H. Naiki

发表

Direct Observation of Aβ Amyloid Fibril Growth and Inhibition

Satoshi Takahashi, M. Hoshino, T. Ban, 2004 .

Cross-seeding and cross-competition in mouse apolipoprotein A-II amyloid fibrils and protein A amyloid fibrils.

Junjie Yao, Keiichi Higuchi, Masayuki Mori, 2007, The American journal of pathology.

Apolipoprotein A-II gene and development of amyloidosis and senescence in a congenic strain of mice carrying amyloidogenic ApoA-II.

K. Kitagawa, T. Matsushita, K. Higuchi, 1995, Laboratory investigation; a journal of technical methods and pathology.

Cerebral amyloid angiopathy.

M. Yamada, H. Naiki, 2012, Progress in molecular biology and translational science.

Curcumin has potent anti‐amyloidogenic effects for Alzheimer's β‐amyloid fibrils in vitro

Kenjiro Ono, Masahito Yamada, Hironobu Naiki, 2004, Journal of neuroscience research.

Multiple inflammatory cytokine‐productive ThyL‐6 cell line established from a patient with thymic carcinoma

Y. Imamura, H. Naiki, T. Ueda, 2008, Cancer science.

ras Gene mutations and hpv infection are common in human laryngeal carcinoma

H. Naiki, K. Nakakuki, M. Inuzuka, 1993, International journal of cancer.

A toxic monomeric conformer of the polyglutamine protein

Y. Urade, T. Toda, K. Hasegawa, 2007, Nature Structural &Molecular Biology.

The features of bone articular lesions in dialysis-related amyloidosis (DRA) and criteria for the clinical diagnosis of DRA

S. Nishi, H. Naiki, Suguru Yamamoto, 2019, Renal Replacement Therapy.

αB-crystallin, a small heat-shock protein, prevents the amyloid fibril growth of an amyloid β-peptide and β2-microglobulin

T. Ban, H. Naiki, Y. Goto, 2005 .

Kinetic analysis of the polymerization and depolymerization of beta(2)-microglobulin-related amyloid fibrils in vitro.

F. Gejyo, K. Hasegawa, H. Naiki, 2005, Biochimica et biophysica acta.

Molecular interactions in the formation and deposition of β2-microglobulin-related amyloid fibrils

F. Gejyo, K. Hasegawa, H. Naiki, 2005, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Acceleration of chromosome aberrations in senescence-accelerated strains of mice.

M. Sasaki, K. Yasuoka, M. Hosokawa, 1990, Mutation research.

Fluorometric examination of tissue amyloid fibrils in murine senile amyloidosis: use of the fluorescent indicator, thioflavine T.

K. Matsushima, M. Hosokawa, A. Shimada, 1990, Laboratory investigation; a journal of technical methods and pathology.

Establishment of a kinetic model of dialysis-related amyloid fibril extension in vitro

Satoru Suzuki, F. Gejyo, H. Naiki, 1997 .

Kinetic Properties of Amyloid Fibril Polymerization in Vitro

K. Higuchi, H. Naiki, T. Takeda, 1991 .

Structural studies reveal that the diverse morphology of beta(2)-microglobulin aggregates is a reflection of different molecular architectures.

P. Závodszky, J. Kardos, T. Kitagawa, 2005, Biochimica et biophysica acta.

The Development of Preventives and Therapeutics for Alzheimers Disease that Inhibit the Formation of β-Amyloid Fibrils (fAβ), as Well as Destabilize Preformed fAβ

K. Ono, M. Yamada, H. Naiki, 2006 .

HBME‐1 and CD15 immunocytochemistry in the follicular variant of thyroid papillary carcinoma

Y. Imamura, H. Naiki, M. Ohta, 2015, Pathology international.

A Seed for Alzheimer Amyloid in the Brain

D. Selkoe, C. Lemere, H. Hayashi, 2004, The Journal of Neuroscience.

Amyloidogenic synthetic peptides of beta2-microglobulin--a role of the disulfide bond.

Yuji Goto, Shinobu Tsutsumi, Hironobu Naiki, 2003, Biochemical and biophysical research communications.

Kinetic analysis of amyloid fibril polymerization in vitro.

K. Higuchi, H. Naiki, T. Takeda, 1991, Laboratory investigation; a journal of technical methods and pathology.

The intrachain disulfide bond of beta(2)-microglobulin is not essential for the immunoglobulin fold at neutral pH, but is essential for amyloid fibril formation at acidic pH.

M. Hoshino, K. Hasegawa, H. Naiki, 2002, Journal of biochemistry.

Critical role of interfaces and agitation on the nucleation of Abeta amyloid fibrils at low concentrations of Abeta monomers.

A. Morinaga, M. Yamada, K. Hasegawa, 2010, Biochimica et biophysica acta.

Kinetic analysis of amyloid fibril formation.

F. Gejyo, H. Naiki, 1999, Methods in enzymology.

Environment‐ and mutation‐dependent aggregation behavior of Alzheimer amyloid β‐protein

Naoki Yamamoto, K. Yanagisawa, K. Matsuzaki, 2004, Journal of neurochemistry.

Potent anti‐amyloidogenic and fibril‐destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease

A. Takashima, K. Ono, M. Yamada, 2003, Journal of neurochemistry.

Nordihydroguaiaretic acid potently breaks down pre‐formed Alzheimer's β‐amyloid fibrils in vitro

A. Takashima, K. Ono, M. Yamada, 2002, Journal of neurochemistry.

Intra-tumoral distribution of (64)Cu-ATSM: a comparison study with FDG.

Y. Yonekura, K. Kashikura, Y. Fujibayashi, 2003, Nuclear medicine and biology.

Pathological examination of cerebral amyloid angiopathy in patients who underwent removal of lobar hemorrhages

H. Arai, R. Kitai, K. Kikuta, 2018, Journal of Neurology.

Expression of proliferating cell nuclear antigen and CD44 variant isoforms in the primary and metastatic sites of nonsmall cell lung carcinoma with intrapulmonary metastases

H. Wada, H. Naiki, T. Fukuse, 1999, Cancer.

Expression of E-cadherin and lymph node metastasis in resected non-small-cell lung cancer.

H. Naiki, T. Fukuse, T. Hirata, 2001, Clinical lung cancer.

Expression of CD44 variant exon 6 in stage I non-small cell lung carcinoma as a prognostic factor.

H. Naiki, T. Fukuse, T. Hirata, 1998, Cancer research.

Prognostic significance of proliferative activity in pN2 non-small-cell lung carcinomas and their mediastinal lymph node metastases.

H. Naiki, T. Fukuse, T. Hirata, 2000, Annals of surgery.

Remnant lipoprotein particles are taken up into myocardium through VLDL receptor--a possible mechanism for cardiac fatty acid metabolism.

Kazuya Yamada, I. Miyamori, H. Hattori, 2002, Biochemical and biophysical research communications.

Helicobacter pylori CagA Containing ITAM‐Like Sequences Localized to Lipid Rafts Negatively Regulates VacA‐Induced Signaling In Vivo

M. Noda, K. Tsujikawa, K. Sada, 2003, Helicobacter.

Azithromycin Reduces Tumor Necrosis Factor-Alpha Production in Lipopolysaccharide-Stimulated THP-1 Monocytic Cells by Modification of Stress Response and p38 MAPK Pathway

H. Iwasaki, H. Naiki, T. Ueda, 2009, Journal of chemotherapy.

Preformed beta-amyloid fibrils are destabilized by coenzyme Q10 in vitro.

K. Ono, M. Yamada, K. Hasegawa, 2005, Biochemical and biophysical research communications.

Preformed β-amyloid fibrils are destabilized by coenzyme Q10 in vitro

K. Ono, M. Yamada, K. Hasegawa, 2005 .

Anti-amyloidogenic activity of tannic acid and its activity to destabilize Alzheimer's beta-amyloid fibrils in vitro.

K. Ono, M. Yamada, K. Hasegawa, 2004, Biochimica et biophysica acta.

Deficiency of the very low-density lipoprotein (VLDL) receptors in streptozotocin-induced diabetic rats: insulin dependency of the VLDL receptor.

M. Nagano, I. Miyamori, H. Hattori, 2005, Endocrinology.

Mouse senile amyloidosis

K. Kitagawa, M. Hosokawa, K. Higuchi, 1991, Virchows Archiv. B, Cell pathology including molecular pathology.

Tissue distribution, biochemical properties, and transmission of mouse type A AApoAII amyloid fibrils.

M. Ueno, M. Hosokawa, T. Ishihara, 2004, The American journal of pathology.

Pathology International

K. Ohashi, M. Shimoda, Y. Ando, 2020 .

Metabolism of senile amyloid precursor and amyloidogenesis. Age-related acceleration of apolipoprotein A-II clearance in the senescence accelerated mouse.

M. Hosokawa, K. Higuchi, H. Naiki, 1988, The American journal of pathology.

The monomer-seed interaction mechanism in the formation of the β2-microglobulin amyloid fibril clarified by solution NMR techniques.

T. Ikegami, K. Sugase, T. Konuma, 2012, Journal of molecular biology.

Antigen-primed splenic CD8+ T cells impede the development of oral antigen-induced allergic diarrhea.

H. Naiki, A. Yamada, M. Mayumi, 2009, The Journal of allergy and clinical immunology.

Reactivation of HSV‐1 in the brain of patients with familial Alzheimer's disease

I. Mori, T. Yokochi, Y. Nishiyama, 2004, Journal of medical virology.

Chronic hypoxia exacerbates diabetic glomerulosclerosis through mesangiolysis and podocyte injury in db/db mice.

H. Naiki, M. Iwano, M. Hara, 2020, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Over‐expression of p53 protein in human laryngeal carcinoma

H. Naiki, K. Nakakuki, M. Inuzuka, 2009, International journal of cancer.

High frequency of human papillomavirus infection in carcinoma of the urinary bladder

H. Naiki, K. Nakakuki, M. Inuzuka, 1992, Cancer.

Accelerated senile amyloidosis induced by amyloidogenic Apoa-II gene shortens the life span of mice but does not accelerate the rate of senescence.

K. Kitagawa, M. Hosokawa, T. Matsushita, 1996, The journals of gerontology. Series A, Biological sciences and medical sciences.

Amyloid fibril formation of the mouse V(L) domain at acidic pH.

A. Dubnovitsky, M. Hoshino, K. Hasegawa, 2002, Biochemistry.

ThT 101: a primer on the use of thioflavin T to investigate amyloid formation

D. Otzen, J. Buchner, M. Ramirez-Alvarado, 2017, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Lysophospholipids induce the nucleation and extension of beta2-microglobulin-related amyloid fibrils at a neutral pH.

K. Hasegawa, H. Naiki, Y. Goto, 2008, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Apolipoprotein E and antioxidants have different mechanisms of inhibiting Alzheimer's beta-amyloid fibril formation in vitro.

F. Gejyo, K. Hasegawa, H. Naiki, 1998, Biochemistry.

Secondary malignant fibrous histiocytoma following refractory langerhans cell histiocytosis.

H. Baba, H. Arai, T. Yamauchi, 2009, Journal of clinical and experimental hematopathology : JCEH.

Elevated Levels of Urinary Extracellular Vesicle Fibroblast-Specific Protein 1 in Patients with Active Crescentic Glomerulonephritis

H. Naiki, M. Iwano, M. Hara, 2018, Nephron.

Frequent Detection of Multidrug-Resistant Pneumonia-Causing Bacteria in the Pneumonia Lung Tissues of Patients with Hematological Malignancies

H. Iwasaki, Y. Imamura, H. Naiki, 2007, International journal of hematology.

An autopsy case of disseminated mucormycosis in a neutropenic patient receiving chemotherapy for the underlying solid malignancy

H. Arai, H. Iwasaki, T. Yamauchi, 2002, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Vitamin A exhibits potent antiamyloidogenic and fibril-destabilizing effects in vitro

A. Takashima, K. Ono, M. Yamada, 2004, Experimental Neurology.

Successful protection by amantadine hydrochloride against lethal encephalitis caused by a highly neurovirulent recombinant influenza A virus in mice.

I. Mori, T. Yokochi, T. Daikoku, 2002, Virology.

Interaction between A beta(1-42) and A beta(1-40) in Alzheimer's beta-amyloid fibril formation in vitro.

F. Gejyo, K. Hasegawa, H. Naiki, 1999, Biochemistry.

Pathological review of cardiac amyloidosis using autopsy cases in a single Japanese institution.

T. Ninomiya, Y. Oda, Hidetaka Yamamoto, 2021, Pathology, research and practice.

Distinguishing crystal-like amyloid fibrils and glass-like amorphous aggregates from their kinetics of formation

Hirotsugu Ogi, Young-Ho Lee, Hiroki Kitayama, 2012, Proceedings of the National Academy of Sciences.

Possible mechanisms of polyphosphate-induced amyloid fibril formation of β2-microglobulin

I. Narita, J. Kardos, H. Naiki, 2019, Proceedings of the National Academy of Sciences.

2P075 Ultrasonication-induced amyloid fibril formation of beta_2-microglobulin

H. Naiki, Y. Goto, Y. Ohhashi, 2005 .

Investigation of a Peptide Responsible for Amyloid Fibril Formation of β2-Microglobulin byAchromobacter Protease I*

Yoshihisa Hagihara, Yuji Goto, Hironobu Naiki, 2002, The Journal of Biological Chemistry.

Direct Measurement of the Thermodynamic Parameters of Amyloid Formation by Isothermal Titration Calorimetry*

Yuji Goto, József Kardos, Hironobu Naiki, 2004, Journal of Biological Chemistry.

Conformational stability of amyloid fibrils of β2‐microglobulin probed by guanidine‐hydrochloride‐induced unfolding

Kazumasa Sakurai, Yuji Goto, Masaru Hoshino, 2004, FEBS letters.

Dissolution of beta2-microglobulin amyloid fibrils by dimethylsulfoxide.

K. Hasegawa, H. Naiki, Y. Goto, 2003, Journal of biochemistry.

Kinetically controlled thermal response of beta2-microglobulin amyloid fibrils.

Yuji Goto, Hironobu Naiki, H. Naiki, 2005, Journal of Molecular Biology.

Abdominal Fat Pad Fine-Needle Aspiration for Diagnosis of Cardiac Amyloidosis in Patients with Non-Ischemic Cardiomyopathy.

H. Tada, H. Naiki, Y. Sekijima, 2022, International heart journal.

Procollagen C-proteinase enhancer-1 (PCPE-1) interacts with beta2-microglobulin (beta2-m) and may help initiate beta2-m amyloid fibril formation in connective tissues.

J. Mott, H. Makino, B. Font, 2008, Matrix biology : journal of the International Society for Matrix Biology.

3D Structure of amyloid protofibrils of beta2-microglobulin fragment probed bysolid-state NMR

K. Iwata, Satoshi Takahashi, T. Fujiwara, 2006 .

Stereospecific amyloid-like fibril formation by a peptide fragment of beta2-microglobulin.

Satoshi Takahashi, T. Kawai, H. Naiki, 2005, Biochemistry.

Seeding-dependent Maturation of β2-Microglobulin Amyloid Fibrils at Neutral pH*

K. Hasegawa, H. Naiki, Y. Goto, 2005, Journal of Biological Chemistry.

Amyloid nucleation triggered by agitation of beta2-microglobulin under acidic and neutral pH conditions.

H. Naiki, Y. Goto, K. Sasahara, 2008, Biochemistry.

Thioflavin T: not an all-rounder, but a trustworthy friend for over 27 years

H. Naiki, 2017, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Direct observation of Abeta amyloid fibril growth and inhibition.

Satoshi Takahashi, M. Hoshino, T. Ban, 2004, Journal of molecular biology.

Differentiation induction in non-lymphocytic leukemia cells upon treatment with mycophenolate mofetil.

H. Iwasaki, T. Yamauchi, H. Naiki, 2000, Leukemia research.

3. Other Secondary Nephrotic Syndrome

H. Naiki, K. Kasuno, H. Kimura, 2009 .

Serum Clearance Rate of Senile Amyloid Related Apolipoprotein A-II is Accelerated with Increasing Age in Senescence Accelerated Mouse (SAM)

M. Hosokawa, K. Higuchi, H. Naiki, 1988 .

Y. Fujibayashi, J. Kimura, M. Ueno, 1993, Archives of gerontology and geriatrics.

Autopsy case with concurrent transthyretin and immunoglobulin amyloidosis

Yukako Shintani-Domoto, H. Naiki, T. Sakatani, 2021, Pathology international.

Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1.

M. Hosokawa, K. Higuchi, H. Naiki, 1989, Analytical biochemistry.

Real-time and single fibril observation of the formation of amyloid beta spherulitic structures.

S. Yuba, T. Kawasaki, T. Ban, 2006, The Journal of biological chemistry.

AlphaB-crystallin, a small heat-shock protein, prevents the amyloid fibril growth of an amyloid beta-peptide and beta2-microglobulin.

T. Ban, H. Naiki, Y. Goto, 2005, The Biochemical journal.

The persistence of high uptake of serum albumin in the olfactory bulbs of mice throughout their adult lives.

H. Fukuyama, Y. Fujibayashi, J. Kimura, 1991, Archives of gerontology and geriatrics (Print).

Clinical, pathological, and proteomic characteristics of newly diagnosed amyloidosis patients: Experience from a single referral center in Japan

Y. Ando, H. Naiki, M. Ueda, 2020, Neurology and Clinical Neuroscience.

Severe intraglomerular detachment of podocytes in a Gitelman syndrome patient

M. Yasujima, H. Naiki, M. Iwano, 2012, Clinical and Experimental Nephrology.

Anionic contribution for fibrous maturation of protofibrillar assemblies of the human tau repeat domain in a fluoroalcohol solution.

S. Oiki, T. Konno, K. Hasegawa, 2004, Biochemistry.

Visualization and classification of amyloid beta supramolecular assemblies.

T. Ban, H. Naiki, Y. Goto, 2007, Biochemistry.

Glycosaminoglycan and proteoglycan inhibit the depolymerization of beta2-microglobulin amyloid fibrils in vitro.

F. Gejyo, K. Hasegawa, H. Naiki, 2003, Kidney international.

Class I small leucine-rich proteoglycans (SLRPs) colocalise with the Aβ2M amyloid deposits: implications for the roles of SLRP core proteins in the pathogenesis of dialysis-related amyloidosis

Y. Kokubo, A. Matsumine, Y. Ando, 2019, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Glycosaminoglycans enhance the trifluoroethanol-induced extension of beta 2-microglobulin-related amyloid fibrils at a neutral pH.

F. Gejyo, K. Hasegawa, H. Naiki, 2004, Journal of the American Society of Nephrology : JASN.

Ultrasonication-dependent production and breakdown lead to minimum-sized amyloid fibrils

H. Naiki, Y. Goto, Young-Ho Lee, 2009, Proceedings of the National Academy of Sciences.

Heat-induced conversion of beta(2)-microglobulin and hen egg-white lysozyme into amyloid fibrils.

H. Naiki, Y. Goto, K. Sasahara, 2008, Journal of molecular biology.

Apolipoprotein E inhibits the depolymerization of beta 2-microglobulin-related amyloid fibrils at a neutral pH.

F. Gejyo, K. Hasegawa, H. Naiki, 2001, Biochemistry.

Recent progress in understanding dialysis-related amyloidosis.

I. Narita, F. Gejyo, H. Naiki, 2009, Bone.

MR of pituitary metastasis in a patient with diabetes insipidus.

Y. Ishii, M. Maeda, H. Naiki, 1995, AJNR. American journal of neuroradiology.

Anti-amyloidogenic effects of antioxidants: implications for the prevention and therapeutics of Alzheimer's disease.

Tsuyoshi Hamaguchi, Kenjiro Ono, Masahito Yamada, 2006, Biochimica et biophysica acta.

Frequent Detection of Multidrug-Resistant Pneumonia-Causing Bacteria in the Pneumonia Lung Tissues of Patients with Hematological Malignancies

H. Iwasaki, Y. Imamura, H. Naiki, 2007, International journal of hematology.

Mouse model to study human A β2M amyloidosis: generation of a transgenic mouse with excessive expression of human β2-microglobulin

Y. Ando, Xiaoying Fu, K. Higuchi, 2010, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

The anti-amyloidogenic effect is exerted against Alzheimer's beta-amyloid fibrils in vitro by preferential and reversible binding of flavonoids to the amyloid fibril structure.

Kenjiro Ono, Masahito Yamada, Hironobu Naiki, 2007, Biochemistry.

Mechanism by which the amyloid-like fibrils of a beta 2-microglobulin fragment are induced by fluorine-substituted alcohols.

H. Naiki, Y. Goto, Kei-ichi Yamaguchi, 2006, Journal of molecular biology.

Immune abnormality in relation to nonimmune diseases in sam mice

K. Higuchi, H. Naiki, T. Hosokawa, 1997, Experimental Gerontology.

Effects of dietary restriction on age-related immune dysfunction in the senescence accelerated mouse (SAM).

M. Hosokawa, H. Naiki, M. Umezawa, 1990, The Journal of nutrition.

Molecular Pathogenesis Genetic Inherited Diseases Transmission of Amyloidosis in Offspring of Mice with AApoAII Amyloidosis

M. Hosokawa, T. Matsushita, Xiaoying Fu, 2006 .

A molecular-pathologic approach to murine senile amyloidosis. Serum precursor-apolipoprotein A-II variant (Pro5----Gln) presents only in the senile amyloidosis-prone SAM-P/1 and SAM-P/2 mice.

K. Higuchi, H. Naiki, S. Tsunasawa, 1987, Laboratory investigation; a journal of technical methods and pathology.

[Search for antiamyloidogenic compounds based on a nucleation-dependent polymerization model].

K. Ono, M. Yamada, K. Hasegawa, 2010, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Nuclear magnetic resonance characterization of the refolding intermediate of beta2-microglobulin trapped by non-native prolyl peptide bond.

A. Kameda, Satoshi Takahashi, M. Hoshino, 2005, Journal of molecular biology.

Supersaturation-Limited and Unlimited Phase Spaces Compete to Produce Maximal Amyloid Fibrillation near the Critical Micelle Concentration of Sodium Dodecyl Sulfate.

H. Naiki, Y. Goto, M. So, 2015, Langmuir : the ACS journal of surfaces and colloids.

Development of congenic strains of mice carrying amyloidogenic apolipoprotein A‐II (Apoa2c)

K. Kitagawa, K. Higuchi, H. Naiki, 1993, FEBS letters.

Conformational dynamics of beta(2)-microglobulin analyzed by reduction and reoxidation of the disulfide bond.

M. Hoshino, H. Naiki, Y. Goto, 2003, Journal of biochemistry.

Cytology of Pleural Effusion Associated with Disseminated Infection Caused by Varicella-Zoster Virus in an Immunocompromised Patient

M. Fukuda, Y. Imamura, Masaki Mori, 2003, Acta Cytologica.

Genetic analysis of murine senile amyloidosis.

A. Shimada, K. Higuchi, H. Naiki, 1993, Laboratory investigation; a journal of technical methods and pathology.

Polymorphism of apolipoprotein A-II (apoA-II) among inbred strains of mice. Relationship between the molecular type of apoA-II and mouse senile amyloidosis.

K. Kitagawa, M. Hosokawa, K. Higuchi, 1991, The Biochemical journal.

Amyloid fibrils formed by selective N- and C-terminal sequences of mouse apolipoprotein A-II

F. Kametani, K. Higuchi, K. Hasegawa, 2011, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Amyloid fibrils formed by selective N-, C-terminal sequences of mouse apolipoprotein A-II.

F. Kametani, K. Higuchi, K. Hasegawa, 2009, Biochimica et Biophysica Acta.

Molecular Genetic Study of Mouse Senile Amyloidosis

K. Kitagawa, M. Hosokawa, K. Higuchi, 1991 .

C-terminal sequence of amyloid-resistant type F apolipoprotein A-II inhibits amyloid fibril formation of apolipoprotein A-II in mice

F. Kametani, K. Higuchi, K. Hasegawa, 2015, Proceedings of the National Academy of Sciences.

Prognostic significance of cyclin E overexpression in resected non-small cell lung cancer.

H. Naiki, T. Fukuse, T. Hirata, 2000, Cancer research.

Iron (III) induces aggregation of hyperphosphorylated τ and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease

Hironobu Naiki, R. Shin, K. Hasegawa, 2002 .

Tubulointerstitial Nephritis with IgM-Positive Plasma Cells.

I. Narita, K. Sada, C. Munemura, 2017, Journal of the American Society of Nephrology : JASN.

Correction: Endocytosed β2-Microglobulin Amyloid Fibrils Induce Necrosis and Apoptosis of Rabbit Synovial Fibroblasts by Disrupting Endosomal/Lysosomal Membranes: A Novel Mechanism on the Cytotoxicity of Amyloid Fibrils

K. Hasegawa, H. Naiki, R. Khodarahmi, 2015, PloS one.

Endocytosed β2-Microglobulin Amyloid Fibrils Induce Necrosis and Apoptosis of Rabbit Synovial Fibroblasts by Disrupting Endosomal/Lysosomal Membranes: A Novel Mechanism on the Cytotoxicity of Amyloid Fibrils

K. Hasegawa, H. Naiki, I. Yamaguchi, 2015, PloS one.

Fanconi syndrome in an elderly patient with membranous nephropathy during treatment with the immunosuppressant mizoribine

H. Naiki, M. Iwano, K. Kasuno, 2022, CEN Case Reports.

Immunotherapy with oligomannose‐coated liposomes ameliorates allergic symptoms in a murine food allergy model

H. Naiki, M. Mayumi, Y. Ohshima, 2012, Allergy.

Macromolecular crowding and supersaturation protect hemodialysis patients from the onset of dialysis-related amyloidosis

I. Narita, H. Ogi, K. Ikenaka, 2022, bioRxiv.

Amyloid formation under complicated conditions in which β2-microglobulin coexists with its proteolytic fragments.

J. Kardos, H. Naiki, Y. Goto, 2019, Biochemistry.

Heating during agitation of β2-microglobulin reveals that supersaturation breakdown is required for amyloid fibril formation at neutral pH

J. Kardos, H. Naiki, Y. Goto, 2019, The Journal of Biological Chemistry.

Thiol compounds inhibit the formation of amyloid fibrils by beta 2-microglobulin at neutral pH.

H. Naiki, Y. Goto, K. Sasahara, 2008, Journal of molecular biology.

Core and heterogeneity of beta2-microglobulin amyloid fibrils as revealed by H/D exchange.

M. Hoshino, K. Hasegawa, H. Naiki, 2004, Journal of molecular biology.

Conformation of β2-Microglobulin Amyloid Fibrils Analyzed by Reduction of the Disulfide Bond*

K. Hasegawa, H. Naiki, Y. Goto, 2002, The Journal of Biological Chemistry.

Growth of beta(2)-microglobulin-related amyloid fibrils by non-esterified fatty acids at a neutral pH.

K. Hasegawa, H. Naiki, Y. Goto, 2008, The Biochemical journal.

Low concentrations of sodium dodecyl sulfate induce the extension of beta 2-microglobulin-related amyloid fibrils at a neutral pH.

Suguru Yamamoto, Yuji Goto, József Kardos, 2004, Biochemistry.

Surface-bound basement membrane components accelerate amyloid-β peptide nucleation in air-free wells: an in vitro model of cerebral amyloid angiopathy.

K. Hasegawa, H. Naiki, T. Ookoshi, 2013, Biochimica et biophysica acta.

A Comprehensive Model for Packing and Hydration for Amyloid Fibrils of β2-Microglobulin*

H. Naiki, Y. Goto, Young-Ho Lee, 2009, Journal of Biological Chemistry.

Kinetic coupling of folding and prolyl isomerization of beta2-microglobulin studied by mutational analysis.

A. Kameda, H. Naiki, Y. Goto, 2008, Journal of molecular biology.

Main-chain dominated amyloid structures demonstrated by the effect of high pressure.

M. Kato, T. Kawai, H. Naiki, 2005, Journal of molecular biology.

Amyloid Fibril Formation in the Context of Full-length Protein

K. Hasegawa, H. Naiki, Y. Goto, 2003, Journal of Biological Chemistry.

Mapping the core of the β2-microglobulin amyloid fibril by H/D exchange

M. Hoshino, K. Hasegawa, H. Naiki, 2002, Nature Structural Biology.

Aggregation-phase diagrams of β2-microglobulin reveal temperature and salt effects on competitive formation of amyloids versus amorphous aggregates

J. Kardos, H. Naiki, Y. Goto, 2018, The Journal of Biological Chemistry.

Conformation of Amyloid Fibrils of β2-Microglobulin Probed by Tryptophan Mutagenesis*

K. Iwata, A. Nakagawa, H. Naiki, 2006, Journal of Biological Chemistry.

Ultrasonication-induced Amyloid Fibril Formation of β2-Microglobulin*

H. Naiki, Y. Goto, Y. Ohhashi, 2005, Journal of Biological Chemistry.

Polymorphism of β2-Microglobulin Amyloid Fibrils Manifested by Ultrasonication-enhanced Fibril Formation in Trifluoroethanol*

H. Naiki, Y. Goto, H. Yagi, 2012, The Journal of Biological Chemistry.

Seeding-dependent propagation and maturation of amyloid fibril conformation.

Satoshi Takahashi, T. Kawai, H. Naiki, 2005, Journal of molecular biology.

Endothelin‐1‐endothelin receptor type A mediates closure of rat ductus arteriosus at birth

M. Hollenberg, H. Naiki, T. Taniguchi, 2001, The Journal of physiology.

Presence of ras oncogene mutations and human papillomavirus DNA in human prostate carcinomas.

H. Naiki, T. Shiraishi, R. Yatani, 1992, Cancer research.

Metastatic Tumor Thrombus Attached to a Pacemaker Electrode

H. Tada, H. Naiki, K. Nakakuki, 1998, Pacing and clinical electrophysiology : PACE.

Multifaceted anti-amyloidogenic and pro-amyloidogenic effects of C-reactive protein and serum amyloid P component in vitro

K. Hasegawa, H. Naiki, V. Bellotti, 2016, Scientific Reports.

Ultrasonication-dependent acceleration of amyloid fibril formation.

H. Ogi, H. Naiki, Y. Goto, 2011, Journal of molecular biology.

Seeding-dependent propagation and maturation of beta2-microglobulin amyloid fibrils under high pressure.

H. Naiki, Y. Goto, E. Chatani, 2006, Journal of molecular biology.

Title : Immunotherapy with oligomannose-coated liposomes ameliorates allergic 2 symptoms in a murine food allergy model . 3 4 Short title : Immunotherapy with oligomannose-coated liposomes

H. Naiki, Y. Ohshima, M. Yasutomi, 2012 .

Spontaneous loss-of-function mutations of the 8-oxoguanine DNA glycosylase gene in mice and exploration of the possible implication of the gene in senescence.

S. Toyokuni, M. Hosokawa, S. Kondo, 2001, Free radical biology & medicine.

Mapping the core of the beta(2)-microglobulin amyloid fibril by H/D exchange.

M. Hoshino, K. Hasegawa, H. Naiki, 2002, Nature structural biology.

Utility of postmortem imaging system for anatomical education in skull base surgery

R. Kitai, K. Kikuta, H. Naiki, 2014, Neurosurgical review.

Direct Observation of Amyloid Fibril Growth Monitored by Thioflavin T Fluorescence* 210

T. Ban, D. Hamada, K. Hasegawa, 2003, The Journal of Biological Chemistry.

Postmortem CT is more accurate than clinical diagnosis for identifying the immediate cause of death in hospitalized patients: a prospective autopsy-based study

H. Iwasaki, H. Kimura, H. Naiki, 2016, Virchows Archiv.

Increase in the conformational flexibility of β2‐microglobulin upon copper binding: A possible role for copper in dialysis‐related amyloidosis

J. Kardos, M. Hoshino, K. Hasegawa, 2004, Protein science : a publication of the Protein Society.

Cerebrospinal fluid of Alzheimer patients promotes β-amyloid fibril formation in vitro

K. Ono, D. Yanase, K. Iwasa, 2005, Neurobiology of Disease.

Cholesterol-dependent Generation of a Seeding Amyloid β-Protein in Cell Culture*

C. Haass, M. Michikawa, K. Yanagisawa, 1999, The Journal of Biological Chemistry.

Unique clinicopathological features and PrP profiles in the first autopsied case of dura mater graft-associated Creutzfeldt–Jakob disease with codon 219 lysine allele observed in Japanese population

N. Miyashita, H. Naiki, T. Kitamoto, 2009, Journal of the Neurological Sciences.

Significant association of cadaveric dura mater grafting with subpial Aβ deposition and meningeal amyloid angiopathy

A. Kakita, Hitoshi Takahashi, H. Mizusawa, 2016, Acta Neuropathologica.

Heat-induced Conversion of β2-Microglobulin and Hen Egg-white Lysozyme into Amyloid Fibrils

H. Naiki, Y. Goto, K. Sasahara, 2007 .

Reversible heat-induced dissociation of β2-microglobulin amyloid fibrils.

J. Kovács, L. Gráf, J. Kardos, 2011, Biochemistry.

Gastrointestinal AA amyloidosis secondary to chronic pyelonephritis presenting with refractory diarrhea and severe hypoalbuminemia

M. Ohtani, Y. Imamura, H. Naiki, 2021, Clinical Journal of Gastroenterology.

Development of Myeloperoxidase Anti-neutrophil Cytoplasmic Antibody-positive Necrotizing Crescentic Glomerulonephritis in an Elderly Patient with Immunological Kidney Disease

H. Naiki, M. Iwano, Naoki Takahashi, 2021, Internal medicine.

Methods in laboratory investigation : fluroremetric examination of tissue amyloid fibrils in murine senile amyloidosis : use of the fluorescent indicator, thioflavine T

Keiichi Higuchi, Hironobu Naiki, A. Shimada, 1990 .

Non-steroidal anti-inflammatory drugs have anti-amyloidogenic effects for Alzheimer's β-amyloid fibrils in vitro

K. Ono, M. Yamada, H. Naiki, 2005, Neuropharmacology.

Modification of beta 2-microglobulin with D-glucose or 3-deoxyglucosone inhibits A beta 2M amyloid fibril extension in vitro.

F. Gejyo, H. Naiki, N. Hashimoto, 1999, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

PCR Search for the Herpes Simplex Virus Type 1 Genome in Brain Sections of Patients with Familial Alzheimer's Disease

N. Koide, I. Mori, Tomoaki Yoshida, 2004, Journal of Clinical Microbiology.

Risk factor analysis for bone marrow histiocytic hyperplasia with hemophagocytosis: an autopsy study

H. Iwasaki, H. Naiki, K. Inai, 2014, Virchows Archiv.

Inhibitors of amyloid beta-protein aggregation mediated by GM1-containing raft-like membranes.

Masaki Wakabayashi, Takuma Okada, Masaru Hoshino, 2007, Biochimica et biophysica acta.

Molecular pathogenesis of protein misfolding diseases: pathological molecular environments versus quality control systems against misfolded proteins.

Yoshitaka Nagai, Hironobu Naiki, H. Naiki, 2009, Journal of biochemistry.

Critical balance of electrostatic and hydrophobic interactions is required for beta 2-microglobulin amyloid fibril growth and stability.

T. Ban, K. Hasegawa, H. Naiki, 2005, Biochemistry.

Mechanism of lysophosphatidic acid-induced amyloid fibril formation of beta(2)-microglobulin in vitro under physiological conditions.

J. Kovács, L. Gráf, E. Kovács, 2009, Biochemistry.

Association of thin filaments into thick filaments revealing the structural hierarchy of amyloid fibrils.

T. Kawai, H. Naiki, Y. Goto, 2005, Journal of structural biology.

The role of disulfide bond in the amyloidogenic state of β2‐microglobulin studied by heteronuclear NMR

T. Kawai, M. Hoshino, Hiroyuki Tanaka, 2002, Protein science : a publication of the Protein Society.

Extension of Aβ2M amyloid fibrils with recombinant human β2-microglobulin

F. Gejyo, K. Hasegawa, H. Naiki, 2001 .

First-order kinetic model of Alzheimer's beta-amyloid fibril extension in vitro.

H. Naiki, H Naiki, K Nakakuki, 1996, Laboratory investigation; a journal of technical methods and pathology.

Nicotine breaks down preformed Alzheimer’s β-amyloid fibrils in vitro

Kenjiro Ono, Masahito Yamada, Hironobu Naiki, 2002, Biological Psychiatry.

Nicotine breaks down preformed Alzheimer's beta-amyloid fibrils in vitro.

Kenjiro Ono, Masahito Yamada, Hironobu Naiki, 2002, Biological psychiatry.

Skin inflammation exacerbates food allergy symptoms in epicutaneously sensitized mice

A. Kawasaki, H. Naiki, Y. Ohshima, 2018, Allergy.

Feasibility of liver weight estimation by postmortem computed tomography images: An autopsy study

H. Kimura, H. Naiki, K. Inai, 2014, Pathology international.

Heat of supersaturation-limited amyloid burst directly monitored by isothermal titration calorimetry

T. Ikegami, J. Kardos, H. Naiki, 2014, Proceedings of the National Academy of Sciences.

Induction of AApoAII amyloidosis by various heterogeneous amyloid fibrils

S. Ikeda, M. Hosokawa, T. Matsushita, 2004, FEBS letters.

Establishment of a first-order kinetic model of light chain-associated amyloid fibril extension in vitro.

F. Gejyo, K. Hasegawa, H. Naiki, 2002, Biochimica et biophysica acta.

Anti-Parkinsonian agents have anti-amyloidogenic activity for Alzheimer's β-amyloid fibrils in vitro

K. Ono, M. Yamada, K. Hasegawa, 2006, Neurochemistry International.

Direct observation of minimum‐sized amyloid fibrils using solution NMR spectroscopy

T. Ikegami, H. Naiki, Y. Goto, 2010, Protein science : a publication of the Protein Society.

Interaction between Aβ (1-42) and Aβ (1-40) in Alzheimer's β-amyloid fibril formation in vitro

F. Gejyo, K. Hasegawa, H. Naiki, 1999 .

Y. Fujibayashi, J. Kimura, M. Ueno, 1990 .

Iron (III) induces aggregation of hyperphosphorylated tau and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease.

Hironobu Naiki, R. Shin, K. Hasegawa, 2002, Journal of neurochemistry.

Treatment with Geranylgeranylacetone Induces Heat Shock Protein 70 and Attenuates Neonatal Hyperoxic Lung Injury in a Model of Bronchopulmonary Dysplasia

H. Naiki, A. Igarashi, Y. Ohshima, 2017, Lung.

3D structure of amyloid protofilaments of β2-microglobulin fragment probed by solid-state NMR

K. Iwata, Satoshi Takahashi, T. Fujiwara, 2006, Proceedings of the National Academy of Sciences.

Metal Ion-dependent Effects of Clioquinol on the Fibril Growth of an Amyloid β Peptide*

T. Kawai, T. Ban, H. Naiki, 2005, Journal of Biological Chemistry.

Molecular pathogenesis of human amyloidosis: Lessons from β2‐microglobulin‐related amyloidosis

K. Hasegawa, H. Naiki, I. Yamaguchi, 2016, Pathology international.

Laser-induced Propagation and Destruction of Amyloid β Fibrils*

T. Kawakami, O. Nishimura, H. Kuyama, 2010, The Journal of Biological Chemistry.

Real-time and Single Fibril Observation of the Formation of Amyloid β Spherulitic Structures*

S. Yuba, T. Kawasaki, T. Ban, 2006, Journal of Biological Chemistry.

Cerebrospinal fluid of Alzheimer's disease and dementia with Lewy bodies patients enhances α-synuclein fibril formation in vitro

M. Yoshita, K. Ono, M. Noguchi-Shinohara, 2007, Experimental Neurology.

Blood-borne factors inhibit Alzheimer's β-amyloid fibril formation in vitro

K. Ono, M. Noguchi-Shinohara, M. Samuraki, 2006, Experimental Neurology.

Antiamyloidogenic and proamyloidogenic chaperone effects of C-reactive protein and serum amyloid P component

K. Hasegawa, H. Naiki, V. Bellotti, 2017, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Kinetic modeling and determination of reaction constants of Alzheimer's beta-amyloid fibril extension and dissociation using surface plasmon resonance.

Kenjiro Ono, Masahito Yamada, Hironobu Naiki, 2002, Biochemistry.

The amyloid fibrils of the constant domain of immunoglobulin light chain

J. Kardos, H. Naiki, Y. Goto, 2010, FEBS letters.

Motor neuron disease with dementia combined with degeneration of striatonigral and pallidoluysian systems

K. Isaki, Y. Fukutani, M. Shiozawa, 2002, Acta Neuropathologica.

Apolipoprotein E and clusterin inhibit the early phase of amyloid-β aggregation in an in vitro model of cerebral amyloid angiopathy

K. Kikuta, Mark R. Wilson, Y. Ando, 2019, Acta Neuropathologica Communications.

Heparin‐induced amyloid fibrillation of β2‐microglobulin explained by solubility and a supersaturation‐dependent conformational phase diagram

H. Naiki, Y. Goto, M. So, 2017, Protein science : a publication of the Protein Society.

Core structure of amyloid fibril proposed from IR-microscope linear dichroism.

Teizo Kitagawa, Yuji Goto, Hironobu Naiki, 2004, Journal of the American Chemical Society.

Thermal response with exothermic effects of beta2-microglobulin amyloid fibrils and fibrillation.

H. Naiki, Y. Goto, K. Sasahara, 2009, Journal of molecular biology.

Optimum Amyloid Fibril Formation of a Peptide Fragment Suggests the Amyloidogenic Preference of β2-Microglobulin under Physiological Conditions*

K. Hasegawa, H. Naiki, Y. Goto, 2004, Journal of Biological Chemistry.

Destruction of Amyloid Fibrils of a β2-Microglobulin Fragment by Laser Beam Irradiation*

A. Kameda, T. Kawakami, T. Ban, 2009, Journal of Biological Chemistry.

NMR‐based characterization of a refolding intermediate of β2‐microglobulin labeled using a wheat germ cell‐free system

A. Kameda, H. Naiki, Y. Goto, 2009, Protein science : a publication of the Protein Society.

Mouse Senile Amyloidosis: Possible Horizontal Transmission In The Mouse Room

Xiaoying Fu, K. Higuchi, H. Naiki, 2007 .

Kinetic intermediates of β(2)-microglobulin fibril elongation probed by pulse-labeling H/D exchange combined with NMR analysis.

T. Ikegami, T. Konuma, H. Naiki, 2011, Journal of molecular biology.

Flow-induced Alignment of Amyloid Protofilaments Revealed by Linear Dichroism*

H. Naiki, Y. Goto, H. Yagi, 2007, Journal of Biological Chemistry.

Pre-steady-state kinetic analysis of the elongation of amyloid fibrils of beta(2)-microglobulin with tryptophan mutagenesis.

T. Konuma, H. Naiki, Y. Goto, 2010, Journal of molecular biology.

Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2

H. Jane Dyson, Peter E. Wright, Munehito Arai, 2009, Proceedings of the National Academy of Sciences.

A heterozygous female with Fabry disease due to a novel α-galactosidase A mutation exhibits a unique synaptopodin distribution in vacuolated podocytes.

K. Ohno, H. Sakuraba, H. Naiki, 2015, Clinical Nephrology.

Esophageal Erosion as a Possible Bacterial Entry Site in an Acute Lymphoblastic Leukemia Patient with Sepsis

H. Iwasaki, H. Naiki, T. Ueda, 2003, International journal of hematology.

Newly recognized cerebral infarctions on postmortem imaging: a report of three cases with systemic infectious disease

Hirohiko Kimura, Kunihiro Inai, Takahiro Yamauchi, 2017, BMC Medical Imaging.

Concentration-dependent inhibitory effects of apolipoprotein E on Alzheimer's beta-amyloid fibril formation in vitro.

F. Gejyo, H. Naiki, K. Nakakuki, 1997, Biochemistry.

Inhibition of β2-Microglobulin Amyloid Fibril Formation by α2-Macroglobulin*

K. Hasegawa, H. Naiki, Y. Goto, 2011, The Journal of Biological Chemistry.

Elderly onset congenital hepatic fibrosis with portal hypertension diagnosed after recurrent cholangitis: a case report

K. Harada, M. Ohtani, H. Naiki, 2022, Clinical Journal of Gastroenterology.

Apolipoprotein E and alpha 1-antichymotrypsin in dialysis-related amyloidosis.

F. Gejyo, H. Naiki, H. Kimura, 1997, Kidney international. Supplement.

Exploration of sepsis assisting parameters in hospital autopsied-patients: a prospective study

H. Naiki, K. Inai, S. Noriki, 2023, Scientific reports.

Visualization and Classification of Amyloid β Supramolecular Assemblies

Yuji Goto, Hironobu Naiki, T. Ban, 2007 .

Kinetic intermediates of β(2)-microglobulin fibril elongation probed by pulse-labeling H/D exchange combined with NMR analysis.

T. Ikegami, T. Konuma, H. Naiki, 2011, Journal of molecular biology.

Structural model of the amyloid fibril formed by beta(2)-microglobulin #21-31 fragment based on vibrational spectroscopy.

Teizo Kitagawa, Yuji Goto, Hironobu Naiki, 2005, Journal of the American Chemical Society.

Multiple inflammatory cytokine‐productive ThyL‐6 cell line established from a patient with thymic carcinoma

Y. Imamura, H. Naiki, T. Ueda, 2008, Cancer science.

Destruction of Amyloid Fibrils of Keratoepithelin Peptides by Laser Irradiation Coupled with Amyloid-specific Thioflavin T*

T. Kawakami, H. Naiki, Y. Goto, 2011, The Journal of Biological Chemistry.

A retrospective analysis of clinical features and treatment outcome in 21 patients with immunoglobulin M-related light-chain amyloidosis in Japan: a study from the Amyloidosis Research Committee

S. Iida, C. Nakaseko, H. Naiki, 2023, International journal of hematology.

Case With Transthyretin Amyloid Cardiomyopathy Complicated With Rapidly Progressive Aortic Stenosis Possibly Caused by Amyloid Deposition in the Aortic Valve.

S. Matoba, H. Naiki, M. Ueda, 2021, Circulation. Cardiovascular imaging.