Zhe Wang

发表

Determination of the binding mode for anti-inflammatory natural product xanthohumol with myeloid differentiation protein 2

Gaozhi Chen, G. Liang, Weitao Fu, 2016, Drug design, development and therapy.

Piperlongumine as a direct TrxR1 inhibitor with suppressive activity against gastric cancer.

P. Zou, J. Ji, Gaozhi Chen, 2016, Cancer letters.

A peptide derivative serves as a fibroblast growth factor 2 antagonist in human gastric cancer

Xiaokun Li, Gaozhi Chen, G. Liang, 2015, Tumor Biology.

Synthesis and biological evaluation of novel indole-2-one and 7-aza-2-oxindole derivatives as anti-inflammatory agents

Fengli Xu, Gaozhi Chen, Lili Fu, 2014, Drug design, development and therapy.

synthesis and biological evaluation of novel indole-2one and 7-aza-2-oxindole derivatives as anti-inflammatory agents

Fengli Xu, Gaozhi Chen, Lili Fu, 2014 .

Theoretical studies on FGFR isoform selectivity of FGFR1/FGFR4 inhibitors by molecular dynamics simulations and free energy calculations.

G. Liang, Weitao Fu, Lingfeng Chen, 2017, Physical chemistry chemical physics : PCCP.

Discovery and evaluation of novel anti-inflammatory derivatives of natural bioactive curcumin

Lili Fu, G. Liang, Zhe Wang, 2014, Drug design, development and therapy.

Prediction of Drug–Drug Interaction Between Dabrafenib and Irinotecan via UGT1A1-Mediated Glucuronidation

Ming Yan, Jun Cao, Zhe Wang, 2022, European Journal of Drug Metabolism and Pharmacokinetics.

Comparison of the drug-drug interactions potential of ibrutinib and acalabrutinib via inhibition of UDP-glucuronosyltransferase.

Ming Yan, Jun Cao, Zhe Wang, 2021, Toxicology and applied pharmacology.

Inhibition of Human UDP-Glucuronosyltransferase Enzyme by Belinostat: Implications for Drug-Drug Interactions.

Jun Cao, Zhe Wang, Xiaoyu Wang, 2020, Toxicology letters.

Bicyclol Attenuates Obesity-Induced Cardiomyopathy via Inhibiting NF-κB and MAPK Signaling Pathways

N. Chattipakorn, Gaojun Wu, Zhe Wang, 2022, Cardiovascular Drugs and Therapy.

Costunolide alleviates atherosclerosis in high-fat diet-fed ApoE^−/− mice through covalently binding to IKKβ and inhibiting NF-κB-mediated inflammation

Zhe Wang, Yi Wang, Wei-Jian Huang, 2022, Acta Pharmacologica Sinica.

ROS generation mediates the anti-cancer effects of WZ35 via activating JNK and ER stress apoptotic pathways in gastric cancer

P. Zou, G. Liang, Zhe Wang, 2015, Oncotarget.

EF24 induces ROS-mediated apoptosis via targeting thioredoxin reductase 1 in gastric cancer cells

P. Zou, G. Liang, Zhe Wang, 2016, OncoTarget.

Combination of dabrafenib with irinotecan might trigger off a higher frequency of adverse events by pharmacokinetic interaction

Ming Yan, Jun Cao, Zhe Wang, 2021 .

MD‐2 as the target of a novel small molecule, L6H21, in the attenuation of LPS‐induced inflammatory response and sepsis

Gaozhi Chen, G. Liang, Zhe Wang, 2015, British journal of pharmacology.

Insights into the binding mode of curcumin to MD-2: studies from molecular docking, molecular dynamics simulations and experimental assessments.

Gaozhi Chen, G. Liang, Weitao Fu, 2015, Molecular bioSystems.

Inhibition of 11β-HSD1 by LG13 improves glucose metabolism in type 2 diabetic mice.

Leping Zhao, G. Liang, Zhe Wang, 2015, Journal of molecular endocrinology.

Tabersonine attenuates Angiotensin II-induced cardiac remodeling and dysfunction through targeting TAK1 and inhibiting TAK1-mediated cardiac inflammation.

N. Chattipakorn, Ruijie Chen, Zhe Wang, 2022, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Discovery of a New Inhibitor of Myeloid Differentiation 2 from Cinnamamide Derivatives with Anti-Inflammatory Activity in Sepsis and Acute Lung Injury.

Xiaokun Li, Gaozhi Chen, Lili Fu, 2016, Journal of medicinal chemistry.

Synthesis and biological evaluation of allylated and prenylated mono-carbonyl analogs of curcumin as anti-inflammatory agents.

P. Zou, Gaozhi Chen, G. Liang, 2014, European journal of medicinal chemistry.

Design, synthesis and biological activity of novel asymmetric C66 analogs as anti-inflammatory agents for the treatment of acute lung injury.

G. Liang, Zhe Wang, Jianmin Zhou, 2015, European journal of medicinal chemistry.

Design, Synthesis, and Biological Evaluation of Novel Quinazoline Derivatives as Anti‐inflammatory Agents against Lipopolysaccharide‐induced Acute Lung Injury in Rats

G. Liang, Lingfeng Chen, Zhe Wang, 2015, Chemical biology & drug design.

Inhibition of Human UDP-Glucuronosyltransferase Enzyme by Dabrafenib: Implications for Drug-Drug Interactions.

Ming Yan, Jun Cao, Zhe Wang, 2021, Biomedical chromatography : BMC.

Synthesis and biological evaluation of novel oxindole-based RTK inhibitors as anti-cancer agents.

Xiaokun Li, Gaozhi Chen, G. Liang, 2014, Bioorganic & medicinal chemistry.

Inhibition of Rac1 activity alleviates PM2.5-induced pulmonary inflammation via the AKT signaling pathway.

Shui-juan Zhang, Weixi Zhang, Xiaolei Zeng, 2019, Toxicology letters.

Curcumin Analog L48H37 Prevents Lipopolysaccharide-Induced TLR4 Signaling Pathway Activation and Sepsis via Targeting MD2

Gaozhi Chen, G. Liang, Zhe Wang, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Curcumin analog L 48 H 37 prevents LPS-induced TLR 4 signaling pathway activation and sepsis via targeting MD 2

Gaozhi Chen, G. Liang, Zhe Wang, 2015 .

Curcumin Analog L 48 H 37 Prevents Lipopolysaccharide-Induced TLR 4 Signaling Pathway Activation and Sepsis via Targeting MD 2

Gaozhi Chen, G. Liang, Zhe Wang, 2015 .

Selective killing of gastric cancer cells by a small molecule targeting ROS‐mediated ER stress activation

P. Zou, G. Liang, Zhe Wang, 2016, Molecular carcinogenesis.

The Discovery of Potent and Stable Short Peptide FGFR1 Antagonist for Cancer Therapy.

Zhe Wang, Yuepiao Cai, Lei Fan, 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Selective killing of gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress activation

P. Zou, J. Ji, G. Liang, 2016, OncoTarget.

Discovery and evaluation of asymmetrical monocarbonyl analogs of curcumin as anti-inflammatory agents

Chengguang Zhao, G. Liang, Zhe Wang, 2014, Drug design, development and therapy.

Myeloid differential protein-2 inhibition improves diabetic cardiomyopathy via p38MAPK inhibition and AMPK pathway activation.

G. Liang, Zhe Wang, Yi Wang, 2022, Biochimica et biophysica acta. Molecular basis of disease.

Bicyclol ameliorates nonalcoholic fatty liver disease in mice via inhibiting MAPKs and NF-κB signaling pathways.

Zhongxiang Xiao, G. Liang, Zhe Wang, 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Synthesis and biological evaluation of novel semi-conservative mono-carbonyl analogs of curcumin as anti-inflammatory agents

P. Zou, Zhe Wang, Yuepiao Cai, 2015 .

Effect of the Polymorphism of Folylpolyglutamate Synthetase on Treatment of High-Dose Methotrexate in Pediatric Patients with Acute Lymphocytic Leukemia

Zhe Wang, Zhen Huang, Hongfei Tong, 2016, Medical science monitor : international medical journal of experimental and clinical research.

An Indole-2-Carboxamide Derivative, LG4, Alleviates Diabetic Kidney Disease Through Inhibiting MAPK-Mediated Inflammatory Responses

N. Chattipakorn, G. Liang, Zhe Wang, 2021, Journal of inflammation research.

Piperlongumine as a direct TrxR1 inhibitor with suppressive activity against gastric cancer.

P. Zou, J. Ji, Gaozhi Chen, 2016, Cancer letters.

Synthesis and biological evaluation of novel semi-conservative monocarbonyl analogs of curcumin as anti-inflammatory agents

P. Zou, G. Liang, Zhe Wang, 2015 .