease show enhanced in vitro formation of morphologically different amyloid fibrils.

J. Ghiso, P. Brown, D. Gajdusek, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Alzheimer patients and Down patients: Abnormal presynaptic terminals are related to cerebral preamyloid deposits

B. Ghetti, B. Pollo, F. Tagliavini, 1990, Neuroscience Letters.

SINGLE PEPTIDE DIFFERENCES BETWEEN γ-GLOBULINS OF DIFFERENT GENETIC (Gm) TYPES

M. Meltzer, B. Frangione, E. Franklin, 1964 .

Nonamyloidotic monoclonal immunoglobulin deposits lack amyloid P component.

M. Picken, B. Frangione, J. Buxbaum, 1988, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

Immunohistochemical analysis of lattice corneal dystrophies types I and II.

A. Tarkkanen, J. Ghiso, T. Kivelä, 1993, The British journal of ophthalmology.

Immunohistochemical analysis of lattice corneal dystrophies

A. Tarkkanen, J. Ghiso, I. McLean, 2022 .

Identification of a New Prealbumin (Transthyretin) Variant in Cardiac Tissue: Immunologic and Biochemical Similarity to One Form of Familial Amyloidotic Polyneuropathy

M. Pras, B. Frangione, P. Gorevic, 1989 .

DNA diagnosis for hereditary cerebral hemorrhage with amyloidosis (Dutch type)

C. van Broeckhoven, W. Hul, E. Bakker, 1991, American journal of human genetics.

Platelet microparticles as carriers of soluble Alzheimer's amyloid beta (sAbeta).

E. Matsubara, M. Shoji, K. Abe, 2002, Annals of the New York Academy of Sciences.

Systemic and cerebral amyloidosis.

B. Frangione, Bias Frangione, 1989, Annals of medicine.

Human cerebral amyloidosis

B. Frangione, 1988 .

Variant of a human immunoglobulin: "alpha chain disease" protein AIT.

B. Frangione, C. Wolfenstein-Todel, E. Mihaesco, 1975, Biochemical and biophysical research communications.

"Alpha chain disease" protein def: internal deletion of a human immunoglobulin A1 heavy chain.

B. Frangione, C. Wolfenstein-Todel, E. Mihaesco, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Heavy chain diseases: clinical features and molecular significance of the disordered immunoglobulin structure.

B. Frangione, E. Franklin, 1973, Seminars in hematology.

Clearance systems in the brain—implications for Alzheimer disease

Thomas Wisniewski, Leon Axel, Els Fieremans, 2015, Nature Reviews Neurology.

Erratum: Clearance systems in the brain—implications for Alzheimer diseaser

C. Nicholson, K. Blennow, M. Leon, 2016 .

Transport-Clearance Hypothesis for Alzheimer's Disease and Potential Therapeutic Implications

B. Zlokovic, B. Frangione, 2013 .

Parenchymal preamyloid and amyloid deposits in the brains of patients with hereditary cerebral hemorrhage with amyloidosis—Dutch type

F. Tagliavini, B. Frangione, J. Haan, 1990, Neuroscience Letters.

Amyloid Fibrils in Hereditary Cerebral Hemorrhage with Amyloidosis (HCHWAS) is Related to Cystatin (Gamma Trace)

B. Frangione, Ó. Jensson, H. Feiner, 1986 .

Chemical typing of immunoglobulins.

C. Milstein, B. Frangione, E. Franklin, 1969, Nature.

Biochemical characterization of amyloid derived from the variable region of the kappa light chain subgroup III.

W. Pruzanski, M. Picken, B. Frangione, 1990, Arthritis and rheumatism.

Distinct patterns of heavy chain variable region subgroup use by human monoclonal autoantibodies of different specificity

G. Silverman, D. Carson, B. Frangione, 1988, The Journal of experimental medicine.

ASSOCIATION BETWEEN HUMAN IgM AUTOANTIBODIES AND κ CHAIN ALLOTYPES

B. Frangione, F. Goñi, F. Goñi, 1987, Journal of immunogenetics.

PrP27-30 is a normal soluble prion protein fragment released by human platelets.

B. Ghetti, F. Tagliavini, B. Frangione, 1996, Biochemical and biophysical research communications.

Sequencing of the Alzheimer's APP gene Dutch variant (APP‐D)

E. Levy, B. Frangione, I. Fernandez‐Madrid, 1993, Human mutation.

Different processing of Alzheimer's beta-protein precursor in the vessel wall of patients with hereditary cerebral hemorrhage with amyloidosis-Dutch type.

S. V. van Duinen, S. Duinen, G. Bots, 1988, Biochemical and biophysical research communications.

Primary structure of an amyloid prealbumin variant in familial polyneuropathy of Jewish origin.

M. Pras, B. Frangione, F. Prelli, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Immunoglobulin lambda light chains are the precursors of ureteral localized amyloidosis: a micromethod for extraction of amyloid

L. Morelli, B. Frangione, F. Prelli, 1997 .

Methods for Studying Prion Protein Amyloid

B. Ghetti, G. Forloni, F. Tagliavini, 1996 .

Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3.

A. Roses, R. Mahley, T. Wisniewski, 1994, The Journal of clinical investigation.

The defect in mu heavy chain disease protein GLI.

B. Frangione, F. Prelli, E. Franklin, 1976, Journal of immunology.

J chain is covalently bound to both monomer subunits in human secretory IgA.

B. Frangione, A. García-Pardo, A. Plaut, 1981, The Journal of biological chemistry.

Secretory component is convalently bound to a single sub-unit in human secretory IgA.

B. Frangione, A. Plaut, M. Lamm, 1979, Molecular immunology.

BRI2 Interacts with Amyloid Precursor Protein (APP) and Regulates Amyloid β (Aβ) Production*

J. Ghiso, Maria Tsachaki, A. Rostagno, 2005, Journal of Biological Chemistry.

The majority of human monoclonal IgM rheumatoid factors express a "primary structure-dependent" cross-reactive idiotype.

F. Jirik, D. Carson, B. Frangione, 1985, Journal of immunology.

Chromosome 13 dementia syndromes as models of neurodegeneration

G. Plant, J. Holton, T. Révész, 2001, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Human complex-forming glycoprotein, heterogeneous in charge: the primary structure around the cysteine residues and characterization of a disulfide bridge.

E. Méndez, B. Frangione, C. López, 1982, Archives of biochemistry and biophysics.

Antiidiotypic activity in the IgM fractions of mixed cryoglobulins.

B. Frangione, D. Geltner, E. Franklin, 1980, Journal of immunology.

Genetic Heterogeneity of Familial Amyloid Polyneuropathies of Jewish Type

M. Pras, B. Frangione, F. Prelli, 1986 .

Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred.

S. Prusiner, B. Ghetti, M. Farlow, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Apolipoprotein E Carboxyl-terminal Fragments Are Complexed to Amyloids A and L

M. Pras, B. Frangione, F. Prelli, 1995, The Journal of Biological Chemistry.

Characterization of High Molecular Weight Amyloid A Proteins

M. Pras, B. Frangione, F. Prelli, 1991, Scandinavian journal of immunology.

Clinical, Pathological, and Molecular Characterization of Gerstmann-Sträussler-Scheinker Disease in the Indiana Kindred ( PRNP F198S)

R. Yee, B. Ghetti, G. Hutchins, 1998 .

Amyloid Fibril Protein Nomenclature - 2002

C. Masters, M. Benson, M. Saraiva, 2002, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

The amino acid sequence of duck amyloid A (AA) protein.

M. Pras, B. Frangione, P. Gorevic, 1977, Journal of immunology.

Inhibition of Alzheimer β-Fibrillogenesis by Melatonin*

C. Soto, J. Ghiso, B. Frangione, 1998, The Journal of Biological Chemistry.

In vitro formation of amyloid fibrils from two synthetic peptides of different lengths homologous to Alzheimer's disease β-protein

J. Ghiso, A. Migheli, B. Frangione, 1986 .

Regulation and genetic control of brain amyloid

S. Prusiner, D. Price, C. Masters, 1991, Brain Research Reviews.

Proteolytic enzymes from the mouse submaxillary gland. Specificity restricted to arginine residues.

B. Frangione, E. Franklin, I. Schenkein, 1977, Archives of biochemistry and biophysics.

Nomenclature of amyloid fibril proteins. Report from the meeting of the98. Part 1 [editorial]

D. Selkoe, C. Masters, R. Kyle, 1999 .

Amyloid: Toward terminology clarification Report from the Nomenclature Committee of the International Society of Amyloidosis

Giampaolo Merlini, Colin L Masters, Shu-Ichi Ikeda, 2005, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Immunohistochemical and Biochemical Characterization

M. Picken, K. Pelton, B. Frangione, 2007 .

Isolation and partial characterization of SAA-an amyloid-related protein from human serum.

C. J. Rosenthal, B. Frangione, E. Franklin, 1976, Journal of immunology.

The spectrum of monoclonal immunoglobulin deposition disease associated with immunocytic dyscrasias.

M. Picken, B. Frangione, J. Buxbaum, 1989, Seminars in hematology.

Nodular cutaneous amyloidosis.

M. Pras, B. Frangione, F. Prelli, 1991, The American Journal of dermatopathology.

B. Frangione, G. Gallo, D. Cohen, 2007 .

B. Frangione, G. Gallo, D. Cohen, 1983, The American journal of pathology.

Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation.

C. Soto, M. Baumann, M. Kindy, 1996, Biochemical and biophysical research communications.

Amyloid arthropathy: characterization of the amyloid protein.

M. Itzchaki, M. Pras, B. Frangione, 1985, Clinical and experimental rheumatology.

Beta-2 microglobulin is an amyloidogenic protein in man.

B. Frangione, P. Gorevic, F. Prelli, 1985, The Journal of clinical investigation.

Nucleotide sequence of the small double-stranded RNA segment of bacteriophage phi 6: novel mechanism of natural translational control

L. Mindich, B. Frangione, T. McGraw, 1986, Journal of virology.

Human monoclonal macroglobulins with specificity for Klebsiella K polysaccharides that contain 3,4-pyruvylated-D-galactose and 4,6- pyruvylated-D-galactose

E. Kabat, E. Osserman, B. Frangione, 1980, The Journal of experimental medicine.

Primary structure of human plasma fibronectin. The 29,000-dalton NH2-terminal domain.

B. Frangione, A. García-Pardo, E. Pearlstein, 1983, The Journal of biological chemistry.

Variations in the S—S bridges of immunoglobins G: Interchain disulphide bridges of γG3 myeloma proteins

C. Milstein, B. Frangione, 1968 .

Isolation and amino terminal sequence of β-trace, a novel protein from human cerebrospinal fluid

J. Ghiso, B. Frangione, E. Castaño, 1991, Brain Research.

Isolation and amino terminal sequence of beta-trace, a novel protein from human cerebrospinal fluid.

J. Ghiso, B. Frangione, E. Castaño, 1991, Brain research.

Clusterin and Alzheimer's disease.

Agueda Rostagno, Jorge Ghiso, J. Ghiso, 2005, Sub-cellular biochemistry.

Biochemical and immunological characterization of three binding sites on human plasma fibronectin with different affinities for heparin.

L. Gold, B. Frangione, E. Pearlstein, 1983, Biochemistry.

Primary structure of human plasma fibronectin--characterization of the 6,000 dalton C-terminal fragment containing the interchain disulfide bridges.

B. Frangione, A. García-Pardo, E. Pearlstein, 1984, Biochemical and biophysical research communications.

Fibronectin binds to amyloid P component. Localization of the binding site to the 31,000 dalton C-terminal domain.

A. Rostagno, B. Frangione, A. García-Pardo, 1986, Biochemical and biophysical research communications.

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier.

D. Holtzman, J. Bading, B. Zlokovic, 2000, The Journal of clinical investigation.

Amino acid sequence similarities between amyloid P component C1t and CRP

Y. Levo, B. Frangione, E. Franklin, 1977, Nature.

Biochemical studies on the interaction of fibronectin with Ig.

L. Gold, A. Rostagno, B. Frangione, 1991, Journal of immunology.

Polymerization of intact beta 2-microglobulin in tissue causes amyloidosis in patients on chronic hemodialysis.

B. Frangione, P. Gorevic, F. Prelli, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Unifying features of systemic and cerebral amyloidosis

T. Wisniewski, J. Ghiso, B. Frangione, 1994, Molecular Neurobiology.

Biochemical analysis of the interaction of fibronectin with IgG and localization of the respective binding sites.

L. Gold, A. Rostagno, B. Frangione, 1996, Molecular immunology.

Biochemical characterization of the fibronectin binding sites for IgG.

L. Gold, A. Rostagno, B. Frangione, 1989, Journal of immunology.

The amino‐terminal sequence of human protein HC

B. Frangione, E. Franklin, A. Grubb, 1976, FEBS letters.

Substitution at codon 22 reduces clearance of Alzheimer’s amyloid-β peptide from the cerebrospinal fluid and prevents its transport from the central nervous system into blood

B. Zlokovic, J. Ghiso, M. Calero, 2002, Neurobiology of Aging.

Subtilisin and cyanogen bromide cleavage products of fibronectin that retain gelatin-binding activity.

B Frangione, L. Gold, B. Frangione, 1979, Proceedings of the National Academy of Sciences of the United States of America.

RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain

Ann Marie Schmidt, Berislav Zlokovic, David Stern, 2003, Nature Medicine.

CEREBRAL AMYLOID ANGIOPATHY AND ALZHEIMER'S DISEASE.

T. Révész, J. Ghiso, A. Rostagno, 2010, Hirosaki igaku = Hirosaki medical journal.

Expression of BRI2 mRNA and protein in normal human brain and familial British dementia: its relevance to the pathogenesis of disease

T. Révész, N. Wood, A. Lees, 2008, Neuropathology and applied neurobiology.

Genetic alterations of the BRI2 gene: familial British and Danish dementias.

J. Holton, T. Révész, H. Braendgaard, 2006, Brain pathology.

Familial Danish Dementia: A Novel Form of Cerebral Amyloidosis Associated with Deposition of Both Amyloid‐Dan and Amyloid‐Beta

G. Plant, T. Révész, C. Strand, 2002, Journal of neuropathology and experimental neurology.

Sequence, genomic structure and tissue expression of Human BRI3, a member of the BRI gene family.

T. Révész, J. Ghiso, M. Calero, 2001, Gene.

A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred.

T Bek, T Revesz, A Rostagno, 2000, Proceedings of the National Academy of Sciences of the United States of America.

A stop-codon mutation in the BRI gene associated with familial British dementia

Agueda Rostagno, Jorge Ghiso, Ruben Vidal, 1999, Nature.

An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: implications for Alzheimer's disease

R. Reiter, B. Poeggeler, J. Ghiso, 2000, Journal of Neural Transmission.

Biology of Aβ Amyloid in Alzheimer's Disease

T. Wisniewski, J. Ghiso, B. Frangione, 1997, Neurobiology of Disease.

Molecular biology of brain aging and neurodegenerative disorders.

T. Wisniewski, B. Frangione, 1996, Acta neurobiologiae experimentalis.

Apolipoprotein E and amyloidogenesis.

T. Wisniewski, J. Ghiso, B. Frangione, 1996, Ciba Foundation symposium.

S182 protein in Alzheimer's disease neuritic plaques

T. Wisniewski, J. Palha, J. Ghiso, 1995, The Lancet.

Amino acid sequence of the protein inhibitor of mitochondrial adenosine triphosphatase.

H. Penefsky, B. Frangione, M. E. Pullman, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Novel prion protein conformation and glycotype in Creutzfeldt-Jakob disease.

M. D. Di Bari, R. Nonno, U. Agrimi, 2007, Archives of neurology.

Systemic senile amyloidosis. Identification of a new prealbumin (transthyretin) variant in cardiac tissue: immunologic and biochemical similarity to one form of familial amyloidotic polyneuropathy.

M. Pras, B. Frangione, P. Gorevic, 1989, The Journal of clinical investigation.

Structure of immunoglobulin A. II. Sequence around the hinge region and labile disulfide bonds of an immunoglobulin A2 myeloma protein.

B. Frangione, E. Franklin, C. Wolfenstein‐Todel, 1972, Biochemistry.

Heavy-light chain disulphide bridge common to A1 and a genetic variant of A2 immunoglobulins.

B. Frangione, E. Mihaescon, M. Seligman, 1971, Nature: New biology.

Characterization of a disulfide bridge linking the J chain to the alpha chain of polymeric immunoglobulin A.

B. Frangione, F. Prelli, E. Franklin, 1973, Biochemical and biophysical research communications.

Structure of immunoglobulin A. Amino acid sequence of cysteine-containing peptides from the J chain.

B. Frangione, E. Franklin, E. Méndez, 1973, Biochemistry.

Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies

G. Plant, T. Révész, J. Holton, 2009, Acta Neuropathologica.

Staphylococcal Protein A and Human IgG Subclasses and Allotypes

B. Frangione, E. Franklin, E. Loghem, 1982, Scandinavian journal of immunology.

The Defect in µ Heavy Chain Disease Protein GLI

B. Frangione, F. Prelli, E. Franklin, 1976, The Journal of Immunology.

Structural variants of human and murine immunoglobulins.

B. Frangione, E. Franklin, 1975, Contemporary topics in molecular immunology.

Human lambda light-chain constant region gene CMor lambda: the primary structure of lambda VI Bence Jones protein Mor.

T. Moloshok, A. Solomon, B. Frangione, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Intact Alzheimer amyloid precursor protein (APP) is present in platelet membranes and is encoded by platelet mRNA.

J. Ghiso, J. Gardella, A. Kaplan, 1990, Biochemical and biophysical research communications.

Sporadic and Familial Cerebral Amyloid Angiopathies

Janice L Holton, Tamas Revesz, Agueda Rostagno, 2002, Brain pathology.

Purification, characterization, and immunolocalization of paramyosin from the adult stage of Fasciola hepatica

B. Frangione, F. Goñi, M. Cancela, 2004, Parasitology Research.

Melatonin reverses the profibrillogenic activity of apolipoprotein E4 on the Alzheimer amyloid Abeta peptide.

B Frangione, J Ghiso, T. Wisniewski, 2001, Biochemistry.

Human Immunoglobulin Mutants

B. Frangione, E. Franklin, 1979 .

Characterization of amyloid deposits and P component from a patient with factor X deficiency reveals proteins derived from a lambda VI light chain.

M. Pras, B. Frangione, E. Franklin, 1983, The American journal of medicine.

Hereditary cystatin C (γ‐trace) amyloid angiopathy of the CNS causing cerebral hemorrhage

B. Frangione, Ó. Jensson, A. Grubb, 1987 .

Differences Between Vascular and Plaque Core Amyloid in Alzheimer's Disease

G. Glenner, B. Frangione, F. Prelli, 1988, Journal of neurochemistry.

Gelsolin gene mutation--at codon 187--in familial amyloidosis, Finnish: DNA-diagnostic assay.

E. Levy, B. Frangione, M. Haltia, 1992, American journal of medical genetics.

Mutation in gelsolin gene in Finnish hereditary amyloidosis

J. Ghiso, E. Levy, B. Frangione, 1990, The Journal of experimental medicine.

Amyloid protein in familial amyloidosis (Finnish type) is homologous to gelsolin, an actin-binding protein.

J. Palo, J. Ghiso, B. Frangione, 1990, Biochemical and biophysical research communications.

Gelsolin variant (Asn-187) in familial amyloidosis, Finnish type.

J. Ghiso, J. Novello, B. Frangione, 1990, The Biochemical journal.

Complement Activation in Chromosome 13 Dementias

G. Plant, T. Révész, J. Holton, 2002, The Journal of Biological Chemistry.

Ocular amyloid deposition in familial amyloidosis, Finnish: an analysis of native and variant gelsolin in Meretoja's syndrome.

A. Tarkkanen, J. Ghiso, T. Kivelä, 1994, Investigative ophthalmology & visual science.

Cerebral amyloidosis, amyloid angiopathy, and their relationship to stroke and dementia.

Jorge Ghiso, J. Ghiso, B. Frangione, 2001, Journal of Alzheimer's disease : JAD.

Amyloid fibrils in Gerstmann-Sträussler-Scheinker disease (Indiana and Swedish Kindreds) express only PrP peptides encoded by the mutant allele

B. Ghetti, M. Farlow, F. Tagliavini, 1994, Cell.

Inherited amyloids of the nervous system

T. Wisniewski, B. Frangione, E. Castaño, 1991, Current Opinion in Neurobiology.

The primary structure of the Fab fragment of protein KAU, a monoclonal immunoglobulin M cold agglutinin.

J. Leoni, J. Ghiso, B. Frangione, 1991, The Journal of biological chemistry.

Light chain deposition disease derived from the kappa I light chain subgroup. Biochemical characterization.

B. Barlogie, M. Picken, B. Frangione, 1989, The American journal of pathology.

Somatic mutations of the L12a gene in V-kappa(1) light chain deposition disease: potential effects on aberrant protein conformation and deposition.

J. Ghiso, F. Stevens, B. Frangione, 1999, The American journal of pathology.

Light chain cardiomyopathy. Structural analysis of the light chain tissue deposits.

J. Ghiso, F. Stevens, B. Frangione, 1996, The American journal of pathology.

Structural and idiotypic characterization of the L chains of human IgM autoantibodies with different specificities.

D. Carson, A. Solomon, B. Frangione, 1989, Journal of immunology.

Amino‐terminal identity of co‐existent amyloid and non‐amyloid immunoglobulin κ light chain deposits. A human disease to study alterations of protein conformation

J. Ghiso, B. Frangione, R. Vidal, 1997, Clinical and experimental immunology.

Kappa light chain-associated Fanconi's syndrome: molecular analysis of monoclonal immunoglobulin light chains from patients with and without intracellular crystals.

L. Denoroy, F. Stevens, B. Frangione, 1999, Protein engineering.

The structure of immunoglobulins and their genes, DNA rearrangement and B cell differentiation, molecular anomalies of some monoclonal immunoglobulins.

B. Frangione, J. Buxbaum, S. Rosen, 1986, Seminars in oncology.

Characterization of renal amyloid derived from the variable region of the lambda light chain subgroup II.

M. Picken, B. Frangione, J. Buxbaum, 1986, The American journal of pathology.

Apolipoprotein E: A pathological chaperone protein in patients with cerebral and systemic amyloid

Thomas Wisniewski, T. Wisniewski, B. Frangione, 1992, Neuroscience Letters.

Two serologically distinguishable subclasses of mu-chains of human macroglobulins.

B. Frangione, E. Franklin, Edward C. Franklin, 1967, Journal of immunology.

Idiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans.

G. Silverman, R. Jefferis, D. Carson, 1988, The Journal of clinical investigation.

Production of the Alzheimer amyloid beta protein by normal proteolytic processing.

S. Estus, T. Golde, M. Shoji, 1992, Science.

Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues.

B. Ghetti, F. Tagliavini, P. Lievens, 1998, The American journal of pathology.

The heterogeneity of bovine IgG2--V. Differences in the primary structure of bovine IgG2 allotypes.

J. Butler, B. Frangione, H. Heyermann, 1992, Molecular immunology.

Down patients: Extracellular preamyloid deposits precede neuritic degeneration and senile plaques

C. Bouras, F. Tagliavini, O. Bugiani, 1989, Neuroscience Letters.

Structure of Human Immunoglobulins and their Variants

B. Frangione, 1975 .

Split immunoglobulin genes and human heavy chain deletion-mutants.

B. Frangione, E. Franklin, 1979, Journal of Immunology.

Disulphide bridges of the heavy chain of human immunoglobulin G2.

C. Milstein, B. Frangione, 1971, Biochemical Journal.

Structural studies of immunoglobulin G.

C. Milstein, B. Frangione, J. Pink, 1969, Nature.

Plaque-Associated Overexpression of Insulin-Degrading Enzyme in the Cerebral Cortex of Aged Transgenic Tg2576 Mice With Alzheimer Pathology

E. Sigurdsson, T. Wisniewski, L. Morelli, 2006, Journal of neuropathology and experimental neurology.

Immunoglobulins: Structural Studies of Immunoglobulin G

C. Milstein, B. Frangione, J. R. Pink, 1969, Nature.

Structure of Atypical Immunoglobulins—Relationship to Genetic Control Mechanisms

B. Frangione, 1978 .

The molecular defect in a protein (CRA) found in gamma-1 heavy chain disease, and its genetic implications.

B. Frangione, E. Franklin, 1971, Proceedings of the National Academy of Sciences of the United States of America.

Correlation of protein structure and immunoglobulin gene organization in the light of two new deleted heavy chain disease proteins.

B. Frangione, E. Franklin, M. Seligmann, 1979, Molecular immunology.

Molecular Defect in a Gamma-2 (γ2) Heavy Chain

B. Frangione, E. Franklin, Sheldon M. Cooper, 1972, Science.

Primary structure of human gamma 3 immunoglobulin deletion mutant: gamma 3 heavy-chain disease protein Wis.

B. Frangione, F. Prelli, E. Franklin, 1980, Biochemistry.

Circulating amyloid-beta peptide crosses the blood-brain barrier in aged monkeys and contributes to Alzheimer's disease lesions.

T. Wisniewski, J. Bading, B. Zlokovic, 2002, Vascular pharmacology.

Characterization of human rheumatoid factors with seven antiidiotypes induced by synthetic hypervariable region peptides

R. Houghten, D. Carson, B. Frangione, 1985, The Journal of experimental medicine.

Vascular Transport of Alzheimer’s Amyloid β Peptides and Apolipoproteins

B. Zlokovic, J. Ghiso, B. Frangione, 2000 .

Alzheimer's disease and soluble Aβ

T. Wisniewski, J. Ghiso, B. Frangione, 1994, Neurobiology of Aging.

Epitope map of two polyclonal antibodies that recognize amyloid lesions in patients with Alzheimer's disease.

T. Wisniewski, J. Ghiso, A. Rostagno, 1992, The Biochemical journal.

Peptides homologous to the amyloid protein of Alzheimer's disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation.

T. Wisniewski, J. Ghiso, B. Frangione, 1991, Biochemical and biophysical research communications.

Biology of Disease Human Amyloidosis, Alzheimer Disease and Related Disorders

B. Frangione, E. Castaño, 1989 .

Ten to fourteen residue peptides of Alzheimer's disease protein are sufficient for amyloid fibril formation and its characteristic x-ray diffraction pattern.

B. Frangione, P. Gorevic, E. Castaño, 1987, Biochemical and biophysical research communications.

Soluble Aβ homeostasis in AD and DS: impairment of anti-amyloidogenic protection by lipoproteins

S. Hirai, T. Tokuda, E. Matsubara, 2004, Neurobiology of Aging.

The 1990 Guidelines for Nomenclature and Classification of Amyloid and Amyloidosis

G. Glenner, M. Benson, P. Westermark, 1991 .

Chromosome 13 dementias

J. Holton, T. Révész, J. Ghiso, 2005, Cellular and Molecular Life Sciences CMLS.

Binding of cystatin C to Alzheimer’s amyloid β inhibits in vitro amyloid fibril formation

S. Schmidt, P. Mathews, R. Nixon, 2004, Neurobiology of Aging.

Amyloidosis and Alzheimer's disease.

J. Ghiso, B. Frangione, 2002, Advanced drug delivery reviews.

Senile dementia associated with amyloid β protein angiopathy and tau perivascular pathology but not neuritic plaques in patients homozygous for the APOE-ε4 allele

Bradley T. Hyman, Ronald Beavis, Martin R. Farlow, 2000, Acta Neuropathologica.

The length of Amyloid-β in Hereditary Cerebral Hemorrhage with Amyloidosis, Dutch Type

R. Beavis, C. Soto, E. Matsubara, 1996, The Journal of Biological Chemistry.

Tau protein directly interacts with the amyloid β-protein precursor: Implications for Alzheimer's disease

R. Kalaria, F. Tagliavini, O. Bugiani, 1995, Nature Medicine.

Two conformational states of amyloid β-peptide: implications for the pathogenesis of Alzheimer's disease

C. Soto, B. Frangione, 1995, Neuroscience Letters.

Early onset Alzheimer's disease in a South American pedigree from Argentina

P. Gorelick, T. Wisniewski, C. Mangone, 1995, Acta neurologica Scandinavica.

APP processing, Aβ-amyloidogenesis, and the pathogenesis of Alzheimer's disease

P. Greengard, J. Buxbaum, S. Gandy, 1994, Neurobiology of Aging.

Preamyloid deposits in the cerebral cortex of patients with Alzheimer's disease and nondemented individuals

F. Tagliavini, O. Bugiani, B. Frangione, 1988, Neuroscience Letters.

Human Amyloidosis and In Vitro Formation of Alzheimer Amyloid Fibrils

B. Frangione, E. Castaño, 1987 .

Structure of immunoglobulin A. Cysteine-containing peptides of the alpha chain of an immunoglobulin A-1 myeloma protein.

B. Frangione, E. Franklin, E. Méndez, 1973, Biochemistry.

Proteinase-K-Resistant Prion Protein Isoforms in Gerstmann-Straussler-Scheinker Disease (Indiana Kindred)

B. Ghetti, F. Tagliavini, O. Bugiani, 1996, Journal of neuropathology and experimental neurology.

Chaperoning Alzheimer's amyloids

T. Wisniewski, J. Ghiso, B. Frangione, 1994, Neurobiology of Aging.

Gelsolin immunoreactivity in corneal amyloid, wound healing, and macular and granular dystrophies.

T. Wisniewski, B. Frangione, P. Gorevic, 1993, American journal of ophthalmology.

Stroke in Icelandic patients with hereditary amyloid angiopathy is related to a mutation in the cystatin C gene, an inhibitor of cysteine proteases

C. López-Otín, J. Ghiso, E. Levy, 1989, The Journal of experimental medicine.

Immunization delays the onset of prion disease in mice.

E. Sigurdsson, T. Wisniewski, David R. Brown, 2002, The American journal of pathology.

Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice.

B Frangione, E. Sigurdsson, T. Wisniewski, 2001, The American journal of pathology.

Cross-reacting idiotypes on cryoprecipitating rheumatoid factor

Pojen P. Chen, G. Silverman, D. Carson, 2005, Springer Seminars in Immunopathology.

Apolipoprotein E : binding to soluble Alzheimer's β-amyloid

T. Wisniewski, E. Matsubara, J. Ghiso, 1993 .

A 7-kDa Prion Protein (PrP) Fragment, an Integral Component of the PrP Region Required for Infectivity, Is the Major Amyloid Protein in Gerstmann-Sträussler-Scheinker Disease A117V*

B. Ghetti, R. Beavis, F. Tagliavini, 2001, The Journal of Biological Chemistry.

Copper Chelation Delays the Onset of Prion Disease*

E. Sigurdsson, T. Wisniewski, David R. Brown, 2003, Journal of Biological Chemistry.

Erratum: Prion protein preamyloid and amyloid deposits in Gerstmann- Straussler-Scheinker disease, Indiana kindred (Proc. Natl. Acad. Sci. USA (October 1, 1992) 89:19 (9349-9353))

S. Prusiner, B. Ghetti, M. Farlow, 1993 .

Anti-prion antibodies for prophylaxis following prion exposure in mice

E. Sigurdsson, T. Wisniewski, R. Carp, 2003, Neuroscience Letters.

Cell-lysate conversion of prion protein into its protease-resistant isoform suggests the participation of a cellular chaperone.

C. Soto, D. Harris, E. Levy, 1999, Biochemical and biophysical research communications.

The prionoses and other conformational disorders.

T. Wisniewski, C. Soto, B. Frangione, 1998, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia.

L. Martinian, T. Révész, J. Holton, 2001, The American journal of pathology.

A primer of amyloid nomenclature

C. Masters, M. Benson, M. Saraiva, 2007, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Fate of Cerebrospinal Fluid‐Borne Amyloid β‐Peptide: Rapid Clearance into Blood and Appreciable Accumulation by Cerebral Arteries

C. Patlak, J. Ghersi-Egea, J. Ghiso, 1996, Journal of neurochemistry.

B. Pons-Estel, A. Solomon, B. Frangione, 1984, The Journal of experimental medicine.

B. Pons-Estel, A. Solomon, B. Frangione, 1984 .

The disulphide bonds of the heavy chain of rabbit immunoglobulin G.

R. Porter, B. Frangione, I. O'donnell, 1970, The Biochemical journal.

Protein Hal: partial deletion of a " " immunoglobulin gene(s) and apparent reinitiation at an internal AUG codon.

E. Haber, B. Frangione, K. Bloch, 1973, Proceedings of the National Academy of Sciences of the United States of America.

Light Chain Variable Region Subgroups of Monoclonal Immunoglobulins in Amyloidosis AL

R. Kyle, A. Solomon, B. Frangione, 1986 .

Functional and structural properties of lipid-associated apolipoprotein J (clusterin).

B. Zlokovic, J. Ghiso, M. Calero, 1999, The Biochemical journal.

Preferential association of serum amyloid P component with fibrillar deposits in familial British and Danish dementias: Similarities with Alzheimer's disease

G. Plant, T. Révész, J. Holton, 2007, Journal of the Neurological Sciences.

A safer vaccine for Alzheimer’s disease?

E. Sigurdsson, T. Wisniewski, B. Frangione, 2002, Neurobiology of Aging.

The “Nonamyloidogenic” p3 Fragment (Amyloid β17-42) Is a Major Constituent of Down's Syndrome Cerebellar Preamyloid*

H. Wiśniewski, D. Selkoe, M. Lalowski, 1996, The Journal of Biological Chemistry.

Clearance of amyloid beta-peptide from brain: transport or metabolism?

D. Holtzman, B. Zlokovic, J. Ghiso, 2000, Nature medicine.

Fibrillogenesis of synthetic amyloid-β peptides is dependent on their initial secondary structure

R. Beavis, C. Soto, B. Frangione, 1995, Neuroscience Letters.

Vaccination of Alzheimer's model mice with Aβ derivative in alum adjuvant reduces Aβ burden without microhemorrhages

D. Quartermain, E. Sigurdsson, T. Wisniewski, 2006, The European journal of neuroscience.

Systemic Amyloid Deposits in Familial British Dementia*

T Lashley, T Revesz, A Rostagno, 2001, The Journal of Biological Chemistry.

Title Pyroglutamate formation at the N-termini of ABri molecules in familial British dementia is not restricted to the central nervous system

T. Révész, J. Ghiso, A. Tamaoka, 2016 .

PYROGLUTAMATE FORMATION AT THE N-TERMINI OF ABRI MOLECULES IN FAMILIAL BRITISH DEMENTIA IS NOT RESTRICTED TO THE CENTRAL NERVOUS SYSTEM.

T. Révész, J. Holton, J. Ghiso, 2010, Hirosaki igaku = Hirosaki medical journal.

High-level expression and in vitro mutagenesis of a fibrillogenic 109-amino-acid C-terminal fragment of Alzheimer's-disease amyloid precursor protein.

J. Ghiso, J. Gardella, B. Frangione, 1993, The Biochemical journal.

Alzheimer's β‐amyloid vasoactivity: identification of a novel β‐amyloid conformational intermediate

C. Soto, M. Mullan, F. Crawford, 1998 .

Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro.

T Vogel, B Frangione, T. Wisniewski, 1994, The American journal of pathology.

Reversion of prion protein conformational changes by synthetic b-sheet breaker peptides

T. Wisniewski, C. Soto, F. Tagliavini, 2000, The Lancet.

Familial Danish Dementia

G. Plant, T. Révész, J. Holton, 2005, Journal of Biological Chemistry.

Familial British dementia with amyloid angiopathy: early clinical, neuropsychological and imaging findings.

S. Mead, T. Révész, J. Ghiso, 2000, Brain : a journal of neurology.

Iowa variant of familial Alzheimer's disease: accumulation of posttranslationally modified AbetaD23N in parenchymal and cerebrovascular amyloid deposits.

Yun Lu, S. Greenberg, J. Ghiso, 2010, The American journal of pathology.

Substitutions at codon 22 of Alzheimer's abeta peptide induce diverse conformational changes and apoptotic effects in human cerebral endothelial cells.

B Frangione, J Ghiso, F. Tagliavini, 2000, The Journal of biological chemistry.

Cerebrovascular Accumulation and Increased Blood‐Brain Barrier Permeability to Circulating Alzheimer's Amyloid β Peptide in Aged Squirrel Monkey with Cerebral Amyloid Angiopathy

J. Bading, B. Zlokovic, J. Ghiso, 1998, Journal of neurochemistry.

Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides.

A Rostagno, B Frangione, J Ghiso, 2000, The Biochemical journal.

Molecular chaperons, amyloid and preamyloid lesions in the BRI2 gene‐related dementias: a morphological study

T. Révész, M. Verbeek, J. Holton, 2006, Neuropathology and applied neurobiology.

Isolation and characterization of amyloid P component from Alzheimer's disease and other types of cerebral amyloidosis.

S. V. van Duinen, M. Shelanski, B. Frangione, 1988, Laboratory investigation; a journal of technical methods and pathology.

Insertion of influenza M protein into the viral lipid bilayer and localization of site of insertion

B. Frangione, A. Gregoriades, 1981, Journal of virology.

Immunological and Anti‐Chaperone Therapeutic Approaches for Alzheimer Disease

T. Wisniewski, B. Frangione, 2005, Brain pathology.

Association of human lambda light chain V/J/C segments: serologic analysis and primary structure of the lambda VI Bence Jones protein THO.

J. Ghiso, A. Solomon, B. Frangione, 1986, Journal of immunology.

Primary structure of the variable region of a human lambda VI light chain: Bence Jones protein SUT.

T. Moloshok, A. Solomon, B. Frangione, 1983, Journal of immunology.

The primary structure of human tissue amyloid P component from a patient with primary idiopathic amyloidosis.

M. Pras, B. Frangione, F. Prelli, 1985, The Journal of biological chemistry.

The -Helical to -Strand Transition in the Amino-terminal Fragment of the Amyloid -Peptide Modulates Amyloid Formation *

C. Soto, N. Inestrosa, B. Frangione, 1995, The Journal of Biological Chemistry.

Systemic Catabolism of Alzheimer's Aβ40 and Aβ42*

S. Gandy, J. Ghiso, M. Calero, 2004, Journal of Biological Chemistry.

An unusual papain fragment containing the V H region of an IgG3 myeloma protein.

F. Dammacco, B. Frangione, E. Franklin, 1972, Journal of immunology.

ANTIGENICITY OF HEREDITARY GAMMA GLOBULIN (GM) FACTORS -- BIOLOGICAL AND BIOCHEMICAL ASPECTS.

E. Stiehm, M. Meltzer, B. Frangione, 1964, Cold Spring Harbor Symposia on Quantitative Biology.

Polymorphism of tissue and serum amyloid A (AA and SAA) proteins in the mouse.

Y. Levo, B. Frangione, P. Gorevic, 1978, Journal of immunology.

GREATER RISK OF ALZHEIMER'S DISEASE IN OLDER ADULTS WITH INSOMNIA

M. D. de Leon, P. Martínez-Martín, L. Glodzik, 2011, Journal of the American Geriatrics Society.

A variant of prealbumin from amyloid fibrils in familial polyneuropathy of Jewish origin

M. Pras, B. Frangione, F. Prelli, 1981, The Journal of experimental medicine.

Detection of apolipoprotein E/dimeric soluble amyloid beta complexes in Alzheimer's disease brain supernatants.

B. Permanne, T. Wisniewski, C. Soto, 1997, Biochemical and biophysical research communications.

Expression of allelic and non‐allelic genes in immunoglobulin light chains from homozygous rabbits

B. Frangione, M. Lamm, 1970, FEBS letters.

Is Alzheimer's disease an apolipoprotein E amyloidosis?

M. Lalowski, T. Wisniewski, A. Golabek, 1995, The Lancet.

Brain Clearance of Alzheimer's Amyloid-β40 in the Squirrel Monkey: A SPECT Study in a Primate Model of Cerebral Amyloid Angiopathy

J. Bading, B. Zlokovic, J. Ghiso, 2002, Journal of drug targeting.

Human amyloidosis, Alzheimer disease and related disorders.

B. Frangione, E. Castaño, E. M. Castaño, 1988, Laboratory investigation; a journal of technical methods and pathology.

Point Mutation in Autosomal Dominant Forms of Amyloidosis

B. Frangione, 1991 .

Antibodies directed to the carboxyl terminus of amyloid β-peptide recognize sequence epitopes and distinct immunoreactive deposits in Alzheimer's disease brain

J. Ghiso, J. Albar, E. Méndez, 1998 .

In Vivo Reversal of Amyloid‐β Lesions in Rat Brain

B. Permanne, E. Sigurdsson, T. Wisniewski, 2000 .

In vivo reversal of amyloid-beta lesions in rat brain.

B. Permanne, E. Sigurdsson, T. Wisniewski, 2000, Journal of neuropathology and experimental neurology.

Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred

S. Prusiner, B. Ghetti, M. Farlow, 1992, Neurobiology of Aging.

Intrachain disulphide bridges in immunoglobulin G heavy chains. The Fc fragment.

C. Milstein, B. Frangione, E. Franklin, 1968, The Biochemical journal.

Insulin-degrading enzyme degrades amyloid peptides associated with British and Danish familial dementia.

G. de Prat-Gay, J. Ghiso, L. Morelli, 2005, Biochemical and biophysical research communications.

Isolation and Partial Characterization of Neurofibrillary Tangles and Amyloid Plaque Core in Alzheimer's Disease: Immunohistological Studies

B. Frangione, P. Gorevic, F. Goñi, 1986, Journal of neuropathology and experimental neurology.

Peptides et compositions pharmaceutiques a base de tels peptides, destinees au traitement de troubles ou d'affections associees a un pliage anormal de proteine dans des depots amyloides ou de type amyloide

M. Baumann, B. Frangione, Claudio Soto-Jara, 1996 .

Peptides Inhibitor of Amyloidogenesis in Alzheimer’s Disease

C. Soto, M. Kindy, B. Frangione, 1997 .

Correlation of the c‐terminal sequence of rabbit light chains with allotypes

B. Frangione, 1969, FEBS letters.

Intrachain disulphide bridges of rabbit immunoglobulin light chains of allotypes b4 and b5.

B. Frangione, M. Lamm, 1972, Biochemical Journal.

Peptide differences in purified mouse antibodies.

B. Benacerraf, B. Frangione, E. Franklin, 1967, Immunochemistry.

L chain peptide maps of rabbit IgG of different allotypes.

B. Frangione, E. Franklin, A. Kelus, 1968, Immunology.

Chaperoning Amyloid in Alzheimer’s Disease: The Art of Avoiding Sticky Situations?

T. Wisniewski, C. Soto, J. Ghiso, 1996 .

ßPP Participates in PrP-Amyloid Plaques of Gerstmann-Sträussler-Scheinker Disease, Indiana Kindred

B. Pollo, M. Farlow, O. Bugiani, 1993, Journal of neuropathology and experimental neurology.

B. Pons-Estel, D. Carson, B. Frangione, 1985, Journal of immunology.

Antibody response and plasma A β 1-40 levels in young Microcebus murinus primates immunized with A β 1-42 and its derivatives

S. Trouche, E. Sigurdsson, B. Frangione, 2009 .

Relation of the amyloid beta protein precursor to heparan sulfate proteoglycans.

D. Gowda, R. U. Margolis, J. Ghiso, 1989, Science.

BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production.

J. Ghiso, Maria Tsachaki, A. Rostagno, 2005, The Journal of biological chemistry.

Lipoprotein‐free amyloidogenic peptides in plasma are elevated in patients with sporadic Alzheimer's disease and Down's syndrome

E. Matsubara, K. Okamoto, M. Amari, 1999, Annals of neurology.

Franklin's disease: Ig gamma 2 H chain mutant BUR.

B. Frangione, F. Prelli, 1992, Journal of immunology.

Alzheimer's beta-amyloid vasoactivity: identification of a novel beta-amyloid conformational intermediate.

C. Soto, M. Mullan, F. Crawford, 1998, FEBS letters.

The amino acid sequence of the major coat protein subunit of the filamentous virus Xf

W. Konigsberg, B. Frangione, Y. Nakashima, 1978, FEBS letters.

Amyloid beta 1-42 deposits do not lead to Alzheimer's neuritic plaques in aged dogs.

M. Lalowski, T. Wisniewski, B. Frangione, 1996, The Biochemical journal.

Amyloid β 1 – 42 deposits do not lead to Alzheimer ’ s neuritic plaques in aged dogs

M. Lalowski, T. Wisniewski, B. Frangione, 1996 .

FAMILIAL AND SPORADIC CEREBRAL AMYLOID ANGIOPATHY

B. Frangione, 1988 .

Inhibition of Alzheimer beta-fibrillogenesis by melatonin.

B Frangione, J Ghiso, C. Soto, 1998, The Journal of biological chemistry.

Inherited Amyloidoses and Neurodegeneration: Familial British Dementia and Familial Danish Dementia

G. Plant, T. Révész, J. Holton, 2011 .

Biochemical and conformational variability of human prion strains in sporadic Creutzfeldt–Jakob disease

T. Wisniewski, B. Frangione, P. Aucouturier, 1999, Neuroscience Letters.

The amino acid sequence of neuritic plaque amyloid from a familial Alzheimer's disease patient

M. Lalowski, E. Levy, B. Frangione, 1994, Annals of neurology.

Apolipoprotein E: binding to soluble Alzheimer's beta-amyloid.

T. Wisniewski, E. Matsubara, J. Ghiso, 1993, Biochemical and biophysical research communications.

Primary structure of human plasma fibronectin. Characterization of a 38 kDa domain containing the C-terminal heparin-binding site (Hep III site) and a region of molecular heterogeneity.

A. Rostagno, B. Frangione, A. García-Pardo, 1987, The Biochemical journal.

Primary structure of human plasma fibronectin. Characterization of a 31,000-dalton fragment from the COOH-terminal region containing a free sulfhydryl group and a fibrin-binding site.

B. Frangione, A. García-Pardo, E. Pearlstein, 1985, The Journal of biological chemistry.

STRUCTURAL STUDIES OF IMMUNOGLOBULIN G, M AND A HEAVY CHAINS

B. Frangione, F. Prelli, E. Franklin, 1971, Annals of the New York Academy of Sciences.

Down syndrome as a key to the time sequence of brain changes in Alzheimer disease.

F. Tagliavini, O. Bugiani, B. Frangione, 1992, Progress in clinical and biological research.

Insulin-degrading enzyme in brain microvessels: proteolysis of amyloid (cid:69) vasculotropic variants and reduced activity in cerebral amyloid angiopathy

L. Lue, I. Mathov, J. Ghiso, 2004 .

Differential Degradation of Amyloid β Genetic Variants Associated with Hereditary Dementia or Stroke by Insulin-degrading Enzyme*

J. Ghiso, L. Morelli, R. Llovera, 2003, Journal of Biological Chemistry.

O2-03-07 Biochemical analysis of Aβ amyloid deposits in the Iowa variant of Alzheimer's disease

S. Greenberg, J. Ghiso, A. Rostagno, 2004, Neurobiology of Aging.

Multiple mutations in the variable region of the kappa light chains of three monoclonal human IgM with anti-myelin-associated glycoprotein activity.

B. Frangione, H. Ayadi, J. Brouet, 1989, Journal of Biological Chemistry.

DEGENERATION OF SMOOTH MUSCLE CELLS IN BETA-AMYLOID ANGIOPATHIES: 201

B. Frangione, F. Coria, M. Larrondo-Lillo, 1989 .

Structural studies of a human gamma 3 myeloma protein (Goe) that binds staph protein A.

B. Frangione, E. Franklin, E. van Loghem, 1981, Journal of immunology.

Repetitive hinge region sequences in human IgG3: isolation of an 11,000-dalton fragment.

B. Frangione, E. Franklin, J. B. Adlersberg, 1975, Proceedings of the National Academy of Sciences of the United States of America.

Cerebrospinal fluid inhibits Alzheimer β‐amyloid fibril formation in vitro

T. Wisniewski, J. Ghiso, B. Frangione, 1993, Annals of neurology.

Non-Alzheimer's disease amyloidoses of the nervous system.

B. Frangione, E. Castaño, 1995, Current opinion in neurology.

Protein Rou. A human IgA hybrid.

B. Frangione, M. Gendron, E. Mihaesco, 1988, Journal of Immunology.

Prion protein hereditary amyloidosis: parenchymal and vascular

B. Ghetti, M. Farlow, F. Tagliavini, 1996 .

Conformation as therapeutic target in the prionoses and other neurodegenerative conditions.

E. Sigurdsson, T. Wisniewski, B. Frangione, 2001, Methods in molecular medicine.

Disulphide Bridges of Immunoglobin G1 Heavy Chains

C. Milstein, B. Frangione, 1967, Nature.

Proteinases secreted by Fasciola hepatica degrade extracellular matrix and basement membrane components.

J. Dalton, A. Dowd, B. Frangione, 1997, The Journal of parasitology.

Interchain and intrachain disulfide bridges of a human immunoglobulin M: detection of a unique fragment.

B. Frangione, F. Prelli, E. Franklin, 1971, Proceedings of the National Academy of Sciences of the United States of America.

Chemical typing of the immunoglobulins IgM, IgA1 and IgA2

B. Frangione, E. Franklin, Blas Frangione, 1972, FEBS letters.

Iowa Variant of Familial Alzheimer’s Disease Accumulation of Posttranslationally Modified A (cid:1) D23N in Parenchymal and Cerebrovascular Amyloid Deposits

Yun Lu, S. Greenberg, J. Ghiso, 2010 .

Isolation and Partial Characterization of Alzheimer Neurofibrillary Tangles

B. Pons-Estel, B. Frangione, P. Gorevic, 1986 .

Synthetic peptides homologous to prion protein residues 106-147 form amyloid-like fibrils in vitro.

B. Ghetti, G. Forloni, F. Tagliavini, 1993, Proceedings of the National Academy of Sciences of the United States of America.

beta-Amyloid precursor protein gene in squirrel monkeys with cerebral amyloid angiopathy.

L. Walker, E. Levy, B. Frangione, 1995, Neurobiology of aging.

Inhibition of Alzheimer's beta (Aβ) amyloid fibril formation

C. Soto, J. Ghiso, B. Frangione, 1997 .

APP processing, A beta-amyloidogenesis, and the pathogenesis of Alzheimer's disease.

P. Greengard, J. Buxbaum, B. Frangione, 1994, Neurobiology of aging.

O4-01-05: Presenilin 1 mutation promotes Tau phosphorylation and aggregation in a novel Alzheimer's disease mouse model

E. Sigurdsson, T. Wisniewski, J. Brion, 2008, Alzheimer's & Dementia.

Co-existence of amyloid ADan and amyloid-beta in familial Danish dementia

T. Révész, J. Holton, H. Houlden, 2002 .

ONLY MUTANT PRP PARTICIPATES IN AMYLOID FORMATION IN GERSTMANN-STRÄUSSLER-SCHEINKER DISEASE WITH ALA>VAL SUBSTITUTION AT CODON 117: 21

B. Ghetti, T. Bird, F. Tagliavini, 1995 .

STRUCTURAL STUDIES OF HUMAN IMMUNOGLOBULINS

B. Frangione, E. Franklin, 1965, The Journal of experimental medicine.

Transthyretin gene in Alzheimer's disease patients

T. Wisniewski, J. Palha, B. Frangione, 1996, Neuroscience Letters.

Proteolytic processing of human amyloid beta protein precursor in insect cells. Major carboxyl-terminal fragment is identical to its human counterpart.

P. Greengard, A. Czernik, S. Gandy, 1993, The Journal of biological chemistry.

Major coat protein and single-stranded DNA-binding protein of filamentous virus Pf3.

A. Casadevall, B. Frangione, H. L. Yang, 1984, Proceedings of the National Academy of Sciences of the United States of America.

A decamer duplication in the BRI gene originates a de-novo amyloid peptide that causes dementia in a Danish kindred

G. Plant, T. Révész, T. Bek, 2000, Neurobiology of Aging.

Hereditary cerebral haemorrhage with amyloidosis, Dutch type (HCHWA-D): clinicopathological studies.

W. Luyendijk, B. Frangione, A. Wattendorff, 1995, Journal of neurology, neurosurgery, and psychiatry.

Studies on the Variability of Immunoglobulin Sequence

C. Milstein, B. Frangione, J. Pink, 1967 .

Distribution of the protease inhibitor alpha 1-antichymotrypsin in cerebral and systemic amyloid.

M. Picken, M. Shelanski, B. Frangione, 1990, Journal of neuropathology and experimental neurology.

Chemical typing of immunoglobulins and their subtypes.

B. Frangione, S. Kochwa, E. Makuku, 1975, Archives of internal medicine.

Structure of immunoglobulin A. I. Interchain disulfide bridges of a A1 myeloma protein.

B. Frangione, E. Franklin, E. Mihaesco, 1971, Biochemistry.

Diversity of senile plaques in Alzheimer's disease as revealed by a new monoclonal antibody that recognizes an internal sequence of the Abeta peptide.

J. Ghiso, M. Calero, E. Méndez, 2005, Current Alzheimer research.

Immunoglobulin A. Arrangement of disulfide bridges in the "hinge" region of an immunoglobulin lin A-1 human myeloma protein.

B. Frangione, F. Prelli, E. Franklin, 1973, Biochemistry.