Y. Seino

发表

Serum bone alkaline phosphatase isoenzyme levels in normal children and children with growth hormone (GH) deficiency: a potential marker for bone formation and response to GH therapy.

Hiroyuki Tanaka, H. Tobiume, S. Kanzaki, 1997, The Journal of clinical endocrinology and metabolism.

Effects of discontinuation as well as intervention of cyclic therapy with etidronate on bone remodeling after cementless total hip arthroplasty.

S. Yamasaki, K. Yamaguchi, Y. Seino, 2004, Bone.

Comparison of two methods for evaluating bone marrow metastasis of neuroblastoma: Reverse transcription‐polymerase chain reaction for tyrosine hydroxylase and magnetic resonance imaging

Y. Seino, C. Takemoto, R. Nishiuchi, 2004, Pediatrics international : official journal of the Japan Pediatric Society.

Activity of renal 25-hydroxyvitamin D3-1α-hydroxylase in a case of X-linked hypophosphataemic rickets

H. Tanaka, Y. Seino, M. Ishida, 1984, European Journal of Pediatrics.

Rickets and Osteomalacia

Y. Seino, Y. Yamanaka, 2002 .

The Effects of Bone Marrow Transplantation on X‐linked Hypophosphatemic Mice

Hiroyuki Tanaka, Y. Seino, T. Miyamura, 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Bone‐forming ability of 24r,25‐dihydroxyvitamin d3 in the hypophosphatemic mouse

Toshitaka Nakamura, Hiroyuki Tanaka, H. Tanaka, 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Effect of single oral phosphate loading on vitamin D metabolites in normal subjects and in X-linked hypophosphatemic rickets.

H. Tanaka, Y. Seino, S. Nakajima, 1989, Bone and mineral.

Effects of the administration of phosphate on nuclear 1,25-dihydroxyvitamin D3 uptake by duodenal mucosal cells of Hyp mice.

H. Tanaka, Y. Seino, M. Ishida, 1988, Endocrinology.

Effect of 1α, 24(R)(OH)2D3 on calcium and phosphorus metabolism in X-linked hypophosphatemic mouse

Y. Seino, M. Ishida, H. Yabuuchi, 1984 .

Abnormal 24-hydroxylation of 25-hydroxyvitamin D in the X-linked hypophosphatemic mouse.

J. Cunningham, Y. Seino, H. Gomes, 1983, Endocrinology.

Is loss of band 7p21 really critical for manifestation of craniosynostosis in 7p-?

Y. Seino, T. Kubo, K. Narahara, 1993, American journal of medical genetics.

Craniosynostosis and hemizygosity for D7S135 caused by a de novo and apparently balanced t(6;7) translocation.

Y. Seino, S. Ninomiya, K. Narahara, 1994, American journal of medical genetics.

Assignment of SLC17A6 (alias DNPI), the gene encoding brain/pancreatic islet-type Na+-dependent inorganic phosphate cotransporter to human chromosome 11p14.3

T. Hori, H. Kasuya, Y. Seino, 2001, Cytogenetic and Genome Research.

Potential role of rhIGF-I/IGFBP-3 in maintaining skeletal mass in space.

T. Moriwake, H. Tanaka, Y. Seino, 1998, Bone.

Efficacy and safety of growth hormone treatment in Japanese children with small-for-gestational-age short stature in accordance with Japanese guidelines

Toshiaki Tanaka, Y. Seino, K. Itabashi, 2018, Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology.

Efficacy and Safety of Up to 8 Years of Long-term Growth Hormone Treatment in Short Children Born Small for Gestational Age in Japan: Analysis of the Subpopulation According to the Japanese Guideline

K. Fujieda, S. Saito, Toshiaki Tanaka, 2012, Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology.

Adult height after growth hormone treatment in Japanese children with idiopathic growth hormone deficiency: analysis from the KIGS Japan database

K. Chihara, M. Irie, K. Fujieda, 2011, Journal of Pediatric Endocrinology & Metabolism (JPEM).

Efficacy of growth hormone therapy for patients with skeletal dysplasia

Hiroyuki Tanaka, Y. Seino, N. Namba, 2003, Journal of Bone and Mineral Metabolism.

Growth Hormone Therapy in Achondroplasia

Hiroyuki Tanaka, T. Moriwake, Y. Seino, 2000, Hormone Research in Paediatrics.

Molecular defects in achondroplasia and the effects of growth hormone treatment

S. Kanzaki, T. Moriwake, H. Tanaka, 1999, Acta paediatrica (Oslo, Norway : 1992). Supplement.

Altered biochemical markers of bone turnover in humans during 120 days of bed rest.

T. Moriwake, H. Tanaka, Y. Seino, 2000, Bone.

Vitamin D is an important factor in estrogen biosynthesis of both female and male gonads.

T. Moriwake, H. Tanaka, Y. Seino, 2000, Endocrinology.

Unique karyotypes in two patients with Prader-Willi syndrome.

Y. Seino, S. Ninomiya, K. Narahara, 1992, American journal of medical genetics.

Prevalence and clinico-epidemiology of familial Graves' disease in Japan based on nationwide epidemiologic survey in 2001.

T. Akamizu, N. Amino, Yosikazu Nakamura, 2003, Endocrine journal.

Local action of exogenous growth hormone and insulin-like growth factor-I on dihydroxyvitamin D production in LLC-PK1 cells.

S. Wei, H. Tanaka, Y. Seino, 1998, European journal of endocrinology.

Bone status assessment in preterm and term infants by dual-energy X-ray absorptiometry

Hiroyuki Tanaka, Y. Seino, H. Tamai, 1998, Journal of Bone and Mineral Metabolism.

Vitamin D metabolism in osteogenesis imperfecta during calcitonin therapy.

Y. Seino, K. Yamaoka, Y. Nishi, 1984, Pediatrics.

Guidelines on the management and treatment of glucocorticoid-induced osteoporosis of the Japanese Society for Bone and Mineral Research (2004)

M. Fukunaga, K. Takaoka, Hiroyuki Tanaka, 2004, Journal of Bone and Mineral Metabolism.

Risedronate reduces postoperative bone resorption after cementless total hip arthroplasty

S. Yamasaki, K. Yamaguchi, Y. Seino, 2007, Osteoporosis International.

Favorable Impacts of Growth Hormone (GH) Replacement Therapy on Atherogenic Risks in Japanese Children with GH Deficiency

K. Chihara, M. Irie, K. Fujieda, 2012, Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology.

A controlled trial of combined therapy for newly diagnosed severe childhood IgA nephropathy. The Japanese Pediatric IgA Nephropathy Treatment Study Group.

N. Yoshikawa, Y. Seino, M. Awazu, 1999, Journal of the American Society of Nephrology : JASN.

Urinary glycylprolyl dipeptidyl aminopeptidase (GP‐DAP) in insulin‐dependent diabetic patients

S. Kanzaki, T. Moriwake, Y. Seino, 1992, Acta paediatrica.

Interim Analysis of a Phase 2 Open‐Label Trial Assessing Burosumab Efficacy and Safety in Patients With Tumor‐Induced Osteomalacia

Yutaka Takahashi, Y. Takeuchi, C. Shin, 2020, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Clinical performance of a novel chemiluminescent enzyme immunoassay for FGF23

K. Ozono, Y. Takeuchi, S. Kitanaka, 2021, Journal of Bone and Mineral Metabolism.

Favorable Impact of Growth Hormone Treatment on Cholesterol Levels in Turner Syndrome

K. Tachibana, Hiroyuki Tanaka, K. Fujieda, 2012, Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology.

Acampomelic campomelic syndrome and sex reversal associated with de novo t(12;17) translocation.

Y. Seino, S. Ninomiya, K. Narahara, 1995, American journal of medical genetics.

Cooperation of synthetic insulin-like growth factor I/somatomedin C and 1,25-dihydroxyvitamin D3 on regulation of function in clonal osteoblastic cells.

H. Tanaka, Y. Seino, H. Yabuuchi, 1989, Bone and mineral.

D, Promotes without Causing Excessive Resorption Hypophosphatemic Mice Bone Formation in

Toshitaka Nakamura, Hiroyuki Tanaka, T. Ono, 1996 .

PTH has the potential to rescue disturbed bone growth in achondroplasia.

Hiroyuki Tanaka, Y. Seino, D. Harada, 2007, Bone.

Incidence of diabetes mellitus and neoplasia in Japanese short-statured children treated with growth hormone in the Genetics and Neuroendocrinology of Short Stature International Study (GeNeSIS)

K. Chihara, Hiroyuki Tanaka, K. Ozono, 2017, Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology.

Long-Term Efficacy and Safety of Two Doses of Growth Hormone in Short Japanese Children Born Small for Gestational Age

H. Togari, K. Fujieda, Toshiaki Tanaka, 2011, Hormone Research in Paediatrics.

Insulin‐like Growth Factor‐1 Rescues the Mutated FGF Receptor 3 (G380R) Expressing ATDC5 Cells From Apoptosis Through Phosphatidylinositol 3‐Kinase and MAPK

Hiroyuki Tanaka, Y. Seino, R. Nishimura, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Molecular Basis for the Treatment of Achondroplasia

Hiroyuki Tanaka, Y. Seino, Y. Yamanaka, 2003, Hormone Research in Paediatrics.

Subject Index Vol. 60, Suppl. 3, 2003

D. Dunger, A. Vaag, R. Passier, 2003, Hormone Research in Paediatrics.

A prospective controlled study of Sairei-to in childhood IgA nephropathy with focal/minimal mesangial proliferation

N. Yoshikawa, Y. Seino, Hajime Nakamura, 1997 .

Evaluation of vitamin D-binding protein and vitamin D metabolite loss in children on continuous ambulatory peritoneal dialysis.

Y. Seino, S. Nakajima, K. Satomura, 1992, Bone and mineral.

Serum phosphate, parathyroid hormone and vitamin D metabolites in patients with chronic renal failure: effect of aluminum hydroxide administration.

Y. Seino, S. Morimoto, Y. Kumahara, 1985, Nephron.

Circulating Levels and Bone Contents of Bone γ-Carboxyglutamic Acid-Containing Protein Are Decreased in Streptozocin-Induced Diabetes: Possible Marker for Diabetic Osteopenia

H. Imura, Y. Seino, Y. Seino, 1988, Diabetes.

Effect of anticonvulsant therapy on serum 25-hydroxyvitamin D level.

Y. Seino, H. Yabuuchi, T. Shimotsuji, 1978, The Tohoku journal of experimental medicine.

Transforming growth factor beta-1 gene polymorphism and bone mineral density in Japanese adolescents.

H. Tanaka, Y. Seino, T. Hosoi, 1999, The American journal of medicine.

INSULIN AND GLUCAGON SECRETION IN HEPATIC GLYCOGENOSES

Y. Seino, H. Kodama, Y. Seino, 1979, Acta Paediatrica Scandinavica.

Multiple associated endocrine abnormalities in a patient with pseudohypoparathyroidism type 1a

Y. Seino, T. Saito, H. Yabuuchi, 1988, European Journal of Pediatrics.

Biochemical characterization of 1,25(OH)2D3 receptors in chick embryonal duodenal cytosol

L. Avioli, Y. Seino, M. Ishida, 1982, Calcified Tissue International.

1,25-Dihydroxyvitamin D radioreceptor assay using bovine mammary gland receptor and non-high performance liquid chromatographie purification

Y. Seino, Yukihiko Watanabe, Tomoko Suzuki, 1994 .

Switching from conventional therapy to burosumab injection has the potential to prevent nephrocalcinosis in patients with X-linked hypophosphatemic rickets

Y. Seino, D. Harada, H. Kashiwagi, 2021, Journal of pediatric endocrinology & metabolism : JPEM.

1,25-Dihydroxyvitamin D3 does not up-regulate vitamin D receptor messenger ribonucleic acid levels in hypophosphatemic mice.

M. Haussler, J. Pike, Y. Seino, 1992, Bone and mineral.

Decreased concentration of 1,25-dihydroxyvitamin D3 receptors in peripheral mononuclear cells of patients with X-linked hypophosphatemic rickets: effect of phosphate supplementation.

H. Tanaka, Y. Seino, S. Nakajima, 1990, Bone and mineral.

Plasma brain natriuretic peptide and the evaluation of volume overload in infants and children with congenital heart disease.

Y. Seino, S. Ohtsuki, M. Kageyama, 2003, Acta medica Okayama.

Growth hormone increases serum 1,25-dihydroxyvitamin D levels and decreases 24,25-dihydroxyvitamin D levels in children with growth hormone deficiency.

S. Wei, S. Kanzaki, T. Ono, 1997, European journal of endocrinology.

Pharmacokinetics and metabolic effects of high-dose growth hormone administration in healthy adult men.

K. Fujieda, Y. Seino, T. Tanaka,, 1999, Endocrine journal.

1,25-Dihydroxyvitamin D3 enhances the effect of refeeding on steady state preproinsulin messenger ribonucleic acid levels in rats.

Y. Seino, H. Yano, K. Yamaoka, 1990, Endocrinology.

A simple diagnostic test using GH-releasing peptide-2 in adult GH deficiency.

K. Chihara, Toshiaki Tanaka, A. Shimatsu, 2007, European journal of endocrinology.

Effect of 1,25-dihydroxyvitamin D3 on insulin secretion: direct or mediated?

H. Imura, Y. Seino, M. Ishida, 1986, Endocrinology.

Meeting report from the 1st joint meeting of the international bone and mineral society and the Japanese society for bone and mineral research

O. Johnell, R. Prince, J. Body, 2003 .

Effect of dibutyryl adenosine 3',5'-monophosphate administration on plasma concentrations of 1,25-dihydroxyvitamin D in pseudohypoparathyroidism type I.

Y. Seino, M. Ishida, H. Yabuuchi, 1981, The Journal of clinical endocrinology and metabolism.

Fibroblast growth factor 23 concentrations in healthy term infants during the early postpartum period.

Hiroyuki Tanaka, Y. Seino, T. Morishima, 2010, Bone.

Urinary pyridinoline and deoxypyridinoline in healthy children and in children with growth hormone deficiency.

H. Tanaka, Y. Seino, T. Kubo, 1995, The Journal of clinical endocrinology and metabolism.

Effects of alternate and simultaneous administrations of calcium and phosphorus on calcium metabolism in children receiving total parenteral nutrition.

Y. Seino, A. Okada, H. Yabuuchi, 1986, JPEN. Journal of parenteral and enteral nutrition.

Thrombin-antithrombin III Complex Level as a Marker of Hypercoagulable State in Insulin-dependent Diabetic Children

Toshikazu Takahashi, Y. Seino, H. Himei, 1995 .

Does growth hormone treatment prevent corticosteroid-induced osteoporosis?

H. Tanaka, Y. Seino, 1996, Bone.

Suppressive effects of human herpesvirus-6 on thrombopoietin-inducible megakaryocytic colony formation in vitro.

H. Isomura, M. Yamada, R. Ohuchi, 2000, The Journal of general virology.

Plasma active vitamin D concentration in low birthweight infants with rickets and its response to vitamin D treatment.

Y. Seino, M. Ishida, H. Yabuuchi, 1981, Archives of disease in childhood.

Treatment of hypophosphataemic vitamin D-resistant rickets with massive doses of 1 alpha-hydroxy-vitamin D3 during childhood.

Y. Seino, M. Ishida, H. Yabuuchi, 1980, Archives of disease in childhood.

Synergistic effect of 1,25-dihydroxyvitamin D3 and retinoic acid in inducing U937 cell differentiation.

Y. Seino, S. Okada, K. Yamaoka, 1992, Journal of nutritional science and vitaminology.

Effect of 1α-hydroxycholecalciferol on psoriasis vulgaris: A pilot study

Y. Kitano, Y. Seino, S. Morimoto, 1986, Calcified Tissue International.

Competitive protein binding assay for plasma 25-hydroxycholecalciferol.

Y. Seino, T. Shimotsuji, 1980, Methods in enzymology.

Serum propeptide and intact molecular osteocalcin in normal children and children with growth hormone (GH) deficiency: a potential marker of bone growth and response to GH therapy.

Hiroyuki Tanaka, S. Kanzaki, T. Moriwake, 1992, The Journal of clinical endocrinology and metabolism.

1,25-Dihydroxyvitamin D3 stimulates the secretion of insulin-like growth factor binding protein 3 (IGFBP-3) by cultured human osteosarcoma cells.

S. Kanzaki, T. Moriwake, H. Tanaka, 1992, Endocrinology.

23(S),25(R)-1,25-dihydroxyvitamin D3-26,23-lactone stimulates murine bone formation in vivo.

K. Takaoka, H. Yoshikawa, Hiroyuki Tanaka, 1990, Endocrinology.

Serum calcium regulating hormones in the perinatal period

Y. Seino, M. Ishida, S. Morimoto, 1982, Calcified Tissue International.

Hypothyroidism and hypoparathyroidism in an 11 year old boy with hemochromatosis secondary to aplastic anemia

Y. Takahashi, S. Kanzaki, Y. Seino, 1995, Acta paediatrica Japonica : Overseas edition.

Growth hormone (GH) treatment of GH-deficient children increases serum levels of insulin-like growth factors (IGFs), IGF-binding protein-3 and -5, and bone alkaline phosphatase isoenzyme.

S. Mohan, S. Kanzaki, T. Ono, 1996, Journal of Clinical Endocrinology and Metabolism.

Direct action of 1,25-dihydroxyvitamin D on bone: VDRKO bone shows excessive bone formation in normal mineral condition

Hiroyuki Tanaka, Y. Seino, 2004, The Journal of Steroid Biochemistry and Molecular Biology.

Relationship of interleukin‐8 and colony‐stimulating factors to neutrophil migration in aseptic meningitis

Y. Seino, M. Oda, T. Horiuchi, 1996, Acta paediatrica.

Final adult height in long-term growth hormone-treated achondroplasia patients

Y. Seino, N. Namba, D. Harada, 2017, European Journal of Pediatrics.

Onset of puberty and near adult height in short children born small for gestational age and treated with GH: Interim analysis of up to 10 years of treatment in Japan

Toshiaki Tanaka, Y. Seino, S. Yokoya, 2015, Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology.

Onset of puberty and near adult height in short children born small for gestational age and treated with GH: Interim analysis of up to 10 years of treatment in Japan

Toshiaki Tanaka, Y. Seino, S. Yokoya, 2015, Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology.

Monthly intravenous alendronate treatment can maintain bone strength in osteogenesis imperfecta patients following cyclical pamidronate treatment

Hiroyuki Yamada, Hiroyuki Tanaka, Y. Seino, 2020, Journal of pediatric endocrinology & metabolism : JPEM.

Effect of growth hormone on fatty liver in panhypopituitarism

S. Kanzaki, Y. Seino, T. Kubo, 1997, Archives of disease in childhood.

Glomerular TGF + , expression in children syndrome with nephrotic

M. Yasui, Hiroyuki Tanaka, Yasushi Kobayashi, 2006 .

A986S polymorphism of calcium-sensing receptor

Hiroyuki Tanaka, Y. Seino, H. Kanazawa, 1999, The Lancet.

Safety and Efficacy of Burosumab in Pediatric Patients With X-Linked Hypophosphatemia: A Phase 3/4 Open-Label Trial

K. Ozono, T. Kubota, Y. Seino, 2022, Journal of the Endocrine Society.

Vitamin D in bone formation

H. Tanaka, Y. Seino, M. Shima, 2005, Osteoporosis International.

1,25-Dihydroxyvitamin D3 [1,25-(OH)2D3] increases insulin-like growth factor I (IGF-I) receptors in clonal osteoblastic cells. Study on interaction of IGF-I and 1,25-(OH)2D3.

Y. Seino, S. Nakajima, K. Yamaoka, 1990, Endocrinology.

Blunted effect of parathyroid hormone on adenosine 3′,5′-cyclic monophosphate production is derived from ATP depletion in proximal convoluted tubules of hypophosphatemic mice

Y. Seino, K. Yamaoka, T. Yamamoto, 2000, Clinical and Experimental Nephrology.

Medical management and complications of X‐linked hypophosphatemic vitamin D resistant rickets

T. Ono, Y. Seino, 1997, Acta paediatrica Japonica : Overseas edition.

Vaccination with multiple antigen peptide as rejection antigen peptide in murine leukemia.

Y. Seino, T. Ono, E. Nakayama, 1998, Cancer research.

First‐in‐Asian Phase I Study of the Anti‐Fibroblast Growth Factor 23 Monoclonal Antibody, Burosumab: Safety and Pharmacodynamics in Adults With X‐linked Hypophosphatemia

H. Cheong, Hiroyuki Tanaka, K. Ozono, 2018, JBMR plus.

Use of oral calcium loading to characterize the hypercalciuria of young insulin-dependent diabetics.

N. White, L. Avioli, J. Santiago, 1983, The Journal of clinical endocrinology and metabolism.

The Duodenal lμ,25-Dihydroxyvitamin D3 Receptor in Rats with Experimentally Induced Diabetes*

L. Avioli, S. Birge, Y. Seino, 1983 .

A specific competitive protein binding assay for serum 24,25-dihydroxyvitamin D in normal children and patients with nephrotic syndrome.

Y. Seino, M. Ishida, H. Yabuuchi, 1980, Clinica chimica acta; international journal of clinical chemistry.

Decreased 1,25-dihydroxyvitamin D3 receptor density is associated with a more severe form of parathyroid hyperplasia in chronic uremic patients.

K. Kurokawa, H. Tanaka, Y. Seino, 1993, The Journal of clinical investigation.

Hemodynamic characteristics of echocardiographic findings in hypertensive patients with negative U waves and effect of an antihypertensive drug, tripamide.

H. Kishida, T. Tanaka, Y. Seino, 1987, Japanese heart journal.

Serum levels of carboxyterminal propeptide of type I procollagen and pyridinoline crosslinked telopeptide of type I collagen in normal children and children with growth hormone (GH) deficiency during GH therapy.

S. Kanzaki, H. Tanaka, Y. Seino, 1995, Bone.

Impaired pyridinoline cross-link formation in patients with osteogenesis imperfecta

Hiroyuki Tanaka, Y. Seino, T. Morishima, 2008, Journal of Bone and Mineral Metabolism.

No enzyme activity of 25-hydroxyvitamin D3 1alpha-hydroxylase gene product in pseudovitamin D deficiency rickets, including that with mild clinical manifestation.

S. Kato, A. Murayama, K. Inouye, 1999, The Journal of clinical endocrinology and metabolism.

Bone Mineral Status in Turner Syndrome

Hiroyuki Tanaka, S. Kanzaki, T. Ono, 1995 .

A multiple assay for vitamin D metabolites without high-performance liquid chromatography.

S. Wei, H. Tanaka, Y. Seino, 1994, Analytical biochemistry.

THE PLASMA LEVELS OF 25‐HYDROXYVITAMIN D IN PATIENTS WITH VARIOUS LIVER DISEASES AND THE RESPONSE OF 25‐HYDROXYVITAMIN D TO VITAMIN D TREATMENT

Y. Seino, H. Yabuuchi, T. Shimotsuji, 1978, Acta paediatrica Scandinavica.

Renal 25-hydroxyvitamin D3-1-hydroxylase in patients with renal disease.

H. DeLuca, Y. Seino, M. Ishida, 1988, Kidney international.

1,25(OH)2D and 24,25(OH)2D production in the developing kidney

Y. Seino, M. Ishida, M. Shima, 2004, Pediatric Nephrology.

Increased circulating levels of γ-carboxyglutamic acid-containing protein and decreased bone mass in children on anticonvulsant therapy

H. Imura, Hiroyuki Tanaka, Y. Seino, 1989, Calcified Tissue International.

Increased Circulating Levels of ~/-Carboxyglutamic Protein and Decreased Bone Mass in Children on Anticonvulsant Therapy

H. Imura, Hiroyuki Tanaka, M. Nozawa, 1989 .

Osteoclastogenesis Inhibitory Factor/Osteoprotegerin Reduced Bone Loss Induced by Mechanical Unloading

S. Mochizuki, H. Tanaka, Y. Seino, 2004, Calcified Tissue International.

Effect of age on duodenal 1,25-dihydroxyvitamin D-3 receptors in Wistar rats.

C. Liang, B. Sacktor, Y. Seino, 1990, Biochimica et biophysica acta.

Expression of parathyroid hormone-related peptide messenger ribonucleic acid in developing kidney.

H. Tanaka, Y. Seino, M. Kobayashi, 1999, Kidney international.

[The effect of purification procedures on the determination of serum level of 1,25-dihydroxyvitamin D].

H. Tanaka, Y. Seino, M. Ishida, 1988, Nihon Naibunpi Gakkai zasshi.

Expression of PTHrP mRNA in kidney.

Y. Seino, Hiroyuki Tanaka, K. Aya, 1997 .

Serum free insulin-like growth factor I (IGF-I), total IGF-I, and IGF-binding protein-3 concentrations in normal children and children with growth hormone deficiency.

S. Kanzaki, Y. Seino, Y. Yamanaka, 1999, The Journal of clinical endocrinology and metabolism.

The Effects of Anticonvulsants on Liver and Bone Metabolism

Y. Seino, S. Okada, H. Yabuuchi, 1977 .

PLASMA CLEARANCE FOR HIGH DOSES OF EXOGENOUS 1,25-DIHYDROXY[23,24(n)- 3 H]CHOLECALCIFEROL IN X-LINKED HYPOPHOSPHATEMIC MICE

Y. Seino, M. Ishida, H. Yabuuchi, 1982 .

PTHrP Rescues ATDC5 Cells From Apoptosis Induced by FGF Receptor 3 Mutation

Hiroyuki Tanaka, Y. Seino, R. Nishimura, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The role of tissue-fixed macrophages in apoptosis in the developing kidney.

M. Yasui, H. Tanaka, Y. Seino, 1997, Nephron.

A Case of Vitamin D Dependency Type I

K. Ozono, Y. Seino, S. Nakajima, 1992 .

Effect of Sex Hormones on Bone Mineral Density in Children

Hiroyuki Tanaka, S. Kanzaki, T. Ono, 1996 .

EFFECT OF PORCINE CALCITONIN THERAPY ON VITAMIN D METABOLISM AND CLINICAL RESPONSE IN A PATIENT WITH OSTEOGENESIS IMPERFECTA

Y. Seino, M. Ishida, K. Yamaoka, 1983, Acta paediatrica Scandinavica.

1, 25-Dihydroxyvitamin D3 receptor density is decreased in an advanced type of parathyroid hyperplasia due to chronic renal failure

K. Kurokawa, Y. Seino, M. Fukagawa, 1994 .

Suppressive effects of human herpesvirus 6 on in vitro colony formation of hematopoietic progenitor cells

H. Isomura, Hiroyuki Tanaka, M. Yamada, 1997, Journal of medical virology.

Disassociation of the macrophage-maturational effects of vitamin D from respiratory burst priming.

K. Hruska, S. Teitelbaum, J. Malone, 1991, The Journal of biological chemistry.

[Serum levels of intact molecular osteocalcin in children with growth hormone (GH) deficiency during GH therapy: an early predictor of GH therapy].

S. Kanzaki, Y. Seino, T. Kubo, 1994, Nihon Naibunpi Gakkai zasshi.

The circadian rhythms of blood ionized calcium in humans.

Y. Seino, M. Ishida, K. Satomura, 1983, Scandinavian journal of clinical and laboratory investigation. Supplementum.

Nephrin is an important component of the barrier system in the testis.

H. Tanaka, Y. Seino, L. Liu, 2001, Acta medica Okayama.

Treatment of renal osteodystrophy in children with 1αOHD3 and 24, 25(OH)2D3

Hiroyuki Tanaka, Y. Seino, M. Ishida, 1988, Journal of Bone and Mineral Metabolism.

A missense mutation in the nephrin gene impairs membrane targeting.

Hiroyuki Tanaka, Y. Sado, Y. Seino, 2002, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Mutations in type I collagen genes in Japanese osteogenesis imperfecta patients

Hiroyuki Tanaka, Y. Seino, T. Morishima, 2007, Pediatrics international : official journal of the Japan Pediatric Society.

Gardner syndrome in a boy with interstitial deletion of the long arm of chromosome 5.

Y. Seino, S. Ohtsuki, K. Narahara, 1991, American journal of medical genetics.

Cryptic pericentric inversion of chromosome 17 detected by fluorescence in situ hybridization study in familial Miller-Dieker syndrome.

Y. Seino, T. Miyawaki, K. Narahara, 1997, American journal of medical genetics.

Novel mutation in the nephrin gene of a Japanese patient with congenital nephrotic syndrome of the Finnish type.

Hiroyuki Tanaka, H. Tanaka, Y. Seino, 2000, Kidney international.

Malignant osteopetrosis treated with high doses of 1α-hydroxyvitamin D3 and interferon gamma

Hiroyuki Tanaka, S. Kanzaki, T. Moriwake, 1993 .

Effect of Sex Hormones on Bone Mineral Density in Children:Is the Increase in Bone Mineral Density during Puberty only due to Rapid Height Gain?

Hiroyuki Tanaka, S. Kanzaki, T. Ono, 1996 .

Changes in calcium homeostasis in acromegaly treated by pituitary adenomectomy.

Y. Seino, S. Morimoto, T. Uozumi, 1985, The Journal of clinical endocrinology and metabolism.

Identification of the cell type origin of odontoma‐like cell masses in microphthalmic (mi/mi) mice by in situ hybridization

Y. Kitamura, Hiroyuki Tanaka, Y. Seino, 1996, Pathology international.

Frequencies of spontaneous breast development and spontaneous menarche in Turner syndrome in Japan

K. Tachibana, Hiroyuki Tanaka, K. Ozono, 2015, Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology.

Serum levels of vitamin D metabolites in children receiving total parenteral nutrition.

Y. Seino, H. Yabuuchi, K. Yamaoka, 1986, JPEN. Journal of parenteral and enteral nutrition.

A case of acute lymphoblastic leukemia accompanied with the production of parathyroid hormone-related protein.

H. Tanaka, Y. Seino, M. Oda, 1995, Mineral and electrolyte metabolism.

45,X/46,X,idic(Yq) mosaicism: clinical, cytogenetic, and molecular studies in four individuals.

Y. Seino, K. Narahara, Y. Yokoyama, 1998, American journal of medical genetics.

Japanese growth prediction model for prepubertal children with growth hormone deficiency

K. Chihara, Hiroyuki Tanaka, Toshiaki Tanaka, 2012, Journal of pediatric endocrinology & metabolism : JPEM.

Activated Proliferation of B-Cell Lymphomas/Leukemias with the SHP1 Gene Silencing by Aberrant CpG Methylation

K. Hayashi, T. Yoshino, T. Akagi, 2003, Laboratory Investigation.

Assignment of human porphobilinogen deaminase to 11q24.1----q24.2 by in situ hybridization and gene dosage studies.

Y. Seino, K. Narahara, Y. Yokoyama, 1991, Cytogenetics and cell genetics.

Growth Hormone and Bone

Y. Seino, D. Harada, 2014 .

Rapid screening method to detect mutations in CYP21, the gene for 21-hydroxylase.

Y. Seino, S. Ninomiya, K. Narahara, 2000, American journal of medical genetics.

Effect of growth hormone therapy in children with achondroplasia: growth pattern, hypothalamic-pituitary function, and genotype.

S. Kanzaki, T. Ono, H. Tanaka, 1998, European journal of endocrinology.

Sustained phosphorylation of mutated FGFR3 is a crucial feature of genetic dwarfism and induces apoptosis in the ATDC5 chondrogenic cell line via PLCgamma-activated STAT1.

Hiroyuki Tanaka, Y. Seino, T. Morishima, 2007, Bone.

Prevalence of idiopathic hypoparathyroidism and pseudohypoparathyroidism in Japan.

A. Tamakoshi, T. Kawamura, Toshio Matsumoto, 2000, Journal of epidemiology.

Maternal origin of a unique extra chromosome, der(9)(pter-->q13::q13-->q12:) in a girl with typical trisomy 9p syndrome.

Y. Seino, S. Ninomiya, K. Narahara, 2001, American journal of medical genetics.

Tissue-specific mosaicism for trisomy 21 and congenital heart disease.

Y. Seino, K. Narahara, Y. Yokoyama, 1992, The Journal of pediatrics.

Hiroyuki Tanaka, Y. Seino, D. Harada, 2009, Journal of Bone and Mineral Metabolism.

Growth Hormone Therapy in Achondroplasia (ACH)

Hiroyuki Tanaka, Y. Seino, H. Tokumaru, 1997 .

Achondroplasia: Effect of Growth Hormone in 40 Patients

Hiroyuki Tanaka, S. Kanzaki, Y. Seino, 1994 .

Achondroplasia associated with pelvic lipomatosis

Hiroyuki Tanaka, S. Kanzaki, T. Ono, 1999, The Lancet.

1,25-Dihydroxyvitamin D3 stimulates the secretion of insulin-like growth factor binding protein 3 (IGFBP-3) by cultured human osteosarcoma cells.

S. Kanzaki, T. Moriwake, H. Tanaka, 1992, Endocrinology.

Analysis of linear growth in survivors of childhood acute lymphoblastic leukemia

Hiroyuki Tanaka, T. Moriwake, Y. Seino, 2003, Journal of Bone and Mineral Metabolism.

Clonal analysis by polymerase chain reaction of B‐cell lymphoma with late relapse: A report of five cases

T. Yoshino, T. Akagi, Y. Seino, 1996, Cancer.

An ultrasensitive assay revealed age‐related changes in serum oestradiol at low concentrations in both sexes from infancy to puberty

Hiroyuki Tanaka, Yoshiki Seino, Hiroyuki Tanaka, 2001, Clinical endocrinology.

Vitamin D metabolism in hypophosphatemic vitamin D-resistant rickets.

Y. Seino, M. Ishida, H. Yabuuchi, 1980, Contributions to nephrology.

Intranasal absorption of salmon calcitonin

Hiroyuki Tanaka, Y. Seino, M. Ishida, 1987, Calcified Tissue International.

Autosomal dominant congenital cataract and microphthalmia associated with a familial t(2;16) translocation

Y. Seino, S. Ninomiya, K. Narahara, 1992, Human Genetics.

[Neurologic diseases of enterovirus infections: polioviruses, coxsackieviruses, echoviruses, and enteroviruses type 68-72].

Y. Seino, M. Oda, A. Manki, 1997, Nihon rinsho. Japanese journal of clinical medicine.

Two novel missense mutations in calcium-sensing receptor gene associated with neonatal severe hyperparathyroidism.

H. Tanaka, Y. Seino, M. Kobayashi, 1997, The Journal of clinical endocrinology and metabolism.

New familial nephropathy involving glomerular and tubular basement membranes

M. Yasui, Hiroyuki Tanaka, Y. Seino, 1994, Pediatric Nephrology.

Reproductive risk in mating between two translocation carriers: case report and review of the literature.

Y. Hiramatsu, Y. Seino, S. Ninomiya, 1993, American journal of medical genetics.

Growth Hormone (GH) Treatment in Achondroplasia

S. Kanzaki, T. Moriwake, H. Tanaka, 1993, The Journal of pediatric endocrinology.

The effect of calcium-sensing receptor gene polymorphisms on serum calcium levels: a familial hypocalciuric hypercalcemia family without mutation in the calcium-sensing receptor gene.

H. Tanaka, Y. Seino, M. Kobayashi, 2000, Endocrine journal.

Pseudohypoparathyroidism type II and anticonvulsant rickets

I. Matsuda, N. Matsuura, Y. Seino, 2004, European Journal of Pediatrics.

Growth hormone deficiency and empty sella syndrome in a boy with dup(X) (q13.3----q21.2).

S. Kanzaki, T. Moriwake, Y. Seino, 1992, American journal of medical genetics.

Expression of TGF‐α, EGF and their common receptor in human fetal kidney

M. Yasui, Hiroyuki Tanaka, Y. Seino, 1997 .

Isolation of a testis-specific cDNA on chromosome 17q from a region adjacent to the breakpoint of t(12;17) observed in a patient with acampomelic campomelic dysplasia and sex reversal.

Y. Nakamura, Y. Seino, S. Ninomiya, 1996, Human molecular genetics.

[A prospective controlled study of sairei-to in childhood IgA nephropathy with focal/minimal mesangial proliferation. Japanese Pediatric IgA Nephropathy Treatment Study Group].

Y. Seino, M. Awazu, M. Honda, 1997, Nihon Jinzo Gakkai shi.

The Usefulness of Ultrasensitive Assay for Estradiol in Both Sexes During Childhood

Hiroyuki Tanaka, S. Kanzaki, T. Moriwake, 2000 .

Recent progress in diagnosis and treatment of osteogenesis imperfecta

T. Moriwake, Y. Seino, 1997, Acta paediatrica Japonica : Overseas edition.

A case of autosomal dominant osteopetrosis type II with a novel TCIRG1 gene mutation

Kanako Tachikawa, T. Michigami, Y. Seino, 2013, Journal of pediatric endocrinology & metabolism : JPEM.

Evaluation of Quality of Life in Children with GH Deficiency and Idiopathic Short Stature Using the Child Behavior Checklist

K. Chihara, K. Tachibana, K. Fujieda, 2009, Clinical Pediatric Endocrinology.

A study of bone mineral density and physical growth in very low birth-weight infants after their discharge from hospital

H. Shintaku, Y. Seino, H. Tamai, 2002, Journal of Bone and Mineral Metabolism.

Clinical evaluation of recombinant human growth hormone in Noonan syndrome.

Hiroyuki Tanaka, Toshiaki Tanaka, A. Tanae, 2004, Endocrine journal.

Effect of Growth Hormone Treatment on Quality of Life in Japanese Children with Growth Hormone Deficiency: An Analysis from a Prospective Observational Study

K. Chihara, Hiroyuki Tanaka, K. Ozono, 2014, Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology.

An observational study of the effectiveness and safety of growth hormone (Humatrope(®)) treatment in Japanese children with growth hormone deficiency or Turner syndrome.

K. Chihara, Hiroyuki Tanaka, K. Fujieda, 2013, Endocrine journal.

Low-dose growth hormone treatment (0.175 mg/kg/week) for short stature in patients with Turner Syndrome: data from KIGS Japan.

K. Chihara, M. Irie, K. Fujieda, 2006, Endocrine journal.

Thyroid-stimulating antibody in a patient with euthyroid Graves' disease.

S. Kanzaki, T. Moriwake, Y. Seino, 2000, Endocrine journal.

[Standard versus long-term prednisolone with sairei-to for initial therapy in childhood steroid-responsive nephrotic syndrome: a prospective controlled study].

I. Matsuda, Y. Seino, K. Iijima, 1998, Nihon Jinzo Gakkai shi.

Circulating 1 alpha,25-dihydroxyvitamin D levels after a single dose of 1 alpha,25-dihydroxyvitamin D3 or 1 alpha-hydroxyvitamin D3 in normal men.

H. Tanaka, Y. Seino, H. Yabuuchi, 1987, Bone and mineral.

Terminal 22q deletion associated with a partial deficiency of arylsulphatase A.

Y. Takahashi, Y. Seino, S. Ninomiya, 1992, Journal of medical genetics.

Differential diagnosis of hypoparathyroid disorders during childhood

Y. Seino, M. Ishida, K. Nishimura, 2006, Calcified Tissue International.

Secretion of osteocalcin and its propeptide from human osteoblastic cells: Dissociation of the secretory patterns of osteocalcin and its propeptide

S. Kanzaki, Y. Seino, K. Hosoda, 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

LEVELS OF VITAMIN D‐METABOLITES IN A CASE OF ACRO‐OSTEOLYSIS SYNDROME

Y. Seino, M. Kobayashi, K. Yamaoka, 1983, Acta paediatrica Scandinavica.

Anticonvulsant-induced rickets associated with renal tubular acidosis and normal level of serum 1,25-dihydroxyvitamin D.

I. Matsuda, Y. Seino, T. Ishitsu, 1981, American journal of diseases of children.

Abnormal relationship between serum phosphate concentration and renal 25-hydroxycholecalciferol-1-alpha-hydroxylase activity in X-linked hypophosphatemic mice.

M. Haussler, Y. Seino, H. Yabuuchi, 1986, Mineral and electrolyte metabolism.

24R,25-dihydroxyvitamin D3 promotes bone formation without causing excessive resorption in hypophosphatemic mice.

Hiroyuki Tanaka, T. Ono, H. Tanaka, 1996, Endocrinology.

Circulating vitamin D metabolite levels in hypophosphatasia.

M. Whyte, Y. Seino, Michael P. Whyte, 1982, The Journal of clinical endocrinology and metabolism.

The Role of Tissue-Fixed Macrophages in Apoptosis in the Developing Kidney

M. Yasui, Hiroyuki Tanaka, Y. Seino, 1997 .

A case of perinatal hypophosphatasia with a novel mutation in the ALPL gene: clinical course and review of the literature

T. Akiyama, T. Michigami, Y. Seino, 2018, Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology.

Cytokines and growth factors which regulate bone cell function.

Y. Seino, 1994, Acta Astronautica.

1,25-Dihydroxyvitamin D radioreceptor assay using bovine mammary gland receptor and non-high performance liquid chromatographic purification.

Y. Seino, T. Suzuki, Y. Watanabe, 1994, Clinica chimica acta; international journal of clinical chemistry.

The effects of recombinant human insulin‐like growth factor (rhIGF)‐1 and rhIGF‐1/IGF binding protein‐3 administration on rat osteopenia induced by ovariectomy with concomitant bilateral sciatic neurectomy

Toshitaka Nakamura, Hiroyuki Tanaka, Y. Seino, 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Development of Novel Therapy for Achondroplasia: Use of Parathyroid Hormone

Hiroyuki Tanaka, Y. Seino, D. Harada, 2005 .

Rejection of parental meth-a tumor on concomitant inoculation of meth-a cells infected retrovirally with the interferon-gamma gene into (balb/cxc57bl/6)f-1 mice.

M. Hikida, Y. Watanabe, Y. Seino, 1995, International journal of oncology.

The Clinical Usefulness of Liquid Human Growth Hormone (hGH) (Norditropin® SimpleXxTM) in the Treatment of GH Deficiency

T. Moriwake, Y. Seino, K. Iyoda, 1999, Hormone Research in Paediatrics.

Normal serum 1,25-dihydroxyvitamin D in patients with medullary carcinoma of the thyroid.

A. Miyauchi, Y. Seino, M. Ishida, 1982, The Journal of clinical endocrinology and metabolism.

Persistence of TEL‐AML1 transcript in acute lymphoblastic leukemia in long‐term remission

Y. Seino, R. Nishiuchi, C. Endo, 2003, Pediatrics international : official journal of the Japan Pediatric Society.

Vitamin D metabolites in human milk from mothers of preterm and full-term infants

Y. Seino, S. Okada, M. Zheng, 1990, Journal of Bone and Mineral Metabolism.

Vitamin D metabolism in biliary atresia: intestinal absorptions of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3.

H. Tanaka, Y. Seino, H. Yabuuchi, 1988, Journal of pediatric gastroenterology and nutrition.

High‐dose growth hormone (GH) treatment in prepubertal GH‐deficient children

K. Fujieda, N. Iwatani, Y. Seino, 1999, Acta paediatrica (Oslo, Norway : 1992). Supplement.

Self-Administration of Burosumab in Children and Adults with X-Linked Hypophosphataemia in Two Open-Label, Single-Arm Clinical Studies

K. Ozono, Y. Takeuchi, Y. Imanishi, 2023, Advances in Therapy.

Glomerular TGF‐β1 expression in children with nephrotic syndrome

M. Yasui, Hiroyuki Tanaka, Yasushi Kobayashi, 1996 .

Plasma 1,25-dihydroxyvitamin D concentrations in cords, newborns, infants, and children

Y. Seino, M. Ishida, H. Yabuuchi, 2006, Calcified Tissue International.

Secondary hyperparathyroidism with 1,25-dihydroxyvitamin D deficiency and pseudohypoparathyroidism in childhood: Relationship between plasma 1,25-dihydroxyvitamin D and parathyroid hormone levels and urinary cyclic AMP response to exogenous PTH

M. Fukase, T. Fujita, Y. Seino, 1981, European Journal of Pediatrics.

GH Treatment in a Patient with Partial GH Insensitivity Syndrome

S. Kanzaki, T. Moriwake, Y. Seino, 2000 .

Interleukin-1 beta and interleukin-1 receptor antagonist levels in cerebrospinal fluid of aseptic meningitis patients.

Y. Seino, M. Oda, T. Yokoyama, 1998, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Cleidocranial dysplasia associated with a t(6;18)(p12;q24) translocation.

Y. Seino, K. Narahara, Y. Yokoyama, 1995, American journal of medical genetics.

Relations of plasma 25-hydroxyvitamin D levels in mothers, cord blood and newborn infants, and postnatal changes in plasma 25-hydroxy-vitamin D levels.

Y. Seino, M. Ishida, H. Yabuuchi, 1979, Journal of nutritional science and vitaminology.

Two novel mutations of SURF1 in Leigh syndrome with cytochrome c oxidase deficiency

Y. Seino, S. Ninomiya, Y. Yokoyama, 1999, Human Genetics.

Purification of an 80 kDa Ca2+-dependent actin-modulating protein, which severs actin filaments, from bovine adrenal medulla.

K. Sobue, Y. Seino, H. Yabuuchi, 1987, Journal of Biochemistry (Tokyo).

Phosphate administration enhances the action of 1,25(OH)2D3 in familial hypophosphatemic vitamin D resistant rickets.

H. Tanaka, Y. Seino, K. Yamaoka, 1992, Journal of nutritional science and vitaminology.

Abnormal bone formation induced by implantation of osteosarcoma-derived bone-inducing substance in the X-linked hypophosphatemic mouse.

K. Takaoka, H. Yoshikawa, K. Ono, 1985, Bone.