S. Tilley

发表

Management and sequelae of a 41-year-old jehovah's witness with severe anhydrous ammonia inhalation injury.

B. Cairns, C. Bermudez, Shiara M. Ortiz-Pujols, 2014, Journal of burn care & research : official publication of the American Burn Association.

p16INK4a reporter mice reveal age-promoting effects of environmental toxicants.

N. Sharpless, J. Krishnamurthy, S. Tilley, 2014, The Journal of clinical investigation.

Metabolic hyperemia requires ATP-sensitive K+ channels and H2O2 but not adenosine in isolated mouse hearts.

C. Ledent, S. Tilley, Syed Jamal Mustafa, 2014, American journal of physiology. Heart and circulatory physiology.

Functional and RNA Expression Profile of Adenosine Receptor Subtypes in Mouse Mesenteric Arteries

C. Ledent, T. Krahn, S. Tilley, 2013, Journal of cardiovascular pharmacology.

Adenosine induces airway hyperresponsiveness through activation of A3 receptors on mast cells.

B. Fredholm, X. Hua, D. Deshpande, 2008, The Journal of allergy and clinical immunology.

Cytokines regulate beta-2-adrenergic receptor responsiveness in airway smooth muscle via multiple PKA- and EP2 receptor-dependent mechanisms.

R. Panettieri, Manhong Guo, R. Penn, 2005, Biochemistry.

Targeting the Canonical Nuclear Factor-κB Pathway with a High-Potency IKK2 Inhibitor Improves Outcomes in a Mouse Model of Idiopathic Pneumonia Syndrome.

J. Serody, A. Baldwin, A. Panoskaltsis-Mortari, 2017, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

X. Hua, D. Dixon, B. Koller, 2007, The Journal of Immunology.

Human embryonic stem cells: a source of mast cells for the study of allergic and inflammatory diseases.

B. Koller, S. Tilley, A. Latour, 2010, Blood.

Contributions of A2A and A2B adenosine receptors in coronary flow responses in relation to the KATP channel using A2B and A2A/2B double-knockout mice.

C. Ledent, T. Krahn, S. Tilley, 2011, American journal of physiology. Heart and circulatory physiology.

Contributions of A2A and A2B adenosine receptors in coronary flow responses in relation to the KATP channel using A2B and A2A/2B double-knockout mice.

C. Ledent, T. Krahn, S. Tilley, 2011, American journal of physiology. Heart and circulatory physiology.

Pulmonary immune responses to Propionibacterium acnes in C57BL/6 and BALB/c mice.

X. Hua, W. Funkhouser, A. Ghio, 2006, American journal of respiratory cell and molecular biology.

Involvement of A 1 adenosine receptors in altered vascular responses and inflammation in an allergic mouse model of asthma

A. Nadeem, S. Tilley, Syed Jamal Mustafa, 2010 .

Involvement of A1 adenosine receptors in altered vascular responses and inflammation in an allergic mouse model of asthma.

A. Nadeem, S. Tilley, Syed Jamal Mustafa, 2010, American journal of physiology. Heart and circulatory physiology.

Involvement of NADPH oxidase in A2A adenosine receptor-mediated increase in coronary flow in isolated mouse hearts

C. Ledent, S. Tilley, Syed Jamal Mustafa, 2015, Purinergic Signalling.

Interactions between A2A adenosine receptor, hydrogen peroxide, and KATP channel in coronary reactive hyperemia

C. Ledent, S. Tilley, Syed Jamal Mustafa, 2012, American journal of physiology. Heart and circulatory physiology.

A1 adenosine receptor negatively modulates coronary reactive hyperemia via counteracting A2A-mediated H2O2 production and KATP opening in isolated mouse hearts.

S. Tilley, Syed Jamal Mustafa, Xueping Zhou, 2013, American journal of physiology. Heart and circulatory physiology.

MyD88 provides a protective role in long-term radiation-induced lung injury

X. Hua, J. Ting, S. Kirby, 2012, International journal of radiation biology.

Restrictive Lung Disease

S. Tilley, Craig N. Rosebrock, 2009 .

Identification of A3 Receptor- and Mast Cell-Dependent and -Independent Components of Adenosine-Mediated Airway Responsiveness in Mice1

M. Tsai, S. Galli, B. Koller, 2003, The Journal of Immunology.

Responsiveness in Mice Components of Adenosine-Mediated Airway Cell-Dependent and-Independent Receptor-and Mast 3 Identification of

M. Tsai, S. Galli, B. Koller, 2003 .

Digital Inhalers for Asthma or Chronic Obstructive Pulmonary Disease: A Scientific Perspective

R. Pleasants, S. Schworer, R. Dhand, 2021, Pulmonary Therapy.

Enhanced mast cell activation in mice deficient in the A2b adenosine receptor

X. Hua, B. Koller, S. Tilley, 2007, The Journal of experimental medicine.

Activation of Murine Lung Mast Cells by the Adenosine A3 Receptor 1

M. Jacobson, S. Tilley, M. Blackburn, 2003, The Journal of Immunology.

Receptors for prostaglandin E(2) that regulate cellular immune responses in the mouse.

B. Koller, T. Coffman, R. Mannon, 2001, The Journal of clinical investigation.

Modulatory role for retinoid-related orphan receptor alpha in allergen-induced lung inflammation.

J. Collins, D. Dixon, H. S. Kang, 2006, American journal of respiratory and critical care medicine.

Modulatory Role for Retinoid-related Orphan Receptor α in Allergen-induced Lung Inflammation

J. Collins, D. Dixon, H. S. Kang, 2006 .

Receptors and Signaling Mechanisms Required for Prostaglandin E2-Mediated Regulation of Mast Cell Degranulation and IL-6 Production1

D. Dombrowicz, L. Audoly, B. Koller, 2002, The Journal of Immunology.

Therapeutic Applications

S. Tilley, M. Picher, J. Volmer, 2011, Sub-cellular biochemistry.

Exacerbation of allergic inflammation in mice exposed to diesel exhaust particles prior to viral infection

X. Hua, I. Jaspers, S. Tilley, 2009, Particle and Fibre Toxicology.

Characterization of NLRP12 during the Development of Allergic Airway Disease in Mice

J. Ting, I. C. Allen, J. Arthur, 2012, PloS one.

Staphylococcus aureus α-hemolysin mediates virulence in a murine model of severe pneumonia through activation of the NLRP3 inflammasome.

Robin R. Chamberland, I. C. Allen, S. Tilley, 2012, The Journal of infectious diseases.

Mast Cell Deficiency Limits the Development of Chronic Rhinosinusitis in Mice

X. Hua, S. Graham, B. Senior, 2016, The Annals of otology, rhinology, and laryngology.

Involvement of A1 adenosine receptors and neural pathways in adenosine-induced bronchoconstriction in mice.

X. Hua, D. Deshpande, R. Penn, 2007, American journal of physiology. Lung cellular and molecular physiology.

Identification of an ATP/P2X7/mast cell pathway mediating ozone-induced bronchial hyperresponsiveness

X. Hua, S. Randell, I. Jaspers, 2021, JCI insight.

Analysis of NLRP3 in the Development of Allergic Airway Disease in Mice

X. Hua, B. Koller, J. Ting, 2012, The Journal of Immunology.

Allergic Airway Disease in Mice Analysis of NLRP3 in the Development of

X. Hua, B. Koller, I. C. Allen, 2022 .

The chemokine, CCL3, and its receptor, CCR1, mediate thoracic radiation-induced pulmonary fibrosis.

X. Hua, R. Horuk, S. Kirby, 2011, American journal of respiratory cell and molecular biology.

Impaired bone marrow B-cell development in mice with a bronchiolitis obliterans model of cGVHD.

J. Serody, B. Blazar, S. Tilley, 2018, Blood advances.

Neuropilin‐2 regulates airway inflammation in a neutrophilic asthma model

R. Immormino, T. Moran, S. Tilley, 2021, Immunity, inflammation and disease.

Adenosine A2A receptor and vascular response: role of soluble epoxide hydrolase, adenosine A1 receptor and angiotensin-II

C. Ledent, C. Morisseau, S. Tilley, 2021, Molecular and Cellular Biochemistry.

Ocular Inflammatory Responses in the EP2 and EP4 Receptor Knockout Mice

C. Paterson, S. Tilley, B. Koller, 2006, Ocular immunology and inflammation.

IL-6 Production Regulation of Mast Cell Degranulation and -Mediated2 Required for Prostaglandin E Receptors and Signaling Mechanisms

D. Dombrowicz, L. Audoly, B. Koller, 2002 .

Receptors and pathways mediating the effects of prostaglandin E2 on airway tone.

B. Koller, J. Stock, R. Panettieri, 2003, American journal of physiology. Lung cellular and molecular physiology.

Role of Adenosine Receptor(s) in the Control of Vascular Tone in the Mouse Pudendal Artery

C. Ledent, S. Tilley, Syed Jamal Mustafa, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Evidence for the involvement of NADPH oxidase in adenosine receptor-mediated control of coronary flow using A1 and A3 knockout mice

S. Tilley, M. El-Awady, Syed Jamal Mustafa, 2013, Physiological reports.

Angiotensin II stimulation alters vasomotor response to adenosine in mouse mesenteric artery: role for A1 and A2B adenosine receptors

S. Tilley, M. Nayeem, S. Mustafa, 2015, British journal of pharmacology.

Noninvasive real-time measurement of nasal mucociliary clearance in mice by pinhole gamma scintigraphy.

X. Hua, W. Bennett, B. Senior, 2010, Journal of applied physiology.

Human embryonic stem cells: a source of mast cells for the study of allergic and inﬂammatory diseases

B. Koller, S. Tilley, A. Latour, 2010 .

Neuropilin-2 regulates airway inflammatory responses to inhaled lipopolysaccharide.

M. Hernandez, R. Immormino, N. Alexis, 2018, American journal of physiology. Lung cellular and molecular physiology.

The FcεRIβ homologue, MS4A4A, promotes FcεRI signal transduction and store-operated Ca2+ entry in human mast cells.

G. Cruse, D. Metcalfe, S. Tilley, 2020, Cellular signalling.

Role of (cid:1) -hydroxylase in adenosine-mediated aortic response through MAP kinase using A 2A -receptor knockout mice

C. Ledent, D. Zeldin, S. Tilley, 2012 .

Role of (cid:1) -hydroxylase in adenosine-mediated aortic response through MAP kinase using A 2A -receptor knockout mice

C. Ledent, D. Zeldin, S. Tilley, 2012 .

Integrating digital inhalers into clinical care of patients with asthma and chronic obstructive pulmonary disease.

R. Pleasants, S. Schworer, R. Dhand, 2022, Respiratory medicine.

Rib Fractures and Death from Deletion of Osteoblast βcatenin in Adult Mice Is Rescued by Corticosteroids

Yueh Z. Lee, Arjun Deb, M. Rojas, 2013, PloS one.

CYP-epoxygenases contribute to A2A receptor-mediated aortic relaxation via sarcolemmal KATP channels.

C. Ledent, S. Tilley, M. Nayeem, 2012, American journal of physiology. Regulatory, integrative and comparative physiology.

E-Prostanoid-3 Receptors Mediate the Proinflammatory Actions of Prostaglandin E2 in Acute Cutaneous Inflammation1

B. Koller, J. Stock, J. Mcneish, 2004, The Journal of Immunology.

in Acute Cutaneous Inflammation 2 Proinflammatory Actions of Prostaglandin E E-Prostanoid-3 Receptors Mediate the

B. Koller, J. Stock, J. Mcneish, 2004 .

NADPH Oxidase Pathway Is Involved in Aortic Contraction Induced by A3 Adenosine Receptor in Mice

S. Tilley, M. El-Awady, Syed Jamal Mustafa, 2011, Journal of Pharmacology and Experimental Therapeutics.

Role of EP(2) and EP(3) PGE(2) receptors in control of murine renal hemodynamics.

L. Audoly, T. Coffman, W. Arendshorst, 2001, American journal of physiology. Heart and circulatory physiology.

Identification of specific EP receptors responsible for the hemodynamic effects of PGE2.

L. Audoly, B. Koller, J. Stock, 1999, American journal of physiology. Heart and circulatory physiology.

Modulation of murine dendritic cell function by adenine nucleotides and adenosine: Involvement of the A2B receptor

X. Hua, C. Ledent, J. Boeynaems, 2008, European journal of immunology.

Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes.

B. Koller, T. Coffman, S. Tilley, 2001, The Journal of clinical investigation.

Development of chronic bronchitis and emphysema in beta-epithelial Na+ channel-overexpressing mice.

A. Livraghi, R. Boucher, J. Harkema, 2008, American journal of respiratory and critical care medicine.

Meta-analytical association between angiotensin-converting enzyme gene polymorphisms and sarcoidosis risk.

S. Tilley, H. Kong, W. Xie, 2015, Genetics and molecular research : GMR.

Topical Adenosine Inhibits Inflammation and Mucus Production in Viral Acute Rhinosinusitis

S. Varga, S. Tilley, Kody A. Waldstein, 2022, The Laryngoscope.

Disruption of the A3 Adenosine Receptor Gene in Mice and Its Effect on Stimulated Inflammatory Cells*

Beverly H. Koller, B. Koller, M. Jacobson, 2000, The Journal of Biological Chemistry.

Reproductive failure and reduced blood pressure in mice lacking the EP2 prostaglandin E2 receptor.

H. S. Kim, L. Audoly, B. Koller, 1999, The Journal of clinical investigation.

Identification of specific EP receptors responsible for the hemodynamic effects of PGE2.

L. Audoly, J. Stock, J. Mcneish, 1999, The American journal of physiology.

Identiﬁcation of speciﬁc EP receptors responsible for the hemodynamic effects of PGE 2

L. Audoly, B. Koller, J. Stock, 1999 .

Adenosine and inosine increase cutaneous vasopermeability by activating A(3) receptors on mast cells.

M. Jacobson, S. Tilley, V. Wagoner, 2000, The Journal of clinical investigation.

Methylxanthines in asthma.

S. Tilley, 2011, Handbook of experimental pharmacology.

Targeting the Canonical NF-κB Pathway with a High Potency IKK2 Inhibitor Improves Outcomes in a Mouse Model of Idiopathic Pneumonia Syndrome

J. Serody, A. Baldwin, S. Tilley, 2017 .

Increased plasma mannose binding lectin levels are associated with bronchiolitis obliterans after lung transplantation

S. Tilley, R. Aris, I. Neuringer, 2012, Respiratory Research.

COX-2-derived prostacyclin protects against bleomycin-induced pulmonary fibrosis.

G. FitzGerald, L. Audoly, B. Koller, 2006, American journal of physiology. Lung cellular and molecular physiology.

Prostaglandin E2 protects lower airways against bronchoconstriction.

L. Audoly, B. Koller, A. Lovgren, 2006, American journal of physiology. Lung cellular and molecular physiology.

Blood-aqueous barrier in prostaglandin EP2 receptor knockout mice

B. Koller, C. Paterson, S. Tilley, 2002, Ocular immunology and inflammation.

Both Duration and Pack-years of Tobacco Smoking Should be Used for Clinical Practice and Research.

R. Pleasants, S. Bhatt, S. Tilley, 2020, Annals of the American Thoracic Society.

A1 antagonism in asthma: better than coffee?

R. Boucher, S. Tilley, 2005, The Journal of clinical investigation.

Deficiency of RAMP1 Attenuates Antigen-Induced Airway Hyperresponsiveness in Mice

X. Hua, K. Caron, M. Krummel, 2014, PloS one.

In vivo assessment of coronary flow and cardiac function after bolus adenosine injection in adenosine receptor knockout mice

C. Ledent, S. Tilley, Syed Jamal Mustafa, 2016, Physiological reports.

Testicular Expression of Adora3i2 in Adora3 Knockout Mice Reveals a Role of Mouse A3Ri2 and Human A3Ri3 Adenosine Receptors in Sperm*

Lindsey A. Burnett, B. Hille, J. Unadkat, 2010, The Journal of Biological Chemistry.

Photochemically Altered Air Pollution Mixtures and Contractile Parameters in Isolated Murine Hearts before and after Ischemia

W. Cascio, H. Tong, I. Jaspers, 2013, Environmental health perspectives.

Nasal priming by a murine coronavirus provides protective immunity against lethal heterologous virus pneumonia.

Nitin A. Pagedar, S. Perlman, R. Vijay, 2018, JCI insight.

Identification of BPIFA1/SPLUNC1 as an epithelium-derived smooth muscle relaxing factor

M. Redinbo, N. Alexis, R. Tarran, 2017, Nature Communications.

Reduced coronary reactive hyperemia in mice was reversed by the soluble epoxide hydrolase inhibitor (t-AUCB): Role of adenosine A2A receptor and plasma oxylipins.

C. Ledent, J. Falck, D. Zeldin, 2017, Prostaglandins & other lipid mediators.

Enhanced mast cell activation in mice deficient in the A2b adenosine receptor

X. Hua, B. Koller, S. Tilley, 2007, Journal of Experimental Medicine.

Gs-Coupled Adenosine Receptors Differentially Limit Antigen-Induced Mast Cell Activation

X. Hua, C. Ledent, S. Tilley, 2013, The Journal of Pharmacology and Experimental Therapeutics.

IL-4 Amplifies the Pro-Inflammatory Effect of Adenosine in Human Mast Cells by Changing Expression Levels of Adenosine Receptors

X. Hua, S. Tilley, K. Chason, 2011, PloS one.

Mechanisms underlying uridine adenosine tetraphosphate-induced vascular contraction in mouse aorta: Role of thromboxane and purinergic receptors.

S. Tilley, Syed Jamal Mustafa, Changyan Sun, 2015, Vascular pharmacology.

Involvement of COX-1 in A3 adenosine receptor-mediated contraction through endothelium in mice aorta.

A. Nadeem, S. Tilley, Syed Jamal Mustafa, 2007, American journal of physiology. Heart and circulatory physiology.

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S. Tilley, M. El-Awady, D. Fil, 2011 .

Involvement of NADPH oxidase in A2A adenosine receptor-mediated increase in coronary flow in isolated mouse hearts

C. Ledent, S. Tilley, Syed Jamal Mustafa, 2015, Purinergic Signalling.

Cleavage of high-molecular-weight kininogen by elastase and tryptase is inhibited by ferritin.

M. Willingham, X. Hua, R. D'Agostino, 2008, American journal of physiology. Lung cellular and molecular physiology.

Identification of redundancy between human FcεRIβ and MS4A6A proteins points toward additional complex mechanisms for FcεRI trafficking and signaling

G. Cruse, P. Bradding, S. Tilley, 2022, Allergy.

Adenosine increases nasal mucociliary clearance rate in mice through A2A and A2B adenosine receptors

X. Hua, C. Ledent, W. Bennett, 2013, The Laryngoscope.

Meta-analytical association between angiotensin-converting enzyme gene polymorphisms and sarcoidosis risk.

Hong Wang, W. Xie, S. Tilley, 2015, Genetics and molecular research : GMR.

Identification of specific EP receptors responsible for the hemodynamic effects of PGE2.

L. Audoly, B. Koller, J. Stock, 1999, American journal of physiology. Heart and circulatory physiology.

Contributions of A 2 A and A 2 B adenosine receptors in coronary flow responses in relation to the KATP channel using A 2 B and A 2 A / 2 B double-knockout mice

C. Ledent, T. Krahn, S. Tilley, 2011 .

Mechanisms underlying uridine adenosine tetraphosphate-induced vascular contraction in mouse aorta: Role of thromboxane and purinergic receptors.

S. Tilley, Syed Jamal Mustafa, Changyan Sun, 2015, Vascular pharmacology.