V. Dudkin

发表

Toward fully synthetic carbohydrate-based HIV antigen design: on the critical role of bivalency.

W. Olson, S. Danishefsky, V. Dudkin, 2004, Journal of the American Chemical Society.

Engineering a targeted delivery platform using Centyrins.

G. Gilliland, S. Jacobs, K. O'Neil, 2016, Protein engineering, design & selection : PEDS.

Evaluation of a Centyrin-Based Near-Infrared Probe for Fluorescence-Guided Surgery of Epidermal Growth Factor Receptor Positive Tumors.

P. Low, S. Singhal, K. O'Neil, 2017, Bioconjugate chemistry.

University of Groningen CD 1 c presentation of synthetic glycolipid antigens with foreign alkyl branching motifs

B. Feringa, D. Moody, A. Minnaard, 2017 .

CD1c presentation of synthetic glycolipid antigens with foreign alkyl branching motifs.

B. Feringa, D. Moody, A. Minnaard, 2007, Chemistry & biology.

Bioanalytical workflow for novel scaffold protein-drug conjugates: quantitation of total Centyrin protein, conjugated Centyrin and free payload for Centyrin-drug conjugate in plasma and tissue samples using liquid chromatography-tandem mass spectrometry.

K. O'Neil, S. Goldberg, Naidong Weng, 2018, Bioanalysis.

Fully synthetic carbohydrate HIV antigens designed on the logic of the 2G12 antibody.

J. Shiver, A. Finnefrock, J. Joyce, 2007, Journal of the American Chemical Society.

An oligosaccharide-based HIV-1 2G12 mimotope vaccine induces carbohydrate-specific antibodies that fail to neutralize HIV-1 virions

J. Shiver, J. Joyce, M. Chastain, 2008, Proceedings of the National Academy of Sciences.

Reducing oligosaccharides via glycal assembly: on the remarkable stability of anomeric hydroxyl groups to global deprotection with sodium in liquid ammonia

S. Danishefsky, U. Iserloh, V. Dudkin, 2002 .

In pursuit of carbohydrate-based HIV vaccines, part 1: The total synthesis of hybrid-type gp120 fragments.

S. Danishefsky, V. Dudkin, X. Geng, 2004, Angewandte Chemie.

A Strategy for Selective Deletion of Autoimmunity-Related T Cells by pMHC-Targeted Delivery

R. Getts, S. Goldberg, V. Dudkin, 2021, Pharmaceutics.

Intratracheal Administration of siRNA Triggers mRNA Silencing in the Lung to Modulate T Cell Immune Response and Lung Inflammation

J. Burchard, L. Sepp-Lorenzino, T. Cash-Mason, 2019, Molecular therapy. Nucleic acids.

Discovery of 5-aryl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones as positive allosteric modulators of metabotropic glutamate subtype-2 (mGlu2) receptors with efficacy in a preclinical model of psychosis.

Sarah L. Huszar, J. Uslaner, M. Jacobson, 2016, Bioorganic & medicinal chemistry letters.

Why are the hydroxy groups of partially protected N-acetylglucosamine derivatives such poor glycosyl acceptors, and what can be done about it? A comparative study of the reactivity of N-acetyl-, N-phthalimido-, and 2-azido-2-deoxy-glucosamine derivatives in glycosylation. 2-Picolinyl ethers as react

V. Dudkin, D. Crich, 2001, Journal of the American Chemical Society.

Optimization of a pyrazoloquinolinone class of Chk1 kinase inhibitors.

Lawrence C Kuo, Laura Sepp-Lorenzino, Weikang Tao, 2007, Bioorganic & medicinal chemistry letters.

Confirmation of the connectivity of 4,8,12,16,20-pentamethylpentacosylphoshoryl beta-D-mannopyranoside, an unusual beta-mannosyl phosphoisoprenoid from Mycobacterium avium, through synthesis.

V. Dudkin, D. Crich, 2002, Journal of the American Chemical Society.

A concise route to the core pentasaccharide of N-linked glycoproteins

S. Danishefsky, V. Dudkin, Justin S. Miller, 2003 .

A short synthesis of the trisaccharide building block of the N-linked glycans

V. Dudkin, D. Crich, 2003 .

A Nanoparticle Platform for Accelerated In Vivo Oral Delivery Screening of Nucleic Acids

Margaret M. Billingsley, R. Zhang, M. J. Mitchell, 2020 .

A highly convergent synthesis of an N-linked glycopeptide presenting the H-type 2 human blood group determinant

P. Seeberger, S. Danishefsky, U. Iserloh, 2006 .

Chemical synthesis of normal and transformed PSA glycopeptides.

S. Danishefsky, V. Dudkin, Justin S. Miller, 2004, Journal of the American Chemical Society.

An unusual example of steric buttressing in glycosylation

V. Dudkin, D. Crich, 2000 .

In pursuit of carbohydrate-based HIV vaccines, part 2: The total synthesis of high-mannose-type gp120 fragments--evaluation of strategies directed to maximal convergence.

S. Danishefsky, V. Dudkin, X. Geng, 2004, Angewandte Chemie.

Efficient, diastereoselective chemical synthesis of a beta-mannopyranosyl phosphoisoprenoid.

V. Dudkin, D. Crich, 2000, Organic letters.

Toward fully synthetic N-linked glycoproteins.

T. Muir, G. Lyon, S. Danishefsky, 2003, Angewandte Chemie.

Toward a Prostate Specific Antigen-Based Prostate Cancer Diagnostic Assay: Preparation of Keyhole Limpet Hemocyanin -Conjugated Normal and Transformed Prostate Specific Antigen Fragments

D. Scheinberg, C. Antczak, S. Danishefsky, 2008, Journal of the American Chemical Society.

Small Molecule Mimetics of an HIV-1 gp41 Fusion Intermediate as Vaccine Leads

G. McGaughey, E. Ottinger, M. Citron, 2010, The Journal of Biological Chemistry.

Pyridyl aminothiazoles as potent inhibitors of Chk1 with slow dissociation rates.

Laura Sepp-Lorenzino, S. Stirdivant, M. Ikuta, 2012, Bioorganic & medicinal chemistry letters.

Pyridyl aminothiazoles as potent Chk1 inhibitors: optimization of cellular activity.

S. Stirdivant, Weikang Tao, L. Sepp-Lorenzino, 2012, Bioorganic & medicinal chemistry letters.

Centyrin ligands for extrahepatic delivery of siRNA

M. Manoharan, K. O'Neil, L. Sepp-Lorenzino, 2021, Molecular therapy : the journal of the American Society of Gene Therapy.