E. Murphy

发表

Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRβ/B-RAF

I. Tsigelny, S. Anand, P. Vogt, 2010, Proceedings of the National Academy of Sciences.

A Role for VEGF as a Negative Regulator of Pericyte Function and Vessel Maturation

Jianhua Huang, Christian Stockmann, David A. Cheresh, 2008, Nature.

Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane.

M. Iruela-Arispe, T. Byzova, D. Cheresh, 2012, Blood.

A role for VEGF as a negative regulator of pericyte function and vessel maturation.

R. Johnson, D. Cheresh, E. Murphy, 2008, Nature.

EGFR-dependent pancreatic carcinoma cell metastasis via Rap1 activation

David A. Cheresh, S. Anand, D. Schlaepfer, 2011, Oncogene.

EGFR-Mediated Carcinoma Cell Metastasis Mediated by Integrin αvβ5 Depends on Activation of c-Src and Cleavage of MUC1

S. Anand, S. Lim, D. Schlaepfer, 2012, PloS one.

Formation of endothelial lumens requires a coordinated PKCϵ-, Src-, Pak- and Raf-kinase-dependent signaling cascade downstream of Cdc42 activation

Amber N. Stratman, G. Davis, D. Cheresh, 2009, Journal of Cell Science.

MicroRNA-132–mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis

S. Anand, J. Lindquist, R. Mukthavaram, 2010, Nature Medicine.

EGF816 Exerts Anticancer Effects in Non-Small Cell Lung Cancer by Irreversibly and Selectively Targeting Primary and Acquired Activating Mutations in the EGF Receptor.

J. Barretina, Jennifer L. Harris, J. Engelman, 2016, Cancer research.

Vitronectin-Binding Integrins in Cancer

D. Stupack, E. Murphy, Eric A. Murphy, 2010 .

Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis

Milan Makale, W. Wrasidlo, M. Makale, 2008, Proceedings of the National Academy of Sciences.

A MEK-independent role for CRAF in mitosis and tumor progression

S. Anand, D. Cheresh, S. Advani, 2011, Nature Medicine.

Oncogenic Ras/Src cooperativity in pancreatic neoplasia

D. Tarin, A. Lowy, D. Cheresh, 2011, Oncogene.

RBBP9: A tumor-associated serine hydrolase activity required for pancreatic neoplasia

D. Tarin, Sherry L. Niessen, B. Cravatt, 2009, Proceedings of the National Academy of Sciences.

Targeted Nanogels: A Versatile Platform for Drug Delivery to Tumors

R. Mukthavaram, D. Cheresh, E. Murphy, 2011, Molecular Cancer Therapeutics.

Abstract 1734:In vitrocharacterization of EGF816, a third-generation mutant-selective EGFR inhibitor

Jennifer L. Harris, S. Bender, N. Pathan, 2014 .

Abstract 1733: EGF816, a novel covalent inhibitor of mutant-selective epidermal growth factor receptor, overcomes T790M-mediated resistance in NSCLC

S. Bender, M. Vaillancourt, S. Kasibhatla, 2014 .