V. Kayser

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Effects of the novel analgesic, cizolirtine, in a rat model of neuropathic pain

M. Hamon, V. Kayser, A. Farré, 2003, Pain.

The selective cholecystokininB receptor antagonist L-365,260 diminishes the expression of naloxone-induced morphine withdrawal symptoms in normal and neuropathic rats.

G. Guilbaud, V. Kayser, J. J. Idänpään-Hekkilä, 1998, Life sciences.

CGRP receptor blockade by MK‐8825 alleviates allodynia in infraorbital nerve‐ligated rats

M. Hamon, V. Kayser, S. Bourgoin, 2015, European journal of pain.

Differential anti-neuropathic pain effects of tetrodotoxin in sciatic nerve- versus infraorbital nerve-ligated rats – Behavioral, pharmacological and immunohistochemical investigations

H. Buschmann, M. Hamon, Alban Latremoliere, 2010, Neuropharmacology.

Estrous and sex variations in vocalization thresholds to hindpaw and tail pressure stimulation in the rat

K. Berkley, G. Guilbaud, V. Kayser, 1996, Brain Research.

Influence of Timing of Administration on the Analgesic Effect of Bupivacaine Infiltration in Carrageenin-injected Rats

G. Guilbaud, V. Kayser, D. Fletcher, 1996, Anesthesiology.

Lack of significant changes in μ, δ opioid binding sites and neutral endopeptidase EC 3.4.24.11 in the brain and spinal cord of arthritic rats

B. Roques, G. Guilbaud, V. Kayser, 1989, Neuropharmacology.

Complete Prevention but Stimulus-dependent Reversion of Morphine Tolerance by the Glycine/NMDA Receptor Antagonist (+)-HA966 in Neuropathic Rats

G. Guilbaud, V. Kayser, D. Christensen, 2000, Anesthesiology.

Evidence for adenosine- and serotonin-mediated antihyperalgesic effects of cizolirtine in rats suffering from diabetic neuropathy

M. Hamon, V. Kayser, A. Farré, 2007, Neuropharmacology.

Differential Implication of Proinflammatory Cytokine Interleukin-6 in the Development of Cephalic versus Extracephalic Neuropathic Pain in Rats

M. Hamon, Alban Latremoliere, A. Mauborgne, 2008, The Journal of Neuroscience.

Differential pharmacological alleviation of oxaliplatin-induced hyperalgesia/allodynia at cephalic versus extra-cephalic level in rodents

M. Hamon, V. Kayser, S. Bourgoin, 2014, Neuropharmacology.

Effects of tapentadol on mechanical hypersensitivity in rats with ligatures of the infraorbital nerve versus the sciatic nerve

M. Hamon, V. Kayser, S. Bourgoin, 2013, European journal of pain.

Deafferentation in the rat increases mechanical nociceptive threshold in the innervated limbs

A. Basbaum, G. Guilbaud, V. Kayser, 1990, Brain Research.

Effects of the analgesic agent tramadol in normal and arthritic rats: comparison with the effects of different opioids, including tolerance and cross-tolerance to morphine.

G. Guilbaud, V. Kayser, J. Besson, 1991, European journal of pharmacology.

Potent antinociceptive effects of Kelatorphan (a highly efficient inhibitor of multiple enkephalin-degrading enzymes) systemically administered in normal and arthritic rats

M. Fournié-Zaluski, B. Roques, G. Guilbaud, 1989, Brain Research.

Lack of cross-tolerance between the antinociceptive effects of systemic morphine and asimadoline, a peripherally-selective κ-opioid agonist, in CCI-neuropathic rats

G. Catheline, G. Guilbaud, V. Kayser, 1999, PAIN®.

Effects of systemic naloxone upon ventrobasal thalamus neuronal responses in arthritic rats

G. Guilbaud, V. Kayser, M. Gautron, 1982, Brain Research.

Opioid receptor types and antinociceptive activity in chronic inflammation: bothe κ- and μ-opiate agonistic effects are enhanced in arthritic rats

J. Besson, G. Guilbaud, V. Kayser, 1986 .

Antinociceptive effect of systemic gabapentin in mononeuropathic rats, depends on stimulus characteristics and level of test integration

V. Kayser, D. Christensen, 2000, Pain.

The antinociceptive effect of combined systemic administration of morphine and the glycine/NMDA receptor antagonist, (+)‐HA966 in a rat model of peripheral neuropathy

G. Guilbaud, V. Kayser, J. Idänpään-Heikkilä, 1998, British journal of pharmacology.

In mononeuropathic rats, the enhancement of morphine antinociception by L-365,260, a selective CCK(B) receptor antagonist, depends on the dose of systemic morphine and stimulus characteristics.

G. Guilbaud, V. Kayser, S. Perrot, 1997, European journal of pharmacology.

Behavioural evidence for a bidirectional effect of systemic naloxone in a model of experimental neuropathy in the rat

N. Attal, G. Guilbaud, V. Kayser, 1989, Brain Research.

The analgesic effects of morphine, but not those of the enkephalinase inhibitor thiorphan, are enhanced in arthritic rats

G. Guilbaud, V. Kayser, 1983, Brain Research.

Dose-dependent analgesic and hyperalgesic effects of systemic naloxone in arthritic rats

G. Guilbaud, V. Kayser, 1981, Brain Research.

Potent and long lasting antinociceptive effects after injection of low doses of a mu-opioid receptor agonist, fentanyl, into the brachial plexus sheath of the rat

G. Guilbaud, V. Kayser, J. Besson, 1990, Pain.

Evidence for a noradrenergic component in the antinociceptive effect of the analgesic agent tramadol in an animal model of clinical pain, the arthritic rat.

J. Besson, G. Guilbaud, V. Kayser, 1992, European journal of pharmacology.

Systemic clonidine differentially modulates the abnormal reactions to mechanical and thermal stimuli in rats with peripheral mononeuropathy

J. Desmeules, G. Guilbaud, V. Kayser, 1995, Pain.

Potent antinociceptive effects of clonidine systemically administered in an experimental model of clinical pain, the arthritic rat

G. Guilbaud, V. Kayser, J. Besson, 1992, Brain Research.

Spinal Cord Transection-Induced Allodynia in Rats – Behavioral, Physiopathological and Pharmacological Characterization

M. Hamon, V. Kayser, S. Bourgoin, 2014, PloS one.

Further evidence for ‘pain-related’ behaviours in a model of unilateral peripheral mononeuropathy

N. Attal, G. Guilbaud, V. Kayser, 1990, Pain.

Differential Behavioral Effects of Peripheral and Systemic Morphine and Naloxone in a Rat Model of Repeated Acute Inflammation

G. Guilbaud, V. Kayser, Serge Perrot, 2001, Anesthesiology.

Antihyperalgesic effects of cizolirtine in diabetic rats: behavioral and biochemical studies

M. Hamon, A. Mauborgne, V. Kayser, 2004, Pain.

Prevention of tolerance to the antinociceptive effects of systemic morphine by a selective cholecystokinin-B receptor antagonist in a rat model of peripheral neuropathy.

G. Guilbaud, V. Kayser, J. Idänpään-Heikkilä, 1997, The Journal of pharmacology and experimental therapeutics.

Behavioural evidence that systemic morphine may modulate a phasic pain-related behaviour in a rat model of peripheral mononeuropathy

N. Attal, G. Guilbaud, V. Kayser, 1991, Pain.

Repeated low doses of morphine do not induce tolerance but increase the opioid antinociceptive effect in rats with a peripheral neuropathy

G. Guilbaud, V. Kayser, A. Neil, 1990, Brain Research.

Combined systemic administration of the glycine/NMDA receptor antagonist, (+)-HA966 and morphine attenuates pain-related behaviour in a rat model of trigeminal neuropathic pain

G. Guilbaud, V. Kayser, M. Gautron, 1999, PAIN®.

The enhancement of morphine antinociception by a CCKB receptor antagonist in the rat depends on the phase of inflammation and the intensity of carrageenin-induced hyperalgesia

G. Guilbaud, V. Kayser, S. Perrot, 1998, Pain.

Peripheral component in the enhanced antinociceptive effect of systemic U-69,593, a kappa-opioid receptor agonist in mononeuropathic rats.

G. Catheline, G. Guilbaud, V. Kayser, 1998, European journal of pharmacology.

The antinociceptive activity of κ- but not δ-opioid receptor agonists is maintained in morphine-tolerant neuropathic rats

G. Catheline, G. Guilbaud, V. Kayser, 1996 .

Further evidence for a peripheral component in the enhanced antinociceptive effect of systemic morphine in mononeuropathic rats: Involvement of κ-, but not δ-opioid receptors

G. Catheline, G. Guilbaud, V. Kayser, 1996 .

Influence of the sympathetic nervous system in the development of abnormal pain-related behaviours in a rat model of neuropathic pain

J. Desmeules, A. Bertrand, G. Guilbaud, 1995, Neuroscience.

Antinociceptive effect of a kappa-opioid receptor agonist that minimally crosses the blood-brain barrier (ICI 204448) in a rat model of mononeuropathy.

G. Guilbaud, V. Kayser, H. Keïta, 1995, European journal of pharmacology.

Evidence for a peripheral component in the enhanced antinociceptive effect of a low dose of systemic morphine in rats with peripheral mononeuropathy

G. Guilbaud, V. Kayser, S. H. Lee, 1995, Neuroscience.

Antinociceptive effect of systemic kelatorphan, in mononeuropathic rats, involves different opioid receptor types.

G. Guilbaud, V. Kayser, S. H. Lee, 1994, European journal of pharmacology.

Differential action of morphine and various opioid agonists on thermal allodynia and hyperalgesia in mononeuropathic rats

J. Desmeules, G. Guilbaud, V. Kayser, 1994, Pain.

Selective opioid receptor agonists modulate mechanical allodynia in an animal model of neuropathic pain

J. Desmeules, G. Guilbaud, V. Kayser, 1993, Pain.

The bidirectional dose-dependent effect of systemic naloxone is also related to the intensity and duration of pain-related disorders: a study in a rat model of peripheral mononeuropathy

N. Attal, G. Guilbaud, V. Kayser, 1990, Brain Research.

The development of pain-related behaviour and opioid tolerance after neuropathy-inducing surgery and sham surgery

V. Kayser, D. Christensen, 2000, PAIN.

The effect of the glycine/NMDA receptor antagonist, (+)-HA966, on morphine dependence in neuropathic rats

G. Guilbaud, V. Kayser, D. Christensen, 2000, Neuropharmacology.

PII: S0304-3959(00)00334-1

V. Kayser, D. Christensen, 2000 .

Differential effects of various doses of morphine and naloxone on two nociceptive test thresholds in arthritic and normal rats

G. Guilbaud, V. Kayser, 1990, Pain.

Low dose of morphine strongly depresses responses of specific nociceptive neurones in the ventrobasal complex of the rat

G. Guilbaud, V. Kayser, M. Gautron, 1983, Pain.

The highly selective δ agonist BUBU induces an analgesic effect in normal and arthritic rat and this action is not affected by repeated administration of low doses of morphine

B. Roques, J. Desmeules, G. Guilbaud, 1993, Brain Research.

Paradoxical hyperalgesic effect of exceedingly low doses of systemic morphine in an animal model of persistent pain (Freund's adjuvant-induced arthritic rats)

G. Guilbaud, V. Kayser, J. Besson, 1987, Brain Research.

Physiological relevance and time course of a tonic endogenous opioid modulation of nociceptive messages, based on the effects of naloxone in a rat model of localized hyperalgesic inflammation

G. Guilbaud, V. Kayser, 1991, Brain Research.

The antimigraine 5‐HT1B/1D receptor agonists, sumatriptan, zolmitriptan and dihydroergotamine, attenuate pain‐related behaviour in a rat model of trigeminal neuropathic pain

M. Hamon, V. Kayser, S. Bourgoin, 2002, British journal of pharmacology.

The influence of the timing of bupivacaine infiltration on the time course of inflammation induced by two carrageenin injections seven days apart

G. Guilbaud, V. Kayser, D. Fletcher, 1997, Pain.

Behavioural and electrophysiological evidence for an analgesic effect of a non-steroidal anti-inflammatory agent, sodium diclofenac

A. Eschalier, N. Attal, G. Guilbaud, 1988, Pain.

Attenuation of pain-related behavior in a rat model of trigeminal neuropathic pain by viral-driven enkephalin overproduction in trigeminal ganglion neurons.

M. Hamon, Alban Latremoliere, A. Mauborgne, 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

The glycine/NMDA receptor antagonist (+)-HA966 enhances the peripheral effect of morphine in neuropathic rats

V. Martinez, V. Kayser, D. Christensen, 2002, Pain.

PII: S0304-3959(02)00270-1

V. Martinez, V. Kayser, D. Christensen, 2002 .

Antinociceptive effect of (S)-N-desmethyl trimebutine against a mechanical stimulus in a rat model of peripheral neuropathy.

G. Guilbaud, V. Kayser, F. Roman, 1999, Life sciences.

Paradoxical effects of low doses of naloxone in experimental models of inflammatory pain.

G. Guilbaud, V. Kayser, J. Besson, 1988, Progress in brain research.

Naloxone induces a bidirectional effect on phasic and "spontaneous" pain-related behaviour in rats with a peripheral mononeuropathy.

N. Attal, G. Guilbaud, V. Kayser, 1990, Progress in clinical and biological research.

Local and remote modifications of nociceptive sensitivity during carrageenin-induced inflammation in the rat

G. Guilbaud, V. Kayser, 1987, Pain.

Repeated low doses of morphine induce a rapid tolerance in arthritic rats but a potentiation of opiate analgesia in normal animals

G. Guilbaud, V. Kayser, A. Neil, 1986, Brain Research.

Antinociceptive effect of systemic PC 12, a prodrug mixed inhibitor of enkephalin-degrading enzymes, in normal and arthritic rats.

M. Fournié-Zaluski, B. Roques, G. Guilbaud, 1993, European journal of pharmacology.

Lack of significant changes in mu, delta opioid binding sites and neutral endopeptidase EC 3.4.24.11 in the brain and spinal cord of arthritic rats.

B. Roques, G. Guilbaud, V. Kayser, 1989, Neuropharmacology.

Effects of intraplantar morphine on paw edema and pain-related behaviour in a rat model of repeated acute inflammation

G. Guilbaud, V. Kayser, S. Perrot, 1999, PAIN.

Behavioural evidence for a peripheral component in the enhanced antinociceptive effect of a low dose of systemic morphine in carrageenin-induced hyperalgesic rats

G. Guilbaud, V. Kayser, Y. L. Chen, 1991, Brain Research.

FURTHER EVIDENCE FOR A PERIPHERAL COMPONENT IN THE ANTINOCICEPTIVE EFFECT OF SYSTEMIC MORPHINE IN RATS WITH PERIPHERAL MONONEUROPATHY: INVOLVEMENT OF κ- OPIOID RECEPTORS

G. Catheline, G. Guilbaud, V. Kayser, 1995 .

Effect of gabapentin and lamotrigine on mechanical allodynia-like behaviour in a rat model of trigeminal neuropathic pain

G. Guilbaud, V. Kayser, M. Gautron, 2001, Pain.

PII: S0304-3959(01)00305-0

G. Guilbaud, V. Kayser, M. Gautron, 2001 .

Differential effects of specific δ and κ opioid receptor antagonists on the bidirectional dose-dependent effect of systemic naloxone in arthritic rats, an experimental model of persistent pain

G. Guilbaud, V. Kayser, I. Cattaneo, 1993, Brain Research.

GABA, but not opioids, mediates the anti-hyperalgesic effects of 5-HT7 receptor activation in rats suffering from neuropathic pain

M. Hamon, V. Kayser, S. Bourgoin, 2012, Neuropharmacology.

Can tolerance to morphine be induced in arthritic rats?

G. Guilbaud, V. Kayser, 1985, Brain Research.

The antinociceptive activity of kappa- but not delta-opioid receptor agonists is maintained in morphine-tolerant neuropathic rats.

G. Catheline, G. Guilbaud, V. Kayser, 1996, European journal of pharmacology.

Opioid receptor types and antinociceptive activity in chronic inflammation: both kappa- and mu-opiate agonistic effects are enhanced in arthritic rats.

G. Guilbaud, V. Kayser, G. Gacel, 1986, European journal of pharmacology.

Single neurone studies of opioid tolerance and dependence at the ventrobasal thalamic level in an experimental model of clinical pain, the arthritic rat

N. Attal, G. Guilbaud, V. Kayser, 1991, Brain Research.

Differential depressive action of two μ and δ opioid ligands on neuronal responses to noxious stimuli in the thalamic ventrobasal complex of rat

G. Guilbaud, V. Kayser, M. Gautron, 1986, Brain Research.

Effects of ES52, an enkephalinase inhibitor, on responses of ventrobasal thalamic neurons in rat

G. Guilbaud, V. Kayser, M. Gautron, 1984, Peptides.

Low dose of morphine microinjected in the ventral periaqueductal gray matter of the rat depresses responses of nociceptive ventrobasal thalamic neurons

G. Guilbaud, V. Kayser, J. Benoist, 1983, Neuroscience Letters.

Further evidence for a strong depressive effect of low doses of morphine on VB thalamic neuronal responses (a study on arthritic rats)

G. Guilbaud, V. Kayser, J. Benoist, 1983, Brain Research.

Depressive effects of morphine and of an enkephalinase inhibitor on responses of ventro-basal thalamic neurones to noxious stimuli.

G. Guilbaud, V. Kayser, M. Gautron, 1983, Life sciences.

Sensitization of the nervous system, induced by two successive hindpaw inflammations, is suppressed by a local anesthetic

G. Guilbaud, V. Kayser, J. Idänpään-Heikkilä, 1998, Brain Research.

Neuronal loss in the ventrobasal complex of the rat thalamus alters behavioral responses to noxious stimulation

M. Peschanski, G. Guilbaud, V. Kayser, 1984, PAIN.

Behavioural and electrophysiological studies on the paradoxical antinociceptive effects of an extremely low dose of naloxone in an animal model of acute and localized inflammation

G. Guilbaud, V. Kayser, M. Gautron, 2004, Experimental Brain Research.

Thresholds and encoding of neuronal responses to mechanical stimuli in the ventro-basal thalamus during carrageenin-induced hyperalgesic inflammation in the rat

G. Guilbaud, V. Kayser, M. Gautron, 2004, Experimental Brain Research.

Initial nociceptive sensitization in carrageenin-induced rat paw inflammation is dependent on amine autacoid mechanisms: electrophysiological and behavioural evidence obtained with a quaternary antihistamine, thiazinamium

G. Guilbaud, V. Kayser, J. Benoist, 2004, Experimental Brain Research.

Neuronal response thresholds to and encoding of thermal stimuli during carrageenin-hyperalgesic-inflammation in the ventro-basal thalamus of the rat

G. Guilbaud, V. Kayser, M. Gautron, 2004, Experimental Brain Research.

Evidence for peripheral serotonergic mechanisms in the early sensitization after carrageenin-induced inflammation: electrophysiological studies in the ventrobasal complex of the rat thalamus using a potent specific antagonist of peripheral 5-HT receptors

A. Eschalier, G. Guilbaud, V. Kayser, 1989, Brain Research.

Modifications in the responsiveness of rat ventrobasal thalamic neurons at different stages of carrageenin-produced inflammation

G. Guilbaud, V. Kayser, M. Gautron, 1986, Brain Research.

Further evidence for changes in the responsiveness of somatosensory neurons in arthritic rats: a study of the posterior intralaminar region of the thalamus

G. Guilbaud, V. Kayser, 1984, Brain Research.

Aspirin clearly depresses responses of ventrobasal thalamus neurons to joint stimuli in arthritic rats

G. Guilbaud, V. Kayser, M. Gautron, 1982, PAIN.

Differential effects of calcitonin gene-related peptide receptor blockade by olcegepant on mechanical allodynia induced by ligation of the infraorbital nerve vs the sciatic nerve in the rat

M. Hamon, V. Kayser, S. Bourgoin, 2012, PAIN®.

Evidence for central phenomena participating in the changes of responses of ventrobasal thalamic neurons in arthritic rats

A. Eschalier, N. Attal, G. Guilbaud, 1989, Brain Research.

Increase in the threshold of a nociceptive test induced by naloxone in morphine-tolerant rats

G. Guilbaud, V. Kayser, 1985, Brain Research.

N‐methyl‐d‐aspartate receptor‐mediated modulations of the anti‐allodynic effects of 5‐HT1B/1D receptor stimulation in a rat model of trigeminal neuropathic pain

M. Hamon, Alban Latremoliere, V. Kayser, 2011, European journal of pain.

Cross-tolerance between analgesic low doses of morphine and naloxone in arthritic rats

G. Guilbaud, V. Kayser, 1987, Brain Research.

Analgesia produced by low doses of the opiate antagonist naloxone in arthritic rats is reduced in morphine-tolerant animals

G. Guilbaud, V. Kayser, J. Besson, 1986, Brain Research.

Altered nociception in mice with genetically induced hypoglutamatergic tone

M. Hamon, V. Kayser, S. Bourgoin, 2015, Neuroscience.

Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A−/−, 5-HT1B−/−, 5-HT2A−/−, 5-HT3A−/− and 5-HTT−/− knock-out male mice

D. Julius, M. Hamon, J. Gingrich, 2007, PAIN.

Influence of a specific 5-HT3 antagonist on carrageenan-induced hyperalgesia in rats

A. Eschalier, G. Guilbaud, V. Kayser, 1989, Pain.

Differential effects of specific delta and kappa opioid receptor antagonists on the bidirectional dose-dependent effect of systemic naloxone in arthritic rats, an experimental model of persistent pain.

G. Guilbaud, V. Kayser, I. Cattaneo, 1993, Brain research.

Further evidence for a peripheral component in the enhanced antinociceptive effect of systemic morphine in mononeuropathic rats: involvement of kappa-, but not delta-opioid receptors.

G. Catheline, G. Guilbaud, V. Kayser, 1996, European journal of pharmacology.

Behavioral evidence for a crossed ascending pathway for pain transmission in the anterolateral quadrant of the rat spinal cord

Marc Peschanski, Valérie Kayser, J. Besson, 1986, Brain Research.

Further evidence for a bidirectional effect of naloxone on the pain threshold in tolerant and non-tolerant arthritic rats

G. Guilbaud, V. Kayser, J. Besson, 1984, Neuropeptides.

Modifications of the opioid system reactivity in Freund's adjuvant induced-arthritic and carrageenin-injected rats, models or chronic and acute inflammatory pain: behavioural and electrophysiological studies

G. Guilbaud, V. Kayser, J. Benoist, 1988, Agents and Actions.