A. Cléry

发表

Synergy between NMR measurements and MD simulations of protein/RNA complexes: application to the RRMs, the most common RNA recognition motifs

J. Šponer, M. Krepl, F. Allain, 2016, Nucleic acids research.

Structural Flexibility Enables Alternative Maturation, ARGONAUTE Sorting and Activities of miR168, a Global Gene Silencing Regulator in Plants.

O. Voinnet, C. Brosnan, Taichiro Iki, 2018, Molecular plant.

Structure of SRSF1 RRM1 bound to RNA reveals an unexpected bimodal mode of interaction and explains its involvement in SMN1 exon7 splicing

M. Okoniewski, M. Zavolan, J. Šponer, 2021, Nature communications.

SRSF1-Regulated Alternative Splicing in Breast Cancer.

Shuying Sun, Martin Akerman, Adrian R Krainer, 2015, Molecular cell.

A syn–anti conformational difference allows SRSF2 to recognize guanines and cytosines equally well

F. Allain, A. Cléry, J. Stévenin, 2012, The EMBO journal.

RNA recognition motifs: boring? Not quite.

Markus Blatter, F. Allain, A. Cléry, 2008, Current opinion in structural biology.

RRM-RNA recognition: NMR or crystallography…and new findings.

F. Allain, A. Cléry, G. M. Daubner, 2013, Current opinion in structural biology.

Structural study of the Fox-1 RRM protein hydration reveals a role for key water molecules in RRM-RNA recognition

J. Šponer, F. Damberger, M. Krepl, 2017, Nucleic acids research.

A second base pair interaction between U3 small nucleolar RNA and the 5′-ETS region is required for early cleavage of the yeast pre-ribosomal RNA

C. Branlant, A. Cléry, N. Marmier-Gourrier, 2011, Nucleic acids research.

TDP-43 oligomerization and RNA binding are codependent but their loss elicits distinct pathologies

C. Foglieni, M. Polymenidou, F. Allain, 2022, bioRxiv.

40S hnRNP particles are a novel class of nuclear biomolecular condensates

O. Mühlemann, M. Heller, Michal Domanski, 2022, Nucleic acids research.

The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity.

O. Mühlemann, M. Ruepp, M. Polymenidou, 2019, Molecular cell.

The structure of yeast Npl3 bound to RNA reveals a cooperative sequence-specific recognition and an RNA chaperone role in splicing

V. G. Panse, M. Robinson, S. Campagne, 2022, bioRxiv.

Single-stranded nucleic acid recognition: is there a code after all?

J. Boudet, F. Allain, A. Cléry, 2013, Structure.

Comparative analyses of the thermodynamic RNA binding signatures of different types of RNA recognition motifs

I. Jelesarov, F. Allain, A. Cléry, 2017, Nucleic acids research.

Structural basis for Cas9 off-target activity

M. Jinek, P. Arantes, Aakash Saha, 2021, Cell.

Isolated pseudo–RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition

A. Krainer, J. Valcárcel, Rahul Sinha, 2013, Proceedings of the National Academy of Sciences.

Exon‐independent recruitment of SRSF1 is mediated by U1 snRNP stem‐loop 3

F. Allain, I. Eperon, S. Campagne, 2021, The EMBO journal.

A Structural Biology Perspective of Proteins Involved in Splicing Regulation

F. Allain, A. Cléry, 2012 .

Characterization of the RNA recognition mode of hnRNP G extends its role in SMN2 splicing regulation

Ahmed S. Moursy, F. Allain, A. Cléry, 2014, Nucleic acids research.

One, Two, Three, Four! How Multiple RRMs Read the Genome Sequence.

F. Allain, A. Cléry, T. Afroz, 2015, Methods in enzymology.

An in vitro reconstituted U1 snRNP allows the study of the disordered regions of the particle and the interactions with proteins and ligands

D. Boehringer, J. Kohlbrecher, S. Campagne, 2021, Nucleic acids research.

RNA‐PROTACs: Degraders of RNA‐Binding Proteins

Jonathan Hall, F. Allain, A. Cléry, 2020, Angewandte Chemie.

Structural basis of a small molecule targeting RNA for a specific splicing correction

Anna Knörlein, Hasane Ratni, Jonathan Hall, 2019, Nature Chemical Biology.

Control of the polyamine biosynthesis pathway by G2-quadruplexes

Jonathan Hall, H. Lightfoot, F. Allain, 2018, eLife.

Plastidial NAD-Dependent Malate Dehydrogenase: A Moonlighting Protein Involved in Early Chloroplast Development through Its Interaction with an FtsH12-FtsHi Protease Complex[OPEN]

S. Zeeman, Benjamin A. Maier, O. Kötting, 2018, Plant Cell.

Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7

F. Allain, A. Cléry, A. Moursy, 2017, eLife.

Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers

Adrian R. Krainer, Balazs Banfai, Tobias Heckel, 2017, Nature Communications.

Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2-β1

Stefan Stamm, S. Stamm, C. Dominguez, 2011, Nature Structural &Molecular Biology.

Analysis of Sequence and Structural Features That Identify the B/C Motif of U3 Small Nucleolar RNA as the Recognition Site for the Snu13p-Rrp9p Protein Pair

C. Branlant, A. Cléry, F. Leclerc, 2006, Molecular and Cellular Biology.

A structural, phylogenetic, and functional study of 15.5-kD/Snu13 protein binding on U3 small nucleolar RNA.

A. Cléry, B. Charpentier, N. Marmier-Gourrier, 2003, RNA.

switchSENSE: A new technology to study protein-RNA interactions.

F. Allain, A. Cléry, T. Welte, 2017, Methods.

FROM STRUCTURE TO FUNCTION OF RNA BINDING DOMAINS

F. Allain, A. Cléry, 2013 .

Specific inhibition of splicing factor activity by decoy RNA oligonucleotides

E. Levanon, Saran Kumar, T. Geiger, 2019, Nature Communications.

The archaeal sRNA binding protein L7Ae has a 3D structure very similar to that of its eukaryal counterpart while having a broader RNA-binding specificity.

A. Aubry, C. Branlant, A. Cléry, 2004, Journal of molecular biology.

An improved definition of the RNA-binding specificity of SECIS-binding protein 2, an essential component of the selenocysteine incorporation machinery

A. Krol, V. Bourguignon-Igel, C. Branlant, 2007, Nucleic acids research.

Specific inhibition of splicing factor activity by decoy RNA oligonucleotides

E. Levanon, Saran Kumar, T. Geiger, 2019, Nature Communications.

Loss of TDP‐43 oligomerization or RNA binding elicits distinct aggregation patterns

C. Foglieni, M. Polymenidou, F. Allain, 2023, The EMBO journal.

RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription

M. Diaz, Yaroslav V Nikolaev, R. Giambruno, 2023, Science advances.

Inosine Substitutions in RNA Activate Latent G-Quadruplexes.

S. Bergmann, Jonathan Hall, R. Zenobi, 2021, Journal of the American Chemical Society.

RNA recognition motifs: boring? Not quite.

F. Allain, A. Cléry, M. Blatter, 2008, Current opinion in structural biology.

RNA recognition by Npl3p reveals U2 snRNA-binding compatible with a chaperone role during splicing

V. G. Panse, Mark D. Robinson, S. Campagne, 2023, Nature communications.

Isolated pseudo–RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition

A. Krainer, J. Valcárcel, Rahul Sinha, 2013, Proceedings of the National Academy of Sciences.