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A. Blei, J. Córdoba, 1995, Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

1404 DIAGNOSIS, PREVALENCE, AND PROGNOSIS OF ACUTE-ON- CHRONIC LIVER FAILURE (ACLF): RESULTS OF THE EASL-CHRONIC LIVER FAILURE (CLIF) CONSORTIUM CANONIC STUDY

R. Moreau, R. Jalan, J. Trebicka, 2012 .

Hepatitis C virus infection in renal transplant recipients: epidemiology, clinical impact, serological confirmation and viral replication.

S. Sauleda, J. Vila, J. Esteban, 1995, Journal of hepatology.

Satavaptan treatment for ascites in patients with cirrhosis: a meta-analysis of effect on hepatic encephalopathy development

H. Vilstrup, P. Ginès, J. Córdoba, 2013, Metabolic Brain Disease.

Alfapump® system vs. large volume paracentesis for refractory ascites: A multicenter randomized controlled study.

R. Jalan, D. Valla, M. Stepanova, 2017, Journal of hepatology.

EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure.

M. Manns, D. Samuel, A. Dhawan, 2017, Journal of hepatology.

230 Usefulness of the measurement of critical flicker frequency in the diagnosis of minimal hepatic encephalopathy (MHE)

V. Felipo, R. Jover, J. Córdoba, 2006 .

Neuropsychological abnormalities in cirrhosis include learning impairment.

R. Esteban, J. Guàrdia, J. Córdoba, 2006, Journal of hepatology.

The development of low-grade cerebral edema in cirrhosis is supported by the evolution of (1)H-magnetic resonance abnormalities after liver transplantation.

À. Rovira, C. Margarit, J. Alonso, 2001, Journal of hepatology.

Functional abnormalities of the motor tract in the rat after portocaval anastomosis and after carbon tetrachloride induction of cirrhosis

N. Chatauret, Gemma Odena, J. Córdoba, 2006, Metabolic Brain Disease.

Stenosis of a portacaval anastomosis affects circadian locomotor activity in the rat: a multivariable analysis.

A. Blei, J. Gottstein, J. Córdoba, 1997, American journal of physiology. Gastrointestinal and liver physiology.

Encephalopathy and liver transplantation

J. Córdoba, L. Chavarria, 2012, Metabolic Brain Disease.

A Long-Term Study of Changes in the Volume of Brain Ventricles and White Matter Lesions After Successful Liver Transplantation

F. X. Aymerich, À. Rovira, J. Alonso, 2010, Transplantation.

Brain magnetic resonance in hepatic encephalopathy.

À. Rovira, J. Alonso, J. Córdoba, 2014, Seminars in ultrasound, CT, and MR.

New assessment of hepatic encephalopathy.

J. Córdoba, Juan Córdoba, 2011, Journal of hepatology.

Improvement of magnetic resonance spectroscopic abnormalities but not pallidal hyperintensity followed amelioration of hepatic encephalopathy after occlusion of a large spleno-renal shunt.

À. Rovira, J. Alonso, J. Córdoba, 2001, Journal of hepatology.

Effects of Branched-Chain Amino Acids Supplementation in Patients With Cirrhosis and a Previous Episode of Hepatic Encephalopathy: A Randomized Study

M. Vergara, R. Esteban, B. Mínguez, 2011, The American Journal of Gastroenterology.

Branched-chain amino acids for people with hepatic encephalopathy.

G. Marchesini, H. Vilstrup, L. Gluud, 2015, The Cochrane database of systematic reviews.

Bacterial infections in cirrhosis: a position statement based on the EASL Special Conference 2013.

F. Lammert, A. Burroughs, R. Moreau, 2014, Journal of hepatology.

Clinical Course of acute‐on‐chronic liver failure syndrome and effects on prognosis

A. de Gottardi, R. Moreau, R. Jalan, 2015, Hepatology.

Hepatic encephalopathy in chronic liver disease: 2014 practice guideline by the European Association for the Study of the Liver and the American Association for the Study of Liver Diseases.

J. Talwalkar, H. Conjeevaram, F. Zoulim, 2014, Journal of hepatology.

Magnetic resonance imaging measurement of brain edema in patients with liver disease: resolution after transplantation

À. Rovira, J. Alonso, J. Córdoba, 2002, Current opinion in neurology.

Value of the critical flicker frequency in patients with minimal hepatic encephalopathy

Manuel Romero-Gómez, Carmina Montoliu, Vicente Felipo, 2007, Hepatology.

High prevalence of sleep disturbance in cirrhosis

P. Penev, A. Blei, J. Córdoba, 1998, Hepatology.

Validity of the Spanish version of the Chronic Liver Disease Questionnaire (CLDQ) as a standard outcome for quality of life assessment

O. Garin, M. Ferrer, R. Esteban, 2006, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

Quality of life and cognitive function in hepatitis C at different stages of liver disease.

S. Sauleda, J. Esteban, R. Esteban, 2003, Journal of hepatology.

MR Imaging Findings in Hepatic Encephalopathy

À. Rovira, J. Alonso, J. Córdoba, 2008, American Journal of Neuroradiology.

Managing complications in cirrhotic patients

D. Valla, P. Angeli, J. Córdoba, 2015, United European gastroenterology journal.

Development of a clinical hepatic encephalopathy staging scale

F. Pujadas, R. Esteban, J. Guàrdia, 2007, Alimentary pharmacology & therapeutics.

Characteristics, risk factors, and mortality of cirrhotic patients hospitalized for hepatic encephalopathy with and without acute-on-chronic liver failure (ACLF).

M. Pavesi, V. Arroyo, P. Angeli, 2014, Journal of hepatology.

Magnetic resonance of the brain in chronic and acute liver failure

J. Córdoba, L. Chavarria, 2013, Metabolic Brain Disease.

Reprint of: Neuroimaging in acute liver failure

À. Rovira, J. Alonso, J. Córdoba, 2012, Neurochemistry International.

Neuroimaging in acute liver failure

À. Rovira, J. Alonso, J. Córdoba, 2011, Neurochemistry International.

Normalization of T2 signal abnormalities in hemispheric white matter with liver transplant

À. Rovira, J. Alonso, J. Córdoba, 2002, Neurology.

Minimal hepatic encephalopathy: diagnosis, clinical significance and recommendations.

J. Córdoba, Juan Córdoba, María Ortiz, 2005, Journal of hepatology.

Brain Magnetic Resonance Spectroscopy in Episodic Hepatic Encephalopathy

À. Rovira, J. Alonso, J. Córdoba, 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Glutamine, myo‐inositol, and organic brain osmolytes after portocaval anastomosis in the rat: Implications for ammonia‐induced brain edema

A. Blei, J. Gottstein, J. Córdoba, 1996, Hepatology.

Normal protein diet for episodic hepatic encephalopathy: results of a randomized study.

R. Esteban, J. Guàrdia, J. Córdoba, 2004, Journal of hepatology.

Hepatic Encephalopathy in Chronic Liver Disease: 2014 Practice Guideline by AASLD and EASL

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CASE REPORT: Usefulness of Magnetic Resonance Spectroscopy for Diagnosis of Hepatic Encephalopathy in a Patient with Relapsing Confusional Syndrome

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Hepatic encephalopathy is associated with posttransplant cognitive function and brain volume

À. Rovira, J. Alonso, J. Córdoba, 2011, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

Patients with refractory ascites treated with alfapump® system have better health-related quality of life as compared to those treated with large volume paracentesis: the results of a multicenter randomized controlled study

R. Jalan, D. Valla, M. Stepanova, 2018, Quality of Life Research.

AASLD PRACTICE GUIDELINE Hepatic Encephalopathy in Chronic Liver Disease: 2014 Practice Guideline by the American Association for the Study of Liver Diseases and the European Association for the Study of the Liver

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Transplanted Oligodendrocytes and Motoneuron Progenitors Generated from Human Embryonic Stem Cells Promote Locomotor Recovery After Spinal Cord Transection

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Cerebellar neurodegeneration in a new rat model of episodic hepatic encephalopathy

M. Vila, J. Genescà, J. Córdoba, 2017, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Minimal hepatic encephalopathy and critical flicker frequency are associated with survival of patients with cirrhosis.

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Validation of the Psychometric Hepatic Encephalopathy Score (PHES) for Identifying Patients with Minimal Hepatic Encephalopathy

A. Duarte-Rojo, J. Córdoba, A. Torre, 2011, Digestive Diseases and Sciences.

Review article: the design of clinical trials in hepatic encephalopathy – an International Society for Hepatic Encephalopathy and Nitrogen Metabolism (ISHEN) consensus statement

R. Butterworth, M. Morgan, J. Bajaj, 2011, Alimentary pharmacology & therapeutics.

Prognostic Assessment in Patients with Hepatic Encephalopathy

J. Córdoba, R. García-Martínez, M. Simón-Talero, 2011, Disease markers.

Variations in the Promoter Region of the Glutaminase Gene and the Development of Hepatic Encephalopathy in Patients With Cirrhosis

C. Montoliu, J. D. del Campo, J. Navarro, 2010, Annals of Internal Medicine.

Treatment of hepatic encephalopathy

M. Vergara, B. Mínguez, J. Córdoba, 1997, The Lancet.

AHnuclearmagnetic resonance-basedmetabonomic approach for grading hepatic encephalopathyandmonitoring the e¡ects of therapeutic hypothermia in rats

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Neuropsychological characterization and detection of subclinical hepatic encephalopathy.

C. Randolph, M. McCrea, A. Blei, 1996, Archives of neurology.

Biexponential Analysis of Diffusion-Tensor Imaging of the Brain in Patients with Cirrhosis before and after Liver Transplantation

F. X. Aymerich, À. Rovira, J. Alonso, 2011, American Journal of Neuroradiology.

T2 hyperintensity along the cortico‐spinal tract in cirrhosis relates to functional abnormalities

À. Rovira, J. Alonso, J. Córdoba, 2003, Hepatology.

Melatonin Arrhythmia Is Corrected After Liver Transplantation

A. Blei, J. Córdoba, P. Steindl, 2009, The American Journal of Gastroenterology.

Corrigendum to "Alfapump® system vs. large volume paracentesis for refractory ascites: A multicenter randomized controlled study" [J Hepatol 67 (2017) 940-949].

R. Jalan, D. Valla, M. Stepanova, 2018, Journal of Hepatology.

P523 SAFETY AND EFFICACY OF AN AUTOMATED LOW FLOW ASCITES (ALFA) PUMP IN CIRRHOTIC PATIENTS WITH REFRACTORY ASCITES

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Brain magnetic resonance in experimental acute‐on‐chronic liver failure

J. Alonso, S. Lope-Piedrafita, J. Córdoba, 2013, Liver international : official journal of the International Association for the Study of the Liver.

Magnetic resonance imaging and spectroscopy in hepatic encephalopathy.

J. Córdoba, L. Chavarria, 2015, Journal of clinical and experimental hepatology.

Alterations in Cerebral White Matter and Neuropsychology in Patients with Cirrhosis and Falls

Y. Vives-Gilabert, B. Gómez-Anson, S. Martínez-Horta, 2015, PloS one.

Smart applications for assessing minimal hepatic encephalopathy: Novelty from the app revolution

P. Amodio, J. Córdoba, 2013, Hepatology.

Lactulose, rifaximin or branched chain amino acids for hepatic encephalopathy: what is the evidence?

G. Marchesini, H. Vilstrup, L. Gluud, 2013, Metabolic Brain Disease.

Motor‐evoked potentials in awake rats are a valid method of assessing hepatic encephalopathy and of studying its pathogenesis

J. A. Arranz, N. Chatauret, G. Bodega, 2010, Hepatology.

Ornithine phenylacetate prevents disturbances of motor-evoked potentials induced by intestinal blood in rats with portacaval anastomosis.

J. A. Arranz, J. Córdoba, Jordi Romero-Giménez, 2012, Journal of hepatology.

Definition and assessment of low-grade hepatic encephalopathy

D. Häussinger, H. Vilstrup, G. Kircheis, 2006 .

Alfapump® System versus Large Volume Paracentesis in the Treatment of Refractory Ascites; Results from a Multicenter Randomised Controlled Study (Rct)

R. Jalan, D. Valla, S. Bota, 2016 .

Gene expression profiling of brain cortex microvessels may support brain vasodilation in acute liver failure rat models

J. Córdoba, Jordi Romero-Giménez, M. Oria, 2016, Metabolic Brain Disease.

Diffusion tensor imaging supports the cytotoxic origin of brain edema in a rat model of acute liver failure.

J. Alonso, S. Lope-Piedrafita, J. Córdoba, 2010, Gastroenterology.

Matrix metalloproteinase‐9 in fulminant hepatic failure

J. Córdoba, A. Mas, L. Palenzuela, 2010, Hepatology.

Encephalopathy and liver transplantation

J. Córdoba, L. Chavarria, 2013, Metabolic Brain Disease.

Reply to: "The importance of prognostic factors in cirrhosis".

R. Esteban, J. Córdoba, M. Simón-Talero, 2014, Journal of hepatology.

L. Ferrell, J. Córdoba, T. Wright, 2000, Journal of hepatology.

Hepatic encephalopathy

A. Blei, J. Córdoba, 2001, American Journal of Gastroenterology.

[Paratesticular adenomatoid tumor: a report of nine cases].

J. Córdoba, R. A. López, A. Carranza, 2010 .

Glutamine, myo‐inositol, and brain edema in acute liver failure

J. Córdoba, 1996, Hepatology.

Magnetic resonance imaging measurement of brain edema in patients with liver disease: resolution after transplantation

À. Rovira, J. Alonso, J. Córdoba, 2002, Current opinion in neurology.

A new method for measuring motor evoked potentials in the awake rat: effects of anesthetics.

N. Chatauret, J. Córdoba, Marc Oria, 2008, Journal of neurotrauma.

Effects of Branched-Chain Amino Acids Supplementation in Patients With Cirrhosis and a Previous Episode of Hepatic Encephalopathy: A Randomized Study

E. Savarino, M. Vergara, V. Savarino, 2011, The American Journal of Gastroenterology.

Clinical Course of acute‐on‐chronic liver failure syndrome and effects on prognosis

A. de Gottardi, R. Moreau, R. Jalan, 2015, Hepatology.

New assessment of hepatic encephalopathy.

J. Córdoba, 2011, Journal of hepatology.

Motor‐evoked potentials in awake rats are a valid method of assessing hepatic encephalopathy and of studying its pathogenesis

J. A. Arranz, N. Chatauret, G. Bodega, 2010, Hepatology.

P476 SHORT-TERM (28-DAY) CLINICAL COURSE AND TRANSPLANT-FREE MORTALITY IN ACUTE ON CHRONIC LIVER FAILURE (ACLF); EVIDENCE FOR REVERSIBILITY OF ACLF (A STUDY FROM THE CANONIC DATABASE)

R. Moreau, R. Jalan, J. Trebicka, 2014 .