Sean B. Christensen

发表

Development of Conformationally Constrained α-RgIA Analogues as Stable Peptide Antagonists of Human α9α10 Nicotinic Acetylcholine Receptors.

J. McIntosh, Nan Zheng, Sean B. Christensen, 2020, Journal of medicinal chemistry.

Positional Scanning Mutagenesis of α-Conotoxin PeIA Identifies Critical Residues That Confer Potency and Selectivity for α6/α3β2β3 and α3β2 Nicotinic Acetylcholine Receptors*

J. McIntosh, Sean B. Christensen, A. Hone, 2013, The Journal of Biological Chemistry.

α-Conotoxin OmIA Is a Potent Ligand for the Acetylcholine-binding Protein as Well as α3β2 and α7 Nicotinic Acetylcholine Receptors*

Igor Tsigelny, Todd T. Talley, Palmer Taylor, 2006, Journal of Biological Chemistry.

Expression of α3β2β4 nicotinic acetylcholine receptors by rat adrenal chromaffin cells determined using novel conopeptide antagonists

J. McIntosh, T. Dyhring, Sean B. Christensen, 2020, Journal of neurochemistry.

Discovery, synthesis, and structure activity of a highly selective alpha7 nicotinic acetylcholine receptor antagonist.

D. Yoshikami, J. Rivier, J. McIntosh, 2007, Biochemistry.

A Novel Inhibitor of α9α10 Nicotinic Acetylcholine Receptors from Conus vexillum Delineates a New Conotoxin Superfamily

R. Norton, J. McIntosh, Sean B. Christensen, 2013, PloS one.

Evolution of Conus peptide toxins: analysis of Conus californicus Reeve, 1844.

N. Puillandre, J. Biggs, B. Olivera, 2010, Molecular phylogenetics and evolution.

RgIA4 Accelerates Recovery from Paclitaxel-Induced Neuropathic Pain in Rats

J. McIntosh, Sean B. Christensen, K. L. Tucker, 2019, Marine drugs.

Discovery of Methylene Thioacetal-Incorporated α-RgIA Analogues as Potent and Stable Antagonists of the Human α9α10 Nicotinic Acetylcholine Receptor for the Treatment of Neuropathic Pain.

J. McIntosh, Nan Zheng, Sean B. Christensen, 2021, Journal of medicinal chemistry.

α-Conotoxin PeIA[S9H,V10A,E14N] Potently and Selectively Blocks α6β2β3 versus α6β4 Nicotinic Acetylcholine Receptors

J. Lindstrom, J. McIntosh, Sean B. Christensen, 2012, Molecular Pharmacology.

α-Conotoxin VnIB from Conus ventricosus is a potent and selective antagonist of α6β4* nicotinic acetylcholine receptors

J. McIntosh, B. Olivera, Sean B. Christensen, 2019, Neuropharmacology.

αS-conotoxin GVIIIB potently and selectively blocks α9α10 nicotinic acetylcholine receptors.

J. McIntosh, B. Olivera, P. Bandyopadhyay, 2015, Biochemical pharmacology.

α‐Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between 06 β4 and 0:6 β2 nicotinic acetylcholine receptors and blocks nicotine‐stimulated norepinephrine release

J. Changeux, U. Maskos, M. Biasi, 2010 .

α-Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between α6ß4 and α6ß2 nicotinic acetylcholine receptors and blocks nicotine-stimulated norepinephrine release.

J. Changeux, U. Maskos, J. McIntosh, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The atypical α -conotoxin LtIA from C onus litteratus targets a novel microsite of the alpha3beta2 nicotinic receptor*

D. Craik, R. Lewis, N. Daly, 2010 .

Synthesis and characterization of [ 125 I] α -conotoxin ArIB[V11L;V16A], a selective α 7 nAChR antagonist.

A. C. Collins, A. Collins, M. Marks, 2008 .

Characterization of a Novel α-Conotoxin from Conus textile That Selectively Targets α6/α3β2β3 Nicotinic Acetylcholine Receptors*

D. Craik, J. McIntosh, Sean B. Christensen, 2012, The Journal of Biological Chemistry.

PeIA-5466: A novel peptide antagonist containing non-natural amino acids that selectively targets α3β2 nicotinic acetylcholine receptors.

J. McIntosh, Sean B. Christensen, P. Whiteaker, 2019, Journal of medicinal chemistry.

Novel α-CTx TxIB Selectively Blocks α 6 / α 3 β 2 β 3 nAChRs 1 Characterization of a Novel α-Conotoxin from Conus textile that Selectively Targets α 6 / α 3 β 2 β 3 Nicotinic Acetylcholine Receptors

D. Craik, J. McIntosh, Sean B. Christensen, 2012 .

A novel fluorescent α‐conotoxin for the study of α7 nicotinic acetylcholine receptors

J. McIntosh, Yingxian Xiao, Sean B. Christensen, 2009, Journal of neurochemistry.

Computational and Functional Mapping of Human and Rat α6β4 Nicotinic Acetylcholine Receptors Reveals Species-Specific Ligand-Binding Motifs.

D. Craik, Q. Kaas, J. McIntosh, 2021, Journal of medicinal chemistry.

RgIA4 Potently Blocks Mouse α9α10 nAChRs and Provides Long Lasting Protection against Oxaliplatin-Induced Cold Allodynia

E. Glowatzki, J. Pin, D. Servent, 2017, Front. Cell. Neurosci..

Inhibition of α9α10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain

C. Ghelardini, J. McIntosh, L. di Cesare Mannelli, 2017, Proceedings of the National Academy of Sciences.

Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist

D. Craik, P. Harvey, Q. Kaas, 2015, Proceedings of the National Academy of Sciences.

Characterization of a novel α-conotoxin TxID from Conus textile that potently blocks rat α3β4 nicotinic acetylcholine receptors.

D. Craik, P. Harvey, J. McIntosh, 2013, Journal of medicinal chemistry.

Synthesis and Characterization of 125I-α-Conotoxin ArIB[V11L;V16A], a Selective α7 Nicotinic Acetylcholine Receptor Antagonist

A. Collins, M. Marks, J. McIntosh, 2008, Journal of Pharmacology and Experimental Therapeutics.

Selective Penicillamine Substitution Enables Development of a Potent Analgesic Peptide that Acts through a Non-Opioid-Based Mechanism.

J. McIntosh, B. Olivera, Sean B. Christensen, 2021, Journal of medicinal chemistry.

RgIA4 Prevention of Acute Oxaliplatin-Induced Cold Allodynia Requires α9-Containing Nicotinic Acetylcholine Receptors and CD3+ T-Cells

J. McIntosh, Sean B. Christensen, Peter N. Huynh, 2022, Cells.

Molecular determinants of α-conotoxin potency for inhibition of human and rat α6β4 nicotinic acetylcholine receptors

D. Craik, P. Harvey, J. McIntosh, 2018, The Journal of Biological Chemistry.

Atypical α-Conotoxin LtIA from Conus litteratus Targets a Novel Microsite of the α3β2 Nicotinic Receptor*

D. Craik, R. Lewis, N. Daly, 2010, The Journal of Biological Chemistry.

3-D Printed Ultem 9085 Testing and Analysis

Daniel Aguilar, Sean Christensen, Emmet J. Fox, 2015 .

Structure and Biological Activity of a Turripeptide from Unedogemmula bisaya Venom.

N. Daly, B. Olivera, M. Flores, 2017, Biochemistry.

The Tunicate Metabolite 2-(3,5-Diiodo-4-methoxyphenyl)ethan-1-amine Targets Ion Channels of Vertebrate Sensory Neurons.

B. Olivera, E. Schmidt, C. Reilly, 2021, ACS chemical biology.

The tunicate metabolite 2-(3,5-diiodo-4-methoxyphenyl)ethan-1-amine targets ion channels of vertebrate sensory neurons

K. Chase, B. Olivera, E. Schmidt, 2021, bioRxiv.

Characterization of a novel α-conotoxin TxID from Conus textile that potently blocks rat α3β4 nicotinic acetylcholine receptors.

D. Craik, P. Harvey, Sean B. Christensen, 2013, Journal of medicinal chemistry.

Analogs of α‐conotoxin PnIC selectively inhibit α7β2‐ over α7‐only subtype nicotinic acetylcholine receptors via a novel allosteric mechanism

Sean B. Christensen, P. Whiteaker, M. Watkins, 2023, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

ArIB(V11L;V16A), a Selective 7 Nicotinic Acetylcholine Receptor Antagonist □ S

A. C. Collins, M. Marks, J. McIntosh, 2008 .