W. Qu

发表

Dorsal Striatum Dopamine Levels Fluctuate Across the Sleep–Wake Cycle and Respond to Salient Stimuli in Mice

Zhi-Li Huang, Hui Dong, Juan Wang, 2019, Front. Neurosci..

Entire Frequency Domain Analysis of Rodent EEG and EMG Recordings Using Relative Thresholds

Zhi-Li Huang, M. Yao, W. Qu, 2017 .

Keeping the right time in space: importance of circadian clock and sleep for physiology and performance of astronauts

Zhi-Li Huang, Xiaoping Chen, Shanguang Chen, 2014, Military Medical Research.

Lipocalin-type prostaglandin D synthase/β-trace is a major amyloid β-chaperone in human cerebrospinal fluid

Y. Urade, Zhi-Li Huang, I. Mohri, 2007, Proceedings of the National Academy of Sciences.

Activation of Parabrachial Nucleus Glutamatergic Neurons Accelerates Reanimation from Sevoflurane Anesthesia in Mice

Zhi-Li Huang, Bo Xiong, W. Qu, 2019, Anesthesiology.

Paeoniflorin exerts analgesic and hypnotic effects via adenosine A1 receptors in a mouse neuropathic pain model

Zhi-Li Huang, Jiang-Fan Chen, W. Qu, 2015, Psychopharmacology.

Paeoniflorin Promotes Non-rapid Eye Movement Sleep via Adenosine A1 Receptors

Y. Yanagawa, Zhi-Li Huang, Jiang-Fan Chen, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Piromelatine exerts antinociceptive effect via melatonin, opioid, and 5HT1A receptors and hypnotic effect via melatonin receptors in a mouse model of neuropathic pain

Y. Urade, Zhi-Li Huang, M. Laudon, 2014, Psychopharmacology.

REPEATED SLEEP RESTRICTION AND SPATIAL LEARNING/MEMORY

Zhi-Li Huang, W. Qu, Mingchen Yao, 2012 .

Paraventricular hypothalamic nucleus are essential for arousal promotion and maintenance

Zhi-Li Huang, W. Qu, Sha Jiang, 2021 .

Orexin A promotes histamine, but not norepinephrine or serotonin, release in frontal cortex of mice

Zhi-Li Huang, W. Qu, N. Eguchi, 2005, Acta Pharmacologica Sinica.

Whole-Brain Monosynaptic Afferents to Rostromedial Tegmental Nucleus Gamma-Aminobutyric Acid-Releasing Neurons in Mice

Zhi-Li Huang, W. Qu, Su-Rong Yang, 2022, Frontiers in Neuroscience.

Doxepin and diphenhydramine increased non-rapid eye movement sleep through blockade of histamine H1 receptors

Y. Urade, Zhi-Li Huang, W. Qu, 2015, Pharmacology Biochemistry and Behavior.

Whole-brain monosynaptic outputs and presynaptic inputs of GABAergic neurons in the vestibular nuclei complex of mice

Zhi-Li Huang, Jing Wang, W. Qu, 2022, Frontiers in Neuroscience.

A cluster of mesopontine GABAergic neurons suppresses REM sleep and curbs cataplexy

Zhi-Li Huang, Hui Dong, W. Qu, 2022, Cell Discovery.

Trihexyphenidyl increases delta activity in non-rapid eye movement sleep without impairing cognitive function in rodent models

Zhi-Li Huang, W. Qu, Su-Rong Yang, 2022, Neuropharmacology.

Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice

S. Schiffmann, Y. Urade, Zhi-Li Huang, 2017, Nature Communications.

Sevoflurane depresses neurons in the medial parabrachial nucleus by potentiating postsynaptic GABAA receptors and background potassium channels

Zhi-Li Huang, W. Qu, Tian-xiao Wang, 2019, Neuropharmacology.

Activation of adenosine A2A receptors in the olfactory tubercle promotes sleep in rodents

S. Schiffmann, Zhi-Li Huang, A. de Kerchove d’Exaerde, 2019, Neuropharmacology.

Mesencephalic dopamine neurons are essential for modafinil‐induced arousal

Zhi-Li Huang, Hui Dong, Yan-fei Yang, 2021, British journal of pharmacology.

Signaling mechanism underlying the histamine‐modulated action of hypoglossal motoneurons

Zhi-Li Huang, W. Qu, Yan-Jia Luo, 2016, Journal of neurochemistry.

Interleukin-1β induces sleep independent of prostaglandin D2 in rats and mice

Y. Urade, Zhi-Li Huang, A. Takeuchi, 2017, Neuroscience.

Histaminergic role in sleep-wake cycle of orexin, adenosine, and prostaglandin E2 and D2

Y. Urade, Zhi-Li Huang, O. Hayaishi, 2004 .

GABAergic neurons in the rostromedial tegmental nucleus are essential for rapid eye movement sleep suppression

Zhi-Li Huang, W. Qu, Ze-Ka Chen, 2022, Nature Communications.

Fasting activated histaminergic neurons and enhanced arousal effect of caffeine in mice

W. Qu, Yohko Takata, Xu Wu, 2015, Pharmacology Biochemistry and Behavior.

Paeoniflorin exerts analgesic and hypnotic effects via adenosine A1 receptors in a mouse neuropathic pain model

Zhi-Li Huang, W. Qu, Tian-xiao Wang, 2015, Psychopharmacology.

Lesions of suprachiasmatic nucleus modify sleep structure but do not alter the total amount of daily sleep in rats

Zhi-Li Huang, W. Qu, X. Xu, 2012 .

Ethanol Induces Sedation and Hypnosis via Inhibiting Histamine Release in Mice

Wei Xu, W. Qu, Tian-xiao Wang, 2019, Neurochemical Research.

Repeated sleep restriction in adolescent rats altered sleep patterns and impaired spatial learning/memory ability.

Zhi-Li Huang, M. Yao, W. Qu, 2012, Sleep.

Magnolol, a major bioactive constituent of the bark of Magnolia officinalis, exerts antiepileptic effects via the GABA/benzodiazepine receptor complex in mice

Y. Urade, Zhi-Li Huang, W. Qu, 2011, British journal of pharmacology.

Arousal effect of orexin A depends on activation of the histaminergic system

Y. Urade, Zhi-Li Huang, O. Hayaishi, 2001, Proceedings of the National Academy of Sciences of the United States of America.

A mouse model mimicking human first night effect for the evaluation of hypnotics

Y. Urade, Zhi-Li Huang, W. Qu, 2014, Pharmacology Biochemistry and Behavior.

Genistein induces non-rapid eye movement sleep in mice

M. Qiu, Zhi-Li Huang, W. Qu, 2012 .

Medial Parabrachial Nucleus Is Essential in Controlling Wakefulness in Rats

Jun Lu, Zhi-Li Huang, Hui Dong, 2021, Frontiers in Neuroscience.

Basal Forebrain Cholinergic Neurons Primarily Contribute to Inhibition of Electroencephalogram Delta Activity, Rather Than Inducing Behavioral Wakefulness in Mice

W. Guo, Jun Lu, Zhi-Li Huang, 2016, Neuropsychopharmacology.

Melatonin supplementation in the subacute phase after ischemia alleviates postischemic sleep disturbances in rats

M. Qiu, Zhi-Li Huang, F. Sun, 2021, Brain and behavior.

Glutamate Activates the Histaminergic Tuberomammillary Nucleus and Increases Wakefulness in Rats

Zhi-Li Huang, Hui Dong, W. Qu, 2019, Neuroscience.

The rostromedial tegmental nucleus is essential for non-rapid eye movement sleep

Wei-Min Qu, Yu-Qiang Ding, Zhi-Li Huang, 2018, PLoS biology.

Adenosine A2A receptors in the olfactory bulb suppress rapid eye movement sleep in rodents

S. Schiffmann, Zhi-Li Huang, W. Qu, 2016, Brain Structure and Function.

Sleep Deprivation Disturbs Immune Surveillance and Promotes the Progression of Hepatocellular Carcinoma

Yuye Zhang, W. Qu, Chunmin Liang, 2021, Frontiers in Immunology.

Piromelatine exerts antinociceptive effect via melatonin, opioid, and 5HT1A receptors and hypnotic effect via melatonin receptors in a mouse model of neuropathic pain

Y. Urade, Zhi-Li Huang, M. Laudon, 2014, Psychopharmacology.

Roles of Adrenergic α1 and Dopamine D1 and D2 Receptors in the Mediation of the Desynchronization Effects of Modafinil in a Mouse EEG Synchronization Model

Y. Urade, Zhi-Li Huang, W. Qu, 2013, PloS one.

Dopamine Is Involved in Food-Anticipatory Activity in Mice

Y. Urade, Zhi-Li Huang, W. Qu, 2012, Journal of biological rhythms.

Essential Role of Dopamine D2 Receptor in the Maintenance of Wakefulness, But Not in Homeostatic Regulation of Sleep, in Mice

Wei-Min Qu, Xin-Hong Xu, Yoshihiro Urade, 2010, The Journal of Neuroscience.

D1/D2 receptor-targeting L-stepholidine, an active ingredient of the Chinese herb Stephonia, induces non-rapid eye movement sleep in mice

M. Qiu, Y. Urade, Zhi-Li Huang, 2009, Pharmacology Biochemistry and Behavior.

Dopaminergic D1 and D2 Receptors Are Essential for the Arousal Effect of Modafinil

Y. Urade, N. Matsumoto, Zhi-Li Huang, 2008, The Journal of Neuroscience.

Essential Roles of GABA Transporter-1 in Controlling Rapid Eye Movement Sleep and in Increased Slow Wave Activity after Sleep Deprivation

Y. Urade, Zhi-Li Huang, Fang Huang, 2013, PloS one.

Extracellular histamine level in the frontal cortex is positively correlated with the amount of wakefulness in rats

Y. Urade, Zhi-Li Huang, M. Yao, 2004, Neuroscience Research.

Adenosine and P1 receptors: Key targets in the regulation of sleep, torpor, and hibernation

Zhi-Li Huang, W. Qu, M. Lazarus, 2023, Frontiers in Pharmacology.

Morphine Inhibits Sleep-Promoting Neurons in the Ventrolateral Preoptic Area Via Mu Receptors and Induces Wakefulness in Rats

Y. Urade, Zhi-Li Huang, W. Qu, 2013, Neuropsychopharmacology.

Arousal Effect of Caffeine Depends on Adenosine A2A Receptors in the Shell of the Nucleus Accumbens

Raphaelle Winsky-Sommerer, Wei-Min Qu, Yoshihiro Urade, 2011, The Journal of Neuroscience.

The Mutual Interaction Between Sleep and Epilepsy on the Neurobiological Basis and Therapy

Zhi-Li Huang, W. Qu, Yi-Qun Wang, 2017, Current neuropharmacology.

Red light at intensities above 10 lx alters sleep–wake behavior in mice

Wei-Min Qu, Zhi-Li Huang, W. Qu, 2016, Light: Science & Applications.

Effects of intraperitoneal Ringer's lactate instillation and infusion on postsurgical adhesion formation.

T. Tulandi, W. Qu, K. Chan, 1995, Journal of gynecologic surgery.

Gelsemine alleviates both neuropathic pain and sleep disturbance in partial sciatic nerve ligation mice

Zhi-Li Huang, W. Qu, Yadong Li, 2015, Acta Pharmacologica Sinica.

Dominant localization of prostaglandin D receptors on arachnoid trabecular cells in mouse basal forebrain and their involvement in the regulation of non-rapid eye movement sleep

T. Kaneko, S. Narumiya, Y. Urade, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Altered sleep-wake characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice.

Wei-Min Qu, Yoshihiro Urade, Y. Urade, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice

S. Schiffmann, Y. Urade, Zhi-Li Huang, 2017, Nature Communications.

Safranal Enhances Non‐Rapid Eye Movement Sleep in Pentobarbital‐Treated Mice

Y. Urade, Zhi-Li Huang, W. Qu, 2012, CNS neuroscience & therapeutics.

Drug delivery through a chronically implanted stomach catheter improves efficiency of evaluating wake-promoting components

Y. Urade, N. Matsumoto, Zhi-Li Huang, 2008, Journal of Neuroscience Methods.

Saikosaponin a promotes sleep by decreasing neuronal activities in the lateral hypothalamus

Zhi-Li Huang, Wen Zhang, W. Qu, 2021, Journal of sleep research.

Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine

B. Fredholm, Y. Urade, Zhi-Li Huang, 2005, Nature Neuroscience.

Parasubthalamic calretinin neurons modulate wakefulness associated with exploration in male mice

Zhi-Li Huang, W. Qu, M. Lazarus, 2023, Nature communications.

Modafinil exerts a dose-dependent antiepileptic effect mediated by adrenergic α1 and histaminergic H1 receptors in mice

M. Qiu, M. Yao, W. Qu, 2007, Neuropharmacology.

Symposia Abstracts

Lisa Y. M. Chuah, P. K. Banerjee, J. Siegel, 2005 .

Adenosine A2A receptor mediates hypnotic effects of ethanol in mice

Zhi-Li Huang, Hui Dong, W. Qu, 2017, Scientific Reports.

Ventral pallidal GABAergic neurons control wakefulness associated with motivation through the ventral tegmental pathway

Zhi-Li Huang, W. Qu, Y. Chérasse, 2020, Molecular Psychiatry.

Lesion of intergeniculate leaflet GABAergic neurons attenuates sleep in mice exposed to light.

Zhi-Li Huang, W. Xu, Hui Dong, 2019, Sleep.

Superior Colliculus GABAergic Neurons Are Essential for Acute Dark Induction of Wakefulness in Mice

Zhi-Li Huang, W. Qu, Wen-Ying Liu, 2019, Current Biology.

Nucleus accumbens controls wakefulness by a subpopulation of neurons expressing dopamine D1 receptors

Zhi-Li Huang, Juan Wang, W. Qu, 2018, Nature Communications.

Ethanol inhibits histaminergic neurons in mouse tuberomammillary nucleus slices via potentiating GABAergic transmission onto the neurons at both pre- and postsynaptic sites

Y. Yanagawa, Zhi-Li Huang, W. Qu, 2016, Acta Pharmacologica Sinica.

Roles of adenosine and its receptors in sleep-wake regulation.

Zhi-Li Huang, W. Qu, Ze Zhang, 2014, International review of neurobiology.

Honokiol promotes non‐rapid eye movement sleep via the benzodiazepine site of the GABAA receptor in mice

Y. Urade, Zhi-Li Huang, W. Qu, 2012, British journal of pharmacology.

Lipocalin-type prostaglandin D synthase/beta-trace is a major amyloid beta-chaperone in human cerebrospinal fluid.

Y. Urade, Zhi-Li Huang, I. Mohri, 2007, Proceedings of the National Academy of Sciences of the United States of America.

The Neurobiological Mechanisms and Treatments of REM Sleep Disturbances in Depression

Zhi-Li Huang, W. Qu, Yi-Qun Wang, 2015, Current neuropharmacology.

Acute administration of fluoxetine normalizes rapid eye movement sleep abnormality, but not depressive behaviors in olfactory bulbectomized rats

Zhaopeng Tu, Y. Urade, Zhi-Li Huang, 2012, Journal of neurochemistry.

Dopamine D1 and D2 receptors mediate analgesic and hypnotic effects of l-tetrahydropalmatine in a mouse neuropathic pain model

Zhi-Li Huang, W. Qu, Tian-xiao Wang, 2019, Psychopharmacology.

Dopamine D1 and D2 receptors mediate analgesic and hypnotic effects of l-tetrahydropalmatine in a mouse neuropathic pain model

Zhi-Li Huang, W. Qu, Tian-xiao Wang, 2019, Psychopharmacology.

Nucleus accumbens neurons expressing dopamine D1 receptors modulate states of consciousness in sevoflurane anesthesia

Zhi-Li Huang, W. Qu, Wenxiang Li, 2021, Current Biology.

Dysfunctions of the paraventricular hypothalamic nucleus induce hypersomnia in mice

Zhi-Li Huang, W. Qu, Sha Jiang, 2021, eLife.

Dysfunctions of the paraventricular hypothalamic nucleus induce hypersomnia in human and mice

Zhi-Li Huang, W. Qu, Sha Jiang, 2021, bioRxiv.

Case Report: Dysfunction of the Paraventricular Hypothalamic Nucleus Area Induces Hypersomnia in Patients

Zhi-Li Huang, W. Qu, Sha Jiang, 2022, Frontiers in Neuroscience.

High cortical delta power correlates with aggravated allodynia by activating anterior cingulate cortex GABAergic neurons in neuropathic pain mice.

Zhi-Li Huang, W. Xu, Juan Wang, 2019, Pain.

Nucleus accumbens controls wakefulness by a subpopulation of neurons expressing dopamine D1 receptors

Zhi-Li Huang, Juan Wang, W. Qu, 2018, Nature Communications.

Adenosine and Sleep-Wake Regulation: Adenosine and Sleep-Wake Regulation

Zhi-Li Huang, W. Qu, Yu Sun, 2011 .

Magnolol, a major bioactive constituent of the bark of Magnolia officinalis, induces sleep via the benzodiazepine site of GABAA receptor in mice

Y. Urade, Zhi-Li Huang, W. Qu, 2012, Neuropharmacology.

Striatal neurons expressing dopamine D1 receptor promote wakefulness in mice

Zhi-Li Huang, Hui Dong, W. Qu, 2022, Current Biology.

Understanding the Neural Mechanisms of General Anesthesia from Interaction with Sleep–Wake State: A Decade of Discovery

Zhi-Li Huang, W. Qu, Sha Jiang, 2023, Pharmacological Reviews.

Hypnotic activities of Zao Ren An Shen capsule, a traditional Chinese medicine, in an anxiety-like mouse model

Zhi-Li Huang, W. Qu, Tian-xiao Wang, 2020, Sleep and Breathing.

Ablation of olfactory bulb glutamatergic neurons induces depressive-like behaviors and sleep disturbances in mice

Zhi-Li Huang, Hui Dong, W. Qu, 2020, Psychopharmacology.

An adenosine A receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats.

Y. Urade, Zhi-Li Huang, O. Hayaishi, 2005, Journal of neurochemistry.

Adenosine A2A receptor deficiency attenuates the somnogenic effect of prostaglandin D2 in mice

Y. Urade, Zhi-Li Huang, W. Qu, 2017, Acta Pharmacologica Sinica.

Adenosine A2A receptor deficiency attenuates the somnogenic effect of prostaglandin D2 in mice

Y. Urade, Zhi-Li Huang, W. Qu, 2017, Acta Pharmacologica Sinica.

Presynaptic inputs to vasopressin neurons in the hypothalamic supraoptic nucleus and paraventricular nucleus in mice

Zhi-Li Huang, W. Qu, Z. Xiang, 2021, Experimental Neurology.

Oral Delivery of Honokiol Microparticles for Nonrapid Eye Movement Sleep.

J. Guan, C. Zhan, Jun Qian, 2019, Molecular pharmaceutics.

Neural circuitry underlying REM sleep: A review of the literature and current concepts

Zhi-Li Huang, W. Qu, Wen-Ying Liu, 2021, Progress in neurobiology.

Whole-Brain Monosynaptic Inputs to Hypoglossal Motor Neurons in Mice

Zhi-Li Huang, W. Qu, Hui Chen, 2020, Neuroscience Bulletin.

Whole-brain monosynaptic inputs and outputs of glutamatergic neurons of the vestibular nuclei complex in mice

W. Qu, C. Dai, Hao-Hua Wei, 2020, Hearing Research.

Whole-Brain Neural Connectivity to Lateral Pontine Tegmentum GABAergic Neurons in Mice

Miao He, Zhi-Li Huang, Hui Dong, 2019, Front. Neurosci..

Whole-Brain Monosynaptic Afferent Projections to the Cholecystokinin Neurons of the Suprachiasmatic Nucleus

W. Xu, Zhi-Li Huang, W. Qu, 2018, Front. Neurosci..

Projections of nucleus accumbens adenosine A2A receptor neurons in the mouse brain and their implications in mediating sleep-wake regulation

S. Schiffmann, Y. Urade, Zhi-Li Huang, 2013, Front. Neuroanat..

The Role of Nucleus Accumbens Core/Shell in Sleep-Wake Regulation and their Involvement in Modafinil-Induced Arousal

M. Qiu, Jun Lu, Y. Urade, 2012, PloS one.

Striatal adenosine A2A receptor neurons control active-period sleep via parvalbumin neurons in external globus pallidus

S. Schiffmann, Zhi-Li Huang, Hui Dong, 2017, eLife.

Prostaglandin E2 Activates the Histaminergic System via the EP4 Receptor to Induce Wakefulness in Rats

Y. Urade, Zhi-Li Huang, O. Hayaishi, 2003, The Journal of Neuroscience.

Minireview: Sleep regulation in adenosine A2A receptor-deficient mice

Y. Urade, Zhi-Li Huang, O. Hayaishi, 2003, Neurology.

Whole-brain neural connectivity to cholinergic neurons in the nucleus basalis of Meynert.

Zhi-Li Huang, W. Qu, Xiang-Shan Yuan, 2023, Journal of neurochemistry.

Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep

S. Narumiya, Y. Urade, Zhi-Li Huang, 2006, Proceedings of the National Academy of Sciences.

Antinociceptive and hypnotic activities of pregabalin in a neuropathic pain-like model in mice

Zhi-Li Huang, Wei Guo, W. Qu, 2015, Pharmacology Biochemistry and Behavior.

Hypothalamic CRH Neurons Modulate Sevoflurane Anesthesia and The Post-anesthesia Stress Responses

Zhi-Li Huang, W. Qu, Sha Jiang, 2023, bioRxiv.

The Rostromedial Tegmental Nucleus: Anatomical Studies and Roles in Sleep and Substance Addictions in Rats and Mice

T. Jhou, Zhi-Li Huang, W. Qu, 2020, Nature and science of sleep.

Whole‐brain connectivity to the bed nucleus of the stria terminalis calretinin‐expressing interneurons in male mice

Zhi-Li Huang, W. Qu, Lu Wang, 2023, The European journal of neuroscience.

GABA transporter-1 inhibitor NO-711 alters the EEG power spectra and enhances non-rapid eye movement sleep during the active phase in mice

M. Qiu, Y. Urade, Zhi-Li Huang, 2014, European Neuropsychopharmacology.

An Overview of Roles of the Basal Ganglia in Sleep-Wake Regulation

Zhi-Li Huang, W. Qu, Ze Zhang, 2020 .

Control of wakefulness by lateral hypothalamic glutamatergic neurons in male mice

Zhi-Li Huang, W. Qu, Zi-long Liu, 2021, Journal of neuroscience research.

Selection of optimal epoch duration in assessment of rodent sleep-wake profiles

Wei-Min Qu, Xin-Hong Xu, Yoshihiro Urade, 2011 .

Ethanol Induces Sedation and Hypnosis via Inhibiting Histamine Release in Mice

Wei Xu, W. Qu, Tian-xiao Wang, 2019, Neurochemical Research.

Adenosine A2A receptor mediates hypnotic effects of ethanol in mice

Zhi-Li Huang, Hui Dong, W. Qu, 2017, Scientific Reports.

Acute or Chronic Exposure to Corticosterone Promotes Wakefulness in Mice

Zhi-Li Huang, W. Qu, Zhen Yao, 2023, Brain sciences.

W. Qu, Yuan-Yuan Liu, Ze-Ka Chen, 2024, Acta pharmacologica Sinica.

GBA-AAV mitigates sleep disruptions and motor deficits in mice with REM sleep behavior disorder

W. Qu, Fen Wang, W. Xie, 2024, NPJ Parkinson's disease.

Ambient chemical and physical approaches for the modulation of sleep and wakefulness.

W. Qu, Yi-Qun Wang, Weiming Ma, 2024, Sleep medicine reviews.

Sleep disturbance in rodent models and its sex-specific implications

W. Qu, Yuhong Li, Jixuan Zhou, 2024, Neuroscience & Biobehavioral Reviews.