M. Hoogenkamp

发表

Chronic FLT3-ITD Signaling in Acute Myeloid Leukemia Is Connected to a Specific Chromatin Signature

Salam A. Assi, D. Westhead, Jason Piper, 2015, Cell reports.

Cooperative binding of AP-1 and TEAD4 modulates the balance between vascular smooth muscle and hemogenic cell fate

Salam A. Assi, V. Kouskoff, P. Cauchy, 2016, Development.

Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding

Salam A. Assi, D. Tenen, M. Care, 2012, Leukemia.

Hepatic HNF4α deficiency induces periportal expression of glutamine synthetase and other pericentral enzymes

J. Ruijter, I. Talianidis, W. Lamers, 2007, Hepatology.

Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation

Salam A. Assi, B. Göttgens, A. Lilly, 2016, Developmental cell.

PHF6 Interacts with LMO2 During Normal Haematopoiesis and in Leukaemia and Regulates Gene Expression and Genome Integrity

D. Ward, M. Hoogenkamp, V. Stanulović, 2020, bioRxiv.

The Histone Methyltransferase KMT2B Is Required for RNA Polymerase II Association and Protection from DNA Methylation at the MagohB CpG Island Promoter

A. Riggs, A. F. Stewart, C. Bonifer, 2013, Molecular and Cellular Biology.

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells.

Salam A. Assi, Nicola K. Wilson, B. Göttgens, 2011, Blood.

University of Birmingham Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding

Salam A. Assi, M. Care, D. Westhead, 2012 .

C/EBPα Activates Pre-existing and De Novo Macrophage Enhancers during Induced Pre-B Cell Transdifferentiation and Myelopoiesis

Denis Thieffry, Yang Shi, Miguel Beato, 2015, Stem cell reports.

Hepatocyte‐specific interplay of transcription factors at the far‐upstream enhancer of the carbamoylphosphate synthetase gene upon glucocorticoid induction

A. Das, W. Lamers, T. Grange, 2007, The FEBS journal.

Proliferation and Survival of T-cell Acute Lymphoblastic Leukaemia Depends on mTOR-regulated Glutamine Uptake and EAAT1-dependent Conversion of Glutamine to Aspartate and Nucleotides

U. Günther, C. Ludwig, M. Reed, 2020 .

Survival and Proliferation of T-cell Acute Lymphoblastic Leukaemia Depends on mTOR-regulated Glutamine Uptake and EAAT1 Activity

U. Günther, C. Ludwig, M. Reed, 2020 .

Macrophage development from HSCs requires PU.1-coordinated microRNA expression.

F. Rosenbauer, D. Lenze, S. Heinz, 2011, Blood.

The role of LMO 4 in T cell acute lymphoblastic leukaemia by Eleni Georgiades

M. Hoogenkamp, 2014 .

Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program.

V. Kouskoff, D. Tenen, A. Fisher, 2009, Blood.

LMO2 is required for TAL1 DNA binding activity and initiation of definitive haematopoiesis at the haemangioblast stage

Salam A. Assi, P. Cauchy, M. Hoogenkamp, 2017, Nucleic acids research.

Aberrant expression of CD19 in AML with t(8;21) involves a poised chromatin structure and PAX5

G. Follows, C. Bonifer, P. Cockerill, 2010, Oncogene.

Differentiation-dependent Alterations in Histone Methylation and Chromatin Architecture at the Inducible Chicken Lysozyme Gene*

C. Bonifer, H. Tagoh, M. Hoogenkamp, 2005, Journal of Biological Chemistry.

microRNA expression Macrophage development from HSCs requires PU.1-coordinated

F. Rosenbauer, D. Lenze, S. Heinz, 2011 .

The Pu.1 Locus Is Differentially Regulated at the Level of Chromatin Structure and Noncoding Transcription by Alternate Mechanisms at Distinct Developmental Stages of Hematopoiesis

D. Tenen, C. Bonifer, P. Cockerill, 2007, Molecular and Cellular Biology.

Functional Differences between the Long Terminal Repeat Transcriptional Promoters of Human Immunodeficiency Virus Type 1 Subtypes A through G

B. Berkhout, M. Hoogenkamp, R. Jeeninga, 2000, Journal of Virology.

cis-Regulatory Remodeling of the SCL Locus during Vertebrate Evolution

B. Göttgens, A. Green, G. Follows, 2010, Molecular and Cellular Biology.

PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element.

F. Rosenbauer, D. Tenen, Tajhal Dayaram, 2008, Genes & development.

Thee role of proximal enhancer elements in the regulation off carbamoylphosphate synthetase expression

W. Lamers, O. Schoneveld, M. Hoogenkamp, 2007 .

The role of proximal-enhancer elements in the glucocorticoid regulation of carbamoylphosphate synthetase gene transcription from the upstream response unit.

W. Lamers, O. Schoneveld, M. Hoogenkamp, 2005, Biochimie.

How transcription factors program chromatin--lessons from studies of the regulation of myeloid-specific genes.

C. Bonifer, H. Tagoh, M. Hoogenkamp, 2008, Seminars in immunology.

A Two-Step, PU.1-Dependent Mechanism for Developmentally Regulated Chromatin Remodeling and Transcription of the c-fms Gene

Nicola K. Wilson, N. Wilson, Harinder Singh, 2006, Molecular and Cellular Biology.

Chromatin regulation by RUNX1.

C. Bonifer, M. Hoogenkamp, Monika Lichtinger, 2010, Blood cells, molecules & diseases.

Identification of a Dynamic Core Transcriptional Network in t(8;21) AML that Regulates Differentiation Block and Self-Renewal

Salam A. Assi, D. Tenen, D. Westhead, 2014, Cell reports.

PAP-LMPCR for improved, allele-specific footprinting and automated chromatin fine structure analysis

A. Riggs, C. Bonifer, M. Hoogenkamp, 2008, Nucleic acids research.

Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemia.

D. Tenen, V. Lefebvre, D. Scadden, 2013, Cancer cell.

Sox4 Is aK ey Oncogenic Target in C/EBPa Mutant Acute Myeloid Leukemia

D. Tenen, D. Scadden, Hong Zhang, 2013 .

The in vivo regulation of the carbamoylphosphate synthetase I gene

M. Hoogenkamp, Lamers, Jacqueline L. M. Vermeulen, 2007 .

In vivo footprinting of the carbamoylphosphate synthetase I cAMP-response unit indicates important roles for FoxA and PKA in formation of the enhanceosome.

W. Lamers, M. Hoogenkamp, I. Gaemers, 2006, Biochimie.

Runx proteins regulate Foxp3 expression

A. Fisher, C. Bonifer, S. Hadjur, 2009, The Journal of experimental medicine.

T-ALL Proliferation Relies on Glutamine Uptake and EAAT1-dependent Conversion of Glutamine to Aspartate and Nucleotides

U. Günther, C. Ludwig, M. Reed, 2023, bioRxiv.

Depletion of WFS1 compromises mitochondrial function in hiPSC-derived neuronal models of Wolfram syndrome

S. Sarkar, D. Ward, Malgorzata Rak, 2023, Stem cell reports.

Structural requirements of the glucocorticoid-response unit of the carbamoyl-phosphate synthase gene.

J. Ruijter, A. Das, W. Lamers, 2004, The Biochemical journal.

Structurall requirements of the glucocorticoid-responsive unitt of the carbamoylphosphate-synthetase gene

J. Ruijter, W. Lamers, O. Schoneveld, 2007 .

Identification of a Dynamic Core Transcriptional Network in t(8;21) AML that Regulates Differentiation Block and Self-Renewal

Salam A. Assi, D. Tenen, D. Westhead, 2014, Cell reports.

cyclicAMP and glucocorticoid responsiveness of the rat carbamoylphosphate synthetase gene requires the interplay of upstream regulatory units.

W. Lamers, O. Schoneveld, M. Hoogenkamp, 2007, Biochimie.

The hematopoietic master regulator RUNX1 reshapes the epigenetic landscape at the onset of hematopoiesis

Salam A. Assi, B. Göttgens, V. Kouskoff, 2013, Epigenetics & Chromatin.

Runx proteins regulate Foxp3 expression

A. Fisher, C. Bonifer, S. Hadjur, 2009, The Journal of experimental medicine.

Identification of a Dynamic Core Transcriptional Network in t(8;21) AML Regulating Differentiation Block and Self-Renewal

Salam A. Assi, D. Tenen, D. Westhead, 2014 .

Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemia.

D. Tenen, V. Lefebvre, D. Scadden, 2013, Cancer cell.

Thee cyclicAMP-response unit in the distal enhancer of thee rat carbamoylphosphate-synthetase gene is a bifunctionall element

W. Lamers, O. Schoneveld, M. Hoogenkamp, 2007 .

Macrophage development from HSCs requires PU.1-coordinated microRNA expression.

F. Rosenbauer, D. Lenze, S. Heinz, 2011, Blood.

Identification of a Dynamic Core Transcriptional Network in t(8;21) AML that Regulates Differentiation Block and Self-Renewal

Salam A. Assi, D. Tenen, D. Westhead, 2014, Cell Reports.