J. Frade

发表

Somatic tetraploidy in specific chick retinal ganglion cells induced by nerve growth factor

S. M. Morillo, Pedro Escoll, A. De La Hera, 2009, Proceedings of the National Academy of Sciences.

Pathological Aspects of Neuronal Hyperploidization in Alzheimer’s Disease Evidenced by Computer Simulation

J. Frade, M. Valero, E. Barrio-Alonso, 2020, Frontiers in Genetics.

E2F4 as a single multifactorial target against Alzheimer’s disease

J. Frade, N. López-Sánchez, Morgan Ramón-Landreau, 2020, bioRxiv.

Neuronal tetraploidy in Alzheimer and aging

J. Frade, N. López-Sánchez, 2017, Aging.

Lateral inhibition and neurogenesis: novel aspects in motion.

M. Ibañes, S. Ares, Pau Formosa-Jordan, 2013, International Journal of Developmental Biology.

The zinc finger protein NRIF interacts with the neurotrophin receptor p 75 NTR and participates in programmed cell death

Y. Barde, E. Casademunt, J. Frade, 2013 .

The zinc finger protein NRIF interacts with the neurotrophin receptor p75NTR and participates in programmed cell death

Yves-Alain Barde, Bruce D. Carter, Y. Barde, 1999 .

Insulin-like growth factor-I stimulates neurogenesis in chick retina by regulating expression of the alpha 6 integrin subunit.

P. Bovolenta, H. Rohrer, A. Rodríguez-Tébar, 1996, Development.

Neurotrophin-3 Antibodies Disrupt the Normal Development of the Chick Retina

P. Bovolenta, A. Rodríguez-Tébar, Y. Barde, 1996, The Journal of Neuroscience.

Developmentally regulated vitronectin influences cell differentiation, neuron survival and process outgrowth in the developing chicken retina

J. Frade, E. Martí, J. -. Marti´nez-Morales, 1995, Neuroscience.

The neurotrophin receptors TrkA and TrkC but not TrkB cause neuronal death

Y. Barde, V. Nikoletopoulou, M. Bibel, 2010 .

Axonal and Myelin Neuroprotection by the Peptoid BN201 in Brain Inflammation

E. Giralt, L. Steinman, I. Pertsovskaya, 2019, Neurotherapeutics.

Unscheduled re-entry into the cell cycle induced by NGF precedes cell death in nascent retinal neurones.

J. Frade, José María Frade, J. M. Frade, 2000, Journal of cell science.

Nerve Growth Factor-Induced Cell Cycle Reentry in Newborn Neurons Is Triggered by p38MAPK-Dependent E2F4 Phosphorylation

S. M. Morillo, J. Frade, Erika P Abanto, 2012, Molecular and Cellular Biology.

Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord.

Y. Barde, J. Frade, 1999, Development.

p27Kip1 participates in the regulation of endoreplication in differentiating chick retinal ganglion cells

J. Frade, M. Ovejero-Benito, M. C. Ovejero-Benito, 2015, Cell cycle.

Heterogeneity Among Neuroepithelial Cells in the Chick Retina Revealed by Immunostaining with Monoclonal Antibody PM1

J. Frade, C. Hernández-Sánchez, Enrique J. La Rosa, 1994, The European journal of neuroscience.

NRAGE and the cycling side of the neurotrophin receptor p75

J. Frade, 2000, Trends in Neurosciences.

E2F4DN Transgenic Mice: A Tool for the Evaluation of E2F4 as a Therapeutic Target in Neuropathology and Brain Aging

J. Frade, N. López-Sánchez, Morgan Ramón-Landreau, 2022, International journal of molecular sciences.

Lengthening of G2/mitosis in cortical precursors from mice lacking β-amyloid precursor protein

U. Müller, J. Frade, N. López-Sánchez, 2005, Neuroscience.

Nuclear Translocation of the p75 Neurotrophin Receptor Cytoplasmic Domain in Response to Neurotrophin Binding

J. Frade, 2005, The Journal of Neuroscience.

Strand-specific CpG hemimethylation, a novel epigenetic modification functional for genomic imprinting

J. Frade, N. López-Sánchez, Iris Patiño-Parrado, 2017, Nucleic acids research.

Control of neuronal ploidy during vertebrate development.

J. Frade, N. López-Sánchez, M. C. Ovejero-Benito, 2011, Results and problems in cell differentiation.

Sortilin Participates in Light-dependent Photoreceptor Degeneration in Vivo

P. de la Villa, J. Frade, D. Martín-Oliva, 2012, PloS one.

Neurotrophins and other growth factors in the generation of retinal neurons

P. Bovolenta, J. Frade, A. Rodríguez‐Tébar, 1999, Microscopy research and technique.

Induction of cell death by endogenous nerve growth factor through its p75 receptor

Y. Barde, J. Frade, A. Rodríguez‐Tébar, 1996, Nature.

A Mutant Variant of E2F4 Triggers Multifactorial Therapeutic Effects in 5xFAD Mice

J. Frade, N. López-Sánchez, Morgan Ramón-Landreau, 2022, Molecular Neurobiology.

Neuronal cell cycle: the neuron itself and its circumstances

J. Frade, M. C. Ovejero-Benito, 2015, Cell cycle.

Genomic Mosaicism in Neurons and Other Cell Types

F. Gage, J. Frade, 2017, Neuromethods.

Neuronal Injury External to the Retina Rapidly Activates Retinal Glia, Followed by Elevation of Markers for Cell Cycle Re-Entry and Death in Retinal Ganglion Cells

P. D'Onofrio, P. Koeberle, Mark M. Magharious, 2014, PloS one.

Cell cycle control of Notch signaling and the functional regionalization of the neuroepithelium during vertebrate neurogenesis.

E. Cisneros, M. Latasa, J. Frade, 2009, The International journal of developmental biology.

Primary neurons can enter M-phase

J. Garrido, J. Frade, E. Barrio-Alonso, 2019, Scientific Reports.

Checkpoint signaling abrogation after cell cycle reentry reveals that differentiated neurons are mitotic cells

J. Garrido, J. Frade, E. Barrio-Alonso, 2018, bioRxiv.

Control of the cell cycle by neurotrophins: lessons from the p75 neurotrophin receptor.

J. Frade, N. López-Sánchez, 2002, Histology and histopathology.

NGF/P75 in Cell Cycle and Tetraploidy

Claudia Rodríguez-Ruiz, J. Frade, N. López-Sánchez, 2014 .

Flow Cytometric Quantification, Isolation, and Subsequent Epigenetic Analysis of Tetraploid Neurons

J. Frade, N. López-Sánchez, Iris Patiño-Parrado, 2017 .

A novel hypothesis for Alzheimer disease based on neuronal tetraploidy induced by p75NTR

J. Frade, N. López-Sánchez, 2010, Cell cycle.

Mitochondrial c-Jun NH2-Terminal Kinase Prevents the Accumulation of Reactive Oxygen Species and Reduces Necrotic Damage in Neural Tumor Cells that Lack Trophic Support

José Rodríguez, J. Frade, N. López-Sánchez, 2007, Molecular Cancer Research.

Brain-Derived Neurotrophic Factor-Dependent cdk1 Inhibition Prevents G2/M Progression in Differentiating Tetraploid Neurons

J. Frade, M. C. Ovejero-Benito, 2013, PloS one.

Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not

Y. Barde, V. Nikoletopoulou, M. Bibel, 2010, Nature.

Casemix, management, and mortality of patients receiving emergency neurosurgery for traumatic brain injury in the Global Neurotrauma Outcomes Study: a prospective observational cohort study.

Madeleine de Lotbiniere-Bassett, Ting Ting Jiang, Paulo H. R. Nakashima, 2022, The Lancet. Neurology.

Interkinetic nuclear movement in the vertebrate neuroepithelium: encounters with an old acquaintance.

J. Frade, 2002, Progress in brain research.

Neuronal tetraploidization in the cerebral cortex correlates with reduced cognition in mice and precedes and recapitulates Alzheimer's-associated neuropathology

A. Rábano, J. Frade, J. Trejo, 2017, Neurobiology of Aging.

Genetic Evidence for p75NTR-Dependent Tetraploidy in Cortical Projection Neurons from Adult Mice

J. Frade, N. López-Sánchez, 2013, The Journal of Neuroscience.

Nerve growth factor: two receptors, multiple functions

Y. Barde, J. Frade, 1998, BioEssays : news and reviews in molecular, cellular and developmental biology.

E2F4-Based Gene Therapy Mitigates the Phenotype of the Alzheimer’s Disease Mouse Model 5xFAD

J. Frade, N. López-Sánchez, Morgan Ramón-Landreau, 2021, Neurotherapeutics.

Cell cycle reentry triggers hyperploidization and synaptic dysfunction followed by delayed cell death in differentiated cortical neurons

G. Perea, J. Frade, E. Barrio-Alonso, 2018, Scientific Reports.

Somatic tetraploidy in vertebrate neurons

J. Frade, 2010, Communicative & integrative biology.

Neuronal and astrocytic tetraploidy is increased in drug‐resistant epilepsy

J. Frade, A. Sanz-García, P. Pulido, 2022, medRxiv.

Microglia-Derived Nerve Growth Factor Causes Cell Death in the Developing Retina

Y. Barde, J. Frade, 1998, Neuron.

Axonal and Myelin Neuroprotection by the Peptoid BN201 in Brain Inflammation

E. Giralt, L. Steinman, I. Pertsovskaya, 2019, Neurotherapeutics.

Introduction of macarpine as a novel cell‐permeant DNA dye for live cell imaging and flow cytometry sorting

J. Frade, N. López-Sánchez, I. Slaninová, 2016, Biology of the cell.

Stabilization of Dll1 mRNA by Elavl1/HuR in neuroepithelial cells undergoing mitosis

Dimitris L. Kontoyiannis, E. Cisneros, D. Kontoyiannis, 2011, Molecular biology of the cell.

Laminin-1 selectively stimulates neuron generation from cultured retinal neuroepithelial cells.

J. Frade, J. Martínez-Morales, A. Rodríguez‐Tébar, 1996, Experimental cell research.

The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death.

Y. Barde, E. Casademunt, J. Frade, 1999, The EMBO journal.

Control of early cell death by BDNF in the chick retina.

P. Bovolenta, J. Frade, J. Martínez-Morales, 1997, Development.

Regulation of neuronal differentiation at the neurogenic wavefront

M. Ibañes, Pau Formosa-Jordan, J. Frade, 2012, Development.

Instability of Notch1 and Delta1 mRNAs and reduced Notch activity in vertebrate neuroepithelial cells undergoing S-phase

E. Cisneros, M. Latasa, J. Frade, 2008, Molecular and Cellular Neuroscience.

Neurotrophins and their p75 receptor.

Y. Barde, C. Kaltschmidt, J. Frade, 1996, Cold Spring Harbor symposia on quantitative biology.

Regulation of neuronal differentiation at the neurogenic wavefront

M. Ibañes, Pau Formosa-Jordan, J. Frade, 2012, Development.

Regulation of neuronal differentiation at the neurogenic

M. Ibañes, Pau Formosa-Jordan, J. Frade, 2012 .

Monocyte chemoattractant protein-1-induced CCR2B receptor desensitization mediated by the G protein-coupled receptor kinase 2.

C. Martínez-A, M. Mellado, J. Frade, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Role of neurotrophins in the control of neural development: Neurotrophin-3 promotes both neuron differentiation and survival of cultured chick retinal cells

E. J. Rosa, J. Frade, A. Rodri´guez-Te´bar, 1994, Neuroscience.

Cell cycle reentry triggers hyperploidization and synaptic dysfunction followed by delayed cell death in differentiated cortical neurons

G. Perea, J. Frade, C. C. Walton, 2018, Scientific Reports.

Functional expression of chemokine receptor 2 by normal human eosinophils.

A. Kaser, M. Mellado, J. Frade, 2001, The Journal of allergy and clinical immunology.

Introduction of macarpine as a novel cell‐permeant DNA dye for live cell imaging and flow cytometry sorting

J. Frade, N. López-Sánchez, I. Slaninová, 2016, Biology of the cell.

Lateral inhibition and neurogenesis: novel aspects in motion.

M. Ibañes, Pau Formosa-Jordan, J. Frade, 2013, The International journal of developmental biology.