P. Ajitkumar

发表

A method for the enrichment, isolation, and validation of mycobacterium smegmatis population surviving in the presence of bactericidal concentrations of rifampicin and moxifloxacin.

Atul Pradhan, S. Swaminath, Kishor Jakkala, 2021, FEMS microbiology letters.

Redox-dependent condensation of the mycobacterial nucleoid by WhiB4

Munia Ganguli, Amit Singh, M. Vij, 2017, bioRxiv.

Redox-Dependent Condensation Of the Mycobacterial Nucleoid By WhiB4

Munia Ganguli, Amit Singh, A. Seshasayee, 2017, bioRxiv.

In vitro polymerization of Mycobacterium leprae FtsZ OR Mycobacterium tuberculosis FtsZ is revived or abolished, respectively, by reciprocal mutation of a single residue.

R. Srinivasan, Prabuddha L. Gupta, P. Ajitkumar, 2008, Biochemical and biophysical research communications.

GTP/GDP binding stabilizes bacterial cell division protein FtsZ against degradation by FtsH protease in vitro.

R. Srinivasan, P. Ajitkumar, S. Indi, 2007, Biochemical and biophysical research communications.

Unique Biochemical Features of the Cytokinetic Protein FtsZ of Mycobacteria

Prabuddha L. Gupta, Atul Pradhan, P. Ajitkumar, 2017, Mycobacterium - Research and Development.

Mycobacterium smegmatis strains genetically resistant to moxifloxacin emerge de novo from the moxifloxacin-surviving population containing high levels of superoxide, H2O2, hydroxyl radical, and Fe (II)

R. Nair, Kishor Jakkala, P. Ajitkumar, 2022, International journal of mycobacteriology.

Bacterial cell division protein FtsZ is a specific substrate for the AAA family protease FtsH.

R. Srinivasan, P. Ajitkumar, G. Anilkumar, 2001, Microbiology.

Mycobacterial Cultures Contain Cell Size and Density Specific Sub-populations of Cells with Significant Differential Susceptibility to Antibiotics, Oxidative and Nitrite Stress

R. Nair, Atul Pradhan, S. Swaminath, 2017, Front. Microbiol..

Asymmetric cell division in Mycobacterium tuberculosis and its unique features

P. Ajitkumar, Srinivasan Vijay, Jees Sebastian, 2014, Archives of Microbiology.

Mycobacterium tuberculosis Cells Surviving in the Continued Presence of Bactericidal Concentrations of Rifampicin in vitro Develop Negatively Charged Thickened Capsular Outer Layer That Restricts Permeability to the Antibiotic

R. Nair, S. Swaminath, P. Ajitkumar, 2020, Frontiers in Microbiology.

Reduced Permeability to Rifampicin by Capsular Thickening as a Mechanism of Antibiotic Persistence in Mycobacterium tuberculosis

S. Swaminath, P. Ajitkumar, Jees Sebastian, 2019, bioRxiv.

Determination of growth inhibitory action point of interferon gamma on WISH cells in cell cycle progression and the window of responsiveness of the cells to the interferon.

S. Patil, P. Ajitkumar, Surabhi Vashistha, 2007, Cytokine.

Growth and division mechanisms by which genetic resisters emerge from the rifampicin-surviving population of differentially antibiotic-susceptible mycobacterial subpopulations

R. Nair, Atul Pradhan, S. Swaminath, 2022, International journal of mycobacteriology.

The H2O2 inherently released by the mycobacterial minor subpopulation enhances the survival of the major kin subpopulation against rifampicin

V. Srinivasan, R. Nair, Kishor Jakkala, 2022, Current research in microbial sciences.

Deletion of rifampicin-inactivating mono-ADP-ribosyl transferase gene of Mycobacterium smegmatis globally altered gene expression profile that favoured increase in ROS levels and thereby antibiotic resister generation

R. Nair, Atul Pradhan, S. Swaminath, 2022, Current research in microbial sciences.

The ftsZ Gene of Mycobacterium smegmatis is expressed Through Multiple Transcripts

Sougata Roy, Prabuddha L. Gupta, P. Ajitkumar, 2011, The open microbiology journal.

Mycobacterium tuberculosis Expresses ftsE Gene Through Multiple Transcripts

Sougata Roy, M. Arumugam, P. Ajitkumar, 2011, Current Microbiology.

Complete identity and expression of StfZ, the cis-antisense RNA to the mRNA of the cell division gene ftsZ, in Escherichia coli

R. Nair, Atul Pradhan, Kishor Jakkala, 2022, Frontiers in Microbiology.

Cloning and expression of the gene coding for FtsH protease from Mycobacterium tuberculosis H37Rv.

P. Ajitkumar, G. Anilkumar, M. Chauhan, 1998, Gene.

The Multifunctional PE_PGRS11 Protein from Mycobacterium tuberculosis Plays a Role in Regulating Resistance to Oxidative Stress*

N. Chandra, Rashmi Chaturvedi, S. Patil, 2010, The Journal of Biological Chemistry.

Heterogeneity of ROS levels in antibiotic-exposed mycobacterial subpopulations confers differential susceptibility.

R. Nair, S. Swaminath, P. Ajitkumar, 2019, Microbiology.

Curcumin reduces the antimicrobial activity of ciprofloxacin against Salmonella typhimurium and Salmonella typhi.

V. Nagaraja, S. Marathe, D. Chakravortty, 2013, The Journal of antimicrobial chemotherapy.

Exposure to Interferon γ Decreases Levels and Activity of Key Cell Cycle Proteins Resulting in Severe Growth Arrest of the Human Non-Transformed Cell Line, WISH

P. Ajitkumar, Surabhi Vashistha, 2010 .

Histidine 117 in the His-Gly-Ser-Asp motif is Required for the Biochemical Activities of Nucleoside Diphosphate Kinase of Mycobacterium smegmatis

M. Arumugam, P. Ajitkumar, 2012, The open biochemistry journal.

Cloning, expression, purification, and biochemical characterisation of the FIC motif containing protein of Mycobacterium tuberculosis.

N. Chandra, Raghu Bhagavat, P. Ajitkumar, 2012, Protein expression and purification.

Analysis of degradation of bacterial cell division protein FtsZ by the ATP-dependent zinc-metalloprotease FtsH in vitro.

R. Srinivasan, P. Ajitkumar, H. Rajeswari, 2008, Microbiological research.

Functional characterization of AAA family FtsH protease of Mycobacterium tuberculosis.

R. Srinivasan, P. Ajitkumar, G. Anilkumar, 2006, FEMS microbiology letters.

Genomic organization and in vivo characterization of proteolytic activity of FtsH of Mycobacterium smegmatis SN2.

R. Srinivasan, P. Ajitkumar, G. Anilkumar, 2004, Microbiology.

Genomic organization and in vivo characterization of proteolytic activity of FtsH of Mycobacterium smegmatis SN 2

R. Srinivasan, P. Ajitkumar, G. Anilkumar, 2004 .

Expression profiling of sodium butyrate (NaB)-treated cells: identification of regulation of genes related to cytokine signaling and cancer metastasis by NaB

K. Somasundaram, P. Ajitkumar, J. Joseph, 2004, Oncogene.

Hypoxic Non-replicating Persistent Mycobacterium tuberculosis Develops Thickened Outer Layer That Helps in Restricting Rifampicin Entry

Kishor Jakkala, P. Ajitkumar, 2019, Front. Microbiol..

NDK Interacts with FtsZ and Converts GDP to GTP to Trigger FtsZ Polymerisation - A Novel Role for NDK

R. Srinivasan, Prabuddha L. Gupta, M. Arumugam, 2015, PloS one.

Mycobacterium tuberculosis FtsZ requires at least one arginine residue at the C-terminal end for polymerization in vitro.

N. Chandra, Raghu Bhagavat, Praveen Anand, 2010, Acta biochimica et biophysica Sinica.

Molecular characterisation of ABC transporter type FtsE and FtsX proteins of Mycobacterium tuberculosis

P. Ajitkumar, Usha Veeraraghavan, H. Rajeswari, 2006, Archives of Microbiology.

Evidence that multiple residues on both the α-helices of the class I MHC molecule are simultaneously recognized by the T cell receptor

D. Wiley, J. Bluestone, S. Nathenson, 1988, Cell.

Elevated Levels of Three Reactive Oxygen Species and Fe(II) in the Antibiotic-Surviving Population of Mycobacteria Facilitate De Novo Emergence of Genetic Resisters to Antibiotics

R. Nair, Atul Pradhan, Kishor Jakkala, 2022, Antimicrobial agents and chemotherapy.

Bacterial cell division protein FtsZ is stable against degradation by AAA family protease FtsH in Escherichia coli cells

R. Srinivasan, P. Ajitkumar, 2007, Journal of basic microbiology.

Mycobacterial Populations Partly Change the Proportions of the Cells Undergoing Asymmetric/Symmetric Divisions in Response to Glycerol Levels in Growth Medium

Atul Pradhan, Kishor Jakkala, P. Ajitkumar, 2021, Cells.

Unveiling the physiological mechanisms that drive the emergence of antibiotic resisters from antibiotic persister population of mycobacteria

R. Nair, Atul Pradhan, Kishor Jakkala, 2019, bioRxiv.

Heat and SDS insensitive NDK dimers are largely stabilised by hydrophobic interaction to form functional hexamer in Mycobacterium smegmatis.

M. Arumugam, P. Ajitkumar, 2013, Acta biochimica Polonica.

Mycobacterium tuberculosis and Escherichia coli nucleoside diphosphate kinases lack multifunctional activities to process uracil containing DNA.

Pradeep Kumar, R. Srinivasan, P. Ajitkumar, 2004, DNA repair.

A Minor Subpopulation of Mycobacteria Inherently Produces High Levels of Reactive Oxygen Species That Generate Antibiotic Resisters at High Frequency From Itself and Enhance Resister Generation From Its Major Kin Subpopulation

R. Nair, P. Ajitkumar, Deepti Sharan, 2019, Front. Microbiol..

The rifampicin-inactivating mono-ADP-ribosyl transferase of Mycobacterium smegmatis significantly influences reactive oxygen species levels in the actively growing cells

R. Nair, Atul Pradhan, S. Swaminath, 2020, bioRxiv.

De Novo Emergence of Genetically Resistant Mutants of Mycobacterium tuberculosis from the Persistence Phase Cells Formed against Antituberculosis Drugs In Vitro

R. Nair, Atul Pradhan, S. Swaminath, 2016, Antimicrobial Agents and Chemotherapy.

A C-terminal deletion mutant of Mycobacterium tuberculosis FtsZ shows fast polymerization in vitro.

R. Srinivasan, Prabuddha L. Gupta, P. Ajitkumar, 2004, Microbiology.

Growth inhibition of human promonocytic leukaemic U937 cells by interferon gamma is irreversible and not cell cycle phase-specific.

P. Ajitkumar, P. Supriya, C. Joshi, 1999, Cytokine.

Mycobacterium smegmatis moxifloxacin persister cells produce high levels of hydroxyl radical, generating genetic resisters selectable not only with moxifloxacin, but also with ethambutol and isoniazid.

R. Nair, Atul Pradhan, S. Swaminath, 2019, Microbiology.

Unveiling Unusual Features of Formation of Septal Partition and Constriction in Mycobacteria—an Ultrastructural Study

P. Ajitkumar, Deepak Anand, Srinivasan Vijay, 2011, Journal of bacteriology.

MtFtsX a predicted membrane domain of ABC transporter complex MtFtsEX of Mycobacterium tuberculosis interacts with the cell division protein MtFtsZ

R. Srinivasan, P. Ajitkumar, M. Mir, 2019, International journal of mycobacteriology.

Identification and semi-quantitative analysis of Mycobacterium tuberculosis H37Rv ftsZ gene-specific promoter activity-containing regions.

M. Niederweis, Sougata Roy, P. Ajitkumar, 2004, Research in microbiology.

Highly fluorescent GFPm2+‐based genome integration‐proficient promoter probe vector to study Mycobacterium tuberculosis promoters in infected macrophages

Sougata Roy, P. Ajitkumar, Y. Narayana, 2011, Microbial biotechnology.

Transcriptional Analysis of the Principal Cell Division Gene, ftsZ, of Mycobacterium tuberculosis

Sougata Roy, P. Ajitkumar, 2005, Journal of bacteriology.

Mycobacterium tuberculosis Cell Division Protein, FtsE, is an ATPase in Dimeric Form

S. Ramakumar, M. Arumugam, S. Mondal, 2015, The Protein Journal.

Complete identity of the cis-asRNA StfZ and its influence on FtsZ protein level and cell division in Escherichia coli

R. Nair, Atul Pradhan, Kishor Jakkala, 2022, bioRxiv.

Unique Mode of Cell Division by the Mycobacterial Genetic Resister Clones Emerging De Novo from the Antibiotic-Surviving Population

R. Nair, Atul Pradhan, S. Swaminath, 2020, mSphere.

The C-terminally truncated MtFtsZ-DeltaC169 mutant of Mycobacterium tuberculosis FtsZ shows GTPase and GTP-induced, GTP-specific polymerization activities in vitro.

R. Srinivasan, Prabuddha L. Gupta, P. Ajitkumar, 2004, Microbiology.

IFN-gamma inhibits growth of WISH cells in a cell cycle phase-specific manner.

P. Ajitkumar, P. Supriya, C. Joshi, 1998, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Molecular Mapping of Antigenic and Cytotoxic T Lymphocyte Recognition Determinants on the Major Histocompatibility Complex Class I Molecule Kb Using In Vitro Mutant Cell Lines

J. Bluestone, S. Nathenson, P. Ajitkumar, 1989 .