Ian Mitchelle S. de Vera

发表

Deconvolution of Complex 1D NMR Spectra Using Objective Model Selection

Travis S. Hughes, Henry D. Wilson, Ian Mitchelle S. de Vera, 2015, PloS one.

Effects of PRE and POST therapy drug‐pressure selected mutations on HIV‐1 protease conformational sampling

Ian Mitchelle S. de Vera, B. Dunn, J. Carter, 2014, FEBS letters.

Didehydro-Cortistatin A Inhibits HIV-1 by Specifically Binding to the Unstructured Basic Region of Tat

Ian Mitchelle S. de Vera, J. Nowak, D. Kojetin, 2019, mBio.

An alternate binding site for PPARγ ligands

Travis S. Hughes, Ian Mitchelle S. de Vera, Douglas J. Kojetin, 2014, Nature Communications.

Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication

Ian Mitchelle S. de Vera, T. Spicer, D. Kojetin, 2016, Antimicrobial Agents and Chemotherapy.

Assessment of NR4A Ligands That Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1.

Ian Mitchelle S. de Vera, D. Kojetin, T. Kamenecka, 2020, Journal of medicinal chemistry.

Mechanistic insight into protein modification and sulfur mobilization activities of noncanonical E1 and associated ubiquitin‐like proteins of Archaea

Ian Mitchelle S. de Vera, D. Kojetin, S. Uthandi, 2016, The FEBS journal.

The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids.

Ian Mitchelle S. de Vera, T. Burris, Thomas Koelblen, 2020, Cell chemical biology.

Structural Insights into Estrogen Receptors and Antiestrogen Therapies

Ian Mitchelle S. de Vera, T. Burris, Udayanga S. Wanninayake, 2018, Estrogen Receptor and Breast Cancer.

Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation

Ian Mitchelle S. de Vera, B. Leavitt, J. Morley, 2022, bioRxiv.

Identification of potent small molecule inhibitors of SARS-CoV-2 entry

Ian Mitchelle S. de Vera, T. Spicer, M. Farzan, 2021, bioRxiv.

Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes

Ian Mitchelle S. de Vera, J. Nwachukwu, D. Kojetin, 2017, Nucleic acids research.

Conserved sequence-specific lincRNA–steroid receptor interactions drive transcriptional repression and direct cell fate

Ian Mitchelle S. de Vera, D. Kojetin, E. Ortlund, 2014, Nature Communications.

The Tat inhibitor didehydro‐cortistatin A suppresses SIV replication and reactivation

Ian Mitchelle S. de Vera, D. Kojetin, Suzie Thenin-Houssier, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Synergistic Regulation of Coregulator/Nuclear Receptor Interaction by Ligand and DNA.

Ian Mitchelle S. de Vera, Patrick R Griffin, David P Marciano, 2017, Structure.

Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space

Ian Mitchelle S. de Vera, D. Kojetin, E. Ortlund, 2015, Proceedings of the National Academy of Sciences.

Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements

Ian Mitchelle S. de Vera, J. Nwachukwu, D. Kojetin, 2018, Nature Communications.

Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1.

Henry D. Wilson, Ian Mitchelle S. de Vera, T. Creamer, 2016, ACS chemical biology.

Probing the Complex Binding Modes of the PPARγ Partial Agonist 2-Chloro-N-(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl)benzenesulfonamide (T2384) to Orthosteric and Allosteric Sites with NMR Spectroscopy.

Ian Mitchelle S. de Vera, T. Hughes, D. Kojetin, 2016, Journal of medicinal chemistry.

Antisense oligonucleotide strategies to increase progranulin levels for frontotemporal dementia

Ian Mitchelle S. de Vera, B. Leavitt, J. Morley, 2022 .

Defining a canonical ligand-binding pocket in the orphan nuclear receptor Nurr1

Ian Mitchelle S. de Vera, T. Hughes, P. Griffin, 2018, bioRxiv.

Defining a conformational ensemble that directs activation of PPARγ

Ian Mitchelle S. de Vera, T. Cheatham, T. Hughes, 2018, Nature Communications.

Defining a conformational ensemble that directs activation of PPARγ

Ian Mitchelle S. de Vera, T. Cheatham, T. Hughes, 2018, Nature Communications.

Assessment of NR4A Ligands that Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1

Ian Mitchelle S. de Vera, D. Kojetin, T. Kamenecka, 2020, bioRxiv.

Pulsed EPR characterization of HIV-1 protease conformational sampling and inhibitor-induced population shifts.

Ian Mitchelle S. de Vera, Thomas M. Casey, J. Carter, 2016, Physical chemistry chemical physics : PCCP.

Inhibitor-induced conformational shifts and ligand-exchange dynamics for HIV-1 protease measured by pulsed EPR and NMR spectroscopy.

Ian Mitchelle S. de Vera, B. Dunn, C. Simmerling, 2012, The journal of physical chemistry. B.

Correlating conformational shift induction with altered inhibitor potency in a multidrug resistant HIV-1 protease variant.

Ian Mitchelle S. de Vera, G. Fanucci, Mandy E. Blackburn, 2012, Biochemistry.

Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915.

Ian Mitchelle S. de Vera, T. Burris, T. Boehm, 2023, European journal of medicinal chemistry.

Advances in Orphan Nuclear Receptor Pharmacology: A New Era in Drug Discovery.

Ian Mitchelle S. de Vera, 2018, ACS pharmacology & translational science.

Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation

Ian Mitchelle S. de Vera, B. Leavitt, J. Morley, 2022, bioRxiv.

Analysis of monoglycerides, diglycerides, sterols, and free fatty acids in coconut (Cocos nucifera L.) oil by 31P NMR spectroscopy.

Ian Mitchelle S. de Vera, F. Dayrit, Olivia E. M. Buenafe, 2008, Journal of agricultural and food chemistry.

Effects of PRE and POST therapy drug‐pressure selected mutations on HIV‐1 protease conformational sampling

Ian Mitchelle S. de Vera, B. Dunn, J. Carter, 2014, FEBS letters.