J. Lloyd

发表

Estimation of hERG inhibition of drug candidates using multivariate property and pharmacophore SAR.

Stephen R. Johnson, A. Doweyko, H. Yue, 2007, Bioorganic & medicinal chemistry.

Biphenylsulfonamide endothelin antagonists: structure-activity relationships of a series of mono- and disubstituted analogues and pharmacology of the orally active endothelin antagonist 2'-amino-N- (3,4-dimethyl-5-isoxazolyl)-4'-(2-methylpropyl)[1, 1'-biphenyl]-2-sulfonamide (BMS-187308).

S. Spergel, N. Murugesan, Z. Gu, 1998, Journal of medicinal chemistry.

N-[1-Aryl-2-(1-imidazolo)ethyl]-guanidine derivatives as potent inhibitors of the bovine mitochondrial F1F0 ATP hydrolase.

K. J. Yost, Hsinglin Lan, L. Hamann, 2004, Bioorganic & medicinal chemistry letters.

Identification of Reversible Small Molecule Inhibitors of Endothelial Lipase (EL) which Demonstrate HDL-C Increase In Vivo.

David S. Taylor, K. Behnia, E. Liu, 2020, Journal of medicinal chemistry.

Design and synthesis of 4-substituted benzamides as potent, selective, and orally bioavailable I(Ks) blockers.

A. Mathur, P. Stein, M. Conder, 2001, Journal of Medicinal Chemistry.

Design and synthesis of 4-substituted benzamides as potent, selective, and orally bioavailable IKs blockers

A. Mathur, P. Stein, Mark A. Smith, 2001 .

Discovery of 5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)quinazolin-4-amine as a Potent I Kur Inhibitor.

S. Mandlekar, Abhisek Banerjee, M. Conder, 2016, ACS medicinal chemistry letters.

Tetrahydronaphthalene-derived amino alcohols and amino ketones as potent and selective inhibitors of the delayed rectifier potassium current IKs.

John Lloyd, Saleem Ahmad, P. Stein, 2004, Bioorganic & medicinal chemistry letters.

Pyrrolidine amides of pyrazolodihydropyrimidines as potent and selective KV1.5 blockers.

Huabin Sun, Christine S. Huang, M. Conder, 2010, Bioorganic & medicinal chemistry letters.

Benzopyran sulfonamides as KV1.5 potassium channel blockers.

T. Huynh, Wayne Vaccaro, M. Conder, 2007, Bioorganic & medicinal chemistry letters.

Conformationally constrained ortho-anilino diaryl ureas: discovery of 1-(2-(1'-neopentylspiro[indoline-3,4'-piperidine]-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea, a potent, selective, and bioavailable P2Y1 antagonist.

Steven A. Spronk, P. Lam, D. Schnur, 2013, Journal of medicinal chemistry.

2-Aminothiazole based P2Y(1) antagonists as novel antiplatelet agents.

P. Lam, R. Rehfuss, Christine S. Huang, 2013, Bioorganic & medicinal chemistry letters.

Dihydropyrazolopyrimidine inhibitors of K(V)1.5 (I(Kur)).

T. Huynh, Wayne Vaccaro, M. Conder, 2008, Bioorganic & medicinal chemistry letters.

Dihydropyrazolopyrimidines containing benzimidazoles as K(V)1.5 potassium channel antagonists.

Huabin Sun, T. Huynh, Wayne Vaccaro, 2009, Bioorganic & medicinal chemistry letters.

Solid phase synthesis of phosphinic acid endothelin converting enzyme inhibitors

J. Barrish, J. Hunt, A. Tymiak, 1996 .

Design, synthesis and evaluation of phenethylaminoheterocycles as K(v)1.5 inhibitors.

Huabin Sun, M. Conder, J. Lloyd, 2014, Bioorganic & medicinal chemistry letters.

Quinoline-4-carboxylic acids as angiotensin II receptor antagonists

T. Waldron, S. Moreland, K. Dickinson, 1994 .

Selective IKur Inhibitors for the Potential Treatment of Atrial Fibrillation: Optimization of the Phenyl Quinazoline Series Leading to Clinical Candidate 5-[5-Phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]pyridine-3-sulfonamide.

S. Mandlekar, A. Mathur, Abhisek Banerjee, 2017, Journal of medicinal chemistry.

Triazolo and imidazo dihydropyrazolopyrimidine potassium channel antagonists.

M. Blanar, M. Conder, J. Lloyd, 2013, Bioorganic & medicinal chemistry letters.

Pyrano-[2,3b]-pyridines as potassium channel antagonists.

M. Conder, J. Lloyd, P. Levesque, 2008, Bioorganic & medicinal chemistry letters.

Design, synthesis and evaluation of phenethylaminoheterocycles as K(v)1.5 inhibitors.

Huabin Sun, M. Conder, J. Lloyd, 2014, Bioorganic & medicinal chemistry letters.

Triazolo and imidazo dihydropyrazolopyrimidine potassium channel antagonists.

M. Blanar, M. Conder, J. Lloyd, 2013, Bioorganic & medicinal chemistry letters.