C. Leach

发表

Respiratory Tract Deposition of HFA-Beclomethasone and HFA-Fluticasone in Asthmatic Patients.

J. McDonald, C. Leach, P. Kuehl, 2016, Journal of aerosol medicine and pulmonary drug delivery.

Two-dimensional and three-dimensional imaging show ciclesonide has high lung deposition and peripheral distribution: a nonrandomized study in healthy volunteers.

A. Drollmann, W. Wurst, C. Leach, 2006, Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine.

Improved delivery of inhaled steroids to the large and small airways.

C. Leach, 1998, Respiratory medicine.

A novel breath actuated device (Autohaler) consistently actuates during the early phase of inspiration.

H. Kaiser, C. Leach, P. Marshik, 1995, Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine.

Alternative propellant aerosol delivery systems.

H. Smyth, C. Leach, 2005, Critical reviews in therapeutic drug carrier systems.

Inhalation of Human Insulin Is Associated with Improved Insulin Action Compared with Subcutaneous Injection and Endogenous Secretion in Dogs

D. Edgerton, A. Cherrington, C. Hobbs, 2006, Journal of Pharmacology and Experimental Therapeutics.

Spacer inhalation technique and deposition of extrafine aerosol in asthmatic children

P. N. Souëf, C. Leach, S. Devadason, 2006, European Respiratory Journal.

Inhaled Insulin Is Associated with Prolonged Enhancement of Glucose Disposal in Muscle and Liver in the Canine

A. del Parigi, D. Edgerton, A. Cherrington, 2009, Journal of Pharmacology and Experimental Therapeutics.

Inhalation of insulin in dogs: assessment of insulin levels and comparison to subcutaneous injection.

D. Edgerton, A. Cherrington, C. Hobbs, 2004, Diabetes.

Inhalation of insulin (Exubera) is associated with augmented disposal of portally infused glucose in dogs.

D. Edgerton, A. Cherrington, C. Hobbs, 2005, Diabetes.

Characterization of respiratory deposition of fluticasone-salmeterol hydrofluoroalkane-134a and hydrofluoroalkane-134a beclomethasone in asthmatic patients.

J. McDonald, L. Ketai, J. Norenberg, 2012, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Lung deposition of hydrofluoroalkane-134a beclomethasone is greater than that of chlorofluorocarbon fluticasone and chlorofluorocarbon beclomethasone : a cross-over study in healthy volunteers.

C. Leach, R. Boudreau, B. E. Hasselquist, 2002, Chest.

Mometasone and beclomethasone comparison article observations.

C. Leach, P. Lesouef, 2006, Chest.

Relevance of radiolabeled steroid inhalation studies to clinical outcomes.

C. Leach, 1998, Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine.

Effect of formulation parameters on hydrofluoroalkane-beclomethasone dipropionate drug deposition in humans.

C. Leach, 1999, The Journal of allergy and clinical immunology.

Antibody response to trimellityl hemoglobin in trimellitic anhydride-induced lung injury.

R. Patterson, C. Zeiss, C. Leach, 1988, The Journal of allergy and clinical immunology.

Levels and specificity of antibody in bronchoalveolar lavage (BAL) and serum in an animal model of trimellitic anhydride-induced lung injury.

M. J. Chandler, R. Patterson, C. Zeiss, 1987, The Journal of allergy and clinical immunology.

A model of immunologic lung injury induced by trimellitic anhydride inhalation: antibody response.

M. J. Chandler, C. Zeiss, C. Leach, 1987, The Journal of allergy and clinical immunology.

Nasal Deposition of HFA-Beclomethasone, Aqueous Fluticasone Propionate and Aqueous Mometasone Furoate in Allergic Rhinitis Patients.

J. McDonald, C. Leach, P. Kuehl, 2015, Journal of aerosol medicine and pulmonary drug delivery.

Toxicology of Propellants

C. Leach, 1997 .

Pulmonary Cellular and Antibody Response to Trlmellltlc Anhydride Inhalation

C. Zeiss, C. Leach, P. Garvin, 1989 .

Safety, Tolerance and Pharmacokinetics of HFA-152a in Healthy Volunteers

C. Leach, P. Kuehl, S. Corr, 2022 .

Inhalation of Human Insulin (Exubera) Augments the Efficiency of Muscle Glucose Uptake In Vivo

D. Edgerton, A. Cherrington, P. Williams, 2006, Diabetes.

Reply to Drs Newman and Pitcairn

C. Leach, 1999 .

Targeting inhaled steroids.

C. Leach, 1998, International journal of clinical practice. Supplement.

Improved airway targeting with the CFC-free HFA-beclomethasone metered-dose inhaler compared with CFC-beclomethasone.

C. Leach, C L Leach, P J Davidson, 1998, The European respiratory journal.

A serial immunologic and histopathologic study of lung injury induced by trimellitic anhydride.

R. Patterson, C. Zeiss, L. Smith, 1988, The American review of respiratory disease.

Evidence of immunologic control of lung injury induced by trimellitic anhydride.

C. Zeiss, C. Leach, H. Ratajczak, 1988, The American review of respiratory disease.

The Generation and Detection of Particulate Aerosols of Trimellitic Anhydride and Trimellitic Acid for Inhalation Exposures

A. Ledbetter, C. Leach, N. Hatoum, 1987 .

Effects of acrolein on macrophage functions in rats.

C. Leach, C. Aranyi, R. Sherwood, 1986, Toxicology letters.

The CFC to HFA transition and its impact on pulmonary drug development.

C. Leach, 2005, Respiratory care.

Generation of Gas and Liquid Hydrocarbon Mixtures from a Single Pressurized Cylinder for Inhalation Exposures

A. Ledbetter, C. Leach, N. Hatoum, 1985 .

Influence of particle size and patient dosing technique on lung deposition of HFA-beclomethasone from a metered dose inhaler.

C. Leach, R. Boudreau, B. E. Hasselquist, 2005, Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine.

A pilot study to assess lung deposition of HFA-beclomethasone and CFC-beclomethasone from a pressurized metered dose inhaler with and without add-on spacers and using varying breathhold times.

G. Colice, C. Leach, Gene L Colice, 2010, Journal of aerosol medicine and pulmonary drug delivery.

Particle size of inhaled corticosteroids: does it matter?

G. Colice, C. Leach, A. Luskin, 2009, The Journal of allergy and clinical immunology.

Biologic Comparison of Inhaled Insulin Formulations: ExuberaTM and Novel Spray-Dried Engineered Particles of Dextran-10

Dan E. Dobry, D. Edgerton, A. Cherrington, 2014, AAPS PharmSciTech.

Approaches and Challenges to Use Freon Propellant Replacements

C. Leach, 1995 .

Biologic Comparison of Inhaled Insulin Formulations: ExuberaTM and Novel Spray-Dried Engineered Particles of Dextran-10

Dan E. Dobry, D. Edgerton, A. Cherrington, 2014, AAPS PharmSciTech.

The pathologic and immunologic response to inhaled trimellitic anhydride in rats.

C. Zeiss, C. Leach, H. Ratajczak, 1987, Toxicology and applied pharmacology.

Inhalation Aspects of Therapeutic Aerosols

C. Leach, 2007, Toxicologic pathology.