Syann Lee

发表

FGF21 regulates metabolism and circadian behavior by acting on the nervous system

S. Kliewer, J. Takahashi, A. Bookout, 2013, Nature Medicine.

Melanocortin regulation of histaminergic neurons via perifornical lateral hypothalamic melanocortin 4 receptors

J. Elmquist, J. Zigman, Charlotte E. Lee, 2020, Molecular metabolism.

Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance

J. Elmquist, C. Buchanan, M. Brimble, 2017, Molecular metabolism.

Melanocortin‐4 receptor expression in different classes of spinal and vagal primary afferent neurons in the mouse

J. Elmquist, Charlotte E. Lee, Syann Lee, 2012, The Journal of comparative neurology.

Melanocortin‐4 receptor expression in a vago‐vagal circuitry involved in postprandial functions

J. Friedman, J. Elmquist, Charlotte E. Lee, 2010, The Journal of comparative neurology.

Expression of the diabetes‐associated gene TCF7L2 in adult mouse brain

J. Elmquist, C. Elias, Charlotte E. Lee, 2009, The Journal of comparative neurology.

Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis.

J. Elmquist, Yongsheng Chang, M. Fukuda, 2014, Cell metabolism.

The Ventral Premammillary Nucleus Links Fasting-Induced Changes in Leptin Levels and Coordinated Luteinizing Hormone Secretion

N. Canteras, C. Elias, Charlotte E. Lee, 2009, The Journal of Neuroscience.

Loss of the liver X receptor LXRα/β in peripheral sensory neurons modifies energy expenditure

Yuan Zhang, A. Bookout, D. Mangelsdorf, 2015, eLife.

Hepatocyte Toll-like Receptor 4 Regulates Obesity-Induced Inflammation and Insulin Resistance

J. Elmquist, M. Fukuda, P. Scherer, 2014, Nature Communications.

PPARγ mRNA in the adult mouse hypothalamus: distribution and regulation in response to dietary challenges

A. Bookout, Hua Wu, Syann Lee, 2015, Front. Neuroanat..

Hepatocyte toll-like receptor 4 deficiency protects against alcohol-induced fatty liver disease

Newaz I. Ahmed, J. Elmquist, P. Scherer, 2018, Molecular metabolism.

TLR 2 / 4-dependent neonatal toxicity Maternal western diet causes inflammatory milk and Material Supplemental

A. Saghatelian, Y. Wan, Yang Du, 2012 .

Maternal western diet causes inflammatory milk and TLR2/4-dependent neonatal toxicity.

A. Saghatelian, Y. Wan, Yang Du, 2012, Genes & development.

Melanocortin 4 receptors in autonomic neurons regulate thermogenesis and glycemia

Linh Vong, B. Lowell, D. Olson, 2014, Nature Neuroscience.

Nutritional conditions regulate transcriptional activity of SF-1 by controlling sumoylation and ubiquitination

J. Elmquist, G. Hammer, Syann Lee, 2016, Scientific Reports.

Essential role for the Prader-Willi syndrome protein necdin in axonal outgrowth.

R. Wevrick, B. Karten, Syann Lee, 2005, Human molecular genetics.

Serotonergic Control of Metabolic Homeostasis

J. Elmquist, C. Lord, Syann Lee, 2017, Front. Cell. Neurosci..

TLR4 Signaling Selectively and Directly Promotes CGRP Release from Vagal Afferents in the Mouse

J. Elmquist, M. Burton, Syann Lee, 2020, eNeuro.

The microbiota coordinates diurnal rhythms in innate immunity with the circadian clock

J. Takahashi, John F. Brooks, L. Hooper, 2021, Cell.

The atypical antipsychotic olanzapine causes weight gain by targeting serotonin receptor 2C.

Newaz I. Ahmed, J. Elmquist, C. Lord, 2017, The Journal of clinical investigation.

Leptin and insulin engage specific PI3K subunits in hypothalamic SF1 neurons

J. Elmquist, Youjin Oh, K. Williams, 2016, Molecular metabolism.

Neuronal E93 regulates metabolic homeostasis

J. Elmquist, A. Rothenfluh, Young-Jai You, 2022, bioRxiv.

CB1Rs in VMH Neurons Regulate Glucose Homeostasis but not Body Weight.

Newaz I. Ahmed, J. Elmquist, J. Horton, 2021, American journal of physiology. Endocrinology and metabolism.

Lipopolysaccharide induces filtrate leakage from renal tubular lumina into the interstitial space via a proximal tubular Toll-like receptor 4-dependent pathway and limits sensitivity to fluid therapy in mice.

A. Nishiyama, H. Wiig, M. Yanagita, 2019, Kidney international.

P110β in the ventromedial hypothalamus regulates glucose and energy metabolism

C. Elias, Charlotte E. Lee, D. Shin, 2019, Experimental & Molecular Medicine.

Leptin and brain–adipose crosstalks

Alexandre Caron, Joel K. Elmquist, J. Elmquist, 2018, Nature Reviews Neuroscience.

Adipocyte Gs but not Gi signaling regulates whole-body glucose homeostasis

J. Elmquist, P. Scherer, Charlotte E. Lee, 2019, Molecular metabolism.

Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons.

J. Friedman, R. Coppari, J. Elmquist, 2011, The Journal of clinical investigation.

Dnmt3a in Sim1 Neurons Is Necessary for Normal Energy Homeostasis

Guoping Fan, J. Elmquist, G. Fan, 2014, The Journal of Neuroscience.

POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels

Newaz I. Ahmed, J. Elmquist, Charlotte E. Lee, 2018, eLife.

Brain SIRT1: Anatomical Distribution and Regulation by Energy Availability

A. Bookout, R. Coppari, J. Elmquist, 2008, The Journal of Neuroscience.

Absence of Ndn, Encoding the Prader-Willi Syndrome-Deleted Gene necdin, Results in Congenital Deficiency of Central Respiratory Drive in Neonatal Mice

J. Greer, C. Stewart, R. Wevrick, 2003, The Journal of Neuroscience.

SF-1 expression in the hypothalamus is required for beneficial metabolic effects of exercise

Newaz I. Ahmed, J. Elmquist, Joseph A. Hill, 2016, eLife.

P110β in the ventromedial hypothalamus regulates glucose and energy metabolism

C. Elias, Charlotte E. Lee, D. Shin, 2019, Experimental & Molecular Medicine.

FGF21 regulates circadian behavior and metabolism by acting on the nervous system

S. Kliewer, J. Takahashi, A. Bookout, 2013, Nature medicine.

Segregation of Acute Leptin and Insulin Effects in Distinct Populations of Arcuate Proopiomelanocortin Neurons

Kevin W. Williams, Joel K. Elmquist, Carol F. Elias, 2010, The Journal of Neuroscience.

PPARγ in vagal neurons regulates high-fat diet induced thermogenesis.

A. Bookout, D. Mangelsdorf, J. Elmquist, 2014, Cell metabolism.

Circuits controlling energy balance and mood: inherently intertwined or just complicated intersections?

J. Elmquist, Syann Lee, Chen Liu, 2014, Cell metabolism.

Nav1.8 neurons are involved in limiting acute phase responses to dietary fat

A. Bookout, J. Elmquist, P. Scherer, 2017, Molecular metabolism.

Liver X Receptors Protect Dorsal Root Ganglia from Obesity-Induced Endoplasmic Reticulum Stress and Mechanical Allodynia

A. Bookout, Syann Lee, L. Gautron, 2018, Cell reports.

Laser‐capture microdissection and transcriptional profiling of the dorsomedial nucleus of the hypothalamus

B. Lowell, A. Bookout, J. Elmquist, 2012, The Journal of comparative neurology.

Prader-Willi syndrome transcripts are expressed in phenotypically significant regions of the developing mouse brain.

R. Wevrick, Syann Lee, C. L. Walker, 2003, Gene expression patterns : GEP.

The hypothalamic regulation of metabolic adaptations to exercise

J. Elmquist, Syann Lee, T. Fujikawa, 2017, Journal of neuroendocrinology.

1 Desacetyl-α-melanocyte stimulating hormone and α-melanocyte 1 stimulating hormone are required to regulate energy balance 2 3

J. Elmquist, C. Buchanan, A. Coll, 2017 .