C. Partch

发表

Molecular architecture of the mammalian circadian clock.

J. Takahashi, C. Green, C. Partch, 2014, Trends in cell biology.

Cancer/Testis Antigen PASD1 Silences the Circadian Clock.

A. Banham, Stacy L. Harvey, A. Michael, 2015, Molecular cell.

n bHLH-PAS proteins : functional specification through modular domain architecture

A. Michael, C. Partch, A. Michael, 2014 .

Structure, function, and mechanism of the core circadian clock in cyanobacteria

S. Golden, A. LiWang, C. Partch, 2018, The Journal of Biological Chemistry.

CRY2 missense mutations suppress P53 and enhance cell growth

K. Lamia, C. Partch, Michael J. Bollong, 2021, Proceedings of the National Academy of Sciences.

An imPERfect link to cancer?

C. Partch, 2014, Cell cycle.

PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period

Clarisse G. Ricci, J. Mccammon, S. Tripathi, 2022, bioRxiv.

Regulating behavior with the flip of a translational switch

C. Partch, Efraín Ceh-Pavia, 2018, Proceedings of the National Academy of Sciences.

Ketogenesis impact on liver metabolism revealed by proteomics of lysine β-hydroxybutyrylation

Yingming Zhao, P. Sassone-Corsi, K. Koronowski, 2021, bioRxiv.

Casein kinase 1 dynamics underlie substrate selectivity and the PER2 circadian phosphoswitch

Clarisse G. Ricci, S. Tripathi, D. Virshup, 2020, eLife.

A Slow Conformational Sw itch in the BMAL 1 Transactivation Domain Modulates Circadian Rhythms Graphical

A. C. Liu, Hsiau-Wei Lee, Haiyan Xu, 2017 .

Purification and characterization of a type III photolyase from Caulobacter crescentus.

I. Kavakli, A. Sancar, Ya-Ting Kao, 2008, Biochemistry.

The human CRY1 tail controls circadian timing by regulating its association with CLOCK:BMAL1

Hsiau-Wei Lee, C. Partch, Jennifer L. Fribourgh, 2020, Proceedings of the National Academy of Sciences.

The CRY1 tail controls circadian timing by regulating its association with CLOCK:BMAL1

Hsiau-Wei Lee, C. Partch, Jennifer L. Fribourgh, 2019, bioRxiv.

Coactivator recruitment: A new role for PAS domains in transcriptional regulation by the bHLH‐PAS family

K. Gardner, C. Partch, 2010, Journal of cellular physiology.

Coupling of distant ATPase domains in the circadian clock protein KaiC

Archana G. Chavan, G. Lander, S. Golden, 2022, Nature Structural & Molecular Biology.

Hidden conformations differentiate day and night in a circadian pacemaker

Archana G. Chavan, G. Lander, S. Golden, 2021, bioRxiv.

UNIVERSITY OF CALIFORNIA SANTA CRUZ UNLOCKING THE THERAPEUTIC POTENTIAL OF AGOUTI SIGNALING PEPTIDE A thesis submitted in partial satisfaction of the requirements for the degree of MASTER OF SCIENCE in CHEMISTRY by

G. Millhauser, S. M. Rubin, C. Partch, 2016 .

Role of structural plasticity in signal transduction by the cryptochrome blue-light photoreceptor.

Andrew L. Lee, M. Clarkson, A. Sancar, 2005, Biochemistry.

The three Rs of transcription: recruit, retain, and recycle.

K. Gardner, Laura B. Motta-Mena, C. Partch, 2010, Molecular cell.

Casein Kinase 1 dynamics underlie the PER2 circadian phosphoswitch

Clarisse G. Ricci, S. Tripathi, D. Virshup, 2019, bioRxiv.

Assembly and function of bHLH–PAS complexes

C. Partch, Jennifer L. Fribourgh, 2017, Proceedings of the National Academy of Sciences.

CHRONO participates in multi-modal repression of circadian transcriptional complexes

C. Partch, E. Chen, P. Crosby, 2022, bioRxiv.

UNIVERSITY OF CALIFORNIA SANTA CRUZ WHEN THE TIME IS RIGHT: REGULATION OF CELL DIVISION IN DROSOPHILA A dissertation submitted in partial satisfaction of the requirements for the degree of DOCTOR OF PHILOSOPHY in MOLECULAR, CELL AND DEVELOPMENTAL BIOLOGY by

W. Sullivan, J. Tamkun, C. Partch, 2018 .

Analysis of Protein Stability and Ligand Interactions by Thermal Shift Assay

C. Partch, K. Huynh, 2015, Current protocols in protein science.

Formation of a repressive complex in the mammalian circadian clock is mediated by the secondary pocket of CRY1

Dina Schneidman-Duhovny, Greg L. Hura, Greg L Hura, 2017, Proceedings of the National Academy of Sciences.

Structure and function of animal cryptochromes.

A. Sancar, C. Selby, C. Partch, 2007, Cold Spring Harbor symposia on quantitative biology.

Antibacterial membrane attack by a pore-forming intestinal C-type lectin

Michael Grabe, Carrie L. Partch, Qiu-Xing Jiang, 2013, Nature.

Molecular basis for peptidoglycan recognition by a bactericidal lectin

Carrie L. Partch, Kevin H. Gardner, K. Gardner, 2010, Proceedings of the National Academy of Sciences.

Coactivators necessary for transcriptional output of the hypoxia inducible factor, HIF, are directly recruited by ARNT PAS-B

K. Gardner, C. Partch, 2011, Proceedings of the National Academy of Sciences.

A Slow Conformational Switch in the BMAL1 Transactivation Domain Modulates Circadian Rhythms.

A. C. Liu, Hsiau-Wei Lee, Haiyan Xu, 2017, Molecular cell.

Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5

A. Sancar, C. Selby, C. Partch, 2006, Proceedings of the National Academy of Sciences.

Emerging Models for the Molecular Basis of Mammalian Circadian Timing

C. Partch, Chelsea L. Gustafson, 2014, Biochemistry.

Conformationally responsive dyes enable protein-adaptive differential scanning fluorimetry

D. Fourches, J. Gestwicki, D. Vocadlo, 2023, bioRxiv.

NF-κB modifies the mammalian circadian clock through interaction with the core clock protein BMAL1

J. Hogenesch, A. C. Liu, L. Francey, 2020, bioRxiv.

Regulating the ARNT/TACC3 axis: multiple approaches to manipulating protein/protein interactions with small molecules.

K. Gardner, J. Key, H. Wurdak, 2013, ACS chemical biology.

Animal Cryptochromes: Divergent Roles in Light Perception, Circadian Timekeeping and Beyond

R. V. Van Gelder, A. Michael, C. Partch, 2017, Photochemistry and photobiology.

Photochemistry and Photobiology of Cryptochrome Blue-light Photopigments: The Search for a Photocycle

A. Sancar, C. Partch, 2005, Photochemistry and photobiology.

Further evidence for the role of cryptochromes in retinohypothalamic photoreception/phototransduction.

A. Sancar, C. Selby, C. Partch, 2004, Brain research. Molecular brain research.

Crystal structure of cryptochrome 3 from Arabidopsis thaliana and its implications for photolyase activity

J. Deisenhofer, Barbara S. Smith, Yihua Huang, 2006, Proceedings of the National Academy of Sciences.

Biochemical mechanisms of period control within the mammalian circadian clock.

C. Partch, J. Philpott, Rachel L. Harold, 2021, Seminars in cell & developmental biology.

Cryptochromes and circadian photoreception in animals.

A. Sancar, C. Partch, 2005, Methods in enzymology.

The tail of cryptochromes: an intrinsically disordered cog within the mammalian circadian clock

C. Partch, G. C. G. Parico, 2020, Cell communication and signaling : CCS.

Quantification of protein abundance and interaction defines a mechanism for operation of the circadian clock

A. Loudon, K. Strimmer, M. Hastings, 2022, eLife.

Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing

T. Hirota, F. Tama, G. Lander, 2020, eLife.

Cryptochrome 1 regulates the circadian clock through dynamic interactions with the BMAL1 C-terminus

A. C. Liu, Hsiau-Wei Lee, S. Khan, 2015, Nature Structural &Molecular Biology.

Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex

Hong Zhang, Seung-Hee Yoo, J. Takahashi, 2012, Science.

Orchestration of circadian timing by macromolecular protein assemblies.

C. Partch, 2020, Journal of molecular biology.

Cryptochrome proteins regulate the circadian intracellular behavior and localization of PER2 in mouse suprachiasmatic nucleus neurons

A. Loudon, M. Hastings, J. Chin, 2022, Proceedings of the National Academy of Sciences.

Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking

E. Maywood, M. Hastings, P. Nolan, 2016, Proceedings of the National Academy of Sciences.

Coiled-coil Coactivators Play a Structural Role Mediating Interactions in Hypoxia-inducible Factor Heterodimerization*

K. Gardner, D. Tomchick, C. Partch, 2015, The Journal of Biological Chemistry.

Cancer / Testis Antigen PA SD 1 Silences the Circadian Clock Graphical

A. Banham, Stacy L. Harvey, A. Michael, 2015 .

Molecular Basis of Coiled Coil Coactivator Recruitment by the Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT)*

K. Gardner, Carlos A Amezcua, C. Partch, 2009, Journal of Biological Chemistry.

New insights into non-transcriptional regulation of mammalian core clock proteins

C. Partch, P. Crosby, 2020, Journal of Cell Science.

CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch

Daniel B. Forger, Jae Kyoung Kim, D. Forger, 2018, Proceedings of the National Academy of Sciences.

Regulation of C-type Lectin Antimicrobial Activity by a Flexible N-terminal Prosegment*S⃞

K. Gardner, L. Hooper, C. Bevins, 2009, Journal of Biological Chemistry.

Structural basis of the day-night transition in a bacterial circadian clock

Susan E. Cohen, Archana G. Chavan, S. Golden, 2017, Science.

Structural dynamics of RbmA governs plasticity of Vibrio cholerae biofilms

K. Drescher, F. Yildiz, L. Dietrich, 2017, eLife.

Reconstitution of an intact clock reveals mechanisms of circadian timekeeping

Archana G. Chavan, S. Golden, S. Tripathi, 2021, Science.

Structural mimicry confers robustness in the cyanobacterial circadian clock

Clive R. Bagshaw, S. Golden, A. LiWang, 2020, bioRxiv.

Protocols for in vitro reconstitution of the cyanobacterial circadian clock

Archana G. Chavan, S. Golden, A. LiWang, 2023, Biopolymers.

Reconstitution of an intact clock that generates circadian DNA binding in vitro

Archana G. Chavan, S. Golden, A. LiWang, 2020, bioRxiv.

Isoform-specific C-terminal phosphorylation drives autoinhibition of Casein Kinase 1

Hsiau-Wei Lee, D. Virshup, C. Partch, 2023, bioRxiv.

Regulation of the circadian clock in C. elegans by clock gene homologs kin-20 and lin-42

S. Tripathi, D. Golombek, C. Partch, 2023, bioRxiv.

Protein dynamics regulate distinct biochemical properties of cryptochromes in mammalian circadian rhythms

Florence Tama, Christin Rakers, Carrie L. Partch, 2019, bioRxiv.

Cooperation between bHLH transcription factors and histones for DNA access

D. Schübeler, J. Zuber, J. Seebacher, 2023, Nature.

How circadian clocks keep time: the discovery of slowness

C. Partch, M. Brunner, 2022, FEBS letters.

Quantification of circadian interactions and protein abundance defines a mechanism for operational stability of the circadian clock

A. Loudon, K. Strimmer, T. House, 2021, bioRxiv.

Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5

A. Sancar, C. Selby, C. Partch, 2006, Proceedings of the National Academy of Sciences.

Formation of a repressive complex in the mammalian circadian clock is mediated by the secondary pocket of CRY1

Greg L. Hura, J. Takahashi, D. Schneidman-Duhovny, 2017, Proceedings of the National Academy of Sciences.

CHRONO participates in multi-modal repression of circadian transcriptional complexes

C. Partch, Chelsea L. Gustafson, G. C. G. Parico, 2023, bioRxiv.

Molecular basis for peptidoglycan recognition by a bactericidal lectin

K. Gardner, W. Goldman, L. Hooper, 2010, Proceedings of the National Academy of Sciences.

Structural dynamics of RbmA governs plasticity of Vibrio cholerae biofilms

K. Drescher, F. Yildiz, L. Dietrich, 2017, eLife.

PAS dimerization at the nexus of the mammalian circadian clock.

C. Partch, Diksha Sharma, 2023, Journal of molecular biology.

bHLH-PAS proteins: functional specification through modular domain architecture

A. Michael, C. Partch, 2013 .

Clock gene homologs lin-42 and kin-20 regulate circadian rhythms in C. elegans

S. Tripathi, D. Golombek, C. Partch, 2024, Scientific reports.

A conserved chronobiological complex times C. elegans development

H. Grosshans, C. Partch, J. M. Ragle, 2024, bioRxiv.

PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period.

Clarisse G. Ricci, S. Tripathi, D. Virshup, 2023, Molecular cell.

Protein-adaptive differential scanning fluorimetry using conformationally responsive dyes.

D. Vocadlo, C. Partch, Matthew G. Alteen, 2024, Nature biotechnology.

Isoform-specific C-terminal phosphorylation drives autoinhibition of Casein Kinase 1

Hsiau-Wei Lee, S. Tripathi, D. Virshup, 2024, bioRxiv.

The inner workings of an ancient biological clock.

A. LiWang, C. Partch, Susan S. Golden, 2024, Trends in biochemical sciences.

AI is a viable alternative to high throughput screening: a 318-target study

Eva M García-Cuesta, Frederick S. Vizeacoumar, Stephen J. Capuzzi, 2024, Scientific reports.

Cytosolic BMAL1 moonlights as a translation factor.

A. Michael, C. Partch, H. Asimgil, 2015, Trends in biochemical sciences.

Structure, function, and mechanism of the core circadian clock in cyanobacteria

S. Golden, A. LiWang, C. Partch, 2018, The Journal of Biological Chemistry.

Mechanisms of Output Signaling from a Circadian Oscillator

A. LiWang, C. Partch, J. Swan, 2018 .