N. Azas

发表

In Vitro Activities of 7-Substituted 9-Chloro and 9-Amino-2-Methoxyacridines and Their Bis- and Tetra-Acridine Complexes against Leishmania infantum

J. Galy, C. Di Giorgio, F. Delmas, 2003, Antimicrobial Agents and Chemotherapy.

Nongenotoxic 3-Nitroimidazo[1,2-a]pyridines Are NTR1 Substrates That Display Potent in Vitro Antileishmanial Activity.

A. Fairlamb, S. Wyllie, N. Azas, 2019, ACS medicinal chemistry letters.

Interaction Forces Drive the Environmental Transmission of Pathogenic Protozoa

D. Aubert, I. Villena, Pierre-henri Puech, 2011, Applied and Environmental Microbiology.

Simultaneous detection of the protozoan parasites Toxoplasma, Cryptosporidium and Giardia in food matrices and their persistence on basil leaves.

D. Aubert, I. Villena, Stéphanie La Carbona, 2016, Food microbiology.

A new, rapid and sensitive bioluminescence assay for drug screening on Leishmania.

D. Parzy, N. Azas, N. Vidal, 2013, Journal of microbiological methods.

A potential acetyltransferase involved in Leishmania major metacaspase-dependent cell death

N. Azas, L. Basmaciyan, M. Casanova, 2019, Parasites & Vectors.

Temporal analysis of the autophagic and apoptotic phenotypes in Leishmania parasites

N. Azas, L. Basmaciyan, L. Berry, 2018, Microbial cell.

A novel hydrolase with a pro-death activity from the protozoan parasite Leishmania major

N. Azas, P. Jacquet, L. Basmaciyan, 2019, Cell Death Discovery.

Calcein+/PI- as an early apoptotic feature in Leishmania

N. Azas, L. Basmaciyan, M. Casanova, 2017, PloS one.

Novel 8-nitroquinolin-2(1H)-ones as NTR-bioactivated antikinetoplastid molecules: Synthesis, electrochemical and SAR study.

A. Fairlamb, S. Wyllie, L. Vendier, 2018, European journal of medicinal chemistry.

No evidence of oxidant events in amphotericin B cytotoxicity versus L. infantum promastigotes.

C. Di Giorgio, F. Delmas, N. Azas, 2001, Parasite.

Macrophages facilitate the excystation and differentiation of Toxoplasma gondii sporozoites into tachyzoites following oocyst internalisation

J. Dubey, D. Ferguson, Pierre-henri Puech, 2016, Scientific Reports.

(De)glutamylation and cell death in Leishmania parasites

N. Azas, L. Basmaciyan, D. Robinson, 2019, PLoS neglected tropical diseases.

Synthesis and evaluation of original amidoximes as antileishmanial agents.

N. Azas, M. Laget, M. Crozet, 2010, Bioorganic & medicinal chemistry.

Transformation of Salmonella typhimurium TA1538 by optimized electroporation

G. Duménil, N. Azas, M. Laget, 1993 .

A New Synthetic Route to Original Sulfonamide Derivatives in 2-Trichloromethylquinazoline Series: A Structure-Activity Relationship Study of Antiplasmodial Activity

S. Rault, N. Azas, P. Vanelle, 2012, Molecules.

Toxicity and genotoxicity of antimalarial alkaloid rich extracts derived from Mitragyna inermis O. Kuntze and Nauclea latifolia

O. Doumbo, C. Di Giorgio, N. Azas, 2000, Phytotherapy research : PTR.

Design, synthesis, and antiprotozoal evaluation of new 2,9‐bis[(substituted‐aminomethyl)phenyl]‐1,10‐phenanthroline derivatives

J. Mergny, R. Das, N. Azas, 2018, Chemical biology & drug design.

Antimalarial activity of extracts and alkaloids isolated from six plants used in traditional medicine in Mali and Sao Tome

C. Di Giorgio, N. Azas, P. Timon-David, 2002, Phytotherapy research : PTR.

Different apoptosis pathways in Leishmania parasites

N. Azas, L. Basmaciyan, M. Casanova, 2018, Cell Death Discovery.

Dynamics of Toxoplasma gondii Oocyst Phagocytosis by Macrophages

J. Dubey, Pierre-henri Puech, N. Azas, 2020, Frontiers in Cellular and Infection Microbiology.

Synthesis and antiplasmodial activity of new 4-aryl-2-trichloromethylquinazolines.

S. Rault, N. Azas, M. Gasquet, 2008, Bioorganic & medicinal chemistry letters.

Design, synthesis, and characterization of novel aminoalcohol quinolines with strong in vitro antimalarial activity.

B. Pradines, N. Azas, M. Marchivie, 2021, European journal of medicinal chemistry.

Design, synthesis, and antiprotozoal evaluation of new 2,4-bis[(substituted-aminomethyl)phenyl]quinoline, 1,3-bis[(substituted-aminomethyl)phenyl]isoquinoline and 2,4-bis[(substituted-aminomethyl)phenyl]quinazoline derivatives

S. Moukha, J. Mergny, R. Das, 2020, Journal of enzyme inhibition and medicinal chemistry.

Design, synthesis and antimalarial activity of novel bis{N-[(pyrrolo[1,2-a]quinoxalin-4-yl)benzyl]-3-aminopropyl}amine derivatives

J. Mergny, R. Das, N. Azas, 2017, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and in vitro antiplasmodial evaluation of 4-anilino-2-trichloromethylquinazolines.

S. Rault, N. Azas, M. Gasquet, 2009, Bioorganic & medicinal chemistry.

Antiparasitic activity of highly conjugated pyrimidine-2,4-dione derivatives.

C. Di Giorgio, F. Delmas, N. Azas, 2003, Farmaco.

1,3-Diphenylpyrazoles: synthesis and antiparasitic activities of azomethine derivatives.

C. Di Giorgio, F. Delmas, N. Azas, 2002, European journal of medicinal chemistry.

Synthesis and evaluation of monoamidoxime derivatives: toward new antileishmanial compounds.

N. Azas, P. Vanelle, Ahlem Bouhlel, 2011, European journal of medicinal chemistry.

Antileishmanial activity of three saponins isolated from ivy, α-hederin, β-hederin and hederacolchiside A1, as compared to their action on mammalian cells cultured in vitro.

F. Delmas, N. Azas, M. Gasquet, 2000 .

Antimalarial activity of crude extracts from nine African medicinal plants.

N. Azas, V. Mahiou-Leddet, E. Ollivier, 2008, Journal of ethnopharmacology.

Original quinazoline derivatives displaying antiplasmodial properties.

N. Azas, M. Laget, P. Vanelle, 2010, European journal of medicinal chemistry.

Discovery of new hit-molecules targeting Plasmodium falciparum through a global SAR study of the 4-substituted-2-trichloromethylquinazoline antiplasmodial scaffold.

N. Azas, H. El-Kashef, P. Vanelle, 2017, European journal of medicinal chemistry.

Targeting the human parasite Leishmania donovani: discovery of a new promising anti-infectious pharmacophore in 3-nitroimidazo[1,2-a]pyridine series.

N. Azas, M. Laget, M. Crozet, 2013, Bioorganic & medicinal chemistry.

Preparation and antiprotozoal evaluation of promising β-carboline alkaloids.

N. Azas, E. Ollivier, P. Vanelle, 2012, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Looking for new antiplasmodial quinazolines: DMAP-catalyzed synthesis of 4-benzyloxy- and 4-aryloxy-2-trichloromethylquinazolines and their in vitro evaluation toward Plasmodium falciparum.

N. Azas, P. Vanelle, N. Primas, 2016, European journal of medicinal chemistry.

4-Thiophenoxy-2-trichloromethyquinazolines display in vitro selective antiplasmodial activity against the human malaria parasite Plasmodium falciparum.

S. Rault, N. Azas, M. Laget, 2011, Bioorganic & medicinal chemistry letters.

Targeting the human malaria parasite Plasmodium falciparum: in vitro identification of a new antiplasmodial hit in 4-phenoxy-2-trichloromethylquinazoline series.

S. Rault, N. Azas, P. Garrigue, 2011, European journal of medicinal chemistry.

Tandem synthesis and in vitro antiplasmodial evaluation of new naphtho[2,1-d]thiazole derivatives.

N. Azas, M. Crozet, P. Vanelle, 2012, European journal of medicinal chemistry.

Synthesis of antiplasmodial 2-aminothieno[3,2-d]pyrimidin-4(3H)-one analogues using the scaffold hopping strategy.

S. Corvaisier, V. Lisowski, N. Azas, 2022, European journal of medicinal chemistry.

Synthesis and Antiprotozoal Activity of 4‐Arylcoumarins.

S. Combes, F. Delmas, N. Azas, 2010 .

Synthesis and antiprotozoal activity of 4-arylcoumarins.

S. Combes, F. Delmas, N. Azas, 2010, European journal of medicinal chemistry.

In Vitro Activities of Position 2 Substitution-Bearing 6-Nitro- and 6-Amino-Benzothiazoles and Their Corresponding Anthranilic Acid Derivatives against Leishmania infantum and Trichomonas vaginalis

J. Galy, C. Di Giorgio, F. Delmas, 2002, Antimicrobial Agents and Chemotherapy.

Activity of benzothiazoles and chemical derivatives on Plasmodium falciparum

J. Galy, C. Di Giorgio, M. Robin, 2004, Parasitology.

Synthesis and Promising in Vitro Antiproliferative Activity of Sulfones of a 5-Nitrothiazole Series

N. Azas, Nadine Azas, M. Crozet, 2012, Molecules.

TDAE-assisted synthesis of new imidazo[2,1-b]thiazole derivatives as anti-infectious agents.

N. Azas, M. Laget, T. Terme, 2010, European journal of medicinal chemistry.

Design, Synthesis and Antimalarial Activity of Some New Aminoalcoholpyrrolo[1,2-a]quinoxaline Derivatives

N. Azas, P. Sonnet, C. Mullié, 2016 .

8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi.

A. Fairlamb, S. Corvaisier, S. Wyllie, 2020, European journal of medicinal chemistry.

Antileishmanial pharmacomodulation in 8-nitroquinolin-2(1H)-one series.

S. Rault, N. Azas, M. Laget, 2015, Bioorganic & medicinal chemistry.

Looking for new antileishmanial derivatives in 8-nitroquinolin-2(1H)-one series.

S. Rault, N. Azas, M. Laget, 2015, European journal of medicinal chemistry.

Synthesis and in vitro evaluation of 4-trichloromethylpyrrolo[1,2-a]quinoxalines as new antiplasmodial agents.

Aurélien Lesnard, S. Rault, N. Azas, 2014, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of novel 4-alkapolyenylpyrrolo[1,2-a]quinoxalines as antileishmanial agents--part III.

P. Le Pape, S. Daulouède, P. Vincendeau, 2014, European journal of medicinal chemistry.

Fagraldehyde, a secoiridoid isolated from Fagraea fragrans.

L. Angenot, G. Dive, R. Faure, 2008, Journal of natural products.

Synthesis and biological evaluation of new heterocyclic quinolinones as anti-parasite and anti-HIV drug candidates.

C. Pannecouque, M. Robin, N. Azas, 2009, Bioorganic & medicinal chemistry letters.

In vitro antiplasmodial activity of some medicinal plants of Burkina Faso

S. Sirima, N. Azas, V. Mahiou-Leddet, 2013, Parasitology Research.

Screening of selected indigenous plants of Cambodia for antiplasmodial activity.

N. Azas, M. Gasquet, P. Timon-David, 2006, Journal of ethnopharmacology.

HPLC quantification of uncarine D and the anti-plasmodial activity of alkaloids from leaves of Mitragyna inermis (Willd.) O. Kuntze.

N. Azas, M. Gasquet, P. Timon-David, 2005, Phytochemical Analysis.

Structure and antiprotozoal activity of triterpenoid saponins from Glinus oppositifolius.

R. Faure, L. Debrauwer, N. Azas, 2000, Planta medica.

Phytochemical and pharmacological study of roots and leaves of Guiera senegalensis J.F. Gmel (Combretaceae).

L. Angenot, N. Azas, E. Ollivier, 2006, Journal of ethnopharmacology.

Ethnobotanical survey and in vitro antiplasmodial activity of plants used in traditional medicine in Burkina Faso.

F. Fumoux, N. Azas, M. Gasquet, 2003, Journal of ethnopharmacology.

ANTIMALARIAL ACTIVITY OF SWARTZIA MADAGASCARIENSIS DESV. (LEGUMINOSAE), COMBRETUM GLUTINOSUM GUILL. & PERR. (COMBRETACEAE) AND TINOSPORA BAKIS MIERS. (MENISPERMACEAE), BURKINA FASO MEDICINAL PLANTS

N. Azas, Y. Traoré, S. Sanon, 2005 .

Antiplasmodial activity of alkaloid extracts from Pavetta crassipes (K. Schum) and Acanthospermum hispidum (DC), two plants used in traditional medicine in Burkina Faso

N. Azas, M. Gasquet, P. Timon-David, 2003, Parasitology Research.

Synergistic in vitro antimalarial activity of plant extracts used as traditional herbal remedies in Mali

C. Di Giorgio, F. Delmas, N. Azas, 2002, Parasitology Research.

Challenges and Tools for In Vitro Leishmania Exploratory Screening in the Drug Development Process: An Updated Review

N. Azas, A. Cohen, 2021, Pathogens.

Antiplasmodial activity and toxicity of crude extracts from alternatives parts of plants widely used for the treatment of malaria in Burkina Faso: contribution for their preservation

S. Sirima, N. Azas, E. Ollivier, 2009, Parasitology Research.

Antimalarial activity of alkaloids isolated from Stephania rotunda.

N. Azas, M. Gasquet, R. Elias, 2007, Journal of ethnopharmacology.

In vitro antiplasmodial activity of Withania frutescens—Solanaceae

N. Azas, E. Ollivier, K. Bekkouche, 2017 .

Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium.

Aurélien Lesnard, S. Rault, N. Azas, 2015, European journal of medicinal chemistry.

Antimalarial compounds from the aerial parts of Flacourtia indica (Flacourtiaceae).

R. Faure, C. Canlet, L. Debrauwer, 2010, Journal of ethnopharmacology.

Treating leishmaniasis in Amazonia, part 2: Multi-target evaluation of widely used plants to understand medicinal practices.

M. Ginouves, G. Prévot, E. Bourreau, 2022, Journal of ethnopharmacology.

Antimalarial activity of sesquiterpene lactones from Vernonia cinerea.

L. Marcourt, R. Faure, N. Azas, 2006, Chemical & pharmaceutical bulletin.

HPLC Analysis of Stephania rotunda Extracts and Correlation with Antiplasmodial Activity

N. Azas, R. Elias, E. Ollivier, 2013, Phytotherapy research : PTR.

Flow Cytometric Detection of LeishmaniaParasites in Human Monocyte-Derived Macrophages: Application to Antileishmanial-Drug Testing

C. Di Giorgio, F. Delmas, N. Azas, 2000, Antimicrobial Agents and Chemotherapy.

New amide alkaloid from the aerial part of Piper capense L.f. (Piperaceae).

C. Canlet, L. Debrauwer, N. Azas, 2010, Fitoterapia.

Mechanics of the Toxoplasma gondii oocyst wall

Pierre Bongrand, Pierre-Henri Puech, J. Dubey, 2013, Proceedings of the National Academy of Sciences.

Tools and methods for detecting and characterizing giardia, cryptosporidium, and toxoplasma parasites in marine mollusks.

D. Aubert, I. Villena, N. Azas, 2013, Journal of food protection.

Synthesis and in vitro evaluation of new 5-substituted 6-nitroimidazooxazoles as antikinetoplastid agents.

R. Docampo, N. Azas, M. Crozet, 2020, European journal of medicinal chemistry.

A New Thienopyrimidinone Chemotype Shows Multistage Activity against Plasmodium falciparum, Including Artemisinin-Resistant Parasites

P. Roques, S. Rault, G. Snounou, 2021, Microbiology spectrum.

Antimalarial activity of sesquiterpene lactones from Vernonia cinerea.

L. Marcourt, R. Faure, N. Azas, 2006, Chemical & pharmaceutical bulletin.

Leishmania infantum promastigotes: flow cytometry as a possible tool for assessing the effects of drugs on cellular functions.

C. Di Giorgio, F. Delmas, N. Azas, 1997, Experimental parasitology.

New antiplasmodial 4-amino-thieno[3,2-d]pyrimidines with improved intestinal permeability and microsomal stability.

S. Corvaisier, V. Lisowski, N. Azas, 2023, European journal of medicinal chemistry.

4-Substituted Thieno[3,2-d]pyrimidines as Dual-Stage Antiplasmodial Derivatives

V. Lisowski, N. Azas, D. Mazier, 2022, Pharmaceuticals.

Synthesis and Antiplasmodial Evaluation of 4-Carboxamido- and 4-Alkoxy-2-Trichloromethyl Quinazolines

N. Azas, P. Vanelle, N. Primas, 2020, Molecules.

Design, Synthesis, and Antiprotozoal Evaluation of New Promising 2,9-Bis[(substituted-aminomethyl)]-4,7-phenyl-1,10-phenanthroline Derivatives, a Potential Alternative Scaffold to Drug Efflux

S. Moukha, J. Mergny, N. Azas, 2022, Pathogens.

Improving Aqueous Solubility and In Vitro Pharmacokinetic Properties of the 3-Nitroimidazo[1,2-a]pyridine Antileishmanial Pharmacophore

S. Corvaisier, N. Azas, B. Courtioux, 2022, Pharmaceuticals.

New series of monoamidoxime derivatives displaying versatile antiparasitic activity.

N. Azas, T. Terme, P. Vanelle, 2014, European journal of medicinal chemistry.

Lowering of 5-nitroimidazole's mutagenicity: towards optimal antiparasitic pharmacophore.

N. Azas, M. Gasquet, M. de Meo, 2009, European journal of medicinal chemistry.

Discovery of a new antileishmanial hit in 8-nitroquinoline series.

S. Rault, N. Azas, M. Laget, 2012, European journal of medicinal chemistry.

Assessment of amphotericin B susceptibility in Leishmania infantum promastigotes by flow cytometric membrane potential assay.

C. Di Giorgio, F. Delmas, N. Azas, 1997, Cytometry.

8-Aryl-6-chloro-3-nitro-2-(phenylsulfonylmethyl)imidazo[1,2-a]pyridines as potent antitrypanosomatid molecules bioactivated by type 1 nitroreductases.

A. Fairlamb, S. Wyllie, N. Azas, 2018, European journal of medicinal chemistry.

In vitro antiplasmodial activity of some medicinal plants of Burkina Faso

S. Sirima, N. Azas, V. Mahiou-Leddet, 2013, Parasitology Research.

Different apoptosis pathways in Leishmania parasites

N. Azas, L. Basmaciyan, M. Casanova, 2018, Cell Death Discovery.

Implication of different domains of the Leishmania major metacaspase in cell death and autophagy

M. Dacher, N. Fasel, N. Azas, 2015, Cell Death and Disease.

Antiplasmodial Activity and Cytotoxicity of Semi Purified Fractions from Zanthoxylum zanthoxyloïdes Lam. Bark of Trunk

N. Azas, E. Ollivier, A. Gansané, 2010 .

A novel hydrolase with a pro-death activity from the protozoan parasite Leishmania major

N. Azas, P. Jacquet, L. Basmaciyan, 2019, Cell Death Discovery.

Antikinetoplastid SAR study in 3-nitroimidazopyridine series: Identification of a novel non-genotoxic and potent anti-T. b. brucei hit-compound with improved pharmacokinetic properties.

A. Fairlamb, S. Corvaisier, S. Wyllie, 2020, European journal of medicinal chemistry.

Anti-HIV and antiplasmodial activity of original flavonoid derivatives.

C. Pannecouque, M. Robin, N. Azas, 2010, Bioorganic & medicinal chemistry.

A potential acetyltransferase involved in Leishmania major metacaspase-dependent cell death

N. Azas, L. Basmaciyan, M. Casanova, 2019, Parasites & Vectors.

6-Chloro-3-nitro-2-[(phenylsulfonyl)methyl]imidazo[1,2-b]pyridazine

N. Azas, B. Courtioux, P. Vanelle, 2023, Molbank.

University of Dundee Nongenotoxic 3-Nitroimidazo [ 1 , 2-a ] pyridines Are NTR 1 Substrates That Display Potent in Vitro Antileishmanial Activity

A. Fairlamb, S. Wyllie, N. Azas, 2019 .

New antiplasmodial alkaloids from Stephania rotunda.

N. Azas, V. Mahiou-Leddet, E. Ollivier, 2013, Journal of ethnopharmacology.

2-Phenoxy-3-Trichloromethylquinoxalines Are Antiplasmodial Derivatives with Activity against the Apicoplast of Plasmodium falciparum

A. Azqueta, N. Azas, F. Benoit‐Vical, 2021, Pharmaceuticals.

Antiplasmodial activity of three bisbenzylisoquinoline alkaloids from the tuber of Stephania rotunda

N. Azas, M. Gasquet, R. Elias, 2010, Natural Product Research.

A decade of Plasmodium falciparum metabolic pathways of therapeutic interest to develop new selective antimalarial drugs.

N. Azas, A. Cohen, A. Dumètre, 2013, Mini reviews in medicinal chemistry.

Synthesis and Antimalarial Activity of New Enantiopure Aminoalcoholpyrrolo[ 1,2-a]quinoxalines.

N. Azas, P. Sonnet, C. Mullié, 2017, Medicinal chemistry.