S. Graham

H. Karibe, P. Weinstein, S. Graham, 1994, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

boc-Aspartyl(OMe)-Fluoromethylketone Attenuates Mitochondrial Release of Cytochrome c and Delays Brain Tissue Loss after Traumatic Brain Injury in Rats

Simon C Watkins, P. Kochanek, J. Melick, 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Proteolysis consistent with activation of caspase-7 after severe traumatic brain injury in humans.

Simon C Watkins, P. Kochanek, D. Marion, 2006, Journal of neurotrauma.

The Genetic Control of Ischemic Neuronal Cell Death

R. Hickey, S. Graham, 2003 .

Caspase‐8 expression and proteolysis in human brain after severe head injury

Simon C Watkins, P. Kochanek, D. Marion, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Dimethylsulfoxide (DMSO) treatment reduces infarction volume after permanent focal cerebral ischemia in rats

R. Simon, S. Graham, S. Shimizu, 1997, Neuroscience Letters.

Delayed induction of mild hypothermia to reduce infarct volume after temporary middle cerebral artery occlusion in rats.

H. Karibe, P. Weinstein, S. Graham, 1994, Journal of neurosurgery.

Hypoxic induction of vascular endothelial growth factor (VEGF) protein in astroglial cultures

C. Cobbs, D. Greenberg, Jun Chen, 1998, Brain Research.

Prostaglandin D2 toxicity in primary neurons is mediated through its bioactive cyclopentenone metabolites.

Muzamil Ahmad, S. Poloyac, R. Hickey, 2013, Neurotoxicology.

The role of excitatory neurotransmitters in seizure-induced neuronal injury in rats

R. Simon, K. Tanaka, S. Graham, 1996, Brain Research.

Cannabinoids and Neuroprotection in Global and Focal Cerebral Ischemia and in Neuronal Cultures

K. Jin, R. Simon, D. Greenberg, 1999, The Journal of Neuroscience.

Soluble epoxide hydrolase inhibitor trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is neuroprotective in rat model of ischemic stroke.

S. Hwang, L. Foley, T. Hitchens, 2013, American journal of physiology. Heart and circulatory physiology.

Neuroprotective effects of the glutamate release inhibitor 619C89 in temporary middle cerebral artery occlusion

K. Kawaguchi, S. Graham, 1997, Brain Research.

c-FLIP-L recombinant adeno-associated virus vector infection prevents Fas-mediated but not nerve growth factor withdrawal-mediated cell death in PC12 cells.

Xiao Xiao, S. Graham, M. Rose, 2004, Brain research. Molecular brain research.

Neuroprotective effects of a use-dependent blocker of voltage-dependent sodium channels, BW619C89, in rat middle cerebral artery occlusion.

R. Simon, M. Leach, S. Graham, 1994, The Journal of pharmacology and experimental therapeutics.

Rapid and simultaneous quantitation of prostanoids by UPLC-MS/MS in rat brain.

S. Poloyac, M. Manole, S. Graham, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Opioid receptor antagonist nalmefene stereospecifically inhibits glutamate release during global cerebral ischemia

H. Shimizu, P. Weinstein, A. Faden, 1993, Brain Research.

Intravenous Formulation of N-Hydroxy-N′-(4-n-butyl-2-methylphenyl)formamidine (HET0016) for Inhibition of Rat Brain 20-Hydroxyeicosatetraenoic Acid Formation

S. Poloyac, L. Rohan, S. Graham, 2008, Drug Metabolism and Disposition.

Changes in extracellular amino acid neurotransmitters produced by focal cerebral ischemia

A. Faden, R. Simon, S. Graham, 1990, Neuroscience Letters.

Transient Global Ischemia Triggers Expression of the DNA Damage-Inducible Gene GADD45 in the Rat Brain

R. Simon, Jun Chen, M. Nakayama, 1998, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

The point mutation UCH-L1 C152A protects primary neurons against cyclopentenone prostaglandin-induced cytotoxicity: implications for post-ischemic neuronal injury

B. Day, R. Hickey, J. Chen, 2015, Cell Death and Disease.

Autophagy is Increased after Traumatic Brain Injury in Mice and is Partially Inhibited by the Antioxidant γ-glutamylcysteinyl Ethyl Ester

Simon C Watkins, P. Kochanek, R. Clark, 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Vascular endothelial growth factor expression in transient focal cerebral ischemia in the rat

C. Cobbs, D. Greenberg, Jun Chen, 1998, Neuroscience Letters.

Apoptosis Repressor Genes Bcl-2 and Bcl-x-Long are Expressed in the Rat Brain following Global Ischemia

R. Simon, Jun Chen, M. Nakayama, 1997, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

The cyclooxygenase site, but not the peroxidase site of cyclooxygenase‐2 is required for neurotoxicity in hypoxic and ischemic injury

Jun Chen, Muzamil Ahmad, Y. Tyurina, 2010, Journal of neurochemistry.

Oxidation and cytotoxicity of 6-OHDA are mediated by reactive intermediates of COX-2 overexpressed in PC12 cells

P. Kochanek, A. Sorokin, Y. Tyurina, 2006, Brain Research.

Increased Generation of Cyclopentenone Prostaglandins after Brain Ischemia and Their Role in Aggregation of Ubiquitinated Proteins in Neurons

Muzamil Ahmad, S. Poloyac, R. Hickey, 2013, Neurotoxicity Research.

Increased expression of apoptosis-linked gene 2 (ALG2) in the rat brain after temporary focal cerebral ischemia

K. Jin, R. Simon, D. Greenberg, 2000, Neuroscience.

Cyclooxygenase-2 Activity Following Traumatic Brain Injury in the Developing Rat

Yue-Fang Chang, R. Hickey, P. Adelson, 2007, Pediatric Research.

Diffusion-weighted magnetic resonance imaging during brief focal cerebral ischemia and early reperfusion: evolution of delayed infarction in rats.

J. Mintorovitch, P. Weinstein, S. Graham, 1995, Neurological research.

10 kD mitochondrial matrix heat shock protein mRNA is induced following global brain ischemia in the rat.

P. Kochanek, R. Hickey, S. Graham, 2000, Brain research. Molecular brain research.

Modification of ubiquitin-C-terminal hydrolase-L1 by cyclopentenone prostaglandins exacerbates hypoxic injury

Muzamil Ahmad, S. Poloyac, R. Hickey, 2011, Neurobiology of Disease.

Cyclooxygenases in central nervous system diseases: a special role for cyclooxygenase 2 in neuronal cell death.

R. Hickey, S. Graham, 2003, Archives of neurology.

Alterations in inducible 72‐kDa heat shock protein and the chaperone cofactor BAG‐1 in human brain after head injury

Simon C Watkins, P. Kochanek, D. Marion, 2003, Journal of neurochemistry.

Suppression of Endogenous bcl-2 Expression by Antisense Treatment Exacerbates Ischemic Neuronal Death

Simon C Watkins, R. Simon, S. Graham, 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Induction of heat-shock protein (HSP72) in the cingulate and retrosplenial cortex by drugs that antagonize the effects of excitatory amino acids.

F. Sharp, R. Simon, S. Graham, 1997, Brain research. Molecular brain research.

Altered Expression of the Neuropeptide-Processing Enzyme Carboxypeptidase E in the Rat Brain after Global Ischemia

K. Jin, R. Simon, D. Greenberg, 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Intracerebroventricular Delivery of Recombinant NAMPT Deters Inflammation and Protects Against Cerebral Ischemia

R. Leak, G. Cao, Fenghua Chen, 2019, Translational Stroke Research.

Cyclooxygenase-2 activity contributes to neuronal expression of cyclin D1 after anoxia/ischemia in vitro and in vivo.

S. Graham, M. Rose, Ren Wu Chen, 2004, Brain research. Molecular brain research.

No long-term benefit from hypothermia after severe traumatic brain injury with secondary insult in rats

S. Wisniewski, P. Kochanek, D. Marion, 2000, Critical care medicine.

Adverse cerebral outcomes after coronary bypass surgery. Multicenter Study of Perioperative Ischemia Research Group and the Ischemia Research and Education Foundation Investigators.

M. Kanchuger, M. Newman, N. Nussmeier, 1996, The New England journal of medicine.

Attenuation of postischemic brain hypoperfusion and reperfusion injury by the cyclooxygenase-lipoxygenase inhibitor BW755C.

P. Weinstein, S. Graham, J. Chen, 1995, Journal of neurosurgery.

Reduction of glutamate release and protection against ischemic brain damage by BW 1003C87

R. Gwinn, B. Meldrum, R. Simon, 1992, Brain Research.

A Pyrimidine Derivative, BW 1003C87, Decreases Glutamate Release and Protects Against Ischemic Damage

R. Gwinn, B. Meldrum, R. Simon, 1992 .

Biochemical Changes and Secondary Tissue Injury After Brain and Spinal Cord Ischemia

R. Bakshi, A. Faden, S. Yum, 1992 .

Phosphorylation of HSP27 by Protein Kinase D Is Essential for Mediating Neuroprotection against Ischemic Neuronal Injury

Jun Chen, Suping Wang, G. Cao, 2012, The Journal of Neuroscience.

HSP70 heat shock protein induction following global ischemia in the rat.

F. Sharp, S. Sagar, S. Graham, 1995, Brain research. Molecular brain research.

EDITORIAL

S. Graham, 1998 .

Rosiglitazone attenuates inflammation and CA3 neuronal loss following traumatic brain injury in rats.

C. Dixon, S. Graham, Hao Liu, 2016, Biochemical and biophysical research communications.

Neuronal Cyclooxygenase-2 Activity and Prostaglandins PGE2, PGD2, and PGF2α Exacerbate Hypoxic Neuronal Injury in Neuron-enriched Primary Culture

Jun Chen, R. Hickey, S. Graham, 2008, Neurochemical Research.

Cyclooxygenase-2 expression is induced in rat brain after kainate-induced seizures and promotes neuronal death in CA3 hippocampus

Jun Chen, R. Hickey, K. Kawaguchi, 2005, Brain Research.

A dose-response study of neuroprotection using the AMPA antagonist NBQX in rat focal cerebral ischemia.

R. Simon, S. Graham, J. Lan, 1996, The Journal of pharmacology and experimental therapeutics.

A study of the dose dependency of a glycine receptor antagonist in focal ischemia.

R. Simon, Jing Chen, F. Moroni, 1993, The Journal of pharmacology and experimental therapeutics.

Induction of Caspase-Activated Deoxyribonuclease Activity after Focal Cerebral Ischemia and Reperfusion

Jun Chen, G. Cao, S. Graham, 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

A comparison of the effects of a sodium channel blocker and an NMDA antagonist upon extracellular glutamate in rat focal cerebral ischemia

R. Simon, Jun Chen, S. Graham, 1995, Brain Research.

A dose-response study of dextrorphan in permanent focal ischemia

R. Simon, Jun Chen, S. Graham, 1993, Neuroscience Letters.

N-Methyl-D-Aspartate-Mediated Neurotoxicity Is Associated with Oxygen-Derived Free Radicals**This work is supported in part by NIH grants NS-14543, AG-08938, and NS-25372. The authors wish to thank Julie Weigel for editorial assistance.

C. Epstein, R. Simon, P. Chan, 1995 .

Assessment of Cerebral Blood Flow and CO2 Reactivity after Controlled Cortical Impact by Perfusion Magnetic Resonance Imaging using Arterial Spin-Labeling in Rats

Stephen R. Wisniewski, Donald S. Williams, S. Wisniewski, 1997, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Protein disulfide isomerase as a novel target for cyclopentenone prostaglandins: implications for hypoxic ischemic injury

Sunita Shinde, R. Hickey, G. Uechi, 2015, The FEBS journal.

In vivo transduction of neurons with TAT-UCH-L1 protects brain against controlled cortical impact injury

C. Dixon, S. Graham, Hao Liu, 2017, PloS one.

Fluorocitrate and fluoroacetate effects on astrocyte metabolism in vitro

R. Swanson, S. Graham, 1994, Brain Research.

An Automated Method of Measurement of Intracranial Mechanical Properties

M. Miner, S. Graham, D. L. Drennon, 1983 .

Induction of Caspase-3-Like Protease May Mediate Delayed Neuronal Death in the Hippocampus after Transient Cerebral Ischemia

R. Simon, Jun Chen, S. Graham, 1998, The Journal of Neuroscience.

Biochemical evidence of myocardial injury after severe head trauma

M. Miner, S. Graham, J. Woo, 1982, Critical care medicine.

Regulation of interstitial excitatory amino acid concentrations after cortical contusion injury

P. Kochanek, J. Melick, J. Schiding, 2002, Brain Research.

Increased Generation of Cyclopentenone Prostaglandins after Brain Ischemia and Their Role in Aggregation of Ubiquitinated Proteins in Neurons

Muzamil Ahmad, S. Poloyac, R. Hickey, 2013, Neurotoxicity Research.

Cerebral injury after cardiac surgery: identification of a group at extraordinary risk. Multicenter Study of Perioperative Ischemia Research Group (McSPI) and the Ischemia Research Education Foundation (IREF) Investigators.

M. Kanchuger, M. Newman, D. Mangano, 1999, Stroke.

Intranuclear localization of apoptosis‐inducing factor (AIF) and large scale dna fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite

Simon C Watkins, P. Kochanek, R. Clark, 2002, Journal of neurochemistry.

Reduction of Cognitive and Motor Deficits after Traumatic Brain Injury in Mice Deficient in Poly(ADP-Ribose) Polymerase

P. Kochanek, D. Marion, R. Clark, 1999, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Expression of the Apoptosis‐Effector Gene, Bax, Is Up‐Regulated in Vulnerable Hippocampal CA1 Neurons Following Global Ischemia

R. Simon, Jun Chen, K. Kawaguchi, 1996, Journal of neurochemistry.

bcl-2 is expressed in neurons that survive focal ischemia in the rat.

Jun Chen, R. Simon, P. Chan, 1995, Neuroreport.

Focal ischemia induces expression of the DNA damage-inducible gene GADD45 in the rat brain.

R. Simon, K. Kawaguchi, S. Graham, 1996, Neuroreport.

Stress Proteins and Tolerance to Focal Cerebral Ischemia

R. Simon, Jun Chen, S. Graham, 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Intracellular Bax Translocation after Transient Cerebral Ischemia: Implications for a Role of the Mitochondrial Apoptotic Signaling Pathway in Ischemic Neuronal Death

M. Minami, Jun Chen, G. Cao, 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Programmed Cell Death in Cerebral Ischemia

Jun Chen, S. Graham, 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Cyclooxygenase-2 inhibition prevents delayed death of CA1 hippocampal neurons following global ischemia.

P. Isakson, M. Nakayama, S. Graham, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Hsp27 Protects against Ischemic Brain Injury via Attenuation of a Novel Stress-Response Cascade Upstream of Mitochondrial Cell Death Signaling

Feng Zhang, R. Anne Stetler, Yanqin Gao, 2008, The Journal of Neuroscience.

Introduction to special issue: Neurovascular aging—A driving force for neurological dysfunction in stroke and neurodegenerative diseases

S. Graham, 2017, Ageing Research Reviews.

Life and death in the trash heap: The ubiquitin proteasome pathway and UCHL1 in brain aging, neurodegenerative disease and cerebral Ischemia

S. Graham, Hao Liu, 2017, Ageing Research Reviews.

Kainate induces the expression of the DNA damage-inducible gene, GADD45, in the rat brain

R. Simon, S. Graham, R. A. Stetler, 1997, Neuroscience.

Neuroprotection against focal ischemic brain injury by the peroxisome proliferator‐activated receptor‐γ agonist rosiglitazone

Jun Chen, A. Signore, Suping Wang, 2006, Journal of neurochemistry.

Fas (CD95) May Mediate Delayed Cell Death in Hippocampal CA1 Sector after Global Cerebral Ischemia

K. Jin, X. Mao, R. Simon, 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis

F. Sharp, A. Lu, Jun Chen, 2002, The Journal of Neuroscience.

92 MOLECULAR PATHOPHYSIOLOGY OF STROKE

R. Hickey, S. Graham, 2002 .

bcl-2 Antisense Treatment Prevents Induction of Tolerance to Focal Ischemia in the Rat Brain

Simon C Watkins, R. Simon, S. Graham, 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Bcl-2 family gene products in cerebral ischemia and traumatic brain injury.

R. Clark, Jun Chen, S. Graham, 2000, Journal of neurotrauma.

Limiting Ischemic Injury by Inhibition of Excitatory Amino Acid Release

F. Sharp, R. Simon, Jun Chen, 1993, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Neuroprotection against Focal Ischemic Brain Injury by Inhibition of c-Jun N-Terminal Kinase and Attenuation of the Mitochondrial Apoptosis-Signaling Pathway

Yanqin Gao, Xiao-Ming Yin, Xiao-Ming Yin, 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Bax κ, a novel Bax splice variant from ischemic rat brain lacking an ART domain, promotes neuronal cell death

X. Mao, R. Simon, D. Greenberg, 2001 .

Disruption of Bax protein prevents neuronal cell death but produces cognitive impairment in mice following traumatic brain injury.

P. Kochanek, R. Clark, C. Dixon, 2008, Journal of neurotrauma.

Innate Gender-based Proclivity in Response to Cytotoxicity and Programmed Cell Death Pathway*

Simon C Watkins, P. Kochanek, R. Clark, 2004, Journal of Biological Chemistry.

Oxidative Stress Following Traumatic Brain Injury in Rats

P. Kochanek, P. Quinn, Y. Tyurina, 2000, Journal of neurochemistry.

Induced hyperthermia exacerbates neurologic neuronal histologic damage after asphyxial cardiac arrest in rats*

P. Kochanek, R. Garman, R. Hickey, 2003, Critical care medicine.

Increased S-Nitrosothiols and S-Nitrosoalbumin in Cerebrospinal Fluid after Severe Traumatic Brain Injury in Infants and Children: Indirect Association with Intracranial Pressure

P. Kochanek, H. Bayır, V. Kagan, 2003, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Protective Effect of the 20-HETE Inhibitor HET0016 on Brain Damage after Temporary Focal Ischemia

P. Kochanek, R. Bies, S. Poloyac, 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Heat Shock Proteins Used to Show that Haloperidol Prevents Neuronal Injury Produced by Ketamine, MK801, and Phencyclidine a

F. Sharp, S. Sagar, J. Koistinaho, 1993, Annals of the New York Academy of Sciences.

Neuroprotective Use‐Dependent Blockers of Na+ and Ca2+ Channels Controlling Presynaptic Release of Glutamatea

S. M. Goldin, Jun Chen, G. J. Durant, 1995, Annals of the New York Academy of Sciences.

Molecular Cloning of a Cell Cycle Regulation Gene Cyclin H from Ischemic Rat Brain

R. Simon, Jun Chen, K. Kawaguchi, 1999, Journal of neurochemistry.

Role of UCHL1 in the pathogenesis of neurodegenerative diseases and brain injury

S. Graham, Zhiping Mi, 2023, Ageing Research Reviews.

Genetic disruption of cyclooxygenase‐2 does not improve histological or behavioral outcome after traumatic brain injury in mice

P. Kochanek, C. Dixon, Muzamil Ahmad, 2008, Journal of neuroscience research.

Cloning of a Novel Apaf-1-Interacting Protein: A Potent Suppressor of Apoptosis and Ischemic Neuronal Cell Death

R. Simon, F. Sun, Jun Chen, 2004, The Journal of Neuroscience.

Translocation of Apoptosis-Inducing Factor in Vulnerable Neurons after Transient Cerebral Ischemia and in Neuronal Cultures after Oxygen-Glucose Deprivation

R. Clark, F. Sun, Jun Chen, 2003, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Caspase-Activated DNase/DNA Fragmentation Factor 40 Mediates Apoptotic DNA Fragmentation in Transient Cerebral Ischemia and in Neuronal Cultures

Xiao-Ming Yin, R. Simon, Jun Chen, 2001, The Journal of Neuroscience.

In Situ Detection of Neuronal DNA Strand Breaks Using the Klenow Fragment of DNA Polymerase I Reveals Different Mechanisims of Neuron Death After Global Cerebral Ischemia

R. Simon, Jun Chen, S. Graham, 1999, Journal of neurochemistry.

Critical Role of Calpain I in Mitochondrial Release of Apoptosis-Inducing Factor in Ischemic Neuronal Injury

R. Clark, Xiao-Ming Yin, A. Liou, 2007, The Journal of Neuroscience.

Intra-mitochondrial Poly(ADP-ribosylation) Contributes to NAD+ Depletion and Cell Death Induced by Oxidative Stress*

Simon C Watkins, P. Kochanek, Y. Han, 2003, The Journal of Biological Chemistry.

Cloning and Characterization of Rat Caspase-9: Implications for a Role in Mediating Caspase-3 Activation and Hippocampal Cell Death after Transient Cerebral Ischemia

Jun Chen, G. Cao, S. Graham, 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Regulation of interstitial excitatory amino acid concentrations after cortical contusion injury

P. Kochanek, J. Melick, J. Schiding, 2002, Brain Research.

Novel therapies for combating chronic neuropathological sequelae of TBI

C. Dixon, M. Ikonomovic, E. Abrahamson, 2019, Neuropharmacology.

Expression of the RNA‐binding protein TIAR is increased in neurons after ischemic cerebral injury

X. Mao, R. Simon, D. Greenberg, 2000, Journal of neuroscience research.

Mitochondrial Targets for Stroke: Focusing Basic Science Research Toward Development of Clinically Translatable Therapeutics

L. Wechsler, Jun Chen, S. Graham, 2009, Stroke.

Paths to Successful Translation of New Therapies for Severe Traumatic Brain Injury in the Golden Age of Traumatic Brain Injury Research: A Pittsburgh Vision.

Christopher M. Horvat, S. Wisniewski, D. L. Taylor, 2020, Journal of neurotrauma.

Topical Reviews Mitochondrial Targets for Stroke Focusing Basic Science Research toward Development of Clinically Translatable Therapeutics past Clinical Strategies Reperfusion Therapy Antiexcitotoxicity Therapy Mitochondrial Stroke Targets Downstream Mitochondrial Death Effectors Direct Targets of

L. Wechsler, Jun Chen, S. Graham, 2009 .

Delayed, spontaneous hypothermia reduces neuronal damage after asphyxial cardiac arrest in rats

C. Callaway, P. Kochanek, P. Safar, 2000, Critical care medicine.

Hypothermia and Hyperthermia in Children After Resuscitation From Cardiac Arrest

P. Kochanek, P. Safar, R. Hickey, 2000, Pediatrics.

Hypoperfusion-related cerebral ischemia and cardiac left ventricular systolic dysfunction.

S. Graham, P. Pullicino, D. Smajlović, 2001, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

Increased adenosine in cerebrospinal fluid after severe traumatic brain injury in infants and children: Association with severity of injury and excitotoxicity

S. Wisniewski, P. Kochanek, D. Marion, 2001, Critical care medicine.

N-Acetylaspartate as an in vivo Marker of Neuronal Viability in Kainate-Induced Status Epilepticus: 1H Magnetic Resonance Spectroscopic Imaging

T. Ebisu, W. Rooney, A. Maudsley, 1994, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Mild intraischemic hypothermia suppresses consumption of endogenous antioxidants after temporary focal ischemia in rats

H. Karibe, P. Weinstein, P. Chan, 1994, Brain Research.

Glucose Can Fuel Glutamate Uptake in Ischemic Brain

R. Swanson, Jing Chen, S. Graham, 1994, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Transgenic mice that overexpress the anti-apoptotic Bcl-2 protein have improved histological outcome but unchanged behavioral outcome after traumatic brain injury

P. Kochanek, R. Clark, C. Dixon, 2006, Brain Research.

Mutation of a Ubiquitin Carboxy Terminal Hydrolase L1 Lipid Binding Site Alleviates Cell Death, Axonal Injury, and Behavioral Deficits After Traumatic Brain Injury in Mice

C. Dixon, S. Graham, Hao Liu, 2021, Neuroscience.

Role of UCHL1 in axonal injury and functional recovery after cerebral ischemia

N. Povysheva, G. Barrionuevo, Fenghua Chen, 2019, Proceedings of the National Academy of Sciences.

Modification of ubiquitin C-terminal hydrolase L1 by reactive lipid species: role in neural regeneration and diseases of aging

S. Graham, 2016, Neural regeneration research.

MR spectroscopic imaging and diffusion‐weighted MRI for early detection of kainate‐induced status epilepticus in the rat

M. Weiner, W. Rooney, A. Maudsley, 1996, Magnetic resonance in medicine.

Expression of the proto-oncogene bcl-2 is increased in the rat brain following kainate-induced seizures.

R. Simon, S. Graham, R. A. Stetler, 1996, Restorative neurology and neuroscience.