C. Taslim

发表

Chromatin profiling reveals reorganization of lysine specific demethylase 1 by an oncogenic fusion protein

S. Lessnick, Sunil Sharma, K. Pishas, 2020, bioRxiv.

Transcriptomic analysis functionally maps the intrinsically disordered domain of EWS/FLI and reveals novel transcriptional dependencies for oncogenesis

S. Lessnick, K. Pishas, E. Theisen, 2019, Genes & cancer.

Integrative genome-wide chromatin signature analysis using finite mixture models

Shili Lin, T. Huang, Kun Huang, 2012, BMC Genomics.

A quantitative proteomic workflow for characterization of frozen clinical biopsies: laser capture microdissection coupled with label-free mass spectrometry.

Anjali A. Satoskar, Sashwati Roy, Chandan K. Sen, 2012, Journal of proteomics.

Molecular and Cellular Pathobiology Epigenetic Silencing Mediated through Activated PI 3 K / AKT Signaling in Breast Cancer

Sandya Liyanarachchi, Victor X Jin, Cenny Taslim, 2011 .

Racial differences in genome-wide methylation profiling and gene expression in breast tissues from healthy women

Cenny Taslim, Jo L Freudenheim, J. Freudenheim, 2015, Epigenetics.

BOG: R-package for Bacterium and virus analysis of Orthologous Groups

Jincheol Park, Shili Lin, C. Taslim, 2015, Computational and structural biotechnology journal.

Identification of two types of GGAA-microsatellites and their roles in EWS/FLI binding and gene regulation in Ewing sarcoma

S. Lessnick, C. Taslim, Kirsten M. Johnson, 2017, PloS one.

Osteosarcoma tumors maintain intra-tumoral transcriptional heterogeneity during bone and lung colonization

M. Cannon, C. Taslim, Ryan D. Roberts, 2022, bioRxiv.

Integrated analysis identifies a class of androgen-responsive genes regulated by short combinatorial long-range mechanism facilitated by CTCF

Qianben Wang, T. Huang, Kun Huang, 2012, Nucleic acids research.

Comparative study on ChIP-seq data: normalization and binding pattern characterization

Pearlly Yan, Tim Hui-Ming Huang, Kun Huang, 2009, Bioinform..

Role for the EWS domain of EWS/FLI in binding GGAA-microsatellites required for Ewing sarcoma anchorage independent growth

S. Lessnick, E. Theisen, K. R. Miller, 2017, Proceedings of the National Academy of Sciences.

Mitochondrial Dysfunction Is a Driver of SP-2509 Drug Resistance in Ewing Sarcoma

K. Stegmaier, G. Alexe, S. Lessnick, 2021, bioRxiv.

Therapeutic Targeting of KDM1A/LSD1 in Ewing Sarcoma with SP-2509 Engages the Endoplasmic Reticulum Stress Response

M. Beckerle, J. Mora, B. Crompton, 2018, Molecular Cancer Therapeutics.

The ETS transcription factor ETV6 constrains the transcriptional activity of EWS–FLI to promote Ewing sarcoma

K. Ross, M. Rivera, Diana Lu, 2023, Nature Cell Biology.

Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis.

S. Lessnick, K. Pishas, E. Theisen, 2020, Journal of visualized experiments : JoVE.

Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule-dependent Manner

S. Lessnick, P. Grohar, C. Taslim, 2019, Clinical Cancer Research.

Osteosarcoma tumors maintain intratumoral heterogeneity, even while adapting to environmental pressures that drive clonal selection

M. Cannon, C. Taslim, Ryan D. Roberts, 2020 .

Discovery and replication of microRNAs for breast cancer risk using genome-wide profiling

J. Freudenheim, P. Shields, Shiva S. Krishnan, 2016, Oncotarget.

Chromatin signature analysis and prediction of genome-wide novel promoters using finite mixture model

Tim Hui-Ming Huang, Kun Huang, Shili Lin, 2011, 2011 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS).

Practical Guidelines for the Comprehensive Analysis of ChIP-seq Data

Jie Zhang, Tao Liu, Qunhua Li, 2013, PLoS Comput. Biol..

Integrative Analysis of Epigenomics Data

Simon Lin, Cenny Taslim, Stephen L. Lessnick, 2019, Computational Epigenetics and Diseases.

Persistent alterations of gene expression profiling of human peripheral blood mononuclear cells from smokers

S. David, P. Shields, C. Loffredo, 2016, Molecular carcinogenesis.

Analyzing ChIP-seq data: preprocessing, normalization, differential identification, and binding pattern characterization.

Kun Huang, Shili Lin, Cenny Taslim, 2012, Methods in molecular biology.

Therapeutic modulation of the CD47-SIRPα axis in the pediatric tumor microenvironment: working up an appetite

T. Cripe, C. Taslim, Ajay Gupta, 2020, Cancer drug resistance.

Genetic variation in one-carbon metabolism in relation to genome-wide DNA methylation in breast tissue from heathy women.

J. Freudenheim, J. Mason, P. Shields, 2016, Carcinogenesis.

The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma

S. Lessnick, B. Sunkel, Benjamin Z. Stanton, 2020, bioRxiv.

Chromatin profiling reveals relocalization of lysine-specific demethylase 1 by an oncogenic fusion protein

S. Lessnick, Sunil Sharma, K. Pishas, 2020, Epigenetics.

Renin-sensitive microRNAs correlate with atherosclerosis plaque progression

S. Rajagopalan, G. Mihai, A. Maiseyeu, 2014, Journal of Human Hypertension.

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma

S. Lessnick, K. Pishas, E. Theisen, 2019, Oncotarget.

DIME: R-package for identifying differential ChIP-seq based on an ensemble of mixture models

Tim Hui-Ming Huang, Shili Lin, Cenny Taslim, 2011, Bioinform..

Design of experiments for steady-state system identification with applications in genetic and business network modelinG

Theodore T. Allen, Shih-Hsien Tseng, Cenny Taslim, 2020 .

EWS/FLI mediated reprogramming of 3D chromatin promotes an altered transcriptional state in Ewing sarcoma

S. Lessnick, E. Theisen, Julia Selich-Anderson, 2021, bioRxiv.

HOTAIR primes the Ewing sarcoma family of tumors for tumorigenesis via epigenetic dysregulation involving LSD1

Nilay Shah, P. White, S. Lessnick, 2018, bioRxiv.

Identification of a Novel FUS/ETV4 Fusion and Comparative Analysis with Other Ewing Sarcoma Fusion Proteins

S. Lessnick, P. Heppner, Julia Selich-Anderson, 2021, Molecular Cancer Research.

Title : Identification of a novel FUS / ETV 4 fusion and comparative analysis with 1 other Ewing sarcoma fusion proteins

S. Lessnick, P. Heppner, Julia Selich-Anderson, 2021 .

The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma

S. Lessnick, Benjamin Z. Stanton, E. Theisen, 2021, Oncogene.

The DBD-α4 helix of EWS::FLI is required for GGAA microsatellite binding that underlies genome regulation in Ewing sarcoma

E. Theisen, Julia Selich-Anderson, C. Taslim, 2024, bioRxiv.

A Mixture Modeling Framework for Differential Analysis of High-Throughput Data

Shili Lin, Cenny Taslim, Shili Lin, 2014, Comput. Math. Methods Medicine.