J. Sirviö

发表

Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human α‐synuclein

R. Blakely, James H. Thomas, R. Nass, 2003, Journal of neurochemistry.

Ultra-slow oscillation (0.025 Hz) triggers hippocampal afterdischarges in Wistar rats

G Buzsáki, J. Csicsvari, G. Buzsáki, 1999, Neuroscience.

Effects of nicotine on neocortical electrical activity in rats.

J. Sirviö, P. Riekkinen, M. Riekkinen, 1993, The Journal of pharmacology and experimental therapeutics.

Effects of quisqualic acid nucleus basalis lesioning on cortical EEG, passive avoidance and water maze performance

R. Miettinen, J. Sirviö, P. Riekkinen, 1990, Brain Research Bulletin.

Regulation of Neocortical Electrical Activity by Cholinergic and Noradrenergic Systems

J. Sirviö, P. RiekkinenJr., P. Riekkinen, 1990 .

Somatostatin-like immunoreactivity in cerebrospinal fluid of patients with complex partial epilepsy.

A. Pitkänen, J. Sivenius, J. Sirviö, 1988, European neurology.

Effects of tetrahydroaminoacridine on spatial navigation of nucleus-basalis- and frontal-cortex-lesioned rats

J. Sirviö, P. Riekkinen, M. Riekkinen, 1992, Pharmacology Biochemistry and Behavior.

Effects of THA on passive avoidance and spatial performance in quisqualic acid nucleus basalis-lesioned rats

J. Sirviö, P. Riekkinen, Minna Aaltonen, 1991, Pharmacology Biochemistry and Behavior.

Effects of THA on passive avoidance retention performance of intact, nucleus basalis, frontal cortex and nucleus basalis + frontal cortex-lesioned rats

J. Sirviö, P. Riekkinen, M. Riekkinen, 1991, Pharmacology Biochemistry and Behavior.

Increased GABAergic transmission aggravates nucleus basalis magnocellularis lesion-induced behavioral deficits

P. Jäkälä, J. Sirviö, M. Mazurkiewicz, 1991, Brain Research Bulletin.

The correlation of passive avoidance deficit in aged rat with the loss of nucleus basalis choline acetyltransferase-positive neurons

R. Miettinen, J. Sirviö, P. Riekkinen, 1990, Brain Research Bulletin.

An arylthiazyne derivative is a potent inhibitor of lipid peroxidation and ferroptosis providing neuroprotection in vitro and in vivo

Mikko T. Huuskonen, J. Koistinaho, P. Korhonen, 2021, Scientific Reports.

Neurotransmitter markers in the cerebrospinal fluid of normal subjects effects of aging and other confounding factors

H. Soininen, P. Hartikainen, P. Riekkinen, 2005, Journal of Neural Transmission / General Section JNT.

Non-reversal of scopolamine- or age-related EEG changes by ondansetron, methysergide or alaproclate

J. Sirviö, P. Riekkinen, 2005, Psychopharmacology.

Serotonin Depletion Decreases Therapeutic Effect of THA and Nicotine

J. Sirviö, P. Riekkinen, M. Riekkinen, 1994 .

Cholinergic drugs regulate passive avoidance performance via the amygdala.

J. Sirviö, P. Riekkinen, M. Riekkinen, 1993, The Journal of pharmacology and experimental therapeutics.

5 -HT1A Receptor agonist (8-OH-DPAT) and 5-HT2 receptor agonist (DOI) disrupt the non-cognitive performance of rats in a working memory task

J. Sirviö, A. Haapalinna, P. Riekkinen, 1998, Journal of psychopharmacology.

Different forms of brain acetylcholinesterase and muscarinic binding in Parkinson's disease

J. Rinne, J. Sirviö, U. Rinne, 1989, Journal of the Neurological Sciences.

Cholinergic binding in the hippocampus of the aging male rat.

J. Sirviö, A. Hervonen, P. Riekkinen, 1988, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

Pre- and postsynaptic markers of cholinergic neurons in the cerebral cortex of rats of different ages

J. Sirviö, A. Hervonen, P. Riekkinen, 1988, Experimental Gerontology.

Sodium dependent uptake of 3H-choline in the cerebral cortex of ageing male rats.

J. Sirviö, A. Hervonen, P. Riekkinen, 1988, Pharmacology & toxicology.

Somatostatin, neuropeptide Y, GABA and cholinergic enzymes in brain of pentylenetetrazol-kindled rats

M. Beal, K. Swartz, J. Sirviö, 1989, Neuropeptides.

Recent progress in the research of Alzheimer's disease.

H. Soininen, E. Helkala, P. Riekkinen, 1987, Medical biology.

Effect of cysteamine on levels of somatostatin-like immunoreactivity and catecholamines and on electroencephalogram in the rat brain

V. Jousmäki, A. Pääkkönen, J. Sirviö, 1989, Neuropeptides.

Somatostatin-like immunoreactivity and somatostatin receptor binding in rat brain in pentylenetetrazol-induced kindling

A. Pitkänen, J. Sirviö, J. Jolkkonen, 1988, Peptides.

Pharmacological properties, central nervous system effects, and potential therapeutic applications of atipamezole, a selective alpha2-adrenoceptor antagonist.

A. Pertovaara, J. Sirviö, A. Haapalinna, 2006, CNS drug reviews.

Age dependence of somatostatin levels and somatostatin binding in the rat brain.

A. Pitkänen, J. Sirviö, J. Jolkkonen, 1987, Comparative biochemistry and physiology. A, Comparative physiology.

Spatial Learning and Noradrenaline Content in the Brain and Periphery of Young and Aged Rats

H. Lahtinen, J. Sirviö, P. Riekkinen, 1994, Experimental Neurology.

The levels of somatostatin in the brain and CSF of rat after carbamazepine administration.

A. Pitkänen, H. Sarlund, J. Hyttinen, 1989, Pharmacology & toxicology.

Pharmacological characterization and CNS effects of a novel highly selective α2C‐adrenoceptor antagonist JP‐1302

J. Sirviö, J. Sallinen, A. Haapalinna, 2007, British journal of pharmacology.

Alpha-adrenoceptor-mediated modulation of 5-HT2 receptor agonist induced impulsive responding in a 5-choice serial reaction time task.

J. Sirviö, A. Haapalinna, Tiina Koskinen, 2003, Pharmacology & toxicology.

Atipamezole, an alpha2-adrenoceptor antagonist, augments the effects of L-DOPA on evoked dopamine release in rat striatum.

A. Ylinen, J. Sirviö, A. Haapalinna, 2003, European journal of pharmacology.

Effects of single and repeated administration of vigabatrin on the performance of non-epileptic rats in a delayed non-matching to position task

J. Sirviö, M. Mazurkiewicz, P. Riekkinen, 1993, Epilepsy Research.

Age-dependence of the solubility fractions of acetylcholinesterase in the cerebral cortex and cerebellum of the rat

J. Sirviö, A. Hervonen, P. Riekkinen, 1989, Neuroscience Letters.

The molecular forms of acetylcholinesterase in cerebrospinal fluid of normal subjects — effect of aging

P. Hartikainen, J. Sirviö, P. Riekkinen, 2005, Journal of Neural Transmission / General Section JNT.

Brain amines and neocortical EEG in young and aged rats.

J. Sirviö, P. Riekkinen, A. Valjakka, 1990, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

Somatostatin-like immunoreactivity and somatostatin receptor binding in rat brain before and after pentylenetetrazol-induced convulsion

A. Pitkänen, J. Sirviö, J. Jolkkonen, 1986, Neuropeptides.

Serotonin depletion decreases the therapeutic effect of nicotine, but not THA, in medial septal-lesioned rats

J. Sirviö, P. Riekkinen, M. Riekkinen, 1994, Brain Research.

Pharmacological Characterisation of a Structurally Novel α2C ‐Adrenoceptor Antagonist ORM‐10921 and its Effects in Neuropsychiatric Models

H. Tanila, J. Sirviö, P. Piepponen, 2013, Basic & clinical pharmacology & toxicology.

Combined treatment with a 5HT1A receptor agonist and a muscarinic acetylcholine receptor antagonist disrupts water maze navigation behavior

J. Sirviö, P. Riekkinen, M. Riekkinen, 1995, Psychopharmacology.

Preserved induction of long-term potentiation in the stratum radiatum in the CA1 field of hippocampal slices from transgenic mice overexpressing ornithine decarboxylase and overproducing putrescine.

J. Larson, L. Alhonen, J. Sirviö, 1998, Synapse.

Lack of Relationship Between Thalamic Oscillations and Attention in Rats: Differential Modulation by an Alpha-2 Antagonist

P. Jäkälä, J. Sirviö, A. Haapalinna, 1997, Brain Research Bulletin.

Modulation of rat neocortical high-voltage spindle activity by 5-HT1/5-HT2 receptor subtype specific drugs.

P. Jäkälä, J. Sirviö, P. Riekkinen, 1995, European journal of pharmacology.

The behavioral effects of serotonin synthesis inhibition and quisqualic acid induced lesions of the nucleus basalis magnocellularis in rats.

P. Jäkälä, J. Sirviö, M. Mazurkiewicz, 1993, General pharmacology.

The effects of p-chlorophenylalanine-induced serotinin synthesis inhibition and muscarinic blockade on the performance of rats in a 5-choice serial reaction time task

L. Acsády, P. Jäkälä, J. Sirviö, 1992, Behavioural Brain Research.

Continuous alpha 2-adrenoceptor blockade by atipamezole decreases neocortical high-voltage spindle activity in rats.

P. Jäkälä, J. Sirviö, A. Haapalinna, 1992, European journal of pharmacology.

The effects of alaproclate and p-chlorophenylalanine on cued navigation performance in rats

P. Jäkälä, J. Sirviö, P. Riekkinen, 1992, Journal of neural transmission. Parkinson's disease and dementia section.

Pharmacological consequences of cholinergic plus serotonergic manipulations

R. Miettinen, J. Sirviö, P. Riekkinen, 1991, Brain Research.

The effects of increased serotonergic and decreased cholinergic activities on spatial navigation performance in rats

P. Jäkälä, J. Sirviö, P. Riekkinen, 1991, Pharmacology Biochemistry and Behavior.

The effects of THA on scopolamine and nucleus basalis lesion-induced EEG slowing

P. Jäkälä, R. Miettinen, J. Sirviö, 1991, Brain Research Bulletin.

Relationship between the cortical choline acetyltransferase content and EEG delta-power

J. Sirviö, P. Riekkinen, Paavo Riekkinen, 1990, Neuroscience Research.

Brain cholinergic enzymes and cortical EEG activity in young and old rats.

J. Partanen, A. Pääkkönen, J. Sirviö, 1989, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

α2-Adrenergic drug effects on brain monoamines, locomotion, and body temperature are largely abolished in mice lacking the α2A-adrenoceptor subtype

M. Scheinin, J. Sirviö, J. Sallinen, 2003, Neuropharmacology.

Effects of D-cycloserine, a positive modulator of N-methyl-D-aspartate receptors, and ST 587, a putative alpha-1 adrenergic agonist, individually and in combination, on the non-delayed and delayed foraging behaviour of rats assessed in the radial arm maze

J. Sirviö, R. Pussinen, 1999, Journal of psychopharmacology.

Preserved induction of long‐term potentiation in the stratum radiatum in the CA1 field of hippocampal slices from transgenic mice overexpressing ornithine decarboxylase and overproducing putrescine

J. Larson, L. Alhonen, J. Sirviö, 1998 .

Minor role for α1‐adrenoceptors in the facilitation of induction and early maintenance of long‐term potentiation in the CA1 field of the hippocampus

J. Sirviö, R. Pussinen, 1998, Journal of neuroscience research.

Stimulation of alpha-1 adrenergic receptors facilitates spatial learning in rats

J. Sirviö, A. Haapalinna, P. Riekkinen, 1998, European Neuropsychopharmacology.

Effects of St-587 and prazosin on water maze and passive avoidance performance of scopolamine-treated rats

J. Sirviö, P. Riekkinen, S. Ruotsalainen, 1996, Pharmacology Biochemistry and Behavior.

The effects of a specific alpha(2)-adrenoceptor antagonist, atipamezole, on cognitive performance and brain neurochemistry in aged Fisher 344 rats.

J. Sirviö, A. Haapalinna, E. Macdonald, 2000, European journal of pharmacology.

A long-term follow-up study of cerebrospinal fluid acetylcholinesterase in delirium

E. Leinonen, U. Lepola, J. Sirviö, 2005, European Archives of Psychiatry and Clinical Neuroscience.

Effects of noradrenergic DSP4 lesion on the effectiveness of pilocarpine in reversing scopolamine-induced amnesia

J. Sirviö, P. Riekkinen, T. Ekonsalo, 1992, Brain Research Bulletin.

Effect of alpha2 antagonists and an agonist on EEG slowing induced by scopolamine and lesion of the nucleus basalis

P. Jäkälä, R. Lammintausta, J. Sirviö, 1990, Neuropharmacology.

Guanfacine, But Not Clonidine, Improves Planning and Working Memory Performance in Humans

P. Jäkälä, J. Sirviö, P. Riekkinen, 1999, Neuropsychopharmacology.

Stimulation and blockade of α1 adrenoceptors affect behavioural activity, but not spatial working memory assessed by delayed non-matching to position task in rats

J. Sirviö, Tarja Puumala, 1997, Journal of psychopharmacology.

Comparative effects of alpha-2 receptor agents and THA on the performance of adult and aged rats in the delayed non-matching to position task

J. Sirviö, A. Haapalinna, P. Riekkinen, 2005, Psychopharmacology.

The α2-adrenoceptor antagonist atipamezole reduces the development and expression of d-amphetamine-induced behavioural sensitization

M. Scheinin, E. Korpi, J. Sirviö, 2003, Naunyn-Schmiedeberg's Archives of Pharmacology.

An α2-adrenergic antagonist, atipamezole, facilitates behavioral recovery after focal cerebral ischemia in rats

J. Sivenius, J. Sirviö, A. Haapalinna, 2001, Neuropharmacology.

Overexpression of Alpha2C-adrenoceptors impairs water maze navigation

M. Scheinin, J. Sirviö, J. Sallinen, 1999, Neuroscience.

Comparison of the effects of acute and subchronic administration of atipamezole on reaction to novelty and active avoidance learning in rats

J. Sirviö, A. Haapalinna, T. Viitamaa, 1999, Naunyn-Schmiedeberg's Archives of Pharmacology.

Activation of muscarinic M3-like receptors and β-adrenoceptors, but not M2-like muscarinic receptors or α-adrenoceptors, directly modulates corticostriatal neurotransmission in vitro

J. Larson, J. Sirviö, A. Haapalinna, 1999, Neuroscience.

Alpha2C-adrenoceptor overexpression disrupts execution of spatial and non-spatial search patterns

M. Scheinin, B. Kobilka, J. Sirviö, 1999, Neuroscience.

Systemic Administration of Atipamezole, a Selective Antagonist of Alpha-2 Adrenoceptors, Facilitates Behavioural Activity but does not Influence Short-term or Long-term Memory in Trimethyltin-intoxicated and Control Rats

J. Sirviö, A. Haapalinna, J. Jolkkonen, 1998, Neuroscience & Biobehavioral Reviews.

Alpha2C-adrenoceptor-overexpressing mice are impaired in executing nonspatial and spatial escape strategies.

M. Scheinin, B. Kobilka, P. Jäkälä, 1998, Molecular pharmacology.

Alpha2-adrenergic control of dopamine overflow and metabolism in mouse striatum.

J. Sirviö, A. Haapalinna, E. Macdonald, 1997, European journal of pharmacology.

Modulation of Vigilance and Behavioral Activation by Alpha-1 Adrenoceptors in the Rat

J. Sirviö, P. Riekkinen, T. Puumala, 1997, Pharmacology Biochemistry and Behavior.

Dexmedetomidine Reduces Response Tendency, but Not Accuracy of Rats in Attention and Short-Term Memory Tasks

J. Sirviö, A. Haapalinna, P. Riekkinen, 1997, Pharmacology Biochemistry and Behavior.

The effects of selective alpha-2 adrenergic agents on the performance of rats in a 5-choice serial reaction time task

H. Lahtinen, J. Sirviö, A. Haapalinna, 1994, Brain Research Bulletin.

Some unusual effects of α 2-adrenergic drugs on cortical high voltage spindles in rats

J. Sirviö, A. Haapalinna, P. Riekkinen, 1994, European Neuropsychopharmacology.

Dose- and parameter-dependent effects of atipamezole, an α 2-antagonist, on the performance of rats in a five-choice serial reaction time task

P. Jäkälä, J. Sirviö, A. Haapalinna, 1993, Pharmacology Biochemistry and Behavior.

α1-Adrenoceptor antagonist decreased α2-adrenoceptor antagonist-induced high voltage spindle suppression in adult and aged rats

R. Lammintausta, J. Sirviö, P. Riekkinen, 1993 .

Effects of atipamezole, an α 2-adrenoceptor antagonist, on the performance of rats in a five-choice serial reaction time task

P. Jäkälä, J. Sirviö, A. Haapalinna, 1992, Pharmacology Biochemistry and Behavior.

The Role of the Noradrenergic System in Higher Cerebral Functions: Experimental Studies about the Effects of Noradrenergic Modulation on Electrophysiology and Behavior

P. Jäkälä, R. Lammintausta, J. Sirviö, 1992 .

The effects of alpha-2 adrenoceptor antagonist, atipamezole, on spatial learning in scopolamine-treated and aged rats

R. Lammintausta, M. Airaksinen, J. Sirviö, 1992, Journal of neural transmission. Parkinson's disease and dementia section.

The effects of atipamezole, an Alpha-2 antagonist, on the performance of young and aged rats in the delayed nonmatching to position task

A. Pennanen, J. Sirviö, P. Riekkinen, 1991, Pharmacology Biochemistry and Behavior.

Inhibition of MAO-A activity enhances behavioural activity of rats assessed using water maze and open arena tasks.

A. Barbelivien, J. Sirviö, A. Haapalinna, 2001, Pharmacology & toxicology.

Central alpha1-adrenoceptors: their role in the modulation of attention and memory formation.

J. Sirviö, E. Macdonald, Jouni Sirviö, 1999, Pharmacology & therapeutics.

Adenohypophyseal hormone levels during hyperthermia.

A. Pitkänen, J. Sirviö, J. Jolkkonen, 1987, Endocrinologie.

d-Cycloserine, a partial agonist at the glycine site, enhances the excitability of dentate granule cells in vivo in rats.

H. Lahtinen, J. Sirviö, P. Riekkinen, 1994, European journal of pharmacology.

Changes in activities of dopamine and serotonin systems in the frontal cortex underlie poor choice accuracy and impulsivity of rats in an attention task

J. Sirviö, J Sirviö, T Puumala, 1998, Neuroscience.

The role of the dorsal raphe–serotonergic system and cholinergic receptors in the modulation of working memory

R. Miettinen, J. Sirviö, M. Riekkinen, 1997, Neuroscience & Biobehavioral Reviews.

Strategies That Support Declining Cholinergic Neurotransmission in Alzheimer’s Disease Patients

J. Sirviö, 1999, Gerontology.

Behavioral and Pharmacological Studies on the Validation of a New Animal Model for Attention Deficit Hyperactivity Disorder

P. Jäkälä, J. Sirviö, P. Riekkinen, 1996, Neurobiology of Learning and Memory.

Hippocampal mobility-related theta activity is not diminished by vigabatrin, a GABAmimetic antiepileptic drug, in normal rats

A. Ylinen, T. Freund, J. Sirviö, 1992, Brain Research Bulletin.

The effect of γ-vinyl-GABA on the performance of nucleus basalis-lesioned rats in spatial navigation task

J. Sirviö, P. Riekkinen, Tuula Hannila, 1990, Brain Research.

Blockade of muscarinic, rather than nicotinic, receptors impairs attention, but does not interact with serotonin depletion

J. Sirviö, E. Koivisto, S. Ruotsalainen, 2000, Psychopharmacology.

Additive deficits in the choice accuracy of rats in the delayed non-matching to position task after cholinolytics and serotonergic lesions are non-mnemonic in nature

P. Riekkinen Sr., R. Miettinen, J. Sirviö, 1997, Psychopharmacology.

Effects of combined methysergide and mecamylamine/scopolamine treatment on spatial navigation

J. Sirviö, P. Riekkinen, M. Riekkinen, 1992, Brain Research.

Effects of concurrent nicotinic antagonist and PCPA treatments on spatial and passive avoidance learning

J. Sirviö, P. Riekkinen, M. Riekkinen, 1992, Brain Research.

Effects of concurrent manipulations of nicotinic and muscarinic receptors on spatial and passive avoidance learning

J. Sirviö, P. Riekkinen, Paavo Riekkinen, 1990, Pharmacology Biochemistry and Behavior.

Selegiline Combined with Enriched-Environment Housing Attenuates Spatial Learning Deficits Following Focal Cerebral Ischemia in Rats

J. Sivenius, J. Sirviö, A. Haapalinna, 2001, Experimental Neurology.

Interaction between the alpha2-noradrenergic and muscarinic Systems in the regulation of neocortical high voltage spindles

P. Jäkälä, R. Lammintausta, J. Sirviö, 1990, Brain Research Bulletin.

Clonidine, but not Guanfacine, Impairs Choice Reaction Time Performance in Young Healthy Volunteers

P. Jäkälä, J. Sirviö, P. Riekkinen, 1999, Neuropsychopharmacology.

Guanfacine and Clonidine, Alpha2-Agonists, Improve Paired Associates Learning, but not Delayed Matching to Sample, in Humans

M. Vanhanen, P. Jäkälä, J. Sirviö, 1999, Neuropsychopharmacology.

Neurochemical markers in the cerebrospinal fluid of patients with Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis and normal controls

H. Soininen, P. Hartikainen, R. Soikkeli, 1992, Journal of neural transmission. Parkinson's disease and dementia section.

Experimental studies on the role of serotonin in cognition

P. Jäkälä, J. Sirviö, P. Riekkinen, 1994, Progress in Neurobiology.

Effects of single and repeated administration of vigabatrin on the performance of rats in a 5-choice serial reaction time task

J. Sirviö, M. Mazurkiewicz, P. Riekkinen, 1992, Epilepsy Research.

Acetyl- and butyrylcholinesterase activity in the cerebrospinal fluid of patients with Parkinson's disease

H. Soininen, E. Helkala, P. Riekkinen, 1987, Journal of the Neurological Sciences.

An alpha(2)-adrenergic antagonist, atipamezole, facilitates behavioral recovery after focal cerebral ischemia in rats.

J. Sivenius, J. Sirviö, A. Haapalinna, 2001, Neuropharmacology.

The effects of dorsal noradrenergic bundle lesions on spatial learning, locomotor activity, and reaction to novelty.

M. Airaksinen, R. Miettinen, J. Sirviö, 1990, Behavioral and neural biology.

Activation of 5-HT2A receptors impairs response control of rats in a five-choice serial reaction time task

J. Sirviö, E. Koivisto, S. Ruotsalainen, 2000, Neuropharmacology.

Brain and cerebrospinal fluid cholinesterases in Alzheimer's disease, Parkinson's disease and aging. A critical review of clinical and experimental studies

J. Sirviö, P. Riekkinen, P. J. Riekkinen, 1992, Journal of neural transmission. Parkinson's disease and dementia section.

Comparison of NADPH diaphorase histochemistry, somatostatin immunohistochemistry, and silver impregnation in detecting structural and functional impairment in experimental status epilepticus

T. Halonen, R. Miettinen, J. Sirviö, 1997, Neuroscience.

Effects of ZK 93426 on muscarinic and nicotinic antagonist or nucleus basalis lesioning-induced electrocortical slowing

J. Sirviö, P. Riekkinen, M. Riekkinen, 2005, Psychopharmacology.

Neocortical, hippocampal and septal parvalbumin- and somatostatin-containing neurons in young and aged rats: Correlation with passive avoidance and water maze performance

M. Laakso, R. Miettinen, J. Sirviö, 1993, Neuroscience.

The systemic administration of tacrine or selegiline facilitate spatial learning in aged fisher 344 rats

J. Sirviö, A. Haapalinna, E. Koivisto, 2005, Journal of Neural Transmission.

d-Cycloserine, a modulator of the N-methyl-d-aspartate receptor, improves spatial learning in rats treated with muscarinic antagonist

H. Lahtinen, J. Sirviö, P. Riekkinen, 1992, Neuroscience Letters.

J. Sirviö, P. Riekkinen, 1990, Behavioural Brain Research.

Transgenic mice overexpressing truncated trkB neurotrophin receptors in neurons have impaired long‐term spatial memory but normal hippocampal LTP

E. Castrén, L. Alhonen, J. Sirviö, 2000, Synapse.

Tetrahydroaminoacridine improves passive avoidance retention defects induced by aging and medial septal lesion but not by fimbria-fornix lesion

H. Lahtinen, J. Sirviö, P. Riekkinen, 1991, Brain Research Bulletin.

A longitudinal study of cerebrospinal fluid acetylcholinesterase in delirium: Changes at the acute stage and at one-year followup

P. Riekkinen, K. Reinikainen, J. Sirviö, 1991, Psychiatry Research.

The effects of concurrent manipulations of cholinergic and noradrenergic systems on neocortical EEG and spatial learning.

J. Partanen, J. Sirviö, P. Riekkinen, 1990, Behavioral and neural biology.

Metabolic alterations in the prefrontal and cingulate cortices are related to behavioral deficits in a rodent model of attention-deficit hyperactivity disorder.

A. Barbelivien, J. Sirviö, S. Ruotsalainen, 2001, Cerebral cortex.

The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus.

E. Castrén, H. Thoenen, D. Lindholm, 1993, Neuroreport.

Loss of cholinergic neurons in the nucleus basalis induces neocortical electroencephalographic and passive avoidance deficits

R. Miettinen, J. Sirviö, P. Riekkinen, 1992, Neuroscience.

Amygdala kindling increased fear-response, but did not impair spatial memory in rats

A. Pitkänen, M. Airaksinen, J. Sirviö, 1992, Physiology & Behavior.

Cholinergic neurons in the basal forebrain of aged female mice

G. Kalesnykas, R. Miettinen, J. Sirviö, 2004, Brain Research.

Gammavinylgaba increases high voltage spindle activity in control and nucleus basalis-lesioned rats after sub-chronic treatment

J. Sirviö, P. Riekkinen, M. Riekkinen, 1991, Brain Research.

Comparison of the effects of acute and chronic ibotenic and quisqualic acid nucleus basalis lesioning

R. Miettinen, J. Sirviö, P. Riekkinen, 1991, Brain Research Bulletin.

Tetrahydroaminoacridine alleviates medial septal lesion-induced and age-related spatial reference but not working memory deficits

J. Sirviö, P. Riekkinen, Minna Aaltonen, 1991, Physiology and Behavior.

The effects of noradrenergic neurotoxin, DSP-4, on the performance of young and aged rats in spatial navigation task

J. Sirviö, J. Jolkkonen, P. Riekkinen, 1991, Brain Research.

The interaction of L-deprenyl and scopolamine on spatial learning/memory in rats

J. Sirviö, P. Riekkinen, L. Yavich, 1993, Journal of neural transmission. Parkinson's disease and dementia section.

Effects of alpha2-drugs and pilocarpine on the high-voltage spindle activity of young and aged control and DPS4-lesioned rats

P. Jäkälä, R. Lammintausta, J. Sirviö, 1991, Physiology & Behavior.

The effect of subchronic administration of vigabatrin on learning and memory in nonepileptic rats

T. Halonen, A. Ylinen, H. Lahtinen, 1991, Pharmacology Biochemistry and Behavior.

Enhancement of Intermediate-Term Memory by an Alpha-1 Agonist or a Partial Agonist at the Glycine Site of the NMDA Receptor

J. Sirviö, A. Haapalinna, P. Riekkinen, 1997, Neurobiology of Learning and Memory.

Studies on the influence of enriched-environment housing combined with systemic administration of an alpha2-adrenergic antagonist on spatial learning and hyperactivity after global ischemia in rats.

P. Riekkinen, J. Sivenius, J. Koistinaho, 1997, Stroke.

Differential effects of three 5-HT receptor antagonists on the performance of rats in attentional and working memory tasks

P. Jäkälä, J. Sirviö, P. Riekkinen, 1997, European Neuropsychopharmacology.

The effects of d-cycloserine and MK-801 on the performance of rats in two spatial learning and memory tasks

J. Sirviö, P. Riekkinen, E. Macdonald, 1995, European Neuropsychopharmacology.

Effects of atipamezole, an alpha 2-adrenoceptor antagonist, on the performance of rats in a five-choice serial reaction time task.

P. Jäkälä, J. Sirviö, P. Riekkinen, 1992, Pharmacology, biochemistry, and behavior.

Studies on the involvement of the dopaminergic system in the 5-HT2 agonist (DOI)-induced premature responding in a five-choice serial reaction time task

J. Sirviö, Tiina Koskinen, 2001, Brain Research Bulletin.

Alpha2-adrenergic drug effects on brain monoamines, locomotion, and body temperature are largely abolished in mice lacking the alpha2A-adrenoceptor subtype.

M. Scheinin, J. Sirviö, J. Sallinen, 2003, Neuropharmacology.

Somatostatin and cognitive functions in Alzheimer's disease — the relationship of cerebrospinal fluid somatostatin increase with clinical response to tetrahydroaminoacridine

E. Helkala, P. Riekkinen, K. Alhainen, 1991, Neuroscience Letters.

Joint modulation of neocortical electrical activity by nicotinic and muscarinic receptors

J. Sirviö, P. Riekkinen, E. Koivisto, 1991, Brain Research Bulletin.

In vitro and in vivo evaluation of a sulfenamide prodrug of basic metformin.

J. Leppänen, J. Rautio, J. Sirviö, 2012, Journal of pharmaceutical sciences.

The effects of d-cycloserine, a partial agonist at the glycine binding site, on spatial learning and working memory in scopolamine-treated rats

J. Sirviö, P. Riekkinen, E. Macdonald, 1995, Journal of neural transmission. Parkinson's disease and dementia section.

The effects of guanfacine, alpha-2 agonist, on the performance of young and aged rats in spatial navigation task.

J. Sirviö, P. Riekkinen, E. Koivisto, 1991, Behavioral and neural biology.

The effects of THA on medial septal lesion-induced memory defects

J. Sirviö, P. Riekkinen, Riekkinen Paavo, 1990, Pharmacology Biochemistry and Behavior.

Cholinergic enzyme activities and muscarinic binding in the cerebral cortex of rats of different age and sex.

J. Sirviö, J. Jolkkonen, A. Hervonen, 1988, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

Enriched-environment housing increases neuronal Fos-staining in the dentate gyrus after a water maze spatial learning task

J. Sivenius, J. Koistinaho, J. Sirviö, 2001, Neuropharmacology.

The 5-HT2 Receptor Activation Enhances Impulsive Responding Without Increasing Motor Activity in Rats

J. Sirviö, S. Ruotsalainen, Tiina Koskinen, 2000, Pharmacology Biochemistry and Behavior.

Improved sensorimotor function by rolipram following focal cerebral ischemia in rats.

J. Sirviö, J. Jolkkonen, Mikko Sairanen, 2008, Restorative neurology and neuroscience.

Effects of α2-adrenoceptor Agonist and Antagonist on Spatial Memory in Rats

M. Airaksinen, J. Sirviö, P. Riekkinen, 1991 .

Diminution of N-methyl-d-aspartate-induced perturbation of neurotransmission by dexmedetomidine in the CA1 field of rat hippocampus in vitro

J. Sirviö, A. Haapalinna, M. Niittykoski, 2000, Neuroscience Letters.

Cholinesterases in the cerebrospinal fluid, plasma, and erythrocytes of patients with Alzheimer's disease

H. Soininen, P. Hartikainen, P. Riekkinen, 2005, Journal of Neural Transmission.

The effects of dexmedetomidine, an alpha2 agonist, on learning and memory, assessed using passive avoidance and water maze tasks in rats

J. Sirviö, T. Ekonsalo, P. Riekkinen, 1992, Neuropharmacology.

Effects of an inhibitor of GABA-aminotransferase (γ-vinyl-GABA) on the spatial navigation deficit induced by muscarinic blockade

J. Sirviö, M. Mazurkiewicz, P. Riekkinen, 1992, Pharmacology Biochemistry and Behavior.

Effects of an inhibitor of GABA-aminotransferase (gamma-vinyl-GABA) on the spatial navigation deficit induced by nicotinic blockade.

J. Sirviö, M. Mazurkiewicz, P. Riekkinen, 1993, General pharmacology.

Selegiline reduces N-methyl-D-aspartic acid induced perturbation of neurotransmission but it leaves NMDA receptor dependent long-term potentiation intact in the hippocampus

J. Sirviö, A. Haapalinna, M. Niittykoski, 2003, Journal of Neural Transmission.

Neurophysiological consequences of combined cholinergic and noradrenergic lesions

J. Sirviö, P. Riekkinen, M. Riekkinen, 1992, Experimental Neurology.

Combination of atipamezole and tetrahydroaminoacridine/pilocarpine treatment suppresses high voltage spindle activity in aged rats

P. Jäkälä, R. Lammintausta, J. Sirviö, 1991, Brain Research Bulletin.

Effects of p-chlorophenylalanine and methysergide on the performance of a working memory task

P. Jäkälä, J. Sirviö, P. Riekkinen, 1993, Pharmacology Biochemistry and Behavior.

Methoctramine moderately improves memory but pirenzepine disrupts performance in delayed non-matching to position test.

J. Sirviö, P. Riekkinen, J. Aura, 1997, European journal of pharmacology.

The effects of tacrine and zacopride on the performance of adult rats in the working memory task.

J. Sirviö, P. Riekkinen, P. Jäkälä, 1993, General pharmacology.