J. Henquin

发表

Regulation of insulin secretion: a matter of phase control and amplitude modulation

J. Henquin, 2009, Diabetologia.

Concentration Dependence and Time Course of the Effects of Glucose on Adenine and Guanine Nucleotides in Mouse Pancreatic Islets*

G. Van den Berghe, J. Henquin, P. Detimary, 1996, The Journal of Biological Chemistry.

Pulsatility of insulin and glucagon release: physiological significance and pharmacological implications

G. Paolisso, A. Scheen, J. Henquin, 1987, Diabetologia.

Stable and diffusible pools of nucleotides in pancreatic islet cells.

J. Henquin, J. Jonas, P. Detimary, 1996, Endocrinology.

High incidence of hypoglycaemia in African patients treated with intravenous quinine for severe malaria.

J. Henquin, C. Delacollette, W. Okitolonda, 1987, British medical journal.

Do Pancreatic β Cells “Taste” Nutrients to Secrete Insulin?

J. Henquin, 2012, Science Signaling.

Antioxidants N-acetyl-L-cysteine and manganese(III)tetrakis (4-benzoic acid)porphyrin do not prevent beta-cell dysfunction in rat islets cultured in high glucose for 1 wk.

Y. Guiot, J. Henquin, J. Jonas, 2006, American journal of physiology. Endocrinology and metabolism.

Cyclic variations of glucose-induced electrical activity in pancreatic B cells

H. Meissner, J. Henquin, W. Schmeer, 1982, Pflügers Archiv.

Effects of a calcium channel agonist on the electrical, ionic and secretory events in mouse pancreatic B-cells.

H. Meissner, J. Henquin, W. Schmeer, 1985, Biochemical and biophysical research communications.

Congenital Hyperinsulinism Caused by Hexokinase I Expression or Glucokinase-Activating Mutation in a Subset of β-Cells

C. Sempoux, Y. Guiot, J. Henquin, 2013, Diabetes.

cAMP-mediated and metabolic amplification of insulin secretion are distinct pathways sharing independence of β-cell microfilaments.

J. Henquin, M. Nenquin, N. Mourad, 2012, Endocrinology.

Metabolic amplification of insulin secretion by glucose is independent of β-cell microtubules.

J. Henquin, M. Nenquin, N. Mourad, 2011, American journal of physiology. Cell physiology.

Metabolic amplifying pathway increases both phases of insulin secretion independently of beta-cell actin microfilaments.

J. Henquin, M. Nenquin, N. Mourad, 2010, American journal of physiology. Cell physiology.

Glucose and Pharmacological Modulators of ATP-Sensitive K+ Channels Control [Ca2+]c by Different Mechanisms in Isolated Mouse α-Cells

P. Gilon, Y. Guiot, J. Henquin, 2009, Diabetes.

Sulphonylureas do not increase insulin secretion by a mechanism other than a rise in cytoplasmic Ca2+ in pancreatic B-cells.

P. Gilon, J. Henquin, M. García-Barrado, 1996, European journal of pharmacology.

G protein‐dependent inhibition of L‐type Ca2+ currents by acetylcholine in mouse pancreatic B‐cells.

P. Rorsman, J. Gromada, J. Yakel, 1997, The Journal of physiology.

Tolbutamide and diazoxide influence insulin secretion by changing the concentration but not the action of cytoplasmic Ca2+ in beta-cells.

P. Gilon, J. Henquin, M. Nenquin, 1998, Diabetes.

Intestinal absorption of sorbitol and effects of its acute administration on glucose homeostasis in normal rats

A. Lauwers, J. Henquin, C. Daumerie, 1985, British Journal of Nutrition.

Inhibition of protein synthesis sequentially impairs distinct steps of stimulus-secretion coupling in pancreatic beta cells.

M. Ravier, P. Gilon, J. Henquin, 2001, Endocrinology.

Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells.

P. Gilon, J. Henquin, P. Detimary, 1993, The Journal of clinical investigation.

Galanin and epinephrine act on distinct receptors to inhibit insulin release by the same mechanisms including an increase in K+ permeability of the B-cell membrane.

G. Drews, J. Henquin, M. Nenquin, 1990, Endocrinology.

ATP-sensitive K+ channels may control glucose-induced electrical activity in pancreatic B-cells.

J. Henquin, 1988, Biochemical and biophysical research communications.

Phlorizin treatment of diabetic rats partially reverses the abnormal expression of genes involved in hepatic glucose metabolism

S. Brichard, J. Girard, J. Henquin, 1993, Diabetologia.

Mechanisms of the Stimulation of Insulin Release by Saturated Fatty Acids: A Study of Palmitate Effects in Mouse β-cells

P. Gilon, J. Henquin, M. Nenquin, 1994, Diabetes.

Repercussions of chronic protein-calorie malnutrition on glucose homeostasis in the rat

S. Brichard, J. Henquin, W. Okitolonda, 1987, Diabetologia.

Improvement of mild hypoinsulinaemic diabetes in the rat by low non-toxic doses of vanadate.

J. Henquin, F. Cartón, L. Ongemba, 1994, The Journal of endocrinology.

Calcium signaling and secretory granule pool dynamics underlie biphasic insulin secretion and its amplification by glucose: experiments and modeling.

M. G. Pedersen, J. Henquin, A. Tagliavini, 2019, American journal of physiology. Endocrinology and metabolism.

Signals and pools underlying biphasic insulin secretion.

M. Ravier, J. Henquin, J. Jonas, 2002, Diabetes.

Hierarchy of the β‐cell signals controlling insulin secretion

M. Ravier, P. Gilon, J. Henquin, 2003, European journal of clinical investigation.

Increased glucose sensitivity of both triggering and amplifying pathways of insulin secretion in rat islets cultured for 1 wk in high glucose.

P. Gilon, Y. Guiot, J. Henquin, 2004, American journal of physiology. Endocrinology and metabolism.

Quinine‐induced modifications of insulin release and glucose metabolism by isolated pancreatic islets

J. Henquin, B. Horemans, M. Nenquin, 1975, FEBS letters.

Shortcomings of current models of glucose‐induced insulin secretion

M. Ravier, J. Henquin, M. Nenquin, 2009, Diabetes, obesity & metabolism.

Pathways in beta-cell stimulus-secretion coupling as targets for therapeutic insulin secretagogues.

J. Henquin, 2004, Diabetes.

Overnight Culture Unmasks Glucose-induced Insulin Secretion in Mouse Islets Lacking ATP-sensitive K+ Channels by Improving the Triggering Ca2+ Signal*

J. Henquin, M. Nenquin, A. Szollosi, 2007, Journal of Biological Chemistry.

Glucose Stimulates Ca2+ Influx and Insulin Secretion in 2-Week-old β-Cells Lacking ATP-sensitive K+ Channels*

J. Bryan, L. Aguilar-Bryan, J. Henquin, 2007, Journal of Biological Chemistry.

G Protein-independent Activation of an Inward Na+Current by Muscarinic Receptors in Mouse Pancreatic β-Cells*

P. Gilon, J. Henquin, J. Rolland, 2002, The Journal of Biological Chemistry.

Tenth Annual Meeting of the European Association for the Study of Diabetes

A. J. Honour, W. A. Müller, P. Blackshear, 1974, Diabetologia.

Glucose Regulation of Insulin Secretion Independent of the Opening or Closure of Adenosine Triphosphate-Sensitive K+ Channels in β Cells.

J. Henquin, Yoshihiko Sato, M. Anello, 1999, Endocrinology.

Mechanisms of the stimulation of insulin release by oxytocin in normal mouse islets.

G. Drews, J. Henquin, Z. Gao, 1991, The Biochemical journal.

Adamantane derivatives: a new class of insulin secretagogues

J. Henquin, M. Garrino, M.G. Garrino, 1987, British journal of pharmacology.

The challenge of correctly reporting hormones content and secretion in isolated human islets

J. Henquin, 2019, Molecular metabolism.

Improvement of glucose homeostasis and hepatic insulin resistance in ob/ob mice given oral molybdate.

S. Brichard, C. Bailey, J. Henquin, 1997, The Journal of endocrinology.

Influence of glucagon on natriuresis and glucose‐induced sodium retention in the fasting obese subject *

J. Henquin, J. Crabbé, J. Kolanowski, 1977, European journal of clinical investigation.

Section 4: Oscillations in -Cells Control Mechanisms of the Oscillations of Insulin Secretion In Vitro and In Vivo

M. Ravier, P. Gilon, J. Henquin, 2002 .

Dynamics of glucose-induced insulin secretion in normal human islets.

J. Kerr-Conte, D. Dufrane, J. Henquin, 2015, American journal of physiology. Endocrinology and metabolism.

Cationic Environment and Dynamics of Insulin Secretion: II. Effect of a High Concentration of Potassium

J. Henquin, A. Lambert, 1974, Diabetes.

Pancreatic alpha cell mass in European subjects with type 2 diabetes

J. Henquin, J. Rahier, 2011, Diabetologia.

Tolbutamide stimulation and inhibition of insulin release: Studies of the underlying ionic mechanisms in isolated rat islets

J. Henquin, 1980, Diabetologia.

Influence of low- and high-protein diets on glucose homeostasis in the rat

S. Brichard, J. Henquin, W. Okitolonda, 1988, British Journal of Nutrition.

isletsinduced by arginine and tolbutamide in mouse Dual mechanism of the potentiation by glucose of insulin

M. Ravier, J. Henquin, N. Ishiyama, 2016 .

Dual mechanism of the potentiation by glucose of insulin secretion induced by arginine and tolbutamide in mouse islets.

M. Ravier, J. Henquin, N. Ishiyama, 2006, American journal of physiology. Endocrinology and metabolism.

SERCA3 ablation does not impair insulin secretion but suggests distinct roles of different sarcoendoplasmic reticulum Ca(2+) pumps for Ca(2+) homeostasis in pancreatic beta-cells.

A. Arredouani, P. Gilon, F. Wuytack, 2002, Diabetes.

Effect of creatine supplementation on creatine and glycogen content in rat skeletal muscle.

P. Hespel, E. Richter, B. Kiens, 2001, Acta physiologica Scandinavica.

Modulation of the effect of acetylcholine on insulin release by the membrane potential of B cells.

M. Hermans, J. Henquin, W. Schmeer, 1987, Endocrinology.

Unbound rather than total concentration and saturation rather than unsaturation determine the potency of fatty acids on insulin secretion

J. Henquin, M. Nenquin, C. Warnotte, 1999, Molecular and Cellular Endocrinology.

Oral selenate improves glucose homeostasis and partly reverses abnormal expression of liver glycolytic and gluconeogenic enzymes in diabetic rats

S. Brichard, J. Buchet, J. Henquin, 2004, Diabetologia.

In Vivo and In Vitro Glucose-Induced Biphasic Insulin Secretion in the Mouse Pattern and Role of Cytoplasmic Ca 2 and Amplification Signals in-Cells

B. Ahrén, J. Henquin, M. Nenquin, 2006 .

Long in the shade, glucagon re‐occupies centre court

D. Accili, S. Seino, C. Boitard, 2011, Diabetes, obesity & metabolism.

Effects of glibenclamide on pancreatic β-cell proliferation in vivo

Y. Guiot, J. Henquin, J. Rahier, 1994 .

Glucose-induced cytosolic pH changes in beta-cells and insulin secretion are not causally related: studies in islets lacking the Na+/H+ exchangeR NHE1.

P. Moulin, J. Henquin, J. Jonas, 2007, The Journal of biological chemistry.

Increased glucose sensitivity of stimulus-secretion coupling in islets from Psammomys obesus after diet induction of diabetes.

E. Cerasi, N. Kaiser, J. Henquin, 2002, Diabetes.

Potential role of the early response gene c-myc in beta-cell adaptation to changes in glucose concentration.

G. Steil, G. Weir, J. Henquin, 2001, Diabetes.

Glucose modulation of spike activity independently from changes in slow waves of membrane potential in mouse B-cells

M. Bozem, J. Henquin, 1988, Pflügers Archiv.

Forskolin suppresses the slow cyclic variations of glucose-induced electrical activity in pancreatic B cells.

H. Meissner, J. Henquin, W. Schmeer, 1984, Biochemical and biophysical research communications.

D-Glucose inhibits potassium efflux from pancreatic islet cells

J. Henquin, 1978, Nature.

The K+-ATP channel-independent pathway of regulation of insulin secretion by glucose: in search of the underlying mechanism.

J. Henquin, Y. Sato, 1998, Diabetes.

Morphological and functional characteristics of islets neoformed during tissue culture of fetal rat pancreas

J. Henquin, J. Mourmeaux, C. Remade, 1985, Molecular and Cellular Endocrinology.

A Minimum of Fuel Is Necessary for Tolbutamide to Mimic the Effects of Glucose on Electrical Activity in Pancreatic β-Cells.

J. Henquin, 1998, Endocrinology.

Signal transduction: regulation of insulin secretion by changes in Ca2+ concentration and action in pancreatic B-cells

P. Gilon, P. Timary, J. Henquin, 1999 .

Phentolamine and yohimbine inhibit ATP‐sensitive K+ channels in mouse pancreatic β‐cells

J. Henquin, T. Plant, 1990, British journal of pharmacology.

Effects of stimulation of adenylate cyclase and protein kinase-C on cultured fetal rat B-cells.

C. Remacle, J. Henquin, J. Mourmeaux, 1989, Endocrinology.

Do oscillations of insulin secretion occur in the absence of cytoplasmic Ca2+ oscillations in beta-cells?

M. Ravier, J. Henquin, J. Jonas, 2002, Diabetes.

Mechanism of the stimulation of insulin release in vitro by HB 699, a benzoic acid derivative similar to the non-sulphonylurea moiety of glibenclamide

H. Meissner, J. Henquin, M. Garrino, 1985, Diabetologia.

The fiftieth anniversary of hypoglycaemic sulphonamides. How did the mother compound work?

J. Henquin, 1992, Diabetologia.

Multiple effects and stimulation of insulin secretion by the tyrosine kinase inhibitor genistein in normal mouse islets

P. Gilon, J. Henquin, J. Jonas, 1995, British journal of pharmacology.

Distinct effects of glucose on the synchronous oscillations of insulin release and cytoplasmic Ca2+ concentration measured simultaneously in single mouse islets.

P. Gilon, J. Henquin, 1995, Endocrinology.

Interplay between cytoplasmic Ca2+ and the ATP/ADP ratio: a feedback control mechanism in mouse pancreatic islets.

P. Gilon, J. Henquin, P. Detimary, 1998, The Biochemical journal.

The Elevation of Glutamate Content and the Amplification of Insulin Secretion in Glucose-stimulated Pancreatic Islets Are Not Causally Related*

M. Ravier, G. Bertrand, J. Henquin, 2002, The Journal of Biological Chemistry.

The Changes in Adenine Nucleotides Measured in Glucose-stimulated Rodent Islets Occur in β Cells but Not in α Cells and Are Also Observed in Human Islets*

D. Pipeleers, F. Schuit, Z. Ling, 1998, The Journal of Biological Chemistry.

Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse islets.

P. Gilon, J. Henquin, C. Lambillotte, 1997, The Journal of clinical investigation.

Magnesium uptake by pancreatic islet cells is modulated by stimulators and inhibitors of the B-cell function.

J. Henquin, M. Cogneau, M. Nenquin, 1986, European journal of biochemistry.

Glucagon immunoassay using polyethylene glycol to precipitate antibody-bound hormone

J. Henquin, P. Malvaux, A. Lambert, 1974, Diabetologia.

Diet‐ and diabetes‐induced changes of ob gene expression in rat adipose tissue

S. Brichard, J. Henquin, V. Brichard, 1995, FEBS letters.

The influence of gamma-aminobutyric acid on hormone release by the mouse and rat endocrine pancreas.

C. Remacle, G. Bertrand, P. Gilon, 1991, Endocrinology.

Relative contribution of Ca2+‐dependent and Ca2+‐independent mechanisms to the regulation of insulin secretion by glucose

J. Henquin, Yoshihiko Sato, M. Nenquin, 1998, FEBS letters.

Membrane and intracellular effects of adenosine in mouse pancreatic beta-cells.

G. Bertrand, M. Bozem, J. Henquin, 1989, The American journal of physiology.

Both Triggering and Amplifying Pathways Contribute to Fuel-induced Insulin Secretion in the Absence of Sulfonylurea Receptor-1 in Pancreatic β-Cells*

J. Bryan, L. Aguilar-Bryan, J. Henquin, 2004, Journal of Biological Chemistry.

Glucose controls cytosolic Ca2+ and insulin secretion in mouse islets lacking adenosine triphosphate-sensitive K+ channels owing to a knockout of the pore-forming subunit Kir6.2.

M. Ravier, S. Seino, T. Miki, 2009, Endocrinology.

Glucose homeostasis in magnesium-deficient rats.

J. Henquin, W. Okitolonda, A. Pottier, 1987, Metabolism: clinical and experimental.

Cell populations in the endocrine pancreas of human neonates and infants

J. Henquin, J. Rahier, J. Wallon, 1981, Diabetologia.

In vitro insulin secretion by pancreatic tissue from infants with diazoxide-resistant congenital hyperinsulinism deviates from model predictions.

C. Sempoux, C. Bellanné-Chantelot, P. de Lonlay, 2011, The Journal of clinical investigation.

Abundance of somatostatin cells in the human neonatal pancreas

J. Henquin, J. Rahier, J. Wallon, 1980, Diabetologia.

The effects of cesium chloride on insulin release, ionic fluxes and membrane potential in pancreatic B-cells.

G. Paolisso, H. Meissner, J. Henquin, 1985, Biochimica et biophysica acta.

Sparteine increases insulin release by decreasing the K+ permeability of the B-cell membrane.

G. Paolisso, H. Meissner, J. Henquin, 1985, Biochemical pharmacology.

Opposite effects of tolbutamide and diazoxide on 86Rb+ fluxes and membrane potential in pancreatic B cells.

H. Meissner, J. Henquin, 1982, Biochemical pharmacology.

Paracrine and autocrine control of insulin secretion in human islets: evidence and pending questions.

J. Henquin, 2020, American journal of physiology. Endocrinology and metabolism.

In vitro stimulation of insulin release by SL 84.0418, a new alpha 2-adrenoceptor antagonist.

J. Henquin, J. Jonas, T. Plant, 1994, European journal of pharmacology.

Morphological localisation of sulfonylurea receptor 1 in endocrine cells of human, mouse and rat pancreas

C. Sempoux, Y. Guiot, J. Henquin, 2007, Diabetologia.

Muscarinic stimulation exerts both stimulatory and inhibitory effects on the concentration of cytoplasmic Ca2+ in the electrically excitable pancreatic B-cell.

P. Gilon, J. Henquin, M. Nenquin, 1995, The Biochemical journal.

Possible links between glucose-induced changes in the energy state of pancreatic B cells and insulin release. Unmasking by decreasing a stable pool of adenine nucleotides in mouse islets.

J. Henquin, J. Jonas, P. Detimary, 1995, The Journal of clinical investigation.

The interplay between cyclic AMP and ions in the stimulus-secretion coupling in pancreatic B-cells.

J. Henquin, 1985, Archives internationales de physiologie et de biochimie.

[Ca]c response in mouse pancreatic islets

A. Arredouani, P. Gilon, J. Henquin, 2001 .

Glucose Acutely Decreases pH of Secretory Granules in Mouse Pancreatic Islets

P. Gilon, Y. Guiot, J. Henquin, 2006, Journal of Biological Chemistry.

Distinct effects of various amino acids on 45Ca2+ fluxes in rat pancreatic islets.

J. Henquin, S. Charles, Jean-Claude HENQUINt, 1983, The Biochemical journal.

Ketoisocaproic acid and leucine increase cytoplasmic pH in mouse pancreatic B cells: role of cytoplasmic Ca2+ and pH-regulating exchangers.

P. Gilon, J. Henquin, R. Shepherd, 1996, Endocrinology.

The Role of Metabolism, Cytoplasmic Ca2+, and pH-regulating Exchangers in Glucose-induced Rise of Cytoplasmic pH in Normal Mouse Pancreatic Islets (*)

R. M. Shepherd, J. Henquin, R. Shepherd, 1995, The Journal of Biological Chemistry.

Insulin secretion in islets from mice with a double knockout for the dense core vesicle proteins islet antigen-2 (IA-2) and IA-2beta.

A. Kubosaki, A. Notkins, J. Henquin, 2008, The Journal of endocrinology.

Developmental defects and rescue from glucose intolerance of a catalytically-inactive novel Ship2 mutant mouse.

S. Schiffmann, S. Schurmans, B. Vanhaesebroeck, 2012, Cellular signalling.

The permissive effect of glucose, tolbutamide and high K+ on arginine stimulation of insulin release in isolated mouse islets

M. Hermans, J. Henquin, W. Schmeer, 1987, Diabetologia.

Epinephrine modifications of insulin release and of 86Rb+ or 45Ca2+ fluxes in rat islets.

J. Henquin, T. Tamagawa, 1983, The American journal of physiology.

Enzyme‐Induced Modifications of Beta Cell Function

L. Orci, J. Henquin, A. Renold, 1974, European journal of clinical investigation.

Somatostatin and the intestinal transport of glucose and other nutrients in the anaesthetised rat.

J. Henquin, C. Daumerie, 1982, Gut.

Glucose- and concentration-dependence of vasopressin-induced hormone release by mouse pancreatic islets

J. Henquin, Zhi-Yong Gao, Michel Gérard, 1992, Regulatory Peptides.

The influence of sodium omission on alpha 2-adrenergic inhibition of insulin release by mouse islets.

G. Bertrand, J. Henquin, 1990, Life sciences.

Comparison of the effects of various vanadium salts on glucose homeostasis in streptozotocin-diabetic rats.

J. Henquin, L. Ongemba, D. Becker, 1994, European journal of pharmacology.

The ionic, electrical, and secretory effects of endogenous cyclic adenosine monophosphate in mouse pancreatic B cells: studies with forskolin.

H. Meissner, J. Henquin, 1984, Endocrinology.

The imidazoline SL 84.0418 shows stereoselectivity in blocking alpha 2-adrenoceptors but not ATP-sensitive K+ channels in pancreatic B-cells.

J. Henquin, J. Jonas, I. Angel, 1994, European journal of pharmacology.

Activators of PKA and Epac distinctly influence insulin secretion and cytosolic Ca2+ in female mouse islets stimulated by glucose and tolbutamide.

J. Henquin, M. Nenquin, 2014, Endocrinology.

Triggering and amplifying pathways of regulation of insulin secretion by glucose.

J. Henquin, J C Henquin, 2000, Diabetes.

Nutrient control of insulin secretion in perifused adult pig islets.

D. Dufrane, J. Henquin, M. Nenquin, 2007, Diabetes & metabolism.

Time and amplitude regulation of pulsatile insulin secretion by triggering and amplifying pathways in mouse islets

M. Ravier, J. Henquin, Magalie A Ravier, 2002, FEBS letters.

Two sites of glucose control of insulin release with distinct dependence on the energy state in pancreatic B-cells.

P. Gilon, J. Henquin, P. Detimary, 1994, The Biochemical journal.

Diazoxide and D600 Inhibition of Insulin Release: Distinct Mechanisms Explain the Specificity for Different Stimuli

J. Henquin, M. Nenquin, T. Tamagawa, 1982, Diabetes.

Effects of amino acids on membrane potential and 86Rb+ fluxes in pancreatic beta-cells.

H. Meissner, J. Henquin, 1981, The American journal of physiology.

Potassium ions and insulin release.

J. Henquin, A. Lambert, 1976, Journal de physiologie.

Cationic Environment and Dynamics of Insulin Secretion

J. Henquin, P. Malvaux, A. Lambert, 1975 .

Effects of putative activators of K+ channels in mouse pancreatic β‐cells

J. Henquin, T. Plant, M. Garrino, 1989 .

Effects of putative activators of K+ channels in mouse pancreatic beta-cells.

J. Henquin, T. Plant, M. Garrino, 1989, British journal of pharmacology.

Cyclic adenosine monophosphate differently affects the response of mouse pancreatic beta‐cells to various amino acids.

H. Meissner, J. Henquin, 1986, The Journal of physiology.

Glucose-induced electrical activity in beta-cells. Feedback control of ATP-sensitive K+ channels by Ca2+? [corrected].

J. Henquin, 1990, Diabetes.

Subplasmalemmal Ca2+ measurements in mouse pancreatic beta cells support the existence of an amplifying effect of glucose on insulin secretion

M. Ravier, A. Palmer, P. Gilon, 2010, Diabetologia.

The antioxidants N-acetyl-L-cystein and manganese(III)tetrakis (4-benzoic acid)porphyrin prevent in rat cultured

Y. Guiot, J. Henquin, J. Jonas, 2006 .

Disruption and stabilization of β‐cell actin microfilaments differently influence insulin secretion triggered by intracellular Ca2+ mobilization or store‐operated Ca2+ entry

J. Henquin, M. Nenquin, N. Mourad, 2012, FEBS letters.

Glucose-, calcium- and concentration-dependence of acetylcholine stimulation of insulin release and ionic fluxes in mouse islets.

M. Hermans, J. Henquin, M. García, 1988, The Biochemical journal.

Culture duration and conditions affect the oscillations of cytoplasmic calcium concentration induced by glucose in mouse pancreatic islets

P. Gilon, J. Henquin, J. Jonas, 1994, Diabetologia.

A Simple Method Using a Polymethylpenten Chamber for Isolation of Human Pancreatic Islets

J. Squifflet, P. Gianello, D. Dufrane, 2005, Pancreas.

A Simple Method Using a Polymethylpenten Chamber for Isolation of Human Pancreatic Islets

J. Squifflet, P. Gianello, D. Dufrane, 2004, Pancreas.

Inosine partially mimics the effects of glucose on ionic fluxes, electrical activity, and insulin release in mouse pancreatic B-cells

M. Bozem, J. Henquin, M. Garrino, 1987, Pflügers Archiv - European Journal of Physiology.

Tetraethylammonium potentiation of insulin release and inhibition of rubidium efflux in pancreatic islets.

J. Henquin, 1977, Biochemical and Biophysical Research Communications - BBRC.

Improvement of glucose and lipid metabolism in diabetic rats treated with molybdate.

S. Brichard, J. Henquin, A. Ozçelikay, 1996, The American journal of physiology.

Distinct mechanisms for two amplification systems of insulin release.

M. Bozem, J. Henquin, W. Schmeer, 1987, The Biochemical journal.

Bicarbonate modulation of glucose-9nduced biphasic insulin release by rat islets.

J. Henquin, A. Lambert, 1976, The American journal of physiology.

The effect of pH on 86Rubidium efflux from pancreatic islet cells

J. Henquin, 1981, Molecular and Cellular Endocrinology.

Pancreatic β‐cell mass in European subjects with type 2 diabetes

C. Sempoux, Y. Guiot, R. Goebbels, 2008, Diabetes, obesity & metabolism.

Insulinoma Localization by Glucagon-Like Peptide-1 Receptor Imaging After 18 Years of Hypoglycemia

M. Igoillo-Esteve, M. Cnop, F. Féry, 2015 .

Human Insulinomas Show Distinct Patterns of Insulin Secretion In Vitro

C. Sempoux, Y. Guiot, J. Henquin, 2015, Diabetes.

Tight links between adenine and guanine nucleotide pools in mouse pancreatic islets: a study with mycophenolic acid.

C. Xiao, J. Henquin, P. Detimary, 1997, The Biochemical journal.

Feedback control of the ATP-sensitive K(+) current by cytosolic Ca(2+) contributes to oscillations of the membrane potential in pancreatic beta-cells.

P. Gilon, J. Henquin, J. Rolland, 2002, Diabetes.

Insulin secretion: movement at all levels.

D. Steiner, E. Ferrannini, C. Boitard, 2002, Diabetes.

Sulphonylurea receptor‐1, sulphonylureas and amplification of insulin secretion by Epac activation in β cells

J. Henquin, M. Nenquin, 2016, Diabetes, obesity & metabolism.

Glucose modulates Mg2+fluxes in pancreatic islet cells

J. Henquin, M. Cogneau, M. Nenquin, 1983, Nature.

Specificity of divalent cation requirement for insulin release

J. Henquin, 2004, Pflügers Archiv.

Relative importance of extracellular and intracellular calcium for the two phases of glucose-stimulated insulin release: studies with theophylline.

J. Henquin, 1978, Endocrinology.

Extracellular bicarbonate ions and insulin secretion.

J. Henquin, A. Lambert, 1975, Biochimica et biophysica acta.

Response from the authors

P. Gilon, J. Henquin, J. Jonas, 1995, Diabetologia.

The non-sulfonylurea moiety of gliquidone mimics the effects of the parent molecule on pancreatic B-cells.

H. Meissner, J. Henquin, M. Garrino, 1986, European journal of pharmacology.

Muscarinic stimulation increases Na+ entry in pancreatic B-cells by a mechanism other than the emptying of intracellular Ca2+ pools.

P. Gilon, J. Henquin, Y. Miura, 1996, Biochemical and biophysical research communications.

Significance of membrane repolarization and cyclic AMP changes in mouse pancreatic B-cells for the inhibition of insulin release by galanin

G. Drews, J. Henquin, A. Debuyser, 1994, Molecular and Cellular Endocrinology.

A single mechanism for the stimulation of insulin release and 86Rb+ efflux from rat islets by cationic amino acids.

J. Henquin, T. Tamagawa, S. Charles, 1982, The Biochemical journal.

Impact of treatment on islet function in type 2 diabetes.

D. Steiner, E. Ferrannini, C. Boitard, 2004, Diabetes.

Pharmacological control of 86Rb efflux from mouse pancreatic islets.

G. Paolisso, J. Henquin, M. Garrino, 1986, Advances in experimental medicine and biology.

Nutrient insulin secretagogues decrease 45Ca2+ efflux from islet cells by a mechanism other than the inhibition of the Na+‐Ca2+ countertransport

J. Henquin, M. Garrino, M. Nenquin, 1985, FEBS letters.

Metabolic control of potassium permeability in pancreatic islet cells.

J. Henquin, 1980, The Biochemical journal.

Effects of acute sodium omission on insulin release, ionic flux and membrane potential in mouse pancreatic B-cells.

J. Henquin, W. Schmeer, M. Nenquin, 1988, Biochimica et biophysica acta.

Opposite effects of intracellular Ca2+ and glucose on K+ permeability of pancreatic islet cells

J. Henquin, 1979, Nature.

Distinct effects of acetylcholine and glucose on 45calcium and 86rubidium efflux from mouse pancreatic islets

J. Henquin, M. Nenquin, P. Awouters, 1984, FEBS letters.

Forskolin, an activator of adenylate cyclase, increases CA2+-dependent electrical activity induced by glucose in mouse pancreatic B cells.

H. Meissner, J. Henquin, W. Schmeer, 1983, Endocrinology.

Possible involvement of a tyrosine kinase-dependent pathway in the regulation of phosphoinositide metabolism by vanadate in normal mouse islets.

J. Henquin, J. Jonas, 1996, The Biochemical journal.

The role of protein kinase-C in signal transduction through vasopressin and acetylcholine receptors in pancreatic B-cells from normal mouse.

P. Gilon, J. Henquin, Z. Gao, 1994, Endocrinology.

Vanadate stimulation of insulin release in normal mouse islets.

P. Gilon, G. Drews, J. Henquin, 1991, The Journal of biological chemistry.

Mechanisms of the stimulation of insulin release by arginine-vasopressin in normal mouse islets.

G. Drews, J. Henquin, T. Plant, 1990, The Journal of biological chemistry.

The GluCre-ROSA26EYFP mouse: a new model for easy identification of living pancreatic alpha-cells.

P. Gilon, P. Herrera, Y. Guiot, 2007, FEBS letters.

Immaturity of insulin secretion by pancreatic islets isolated from one human neonate

J. Henquin, M. Nenquin, 2017, Journal of diabetes investigation.

The electrogenic sodium—potassium pump of mouse pancreatic B‐cells

H. Meissner, J. Henquin, H. Meissner, 1982, The Journal of physiology.

Highly potent and stereoselective effects of the benzoic acid derivative AZ‐DF 265 on pancreatic β‐cells

J. Henquin, M. Garrino, 1988, British journal of pharmacology.

Glucose homeostasis in rats treated acutely and chronically with quinine.

J. Henquin, W. Okitolonda, A. Pottier, 1986, European Journal of Pharmacology.

Absence of effect of culture duration on glucose-activated alterations in intracellular calcium-concentration in mouse pancreatic-islets - Response

P. Gilon, J. Henquin, J. Jonas, 1995 .

Cobalt inhibition of insulin secretion and calcium uptake by isolated rat islets.

J. Henquin, A. Lambert, 1975, The American journal of physiology.

Alloxan-induced alteration of insulin release, rubidium efflux and glucose metabolism in rat islets stimulated by various secretagogues

J. Henquin, P. Malvaux, A. Lambert, 1979, Diabetologia.

Valinomycin inhibition of insulin release and alteration of the electrical properties of pancreatic B cells.

H. Meissner, J. Henquin, 1978, Biochimica et biophysica acta.

Cationic environment and dynamics of insulin secretion. IV. Effect of ouabain.

J. Henquin, P. Malvaux, A. Lambert, 1974, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Adrenaline inhibition of insulin release: role of the repolarization of the B cell membrane

G. Drews, J. Henquin, A. Debuyser, 1991, Pflügers Archiv.

Ionic, Electrical, and Secretory Effects of Inhibitors of Arachidonic Acid Metabolism in Mouse Pancreatic β-Cells

G. Drews, J. Henquin, M. Garrino, 1992, Diabetes.

Relative Importance of Extracellular and Intracellular Ca2+ for Acetylcholine Stimulation of Insulin Release in Mouse Islets

M. Hermans, J. Henquin, M. Hermans, 1989, Diabetes.

Cationic environment and dynamics of insulin secretion. I. Effect of low concentrations of sodium.

J. Henquin, P. Malvaux, A. Lambert, 1974, Endocrinology.

Arginine Vasopressin and Oxytocin Effects in Mouse Pancreatic β-cells: Receptors Involved in Stimulation of Insulin Release

J. Henquin, Z. Gao, Zhi‐yong Gao, 1993, Diabetes.

Imidazoline antagonists of α2‐adrenoceptors increase insulin release in vitro by inhibiting ATP‐sensitive K+ channels in pancreatic β‐cells

J. Henquin, J. Jonas, T. Plant, 1992 .

Insulin release has no absolute requirement for extracellular monovalent ions

M. Hermans, J. Henquin, M. Hermans, 1986, FEBS letters.

Chloride Modulation of Insulin Release, 86Rb+ Efflux, and 45Ca2+ Fluxes in Rat Islets Stimulated by Various Secretagogues

J. Henquin, T. Tamagawa, 1983, Diabetes.

Quinine and the stimulus-secretion coupling in pancreatic beta-cells: glucose-like effects on potassium permeability and insulin release.

J. Henquin, 1982, Endocrinology.

Multisite control of insulin release by glucose.

P. Gilon, J. Henquin, P. Detimary, 1994, Diabete & metabolisme.

Effects of trifluoperazine and pimozide on stimulus-secretion coupling in pancreatic B-cells. Suggestion for a role of calmodulin?

J. Henquin, 1981, The Biochemical journal.

Effects of extracellular adenine nucleotides on the electrical, ionic and secretory events in mouse pancreatic β‐cells

G. Bertrand, J. Henquin, P. Petit, 1989, British journal of pharmacology.

Insulin and insulin-like growth factor 1 antagonize the stimulation of ob gene expression by dexamethasone in cultured rat adipose tissue.

S. Brichard, J. Henquin, B. Reul, 1997, The Biochemical journal.

Cationic environment and dynamics of insulin secretion III. Effect of the absence of potassium

J. Henquin, A. Lambert, 1974, Diabetologia.

Effects of glibenclamide on pancreatic beta-cell proliferation in vivo.

Y. Guiot, J. Henquin, J. Rahier, 1994, European journal of pharmacology.

Clonidine inhibits ATP‐sensitive K+channels in mouse pancreatic β‐cells

J. Henquin, J. Jonas, T. Plant, 1991 .

Comparison of the inhibition of insulin release by activation of adenosine and alpha 2-adrenergic receptors in rat beta-cells.

G. Bertrand, J. Henquin, M. Nenquin, 1989, The Biochemical journal.

Effects of theophylline and dibutyryl cyclic adenosine monophosphate on the membrane potential of mouse pancreatic beta‐cells.

H. Meissner, J. Henquin, 1984, The Journal of physiology.

Oscillations of secretion driven by oscillations of cytoplasmic Ca2+ as evidences in single pancreatic islets.

P. Gilon, J. Henquin, J C Henquin, 1993, The Journal of biological chemistry.

Non-additivity of adrenaline and galanin effects on 86Rb efflux and membrane potential in mouse B-cells suggests sharing of common targets.

G. Drews, J. Henquin, P. Detimary, 1993, Biochimica et biophysica acta.

Adrenaline inhibition of insulin release: role of cyclic AMP

G. Drews, J. Henquin, A. Debuyser, 1991, Molecular and Cellular Endocrinology.

Cold-induced insulin release in vitro: Evidence for exocytosis

J. Henquin, G. Dahl, 1978, Cell and Tissue Research.

Glucose-induced mixed [Ca2+]c oscillations in mouse beta-cells are controlled by the membrane potential and the SERCA3 Ca2+-ATPase of the endoplasmic reticulum.

M. Ravier, P. Gilon, J. Henquin, 2006, American journal of physiology. Cell physiology.

Haeme-oxygenase 1 expression in rat pancreatic beta cells is stimulated by supraphysiological glucose concentrations and by cyclic AMP

Y. Guiot, J. Henquin, J. Rahier, 2003, Diabetologia.

Dibutyryl cyclic AMP triggers Ca2+ influx and Ca2+-dependent electrical activity in pancreatic B cells.

H. Meissner, J. Henquin, 1983, Biochemical and biophysical research communications.

Oral vanadate decreases muscle insulin resistance in obese fa/fa rats

S. Brichard, J. Henquin, L. Ongemba, 1992, Diabetologia.

Long term improvement of glucose homeostasis by vanadate in obese hyperinsulinemic fa/fa rats.

S. Brichard, J. Henquin, Anne-Marie Pottier, 1989, Endocrinology.

The role of vanadium in the management of diabetes.

S. Brichard, J. Henquin, 1995, Trends in pharmacological sciences.

Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function.

P. Gilon, J. Henquin, J C Henquin, 2001, Endocrine reviews.

Atypical Ca2+‐induced Ca2+ release from a sarco‐endoplasmic reticulum Ca2+‐ATPase 3‐dependent Ca2+ pool in mouse pancreatic β‐cells

A. Arredouani, P. Gilon, F. Schuit, 2004, The Journal of physiology.

The muscarinic receptor subtype in mouse pancreatic B‐cells

J. Henquin, M. Nenquin, 1988, FEBS letters.

Tissue-specific correction of lipogenic enzyme gene expression in diabetic rats given vanadate

S. Brichard, J. Girard, J. Henquin, 1994, Diabetologia.

Congenital hyperinsulinism and mosaic abnormalities of the ploidy

C. Junien, C. Sempoux, F. Brunelle, 2005, Journal of Medical Genetics.

Evidence that glucose can control insulin release independently from its action on ATP-sensitive K+ channels in mouse B cells.

P. Gilon, J. Henquin, M. Gembal, 1992, The Journal of clinical investigation.

Identification and subcellular localization of the Na+/H+ exchanger and a novel related protein in the endocrine pancreas and adrenal medulla.

O. Devuyst, Y. Guiot, P. Moulin, 2007, Journal of molecular endocrinology.

Contribution of the endoplasmic reticulum to the glucose-induced [Ca(2+)](c) response in mouse pancreatic islets.

Abdelilah Arredouani, A. Arredouani, P. Gilon, 2002, American journal of physiology. Endocrinology and metabolism.

Cellular composition of the human diabetic pancreas

R. Goebbels, J. Henquin, J. Rahier, 1983, Diabetologia.

Glucose-induced insulin secretion in isolated human islets: Does it truly reflect β-cell function in vivo?

J. Henquin, 2021, Molecular metabolism.

9-Aminoacridine- and tetraethylammonium-induced reduction of the potassium permeability in pancreatic B-cells. Effects on insulin release and electrical properties.

H. Meissner, J. Henquin, M. Preissler, 1979, Biochimica et biophysica acta.

The dual control of insulin secretion by glucose involves triggering and amplifying pathways in β-cells.

J. Henquin, Jean-Claude Henquin, 2011, Diabetes research and clinical practice.

In vivo and in vitro glucose-induced biphasic insulin secretion in the mouse: pattern and role of cytoplasmic Ca2+ and amplification signals in beta-cells.

Myriam Nenquin, B. Ahrén, J. Henquin, 2006, Diabetes.

Muscarinic control of pancreatic B cell function involves sodium-dependent depolarization and calcium influx.

M. Bozem, J. Henquin, J C Henquin, 1988, Endocrinology.

The Oscillatory Behavior of Pancreatic Islets from Mice with Mitochondrial Glycerol-3-phosphate Dehydrogenase Knockout*

M. Ravier, T. Kadowaki, K. Eto, 2000, The Journal of Biological Chemistry.

Control mechanisms of the oscillations of insulin secretion in vitro and in vivo.

M. Ravier, P. Gilon, J. Henquin, 2002, Diabetes.

Potassium dependence of the membrane potential of pancreatic B‐cells

H. Meissner, J. Henquin, M. Preissler, 1978, FEBS letters.

Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release.

Paolo Meda, M. Ravier, K. Willecke, 2005, Diabetes.

Significance of ionic fluxes and changes in membrane potential for stimulus-secretion coupling in pancreatic B-cells

H. Meissner, J. Henquin, J. C. Henquin, 1984, Experientia.

Temporal and Quantitative Correlations Between Insulin Secretion and Stably Elevated or Oscillatory Cytoplasmic Ca2+ in Mouse Pancreatic β-Cells

P. Gilon, J. Henquin, J. Jonas, 1998, Diabetes.

Disorganization of cytoplasmic Ca2+ oscillations and pulsatile insulin secretion in islets from ob/ob mice

M. Ravier, J. Sehlin, J. Henquin, 2002, Diabetologia.

Amplification of insulin secretion by acetylcholine or phorbol ester is independent of β-cell microfilaments and distinct from metabolic amplification

J. Henquin, M. Nenquin, N. Mourad, 2013, Molecular and Cellular Endocrinology.

Inhibition of Protein Synthesis Sequentially Impairs Distinct Steps of Stimulus-secretion Coupling in Pancreatic β Cells* * This work was supported by the Interuniversity Poles of Attraction Program (P4/21), Belgian State Prime Minister's Office, Federal Office for Scientific, Technical, and Cultura

M. Ravier, P. Gilon, J. Henquin, 2001, Endocrinology.

Pronase Effect on Pancreatic Beta Cell Secretion and Morphology

L. Orci, R. Unger, J. Henquin, 1973, Science.

Uptake and Release of Ca2+ by the Endoplasmic Reticulum Contribute to the Oscillations of the Cytosolic Ca2+ Concentration Triggered by Ca2+ Influx in the Electrically Excitable Pancreatic B-cell*

J. Gromada, A. Arredouani, P. Gilon, 1999, The Journal of Biological Chemistry.

Marked Improvement of Glucose Homeostasis in Diabetic ob/ob Mice Given Oral Vanadate

S. Brichard, C. Bailey, J. Henquin, 1990, Diabetes.

Nutrient Control of Insulin Secretion in Isolated Normal Human Islets

Myriam Nenquin, Denis Dufrane, D. Dufrane, 2006, Diabetes.

The influence of temperature on the effects of acetylcholine and adrenaline on the membrane potential and 86Rb efflux in mouse pancreatic B‐cells

G. Drews, J. Henquin, A. Debuyser, 1991, Experimental physiology.

Role of voltage- and Ca2+-dependent K+ channels in the control of glucose-induced electrical activity in pancreatic B-cells

J. Henquin, 1990, Pflügers Archiv.

High Glucose Stimulates Early Response Gene c-Myc Expression in Rat Pancreatic β Cells*

G. Steil, D. R. Laybutt, G. Weir, 2001, The Journal of Biological Chemistry.

35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts.

Thomas J. Smith, B. M. Rasmussen, V. C. Phan, 1999, Diabetologia.

Developmental and nutritional changes of ob and PPAR gamma 2 gene expression in rat white adipose tissue.

S. Brichard, J. Henquin, J. Rahier, 1997, The Biochemical journal.

Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP‐sensitive K+ channels

J. Henquin, M. Nenquin, A. Szollosi, 2010, British journal of pharmacology.

RESEARCH PAPER Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking

J. Henquin, M. Nenquin, A. Szollosi, 2010 .

Glucose-Induced Electrical Activity in β-Cells: Feedback Control of ATP-Sensitive K+ Channels by Ca2+

J. Henquin, 1990, Diabetes.

Stimulation of insulin release by benzoic acid derivatives related to the non-sulphonylurea moiety of glibenclamide: structural requirements and cellular mechanisms.

J. Henquin, M. Garrino, M. Nenquin, 1987, European journal of pharmacology.

Disorganization of cytoplasmic Ca(2+) oscillations and pulsatile insulin secretion in islets from ob/ obmice.

M. Ravier, J. Sehlin, J. Henquin, 2002, Diabetologia.

Influence of organ donor attributes and preparation characteristics on the dynamics of insulin secretion in isolated human islets

J. Henquin, 2018, Physiological reports.

Acute effects of guar gum on glucose tolerance and intestinal absorption of nutrients in rats.

J. Henquin, C. Daumerie, 1982, Diabete & metabolisme.

Alterations of insulin secretion from mouse islets treated with sulphonylureas: perturbations of Ca2+ regulation prevail over changes in insulin content

P. Gilon, J. Henquin, M. Anello, 1999, British journal of pharmacology.

Dynamics and Regulation of Insulin Secretion in Pancreatic Islets from Normal Young Children

J. Henquin, M. Nenquin, 2016, PloS one.

Long term improvement of glucose homeostasis by vanadate treatment in diabetic rats.

S. Brichard, J. Henquin, W. Okitolonda, 1988, Endocrinology.

Insulin, glucagon and somatostatin stores in the pancreas of subjects with type-2 diabetes and their lean and obese non-diabetic controls

J. Henquin, J. Rahier, M. Ibrahim, 2017, Scientific Reports.

Emptying of Intracellular Ca2+ Stores Stimulates Ca2+ Entry in Mouse Pancreatic β‐Cells by Both Direct and Indirect Mechanisms

P. Gilon, J. Henquin, Y. Miura, 1997, The Journal of physiology.

Clonidine inhibits ATP-sensitive K+ channels in mouse pancreatic beta-cells.

J. Henquin, J. Jonas, T. Plant, 1991, British Journal of Pharmacology.

B cell adrenoceptors and sulphonylurea-induced insulin release in mouse islets

J. Henquin, M. Garrino, 1990, Diabetologia.

A tale of two cousins: type 1 and type 2 diabetes.

D. Steiner, E. Ferrannini, C. Boitard, 2005, Diabetes.

Mechanisms of tolbutamide-stimulation of pancreatic B cells — A reply

J. Henquin, 1980, Diabetologia.

Glucose regulation of insulin secretion independent of the opening or closure of adenosine triphosphate-sensitive K+ channels in beta cells.

J. Henquin, Y. Sato, M. Anello, 1999, Endocrinology.

Alteration of lung mechanics by protein-calorie malnutrition in weaned rats.

J. Henquin, M. Kalenga, 1987, Respiration physiology.

Determination of antigen concentration in tissue sections by immunodensitometry.

J. Henquin, J. Rahier, J C Henquin, 1989, Laboratory investigation; a journal of technical methods and pathology.

Effects of chloride deficiency on the pancreatic B-cell response to acetylcholine.

M. Hermans, J. Henquin, W. Schmeer, 1991, Biochimica et Biophysica Acta.

Activation of muscarinic receptors increases the concentration of free Na+ in mouse pancreatic B‐cells

P. Gilon, J. Henquin, 1993, FEBS letters.

Role of the decrease in ionized calcium in the inhibition of insulin release by chloride-free solutions.

M. Hermans, J. Henquin, M. Gerard, 1986, Biochimica et biophysica acta.

Misunderstandings and controversies about the insulin-secreting properties of antidiabetic sulfonylureas.

J. Henquin, 2017, Biochimie.

The GluCre‐ROSA26EYFP mouse: A new model for easy identification of living pancreatic α‐cells

P. Gilon, P. Herrera, Y. Guiot, 2007 .

What ails the β‐cell?

D. Accili, S. Seino, C. Boitard, 2010, Diabetes, obesity & metabolism.

Influence of membrane potential changes on cytoplasmic Ca2+ concentration in an electrically excitable cell, the insulin-secreting pancreatic B-cell.

P. Gilon, J. Henquin, J C Henquin, 1992, The Journal of biological chemistry.

Pharmacological approach to understanding the control of insulin secretion in human islets

V. Gmyr, J. Kerr-Conte, D. Dufrane, 2017, Diabetes, obesity & metabolism.

[Cellular mechanisms of the control of insulin secretion].

J. Henquin, 1990, Archives Internationales de Physiologie et de Biochimie.

The potassium permeability of pancreatic islet cells: mechanisms of control and influence on insulin release.

J. Henquin, 1980, Hormone and metabolic research. Supplement series.

Altered cAMP and Ca2+ signaling in mouse pancreatic islets with glucagon-like peptide-1 receptor null phenotype.

D. Drucker, P. Gilon, F. Schuit, 1999, Diabetes.

Is there a role for osmotic events in the exocytotic release of insulin?

M. Hermans, J. Henquin, 1986, Endocrinology.

β‐Cell research – A decade of rapid growth

D. Accili, D. Steiner, S. Seino, 2009, Diabetes, obesity & metabolism.

Prolonged culture in low glucose induces apoptosis of rat pancreatic beta-cells through induction of c-myc.

D. Scott, D. Pipeleers, H. Heimberg, 2003, Biochemical and biophysical research communications.

Synchronization and entrainment of cytoplasmic Ca2+ oscillations in cell clusters prepared from single or multiple mouse pancreatic islets.

J. Henquin, M. Žarković, 2004, American journal of physiology. Endocrinology and metabolism.

The ionic, electrical, and secretory effects of protein kinase C activation in mouse pancreatic B-cells: studies with a phorbol ester.

M. Bozem, J. Henquin, M. Nenquin, 1987, Endocrinology.

Enkephalins and Endorphins

J. Henquin, 1981 .

Regulation of insulin release by ionic and electrical events in B cells.

J. Henquin, 1987, Hormone research.

Protein Deprivation from the Neonatal Period Impairs Lung Development in the Rat

J. Henquin, M. Kalenga, 1987, Pediatric Research.

Measurements of cytoplasmic Ca2+ in islet cell clusters show that glucose rapidly recruits beta-cells and gradually increases the individual cell response.

J. Henquin, F C Jonkers, J C Henquin, 2001, Diabetes.

Tolbutamide stimulation of pancreatic β‐cells involves both cell recruitment and increase in the individual Ca2+ response

Y. Guiot, J. Henquin, J. Rahier, 2001, British journal of pharmacology.

Influence of cell number on the characteristics and synchrony of Ca2+ oscillations in clusters of mouse pancreatic islet cells

P. Gilon, J. Henquin, J. Jonas, 1999, The Journal of physiology.

Okadaic acid‐induced decrease in the magnitude and efficacy of the Ca2+ signal in pancreatic β cells and inhibition of insulin secretion

P. Gilon, J. Henquin, P. Detimary, 1998, British journal of pharmacology.

Insulin secretion in response to high extracellular calcium is not a pathognomonic feature of insulinoma cells.

F. Pattou, J. Henquin, M. Nenquin, 2017, Diabetes & metabolism.

High glucose and hydrogen peroxide increase c-Myc and haeme-oxygenase 1 mRNA levels in rat pancreatic islets without activating NFκB

A. K. Cardozo, J. Henquin, D. Eizirik, 2005, Diabetologia.

High glucose and hydrogen peroxide increase c-Myc and haeme-oxygenase 1 mRNA levels in rat pancreatic islets without activating NF kappa B (vol 48, pg 496, 2005)

A. K. Cardozo, J. Henquin, D. Eizirik, 2005 .

Haeme-oxygenase 1 expression in rat pancreatic beta cells is stimulated by supraphysiological glucose concentrations and by cyclic AMP

Y. Guiot, J. Henquin, J. Rahier, 2004, Diabetologia.

Insulin secretion in islets from mice with a double knockout for the dense core vesicle proteins islet antigen-2 (IA-2) and IA-2beta.

A. Kubosaki, A. Notkins, J. Henquin, 2008, The Journal of endocrinology.

High glucose and hydrogen peroxide increase c-Myc and haeme-oxygenase 1 mRNA levels in rat pancreatic islets without activating NFκB

A. K. Cardozo, J. Henquin, D. Eizirik, 2005, Diabetologia.

Pancreatic β‐cell mass in European subjects with type 2 diabetes

C. Sempoux, Y. Guiot, R. Goebbels, 2008, Diabetes, obesity & metabolism.

The influence of vanadate on insulin counter-regulatory hormones in obese fa/fa rats.

S. Brichard, J. Henquin, J. Kolanowski, 1991, The Journal of endocrinology.

The dual control of insulin secretion by glucose involves triggering and amplifying pathways in β-cells.

J. Henquin, 2011, Diabetes research and clinical practice.

Oscillations of insulin secretion can be triggered by imposed oscillations of cytoplasmic Ca2+ or metabolism in normal mouse islets.

M. Ravier, P. Gilon, J. Henquin, 1999, Diabetes.

Focal congenital hyperinsulinism managed by medical treatment: a diagnostic algorithm based on molecular genetic screening

C. Nichols, C. Dionisi-Vici, J. Henquin, 2014, Clinical endocrinology.

Abstract of the 68th Meeting (Spring Meeting) 6–9 March 1990, Heidelberg

A. Konnerth, B. Sakmann, P. Jonas, 1990, Pflügers Archiv.

M. Ravier, P. Gilon, J. Henquin, 2001, Endocrinology.

Feedback Control of the ATP-Sensitive K+ Current by Cytosolic Ca2+ Contributes to Oscillations of the Membrane Potential in Pancreatic β-Cells

P. Gilon, J. Henquin, J. Rolland, 2002 .

Functional significance of Ca2+ oscillations in pancreatic beta cells.

P. Gilon, J. Henquin, J C Henquin, 1998, Diabetes & metabolism.