B. Shafit-Zagardo

发表

Cytoskeletal Alterations in Human Fetal Astrocytes Induced by Interleukin‐1β

D. Dickson, C. Brosnan, Sunhee C. Lee, 1994, Journal of neurochemistry.

Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR‐155 and miR‐155*

Sunhee C. Lee, B. Shafit-Zagardo, Hyeon-sook Suh, 2011, Glia.

A Novel Microtubule‐Associated Protein‐2 Expressed in Oligodendrocytes in Multiple Sclerosis Lesions

Sunhee C. Lee, B. Shafit-Zagardo, Y. Kress, 1999, Journal of neurochemistry.

Novel microtubule‐associated protein‐2 isoform is expressed early in human oligodendrocyte maturation

P. Davies, Sunhee C. Lee, J. Rockwood, 2000, Glia.

Tumor Necrosis Factor‐Induced Proliferation of Astrocytes from Mature Brain Is Associated with Down‐Regulation of Glial Fibrillary Acidic Protein mRNA

C. Brosnan, K. Selmaj, C. Raine, 1991, Journal of neurochemistry.

The control of reactive oxygen species production by SHP‐1 in oligodendrocytes

B. Shafit-Zagardo, A. Ray, C. Hudson, 2015, Glia.

TMEM106B is increased in Multiple Sclerosis plaques, and deletion causes accumulation of lipid after demyelination

S. Strittmatter, J. Goldman, B. Shafit-Zagardo, 2022, bioRxiv.

Phorbol‐12‐myristate‐13‐acetate (PMA) and inhibitors of protein kinase C alter glial fibrillary acidic protein (GFAP) mRNA levels

B. Shafit-Zagardo, N. Sharma, Kathleen Norman‐O'guin, 1991, Glia.

The Growth Arrest-Specific Gene Product Gas6 Promotes the Survival of Human Oligodendrocytes via a Phosphatidylinositol 3-Kinase-Dependent Pathway

M. Cammer, B. Varnum, F. Mcmorris, 2003, The Journal of Neuroscience.

Binding of Fyn to MAP-2c through an SH3 Binding Domain

P. Davies, B. Shafit-Zagardo, G. Lee, 2001, The Journal of Biological Chemistry.

Expression of Microtubule‐Associated Protein‐2a and Other Novel Microtubule‐Associated Protein‐2 Transcripts in Human Fetal Spinal Cord

B. Shafit-Zagardo, Y. Kress, K. Weidenheim, 1997, Journal of neurochemistry.

Antisense MAP-2 oligonucleotides induce changes in microtubule assembly and neuritic elongation in pre-existing neurites of rat cortical neurons.

B. Shafit-Zagardo, Y. Kress, N. Sharma, 1994, Cell motility and the cytoskeleton.

Suppression of Inflammatory Responses during Myelin Oligodendrocyte Glycoprotein–Induced Experimental Autoimmune Encephalomyelitis Is Regulated by AKT3 Signaling

F. Macian, B. Shafit-Zagardo, Jason G. Weinger, 2013, The Journal of Immunology.

Expression of Glial Fibrillary Acidic Protein and Neurofilament mRNA in Gliosis Induced by Experimental Autoimmune Encephalomyelitis

C. Brosnan, B. Shafit-Zagardo, D. Aquino, 1990, Journal of neurochemistry.

Astrocytes regulate GFAP mRNA levels by cyclic AMP and protein kinase C‐dependent mechanisms

J. Goldman, B. Shafit-Zagardo, A. Kume-Iwaki, 1988, Glia.

Isolation and characterization of cDNA clones encoding epitopes shared with alzheimer neurofibrillary tangles

S. Yen, M. Goldstein, B. Shafit-Zagardo, 1988, Journal of neuroscience research.

Rapid Increases in Glial Fibrillary Acidic Protein mRNA and Protein Levels in the Copper‐Deficient, Brindled Mouse

J. Goldman, B. Shafit-Zagardo, C. Peterson, 1988, Journal of neurochemistry.

Chromosomal localization of the gene for Gaucher disease.

R. Desnick, F. Arredondo-Vega, B. Shafit-Zagardo, 1982, Progress in clinical and biological research.

Assignment of the gene for acid beta-glucosidase to human chromosome 1.

R. Desnick, F. Arredondo-Vega, Moyra J. Smith, 1981, American journal of human genetics.

Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis

P. Davies, B. Shafit-Zagardo, A. Ray, 2020, Journal of neuroinflammation.

UCN‐01 alters phosphorylation of Akt and GSK3β and induces apoptosis in six independent human neuroblastoma cell lines

S. Mani, B. Shafit-Zagardo, B. Parashar, 2004, Journal of neurochemistry.

Genomic structure of human microtubule-associated protein 2 (MAP-2) and characterization of additional MAP-2 isoforms.

J. Albala, C. Garner, B. Shafit-Zagardo, 1995, Proceedings of the National Academy of Sciences of the United States of America.

SignalingEncephalomyelitis Is Regulated by AKT3 Induced Experimental Autoimmune during Myelin Oligodendrocyte Glycoprotein Suppression of Inflammatory Responses

F. Macian, B. Shafit-Zagardo, Jason G. Weinger, 2013 .

Molecular and functional characteristics of MAP-2a: ability of MAP-2a versus MAP-2b to induce stable microtubules in COS cells.

J. Rockwood, B. Shafit-Zagardo, Y. Kress, 1998, Cell motility and the cytoskeleton.

Targeted GAS6 Delivery to the CNS Protects Axons from Damage during Experimental Autoimmune Encephalomyelitis

B. Shafit-Zagardo, Christopher T. Johndrow, A. Ray, 2014, The Journal of Neuroscience.

Identification of the MAP2- and P75-binding domain in the regulatory subunit (RII beta) of type II cAMP-dependent protein kinase. Cloning and expression of the cDNA for bovine brain RII beta.

J. Erlichman, Zhijun Luo, Z. Luo, 1990, The Journal of biological chemistry.

Gas6/Axl Signaling Activates the Phosphatidylinositol 3-Kinase/Akt1 Survival Pathway to Protect Oligodendrocytes from Tumor Necrosis Factorα-Induced Apoptosis

C. Brosnan, Mimi Kim, B. Varnum, 2006, The Journal of Neuroscience.

Akt3-Mediated Protection Against Inflammatory Demyelinating Disease

B. Shafit-Zagardo, Yongwei Zhang, A. Ray, 2019, Front. Immunol..

Human beta-glucosidase: inhibition by sulphates and purification by affinity chromatography on Dextran-sulphate-Sepharose.

B. Turner, B. Shafit-Zagardo, 1981, Biochimica et biophysica acta.

Up-regulation of soluble Axl and Mer receptor tyrosine kinases negatively correlates with Gas6 in established multiple sclerosis lesions.

C. Raine, K. Marsden, B. Shafit-Zagardo, 2009, The American journal of pathology.

Multiple sclerosis: Re-expression of a developmental pathway that restricts oligodendrocyte maturation

C. Brosnan, Sunhee C. Lee, A. Massimi, 2002, Nature Medicine.

Electrophoretic separation of neutral and acid beta-glucosidase isozymes in human tissues.

R. Desnick, B. Shafit-Zagardo, E. Devine, 1980, Biochimica et biophysica acta.

Disruption of the actin network enhances MAP-2c and Fyn-induced process outgrowth.

B. Shafit-Zagardo, S. P. Zamora-León, 2005, Cell motility and the cytoskeleton.

Assignment oftheGeneforAcid/3-Glucosidase toHumanChromosome 1

F. Arredondo-Vega, B. Shafit-Zagardo, 1981 .

Gas6 enhances axonal ensheathment by MBP+ membranous processes in human DRG/OL promyelinating co-cultures

C. Raine, B. Shafit-Zagardo, Hillary Guzik, 2013, ASN neuro.

Human Microtubule‐Associated Protein‐2c Localizes to Dendrites and Axons in Fetal Spinal Motor Neurons

J. Albala, S. Yen, W. Liu, 1995, Journal of neurochemistry.

Making sense of the multiple MAP-2 transcripts and their role in the neuron

B. Shafit-Zagardo, Bridget Shafit-Zagardo, Nellie Kalcheva, 1998, Molecular Neurobiology.

Failure of Neuronal Maturation in Alzheimer Disease Dentate Gyrus

H. Yamamori, I. Grundke‐Iqbal, K. Iqbal, 2008, Journal of neuropathology and experimental neurology.

Fyn Phosphorylates Human MAP-2c on Tyrosine 67*

A. Bresnick, J. Backer, B. Shafit-Zagardo, 2005, Journal of Biological Chemistry.

MAP‐2e, a Novel MAP‐2 Isoform, Is Expressed in Gliomas and Delineates Tumor Architecture and Patterns of Infiltration

Satoshi O. Suzuki, Sunhee C. Lee, R. Kitai, 2002, Journal of neuropathology and experimental neurology.

Distribution and Subcellular Localization of High‐Molecular‐Weight Microtubule‐Associated Protein‐2 Expressing Exon 8 in Brain and Spinal Cord

P. Davies, B. Shafit-Zagardo, Y. Kress, 1997, Journal of neurochemistry.

Localization of Specific Epitopes on Human Microtubule‐Associated Protein 2

J. Albala, B. Shafit-Zagardo, L. Binder, 1994, Journal of neurochemistry.

Characterization of the transcripts encoding two isoforms of human microtubule-associated protein-2 (MAP-2).

J. Albala, B. Shafit-Zagardo, N. Kalcheva, 1993, Gene.

Assay of enzymes of lipid metabolism with colored and fluorescent derivatives of natural lipids.

Y. Barenholz, R. Desnick, S. Gatt, 1981, Methods in enzymology.

KpnI families of long, interspersed repetitive DNAs associated with the human beta-globin gene cluster.

J. Maio, B. Shafit-Zagardo, J. Adams, 1982, Gene.

Transcription of the KpnI families of long interspersed DNAs in human cells

J. Maio, B. Shafit-Zagardo, P. Zavodny, 1983, Nature.

The role of TAM family receptors and ligands in the nervous system: From development to pathobiology

B. Shafit-Zagardo, Ross C. Gruber, Juwen C. DuBois, 2018, Pharmacology & therapeutics.

Loss of Gas6 and Axl signaling results in extensive axonal damage, motor deficits, prolonged neuroinflammation, and less remyelination following cuprizone exposure

C. Raine, B. Shafit-Zagardo, A. Ray, 2017, Glia.

Expression of monocyte/macrophage growth factors and receptors in the central nervous system.

C. Brosnan, J. Berman, B. Shafit-Zagardo, 1993, Advances in neurology.

Inhibition of human neuroblastoma cell growth by CAY10404, a highly selective Cox-2 inhibitor

B. Vikram, J. Butler, B. Shafit-Zagardo, 2004, Journal of Neuro-Oncology.

Localization and characterization of the binding site for the regulatory subunit of type II cAMP-dependent protein kinase on MAP2

J. Erlichman, B. Shafit-Zagardo, M. Dammerman, 1989, Neuron.

KpnI families of long, interspersed repetitive DNAs in human and other primate genomes.

J. Maio, B. Shafit-Zagardo, F. L. Brown, 1982, Nucleic acids research.

Up‐regulation of MAP2e‐expressing oligodendrocytes in the white matter of patients with HIV‐1 encephalitis

Sunhee C. Lee, B. Shafit-Zagardo, Meng‐Liang Zhao, 2002, Neuropathology and applied neurobiology.

Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis

B. Shafit-Zagardo, A. Ray, Peter Davies, 2020, Journal of Neuroinflammation.

Autophagy Is a Tolerance-Avoidance Mechanism that Modulates TCR-Mediated Signaling and Cell Metabolism to Prevent Induction of T Cell Anergy

P. Coffer, F. Macian, S. Vastert, 2018, Cell reports.

GAS6 Enhances Repair Following Cuprizone-Induced Demyelination

Xiaosong Li, G. Schwartz, C. Raine, 2010, PloS one.

In brain, Axl recruits Grb2 and the p85 regulatory subunit of PI3 kinase; in vitro mutagenesis defines the requisite binding sites for downstream Akt activation

J. Backer, B. Varnum, Ying Yan, 2008, Journal of neurochemistry.

Okadaic Acid Induces Early Changes in Microtubule‐Associated Protein 2 and γ Phosphorylation Prior to Neurodegeneration in Cultured Cortical Neurons

C. Arias, P. Davies, B. Shafit-Zagardo, 1993, Journal of neurochemistry.

Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis

C. Brosnan, F. Macian, B. Shafit-Zagardo, 2011, Journal of Neuroinflammation.

Differential expression of exons 10 and 11 in normal tau and tau associated with paired helical filaments

S. Yen, B. Shafit-Zagardo, H. Ksiȩżak-Reding, 1995, Journal of neuroscience research.

Axl−/− mice have delayed recovery and prolonged axonal damage following cuprizone toxicity

C. Brosnan, B. Shafit-Zagardo, Y. Kress, 2008, Brain Research.

Mice Devoid of Tau Have Increased Susceptibility to Neuronal Damage in Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis

C. Brosnan, P. Davies, B. Shafit-Zagardo, 2012, Journal of neuropathology and experimental neurology.

Defective myelination in an RNA polymerase III mutant leukodystrophic mouse

C. Branch, I. Willis, R. Moir, 2020, Proceedings of the National Academy of Sciences.

Regional localization of the regulatory subunit (RIIβ) of the type II cAMP-dependent protein kinase in human brain

D. Dickson, P. Davies, J. Erlichman, 1992, Brain Research.

CSF-1 expression is upregulated in astrocyte cultures by IL-1 and TNF and affects microglial proliferation and morphology in organotypic cultures

C. Brosnan, B. Shafit-Zagardo, M. Bornstein, 1993, International Journal of Developmental Neuroscience.

Inhibition of human Neuroblastoma in SCID mice by low-dose of selective Cox-2 inhibitor Nimesulide

B. Shafit-Zagardo, B. Parashar, 2006, Journal of Neuro-Oncology.

TMEM106B Puncta Is Increased in Multiple Sclerosis Plaques, and Reduced Protein in Mice Results in Delayed Lipid Clearance Following CNS Injury

S. Strittmatter, J. Goldman, B. Shafit-Zagardo, 2023, Cells.

Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis

C. Brosnan, F. Macian, B. Shafit-Zagardo, 2011, Journal of Neuroinflammation.

Survivin inhibition induces human neural tumor cell death through caspase‐independent and ‐dependent pathways

S. Agrawal, S. Mani, B. Shafit-Zagardo, 2001, Journal of neurochemistry.

Sequence of a human MAP‐2 region sharing epitopes with Alzheimer neurofibrillary tangles

S. Yen, B. Shafit-Zagardo, M. Dammerman, 1989, Journal of neuroscience research.

Three Unique 5′ Untranslated Regions Are Spliced to Common Coding Exons of High‐ and Low‐Molecular‐Weight Microtubule‐Associated Protein‐2

B. Shafit-Zagardo, N. Kalcheva, 1995, Journal of neurochemistry.