D. Nicholls

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C. Stanford, G. Hall, A. Chivers, 1990, British journal of industrial medicine.

Genetic screening protocol for familial hypercholesterolemia which includes splicing defects gives an improved mutation detection rate.

I. Young, C. Graham, D. Nicholls, 2005, Atherosclerosis.

Comparative physiological study of arbutamine with exercise in humans.

D. Nicholls, N. Campbell, M. Riley, 2000, Clinical science.

Effect of thoracotomy and lung resection on exercise capacity in patients with lung cancer

D. Nicholls, J. Gibbons, M. Riley, 1999, Thorax.

Cytokine profile in chronic cardiac failure

D. Nicholls, S. Maguire, A. Nugent, 1996, European journal of clinical investigation.

Management of hyperlipidaemia: guidelines of the British Hyperlipidaemia Association.

D. Betteridge, P. Dodson, P. Durrington, 1993, Postgraduate medical journal.

Laboratory facilities for investigating lipid disorders in the United Kingdom: results of the British Hyperlipidaemia Association survey.

D. Betteridge, P. Durrington, D. Nicholls, 1992, Journal of clinical pathology.

APO E Genotype and Familial Hypercholesterolaemia

I. Young, C. Graham, E. Duly, 1997, Annals of clinical biochemistry.

A novel single base deletion in the LDLR gene (211delG): Effect on serum lipid profiles and the influence of other genetic polymorphisms in the ACE, APOE and APOB genes.

I. Young, C. Graham, D. Nicholls, 1996, Atherosclerosis.

Rare apolipoprotein E variant identified in a patient with type III hyperlipidaemia.

R. Davies, I. Mcdowell, D. Nicholls, 1993, Atherosclerosis.

Management ofhyperlipidaemia: guidelines oftheBritish Hyperlipidaemia Association

P. Winocour, D. Betteridge, P. Dodson, 1993 .

Magnesium status and digoxin toxicity.

I. Young, C. Stanford, D. Nicholls, 1991, British journal of clinical pharmacology.

Abnormal vascular responses in human chronic cardiac failure are both endothelium dependent and endothelium independent

G. D. Johnston, D. Nicholls, S. Maguire, 1998, Heart.

Neuroendocrine changes in chronic cardiac failure

D. Nicholls, M. Riley, J. Elborn, 2004, Basic Research in Cardiology.

Cardiovascular effects of alinidine and propranolol alone and in combination with hydralazine in normal man.

R. Shanks, D. Harron, D. Nicholls, 1983, British journal of clinical pharmacology.

Ventilatory and heart rate responses after exercise in chronic cardiac failure.

C. Stanford, D. Nicholls, M. Riley, 1994, Clinical science.

Effect of thoracotomy and lung resection on exercise capacity in patients with lung cancer

D. Nicholls, J. Gibbons, M. Riley, 1999, Thorax.

XAMOTEROL VERSUS DIGOXIN IN HEART FAILURE

M. Rousseau, H. Pouleur, D. Nicholls, 1988, The Lancet.

Diffuse plane xanthomatosis associated with a monoclonal band displaying anti‐smooth muscle antibody activity

S. Mcmillan, D. Nicholls, M. Walsh, 1995, The British journal of dermatology.

Differential blockade of alpha-adrenoceptors by indoramin.

R. Shanks, D. Harron, D. Nicholls, 1984, British journal of clinical pharmacology.

Familial combined hyperlipidaemia: under - defined and under - diagnosed?

I. Young, A. Wierzbicki, C. Graham, 2008, Current vascular pharmacology.

Responses of atrial natriuretic peptide and brain natriuretic peptide to exercise in patients with chronic heart failure and normal control subjects

D. Nicholls, N. Campbell, G. McDowell, 1997, European journal of clinical investigation.

Aerobic work capacity in patients with chronic fatigue syndrome.

D. Mccluskey, D. Nicholls, M. Riley, 1990, BMJ.

The natriuretic peptide family

D. Nicholls, G. McDowell, C. Shaw, 1995, European journal of clinical investigation.

The effects of propranolol and digoxin on the acute vascular responses to frusemide in normal man.

G. D. Johnston, D. Nicholls, W. Leahey, 1985, British journal of clinical pharmacology.

Reproducibility of cardiopulmonary parameters during exercise in patients with chronic cardiac failure. The need for a preliminary test.

C. Stanford, D. Nicholls, J. Elborn, 1990, European heart journal.

Mechanical effects of ET-1 in cardiomyocytes isolated from normal and heart-failed rabbits

B. Silke, D. Nicholls, B. McDermott, 1996, Molecular and Cellular Biochemistry.

HDL composition and HDL antioxidant capacity in patients on regular haemodialysis.

A. Maxwell, I. Young, D. Nicholls, 1999, Atherosclerosis.

Simvastatin in severe hypercholesterolaemia: a placebo controlled trial.

I. Mcdowell, J. Shortt, D. Nicholls, 1989, British journal of clinical pharmacology.

Bradykinin infusion in chronic cardiac failure and the effects of captopril

G. D. Johnston, D. McAuley, D. Nicholls, 2001, European journal of heart failure.

Effect of flosequinan on exercise capacity and symptoms in severe heart failure.

C. Stanford, D. Nicholls, J. Elborn, 1989, British heart journal.

Mutation screening and genotype:phenotype correlation in familial hypercholesterolaemia.

I. Young, C. Graham, D. Nicholls, 1999, Atherosclerosis.

B-type natriuretic peptide as a screening test for patients undergoing echocardiography to determine left ventricular dysfunction.

D. Nicholls, R. Donnelly, C. Hughes, 2006, International journal of cardiology.

Variable patterns of atrial natriuretic peptide secretion in man

S. Hunter, D. Nicholls, N. Campbell, 1994, European journal of clinical investigation.

The effect of the neutral endopeptidase inhibitor drug, candoxatril, on circulating levels of two of the most potent vasoactive peptides.

A. Struthers, D. Nicholls, G. McDowell, 2003, British journal of clinical pharmacology.

Regulatory peptides in the plasma of patients with chronic cardiac failure at rest and during exercise.

C. Stanford, D. Nicholls, M. Riley, 1992, European heart journal.

Effect of beta-adrenoceptor blockade on atrial natriuretic peptide levels during exercise in angina pectoris.

C. Stanford, D. Nicholls, M. Riley, 1993, British journal of clinical pharmacology.

Extraction of human alpha atrial natriuretic peptide and its physiological validation.

D. Nicholls, C. Shaw, G. Onuoha, 1998, International journal of cardiology.

The effects of flosequinan on submaximal exercise in patients with chronic cardiac failure.

C. Stanford, D. Nicholls, M. Riley, 1990, British journal of clinical pharmacology.

heart failure . capacity and symptoms in severe Effect of flosequinan on exercise

C. Stanford, D. Nicholls, J. Elborn, 2005 .

The effect of pH on the buccal and sublingual absorption of captopril

J. McElnay, J. Elborn, D. Nicholls, 2004, European Journal of Clinical Pharmacology.

A double blind, placebo controlled, crossover trial of d-ribose in McArdle's disease

D. Nicholls, I. Steele, V. Patterson, 1996, Journal of the Neurological Sciences.

Variability of Nt‐proANP and C‐ANP

D. Nicholls, C. Hall, S. Maguire, 2002, European journal of clinical investigation.

A pharmacokinetic and pharmacodynamic comparison of plain and enteric-coated prednisolone tablets.

J. McElnay, C. Stanford, D. Nicholls, 1992, British journal of clinical pharmacology.

Comparison of the acute vascular effects of frusemide and bumetanide.

G. D. Johnston, D. Nicholls, M. Finch, 1986, British journal of clinical pharmacology.

Serum paraoxonase and platelet-activating factor acetylhydrolase in chronic renal failure.

A. Maxwell, I. Young, D. Nicholls, 1998, Clinical chemistry.

Stress responses after treatment of hypercholesterolaemia with simvastatin.

I. Young, C. Stanford, D. Nicholls, 1993, British journal of clinical pharmacology.

Differential Expression of Components of the Cardiomyocyte Adrenomedullin/Intermedin Receptor System following Blood Pressure Reduction in Nitric Oxide-Deficient Hypertension

Li Zhao, D. Nicholls, B. McDermott, 2006, Journal of Pharmacology and Experimental Therapeutics.

Upregulation of adrenomedullin and its receptor components during cardiomyocyte hypertrophy induced by chronic inhibition of nitric oxide synthesis in rats.

D. Nicholls, B. McDermott, Youyou Zhao, 2006, American journal of physiology. Heart and circulatory physiology.

A pharmacokinetic and pharmacodynamic evaluation of buffered sublingual captopril in patients with congestive heart failure

J. McElnay, D. Nicholls, C. Hughes, 1996, European Journal of Clinical Pharmacology.

The endopeptidase inhibitor, candoxatril, and its therapeutic potential in the treatment of chronic cardiac failure in man.

D. Nicholls, G. McDowell, Garry McDowell, 1999, Expert opinion on investigational drugs.

The Therapeutic Potential of Candoxatril, a Neutral Endopeptidase Inhibitor, in Humans

D. Nicholls, G. McDowell, 2006 .

The effects of captopril on the acute vascular responses to frusemide in man.

G. D. Johnston, D. Nicholls, W. Leahey, 1983, Clinical science.

Non-invasive measurement of cardiac output by a carbon dioxide rebreathing method at rest and during exercise.

C. Stanford, D. Nicholls, N. Campbell, 1994, European heart journal.

Distribution of Calcitonin Gene-Related Peptide, Atrial Natriuretic Peptide and Neuropeptide Y in the Rat Heart

D. Nicholls, G. Onuoha, A. Ritchie, 1998, Cardiology.

The dose-response characteristics of the acute non-diuretic peripheral vascular effects of frusemide in normal subjects.

G. D. Johnston, D. Nicholls, W. Leahey, 1984, British journal of clinical pharmacology.

The use of an exponential protocol for bicycle and treadmill exercise testing in patients with chronic cardiac failure.

H. Dargie, C. Stanford, D. Nicholls, 1992, European heart journal.

Is the secretion of atrial natriuretic peptide in man under neural control?

J. Wallwork, D. Nicholls, S. Large, 2000, European heart journal.

Comparison of transdermal nitrate and isosorbide dinitrate in chronic stable angina.

D. Nicholls, K. Moles, D. Gleadhill, 1986, British journal of clinical pharmacology.

Respiratory gas exchange and metabolic responses during exercise in McArdle's disease.

C. Stanford, D. Nicholls, M. Riley, 1993, Journal of applied physiology.

Transcutaneous oxygen tension in the leg during exercise in patients with chronic cardiac failure.

C. Stanford, D. Nicholls, M. Riley, 1990, International journal of cardiology.

THE IMPACT OF LIFELONG CARING IN IRELAND

P. W. Johnston, M. I. Halliday, D. Mccluskey, 2008 .

Calcitonin Gene-related Peptide, Neuropeptide Y and Atrial Natriuretic Peptide Distribution in Guinea Pig Heart from Paraffin wax-embedded and Formalin-cryoprotected Tissues

D. Nicholls, G. Onuoha, K. Buchanan, 1999, The Histochemical Journal.

Metabolic responses to graded exercise in chronic heart failure.

C. Stanford, D. Nicholls, M. Riley, 1993, European heart journal.

Three novel mutations in the EGF precursor homology domain of the low‐density lipoprotein receptor gene in Northern Irish patients with familial hypercholesterolemia

I. Young, C. Graham, D. Nicholls, 1995, Human mutation.

Paraoxonase polymorphisms are not associated with cardiovascular risk in renal transplant recipients.

P. McNamee, D. Middleton, A. Maxwell, 1999, Kidney international.

Indoramin-prolongation of repolarization time, a mechanism of bradycardia in man?

R. Shanks, D. Harron, D. Nicholls, 1985, British journal of clinical pharmacology.

Genetics of the lipoprotein lipase gene and hypertriglyceridaemia

I. Young, C. Graham, G. Archbold, 2003, British journal of biomedical science.

Diagnosis of heterozygous familial hypercholesterolaemia in children

C. Byrne, I. Young, C. Graham, 2008, International journal of clinical practice.

Multiplex MassARRAY spectrometry (iPLEX) produces a fast and economical test for 56 familial hypercholesterolaemia‐causing mutations

W. T. Wright, S. Humphries, S. Heggarty, 2008, Clinical genetics.

Effect of a heat and moisture retaining mask on exercise induced asthma.

C. Stanford, D. Nicholls, M. Cinnamond, 1992, BMJ.

ALTERED WARFARIN METABOLISM IN IRON-DEFICIENT PATIENT

D. Nicholls, A. Shepherd, 1978, The Lancet.

Sublingual captopril — a pharmacokinetic and pharmacodynamic evaluation

J. McElnay, J. Elborn, D. Nicholls, 2004, European Journal of Clinical Pharmacology.

The Incidence of Asymptomatic Hypothyroidism in New Referrals to a Hospital Lipid Clinic

D. Nicholls, R. Neely, M. O'Kane, 1991, Annals of clinical biochemistry.

The LDLR variant T705I does not cause the typical phenotype of familial hypercholesterolaemia.

W. T. Wright, I. Young, C. Graham, 2006, Atherosclerosis.

Acid phosphatase activity in carcinoma of the bronchus

D. Nicholls, J. S. Davies, J. Davies, 1977, Thorax.

Brain abscess presenting as an intracranial gas shadow.

D. Nicholls, J. McCann, K. C. Lee, 1987, British medical journal.

Adult coeliac disease presenting with infertility.

D. Nicholls, J. Verzin, J. McCann, 1988, Ulster medical journal.

SNPs at the APOA5 gene account for the strong association with hypertriglyceridaemia at the APOA5/A4/C3/A1 locus on chromosome 11q23 in the Northern Irish population.

W. T. Wright, I. Young, C. Patterson, 2006, Atherosclerosis.

Erythrocyte membrane fatty acid composition as a marker of dietary compliance in hyperlipidaemic subjects.

D. Nicholls, S. Maguire, I. Steele, 1995, Atherosclerosis.

The prevalence of preferential nasal breathing in adults.

C. Stanford, D. Nicholls, K. A. Ward, 1993, Respiratory medicine.

Angina in McArdle's disease.

D. Nicholls, N. Campbell, V. Patterson, 1996, Heart.

Exercise in hypertrophic cardiomyopathy is associated with sympatho-adrenal imbalance.

D. Nicholls, M. Riley, R. Donnelly, 2007, International journal of cardiology.

Acute renal failure from carbamazepine.

D. Nicholls, M. Yasin, 1972, British medical journal.

Effect of indoramin, labetalol and alinidine on sympathetic function in normal man.

R. Shanks, D. Harron, D. Nicholls, 1984, British journal of clinical pharmacology.

Cardiovascular effects of indoramin in man--a dose ranging study.

R. Shanks, D. Harron, D. Nicholls, 1983, British journal of clinical pharmacology.

Acute and chronic cardiovascular effects of indoramin and prazosin in normal man

R. Shanks, D. Harron, D. Nicholls, 1981 .

Resting energy expenditure in chronic cardiac failure.

C. Stanford, D. Nicholls, M. Riley, 1991, Clinical science.

Oxygen consumption during corridor walk testing in chronic cardiac failure.

C. Stanford, D. Nicholls, M. Riley, 1992, European heart journal.

Non-invasive measurement of cardiac output and ventricular ejection fractions in chronic cardiac failure: relationship to impaired exercise tolerance.

D. Nicholls, N. Campbell, M. Riley, 1997, Clinical science.

Neuropeptide secretion in exercise

D. Nicholls, T. Beringer, G. Onuoha, 1998, Neuropeptides.

The effect of minimal exercise on fitness in elderly women after hip surgery.

N. Murphy, D. Nicholls, A. Nugent, 1995, The Ulster medical journal.

Gas exchange responses to constant work rate exercise in chronic cardiac failure.

J. Pórszász, C. Stanford, D. Nicholls, 1994, British heart journal.

exercise in chronic cardiac failure . Gas exchange responses to constant work rate

J. Pórszász, C. Stanford, D. Nicholls, 2022 .

Substrate utilization during exercise in chronic cardiac failure.

C. Stanford, D. Nicholls, M. Riley, 1990, Clinical science.

A comparison of acipimox and nicotinic acid in type 2b hyperlipidaemia.

D. Nicholls, M. O'Kane, E. Trimble, 1991, British journal of clinical pharmacology.

Regulatory peptides in the heart and major vessels of man and mammals

E. K. Alpar, D. Nicholls, C. Shaw, 1999, Neuropeptides.

Characterisation of a cellular model of cardiomyopathy, in the rabbit, produced by chronic administration of the anthracycline, epirubicin.

B. Silke, D. Nicholls, B. McDermott, 1997, Journal of molecular and cellular cardiology.

Lung function testing in adults with preferential nasal breathing.

C. Stanford, B. Martin, D. Nicholls, 1992, Thorax.

Cardiovascular Effects of Pinacidil and Propranolol Alone and in Combination in Normal Humans

R. Shanks, D. Harron, D. Nicholls, 1986, Journal of cardiovascular pharmacology.

Acute haemodynamic effects of pinacidil in man.

R. Shanks, D. Nicholls, M. Scott, 1986, British journal of clinical pharmacology.

Comparative pharmacological and pharmacokinetic observations on propranolol (long acting formulation) and bendrofluazide administered separately and concurrently to volunteers.

R. Shanks, W. Castle, D. Harron, 1982, British journal of clinical pharmacology.

Distributions of VIP, substance P, neurokinin A and neurotensin in rat heart: an immunocytochemical study

E. K. Alpar, D. Nicholls, R. Chukwulobelu, 1999, Neuropeptides.

Irish cardiac society

G. R. Fitzgerald, C. Wilson, B. Macmahon, 1984 .

Stability of plasma concentrations of N- and C-terminal atrial natriuretic peptides at room temperature.

D. Nicholls, G. McDowell, C. Shaw, 1997, Heart.

Oxygen consumption is increased relative to work rate in patients with McArdle's disease

I. Young, D. Nicholls, M. Riley, 2004, European journal of clinical investigation.

Genetics of the lipoprotein lipase gene and hypertriglyceridaemia.

I. Young, C. Graham, G. Archbold, 2003, British journal of biomedical science.

Exercise Responses in Patients With IDDM

P. Bell, D. Nicholls, S. Vallely, 1997, Diabetes Care.

The Johns Hopkins Textbook of Dyslipidemia

I. Young, D. Nicholls, 2010 .

Comparison of labetalol and propranolol in hypertension.

C. Bulpitt, D. Nicholls, M. Stephens, 1980, British journal of clinical pharmacology.

Effect of oral and intravenous glucose on alimentary lipaemia in normal man

D. Nicholls, D. Nicholls, H. Cohen, 1985, Irish journal of medical science.

Anaerobic threshold in patients with chronic cardiac failure due to ischaemic heart disease.

C. Stanford, D. Nicholls, M. Riley, 1994, Presse medicale.

Gas exchange responses to constant work-rate exercise in patients with glycogenosis type V and VII.

K. Wasserman, H. Ong, D. Nicholls, 2004, American journal of respiratory and critical care medicine.

Lung water content is not increased in chronic cardiac failure

D. Nicholls, M. Riley, C. O'dochartaigh, 2005, Heart.

Cardiac Output during Exercise in Chronic Cardiac Failure

D. Nicholls, N. Campbell, A. Nugent, 1996 .

Which atypical pneumonia?

C. Stanford, D. Nicholls, K. Barton, 1989, Journal of Infection.

Chlordiazepoxide Metabolite Accumulation in Liver Disease

D. Nicholls, P. Auld, M. Scott, 1989, Medical toxicology and adverse drug experience.

Lipid metabolism.

I. Young, D. Nicholls, 2006, Current opinion in lipidology.