R. Conradi

发表

Physicochemical determinants of passive membrane permeability: role of solute hydrogen-bonding potential and volume.

J. Goodwin, R. Conradi, N. Ho, 2001, Journal of medicinal chemistry.

Letters to the Editor

R. Guy, R. Potts, R. Conradi, 2004, Pharmaceutical Research.

Epithelial cell permeability of a series of peptidic HIV protease inhibitors: aminoterminal substituent effects.

R. Conradi, P. S. Burton, Allen R. Hilgers, 1994, Journal of drug targeting.

Smoothened antagonists for hair inhibition.

Danielle E. Dettling, V. Shanmugasundaram, M. Swaroop, 2010, Bioorganic & medicinal chemistry letters.

Peptidomimetic Inhibitors of Human Immunodeficiency Virus Protease ( HIV‐PR): Design, Enzyme Binding and Selectivity, Antiviral Efficacy, and Cell Permeability Properties.

D. Decamp, C. Craik, W. Lowther, 1995 .

Prostaglandin prodrugs VI: structure-thermodynamic activity and structure-aqueous solubility relationships.

B. D. Anderson, R. Conradi, 1980, Journal of pharmaceutical sciences.

Strategies in the design of solution-stable, water-soluble prodrugs II: properties of micellar prodrugs of methylprednisolone.

B. D. Anderson, R. Conradi, S. Nail, 1985, Journal of pharmaceutical sciences.

The Influence of Peptide Structure on Transport Across Caco-2 Cells. II. Peptide Bond Modification Which Results in Improved Permeability

R. Conradi, N. Ho, P. S. Burton, 1992, Pharmaceutical Research.

The Influence of Peptide Structure on Transport Across Caco-2 Cells

R. Conradi, N. Ho, P. S. Burton, 1991, Pharmaceutical Research.

Piperazinyl oxazolidinone antibacterial agents containing a pyridine, diazene, or triazene heteroaromatic ring.

R. Conradi, P. S. Burton, S. J. Brickner, 1998, Journal of medicinal chemistry.

An NMR study of conformations of substituted dipeptides in dodecylphosphocholine micelles: Implications for drug transport

J. Blinn, B. Stockman, J. Goodwin, 2000, Biopolymers.

Strategies in the design of solution-stable, water-soluble prodrugs I: a physical-organic approach to pro-moiety selection for 21-esters of corticosteroids.

B. D. Anderson, R. Conradi, K. Knuth, 1985, Journal of pharmaceutical sciences.

Predictive relationships in the water solubility of salts of a nonsteroidal anti-inflammatory drug.

B. D. Anderson, R. Conradi, B D Anderson, 1985, Journal of pharmaceutical sciences.

Strategies in the design of solution-stable, water-soluble prodrugs III: influence of the pro-moiety on the bioconversion of 21-esters of corticosteroids.

B. D. Anderson, R. Conradi, C. Spilman, 1985, Journal of pharmaceutical sciences.

Carboxyl group catalysis of acyl transfer reactions in corticosteroid 17- and 21-monoesters.

B. D. Anderson, R. Conradi, W. J. Lambert, 1984, Journal of pharmaceutical sciences.

Caco-2 Cell Monolayers as a Model for Drug Transport Across the Intestinal Mucosa

R. Conradi, P. S. Burton, Philip S. Burton, 1990, Pharmaceutical Research.

Influence of premicellar and micellar association on the reactivity of methylprednisolone 21-hemiesters in aqueous solution.

B. D. Anderson, R. Conradi, K. Johnson, 1983, Journal of pharmaceutical sciences.

In vitro permeability of peptidomimetic drugs : the role of polarized efflux pathways as additional barriers to absorption

J. Goodwin, R. Conradi, N. Ho, 1997 .

Lack of accumulation of midazolam in plasma and lipoprotein fractions during intravenous lipid infusions in patients on artificial respiration

M. Kohlmeier, I. Walter‐Sack, B. Kohl, 2004, European Journal of Clinical Pharmacology.

Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.

V. Shanmugasundaram, R. Conradi, Pil H. Lee, 2010, Bioorganic & medicinal chemistry letters.

Physico‐Chemical and Biological Factors that Influence a Drug's Cellular Permeability by Passive Diffusion

R. Borchardt, R. Conradi, P. S. Burton, 2008 .

How structural features influence the biomembrane permeability of peptides.

R. Borchardt, R. Conradi, N. Ho, 1996, Journal of pharmaceutical sciences.

Mechanism, structure-activity studies, and potential applications of glutathione S-transferase-catalyzed cleavage of sulfonamides.

A. Tomasselli, R. Heinrikson, K. Koeplinger, 1999, Drug metabolism and disposition: the biological fate of chemicals.

Evidence for a polarized efflux system for peptides in the apical membrane of Caco-2 cells.

R. Conradi, N. Ho, P. S. Burton, 1993, Biochemical and biophysical research communications.

B) Mechanisms of peptide and protein absorption

R. Conradi, P. S. Burton, Allen R. Hilgers, 1991 .

In Vitro/in Vivo Models for Peptide Oral Absorption: Comparison of Caco-2 Cell Permeability with Rat Intestinal Absorption of Renin Inhibitory Peptides

R. Conradi, P. S. Burton, B. Rush, 1993, Pharmaceutical Research.

A biophysical model of passive and polarized active transport processes in Caco-2 cells: approaches to uncoupling apical and basolateral membrane events in the intact cell.

R. Conradi, N. Ho, P. S. Burton, 1995, Journal of pharmaceutical sciences.

Strategies toward predicting peptide cellular permeability from computed molecular descriptors.

T. Vidmar, J. Goodwin, R. Conradi, 1999, The journal of peptide research : official journal of the American Peptide Society.

The determination of total and unbound midazolam in human plasma. A comparison of high performance liquid chromatography, gas chromatography and gas chromatography/mass spectrometry.

I. Walter‐Sack, R. Conradi, J. Rudi, 1990, Biomedical chromatography : BMC.

The relationship between peptide structure and transport across epithelial cell monolayers

R. Conradi, N. Ho, P. S. Burton, 1992 .

Small molecule peptidomimetics containing a novel phosphotyrosine bioisostere inhibit protein tyrosine phosphatase 1B and augment insulin action.

X Y Wang, M. Swanson, D. Ogg, 2001, Biochemistry.

Peptidomimetic inhibitors of human immunodeficiency virus protease (HIV-PR): Design, enzyme binding and selectivity, antiviral efficacy, and cell permeability properties

D. Decamp, C. Craik, W. Lowther, 1993 .

A non-aqueous partitioning system for predicting the oral absorption potential of peptides

Thomas J. Vidmar, D. Paterson, T. Vidmar, 1994 .